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9wmt

;Co-transcriptional histone H3K36 methylation complex containing RNA polymerase II elongation complex, Set2, and the upstream nucleosome. (temp115, type A) ;

Method: ELECTRON MICROSCOPY D_max: 211.2 Å Quality: EXCELLENT

SAXS Profile

P(r) Distribution

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1. Structure Basics

entry_id	9wmt
deposition_date	2025-09-03
title	;Co-transcriptional histone H3K36 methylation complex containing RNA polymerase II elongation complex, Set2, and the upstream nucleosome. (temp115, type A) ;
keywords	chromatin, nucleosome, TRANSCRIPTION; TRANSCRIPTION
method	ELECTRON MICROSCOPY

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Download Data

SAXS curve (.dat) P(r) distribution (.pr.out) Structure (CIF)

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2. SAXS Parameters (CRYSOL)

rg_guinier	79.72 Å
rg_electron	79.37 Å
i0	19311300000.00
molecular_weight	1122400.0 kDa
excluded_volume	1380700 Å³
envelope_volume	2269900 Å³
shell_volume	235200 Å³
envelope_diameter	287.0 Å
shell_rg	80.51 Å
envelope_rg	78.50 Å
shape_rg	79.36 Å
total_rg	79.40 Å
total_atoms	78546
n_residues	9364
n_harmonics	20
q_range	— – 0.5000 Å⁻¹
n_points	101
shell_type	directional
solvent_density	0.3340 e/Å³
contrast_shell	0.0300 e/Å³
crysol_version	4.1.3

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3. P(r) Analysis (GNOM)

dmax	211.2 Å
rg_real	75.89 Å
rg_real_error	0.57 Å
i0_real	1.8490e+10
i0_real_error	3.3470e+08
rg_reciprocal	79.36 Å
i0_reciprocal	19290000000.0000
total_estimate	0.9178
solution_quality	EXCELLENT a EXCELLENT solution
n_peaks	1
r_peak_primary	95.0 Å
skewness	0.239
kurtosis	-0.500
angular_range	— – 0.1000 Å⁻¹
current_alpha	0.4112
highest_alpha	1908000000.0000
n_real_points	21
gnom_version	4.1.3
quality_criteria	AN1: 0.001; Oscil: 0.996; Stabil: 0.988; Sysdev: 1.000; Positv: 1.000; Valcen: 0.977; Smooth: 0.003

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4. Crystallography & Experiment

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5. Entities & Polymer Info (33)

Entity 1 polymer

description	DNA-directed RNA polymerase subunit
formula_weight	194107.4 kDa
ec_number	2.7.7.6
src_method	nat
entity_count	1

Polymer

type	polypeptide(L)
strand_id	A
atom_count	78546

MSQFPYSSAPLRSVKEVQFGLLSPEEIRAISVVKIEYPEIMDESRQRPREGGLNDPKLGSIDRNFKCQTCGEGMAECPGHFGHMELAKPVFHIGFIPKIKKVCECICMNCGKLLLDETNPTMAQAIRIRDPKKRFNAVWQLCKTKMVCEADAPVDEYSEQKVVSRGGCGNTQPVVRKDGMKLWGTWKKSGFSDRDAQPERKLLTPGEILNVFKHISPEDCFRLGFNEDYARPEWMIITVLPVPPPQVRPSIAMDETTQGQDDLTHKLSDILKANINVQKLEMDGSPQHIINEVEQLLQFHVATYMDNDIAGQPQALQKSGRPVKAIRARLKGKEGRLRGNLMGKRVDFSARTVISGDPNLELDQVGVPISIAKTLSYPETVTQYNIHRLTEYVRNGPNEHPGAKYVIRDNGDRIDLRYHKRAGDIVLQYGWKVERHLMDDDPVLFNRQPSLHKMSMMAHRVKVMPYSTFRLNLSVTSPYNADFDGDEMNLHVPQSEETRAELSQLCAVPLQIVSPQSNKPVMGIVQDTLCGVRKMTLRDTFIEYEQVMNMLFWVPSWDGVVPQPAILKPKPLWTGKQLLSIAIPSGIHLQRTDGGNSLLSPKDNGMLIVDGKVMFGVVDKKTVGSGGGGLIHTVMREKGPKICAELFGNIQKVVNYWLLHNGFSIGIGDAIADASTMKEITHAISSAKEQVQEIIYKAQHNELELKPGMTLRESFEGEVSRTLNDARDSAGRSAEMNLKDLNNVKQMVSAGSKGSFINIAQMSACVGQQMVEGKRIAFGFADRSLPHFTKDDFSPESKGFVENSYLRGLTPQEFFFHAMAGREGLIDTAVKTAETGYIQRRLVKALEDIMVHYDGTTRNSLGDIIQFLYGEDGLDGTQVERQTIDTIPGSDKAFHKRYYVDLMDEKNSIKPDVIEYAADILGDVELQKELNSEYEQLVSDRKFLREIVFVNGDHNWPLPVNLRRIIQNAQQIFHLDRAKASDLTIPEIIHGVRDLCKKLFVLRGENELIKEAQQNATSLFQCLVRARLATRRILEEFRLNRDAFEWVLGTIEAQFQRSLVHPGEMVGVIAAQSIGEPATQMTLNTFHYAGVSSKNVTLGVPRLKEILNVAKNIKTPALTVYLDREIALDIEKAKVIQSSIEYTTLKNVTSATEIYYDPDPTSTVIEEDFDTVEAYFSIPDEKVEETIDKQSPWLLRLELDRARMLDKQLTMNQVADKISEVFSDDLFVMWSEDNADKLIIRCRVIRDPKAMDEELEAEEDQMLKRIEAHMLDLIALRGIPGISKVYMVKHKVSVPDESGEYKNEELWALETDGINLAEVMAVPGVDSSRTYSNSFVEILSVLGIEATRSSLYKEILNVIAFDGSYVNYRHMALLVDVMTSRGYLMAITRHGINRADTGALMRCSFEETVEILFEAGAAAELDDCRGVSENVMLGQLAPMGTGAFDVMIDEKLLTSLPADYAPTMPLFKGKATQGSATPYDNNAQYDDEFNHDDVADVMFSPMAETGSGDDRSGGLTEYAGIQSPYQPTSPGLSATSPGFAPTSPGFAPTSPRYSPTSPGYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPQYSPTSPQYSPTSPQYSPTSPQYSPTSPQYSPTSPQYSPTSPQYSPTSPQYSPTSPQYSPTSPQYSPTSPQYSPTSPQYSPTSPQYSPTSPQYSPASPQYSPSRHSPNGESKEGE

Entity 2 polymer

description	DNA-directed RNA polymerase subunit beta
formula_weight	139746.1 kDa
ec_number	2.7.7.6
src_method	nat
entity_count	1

Polymer

type	polypeptide(L)
strand_id	B

MSYDPYSIDDTITTEDCWTVISAFFEEKGLVSQQLDSFDEFMETSIQDLVWEEPRLILDQPAQHTNEKDNINKRYEIRFGKIYLSRPTMTEADGTTHAMFPQEARLRNLTYSSPVYLDMEKSMFTSIDDEGNPNATLDWQQVHEPIKDGVEEGNKVHIGKVPIMLRSKFCSLRTLDEVDLYKMKECPYDMGGYFVINGSEKVLIAQERSAANIVQVFKKAAPSPISHVAEIRSALEKGSRLISTMQIKLYGREDKGTGRTIKATLPYVKQDIPIVIVFRALGVVPDGEILQHICYDENDWQMLEMLKPCIEEGFVIQDKEVALDFIGRRGSAALGIRREKRIQYAKDILQKELLPHITQEEGFETRKTFFLGYMVNRLLLCALERKDQDDRDHFGKKRLDLAGPLLANLFRILFRKLTREIYRYMQRCIETDRDFNLNLAVKSTTITSGLKYSLATGNWGEQKKAMSSRAGVSQVLNRYTYSSTLSHLRRTNTPIGRDGKLAKPRQLHNTHWGLVCPAETPEGQACGLVKNLSLLSGISIGSPSEPIINFLEEWGMEPLEDYDPAQHTKSTRIFVNGVWTGIHRDPSMLVSTMRDLRRSGAISPEVSIIRDIREREFKIFTDVGRVYRPLFIVEDDESKDNKGELRITKEHIRKIQQGYDDDAMNDDSEEQEQDVYGWSSLVTSGVIEYVDGEEEETIMIAMTPEDLQTRSLEQKEIDLNDTAKRIKPEMSTSSHHTFTHCEIHPSMILGVAASIIPFPDHNQSPRNTYQSAMGKQAMGVFLTNYNVRMDTMANILYYPQKPLAKTQAMEYLKFRELPAGQNAIVAIACYSGYNQEDSMIMNQSSIDRGLFRSLFFRSYMDQEKRFGISIVEEFEKPTRATTLRLKHGTYEKLDEDGLIAPGVRVSGDDIIIGKTTPIPPDTEELGQRTKYHTKRDASTPLRSTENGIVDQVLLTTNQEGLKFVKVRMRTTKVPQIGDKFASRHGQKGTIGVTYRHEDMPFSAEGIVPDLIINPHAIPSRMTVAHLIECLLSKVGSIRGYEGDATPFTDLTVDAVSNLLRDNGYQSRGFEVMYNGHTGKKLMAQVFFGPTYYQRLRHMVDDKIHARARGPVQVLTRQPVEGRSRDGGLRFGEMERDCMIAHGAAGFLKERLMEASDAFRVHVCGICGLMSVIANLKKNQFECRSCKNKTNIYQLHIPYAAKLLFQELMAMNIAPRLYTERSGVSMRS

Entity 3 polymer

description	RNA polymerase II third largest subunit B44, part of central core
formula_weight	34216.3 kDa
src_method	nat
entity_count	1

Polymer

type	polypeptide(L)
strand_id	C

MSKEPKVNIINAQDDEVELMLSDVNLSLANSLRRTMLAEVPTLAIDLVEIKMNTSVLADEFISHRLGLIPLVSEDVEEMKYSRDCTCEDYCDECSVVLELSARHEGEEGTTDVYSSSLIKVSGPGNLNVGEPVRRDDYDQGILLCKLRNHQELNIRCIAKKGIAKEHAKWSPCSAIAFEYDPHNKLKHTDFWFEVDAKKEWPDSKYATWEEPPKPGEVFDYKAKPNRFYMTVETTGSLKANQVFSRGIKTLQEKLANVLFELENSRPANTTAYGGATAYGGQTVYGRETSYGGNTNYGDYNAPY

Entity 4 polymer

description	RNA polymerase II subunit B32
formula_weight	20623.0 kDa
src_method	nat
entity_count	1

Polymer

type	polypeptide(L)
strand_id	D

MNVSTSTVGARRRRAKQQVDDEENATLLRLGPEFALKQYDHDGNEHDLIALSLSESRLLIREALKARSRARNGGVDIESSNGEIDDDELAKVTSGAVANGVVKKTLDYLNTFARFKDEETCTAVDQLLHNSSDCSVLHPFEIAQLSSLGCEDVDEAITLIPSLAAKKEVNLQRILDELNRLEDPYK

Entity 5 polymer

description	DNA-directed RNA polymerases I, II, and III subunit RPABC1
formula_weight	24962.7 kDa
src_method	nat
entity_count	1

Polymer

type	polypeptide(L)
strand_id	E

MEDNNRIISRLWRSFRTVKEMAADRGYFISQEEMDQSLEEFRSKICDSMGNPQRKLMSFLANPTPEALEKYSDLGTLWVEFCDEPSVGIKTMRNFCLRIQEKNFSTGIFIYQNNITPSANKMIPTVSPAIIETFQESDLVVNITHHELVPKHIRLSDGEKSQLLQRYKLKESQLPRIQREDPVARYLGLKRGQVVKIIRRSETSGRYASYRICL

Entity 6 polymer

description	RNA polymerase subunit ABC23, common to RNA polymerases I, II, and III
formula_weight	17803.6 kDa
src_method	nat
entity_count	1

Polymer

type	polypeptide(L)
strand_id	F

MSEDEAFNEQTENFENFEDEHFSDDNFEDRSTQPEDYAVGVTADGRQIINGDGIQEVNGTIKAHRKRSNKELAILKEERTTTPYLTKYERARILGTRALQISMNAPVLVDIEGETDPLQIAMKELSQRKIPLVIRRYLPDGSYEDWGCDELIVDN

Entity 7 polymer

description	RNA polymerase II subunit
formula_weight	18802.6 kDa
src_method	nat
entity_count	1

Polymer

type	polypeptide(L)
strand_id	G

MFFLKDLSLILTLHPSYFGPQMNQYLREKLLTDVEGTCTGQFGYIVTVLDGMNIDVGKGRIIPGSGSAEFEVKYRAVVWKPFKGEVVDAIVSNVSPIGFFADVGPLNVFVSTRLIPDNLVYNPSNSPPAYMSNDELITKGSKVRLKVVGTRTDVNEIYAIGSIKEDFLGAI

Entity 8 polymer

description	DNA-directed RNA polymerases I, II, and III subunit RPABC3
formula_weight	16249.2 kDa
src_method	nat
entity_count	1

Polymer

type	polypeptide(L)
strand_id	H

MSSALFDDIFTVQTVDNGRYNKVSRIIGISTTNSAIKLTLDINNEMFPVSQDDSLTVTLANSLSLDGEDESANFSKSWRPPKPTDKSLADDYDYVMFGTVYKFEEGDEDKIKVYVSFGGLLMCLEGGYKSLASLKQDNLYILIRR

Entity 9 polymer

description	DNA-directed RNA polymerase subunit
formula_weight	13612.3 kDa
src_method	nat
entity_count	1

Polymer

type	polypeptide(L)
strand_id	I

MASFRFCLECNNMLYPKEDKENQRLLYSCRNCDYTELAEDPKVYRHELITNIGETAGIVDDIGQDPTLPRSDKECPECHSRDCVFFQSQQRRKDTNMTLFYVCLNCKKTFRDESE

Entity 10 polymer

description	RNA polymerase subunit ABC10-beta, common to RNA polymerases I, II, and III
formula_weight	8554.1 kDa
src_method	nat
entity_count	1

Polymer

type	polypeptide(L)
strand_id	J

MIIPVRCFSCGKVVGDKWDAYLRLLEEGKQEGDALDELKLKRYCCRRMVLTHVDLIEKFLRYNPLEKKDFDS

Entity 11 polymer

description	RNA polymerase II subunit B12.5
formula_weight	13832.9 kDa
src_method	nat
entity_count	1

Polymer

type	polypeptide(L)
strand_id	K

MNAPDRFELFILPDDVPKLKITPDSRVPNCIIIKFEREDHTLANLLREELALYPDVTFVAYKVEHPLFANFVMRLQTEEGTRPKQALERACASIINKLKTLDHKFNEEWNIKNFSLND

Entity 12 polymer

description	RNA polymerase subunit ABC10-alpha
formula_weight	7862.0 kDa
src_method	nat
entity_count	1

Polymer

type	polypeptide(L)
strand_id	L

MSREGFVAPSGTDLAAAASGVAPNKHYGVKYTCGACAHNFSLNKSDPVRCKECGHRVIYKARTKRMIQFDAR

Entity 13 polymer

description	Transcription elongation factor 1 homolog
formula_weight	12606.9 kDa
src_method	man
entity_count	1

Polymer

type	polypeptide(L)
strand_id	M

GPGMGKRKSSARKPAPKIKQKLETQFTCLFCNHDNSVVCTLDKKNSIGLLECKKCNLSFQAPINSLSQPIDIYSDWIDACEAVAEENADVNGDNFIENDGADREQDDDYDDEF

Source

organism	Komagataella phaffii GS115
ncbi_taxonomy_id	644223
host_organism	Escherichia coli

Entity 14 polymer

description	DNA (198-MER)
formula_weight	61264.7 kDa
src_method	syn
entity_count	1

Polymer

type	polydeoxyribonucleotide
strand_id	N

GCTTACGTCAGTCTGGCCATCTTTGTGTTTGGTGTGTTTGGGTGGTGGCCGTTTTCGTTGTTTTTTTCTGTCTCGTGCCTGGTGTCTTGGGTGTTTTCCCCTTGGCGGTTTTTTCGCGGGGGTCTGCGCGTTCGTGCGTTTTTGCGGTGCTTGTGCTGTCTTCGTCCAAAAGAGCGGCCTCGGCACCGGGATTCTGAT

Entity 15 polymer

description	;RNA (5'-R(PGPCPUPUPGPUPGPCPUPGPUPCPUPUPCPGPUPCPCPA)-3') ;
formula_weight	6290.7 kDa
src_method	syn
entity_count	1

Polymer

type	polyribonucleotide
strand_id	P

GCUUGUGCUGUCUUCGUCCA

Entity 16 polymer

description	DNA (198-MER)
formula_weight	60987.2 kDa
src_method	syn
entity_count	1

Polymer

type	polydeoxyribonucleotide
strand_id	T

ATCAGAATCCCGGTGCCGAGGCCGCTCTTTTGGACGAAGACAGCACAAGCACCGCAAAAACGCACGAACGCGCAGACCCCCGCGAAAAAACCGCCAAGGGGAAAACACCCAAGACACCAGGCACGAGACAGAAAAAAACAACGAAAACGGCCACCACCCAAACACACCAAACACAAGAGCTAATTGACTGACGTAAGC

Entity 17 polymer

description	Transcription elongation factor SPT4
formula_weight	12039.6 kDa
src_method	man
entity_count	1

Polymer

type	polypeptide(L)
strand_id	V

MRERACMLCGIVLPGRVFMQNGCPNCDSVLNLRDSDQATVNECTSSSFEGLVAVGDNEHSWVAKWLRVDRFQPGLYAVRVDGRLPSDIVAALEQYGVYYRPRDGSVID

Source

organism	Komagataella phaffii GS115
ncbi_taxonomy_id	644223
host_organism	Escherichia coli

Entity 18 polymer

description	Transcription elongation factor SPT5
formula_weight	101459.4 kDa
src_method	man
entity_count	1

Polymer

type	polypeptide(L)
strand_id	W

GPGMSETHKNQLDKVSTVSPDGPSEAVKEHSLQSKDLSKNDGQFIVPLDRNVIEQEEHKQVKSSAQAHNTTGDAADNEIEDGVPSEDVEFDKFKEDDYDEDDEVEEEGDIRSRKRRRHNQFLDVEAEVDDEEDDDDDDDDVELKHDFIQDDHIQHETQNEGFIAGHVDDDRLHRKLDQSREKIADQDAQELADEFKQRYGRSASSKYMGSASTTAPQRLLIPTVDDPGIWGVKVRLGKEKDVVRQILKKKLAREGTKNPLEIYSAFQRDSFKGHVYIEARKAEAINDALKGNVNVFSNNSKFLVGIVEYKDLLRPVKSSDVKLTRGSYVRVKNGKFKGDLAQVDEVLENGLEARLKLVPRLDYGKDLSHLSTSSSVDSTKNRRKFYTSKFRPAQRLFSEAEARVHEPTIRRDRDGFVTYGGEEYYEGFLYKTFRLQNLIVNSINPTLNELSLFQSNEESTTIDLSTIADSLKETAKNLVSFQPGDNVEIINGELNHLTGTVSSVNQSTIVSVRLHSDDDTINSETVEIPTSDLRKIFNVGDHVRVIHGKHTDDTGLIVEVNGDKVEFISNQTKRTVIVFSNYLIKSTDSTVSINESGRFELHDLVQVNSDLVGIVIRAQKDSFDVLCSDGKLLSLPPVSIYSKLNLNPNQQIAIDSNGVEVKVGDTVREFTGERRQGTILHVYRNFLFLRSREIVENQGVFVTSSNRVKTITSKSNGTGGQISGPDLSRMNPSRVIPPPSIPVANQRMTGRDPTLNKTVKIRQGGYKGKIGIVKEANGDRFRVELHNPNKTIPIPCSFLLIESTHGWVPYEDFVASDRRGGNIPRHEISGHVQQPQHGRAPAWGSGGKTPAWGSGGKTPAWGSGGSGGKTPAWGSGGKTPTWGSGAKTPAWGSGSKTPAWSGLDEEDRRDF

Source

organism	Komagataella phaffii GS115
ncbi_taxonomy_id	644223
host_organism	Escherichia coli

Entity 19 polymer

description	Transcription elongation factor Spt6
formula_weight	173241.6 kDa
src_method	man
entity_count	1

Polymer

type	polypeptide(L)
strand_id	m

GPGMSAPSPSVSEEDINETRNSIDADASTVQDLLDQDAQEGSGSDNEGSNIVDSSEEDDDEDDEEEMQKVREGFIVDDDDENDEDGIPSSTKRKHRKKHKKRSAEVVEEVDEDDLQLLMENSGAVPGQQQNVKFKRLKRAEQDEKAQDSDSRGLNDMFSDEEGPGGVVEEGSEEEGLEDNLTTKTQRSGNLPHDEFDDFIEEDEFSDEDDEARDERLARMRSAKAAPQLAGLQGEQYQEIIEIFGDGTDYQWTLDAEEEMEQPQQDQEYDEAGEEIKGTTTSLADVFEPSELKEKMLTDEDNVIRVTDLPERFQAYRKSIKNYKLSDVDYSNERDWIVEQLKLEKRDFLQHLTQAHSSVAHLEEKFEASVKKIVDFIAIESFEVPFIWNHRRDYALHTYNDDSNNTIIVKLLNEDDLWRIVQLDLDYHSIHDKKAALSSIYKQLDLDVVDPTYEEFFGSARTLSELQDIDDYLTFNYSSQVKNLTAVAELSIEGNGSGEDEEQTTKSSFAEVKMKRKYSKYAIYDRIRQDAIYPVVQSIANISQMRENLAQSKRLHQVEDPIESPMDMIADIMSTEKDKTTFISSEKAYQAVKQFFSEQLSYEPFIRKTIRTAFQSFGVINIELTERGKLQIEPESPYFDFKYAKNRPISALTATPDLYLRMIQAENDGLVNIKVELPMLSTVVDHFYNILKSDGTSEISEKWNALRNDAWKQSLDKLIPLVQLNVKESIRRDCERVLYFQVKNSFTKKIDQAPYQPPTYAKGTIPRVLTLSFGEGNRGDAVLGVFMDDSGDVKSQIKFDEDFQSRDFSDSLTRYIKSNNINPDIIGISGFNIHTKKLFDKVNELVNEERLTIEYDNEYGYDREEDGRSDKHLIRVIYVNDETARLYQHSSKSSAEYPNRPQLAKYCIGLAKYIQSPLLEYLALDESMYSLHIHKHQNLLPREKLIDAVQTSIVDIVNLVGVDINEAVRAPYHALALPYVCGLGPRKAAGLIQSIQRIGSNLVNRAHLITEQLTSKTVFLNMASFVYIVFDPDVERNPQGEMDLLDSTRIHPEDYSLARKMAADALDIEDIDDDDESAMRNAIYEMVFPRSPPKDEDDLTFKLDELILDDYATELERKHQLKKRSTLQIIKEELQSRYREIRRDFHILNEAEIFQLLTRETVDSFRKGMVIPVYVRKVESSYMSVSTQSLIAGNIQRQDILEPNDRRDPREVYSVGQTVRACILDVDYYNFKCQLSLLRQFTENQVAGLNVNRNPKFWDIESENRDRQEEIDKQREESRESRVIKHPFFHNMKSKEAEDYLAARPVGDVVIRPSSKGSNHITISWKVAPQLYQHIDVLEENKDDANAIGRVLLVGKYRYHDLDELLVEYVNNVANKVELMVSHDKFMSDSLDYVKEWLERYSKANGNRSHYIFTFNRKAPGWFFLLFKLNPTSEIKIWNVKALPDGYLLANNVYPDTNSLCNGFKTLMSSRRQIKQRSNRAGGEYNNSHAGAYDNGYSNAPRY

Source

organism	Komagataella phaffii GS115
ncbi_taxonomy_id	644223
host_organism	Spodoptera frugiperda

Entity 20 polymer

description	Protein that interacts with Spt6p and copurifies with Spt5p and RNA polymerase II
formula_weight	46907.8 kDa
src_method	man
entity_count	1

Polymer

type	polypeptide(L)
strand_id	n

GPGMSDEESENKKLLDQVLPEKTDQETQPEADAALAEQEAPENEPNEPASDDDSDSDLSDISDVDEEKVAEGLRYLDEQTAASLSKHKAAQPSSTHKKKEPTRRRPKQQTARETQYEPDVVEDEAARRTRLFEEKLDAAIKRKPNKRKKNDDVDLEQMQDELIQQLKLQMEESAIRDANNIEQGKPAIFKLKLLPKVKDILLRANLADSILDNNLLASVRLWLEPLPDASLPAYQIQKVLFDAIKSLPIKTSHLRESGLGKVMVFYQKSKRVEPNLKRTAEKLISDWTRPIMGASDNYKDMRVRTQQFDPAQFAESLPGRVSVRPQEAKTLYEEAAERRKRAAIPQARTAAYTIAPQVNTELLMSSARRTLPSGVGSSLSGEDQYKRLNSRLNTMGTKRKSSAKKGGISIEGRGLPQ

Source

organism	Komagataella phaffii GS115
ncbi_taxonomy_id	644223
host_organism	Escherichia coli

Entity 21 polymer

description	Component of the Paf1p complex
formula_weight	124979.0 kDa
src_method	man
entity_count	1

Polymer

type	polypeptide(L)
strand_id	q

MKDHLIHNHHKHEHAHAEHDYKDDDDKEHLYFQGSSGSSGMSLLDQDYYLSALPEDKRAELVTLQLTIPLKSGDEVVTIDFNEDVDVSQLCVLLESENARPDLWLSAAKVFVSKGNIAGSQEIIRKALQSNVILDSSASVTSLFHNFSFWLSLMEYVSTNSREDQFLEYASNSLQASNSLDSGLILNGIGNGVLYAKSRRYDEALKEFDNLLKKKSTNILAILGKAQILYKRQKYSQALELYQKALTINPLIVPDPRLGIGLCFWHLNNKQLAEQAWHNSLKVHPQNNLNTKILICLAKFDYCFNESKDDDEFTALYRESLEFLHSCLKEDAKHPLLLMVLASYYFSKEDYEKVEKLCNLVLKENSRNAAFVSASHFWLARVAYHKEDYVQAQKQFKQAEDSQNSNTLAKLGYAQCLIARNEVGDATIYLEKFFKENQDSKSSEMMLLLGIIYSQSGKSYYKAIIFLEKYVAVCQEENYPILPEAYLVLSRVYENKDLNVALDYLMKANDILGDKANVYVLNNLGIYHFFRNNVSQSSDFFAQSLEALNNVSPQNKEALSITLHYNKARVEEVSNQSEAEKLYSKLMEKCPGYTSNKIRYIYLLALKSNGNNYADVQQLLDDFPSDLEVRSFYGWFLKRYGRKNGLKQDLESQHHKDTLINYDKHDCYALLSLGNIYATIAREMKVTDQKQNEIKRQQYLRAAQFYHKVLSIDPKNIYAAQGIAIIFSDKERTGLALEIFKKVRDTVQDLGTFINLGHCFMEAKQFGKAIESYTIALEKFSNGMDSKLLVLIGRAWYHRGFYEKSMDAYKKALEVSEQAYQLSKLPALRFNIVFIQFQIADFVKSLPNTQRDLTTLENALSGLNDAIKSLLKLAELEQPPYPSEDLKARATMGSNTLRNQLERAIQDQQDYEMSIQEKLRTARRKQQLDEEKRLEQEQRRLEEARKRQEAELIKRQELIKQAEEWNKMDIDAAKDNNDVLSEDGGEGEKKTTKKRKRKQKVSEDIAPDLDRINEENGNTEDYDPILDNEEEENYDEKDSENKENGQNGQNEEVYPESEGDDEDDVTNTKRQKRSKGIVDEEDSE

Source

organism	Komagataella phaffii GS115
ncbi_taxonomy_id	644223
host_organism	Escherichia coli

Entity 22 polymer

description	RNAPII-associated chromatin remodeling Paf1 complex subunit
formula_weight	62301.2 kDa
src_method	man
entity_count	1

Polymer

type	polypeptide(L)
strand_id	r

MKDHLIHNHHKHEHAHAEHLYFQGSSGSSGMSDKEQDLDEDLLALAGAGSDSESNSAYSPEQEVSRKSKKIVNDSEDENNDSDGEQLLNPYPLEDKFKDEADRARLLGLSEMEREAILYERSQEVIKLKEKHLLSLRAKQSQLEKTAREGPKSSKTNKLSELKKQREQKSKRQRSDEYSDEEDDYRYEEVGDNDDVEMSDNYIDEDDAVFVEPKKSSRSQELSKPATLSDINKIIFGRTAMSKYWYYPEFDDVVKGMYLRLNTGSGGNGFSPYKVVEVLGSQRIKGSAYGLNSKENNCDMYLKVAFPNQKEMVRPLFVFSDSSITHPEFDLFLRELDAEGLSVMDLRDVDYKYHQLKEMSSRSLSNDEVNSIVKMKQSLSSNTGFNTVLKKAQLQEELEEARDAHDHERVARIEAELKSIGAESVVASKASSSMLKIDQRNKKLNNRFIRKAEMAAVEKRKLRGTSESDPFYRLATTARMFYKSANLGADDSNQPKTKAELEEEAKQEKKLEMQKLESMVKSNYRNGGLDRIISKIDFDFDLEL

Source

organism	Komagataella phaffii GS115
ncbi_taxonomy_id	644223
host_organism	Escherichia coli

Entity 23 polymer

description	Histone-lysine N-methyltransferase, H3 lysine-36 specific
formula_weight	83724.5 kDa
ec_number	2.1.1.359
src_method	man
entity_count	1

Polymer

type	polypeptide(L)
strand_id	s

GPGMRERTVSDEEVDNYGHASHFKRKVQIYDYPADKTEEALTTFKTLSQNSYQNKTLGNAHNGRSTADGMSCDCEENWDTVSGINNACGEYSECINRLTSIECISGTCSCGDDCQNQRFQKKQYAPIAVFETEKKGYGVRAQADIRQDAFIYEYLGEVIDESTFRKRKENYDNQGLEHFYFMMLQKGEFIDATAKGGLGRFCNHSCRPNAYVDKWEVGNKLRMGIFAKREIYKGEEICFDYNVDRYGANPQKCYCGEDNCIGFLGGRTQTDSANILPVPIAEALGSTNAQEQRWVRLMKEQNKSIKASDYSSINEDYVNSLEMRPIADKDEASKVTSALLKTQDYIILRKLIERVSLTKDPEVLKEIVRLRGYQCVANILTMIVLDQEQQQVDVESFTLSVLDMLESWPNSSRNRISSSQIESVLESVKTKLKKIQPIGKKINSLLNSWSKLEISYKIPKSQSVGASNDVDNGHAESSTFQLRDEQKENNAASKISPFRIVDNMLLPEQWRWAVDESTGANYYYNKSQNITQWDLPPGCELLNIEVSEKNRDKKPPIDKSRLELKERQRKQEYERVKKEREREKLRLQREQEQEEQRRTETLKKIIANAEAKQQLLSKRLADEENEGKKRHKKSKRPTREQEWNKLFATVVPNMIKKHESQIGRDNLKHCAKDIVHQLSSKEIKKDTSKKPPKELSSEKKAKVKAFVGPYMEKYLDKWKAKHEKK

Source

organism	Komagataella phaffii GS115
ncbi_taxonomy_id	644223
host_organism	Escherichia coli

Entity 24 polymer

description	Leo1
formula_weight	52387.7 kDa
src_method	man
entity_count	1

Polymer

type	polypeptide(L)
strand_id	u

MKDHLIHNHHKHEHAHAEHLYFQGSSGSSGMSQELEQNRHSGEESPDPVLDANTSDVDDDGLDLFGDDDDEQPEAKPGQLDDSSNDAEEDEQEKAGKPEAKVTSHTKSVYDNGETLDISLPIHPKSHIPQGKQDRWVVKLPDFLDINAEPFDPRPFEMNVKTHEDKNQELLDKLIAVNTVRWRYAKSETGGIFKETNSQIIQWEDGTYSLRVGSEIFDMFTTNTDDNYLVSEHNEEGILMTESTLSKSVKLVPASFQSTTHQKLAKALSAKQKKESYARSVVTKEDPEERQRRLESQENERYRLERRRKQAEEEEDYDSYAVSTSRSRPSRASQMYNAADEDDDDDDVAIGRTLASRRNNGYEDDGFIIDDEEEEEAVENDSADEESENEGDDDEEDDEEAAERLNRLKRAGASKYTNEGEQAQSEPVKSEEADNASQRDDAPRKKRRVILDDDEEEEE

Source

organism	Komagataella phaffii GS115
ncbi_taxonomy_id	644223
host_organism	Escherichia coli

Entity 25 polymer

description	RNAP II-associated protein
formula_weight	46046.0 kDa
src_method	man
entity_count	1

Polymer

type	polypeptide(L)
strand_id	v

GSAMTSSKSRQDYIAKVRYQNDLPAPPCPPKLLKYEIEKEAPQKEFLKDSRLLSALFSKDNFRYLMNETSDGLDVNYLRIPGIIENEKSLGKLFSSYKNLAIENLHPDDRLLLVDPNKSATLNEESPVFFLRRPQYVSDGEKINLQNFTNKRKHQDMEDTNPRSQLHSVERTFDEVIDPRNKNRLQSLIHPRKKIKAVKAWHFFPDTSTFDQVFHSLKFVGSASLSKDRPLNEQLGQVSETDSTSVNASILTSLFKPIEINPHNKWISLYAVTDKLSAESFRKSFNSIKDDNIVNRHVIYDHIKDFDQMFRGHKKLFEDFAISFDDISDRAFFVPIVGRLELKKKRIVPGLVDMVNRTNYAHIRMDLRNPSTQETAIRDSRREQYDPVNYSSIQEE

Source

organism	Komagataella phaffii GS115
ncbi_taxonomy_id	644223
host_organism	Escherichia coli

Entity 26 polymer

description	Constituent of Paf1 complex with RNA polymerase II, Paf1p, Hpr1p, Ctr9, Leo1, Rtf1 and Ccr4p
formula_weight	44760.7 kDa
src_method	man
entity_count	1

Polymer

type	polypeptide(L)
strand_id	x

MKDHLIHNHHKHEHAHAEHLYFQGSSGSSGMSEPLIALRQAIKDKKPVGVNEGETIGNAKVLNIGEKQYSLDAPTSFVINGKEFNLKVIYQCWVFRDSSSADYITECEKENIDGISFVERSELISWLKGEITSSAFIKGEKVGITEENGKNEGETKSNNKRKLSDDPLLKEIASNERVLIDHNKVLRGLKPKDFSSVAKDCELRILKEKPANAKSSDSNGRSSTSVSSSSKDARNKEPIIVLSPAASSLVRMSNVKEFLQEGKFLDPSKEPASSSNLLAIQRKSSRFKTPIKLLVVDNVEKLFTKSEYWDRVVAIVTTGKDWQFKNYKYKDPQILFQKFNGFYFKYKGDAVPASVKSWNVKVLDIDRVERFSDRQVVEQFWDTVENTLVAKRYKS

Source

organism	Komagataella phaffii GS115
ncbi_taxonomy_id	644223
host_organism	Escherichia coli

Entity 27 polymer

description	Histone H3.3
formula_weight	15645.3 kDa
mutation	K36M
src_method	man
entity_count	2

Polymer

type	polypeptide(L)
strand_id	a,e

GSHMARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVMKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA

Source

organism	Homo sapiens
common_name	human
ncbi_taxonomy_id	9606
host_organism	Escherichia coli

Entity 28 polymer

description	Histone H4
formula_weight	11676.7 kDa
src_method	man
entity_count	2

Polymer

type	polypeptide(L)
strand_id	b,f

GSHMSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG

Source

organism	Homo sapiens
common_name	human
ncbi_taxonomy_id	9606
host_organism	Escherichia coli

Entity 29 polymer

description	Histone H2A type 1-B/E
formula_weight	14447.8 kDa
src_method	man
entity_count	2

Polymer

type	polypeptide(L)
strand_id	c,g

GSHMSGRGKQGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTESHHKAKGK

Source

organism	Homo sapiens
common_name	human
ncbi_taxonomy_id	9606
host_organism	Escherichia coli

Entity 30 polymer

description	Histone H2B type 1-J
formula_weight	14191.5 kDa
mutation	K121C-ubiquitination mimic
src_method	man
entity_count	2

Polymer

type	polypeptide(L)
strand_id	d,h

GSHMPEPAKSAPAPKKGSKKAVTKAQKKDGKKRKRSRKESYSIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTCYTSAK

Source

organism	Homo sapiens
common_name	human
ncbi_taxonomy_id	9606
host_organism	Escherichia coli

Entity 31 non-polymer

description	ZINC ION
formula_weight	65.4 kDa
src_method	syn
entity_count	13

Entity 32 non-polymer

description	MAGNESIUM ION
formula_weight	24.3 kDa
src_method	syn
entity_count	1

Entity 33 non-polymer

description	S-ADENOSYL-L-HOMOCYSTEINE
formula_weight	384.4 kDa
src_method	syn
entity_count	1

▶

6. Citations (1)

▶

length_a	1.000 Å
length_b	1.000 Å
length_c	1.000 Å
angle_alpha	90.00 °
angle_beta	90.00 °
angle_gamma	90.00 °
z_pdb	—

space_group	P 1
int_tables_number	1
crystal_system	—

resolution	3.59 Å
resolution_method	—
num_particles	35823

fit	/app/data/saxs_computation/wm/9wmt/9wmt.fit
pddf	/app/data/pr_computation/wm/9wmt/9wmt.pr.out
profile	/app/data/saxs_computation/wm/9wmt/9wmt.dat

;Co-transcriptional histone H3K36 methylation complex containing RNA polymerase II elongation complex, Set2, and the upstream nucleosome. (temp115, type A) ;

SAXS Profile

P(r) Distribution

1. Structure Basics

Download Data

2. SAXS Parameters (CRYSOL)

3. P(r) Analysis (GNOM)

4. Crystallography & Experiment

Unit Cell

Symmetry

EM 3D

5. Entities & Polymer Info (33)

Entity 1 polymer

Polymer

Entity 2 polymer

Polymer

Entity 3 polymer

Polymer

Entity 4 polymer

Polymer

Entity 5 polymer

Polymer

Entity 6 polymer

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Entity 7 polymer

Polymer

Entity 8 polymer

Polymer

Entity 9 polymer

Polymer

Entity 10 polymer

Polymer

Entity 11 polymer

Polymer

Entity 12 polymer

Polymer

Entity 13 polymer

Polymer

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Entity 14 polymer

Polymer

Entity 15 polymer

Polymer

Entity 16 polymer

Polymer

Entity 17 polymer

Polymer

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Entity 18 polymer

Polymer

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Entity 19 polymer

Polymer

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Entity 20 polymer

Polymer

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Entity 21 polymer

Polymer

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Entity 22 polymer

Polymer

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Entity 23 polymer

Polymer

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Entity 24 polymer

Polymer

Source

Entity 25 polymer

Polymer

Source

Entity 26 polymer

Polymer

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Entity 27 polymer

Polymer

Source

Entity 28 polymer

Polymer