当前蛋白身份：Q15070
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差异标签只比较当前检索结果；所有PDB和assembly原始记录仍分别保留。
相关结构差异明细
一行代表一个 PDB 条目中的一个 biological assembly；同一蛋白的多个单体会分别列出。
| PDB 条目 | Assembly / 聚集状态 | 构建体 | 突变与修饰 | 配体、离子与非聚合物 | 实验方法 | 实验环境 | 结构质量 |
|---|---|---|---|---|---|---|---|
| 6ZM5 Human mitochondrial ribosome in complex with OXA1L, mRNA, A/A tRNA, P/P tRNA and nascent polypeptide 提交 2020-07-01 | Assembly 1 蛋白–RNA 异源复合物；蛋白 × 88 PDB 声明：94-meric（94） 与全部聚合物一致 |
链 u
1–435（435 aa）
|
未记录 | MG MAGNESIUM ION × 189 K POTASSIUM ION × 44 ZN ZINC ION × 3 FES FE2/S2 (INORGANIC) CLUSTER × 3 ATP ADENOSINE-5'-TRIPHOSPHATE × 1 GTP GUANOSINE-5'-TRIPHOSPHATE × 1 ALA ALANINE × 1 | ELECTRON MICROSCOPY |
cryo-EM缓冲液
pH 7.5
cryo-EM玻璃化条件
冷冻剂 ETHANE
|
分辨率 2.89 Å |
| 7A5K Structure of the human mitoribosome in the post translocation state bound to mtEF-G1 提交 2020-08-21 | Assembly 1 蛋白–RNA 异源复合物；蛋白 × 86 PDB 声明：93-meric（93） 与全部聚合物一致 |
链 A5
1–435（435 aa）
|
未记录 | GCP PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER × 1 MG MAGNESIUM ION × 128 SPD SPERMIDINE × 1 ZN ZINC ION × 7 GDP GUANOSINE-5'-DIPHOSPHATE × 1 | ELECTRON MICROSCOPY |
cryo-EM缓冲液
pH 7.4
cryo-EM玻璃化条件
冷冻剂 ETHANE
|
分辨率 3.70 Å |
| 9OLF Membrane-associated human mitoribosome in complex with TACO1 提交 2025-05-12 | Assembly 1 蛋白–RNA 异源复合物；蛋白 × 93 PDB 声明：100-meric（100） 与全部聚合物一致 |
链 OX
1–435（435 aa）
|
未记录 | ZN ZINC ION × 3 SPD SPERMIDINE × 7 MG MAGNESIUM ION × 205 PUT 1,4-DIAMINOBUTANE × 1 K POTASSIUM ION × 54 SPM SPERMINE × 2 NAD NICOTINAMIDE-ADENINE-DINUCLEOTIDE × 1 FES FE2/S2 (INORGANIC) CLUSTER × 3 GDP GUANOSINE-5'-DIPHOSPHATE × 1 ATP ADENOSINE-5'-TRIPHOSPHATE × 1 VAL VALINE × 1 | ELECTRON MICROSCOPY |
cryo-EM缓冲液
pH 7.4
cryo-EM玻璃化条件
冷冻剂 ETHANE
|
分辨率 2.46 Å |
| 9PG8 In situ structure of the human mitoribosome in the P-E state 提交 2025-07-07 | Assembly 1 蛋白–RNA 异源复合物；蛋白 × 86 PDB 声明：93-meric（93） 与全部聚合物一致 |
链 OX
1–435（435 aa）
|
未记录 | ZN ZINC ION × 3 K POTASSIUM ION × 54 SPD SPERMIDINE × 8 PUT 1,4-DIAMINOBUTANE × 1 MG MAGNESIUM ION × 205 VAL VALINE × 1 FES FE2/S2 (INORGANIC) CLUSTER × 3 NAD NICOTINAMIDE-ADENINE-DINUCLEOTIDE × 1 SPM SPERMINE × 3 ATP ADENOSINE-5'-TRIPHOSPHATE × 1 GDP GUANOSINE-5'-DIPHOSPHATE × 1 | ELECTRON MICROSCOPY |
cryo-EM缓冲液
pH 7.4
cryo-EM玻璃化条件
冷冻剂 ETHANE
|
分辨率 3.06 Å |
| 9PGF In situ structure of the human mitoribosome in the P state 提交 2025-07-07 | Assembly 1 蛋白–RNA 异源复合物；蛋白 × 86 PDB 声明：91-meric（91） 与全部聚合物一致 |
链 OX
1–435（435 aa）
|
未记录 | ZN ZINC ION × 3 K POTASSIUM ION × 54 SPD SPERMIDINE × 8 PUT 1,4-DIAMINOBUTANE × 1 MG MAGNESIUM ION × 205 VAL VALINE × 1 FES FE2/S2 (INORGANIC) CLUSTER × 3 NAD NICOTINAMIDE-ADENINE-DINUCLEOTIDE × 1 SPM SPERMINE × 3 ATP ADENOSINE-5'-TRIPHOSPHATE × 1 GDP GUANOSINE-5'-DIPHOSPHATE × 1 | ELECTRON MICROSCOPY |
cryo-EM缓冲液
pH 7.4
cryo-EM玻璃化条件
冷冻剂 ETHANE
|
分辨率 2.93 Å |
| 9PGI In situ structure of the human mitoribosome in the A-P-E state with TACO1 提交 2025-07-07 | Assembly 1 蛋白–RNA 异源复合物；蛋白 × 87 PDB 声明：94-meric（94） 与全部聚合物一致 |
链 OX
1–435（435 aa）
|
未记录 | ZN ZINC ION × 3 K POTASSIUM ION × 54 SPD SPERMIDINE × 7 PUT 1,4-DIAMINOBUTANE × 1 MG MAGNESIUM ION × 204 FES FE2/S2 (INORGANIC) CLUSTER × 3 NAD NICOTINAMIDE-ADENINE-DINUCLEOTIDE × 1 SPM SPERMINE × 2 ATP ADENOSINE-5'-TRIPHOSPHATE × 1 GDP GUANOSINE-5'-DIPHOSPHATE × 1 VAL VALINE × 1 | ELECTRON MICROSCOPY |
cryo-EM缓冲液
pH 7.4
cryo-EM玻璃化条件
冷冻剂 ETHANE
|
分辨率 3.02 Å |
| 9PGL In situ structure of the human mitoribosome in the A-P state with TACO1 提交 2025-07-08 | Assembly 1 蛋白–RNA 异源复合物；蛋白 × 86 PDB 声明：92-meric（92） 与全部聚合物一致 |
链 OX
1–435（435 aa）
|
未记录 | ZN ZINC ION × 3 K POTASSIUM ION × 54 SPD SPERMIDINE × 8 PUT 1,4-DIAMINOBUTANE × 1 MG MAGNESIUM ION × 204 FES FE2/S2 (INORGANIC) CLUSTER × 3 NAD NICOTINAMIDE-ADENINE-DINUCLEOTIDE × 1 SPM SPERMINE × 2 ATP ADENOSINE-5'-TRIPHOSPHATE × 1 GDP GUANOSINE-5'-DIPHOSPHATE × 1 VAL VALINE × 1 | ELECTRON MICROSCOPY |
cryo-EM缓冲液
pH 7.4
cryo-EM玻璃化条件
冷冻剂 ETHANE
|
分辨率 2.90 Å |
| 9PGM In situ structure of the human mitoribosome in the P-E state from TACO1-knockout cells 提交 2025-07-08 | Assembly 1 蛋白–RNA 异源复合物；蛋白 × 85 PDB 声明：91-meric（91） 与全部聚合物一致 |
链 OX
1–435（435 aa）
|
未记录 | ZN ZINC ION × 3 K POTASSIUM ION × 54 SPD SPERMIDINE × 7 PUT 1,4-DIAMINOBUTANE × 1 MG MAGNESIUM ION × 204 FES FE2/S2 (INORGANIC) CLUSTER × 3 NAD NICOTINAMIDE-ADENINE-DINUCLEOTIDE × 1 SPM SPERMINE × 2 ATP ADENOSINE-5'-TRIPHOSPHATE × 1 GDP GUANOSINE-5'-DIPHOSPHATE × 1 VAL VALINE × 1 | ELECTRON MICROSCOPY |
cryo-EM缓冲液
pH 7.4
cryo-EM玻璃化条件
冷冻剂 ETHANE
|
分辨率 3.18 Å |
| 9PR4 In Situ Structure of the Human Mitochondrial Large Subunit 39S in Complex with TACO1 提交 2025-07-23 | Assembly 1 蛋白–RNA 异源复合物；蛋白 × 61 PDB 声明：63-meric（63） 与全部聚合物一致 |
链 OX
1–435（435 aa）
|
未记录 | ZN ZINC ION × 2 K POTASSIUM ION × 36 MG MAGNESIUM ION × 141 FES FE2/S2 (INORGANIC) CLUSTER × 1 SPD SPERMIDINE × 2 PUT 1,4-DIAMINOBUTANE × 1 VAL VALINE × 1 | ELECTRON MICROSCOPY |
cryo-EM缓冲液
pH 7.4
cryo-EM玻璃化条件
冷冻剂 ETHANE
|
分辨率 2.77 Å |
| 9PRA In Situ Structure of the Human Mitoribosome Large Subunit 39S in Complex with EF-Tu 提交 2025-07-23 | Assembly 1 蛋白–RNA 异源复合物；蛋白 × 64 PDB 声明：66-meric（66） 与全部聚合物一致 |
链 OX
1–435（435 aa）
|
未记录 | ZN ZINC ION × 2 K POTASSIUM ION × 36 MG MAGNESIUM ION × 141 FES FE2/S2 (INORGANIC) CLUSTER × 1 SPD SPERMIDINE × 2 PUT 1,4-DIAMINOBUTANE × 1 VAL VALINE × 1 | ELECTRON MICROSCOPY |
cryo-EM缓冲液
pH 7.4
cryo-EM玻璃化条件
冷冻剂 ETHANE
|
分辨率 2.83 Å |
| 9PRD In situ structure of the human mitoribosome in the P state from TACO1-knockout cells 提交 2025-07-23 | Assembly 1 蛋白–RNA 异源复合物；蛋白 × 84 PDB 声明：89-meric（89） 与全部聚合物一致 |
链 OX
1–435（435 aa）
|
未记录 | ZN ZINC ION × 3 K POTASSIUM ION × 54 SPD SPERMIDINE × 7 PUT 1,4-DIAMINOBUTANE × 1 MG MAGNESIUM ION × 204 FES FE2/S2 (INORGANIC) CLUSTER × 3 NAD NICOTINAMIDE-ADENINE-DINUCLEOTIDE × 1 SPM SPERMINE × 2 ATP ADENOSINE-5'-TRIPHOSPHATE × 1 GDP GUANOSINE-5'-DIPHOSPHATE × 1 VAL VALINE × 1 | ELECTRON MICROSCOPY |
cryo-EM缓冲液
pH 7.4
cryo-EM玻璃化条件
冷冻剂 ETHANE
|
分辨率 3.31 Å |
| 9PRQ In situ structure of human mitoribosome in the A/T-P state from TACO1-knockout cells 提交 2025-07-24 | Assembly 1 蛋白–RNA 异源复合物；蛋白 × 85 PDB 声明：91-meric（91） 与全部聚合物一致 |
链 OX
1–435（435 aa）
|
未记录 | ZN ZINC ION × 3 K POTASSIUM ION × 54 SPD SPERMIDINE × 7 PUT 1,4-DIAMINOBUTANE × 1 MG MAGNESIUM ION × 204 FES FE2/S2 (INORGANIC) CLUSTER × 3 NAD NICOTINAMIDE-ADENINE-DINUCLEOTIDE × 1 SPM SPERMINE × 2 ATP ADENOSINE-5'-TRIPHOSPHATE × 1 GDP GUANOSINE-5'-DIPHOSPHATE × 1 VAL VALINE × 1 | ELECTRON MICROSCOPY |
cryo-EM缓冲液
pH 7.4
cryo-EM玻璃化条件
冷冻剂 ETHANE
|
分辨率 3.34 Å |
| 9PRX In situ structure of the human mitoribosome in the A-P state from TACO1-knockout cells 提交 2025-07-24 | Assembly 1 蛋白–RNA 异源复合物；蛋白 × 84 PDB 声明：90-meric（90） 与全部聚合物一致 |
链 OX
1–435（435 aa）
|
未记录 | VAL VALINE × 1 ZN ZINC ION × 3 K POTASSIUM ION × 54 SPD SPERMIDINE × 7 PUT 1,4-DIAMINOBUTANE × 1 MG MAGNESIUM ION × 204 FES FE2/S2 (INORGANIC) CLUSTER × 3 NAD NICOTINAMIDE-ADENINE-DINUCLEOTIDE × 1 SPM SPERMINE × 2 ATP ADENOSINE-5'-TRIPHOSPHATE × 1 GDP GUANOSINE-5'-DIPHOSPHATE × 1 | ELECTRON MICROSCOPY |
cryo-EM缓冲液
pH 7.4
cryo-EM玻璃化条件
冷冻剂 ETHANE
|
分辨率 3.23 Å |
| 9PS0 In situ structure of the human mitoribosome in the A/P-P/E state from TACO1-knockout cells 提交 2025-07-24 | Assembly 1 蛋白–RNA 异源复合物；蛋白 × 85 PDB 声明：91-meric（91） 与全部聚合物一致 |
链 OX
1–435（435 aa）
|
未记录 | ZN ZINC ION × 3 K POTASSIUM ION × 52 SPD SPERMIDINE × 7 PUT 1,4-DIAMINOBUTANE × 1 MG MAGNESIUM ION × 204 NAD NICOTINAMIDE-ADENINE-DINUCLEOTIDE × 1 SPM SPERMINE × 2 FES FE2/S2 (INORGANIC) CLUSTER × 3 ATP ADENOSINE-5'-TRIPHOSPHATE × 1 GDP GUANOSINE-5'-DIPHOSPHATE × 1 VAL VALINE × 1 | ELECTRON MICROSCOPY |
cryo-EM缓冲液
pH 7.4
cryo-EM玻璃化条件
冷冻剂 ETHANE
|
分辨率 3.29 Å |
| 9PS7 In situ structure of the human mitoribosome in the A/T-P-E state from TACO1-knockout cells 提交 2025-07-25 | Assembly 1 蛋白–RNA 异源复合物；蛋白 × 86 PDB 声明：93-meric（93） 与全部聚合物一致 |
链 OX
1–435（435 aa）
|
未记录 | ZN ZINC ION × 3 K POTASSIUM ION × 54 SPD SPERMIDINE × 7 PUT 1,4-DIAMINOBUTANE × 1 MG MAGNESIUM ION × 204 FES FE2/S2 (INORGANIC) CLUSTER × 3 NAD NICOTINAMIDE-ADENINE-DINUCLEOTIDE × 1 SPM SPERMINE × 2 ATP ADENOSINE-5'-TRIPHOSPHATE × 1 GDP GUANOSINE-5'-DIPHOSPHATE × 1 VAL VALINE × 1 | ELECTRON MICROSCOPY |
cryo-EM缓冲液
pH 7.4
cryo-EM玻璃化条件
冷冻剂 ETHANE
|
分辨率 3.08 Å |
| 9PSI In situ structure of the human mitoribosome in the A-P-E state from TACO1-knockout cells 提交 2025-07-25 | Assembly 1 蛋白–RNA 异源复合物；蛋白 × 85 PDB 声明：92-meric（92） 与全部聚合物一致 |
链 OX
1–435（435 aa）
|
未记录 | ZN ZINC ION × 3 K POTASSIUM ION × 54 SPD SPERMIDINE × 7 PUT 1,4-DIAMINOBUTANE × 1 MG MAGNESIUM ION × 204 FES FE2/S2 (INORGANIC) CLUSTER × 3 NAD NICOTINAMIDE-ADENINE-DINUCLEOTIDE × 1 SPM SPERMINE × 2 ATP ADENOSINE-5'-TRIPHOSPHATE × 1 GDP GUANOSINE-5'-DIPHOSPHATE × 1 VAL VALINE × 1 | ELECTRON MICROSCOPY |
cryo-EM缓冲液
pH 7.4
cryo-EM玻璃化条件
冷冻剂 ETHANE
|
分辨率 3.12 Å |
| 9PSM In situ structure of the human mitoribosome in the A/P-P/E state 提交 2025-07-25 | Assembly 1 蛋白–RNA 异源复合物；蛋白 × 87 PDB 声明：93-meric（93） 与全部聚合物一致 |
链 OX
1–435（435 aa）
|
未记录 | ZN ZINC ION × 3 K POTASSIUM ION × 54 SPD SPERMIDINE × 8 PUT 1,4-DIAMINOBUTANE × 1 MG MAGNESIUM ION × 204 FES FE2/S2 (INORGANIC) CLUSTER × 3 NAD NICOTINAMIDE-ADENINE-DINUCLEOTIDE × 1 SPM SPERMINE × 2 ATP ADENOSINE-5'-TRIPHOSPHATE × 1 GDP GUANOSINE-5'-DIPHOSPHATE × 1 VAL VALINE × 1 | ELECTRON MICROSCOPY |
cryo-EM缓冲液
pH 7.4
cryo-EM玻璃化条件
冷冻剂 ETHANE
|
分辨率 2.98 Å |