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1e0a

Cdc42 complexed with the GTPase binding domain of p21 activated kinase

Method: SOLUTION NMR D_max: 63.8 Å Quality: REASONABLE

SAXS Profile

P(r) Distribution

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1. Structure Basics

entry_id	1e0a
deposition_date	2000-03-16
title	Cdc42 complexed with the GTPase binding domain of p21 activated kinase
keywords	SIGNALLING PROTEIN, G PROTEIN SIGNALLING SER/THR KINASE, SIGNALLING PROTEIN-KINASE COMPLEX; SIGNALLING PROTEIN/KINASE
method	SOLUTION NMR

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Download Data

SAXS curve (.dat) P(r) distribution (.pr.out) Structure (CIF)

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2. SAXS Parameters (CRYSOL)

rg_guinier	18.21 Å
rg_electron	18.05 Å
i0	3648390000.00
molecular_weight	520950.0 kDa
excluded_volume	654240 Å³
envelope_volume	67071 Å³
shell_volume	25331 Å³
envelope_diameter	74.9 Å
shell_rg	29.59 Å
envelope_rg	22.57 Å
shape_rg	18.02 Å
total_rg	18.33 Å
total_atoms	72980
n_residues	4600
n_harmonics	20
q_range	— – 0.5000 Å⁻¹
n_points	101
shell_type	directional
solvent_density	0.3340 e/Å³
contrast_shell	0.0300 e/Å³
crysol_version	4.1.3

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3. P(r) Analysis (GNOM)

dmax	63.8 Å
rg_real	18.17 Å
rg_real_error	0.54 Å
i0_real	3.6480e+09
i0_real_error	4.4030e+07
rg_reciprocal	18.18 Å
i0_reciprocal	3648000000.0000
total_estimate	0.6222
solution_quality	REASONABLE a REASONABLE solution
n_peaks	3
r_peak_primary	21.6 Å
skewness	0.302
kurtosis	-0.227
angular_range	— – 0.4350 Å⁻¹
current_alpha	0.0000
highest_alpha	1539000.0000
n_real_points	75
gnom_version	4.1.3
quality_criteria	AN1: 0.000; Oscil: 0.703; Stabil: 0.998; Sysdev: 0.330; Positv: 1.000; Valcen: 0.991; Smooth: 0.000

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4. Crystallography & Experiment

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5. Entities & Polymer Info (5)

Entity 1 polymer

description	Cell division control protein 42 homolog
formula_weight	20438.6 kDa
ec_number	3.6.5.2
mutation	YES
src_method	man
entity_count	1

Polymer

type	polypeptide(L)
strand_id	A
atom_count	73100

MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGLEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLRDDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEPPEPKK

Source

organism	Homo sapiens
common_name	Human
ncbi_taxonomy_id	9606
host_organism	ESCHERICHIA COLI

Entity 2 polymer

description	Serine/threonine-protein kinase PAK 1
formula_weight	5096.6 kDa
ec_number	2.7.11.1
mutation	YES
src_method	man
entity_count	1

Polymer

type	polypeptide(L)
strand_id	B

GSISLPSDFEHTIHVGFDAVTGEFTGMPEQWARLLQTSNITKSEQK

Source

organism	Rattus norvegicus
common_name	Rat
ncbi_taxonomy_id	10116
host_organism	ESCHERICHIA COLI

Entity 3 non-polymer

description	PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
formula_weight	522.2 kDa
src_method	syn
entity_count	1

Entity 4 non-polymer

description	MAGNESIUM ION
formula_weight	24.3 kDa
src_method	syn
entity_count	1

Entity 5 water

description	water
formula_weight	18.0 kDa
src_method	nat
entity_count	2

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6. Citations (1)

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length_a	1.000 Å
length_b	1.000 Å
length_c	1.000 Å
angle_alpha	90.00 °
angle_beta	90.00 °
angle_gamma	90.00 °
z_pdb	1

space_group	P 1
int_tables_number	1
crystal_system	—

fit	/app/data/saxs_computation/e0/1e0a/1e0a.fit
pddf	/app/data/pr_computation/e0/1e0a/1e0a.pr.out
profile	/app/data/saxs_computation/e0/1e0a/1e0a.dat

Cdc42 complexed with the GTPase binding domain of p21 activated kinase

SAXS Profile

P(r) Distribution

1. Structure Basics

Download Data

2. SAXS Parameters (CRYSOL)

3. P(r) Analysis (GNOM)

4. Crystallography & Experiment

Unit Cell

Symmetry

5. Entities & Polymer Info (5)

Entity 1 polymer

Polymer

Source

Entity 2 polymer

Polymer

Source

Entity 3 non-polymer

Entity 4 non-polymer

Entity 5 water

6. Citations (1)

7. Files & Curves (10)

Files (7)

Curves (3)