SAXSdb — 9kay

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1. Protein Identity and Related Structures Protein Identity & Related Structures

Ferritin heavy chain, N-terminally processed

Homo sapiens

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein homooligomer	Homooligomer	Protein 24	No other associated polymer	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	FRIH_HUMAN
Isoform	—
PDB entities	1
Chains and sequence ranges	Author chain Aa； PDBConstruct 1–159； UniProt 2–160 Author chain Ab； PDBConstruct 1–159； UniProt 2–160 Author chain Ac； PDBConstruct 1–159； UniProt 2–160 Author chain Ad； PDBConstruct 1–159； UniProt 2–160 Author chain Ae； PDBConstruct 1–159； UniProt 2–160 Author chain Af； PDBConstruct 1–159； UniProt 2–160 Author chain Ag； PDBConstruct 1–159； UniProt 2–160 Author chain Ah； PDBConstruct 1–159； UniProt 2–160 Author chain Ai； PDBConstruct 1–159； UniProt 2–160 Author chain Aj； PDBConstruct 1–159； UniProt 2–160 Author chain Ak； PDBConstruct 1–159； UniProt 2–160 Author chain Al； PDBConstruct 1–159； UniProt 2–160 Author chain Am； PDBConstruct 1–159； UniProt 2–160 Author chain An； PDBConstruct 1–159； UniProt 2–160 Author chain Ao； PDBConstruct 1–159； UniProt 2–160 Author chain Ap； PDBConstruct 1–159； UniProt 2–160 Author chain Aq； PDBConstruct 1–159； UniProt 2–160 Author chain Ar； PDBConstruct 1–159； UniProt 2–160 Author chain As； PDBConstruct 1–159； UniProt 2–160 Author chain At； PDBConstruct 1–159； UniProt 2–160 Author chain Au； PDBConstruct 1–159； UniProt 2–160 Author chain Av； PDBConstruct 1–159； UniProt 2–160 Author chain Aw； PDBConstruct 1–159； UniProt 2–160 Author chain Ax； PDBConstruct 1–159； UniProt 2–160

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id	9kay
Deposition date deposition_date	2024-10-30
Structure title title	Bioengineered protein nanocarrier facilitating siRNA escape from lysosomes for targeted RNAi therapy in glioblastoma
Keywords keywords	Bioengineered ferritin, Lysosomal escape, siRNA delivery, Glioblastoma targeted therapy, EGFR and TERT, METAL TRANSPORT; METAL TRANSPORT
Experimental Method method	ELECTRON MICROSCOPY

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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

9kay__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

9kay__assembly_1__model_1 | I(q)

100 plotted points; both axes use logarithmic scales.

9kay__assembly_1__model_1 | P(r) · Pending

P(r) will be calculated and displayed separately for the same assembly/model.

Rg（Guinier）	55.13 Å
Rg (electron density)	53.95 Å
Total Rg	54.29 Å
Atom count	30168
Residues	3624
Excluded volume	531600 Å³
Maximum q	0.500 Å⁻¹

Assembly	Model	Structure unit	Oligomeric description	Status	CRYSOL	Actions
1	1	`9kay__assembly_1__model_1`	24-meric （24）	Success	4.1.3-1-20251215 (887e7ef)	View Download

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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (1)

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Unit-cell length a length_a	1.000 Å
Unit-cell length b length_b	1.000 Å
Unit-cell length c length_c	1.000 Å
Unit-cell angle α angle_alpha	90.00 °
Unit-cell angle β angle_beta	90.00 °
Unit-cell angle γ angle_gamma	90.00 °
Molecules per unit cell Z z_pdb	—

Space group space_group	P 1
Space-group number int_tables_number	1
Crystal system crystal_system	—

Resolution resolution	1.73 Å
Resolution测定Method resolution_method	—
颗粒数 num_particles	966873

Description description	Ferritin heavy chain, N-terminally processed
Molecular weight formula_weight	18673.2 kDa
Mutation mutation	E61K,E64R,E140K,E147K
Source method src_method	man
Copy count entity_count	24

Polymer type type	polypeptide(L)
Chain IDs strand_id	Aa,Ab,Ac,Ad,Ae,Af,Ag,Ah,Ai,Aj,Ak,Al,Am,An,Ao,Ap,Aq,Ar,As,At,Au,Av,Aw,Ax
Atom count atom_count	30168

Bioengineered protein nanocarrier facilitating siRNA escape from lysosomes for targeted RNAi therapy in glioblastoma

1. Protein Identity and Related Structures Protein Identity & Related Structures

Ferritin heavy chain, N-terminally processed

State in the Current Structure

Other States of the Same Protein in the Database

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

9kay__assembly_1__model_1

9kay__assembly_1__model_1 | I(q)

9kay__assembly_1__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

冷冻电镜 EM 3D

5. Entities and Polymers Entities & Polymers (1)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

7. Citations (1)

Source organism organism	Homo sapiens
Common name common_name	human
NCBI taxonomy ID ncbi_taxonomy_id	9606
Host organism host_organism	Escherichia coli

Bioengineered protein nanocarrier facilitating siRNA escape from lysosomes for targeted RNAi therapy in glioblastoma

1. Protein Identity and Related Structures Protein Identity & Related Structures

Ferritin heavy chain, N-terminally processed

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

9kay__assembly_1__model_1

9kay__assembly_1__model_1 | I(q)

9kay__assembly_1__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

冷冻电镜 EM 3D

5. Entities and Polymers Entities & Polymers (1)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

7. Citations (1)