5jvr

The neck-linker of Mus musculus KIF3A fused to the alpha 7 helix of Drosophila melanogaster Kinesin-1 fused to EB1

Method: X-RAY DIFFRACTION

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1. Protein Identity and Related Structures Protein Identity & Related Structures

Chimera protein of mouse KIF3A,fruit fly Kinesin-1 and human EB1

Homo sapiens

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Insufficient information	Homooligomer	Protein 2	water × 2	Consistent with protein count
2	Insufficient information	Homooligomer	Protein 2	water × 2	Consistent with protein count
3	Insufficient information	Homooligomer	Protein 2	water × 2	Consistent with protein count
4	Insufficient information	Homooligomer	Protein 2	water × 2	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	KINH_DROME
Isoform	—
PDB entities	1
Chains and sequence ranges	Author chain A； PDBConstruct 11–24； UniProt 345–358 Author chain B； PDBConstruct 11–24； UniProt 345–358 Author chain C； PDBConstruct 11–24； UniProt 345–358 Author chain D； PDBConstruct 11–24； UniProt 345–358 Author chain E； PDBConstruct 11–24； UniProt 345–358 Author chain F； PDBConstruct 11–24； UniProt 345–358 Author chain G； PDBConstruct 11–24； UniProt 345–358 Author chain H； PDBConstruct 11–24； UniProt 345–358

Chimera protein of mouse KIF3A,fruit fly Kinesin-1 and human EB1

Homo sapiens

UniProt P28741

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Insufficient information	Homooligomer	Protein 2	water × 2	Consistent with protein count
2	Insufficient information	Homooligomer	Protein 2	water × 2	Consistent with protein count
3	Insufficient information	Homooligomer	Protein 2	water × 2	Consistent with protein count
4	Insufficient information	Homooligomer	Protein 2	water × 2	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	KIF3A_MOUSE
Isoform	—
PDB entities	1
Chains and sequence ranges	Author chain A； PDBConstruct 3–10； UniProt 352–359 Author chain B； PDBConstruct 3–10； UniProt 352–359 Author chain C； PDBConstruct 3–10； UniProt 352–359 Author chain D； PDBConstruct 3–10； UniProt 352–359 Author chain E； PDBConstruct 3–10； UniProt 352–359 Author chain F； PDBConstruct 3–10； UniProt 352–359 Author chain G； PDBConstruct 3–10； UniProt 352–359 Author chain H； PDBConstruct 3–10； UniProt 352–359

Chimera protein of mouse KIF3A,fruit fly Kinesin-1 and human EB1

Homo sapiens

UniProt Q15691

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Insufficient information	Homooligomer	Protein 2	water × 2	Consistent with protein count
2	Insufficient information	Homooligomer	Protein 2	water × 2	Consistent with protein count
3	Insufficient information	Homooligomer	Protein 2	water × 2	Consistent with protein count
4	Insufficient information	Homooligomer	Protein 2	water × 2	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	MARE1_HUMAN
Isoform	—
PDB entities	1
Chains and sequence ranges	Author chain A； PDBConstruct 25–75； UniProt 207–257 Author chain B； PDBConstruct 25–75； UniProt 207–257 Author chain C； PDBConstruct 25–75； UniProt 207–257 Author chain D； PDBConstruct 25–75； UniProt 207–257 Author chain E； PDBConstruct 25–75； UniProt 207–257 Author chain F； PDBConstruct 25–75； UniProt 207–257 Author chain G； PDBConstruct 25–75； UniProt 207–257 Author chain H； PDBConstruct 25–75； UniProt 207–257

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id	5jvr
Deposition date deposition_date	2016-05-11
Structure title title	The neck-linker of Mus musculus KIF3A fused to the alpha 7 helix of Drosophila melanogaster Kinesin-1 fused to EB1
Keywords keywords	kinesin, coiled-coil, MOTOR PROTEIN; MOTOR PROTEIN
Experimental Method method	X-RAY DIFFRACTION

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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

5jvr__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

5jvr__assembly_1__model_1 | I(q)

100 plotted points; both axes use logarithmic scales.

5jvr__assembly_1__model_1 | P(r) · Pending

P(r) will be calculated and displayed separately for the same assembly/model.

Rg（Guinier）	20.29 Å
Rg (electron density)	20.01 Å
Total Rg	20.79 Å
Atom count	1069
Residues	125
Excluded volume	18985 Å³
Maximum q	0.500 Å⁻¹

Assembly	Model	Structure unit	Oligomeric description	Status	CRYSOL	Actions
1	1	`5jvr__assembly_1__model_1`	dimeric （2）	Success	4.1.3-1-20251215 (887e7ef)	View Download
2	1	`5jvr__assembly_2__model_1`	dimeric （2）	Success	4.1.3-1-20251215 (887e7ef)	View Download
3	1	`5jvr__assembly_3__model_1`	dimeric （2）	Success	4.1.3-1-20251215 (887e7ef)	View Download
4	1	`5jvr__assembly_4__model_1`	dimeric （2）	Success	4.1.3-1-20251215 (887e7ef)	View Download

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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (2)

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6. Fold Classification (SCOP + CATH) 17 domains

SCOP 2.08 (9 domains)

Domain ID domain_id	d5jvra_
Class class	a — All alpha proteins
Fold Fold fold	a.245 — EB1 dimerisation domain-like
Superfamily Superfamily superfamily	a.245.1 — EB1 dimerisation domain-like
Family Family family	a.245.1.1 — EB1 dimerisation domain-like

Domain ID domain_id	d5jvrb_
Class class	a — All alpha proteins
Fold Fold fold	a.245 — EB1 dimerisation domain-like
Superfamily Superfamily superfamily	a.245.1 — EB1 dimerisation domain-like
Family Family family	a.245.1.1 — EB1 dimerisation domain-like

Domain ID domain_id	d5jvrc_
Class class	a — All alpha proteins
Fold Fold fold	a.245 — EB1 dimerisation domain-like
Superfamily Superfamily superfamily	a.245.1 — EB1 dimerisation domain-like
Family Family family	a.245.1.1 — EB1 dimerisation domain-like

Domain ID domain_id	d5jvrd_
Class class	a — All alpha proteins
Fold Fold fold	a.245 — EB1 dimerisation domain-like
Superfamily Superfamily superfamily	a.245.1 — EB1 dimerisation domain-like
Family Family family	a.245.1.1 — EB1 dimerisation domain-like

Domain ID domain_id	d5jvre_
Class class	a — All alpha proteins
Fold Fold fold	a.245 — EB1 dimerisation domain-like
Superfamily Superfamily superfamily	a.245.1 — EB1 dimerisation domain-like
Family Family family	a.245.1.1 — EB1 dimerisation domain-like

Domain ID domain_id	d5jvrf1
Class class	a — All alpha proteins
Fold Fold fold	a.245 — EB1 dimerisation domain-like
Superfamily Superfamily superfamily	a.245.1 — EB1 dimerisation domain-like
Family Family family	a.245.1.1 — EB1 dimerisation domain-like

Domain ID domain_id	d5jvrf2
Class class	l — Artifacts
Fold Fold fold	l.1 — Tags
Superfamily Superfamily superfamily	l.1.1 — Tags
Family Family family	l.1.1.1 — Tags

Domain ID domain_id	d5jvrg_
Class class	a — All alpha proteins
Fold Fold fold	a.245 — EB1 dimerisation domain-like
Superfamily Superfamily superfamily	a.245.1 — EB1 dimerisation domain-like
Family Family family	a.245.1.1 — EB1 dimerisation domain-like

Domain ID domain_id	d5jvrh_
Class class	a — All alpha proteins
Fold Fold fold	a.245 — EB1 dimerisation domain-like
Superfamily Superfamily superfamily	a.245.1 — EB1 dimerisation domain-like
Family Family family	a.245.1.1 — EB1 dimerisation domain-like

CATH v4.4 (8 domains)

Domain ID domain_id	5jvrA00
Class class	1 — Mainly Alpha
Architecture architecture	20 — Up-down Bundle
Topology topology	5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily	1430 —

Domain ID domain_id	5jvrB00
Class class	1 — Mainly Alpha
Architecture architecture	20 — Up-down Bundle
Topology topology	5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily	1430 —

Domain ID domain_id	5jvrC00
Class class	1 — Mainly Alpha
Architecture architecture	20 — Up-down Bundle
Topology topology	5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily	1430 —

Domain ID domain_id	5jvrD00
Class class	1 — Mainly Alpha
Architecture architecture	20 — Up-down Bundle
Topology topology	5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily	1430 —

Domain ID domain_id	5jvrE00
Class class	1 — Mainly Alpha
Architecture architecture	20 — Up-down Bundle
Topology topology	5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily	1430 —

Domain ID domain_id	5jvrF00
Class class	1 — Mainly Alpha
Architecture architecture	20 — Up-down Bundle
Topology topology	5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily	1430 —

Domain ID domain_id	5jvrG00
Class class	1 — Mainly Alpha
Architecture architecture	20 — Up-down Bundle
Topology topology	5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily	1430 —

Domain ID domain_id	5jvrH00
Class class	1 — Mainly Alpha
Architecture architecture	20 — Up-down Bundle
Topology topology	5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily	1430 —

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Unit-cell length a length_a	53.172 Å
Unit-cell length b length_b	80.189 Å
Unit-cell length c length_c	155.375 Å
Unit-cell angle α angle_alpha	90.00 °
Unit-cell angle β angle_beta	90.00 °
Unit-cell angle γ angle_gamma	90.00 °
Molecules per unit cell Z z_pdb	32

Space group space_group	P 21 21 21
Space-group number int_tables_number	19
Crystal system crystal_system	—

Resolution resolution	2.100 Å
Low-resolution limit resolution_low	43.880 Å
R factor r_factor	0.1980
R_work r_work	0.1960
R_free r_free	0.2340

Description description	Chimera protein of mouse KIF3A,fruit fly Kinesin-1 and human EB1
Molecular weight formula_weight	8987.9 kDa
Source method src_method	man
Copy count entity_count	8

Polymer type type	polypeptide(L)
Chain IDs strand_id	A,B,C,D,E,F,G,H
Atom count atom_count	4801

The neck-linker of Mus musculus KIF3A fused to the alpha 7 helix of Drosophila melanogaster Kinesin-1 fused to EB1

1. Protein Identity and Related Structures Protein Identity & Related Structures

Chimera protein of mouse KIF3A,fruit fly Kinesin-1 and human EB1

State in the Current Structure

Other States of the Same Protein in the Database

Chimera protein of mouse KIF3A,fruit fly Kinesin-1 and human EB1

State in the Current Structure

Other States of the Same Protein in the Database

Chimera protein of mouse KIF3A,fruit fly Kinesin-1 and human EB1

State in the Current Structure

Other States of the Same Protein in the Database

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

5jvr__assembly_1__model_1

5jvr__assembly_1__model_1 | I(q)

5jvr__assembly_1__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

Refinement Refinement

Diffraction experiment Diffraction

5. Entities and Polymers Entities & Polymers (2)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

Entity 2 Entity 2 water

6. Fold Classification (SCOP + CATH) 17 domains

SCOP 2.08 (9 domains)

CATH v4.4 (8 domains)

7. Citations (1)

Source organism organism	Homo sapiens
Common name common_name	Human
NCBI taxonomy ID ncbi_taxonomy_id	9606
Host organism host_organism	Escherichia coli BL21(DE3)

Description description	water
Molecular weight formula_weight	18.0 kDa
Source method src_method	nat
Copy count entity_count	401

The neck-linker of Mus musculus KIF3A fused to the alpha 7 helix of Drosophila melanogaster Kinesin-1 fused to EB1

1. Protein Identity and Related Structures Protein Identity & Related Structures

Chimera protein of mouse KIF3A,fruit fly Kinesin-1 and human EB1

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

Chimera protein of mouse KIF3A,fruit fly Kinesin-1 and human EB1

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

Chimera protein of mouse KIF3A,fruit fly Kinesin-1 and human EB1

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

5jvr__assembly_1__model_1

5jvr__assembly_1__model_1 | I(q)

5jvr__assembly_1__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

Refinement Refinement

Diffraction experiment Diffraction

5. Entities and Polymers Entities & Polymers (2)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

Entity 2 Entity 2 water

6. Fold Classification (SCOP + CATH) 17 domains

SCOP 2.08 (9 domains)

CATH v4.4 (8 domains)

7. Citations (1)