9y1o

The structure of the Plasmodium falciparum 20S proteasome

Method: ELECTRON MICROSCOPY

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1. Protein Identity and Related Structures Protein Identity & Related Structures

Proteasome subunit alpha type-6

Plasmodium falciparum Dd2

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 28	Proteasome subunit alpha type-2 × 2 （C6KST3） Proteasome subunit alpha type-3 × 2 （Q8IDG3） Proteasome subunit alpha type-4 × 2 （Q8IDG2） Proteasome subunit alpha type-5 × 2 （A0A0L7LVZ5） Proteasome subunit alpha type-1 × 2 （Q8IK90） Proteasome subunit alpha type-3 × 2 （O77396） Proteasome endopeptidase complex × 2 （A0A0L7M1M6） Proteasome subunit beta-2 × 2 （Q8I6T3） Proteasome subunit beta-3 × 2 （Q8I261） Proteasome subunit beta-4 × 2 （Q8IKC9） Proteasome subunit beta-5 × 2 （Q8IJT1） Proteasome subunit beta × 2 （A0A0L7LW03） Proteasome subunit beta × 2 （A0A2I0BU46）	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	Q8IAR3_PLAF7
Isoform	—
PDB entities	1
Chains and sequence ranges	Author chain A； PDBConstruct 1–260； UniProt 1–260 Author chain O； PDBConstruct 1–260； UniProt 1–260

Proteasome subunit alpha type-2

Plasmodium falciparum Dd2

UniProt C6KST3

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 28	Proteasome subunit alpha type-6 × 2 （Q8IAR3） Proteasome subunit alpha type-3 × 2 （Q8IDG3） Proteasome subunit alpha type-4 × 2 （Q8IDG2） Proteasome subunit alpha type-5 × 2 （A0A0L7LVZ5） Proteasome subunit alpha type-1 × 2 （Q8IK90） Proteasome subunit alpha type-3 × 2 （O77396） Proteasome endopeptidase complex × 2 （A0A0L7M1M6） Proteasome subunit beta-2 × 2 （Q8I6T3） Proteasome subunit beta-3 × 2 （Q8I261） Proteasome subunit beta-4 × 2 （Q8IKC9） Proteasome subunit beta-5 × 2 （Q8IJT1） Proteasome subunit beta × 2 （A0A0L7LW03） Proteasome subunit beta × 2 （A0A2I0BU46）	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	C6KST3_PLAF7
Isoform	—
PDB entities	2
Chains and sequence ranges	Author chain B； PDBConstruct 1–235； UniProt 1–235 Author chain P； PDBConstruct 1–235； UniProt 1–235

Proteasome subunit alpha type-3

Plasmodium falciparum Dd2

UniProt Q8IDG3

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 28	Proteasome subunit alpha type-6 × 2 （Q8IAR3） Proteasome subunit alpha type-2 × 2 （C6KST3） Proteasome subunit alpha type-4 × 2 （Q8IDG2） Proteasome subunit alpha type-5 × 2 （A0A0L7LVZ5） Proteasome subunit alpha type-1 × 2 （Q8IK90） Proteasome subunit alpha type-3 × 2 （O77396） Proteasome endopeptidase complex × 2 （A0A0L7M1M6） Proteasome subunit beta-2 × 2 （Q8I6T3） Proteasome subunit beta-3 × 2 （Q8I261） Proteasome subunit beta-4 × 2 （Q8IKC9） Proteasome subunit beta-5 × 2 （Q8IJT1） Proteasome subunit beta × 2 （A0A0L7LW03） Proteasome subunit beta × 2 （A0A2I0BU46）	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	Q8IDG3_PLAF7
Isoform	—
PDB entities	3
Chains and sequence ranges	Author chain C； PDBConstruct 1–246； UniProt 1–246 Author chain Q； PDBConstruct 1–246； UniProt 1–246

Proteasome subunit alpha type-4

Plasmodium falciparum Dd2

UniProt Q8IDG2

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 28	Proteasome subunit alpha type-6 × 2 （Q8IAR3） Proteasome subunit alpha type-2 × 2 （C6KST3） Proteasome subunit alpha type-3 × 2 （Q8IDG3） Proteasome subunit alpha type-5 × 2 （A0A0L7LVZ5） Proteasome subunit alpha type-1 × 2 （Q8IK90） Proteasome subunit alpha type-3 × 2 （O77396） Proteasome endopeptidase complex × 2 （A0A0L7M1M6） Proteasome subunit beta-2 × 2 （Q8I6T3） Proteasome subunit beta-3 × 2 （Q8I261） Proteasome subunit beta-4 × 2 （Q8IKC9） Proteasome subunit beta-5 × 2 （Q8IJT1） Proteasome subunit beta × 2 （A0A0L7LW03） Proteasome subunit beta × 2 （A0A2I0BU46）	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	Q8IDG2_PLAF7
Isoform	—
PDB entities	4
Chains and sequence ranges	Author chain D； PDBConstruct 1–241； UniProt 1–241 Author chain R； PDBConstruct 1–241； UniProt 1–241

Proteasome subunit alpha type-5

Plasmodium falciparum Dd2

UniProt A0A0L7LVZ5

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 28	Proteasome subunit alpha type-6 × 2 （Q8IAR3） Proteasome subunit alpha type-2 × 2 （C6KST3） Proteasome subunit alpha type-3 × 2 （Q8IDG3） Proteasome subunit alpha type-4 × 2 （Q8IDG2） Proteasome subunit alpha type-1 × 2 （Q8IK90） Proteasome subunit alpha type-3 × 2 （O77396） Proteasome endopeptidase complex × 2 （A0A0L7M1M6） Proteasome subunit beta-2 × 2 （Q8I6T3） Proteasome subunit beta-3 × 2 （Q8I261） Proteasome subunit beta-4 × 2 （Q8IKC9） Proteasome subunit beta-5 × 2 （Q8IJT1） Proteasome subunit beta × 2 （A0A0L7LW03） Proteasome subunit beta × 2 （A0A2I0BU46）	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	A0A0L7LVZ5_PLAF4
Isoform	—
PDB entities	5
Chains and sequence ranges	Author chain E； PDBConstruct 1–256； UniProt 1–256 Author chain S； PDBConstruct 1–256； UniProt 1–256

Proteasome subunit alpha type-1

Plasmodium falciparum Dd2

UniProt Q8IK90

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 28	Proteasome subunit alpha type-6 × 2 （Q8IAR3） Proteasome subunit alpha type-2 × 2 （C6KST3） Proteasome subunit alpha type-3 × 2 （Q8IDG3） Proteasome subunit alpha type-4 × 2 （Q8IDG2） Proteasome subunit alpha type-5 × 2 （A0A0L7LVZ5） Proteasome subunit alpha type-3 × 2 （O77396） Proteasome endopeptidase complex × 2 （A0A0L7M1M6） Proteasome subunit beta-2 × 2 （Q8I6T3） Proteasome subunit beta-3 × 2 （Q8I261） Proteasome subunit beta-4 × 2 （Q8IKC9） Proteasome subunit beta-5 × 2 （Q8IJT1） Proteasome subunit beta × 2 （A0A0L7LW03） Proteasome subunit beta × 2 （A0A2I0BU46）	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	Q8IK90_PLAF7
Isoform	—
PDB entities	6
Chains and sequence ranges	Author chain F； PDBConstruct 1–254； UniProt 1–254 Author chain T； PDBConstruct 1–254； UniProt 1–254

Proteasome subunit alpha type-3

Plasmodium falciparum Dd2

UniProt O77396

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 28	Proteasome subunit alpha type-6 × 2 （Q8IAR3） Proteasome subunit alpha type-2 × 2 （C6KST3） Proteasome subunit alpha type-3 × 2 （Q8IDG3） Proteasome subunit alpha type-4 × 2 （Q8IDG2） Proteasome subunit alpha type-5 × 2 （A0A0L7LVZ5） Proteasome subunit alpha type-1 × 2 （Q8IK90） Proteasome endopeptidase complex × 2 （A0A0L7M1M6） Proteasome subunit beta-2 × 2 （Q8I6T3） Proteasome subunit beta-3 × 2 （Q8I261） Proteasome subunit beta-4 × 2 （Q8IKC9） Proteasome subunit beta-5 × 2 （Q8IJT1） Proteasome subunit beta × 2 （A0A0L7LW03） Proteasome subunit beta × 2 （A0A2I0BU46）	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	O77396_PLAF7
Isoform	—
PDB entities	7
Chains and sequence ranges	Author chain G； PDBConstruct 1–252； UniProt 1–252 Author chain U； PDBConstruct 1–252； UniProt 1–252

Proteasome endopeptidase complex

Plasmodium falciparum Dd2

UniProt A0A0L7M1M6

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 28	Proteasome subunit alpha type-6 × 2 （Q8IAR3） Proteasome subunit alpha type-2 × 2 （C6KST3） Proteasome subunit alpha type-3 × 2 （Q8IDG3） Proteasome subunit alpha type-4 × 2 （Q8IDG2） Proteasome subunit alpha type-5 × 2 （A0A0L7LVZ5） Proteasome subunit alpha type-1 × 2 （Q8IK90） Proteasome subunit alpha type-3 × 2 （O77396） Proteasome subunit beta-2 × 2 （Q8I6T3） Proteasome subunit beta-3 × 2 （Q8I261） Proteasome subunit beta-4 × 2 （Q8IKC9） Proteasome subunit beta-5 × 2 （Q8IJT1） Proteasome subunit beta × 2 （A0A0L7LW03） Proteasome subunit beta × 2 （A0A2I0BU46）	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	A0A0L7M1M6_PLAF4
Isoform	—
PDB entities	8
Chains and sequence ranges	Author chain H； PDBConstruct 1–252； UniProt 31–282 Author chain V； PDBConstruct 1–252； UniProt 31–282

Proteasome subunit beta-2

Plasmodium falciparum Dd2

UniProt Q8I6T3

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 28	Proteasome subunit alpha type-6 × 2 （Q8IAR3） Proteasome subunit alpha type-2 × 2 （C6KST3） Proteasome subunit alpha type-3 × 2 （Q8IDG3） Proteasome subunit alpha type-4 × 2 （Q8IDG2） Proteasome subunit alpha type-5 × 2 （A0A0L7LVZ5） Proteasome subunit alpha type-1 × 2 （Q8IK90） Proteasome subunit alpha type-3 × 2 （O77396） Proteasome endopeptidase complex × 2 （A0A0L7M1M6） Proteasome subunit beta-3 × 2 （Q8I261） Proteasome subunit beta-4 × 2 （Q8IKC9） Proteasome subunit beta-5 × 2 （Q8IJT1） Proteasome subunit beta × 2 （A0A0L7LW03） Proteasome subunit beta × 2 （A0A2I0BU46）	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	Q8I6T3_PLAF7
Isoform	—
PDB entities	9
Chains and sequence ranges	Author chain I； PDBConstruct 1–229； UniProt 42–270 Author chain W； PDBConstruct 1–229； UniProt 42–270

Proteasome subunit beta-3

Plasmodium falciparum Dd2

UniProt Q8I261

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 28	Proteasome subunit alpha type-6 × 2 （Q8IAR3） Proteasome subunit alpha type-2 × 2 （C6KST3） Proteasome subunit alpha type-3 × 2 （Q8IDG3） Proteasome subunit alpha type-4 × 2 （Q8IDG2） Proteasome subunit alpha type-5 × 2 （A0A0L7LVZ5） Proteasome subunit alpha type-1 × 2 （Q8IK90） Proteasome subunit alpha type-3 × 2 （O77396） Proteasome endopeptidase complex × 2 （A0A0L7M1M6） Proteasome subunit beta-2 × 2 （Q8I6T3） Proteasome subunit beta-4 × 2 （Q8IKC9） Proteasome subunit beta-5 × 2 （Q8IJT1） Proteasome subunit beta × 2 （A0A0L7LW03） Proteasome subunit beta × 2 （A0A2I0BU46）	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	Q8I261_PLAF7
Isoform	—
PDB entities	10
Chains and sequence ranges	Author chain J； PDBConstruct 1–218； UniProt 1–218 Author chain X； PDBConstruct 1–218； UniProt 1–218

Proteasome subunit beta-4

Plasmodium falciparum Dd2

UniProt Q8IKC9

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 28	Proteasome subunit alpha type-6 × 2 （Q8IAR3） Proteasome subunit alpha type-2 × 2 （C6KST3） Proteasome subunit alpha type-3 × 2 （Q8IDG3） Proteasome subunit alpha type-4 × 2 （Q8IDG2） Proteasome subunit alpha type-5 × 2 （A0A0L7LVZ5） Proteasome subunit alpha type-1 × 2 （Q8IK90） Proteasome subunit alpha type-3 × 2 （O77396） Proteasome endopeptidase complex × 2 （A0A0L7M1M6） Proteasome subunit beta-2 × 2 （Q8I6T3） Proteasome subunit beta-3 × 2 （Q8I261） Proteasome subunit beta-5 × 2 （Q8IJT1） Proteasome subunit beta × 2 （A0A0L7LW03） Proteasome subunit beta × 2 （A0A2I0BU46）	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	Q8IKC9_PLAF7
Isoform	—
PDB entities	11
Chains and sequence ranges	Author chain K； PDBConstruct 1–195； UniProt 1–195 Author chain Y； PDBConstruct 1–195； UniProt 1–195

Proteasome subunit beta-5

Plasmodium falciparum Dd2

UniProt Q8IJT1

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 28	Proteasome subunit alpha type-6 × 2 （Q8IAR3） Proteasome subunit alpha type-2 × 2 （C6KST3） Proteasome subunit alpha type-3 × 2 （Q8IDG3） Proteasome subunit alpha type-4 × 2 （Q8IDG2） Proteasome subunit alpha type-5 × 2 （A0A0L7LVZ5） Proteasome subunit alpha type-1 × 2 （Q8IK90） Proteasome subunit alpha type-3 × 2 （O77396） Proteasome endopeptidase complex × 2 （A0A0L7M1M6） Proteasome subunit beta-2 × 2 （Q8I6T3） Proteasome subunit beta-3 × 2 （Q8I261） Proteasome subunit beta-4 × 2 （Q8IKC9） Proteasome subunit beta × 2 （A0A0L7LW03） Proteasome subunit beta × 2 （A0A2I0BU46）	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	Q8IJT1_PLAF7
Isoform	—
PDB entities	12
Chains and sequence ranges	Author chain L； PDBConstruct 1–211； UniProt 61–271 Author chain Z； PDBConstruct 1–211； UniProt 61–271

Proteasome subunit beta

Plasmodium falciparum Dd2

UniProt A0A0L7LW03

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 28	Proteasome subunit alpha type-6 × 2 （Q8IAR3） Proteasome subunit alpha type-2 × 2 （C6KST3） Proteasome subunit alpha type-3 × 2 （Q8IDG3） Proteasome subunit alpha type-4 × 2 （Q8IDG2） Proteasome subunit alpha type-5 × 2 （A0A0L7LVZ5） Proteasome subunit alpha type-1 × 2 （Q8IK90） Proteasome subunit alpha type-3 × 2 （O77396） Proteasome endopeptidase complex × 2 （A0A0L7M1M6） Proteasome subunit beta-2 × 2 （Q8I6T3） Proteasome subunit beta-3 × 2 （Q8I261） Proteasome subunit beta-4 × 2 （Q8IKC9） Proteasome subunit beta-5 × 2 （Q8IJT1） Proteasome subunit beta × 2 （A0A2I0BU46）	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	A0A0L7LW03_PLAF4
Isoform	—
PDB entities	13
Chains and sequence ranges	Author chain N； PDBConstruct 1–265； UniProt 1–265 Author chain b； PDBConstruct 1–265； UniProt 1–265

Proteasome subunit beta

Plasmodium falciparum Dd2

UniProt A0A2I0BU46

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 28	Proteasome subunit alpha type-6 × 2 （Q8IAR3） Proteasome subunit alpha type-2 × 2 （C6KST3） Proteasome subunit alpha type-3 × 2 （Q8IDG3） Proteasome subunit alpha type-4 × 2 （Q8IDG2） Proteasome subunit alpha type-5 × 2 （A0A0L7LVZ5） Proteasome subunit alpha type-1 × 2 （Q8IK90） Proteasome subunit alpha type-3 × 2 （O77396） Proteasome endopeptidase complex × 2 （A0A0L7M1M6） Proteasome subunit beta-2 × 2 （Q8I6T3） Proteasome subunit beta-3 × 2 （Q8I261） Proteasome subunit beta-4 × 2 （Q8IKC9） Proteasome subunit beta-5 × 2 （Q8IJT1） Proteasome subunit beta × 2 （A0A0L7LW03）	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	A0A2I0BU46_PLAFO
Isoform	—
PDB entities	14
Chains and sequence ranges	Author chain M； PDBConstruct 1–240； UniProt 1–240 Author chain a； PDBConstruct 1–240； UniProt 1–240

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id	9y1o
Deposition date deposition_date	2025-08-29
Structure title title	The structure of the Plasmodium falciparum 20S proteasome
Keywords keywords	Proteasome, 20S proteasome, Plasmodium falciparum, HYDROLASE; HYDROLASE
Experimental Method method	ELECTRON MICROSCOPY

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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

9y1o__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

9y1o__assembly_1__model_1 | I(q)

100 plotted points; both axes use logarithmic scales.

9y1o__assembly_1__model_1 | P(r) · Pending

P(r) will be calculated and displayed separately for the same assembly/model.

Rg（Guinier）	60.53 Å
Rg (electron density)	60.10 Å
Total Rg	60.30 Å
Atom count	94870
Residues	6250
Excluded volume	860270 Å³
Maximum q	0.500 Å⁻¹

Assembly	Model	Structure unit	Oligomeric description	Status	CRYSOL	Actions
1	1	`9y1o__assembly_1__model_1`	28-meric （28）	Success	4.1.3-1-20251215 (887e7ef)	View Download

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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (14)

Entity 1 Entity 1 polymer

Description description	Proteasome subunit alpha type-6
Molecular weight formula_weight	29531.7 kDa
EC 编号 ec_number	3.4.25.1
Source method src_method	man
Copy count entity_count	2

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	A,O
Atom count atom_count	94870

MVRPSQSMYDRHLTIFSPDGNLYQIEYAIKAVKNTNITSVGVKGENCAVIISQKKMATQYISQDKLLDYNNITNIYNITDEIGCSMVGMPGDCLSMVYKARSEASEFLYSNGYNVNAETLCRNICDKIQVYTQHAYMRLHACSGMIIGIDENNKPELFKFDPSGFCAGYRACVIGNKEQESISVLERLLEKRKKKIQQETIDEDIRNTTILAIEALQTILAFDLKASEIEVAIVSTKNRNFTQISEKEIDNYLTYIAERD

Source Source

Source organism organism	Plasmodium falciparum Dd2
NCBI taxonomy ID ncbi_taxonomy_id	57267
Host organism host_organism	Spodoptera frugiperda

Entity 2 Entity 2 polymer

Description description	Proteasome subunit alpha type-2
Molecular weight formula_weight	26556.4 kDa
Source method src_method	man
Copy count entity_count	2

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	B,P

MADGEYSFSLTTFSPTGKLVQIEYALNRVSSSSPALGIRAKNGVIIATEKKSPNELIEENSIFKIQQISEHIGIVYAGMPGDFRVLLKRARKEAIRYSLQYGSEILVKELVKIIASIVQEFTQTGGVRPFGLSLLICGVDVYGYHLYQIDPSGCYFNWMATCVGKDYQNNMSFLEKRYNKDIEIEDAIHTAILTLKESYEGVLNEKNIEIGVAYDNKPFKILTQNEIKDYLIEIE

Source Source

Source organism organism	Plasmodium falciparum Dd2
NCBI taxonomy ID ncbi_taxonomy_id	57267
Host organism host_organism	Spodoptera frugiperda

Entity 3 Entity 3 polymer

Description description	Proteasome subunit alpha type-3
Molecular weight formula_weight	27977.7 kDa
Source method src_method	man
Copy count entity_count	2

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	C,Q

MARRYDSRTTTFSPEGRLYQVEYALEAINNASITIGLITKDGVILGADKVFISKLIDKANNYEKIYKIDKHIFCGVAGLNADANILINQSRLYAQRYLYNYNEVQPVSQLVVQICDIKQSYTQYGGLRPYGVSFLIGGYDTKDGYQLYHTDPSGNYSGWFATAIGTNNLTASSVLKQEWKNDMTLEEGLLLALKTLAKSTDTEIPKSEKIELAYLTNKDGEVYQKYLTEKEIEELIKLYTQKYIKE

Source Source

Source organism organism	Plasmodium falciparum Dd2
NCBI taxonomy ID ncbi_taxonomy_id	57267
Host organism host_organism	Spodoptera frugiperda

Entity 4 Entity 4 polymer

Description description	Proteasome subunit alpha type-4
Molecular weight formula_weight	27263.3 kDa
Source method src_method	man
Copy count entity_count	2

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	D,R

MSYDRAITVFSPDGHLLQVEHALEAVKKGGCAVAIKSSNFAVLAVEKKNIPKLQNPKTTEKLIKLDEHNCLAFAGLNADARVLVNKTRLECQRYYLNMDEPAPVDYIAKYVAKVQQKFTHRGGVRPFGIATLIAGFKNNKEICIYQTEPSGIYAAWKAQAIGKNAKIVQEFLEKNYQENMEQKDCIFLALKAIFEVVELSSKNVEVALLTEKDLTFIEEQEINSMVELIDQERTKNNEQNE

Source Source

Source organism organism	Plasmodium falciparum Dd2
NCBI taxonomy ID ncbi_taxonomy_id	57267
Host organism host_organism	Spodoptera frugiperda

Entity 5 Entity 5 polymer

Description description	Proteasome subunit alpha type-5
Molecular weight formula_weight	28417.4 kDa
Source method src_method	man
Copy count entity_count	2

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	E,S

MFSTRSEYDRGVNTFSPEGRLFQVEYALGAIKLGSTAVGICVNDGVILASERRISSTLIEKDSVEKLLSIDDHIGCAMSGLMADARTLIDYARVECNHYKFIYNENINIKSCVELISELALDFSNLSDSKRKKIMSRPFGVALLIGGVDKNGPCLWYTEPSGTNTRFSAASIGSAQEGAELLLQENYKKDMTFEQAEILALTVLRQVMEDKLSTSNVEICAIKKSDQTFYKYNTDDISRIIDVLPSPVYPTIDMTA

Source Source

Source organism organism	Plasmodium falciparum Dd2
NCBI taxonomy ID ncbi_taxonomy_id	57267
Host organism host_organism	Spodoptera frugiperda

Entity 6 Entity 6 polymer

Description description	Proteasome subunit alpha type-1
Molecular weight formula_weight	28871.7 kDa
Source method src_method	man
Copy count entity_count	2

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	F,T

MYRNLYDTDNIIYSPEGRLYQVEYASEAIKQGTCAVAIKSKDYVVVSGLKKCISKLSFPQEKIFKIDDYIGISMSGITSDAKVLTKFMQNECLSHKFLYNENINIESLVRSVADKYQKNTQKSSKRAFGVGLMIAAYHNEPCIFETRPNGSYFEYDALSFGARSHASKTYLEKNLHLFEECSLEELILHCLKALKCSLSSESELTISNTALAVVGKNHPWQEISSLQLEEYLSKVKMDAEQEQVEENVQNEANE

Source Source

Source organism organism	Plasmodium falciparum Dd2
NCBI taxonomy ID ncbi_taxonomy_id	57267
Host organism host_organism	Spodoptera frugiperda

Entity 7 Entity 7 polymer

Description description	Proteasome subunit alpha type-3
Molecular weight formula_weight	29324.3 kDa
EC 编号 ec_number	3.4.25.1
Source method src_method	man
Copy count entity_count	2

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	G,U

MAGLSAGYDLSVSTFSPDGRLYQVEYIYKSINNNNTALCLECKDGIICCCINSNMDKNKMIKKNSYNRIYHVNNNIIITYSGFDGDARNIIDRARSEANTYYYNFHTNIPLHILVNRISLYIHAYTLYWHMRPFAASIIISSFNEKDKGDIYCIEPNGACYKYSGIVIGKNKEMFKTEIEKKDYKDINVRDAIEDIYKFILTSDDHMNKNNLQNLVNFSWICKESSYEFQNIHEEILTPALNKAVEYIEKLN

Source Source

Source organism organism	Plasmodium falciparum Dd2
NCBI taxonomy ID ncbi_taxonomy_id	57267
Host organism host_organism	Spodoptera frugiperda

Entity 8 Entity 8 polymer

Description description	Proteasome endopeptidase complex
Molecular weight formula_weight	29143.9 kDa
Source method src_method	man
Copy count entity_count	2

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	H,V

TTIIGIIYDNGVMLACDSRTSSGTFISNKCSRKINRINENLYVCRSGASAHSQKIIEIIKHYCVSMKNENRKKGRFHEGETIYDETTYDEEIDIDSINYLDYNNNNDNNLVTKNKYFYEDKFNDYNPLVENVAHITKKIIYTNNNFLSCALIFGGYDKIKKQQLYAVNLNGSIIEKHDFAVSGSGSIYIQSYLQDKYKKFMTKKECFNLILNCVKYAMHNDNSSGGLIRIVNITKSFVEEFTVVNTQMNFQY

Source Source

Source organism organism	Plasmodium falciparum Dd2
NCBI taxonomy ID ncbi_taxonomy_id	57267
Host organism host_organism	Spodoptera frugiperda

Entity 9 Entity 9 polymer

Description description	Proteasome subunit beta-2
Molecular weight formula_weight	25104.9 kDa
Source method src_method	man
Copy count entity_count	2

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	I,W

TTICGLVCQNAVILGADTRATEGPIVADKNCSKLHYISKNIWCAGAGVAGDLEHTTLWLQHNVELHRLNTNTQPRVSMCVSRLTQELFKYQGYKVCAIVLGGVDVNGPQLYGIHPHGSSCLLPFTALGSGSLNAMAVLEAKYRDNMTIEEGKNLVCEAICAGIFNDLGSGGNVDICVITKDSYQHIRPYKEPNMRLYHLPHPTIYPKGTTPILSEKIEYIKKFISVEDA

Source Source

Source organism organism	Plasmodium falciparum Dd2
NCBI taxonomy ID ncbi_taxonomy_id	57267
Host organism host_organism	Spodoptera frugiperda

Entity 10 Entity 10 polymer

Description description	Proteasome subunit beta-3
Molecular weight formula_weight	24533.1 kDa
Source method src_method	man
Copy count entity_count	2

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	J,X

MGSIYNYNGGCVLGMSGSNCVAIACDLRLGANTFTTVSTKFSKIFKMNNNVYVGLSGLATDIQTLYEILRYRVNLYEVRQDAEMDVECFANMLSSILYSNRFSPYFVNPIVVGFKLKHYVDEEGEKKVNYEPYLTAYDLIGAKCETRDFVVNGVTSEQLFGMCESLYVKDQDENGLFETISQCLLSALDRDCISGWGAEVLVLTPEKIIKKKLKARMD

Source Source

Source organism organism	Plasmodium falciparum Dd2
NCBI taxonomy ID ncbi_taxonomy_id	57267
Host organism host_organism	Spodoptera frugiperda

Entity 11 Entity 11 polymer

Description description	Proteasome subunit beta-4
Molecular weight formula_weight	22889.1 kDa
Source method src_method	man
Copy count entity_count	2

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	K,Y

MDTLIGLRGNNFVVLAADTYSINSIIKLKNDDNTKFYDIHGNKCLLLGGSIGDRLQFGEFIRKNVHLYQYQNNTDMFVKSFAFFTRKNLAYYLRRNPFEVNCLIAGYDKKDGYQLYWCDYLSNMDSVNKGAHGYGAYLVSAILDKYYHENLTVDEALDIFKLCFEELKKRFLLTQINYELRIMYDNKVETQYVTV

Source Source

Source organism organism	Plasmodium falciparum Dd2
NCBI taxonomy ID ncbi_taxonomy_id	57267
Host organism host_organism	Spodoptera frugiperda

Entity 12 Entity 12 polymer

Description description	Proteasome subunit beta-5
Molecular weight formula_weight	23620.6 kDa
Source method src_method	man
Copy count entity_count	2

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	L,Z

TTTLAFKFKDGIIVAVDSRASMGSFISSQNVEKIIEINKNILGTMAGGAADCLYWEKYLGKIIKIYELRNNEKISVRAASTILSNILYQYKGYGLCCGIILSGYDHTGFNMFYVDDSGKKVEGNLFSCGSGSTYAYSILDSAYDYNLNLDQAVELARNAIYHATFRDGGSGGKVRVFHIHKNGYDKIIEGEDVFDLHYHYTNPEQKDQYVM

Source Source

Source organism organism	Plasmodium falciparum Dd2
NCBI taxonomy ID ncbi_taxonomy_id	57267
Host organism host_organism	Spodoptera frugiperda

Entity 13 Entity 13 polymer

Description description	Proteasome subunit beta
Molecular weight formula_weight	34823.0 kDa
Source method src_method	man
Copy count entity_count	2

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	N,b

MTLGPVVTGTSVIAIKYKHGIMIAADRKASYGSYAKFQNVERIFKINNKTVMGFSGELADAQYLHELLTRKNINNLSEKKRKEDMYTPQHYHSYVSRVFYVRKNRIDPLFNNIIIAGINSQKYDNNDDNVLLYTNKNNDDEQNEYKNNEEYKEIHKDDLYIGFVDMHGTNFCDDYITTGYARYFALTLLRDHYKDNMTEEEARILINECLRILYFRDATSSNFIQIVKVTSKGVEYEEPYILPCVLNSADYVYPSTLLPPAGCMWENLYFQSSAWSHPQFEKGGGSGGGSGGSAWSHPQFEK

Source Source

Source organism organism	Plasmodium falciparum Dd2
NCBI taxonomy ID ncbi_taxonomy_id	57267
Host organism host_organism	Spodoptera frugiperda

Entity 14 Entity 14 polymer

Description description	Proteasome subunit beta
Molecular weight formula_weight	27301.2 kDa
Source method src_method	man
Copy count entity_count	2

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	M,a

MDLILYNDNLTEKKTEKENVIEHGRGFKRWYPYIDNGGTVIGLTGKDYVILAADTRLSLSYSIYTRFCPKISKLTDKCIIGSSGMQSDIKTLHSLLQKKIQLFVLEHSHYPDIHVIARLLCVILYSRRFFPYYAFNILAGVDENNKGVLYNYDSVGSYCEATHSCVGSGSQLILPILDNRVEQKNQLIKNTNFNLGDDINFVKDAITSATERDIYTGDKTLIYVIDKMGINVNTLDLKQD

Source Source

Source organism organism	Plasmodium falciparum Dd2
NCBI taxonomy ID ncbi_taxonomy_id	57267
Host organism host_organism	Spodoptera frugiperda

▶

Unit-cell length a length_a	1.000 Å
Unit-cell length b length_b	1.000 Å
Unit-cell length c length_c	1.000 Å
Unit-cell angle α angle_alpha	90.00 °
Unit-cell angle β angle_beta	90.00 °
Unit-cell angle γ angle_gamma	90.00 °
Molecules per unit cell Z z_pdb	—

Space group space_group	P 1
Space-group number int_tables_number	1
Crystal system crystal_system	triclinic

Resolution resolution	3.10 Å
Resolution测定Method resolution_method	—
颗粒数 num_particles	166209

The structure of the Plasmodium falciparum 20S proteasome

1. Protein Identity and Related Structures Protein Identity & Related Structures

Proteasome subunit alpha type-6

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

Proteasome subunit alpha type-2

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

Proteasome subunit alpha type-3

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

Proteasome subunit alpha type-4

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

Proteasome subunit alpha type-5

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

Proteasome subunit alpha type-1

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

Proteasome subunit alpha type-3

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

Proteasome endopeptidase complex

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

Proteasome subunit beta-2

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

Proteasome subunit beta-3

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer