6mzc

Human TFIID BC core

Method: ELECTRON MICROSCOPY
▼

1. Protein Identity and Related Structures Protein Identity & Related Structures

Transcription initiation factor TFIID subunit 2

OrganismNot specified

UniProt Q6P1X5

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 10 Transcription initiation factor TFIID subunit 4 × 1 (O00268) Transcription initiation factor TFIID subunit 5 × 1 (Q15542) Transcription initiation factor TFIID subunit 6 × 1 (P49848) Transcription initiation factor TFIID subunit 6 × 1 (P49848) Transcription initiation factor TFIID subunit 8 × 1 (Q7Z7C8) Transcription initiation factor TFIID subunit 9 × 1 (Q16594) Transcription initiation factor TFIID subunit 10 × 1 (Q12962) Transcription initiation factor TFIID subunit 12 × 1 (Q16514) poly(UNK) × 1 Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name TAF2_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain B; PDBConstruct 1–1199; UniProt 1–1199

Transcription initiation factor TFIID subunit 4

OrganismNot specified

UniProt O00268

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 10 Transcription initiation factor TFIID subunit 2 × 1 (Q6P1X5) Transcription initiation factor TFIID subunit 5 × 1 (Q15542) Transcription initiation factor TFIID subunit 6 × 1 (P49848) Transcription initiation factor TFIID subunit 6 × 1 (P49848) Transcription initiation factor TFIID subunit 8 × 1 (Q7Z7C8) Transcription initiation factor TFIID subunit 9 × 1 (Q16594) Transcription initiation factor TFIID subunit 10 × 1 (Q12962) Transcription initiation factor TFIID subunit 12 × 1 (Q16514) poly(UNK) × 1 Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name TAF4_HUMAN
Isoform —
PDB entities 2
Chains and sequence ranges Author chain E; PDBConstruct 1–1085; UniProt 1–1085

Transcription initiation factor TFIID subunit 5

OrganismNot specified

UniProt Q15542

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 10 Transcription initiation factor TFIID subunit 2 × 1 (Q6P1X5) Transcription initiation factor TFIID subunit 4 × 1 (O00268) Transcription initiation factor TFIID subunit 6 × 1 (P49848) Transcription initiation factor TFIID subunit 6 × 1 (P49848) Transcription initiation factor TFIID subunit 8 × 1 (Q7Z7C8) Transcription initiation factor TFIID subunit 9 × 1 (Q16594) Transcription initiation factor TFIID subunit 10 × 1 (Q12962) Transcription initiation factor TFIID subunit 12 × 1 (Q16514) poly(UNK) × 1 Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name TAF5_HUMAN
Isoform —
PDB entities 3
Chains and sequence ranges Author chain G; PDBConstruct 1–800; UniProt 1–800

Transcription initiation factor TFIID subunit 6

OrganismNot specified

UniProt P49848

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 10 Transcription initiation factor TFIID subunit 2 × 1 (Q6P1X5) Transcription initiation factor TFIID subunit 4 × 1 (O00268) Transcription initiation factor TFIID subunit 5 × 1 (Q15542) Transcription initiation factor TFIID subunit 8 × 1 (Q7Z7C8) Transcription initiation factor TFIID subunit 9 × 1 (Q16594) Transcription initiation factor TFIID subunit 10 × 1 (Q12962) Transcription initiation factor TFIID subunit 12 × 1 (Q16514) poly(UNK) × 1 Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name TAF6_HUMAN
Isoform —
PDB entities 4, 5
Chains and sequence ranges Author chain H; PDBConstruct 1–677; UniProt 1–677 Author chain I; PDBConstruct 1–677; UniProt 38–714

Transcription initiation factor TFIID subunit 8

OrganismNot specified

UniProt Q7Z7C8

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 10 Transcription initiation factor TFIID subunit 2 × 1 (Q6P1X5) Transcription initiation factor TFIID subunit 4 × 1 (O00268) Transcription initiation factor TFIID subunit 5 × 1 (Q15542) Transcription initiation factor TFIID subunit 6 × 1 (P49848) Transcription initiation factor TFIID subunit 6 × 1 (P49848) Transcription initiation factor TFIID subunit 9 × 1 (Q16594) Transcription initiation factor TFIID subunit 10 × 1 (Q12962) Transcription initiation factor TFIID subunit 12 × 1 (Q16514) poly(UNK) × 1 Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name TAF8_HUMAN
Isoform Q7Z7C8-4
PDB entities 6
Chains and sequence ranges Author chain K; PDBConstruct 1–120; UniProt 1–120 Author chain K; PDBConstruct 172–310; UniProt 172–310

Transcription initiation factor TFIID subunit 9

OrganismNot specified

UniProt Q16594

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 10 Transcription initiation factor TFIID subunit 2 × 1 (Q6P1X5) Transcription initiation factor TFIID subunit 4 × 1 (O00268) Transcription initiation factor TFIID subunit 5 × 1 (Q15542) Transcription initiation factor TFIID subunit 6 × 1 (P49848) Transcription initiation factor TFIID subunit 6 × 1 (P49848) Transcription initiation factor TFIID subunit 8 × 1 (Q7Z7C8) Transcription initiation factor TFIID subunit 10 × 1 (Q12962) Transcription initiation factor TFIID subunit 12 × 1 (Q16514) poly(UNK) × 1 Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name TAF9_HUMAN
Isoform —
PDB entities 7
Chains and sequence ranges Author chain M; PDBConstruct 1–109; UniProt 1–109 Author chain M; PDBConstruct 117–264; UniProt 117–264

Transcription initiation factor TFIID subunit 10

OrganismNot specified

UniProt Q12962

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 10 Transcription initiation factor TFIID subunit 2 × 1 (Q6P1X5) Transcription initiation factor TFIID subunit 4 × 1 (O00268) Transcription initiation factor TFIID subunit 5 × 1 (Q15542) Transcription initiation factor TFIID subunit 6 × 1 (P49848) Transcription initiation factor TFIID subunit 6 × 1 (P49848) Transcription initiation factor TFIID subunit 8 × 1 (Q7Z7C8) Transcription initiation factor TFIID subunit 9 × 1 (Q16594) Transcription initiation factor TFIID subunit 12 × 1 (Q16514) poly(UNK) × 1 Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name TAF10_HUMAN
Isoform —
PDB entities 8
Chains and sequence ranges Author chain O; PDBConstruct 1–218; UniProt 1–218

Transcription initiation factor TFIID subunit 12

OrganismNot specified

UniProt Q16514

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 10 Transcription initiation factor TFIID subunit 2 × 1 (Q6P1X5) Transcription initiation factor TFIID subunit 4 × 1 (O00268) Transcription initiation factor TFIID subunit 5 × 1 (Q15542) Transcription initiation factor TFIID subunit 6 × 1 (P49848) Transcription initiation factor TFIID subunit 6 × 1 (P49848) Transcription initiation factor TFIID subunit 8 × 1 (Q7Z7C8) Transcription initiation factor TFIID subunit 9 × 1 (Q16594) Transcription initiation factor TFIID subunit 10 × 1 (Q12962) poly(UNK) × 1 Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name TAF12_HUMAN
Isoform —
PDB entities 9
Chains and sequence ranges Author chain R; PDBConstruct 1–161; UniProt 1–161

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

▼

2. Structure Basics 2. Structure Basics

Entry ID entry_id6mzc
Deposition date deposition_date2018-11-05
Structure title titleHuman TFIID BC core
Keywords keywordsTranscription, DNA, Nuclear; TRANSCRIPTION
Experimental Method methodELECTRON MICROSCOPY
▼

3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

6mzc__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

6mzc__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 109 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

6mzc__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg(Guinier)64.48 Å
Rg (electron density)65.58 Å
Total Rg65.51 Å
Atom count21254
Residues2839
Excluded volume375890 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 6mzc__assembly_1__model_1 decameric (10) Success 4.1.3-1-20251215 (887e7ef) View Download
▶

4. Crystallography and Experiment 4. Crystallography & Experiment

▶

5. Entities and Polymers Entities & Polymers (10)

▶

7. Citations (1)