← Back to search
9b62

Human RANBP2/RAN(GTP)/RANGAP1-SUMO1/UBC9/CRM1/RAN(GTP) - composite map and model

Method: ELECTRON MICROSCOPY
▼

1. Protein Identity and Related Structures Protein Identity & Related Structures

Exportin-1

Homo sapiens

UniProt O14980

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 7 GTP-binding nuclear protein Ran × 2 （P62826） SUMO-conjugating enzyme UBC9 × 1 （P63279） Small ubiquitin-related modifier 1 × 1 （P63165） E3 SUMO-protein ligase RanBP2 × 1 （P49792） Ran GTPase-activating protein 1 × 1 （P46060） GUANOSINE-5'-TRIPHOSPHATE × 2 MAGNESIUM ION × 2 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
4bsm 4bsn 9og9 9oga

4 assemblies

Homodimer
1w9c

1 assemblies

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
2l1l 3gb8 5dis 6tvo 7b51 8urj 9b62 9hfl 9ogb 9ogc 9ogd 9oge

13 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name XPO1_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 4–1074； UniProt 1–1071

GTP-binding nuclear protein Ran

Homo sapiens

UniProt P62826

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 7 Exportin-1 × 1 （O14980） SUMO-conjugating enzyme UBC9 × 1 （P63279） Small ubiquitin-related modifier 1 × 1 （P63165） E3 SUMO-protein ligase RanBP2 × 1 （P49792） Ran GTPase-activating protein 1 × 1 （P46060） GUANOSINE-5'-TRIPHOSPHATE × 2 MAGNESIUM ION × 2 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
2mmc 2mmg 2n1b 3gj0 3gj0 5ciq 5ciq 5cit 5cit 5ciw 5ciw 5cj2

19 assemblies; showing the first 12

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
1i2m 1i2m 1i2m 1ibr 1ibr 1k5d 1k5d 1k5d 1k5d 1k5g 1k5g 1k5g

185 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name RAN_HUMAN
Isoform —
PDB entities 2
Chains and sequence ranges Author chain B； PDBConstruct 7–222； UniProt 1–216 Author chain F； PDBConstruct 7–222； UniProt 1–216

SUMO-conjugating enzyme UBC9

Homo sapiens

UniProt P63279

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 7 Exportin-1 × 1 （O14980） GTP-binding nuclear protein Ran × 2 （P62826） Small ubiquitin-related modifier 1 × 1 （P63165） E3 SUMO-protein ligase RanBP2 × 1 （P49792） Ran GTPase-activating protein 1 × 1 （P46060） GUANOSINE-5'-TRIPHOSPHATE × 2 MAGNESIUM ION × 2 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1a3s 3a4s 3a4s 5f6d 5f6e 5f6u 5f6v 5f6w 5f6x 5f6y 9glr

11 assemblies

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
1kps 1kps 1z5s 2grn 2gro 2grp 2grq 2grr 2o25 2o25 2pe6 2px9

29 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name UBC9_HUMAN
Isoform —
PDB entities 3
Chains and sequence ranges Author chain C； PDBConstruct 4–161； UniProt 1–158

Small ubiquitin-related modifier 1

Homo sapiens

UniProt P63165

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 7 Exportin-1 × 1 （O14980） GTP-binding nuclear protein Ran × 2 （P62826） SUMO-conjugating enzyme UBC9 × 1 （P63279） E3 SUMO-protein ligase RanBP2 × 1 （P49792） Ran GTPase-activating protein 1 × 1 （P46060） GUANOSINE-5'-TRIPHOSPHATE × 2 MAGNESIUM ION × 2 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1a5r 2mw5 2n1v 5b7a 5elj 5ghd 6j4i

7 assemblies

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
1tgz 1tgz 1wyw 1y8r 1y8r 1z5s 2asq 2bf8 2g4d 2g4d 2io2 2iy0

87 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name SUMO1_HUMAN
Isoform —
PDB entities 4
Chains and sequence ranges Author chain D； PDBConstruct 5–101； UniProt 1–97

E3 SUMO-protein ligase RanBP2

Homo sapiens

UniProt P49792

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 7 Exportin-1 × 1 （O14980） GTP-binding nuclear protein Ran × 2 （P62826） SUMO-conjugating enzyme UBC9 × 1 （P63279） Small ubiquitin-related modifier 1 × 1 （P63165） Ran GTPase-activating protein 1 × 1 （P46060） GUANOSINE-5'-TRIPHOSPHATE × 2 MAGNESIUM ION × 2 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1xke 4ga0 4i9y 4i9y 4i9y 4i9y 4i9y 4i9y 4l6e 7mnj 7mnj 7mnj

12 assemblies

Homodimer

None

Homotetramer
7mnk

1 assemblies

Other homooligomers

None

Heteromeric or nucleic-acid complex
1rrp 1rrp 1rrp 1rrp 1z5s 3uin 3uio 3uip 4lqw 4lqw 5cll 5cll

56 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name RBP2_HUMAN
Isoform —
PDB entities 5
Chains and sequence ranges Author chain E； PDBConstruct 5–619； UniProt 2446–3060

Ran GTPase-activating protein 1

Homo sapiens

UniProt P46060

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 7 Exportin-1 × 1 （O14980） GTP-binding nuclear protein Ran × 2 （P62826） SUMO-conjugating enzyme UBC9 × 1 （P63279） Small ubiquitin-related modifier 1 × 1 （P63165） E3 SUMO-protein ligase RanBP2 × 1 （P49792） GUANOSINE-5'-TRIPHOSPHATE × 2 MAGNESIUM ION × 2 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
1z5s 2grn 2gro 2grp 2grq 2grr 2io2 2io3 2iy0 3uin 3uio 3uip

15 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name RAGP1_HUMAN
Isoform —
PDB entities 6
Chains and sequence ranges Author chain G； PDBConstruct 5–591； UniProt 1–587

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

▼

2. Structure Basics 2. Structure Basics

Entry ID entry_id9b62
Deposition date deposition_date2024-03-23
Structure title titleHuman RANBP2/RAN(GTP)/RANGAP1-SUMO1/UBC9/CRM1/RAN(GTP) - composite map and model
Keywords keywordskaryopherin, SUMO E3, SUMO E2, transporter, GTPase, GTPase activating protein, exportin, G-protein, TRANSPORT PROTEIN; TRANSPORT PROTEIN
Experimental Method methodELECTRON MICROSCOPY
▼

3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

9b62__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

9b62__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 109 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

9b62__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）52.90 Å
Rg (electron density)52.80 Å
Total Rg52.84 Å
Atom count19287
Residues2414
Excluded volume345820 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 9b62__assembly_1__model_1 heptameric （7） Success 4.1.3-1-20251215 (887e7ef) View Download
▶

4. Crystallography and Experiment 4. Crystallography & Experiment

▶

5. Entities and Polymers Entities & Polymers (8)

▶

7. Citations (1)