Current Protein Identity:Q15906
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 5FUG Crystal structure of a human YL1-H2A.Z-H2B complex Deposited 2016-01-27 | Assembly 1 Protein heterocomplex Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count |
Chain I
6–69(64 aa)
Fragment:N-TERMINAL DOMAIN
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
0.1 M SUCCINIC ACID/PHOSPHATE/GLYCINE SYSTEM PH 6/7 ; 25% PEG 1500
|
Resolution 2.70 Å R-free 0.243 |
| 5FUG Crystal structure of a human YL1-H2A.Z-H2B complex Deposited 2016-01-27 | Assembly 2 Protein heterocomplex Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count |
Chain F
6–69(64 aa)
Fragment:N-TERMINAL DOMAIN
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
0.1 M SUCCINIC ACID/PHOSPHATE/GLYCINE SYSTEM PH 6/7 ; 25% PEG 1500
|
Resolution 2.70 Å R-free 0.243 |
| 5FUG Crystal structure of a human YL1-H2A.Z-H2B complex Deposited 2016-01-27 | Assembly 3 Protein heterocomplex Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count |
Chain C
6–69(64 aa)
Fragment:N-TERMINAL DOMAIN
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
0.1 M SUCCINIC ACID/PHOSPHATE/GLYCINE SYSTEM PH 6/7 ; 25% PEG 1500
|
Resolution 2.70 Å R-free 0.243 |
| 5FUG Crystal structure of a human YL1-H2A.Z-H2B complex Deposited 2016-01-27 | Assembly 4 Protein heterocomplex Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count |
Chain L
6–69(64 aa)
Fragment:N-TERMINAL DOMAIN
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
0.1 M SUCCINIC ACID/PHOSPHATE/GLYCINE SYSTEM PH 6/7 ; 25% PEG 1500
|
Resolution 2.70 Å R-free 0.243 |
| 8QR1 Cryo-EM structure of the human Tip60 complex Deposited 2023-10-06 | Assembly 1 Protein heterocomplex Heteromer;Protein × 13 PDB declaration: 13-meric(13) Consistent with protein count |
Chain S
1–364(364 aa)
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.40 Å |
| 8X15 Structure of nucleosome-bound SRCAP-C in the apo state Deposited 2023-11-06 | Assembly 1 Protein–DNA Heteromer;Protein × 23 PDB declaration: 25-meric(25) Consistent with all polymers |
Chain J
1–364(364 aa)
|
Not recorded | ADP ADENOSINE-5'-DIPHOSPHATE × 6 ATP ADENOSINE-5'-TRIPHOSPHATE × 2 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.20 Å |
| 8X19 Structure of nucleosome-bound SRCAP-C in the ADP-BeFx-bound state Deposited 2023-11-06 | Assembly 1 Protein–DNA Heteromer;Protein × 23 PDB declaration: 25-meric(25) Consistent with all polymers |
Chain J
1–364(364 aa)
|
Not recorded | ADP ADENOSINE-5'-DIPHOSPHATE × 7 MG MAGNESIUM ION × 1 BEF BERYLLIUM TRIFLUORIDE ION × 1 ATP ADENOSINE-5'-TRIPHOSPHATE × 2 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.20 Å |
| 8X1C Structure of nucleosome-bound SRCAP-C in the ADP-bound state Deposited 2023-11-06 | Assembly 1 Protein–DNA Heteromer;Protein × 23 PDB declaration: 25-meric(25) Consistent with all polymers |
Chain J
1–364(364 aa)
|
Not recorded | ADP ADENOSINE-5'-DIPHOSPHATE × 7 ATP ADENOSINE-5'-TRIPHOSPHATE × 3 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.20 Å |
| 8XVG Structure of human NuA4/TIP60 complex Deposited 2024-01-15 | Assembly 1 Protein heterocomplex Heteromer;Protein × 14 PDB declaration: tetradecameric(14) Consistent with protein count |
Chain N
1–364(364 aa)
|
Not recorded | IHP INOSITOL HEXAKISPHOSPHATE × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 9 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 9.40 Å |
| 8XVT The core subcomplex of human NuA4/TIP60 complex Deposited 2024-01-15 | Assembly 1 Protein heterocomplex Heteromer;Protein × 13 PDB declaration: tridecameric(13) Consistent with protein count |
Chain N
1–364(364 aa)
|
Not recorded | ADP ADENOSINE-5'-DIPHOSPHATE × 9 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.20 Å |
| 9C57 Reconstituted P400 Subcomplex of the human TIP60 complex Deposited 2024-06-05 | Assembly 1 Protein heterocomplex Heteromer;Protein × 13 PDB declaration: tridecameric(13) Consistent with protein count |
Chain K
1–364(364 aa)
|
Not recorded | AGS PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER × 7 ATP ADENOSINE-5'-TRIPHOSPHATE × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.75 Å |
| 9C62 P400 subcomplex of the native human TIP60 complex Deposited 2024-06-07 | Assembly 1 Protein heterocomplex Heteromer;Protein × 15 PDB declaration: pentadecameric(15) Consistent with protein count |
Chain K
1–364(364 aa)
|
Not recorded | ADP ADENOSINE-5'-DIPHOSPHATE × 6 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 5.28 Å |
| 9CA7 Cryo-EM structure of human SRCAP-nucleosome complex in the fully-engaged state (composite structure) Deposited 2024-06-17 | Assembly 1 Protein–DNA Heteromer;Protein × 18 PDB declaration: 20-meric(20) Consistent with all polymers |
Chain B
1–364(364 aa)
|
Not recorded | AGS PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER × 2 MG MAGNESIUM ION × 5 ZN ZINC ION × 2 ADP ADENOSINE-5'-DIPHOSPHATE × 6 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.6
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.35 Å |
| 9CA8 Cryo-EM structure of human SRCAP-nucleosome complex in the partially-engaged state (composite structure) Deposited 2024-06-17 | Assembly 1 Protein–DNA Heteromer;Protein × 18 PDB declaration: 20-meric(20) Consistent with all polymers |
Chain B
1–364(364 aa)
|
Not recorded | AGS PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER × 2 MG MAGNESIUM ION × 5 ZN ZINC ION × 2 ADP ADENOSINE-5'-DIPHOSPHATE × 6 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.6
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.92 Å |
| 9CA9 Cryo-EM structure of the human SRCAP complex in the unbound state (composite structure) Deposited 2024-06-17 | Assembly 1 Protein heterocomplex Heteromer;Protein × 10 PDB declaration: decameric(10) Consistent with protein count |
Chain B
1–364(364 aa)
|
Not recorded | AGS PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER × 1 MG MAGNESIUM ION × 4 ZN ZINC ION × 2 ADP ADENOSINE-5'-DIPHOSPHATE × 6 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.6
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.56 Å |
| 9CAA Cryo-EM structure of human SRCAP-nucleosome complex in the pre-engaged state (composite structure) Deposited 2024-06-17 | Assembly 1 Protein–DNA Heteromer;Protein × 18 PDB declaration: 20-meric(20) Consistent with all polymers |
Chain B
1–364(364 aa)
|
Not recorded | AGS PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER × 1 MG MAGNESIUM ION × 4 ZN ZINC ION × 2 ADP ADENOSINE-5'-DIPHOSPHATE × 6 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.6
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 4.04 Å |
| 9CAB Cryo-EM structure of human SRCAP-nucleosome complex in the encounter state (composite structure) Deposited 2024-06-17 | Assembly 1 Protein–DNA Heteromer;Protein × 18 PDB declaration: 20-meric(20) Consistent with all polymers |
Chain B
1–364(364 aa)
|
Not recorded | AGS PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER × 2 MG MAGNESIUM ION × 5 ZN ZINC ION × 2 ADP ADENOSINE-5'-DIPHOSPHATE × 6 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.6
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.94 Å |
| 9CAC Cryo-EM structure of the RuvBL lobe of the native human TIP60 complex (composite structure) Deposited 2024-06-17 | Assembly 1 Protein heterocomplex Heteromer;Protein × 13 PDB declaration: 13-meric(13) Consistent with protein count |
Chain B
1–364(364 aa)
|
Not recorded | ADP ADENOSINE-5'-DIPHOSPHATE × 7 MG MAGNESIUM ION × 8 ATP ADENOSINE-5'-TRIPHOSPHATE × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.6
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.43 Å |
| 9CAE Cryo-EM structure of the reconstituted RuvBL lobe of the human TIP60 complex (composite structure) Deposited 2024-06-17 | Assembly 1 Protein heterocomplex Heteromer;Protein × 12 PDB declaration: 12-meric(12) Consistent with protein count |
Chain B
1–364(364 aa)
|
Not recorded | AGS PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER × 8 MG MAGNESIUM ION × 8 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.6
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.07 Å |
| 9INC High resolutional Crystal Structure of human H2A.Z-H2B dimer in complex with human YL1-Z domain Deposited 2024-07-06 | Assembly 1 Protein heterocomplex Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count |
Chain C
8–73(66 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;289.15 K;45% PEG200
0.1 M HEPES pH 7.5
|
Resolution 2.01 Å R-free 0.257 |
| 9INC High resolutional Crystal Structure of human H2A.Z-H2B dimer in complex with human YL1-Z domain Deposited 2024-07-06 | Assembly 2 Protein heterocomplex Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count |
Chain F
8–73(66 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;289.15 K;45% PEG200
0.1 M HEPES pH 7.5
|
Resolution 2.01 Å R-free 0.257 |
| 9INC High resolutional Crystal Structure of human H2A.Z-H2B dimer in complex with human YL1-Z domain Deposited 2024-07-06 | Assembly 3 Protein heterocomplex Heteromer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count |
Chain C
8–73(66 aa)
Chain F
8–73(66 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;289.15 K;45% PEG200
0.1 M HEPES pH 7.5
|
Resolution 2.01 Å R-free 0.257 |