Current Protein Identity:P03437 New Search
Main Difference Dimensions in This Set
Different construct Different mutation/modification Different assembly state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
1EO8 INFLUENZA VIRUS HEMAGGLUTININ COMPLEXED WITH A NEUTRALIZING ANTIBODY Deposited 2000-03-22 Assembly 1 Other combination Heteromer;Protein × 12 PDB declaration: dodecameric(12) Consistent with protein count
Chain A 17–344(328 aa) Fragment:BROMELAIN RELEASED FRAGMENT
Chain B 346–520(175 aa) Fragment:BROMELAIN RELEASED FRAGMENT
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 6 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 6;293 K;28%(w:v) PEG 600, 100 mM Sodium Phosphate, 150 mM NaCl, 0.05% NaN3 , pH 6.0, VAPOR DIFFUSION, HANGING DROP, temperature 293K
Resolution 2.80 Å R-free 0.298
1FYT CRYSTAL STRUCTURE OF A COMPLEX OF A HUMAN ALPHA/BETA-T CELL RECEPTOR, INFLUENZA HA ANTIGEN PEPTIDE, AND MHC CLASS II MOLECULE, HLA-DR1 Deposited 2000-10-03 Assembly 1 Protein heterocomplex Heteromer;Protein × 5 PDB declaration: pentameric(5) Consistent with protein count
Chain C 322–334(13 aa) Fragment:ANTIGEN PEPTIDE
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7;291 K;11% PEG 8000, 1 M NaCl, 100 mM HEPES, pH 7.0, VAPOR DIFFUSION, SITTING DROP, temperature 18K
Resolution 2.60 Å R-free 0.255
1HA0 HEMAGGLUTININ PRECURSOR HA0 Deposited 1998-10-08 Assembly 1 Other combination Homooligomer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count
Chain A 25–518(494 aa) Fragment:HA1, HA2
Mutation:R329Q NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 6 X-RAY DIFFRACTION
X-ray crystallization conditions pH 7.5;pH 7.50
Resolution 2.80 Å R-free 0.302
1HGD BINDING OF INFLUENZA VIRUS HEMAGGLUTININ TO ANALOGS OF ITS CELL-SURFACE RECEPTOR, SIALIC ACID: ANALYSIS BY PROTON NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY AND X-RAY CRYSTALLOGRAPHY Deposited 1991-11-01 Assembly 1 Other combination Homooligomer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count
Chain A 17–344(328 aa)
Chain B 346–520(175 aa)
Chain C 17–344(328 aa)
Chain D 346–520(175 aa)
Chain E 17–344(328 aa)
Chain F 346–520(175 aa)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 12 X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 2.70 Å
1HGE BINDING OF INFLUENZA VIRUS HEMAGGLUTININ TO ANALOGS OF ITS CELL-SURFACE RECEPTOR, SIALIC ACID: ANALYSIS BY PROTON NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY AND X-RAY CRYSTALLOGRAPHY Deposited 1991-11-01 Assembly 1 Other combination Homooligomer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count
Chain A 17–344(328 aa)
Chain B 346–520(175 aa)
Chain C 17–344(328 aa)
Chain D 346–520(175 aa)
Chain E 17–344(328 aa)
Chain F 346–520(175 aa)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 12 MNA 2-O-methyl-5-N-acetyl-alpha-D-neuraminic acid × 3 X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 2.60 Å
1HGF BINDING OF INFLUENZA VIRUS HEMAGGLUTININ TO ANALOGS OF ITS CELL-SURFACE RECEPTOR, SIALIC ACID: ANALYSIS BY PROTON NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY AND X-RAY CRYSTALLOGRAPHY Deposited 1991-11-01 Assembly 1 Other combination Homooligomer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count
Chain A 17–344(328 aa)
Chain B 346–520(175 aa)
Chain C 17–344(328 aa)
Chain D 346–520(175 aa)
Chain E 17–344(328 aa)
Chain F 346–520(175 aa)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 12 X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 3.00 Å
1HGG BINDING OF INFLUENZA VIRUS HEMAGGLUTININ TO ANALOGS OF ITS CELL-SURFACE RECEPTOR, SIALIC ACID: ANALYSIS BY PROTON NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY AND X-RAY CRYSTALLOGRAPHY Deposited 1991-11-01 Assembly 1 Other combination Homooligomer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count
Chain A 17–344(328 aa)
Chain B 346–520(175 aa)
Chain C 17–344(328 aa)
Chain D 346–520(175 aa)
Chain E 17–344(328 aa)
Chain F 346–520(175 aa)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 12 X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 2.90 Å
1HGH BINDING OF INFLUENZA VIRUS HEMAGGLUTININ TO ANALOGS OF ITS CELL-SURFACE RECEPTOR, SIALIC ACID: ANALYSIS BY PROTON NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY AND X-RAY CRYSTALLOGRAPHY Deposited 1991-11-01 Assembly 1 Other combination Homooligomer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count
Chain A 17–344(328 aa)
Chain B 346–520(175 aa)
Chain C 17–344(328 aa)
Chain D 346–520(175 aa)
Chain E 17–344(328 aa)
Chain F 346–520(175 aa)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 12 MNA 2-O-methyl-5-N-acetyl-alpha-D-neuraminic acid × 6 X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 2.70 Å
1HGI BINDING OF INFLUENZA VIRUS HEMAGGLUTININ TO ANALOGS OF ITS CELL-SURFACE RECEPTOR, SIALIC ACID: ANALYSIS BY PROTON NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY AND X-RAY CRYSTALLOGRAPHY Deposited 1991-11-01 Assembly 1 Other combination Homooligomer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count
Chain A 17–344(328 aa)
Chain B 346–520(175 aa)
Chain C 17–344(328 aa)
Chain D 346–520(175 aa)
Chain E 17–344(328 aa)
Chain F 346–520(175 aa)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 12 ANA methyl 4-O-acetyl-5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosidonic acid × 3 X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 2.70 Å
1HGJ BINDING OF INFLUENZA VIRUS HEMAGGLUTININ TO ANALOGS OF ITS CELL-SURFACE RECEPTOR, SIALIC ACID: ANALYSIS BY PROTON NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY AND X-RAY CRYSTALLOGRAPHY Deposited 1991-11-01 Assembly 1 Other combination Homooligomer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count
Chain A 17–344(328 aa)
Chain B 346–520(175 aa)
Chain C 17–344(328 aa)
Chain D 346–520(175 aa)
Chain E 17–344(328 aa)
Chain F 346–520(175 aa)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 12 AMN methyl 5-acetamido-9-amino-3,5,9-trideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosidonic acid × 3 X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 2.70 Å
1HTM STRUCTURE OF INFLUENZA HAEMAGGLUTININ AT THE PH OF MEMBRANE FUSION Deposited 1994-11-02 Assembly 1 Protein homooligomer Homooligomer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count
Chain A 17–43(27 aa)
Chain B 383–520(138 aa)
Chain C 17–43(27 aa)
Chain D 383–520(138 aa)
Chain E 17–43(27 aa)
Chain F 383–520(138 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 2.50 Å R-free 0.291
1J8H Crystal Structure of a Complex of a Human alpha/beta-T cell Receptor, Influenza HA Antigen Peptide, and MHC Class II Molecule, HLA-DR4 Deposited 2001-05-21 Assembly 1 Other combination Heteromer;Protein × 5 PDB declaration: pentameric(5) Consistent with protein count
Chain C 322–334(13 aa) Fragment:Antigen Peptide
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7;291 K;13% PEG 8000, 1 M NaCl, 100 mM HEPES, pH 7.0, VAPOR DIFFUSION, SITTING DROP, temperature 291K
Resolution 2.40 Å R-free 0.246
1KEN INFLUENZA VIRUS HEMAGGLUTININ COMPLEXED WITH AN ANTIBODY THAT PREVENTS THE HEMAGGLUTININ LOW PH FUSOGENIC TRANSITION Deposited 2001-11-16 Assembly 1 Other combination Heteromer;Protein × 10 PDB declaration: decameric(10) Consistent with protein count
Chain B 346–520(175 aa) Fragment:FAB fragment of antibody
Chain D 346–520(175 aa) Fragment:FAB fragment of antibody
Chain F 346–520(175 aa) Fragment:FAB fragment of antibody
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 8;293 K;peg 20000, calcium chloride, pH 8.0, VAPOR DIFFUSION, HANGING DROP, temperature 293K
Resolution 3.50 Å R-free 0.323
1QFU INFLUENZA VIRUS HEMAGGLUTININ COMPLEXED WITH A NEUTRALIZING ANTIBODY Deposited 1999-04-14 Assembly 1 Other combination Heteromer;Protein × 12 PDB declaration: dodecameric(12) Consistent with protein count
Chain A 17–344(328 aa) Fragment:BROMELAIN DIGESTED
Chain B 346–520(175 aa) Fragment:BROMELAIN DIGESTED
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 9 X-RAY DIFFRACTION
X-ray crystallization conditions pH 7;pH 7.0
Resolution 2.80 Å R-free 0.284
1QU1 CRYSTAL STRUCTURE OF EHA2 (23-185) Deposited 1999-07-05 Assembly 1 Protein homooligomer Homooligomer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count
Chain A 376–530(155 aa)
Chain B 376–530(155 aa)
Chain C 376–530(155 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions pH 4.4;2% PEG 4000, 30-150 MM NACL, pH 4.40
Resolution 1.90 Å R-free 0.250
1QU1 CRYSTAL STRUCTURE OF EHA2 (23-185) Deposited 1999-07-05 Assembly 2 Protein homooligomer Homooligomer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count
Chain D 376–530(155 aa)
Chain E 376–530(155 aa)
Chain F 376–530(155 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions pH 4.4;2% PEG 4000, 30-150 MM NACL, pH 4.40
Resolution 1.90 Å R-free 0.250
2HMG REFINEMENT OF THE INFLUENZA VIRUS HEMAGGLUTININ BY SIMULATED ANNEALING Deposited 1989-09-11 Assembly 1 Other combination Homooligomer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count
Chain A 17–344(328 aa)
Chain B 346–520(175 aa)
Chain C 17–344(328 aa)
Chain D 346–520(175 aa)
Chain E 17–344(328 aa)
Chain F 346–520(175 aa)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 12 X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 3.00 Å
2VIR INFLUENZA VIRUS HEMAGGLUTININ COMPLEXED WITH A NEUTRALIZING ANTIBODY Deposited 1997-12-22 Assembly 1 Protein heterocomplex Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count
Chain C 44–325(282 aa) Fragment:;PROTEOLYTIC FRAGMENT "HA TOP" CONTAINING HA1 RESIDUES 28 - 328 ;
Not recorded ZN ZINC ION × 3 X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 3.25 Å R-free 0.249
2VIS INFLUENZA VIRUS HEMAGGLUTININ, (ESCAPE) MUTANT WITH THR 131 REPLACED BY ILE, COMPLEXED WITH A NEUTRALIZING ANTIBODY Deposited 1997-12-22 Assembly 1 Protein heterocomplex Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count
Chain C 44–325(282 aa) Fragment:;PROTEOLYTIC FRAGMENT "HA TOP" CONTAINING HA1 RESIDUES 28 - 328 ;
Mutation:T131I ZN ZINC ION × 3 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 1 X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 3.25 Å R-free 0.267
2VIT INFLUENZA VIRUS HEMAGGLUTININ, MUTANT WITH THR 155 REPLACED BY ILE, COMPLEXED WITH A NEUTRALIZING ANTIBODY Deposited 1997-12-22 Assembly 1 Protein heterocomplex Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count
Chain C 44–325(282 aa) Fragment:;PROTEOLYTIC FRAGMENT "HA TOP" CONTAINING HA1 RESIDUES 28 - 328 ;
Mutation:T155I ZN ZINC ION × 3 X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 3.25 Å R-free 0.237
2VIU INFLUENZA VIRUS HEMAGGLUTININ Deposited 1997-12-22 Assembly 1 Other combination Homooligomer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count
Chain A 17–344(328 aa)
Chain B 346–520(175 aa)
Mutation:CHAIN A, T131I Mutation:CHAIN A, T131I NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 15 X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 2.50 Å R-free 0.242
2YPG Haemagglutinin of 1968 Human H3N2 Virus in Complex with Human Receptor Analogue LSTc Deposited 2012-10-30 Assembly 1 Other combination Homooligomer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count
Chain A 17–344(328 aa)
Chain B 346–520(175 aa) Fragment:HA2 OF BROMELAIN RELEASED ECTODOMAIN, RESIDUES 346-520
Chain C 17–344(328 aa)
Chain D 346–520(175 aa) Fragment:HA2 OF BROMELAIN RELEASED ECTODOMAIN, RESIDUES 346-520
Chain E 17–344(328 aa)
Chain F 346–520(175 aa) Fragment:HA2 OF BROMELAIN RELEASED ECTODOMAIN, RESIDUES 346-520
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 5 FLC CITRATE ANION × 13 X-RAY DIFFRACTION
X-ray crystallization conditions 1.7-2 M TRIAMMONIUM CITRATE PH 6.5
Resolution 2.85 Å R-free 0.190
3EYM Structure of Influenza Haemagglutinin in complex with an inhibitor of membrane fusion Deposited 2008-10-21 Assembly 1 Protein homooligomer Homooligomer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count
Chain A 25–345(321 aa)
Chain B 346–517(172 aa)
Chain C 25–345(321 aa)
Chain D 346–517(172 aa)
Chain E 25–345(321 aa)
Chain F 346–517(172 aa)
Not recorded EYK 2-tert-butylbenzene-1,4-diol × 3 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 8;293 K;Ammonium citratre, pH 8.0, VAPOR DIFFUSION, HANGING DROP, temperature 293K
Resolution 2.80 Å R-free 0.217
3HMG REFINEMENT OF THE INFLUENZA VIRUS HEMAGGLUTININ BY SIMULATED ANNEALING Deposited 1989-09-11 Assembly 1 Other combination Homooligomer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count
Chain A 17–344(328 aa)
Chain B 346–520(175 aa)
Chain C 17–344(328 aa)
Chain D 346–520(175 aa)
Chain E 17–344(328 aa)
Chain F 346–520(175 aa)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 12 X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 2.90 Å
3VUN Crystal structure of a influenza A virus (A/Aichi/2/1968 H3N2) hemagglutinin in C2 space group. Deposited 2012-07-02 Assembly 1 Other combination Homooligomer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count
Chain A 17–345(329 aa)
Chain B 346–520(175 aa)
Chain C 17–345(329 aa)
Chain D 346–520(175 aa)
Chain E 17–345(329 aa)
Chain F 346–520(175 aa)
Mutation:G144S, I182V Mutation:E132D Mutation:G144S, I182V Mutation:E132D Mutation:G144S, I182V Mutation:E132D NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 6 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 7.25;293 K;0.2M imidazole (pH 7.0), 27% Jeffamine ED-2001 (pH 7.0), VAPOR DIFFUSION, HANGING DROP, temperature 293K
Resolution 3.00 Å R-free 0.275
3ZTJ Structure of influenza A neutralizing antibody selected from cultures of single human plasma cells in complex with human H3 Influenza haemagglutinin. Deposited 2011-07-08 Assembly 1 Other combination Heteromer;Protein × 12 PDB declaration: dodecameric(12) Consistent with protein count
Chain A 17–345(329 aa)
Chain B 346–520(175 aa) Fragment:RESIDUES 346-520
Chain C 17–345(329 aa)
Chain D 346–520(175 aa) Fragment:RESIDUES 346-520
Chain E 17–345(329 aa)
Chain F 346–520(175 aa) Fragment:RESIDUES 346-520
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 1 X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 3.41 Å R-free 0.284
4HMG REFINEMENT OF THE INFLUENZA VIRUS HEMAGGLUTININ BY SIMULATED ANNEALING Deposited 1989-09-11 Assembly 1 Other combination Homooligomer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count
Chain A 17–344(328 aa)
Chain B 346–520(175 aa)
Chain C 17–344(328 aa)
Chain D 346–520(175 aa)
Chain E 17–344(328 aa)
Chain F 346–520(175 aa)
Not recorded SIA N-acetyl-alpha-neuraminic acid × 3 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 12 X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 3.00 Å
5HMG REFINEMENT OF THE INFLUENZA VIRUS HEMAGGLUTININ BY SIMULATED ANNEALING Deposited 1989-09-11 Assembly 1 Other combination Homooligomer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count
Chain A 17–344(328 aa)
Chain B 346–520(175 aa)
Chain C 17–344(328 aa)
Chain D 346–520(175 aa)
Chain E 17–344(328 aa)
Chain F 346–520(175 aa)
Not recorded SIA N-acetyl-alpha-neuraminic acid × 3 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 12 X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 3.20 Å
5Y2L Crystal structure of a group 2 HA binding antibody AF4H1K1 Fab in complex with the 1968 H3N2 pandemic (H3-AC/68) hemagglutinin Deposited 2017-07-26 Assembly 1 Other combination Heteromer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count
Chain A 17–345(329 aa)
Chain B 346–521(176 aa) Fragment:UNP residues 346-521
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7.5;291 K;0.19 mM CYMAL7, 0.1M HEPES pH 7.5, 40% ployethylene glycol 400
Resolution 2.90 Å R-free 0.244
6E56 Human antibody H2214 in complex with influenza hemagglutinin A/Aichi/2/1968 (X-31) (H3N2) Deposited 2018-07-19 Assembly 1 Other combination Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count
Chain D 53–335(283 aa) Fragment:head domain (UNP residues 53-335)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 1 ACT ACETATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 5;291.15 K;100 mM sodium chloride, 100 mM sodium acetate, pH 5.0, 20% w/v PEG2000 MME
Resolution 2.00 Å R-free 0.214
6E56 Human antibody H2214 in complex with influenza hemagglutinin A/Aichi/2/1968 (X-31) (H3N2) Deposited 2018-07-19 Assembly 2 Protein heterocomplex Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count
Chain A 53–335(283 aa) Fragment:head domain (UNP residues 53-335)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 1 ACT ACETATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 5;291.15 K;100 mM sodium chloride, 100 mM sodium acetate, pH 5.0, 20% w/v PEG2000 MME
Resolution 2.00 Å R-free 0.214
6N5D Broadly protective antibodies directed to a subdominant influenza hemagglutinin epitope Deposited 2018-11-21 Assembly 1 Protein heterocomplex Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count
Chain A 53–334(282 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 6.5;291 K;0.2 M sodium bromide, 0.1 M Bis-Tris propane, pH 6.5, 20% w/v PEG3350
Resolution 3.00 Å R-free 0.244
6N5D Broadly protective antibodies directed to a subdominant influenza hemagglutinin epitope Deposited 2018-11-21 Assembly 2 Protein heterocomplex Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count
Chain B 53–334(282 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 6.5;291 K;0.2 M sodium bromide, 0.1 M Bis-Tris propane, pH 6.5, 20% w/v PEG3350
Resolution 3.00 Å R-free 0.244
6N5D Broadly protective antibodies directed to a subdominant influenza hemagglutinin epitope Deposited 2018-11-21 Assembly 3 Protein heterocomplex Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count
Chain K 53–334(282 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 6.5;291 K;0.2 M sodium bromide, 0.1 M Bis-Tris propane, pH 6.5, 20% w/v PEG3350
Resolution 3.00 Å R-free 0.244
6N5E Broadly protective antibodies directed to a subdominant influenza hemagglutinin epitope Deposited 2018-11-21 Assembly 1 Other combination Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count
Chain A 53–334(282 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 6.5;291 K;0.2 M ammonium sulfate, 0.1 M MES, pH 6.5, 20% w/v PEG8000
Resolution 3.00 Å R-free 0.287
6N5E Broadly protective antibodies directed to a subdominant influenza hemagglutinin epitope Deposited 2018-11-21 Assembly 2 Other combination Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count
Chain B 53–334(282 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 6.5;291 K;0.2 M ammonium sulfate, 0.1 M MES, pH 6.5, 20% w/v PEG8000
Resolution 3.00 Å R-free 0.287
6N5E Broadly protective antibodies directed to a subdominant influenza hemagglutinin epitope Deposited 2018-11-21 Assembly 3 Other combination Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count
Chain C 53–334(282 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 6.5;291 K;0.2 M ammonium sulfate, 0.1 M MES, pH 6.5, 20% w/v PEG8000
Resolution 3.00 Å R-free 0.287
6XPX Human antibody S1V2-51 in complex with the influenza hemagglutinin head domain of A/Aichi/2/1968 (X-31)(H3N2) Deposited 2020-07-09 Assembly 1 Other combination Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count
Chain A 53–335(283 aa)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 BCN BICINE × 2 GOL GLYCEROL × 7 1PE PENTAETHYLENE GLYCOL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 9;291.15 K;0.3 M Magnesium chloride, 25% (w/v) PEG 2000, 15% (w/v) Glycerol, 0.1 M BICINE, pH 9.0
Resolution 2.60 Å R-free 0.215
6Y5G Ectodomain of X-31 Haemagglutinin at pH 8 Deposited 2020-02-25 Assembly 1 Other combination Homooligomer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count
Chain A 24–341(318 aa)
Chain B 346–517(172 aa)
Chain C 24–341(318 aa)
Chain D 346–517(172 aa)
Chain E 24–341(318 aa)
Chain F 346–517(172 aa)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 9 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.00 Å
6Y5H Ectodomain of X-31 Haemagglutinin at pH 5 (State I) Deposited 2020-02-25 Assembly 1 Other combination Homooligomer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count
Chain A 24–341(318 aa)
Chain B 346–517(172 aa)
Chain C 24–341(318 aa)
Chain D 346–517(172 aa)
Chain E 24–341(318 aa)
Chain F 346–517(172 aa)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 6 ELECTRON MICROSCOPY
cryo-EM buffer pH 5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.00 Å
6Y5I Dilated form 1 of X-31 Influenza Haemagglutinin at pH 5 (State II) Deposited 2020-02-25 Assembly 1 Other combination Homooligomer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count
Chain A 24–341(318 aa)
Chain B 346–517(172 aa)
Chain C 24–341(318 aa)
Chain D 346–517(172 aa)
Chain E 24–341(318 aa)
Chain F 346–517(172 aa)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 6 ELECTRON MICROSCOPY
cryo-EM buffer pH 5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 5.50 Å
6Y5J Dilated form 2 of X-31 Influenza Haemagglutinin at pH 5 (State III) Deposited 2020-02-25 Assembly 1 Other combination Homooligomer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count
Chain A 24–341(318 aa)
Chain B 346–517(172 aa)
Chain C 24–341(318 aa)
Chain D 346–517(172 aa)
Chain E 24–341(318 aa)
Chain F 346–517(172 aa)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 6 ELECTRON MICROSCOPY
cryo-EM buffer pH 5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 5.60 Å
6Y5K Extended Intermediate form of X-31 Influenza Haemagglutinin at pH 5 (State IV) Deposited 2020-02-25 Assembly 1 Protein homooligomer Homooligomer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count
Chain A 24–341(318 aa)
Chain B 346–517(172 aa)
Chain C 24–341(318 aa)
Chain D 346–517(172 aa)
Chain E 24–341(318 aa)
Chain F 346–517(172 aa)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 6 ELECTRON MICROSCOPY
cryo-EM buffer pH 5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.20 Å
6Y5L Signal Subtracted Extended Intermediate form of X-31 Influenza Haemagglutinin at pH 5 (State IV) Deposited 2020-02-25 Assembly 1 Insufficient information Heteromer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count
Chain B 346–517(172 aa)
Chain D 346–517(172 aa)
Chain F 346–517(172 aa)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 3 ELECTRON MICROSCOPY
cryo-EM buffer pH 5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.60 Å
7ZJ6 X-31 Hemagglutinin Precursor HA0 at pH 7.5 Deposited 2022-04-08 Assembly 1 Insufficient information Homooligomer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count
Chain A 17–520(504 aa)
Chain B 17–520(504 aa)
Chain C 17–520(504 aa)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 6 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE;4s blot
Resolution 2.60 Å
7ZJ7 X-31 Hemagglutinin Precursor HA0 at pH 4.8 Deposited 2022-04-08 Assembly 1 Insufficient information Homooligomer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count
Chain A 17–520(504 aa)
Chain B 17–520(504 aa)
Chain C 17–520(504 aa)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 3 ELECTRON MICROSCOPY
cryo-EM buffer pH 4.8
cryo-EM vitrification conditions Cryogen ETHANE;4s blot
Resolution 3.95 Å
7ZJ8 X-31 Hemagglutinin Precursor HA0 at pH 7.5 after reneutralization Deposited 2022-04-08 Assembly 1 Insufficient information Homooligomer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count
Chain A 17–520(504 aa)
Chain B 17–520(504 aa)
Chain C 17–520(504 aa)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 6 BOG octyl beta-D-glucopyranoside × 3 ELECTRON MICROSCOPY
cryo-EM buffer pH 7
cryo-EM vitrification conditions Cryogen ETHANE;4s blot
Resolution 3.10 Å
8G5B Influenza A H3N2 X-31 Hemagglutinin in complex with FL-1061 Deposited 2023-02-12 Assembly 1 Protein heterocomplex Heteromer;Protein × 7 PDB declaration: heptameric(7) Consistent with protein count
Chain A 53–335(283 aa) Fragment:head fragment
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.10 Å
8PK3 CryoEM reconstruction of hemagglutinin HK68 of Influenza A virus bound to an Affimer reagent Deposited 2023-06-24 Assembly 1 Other combination Heteromer;Protein × 9 PDB declaration: nonameric(9) Consistent with protein count
Chain D 346–520(175 aa)
Chain E 346–520(175 aa)
Chain F 346–520(175 aa)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 6 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.40 Å