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Protein Structures and Oligomeric States

Enter a protein name, UniProt accession or PDB ID. Name searches ask you to confirm the protein identity before related structures are queried.

Current Protein Identity：Q9H165 New Search
17PDB entries
26Biological assembly
38chain/assembly records
Main Difference Dimensions in This Set
Different construct Different mutation/modification Different assembly state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
5VTB Crystal structure of RBBP4 bound to BCL11a peptide Deposited 2017-05-16 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 2–16（15 aa） Fragment：UNP residues 2-16
Not recorded GOL GLYCEROL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；293 K；25% PEG2000 MME, 0.1 M potassium thiocyanate
Resolution 2.40 Å R-free 0.244
6KI6 Crystal structure of BCL11A in complex with gamma-globin -115 HPFH region Deposited 2019-07-17 Assembly 1 Protein–DNA Monomer；Protein × 1 PDB declaration: trimeric（3） Consistent with all polymers
Chain A 731–835（105 aa）
Not recorded ZN ZINC ION × 3 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；293 K；0.2 M calcium acetate hydrate, 0.1 M sodium cacodylate trihydrate (pH6.5), 18% w/v polyethylene glycol 8,000
Resolution 2.50 Å R-free 0.251
6KI6 Crystal structure of BCL11A in complex with gamma-globin -115 HPFH region Deposited 2019-07-17 Assembly 2 Protein–DNA Monomer；Protein × 1 PDB declaration: trimeric（3） Consistent with all polymers
Chain B 731–835（105 aa）
Not recorded ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；293 K；0.2 M calcium acetate hydrate, 0.1 M sodium cacodylate trihydrate (pH6.5), 18% w/v polyethylene glycol 8,000
Resolution 2.50 Å R-free 0.251
6U9Q Crystal Structure Analysis of DNA-BCL11A Znf domain complex Deposited 2019-09-09 Assembly 1 Protein–DNA Monomer；Protein × 1 PDB declaration: trimeric（3） Consistent with all polymers
Chain A 730–835（106 aa）
Not recorded ZN ZINC ION × 3 PO4 PHOSPHATE ION × 2 MG MAGNESIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；293 K；NaMalate~8.0
Resolution 1.83 Å R-free 0.195
8DTN The complex of nanobody 6101 with BCL11A ZF6 Deposited 2022-07-26 Assembly 1 Protein heterocomplex Heteromer；Protein × 8 PDB declaration: octameric（8） Consistent with protein count
Chain B 797–826（30 aa）
Chain D 797–826（30 aa）
Chain F 797–826（30 aa）
Chain H 797–826（30 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) MG MAGNESIUM ION × 4 ZN ZINC ION × 4 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；281.15 K；0.1 M Bis-Tris propane, pH 6.0-7.0, 0.2 M NaKPO4 and 18%-20% PEG 3350
Resolution 2.20 Å R-free 0.232
8DTN The complex of nanobody 6101 with BCL11A ZF6 Deposited 2022-07-26 Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 797–826（30 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) MG MAGNESIUM ION × 1 ZN ZINC ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；281.15 K；0.1 M Bis-Tris propane, pH 6.0-7.0, 0.2 M NaKPO4 and 18%-20% PEG 3350
Resolution 2.20 Å R-free 0.232
8DTN The complex of nanobody 6101 with BCL11A ZF6 Deposited 2022-07-26 Assembly 3 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain D 797–826（30 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) ZN ZINC ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；281.15 K；0.1 M Bis-Tris propane, pH 6.0-7.0, 0.2 M NaKPO4 and 18%-20% PEG 3350
Resolution 2.20 Å R-free 0.232
8DTN The complex of nanobody 6101 with BCL11A ZF6 Deposited 2022-07-26 Assembly 4 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain F 797–826（30 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) MG MAGNESIUM ION × 3 ZN ZINC ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；281.15 K；0.1 M Bis-Tris propane, pH 6.0-7.0, 0.2 M NaKPO4 and 18%-20% PEG 3350
Resolution 2.20 Å R-free 0.232
8DTN The complex of nanobody 6101 with BCL11A ZF6 Deposited 2022-07-26 Assembly 5 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain H 797–826（30 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) ZN ZINC ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；281.15 K；0.1 M Bis-Tris propane, pH 6.0-7.0, 0.2 M NaKPO4 and 18%-20% PEG 3350
Resolution 2.20 Å R-free 0.232
8DTU The complex of nanobody 5344N74D with BCL11A ZF6. Deposited 2022-07-26 Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain C 799–826（28 aa）
Not recorded ZN ZINC ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；281.15 K；0.1 M HEPES, pH 7.5-8.2, 2.2M Li2SO4.
Resolution 2.45 Å R-free 0.288
8THO Solution structure of the zinc finger repeat domain of BCL11A (ZnF456) Deposited 2023-07-17 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 737–835（99 aa） Fragment：residues 737-835
Not recorded ZN ZINC ION × 3 SOLUTION NMR
NMR measurement conditions pH 6；298 K；Ionic strength (raw mmCIF value) 163；Pressure 1
NMR sample composition 137 mM sodium chloride, 2.7 mM potassium chloride, 10 mM sodium phosphate, 1.8 mM potassium phosphate, 1 mM dithiothreitol, 90% H2O/10% D2O | 90% H2O/10% D2O
Resolution not provided
8TLO Crystal Structure Analysis of BCL11A in complex with DNA Deposited 2023-07-27 Assembly 1 Protein–DNA Monomer；Protein × 1 PDB declaration: trimeric（3） Consistent with all polymers
Chain A 730–835（106 aa）
Not recorded ZN ZINC ION × 3 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；277 K；30% PEG6K and 0.1M Na Citrate pH 5.0
Resolution 2.76 Å R-free 0.269
9B4P Tetramer Formation of the BCL11A ZF0 Domain Deposited 2024-03-21 Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain B 45–71（27 aa） Fragment：ZF0 domain
Chain C 45–71（27 aa） Fragment：ZF0 domain
Not recorded ZN ZINC ION × 4 X-RAY DIFFRACTION
X-ray crystallization conditions EVAPORATION；pH 7.3；291.15 K；0.2M potassium nitrate, 0.1M Tris-HCl pH 7.3, 20% PEG3350
Resolution 2.56 Å R-free 0.294
9B4P Tetramer Formation of the BCL11A ZF0 Domain Deposited 2024-03-21 Assembly 2 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 45–71（27 aa） Fragment：ZF0 domain
Chain D 45–71（27 aa） Fragment：ZF0 domain
Chain E 45–71（27 aa） Fragment：ZF0 domain
Chain F 45–71（27 aa） Fragment：ZF0 domain
Not recorded ZN ZINC ION × 4 X-RAY DIFFRACTION
X-ray crystallization conditions EVAPORATION；pH 7.3；291.15 K；0.2M potassium nitrate, 0.1M Tris-HCl pH 7.3, 20% PEG3350
Resolution 2.56 Å R-free 0.294
9B4P Tetramer Formation of the BCL11A ZF0 Domain Deposited 2024-03-21 Assembly 3 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain G 45–71（27 aa） Fragment：ZF0 domain
Chain H 45–71（27 aa） Fragment：ZF0 domain
Chain I 45–71（27 aa） Fragment：ZF0 domain
Chain J 45–71（27 aa） Fragment：ZF0 domain
Not recorded ZN ZINC ION × 4 X-RAY DIFFRACTION
X-ray crystallization conditions EVAPORATION；pH 7.3；291.15 K；0.2M potassium nitrate, 0.1M Tris-HCl pH 7.3, 20% PEG3350
Resolution 2.56 Å R-free 0.294
9BV0 NMR structure of the Z0 CCHC zinc-finger of transcription repressor Bcl11A Deposited 2024-05-18 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 46–72（27 aa） Fragment：B0 atypical C2HC zinc-finger domain, residues 46-72
Not recorded ZN ZINC ION × 1 SOLUTION NMR
NMR measurement conditions pH 6.3；298 K；Ionic strength (raw mmCIF value) 0.6；Pressure 1
NMR measurement conditions pH 5.8；298 K；Ionic strength (raw mmCIF value) 0.6；Pressure 1
NMR sample composition 40 uM Bcl11A-Z0, 600 uM Zn2+, 90% H2O/10% D20 | 90% H2O/10% D20
NMR sample composition 40 uM Bcl11A-Z0, 600 uM Zn2+, 100% D20 | 100% D2O
Resolution not provided
9E6R BCL11A ZF4-6 in Complex with a DNA Sequence Observed in the Human Globin Locus Containing Motif TGACCA Deposited 2024-10-30 Assembly 1 Protein–DNA Monomer；Protein × 1 PDB declaration: trimeric（3） Consistent with all polymers
Chain A 730–835（106 aa） Fragment：Zinc finger domains 4-6
Not recorded ZN ZINC ION × 4 EDO 1,2-ETHANEDIOL × 3 MG MAGNESIUM ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7.8；292 K；24 % v/v Ethanol, 0.1 M HEPES 7.8, 40 mM Magnesium chloride hexahydrate
Resolution 2.09 Å R-free 0.238
9E6R BCL11A ZF4-6 in Complex with a DNA Sequence Observed in the Human Globin Locus Containing Motif TGACCA Deposited 2024-10-30 Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain D 730–835（106 aa） Fragment：Zinc finger domains 4-6
Not recorded ZN ZINC ION × 2 EDO 1,2-ETHANEDIOL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7.8；292 K；24 % v/v Ethanol, 0.1 M HEPES 7.8, 40 mM Magnesium chloride hexahydrate
Resolution 2.09 Å R-free 0.238
9E6R BCL11A ZF4-6 in Complex with a DNA Sequence Observed in the Human Globin Locus Containing Motif TGACCA Deposited 2024-10-30 Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain Y 730–835（106 aa） Fragment：Zinc finger domains 4-6
Not recorded ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7.8；292 K；24 % v/v Ethanol, 0.1 M HEPES 7.8, 40 mM Magnesium chloride hexahydrate
Resolution 2.09 Å R-free 0.238
9E6S BCL11A ZF4-6 with K784T Mutation in Complex with a DNA Sequence Observed in the Human Globin Locus Containing Motif TGACCA Deposited 2024-10-30 Assembly 1 Protein–DNA Homooligomer；Protein × 2 PDB declaration: tetrameric（4） Consistent with all polymers
Chain A 730–835（106 aa） Fragment：Zinc finger domains 4-6
Chain D 730–835（106 aa） Fragment：Zinc finger domains 4-6
Mutation：K784T Mutation：K784T EDO 1,2-ETHANEDIOL × 1 ZN ZINC ION × 6 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 9；292 K；18 % w/v PEG 3350, 17 % v/v PEG 400, 4.8 % v/v 2-Propanol, 0.1 M CAPSO 9.0
Resolution 2.20 Å R-free 0.275
9E6T BCL11A ZF4-6 in Complex with a DNA Sequence Observed in the Human Globin Locus Containing Motif TGCCCA Deposited 2024-10-30 Assembly 1 Protein–DNA Homooligomer；Protein × 2 PDB declaration: tetrameric（4） Consistent with all polymers
Chain A 730–835（106 aa） Fragment：Zinc finger domains 4-6
Chain B 730–835（106 aa） Fragment：Zinc finger domains 4-6
Not recorded ZN ZINC ION × 6 EDO 1,2-ETHANEDIOL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7；292 K；15 % w/v PEG 1000, 30 % v/v PEG 300, 0.1 M Bis-Tris Propane 7.0
Resolution 2.78 Å R-free 0.281
9YLL BCL11A ZF4-6 in Complex with a DNA Sequence Observed in the Human Globin Locus Containing Motif TGTCCA (20-mer) Deposited 2025-10-08 Assembly 1 Protein–DNA Monomer；Protein × 1 PDB declaration: trimeric（3） Consistent with all polymers
Chain A 730–835（106 aa） Fragment：Zinc finger domains 4-6
Not recorded ZN ZINC ION × 3 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.9；292 K；20% w/v Polyethylene glycol 3,350 0.2M sodium chloride
Resolution 2.38 Å R-free 0.247
9YLM BCL11A ZF4-6 in Complex with a DNA Sequence Observed in the Human Globin Locus Containing Motif TGTCCA (12-mer) Deposited 2025-10-08 Assembly 1 Protein–DNA Monomer；Protein × 1 PDB declaration: trimeric（3） Consistent with all polymers
Chain A 730–835（106 aa） Fragment：Zinc finger domains 4-6
Not recorded ZN ZINC ION × 3 EDO 1,2-ETHANEDIOL × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 5.2；292 K；28 % w/v PEG 4000, 0.1 M Sodium citrate (pH 5.2), 0.2 M Ammonium acetate
Resolution 1.91 Å R-free 0.244
9YLN BCL11A ZF4-6 in Complex with a DNA Sequence Observed in the Human Globin Locus Containing Motif TGGCCA (12-mer) Deposited 2025-10-08 Assembly 1 Protein–DNA Monomer；Protein × 1 PDB declaration: trimeric（3） Consistent with all polymers
Chain A 730–835（106 aa） Fragment：Zinc finger domains 4-6
Not recorded ZN ZINC ION × 3 EDO 1,2-ETHANEDIOL × 3 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 5.2；292 K；28 % w/v PEG 4000, 0.1 M Sodium citrate (pH 5.2), 0.2 M Ammonium acetate
Resolution 2.15 Å R-free 0.247
9YLO BCL11A ZF2-3 in Complex with a DNA Sequence Observed in the Human Globin Locus Containing Motif TGTCCA (P21212 crystal form) Deposited 2025-10-08 Assembly 1 Protein–DNA Monomer；Protein × 1 PDB declaration: trimeric（3） Consistent with all polymers
Chain A 373–433（61 aa） Fragment：C2H2 zinc finger domains 2 and 3
Not recorded EDO 1,2-ETHANEDIOL × 2 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 8.5；292 K；10% w/v PEG 20 000, 20% v/v PEG MME 500, 60mM sodium fluoride, 60mM sodium bromide, 60mM sodium iodide, 0.1M Bicine- TRIS-base (pH 8.5)
Resolution 1.97 Å R-free 0.241
9YLP BCL11A ZF2-3 in Complex with a DNA Sequence Observed in the Human Globin Locus Containing Motif TGTCCA (C2221 Crystal Form) Deposited 2025-10-08 Assembly 1 Protein–DNA Monomer；Protein × 1 PDB declaration: trimeric（3） Consistent with all polymers
Chain A 373–433（61 aa） Fragment：C2H2 zinc finger domains 2 and 3
Not recorded ZN ZINC ION × 4 MG MAGNESIUM ION × 1 PGE TRIETHYLENE GLYCOL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.5；278 K；28 % w/v PEG 4000, 0.1 M Sodium citrate (pH 6.5), 0.1 M Magnesium acetate tetrahydrate, 0.1 M Ammonium sulfate
Resolution 2.04 Å R-free 0.245

This page presents structural evidence recorded in PDB/mmCIF.“No recorded non-water small molecule” does not prove that the experimental sample was ligand-free; experimental conditions belong to the PDB experiment, while ligands and copy counts are shown for each biological assembly.