Current Protein Identity:A0A024B7W1 New Search
Main Difference Dimensions in This Set
Different construct Different mutation/modification Different assembly state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
5GZR Zika virus E protein complexed with a neutralizing antibody Z23-Fab Deposited 2016-10-01 Assembly 1 Protein heterocomplex Heteromer;Protein × 600 PDB declaration: 600-meric(600) Consistent with protein count
Chain A 291–794(504 aa)
Chain B 291–794(504 aa)
Chain C 291–794(504 aa)
Chain D 216–290(75 aa)
Chain E 216–290(75 aa)
Chain F 216–290(75 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE;3 uL Zika virus-Z23 Fab complex sample was transferred onto a glow-discharged ultra-thin carbon-coated copper grid (Purchased from Zhongjingkeyi Company, China) followed by 60s waiting and blotted for 2s with filter paper before plugging into liquid ethane using the FEI Vitrobot Mark IV
Resolution 9.40 Å
5GZR Zika virus E protein complexed with a neutralizing antibody Z23-Fab Deposited 2016-10-01 Assembly 2 Protein heterocomplex Heteromer;Protein × 10 PDB declaration: decameric(10) Consistent with protein count
Chain A 291–794(504 aa)
Chain B 291–794(504 aa)
Chain C 291–794(504 aa)
Chain D 216–290(75 aa)
Chain E 216–290(75 aa)
Chain F 216–290(75 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE;3 uL Zika virus-Z23 Fab complex sample was transferred onto a glow-discharged ultra-thin carbon-coated copper grid (Purchased from Zhongjingkeyi Company, China) followed by 60s waiting and blotted for 2s with filter paper before plugging into liquid ethane using the FEI Vitrobot Mark IV
Resolution 9.40 Å
5GZR Zika virus E protein complexed with a neutralizing antibody Z23-Fab Deposited 2016-10-01 Assembly 3 Protein heterocomplex Heteromer;Protein × 50 PDB declaration: 50-meric(50) Consistent with protein count
Chain A 291–794(504 aa)
Chain B 291–794(504 aa)
Chain C 291–794(504 aa)
Chain D 216–290(75 aa)
Chain E 216–290(75 aa)
Chain F 216–290(75 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE;3 uL Zika virus-Z23 Fab complex sample was transferred onto a glow-discharged ultra-thin carbon-coated copper grid (Purchased from Zhongjingkeyi Company, China) followed by 60s waiting and blotted for 2s with filter paper before plugging into liquid ethane using the FEI Vitrobot Mark IV
Resolution 9.40 Å
5GZR Zika virus E protein complexed with a neutralizing antibody Z23-Fab Deposited 2016-10-01 Assembly 4 Protein heterocomplex Heteromer;Protein × 60 PDB declaration: 60-meric(60) Consistent with protein count
Chain A 291–794(504 aa)
Chain B 291–794(504 aa)
Chain C 291–794(504 aa)
Chain D 216–290(75 aa)
Chain E 216–290(75 aa)
Chain F 216–290(75 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE;3 uL Zika virus-Z23 Fab complex sample was transferred onto a glow-discharged ultra-thin carbon-coated copper grid (Purchased from Zhongjingkeyi Company, China) followed by 60s waiting and blotted for 2s with filter paper before plugging into liquid ethane using the FEI Vitrobot Mark IV
Resolution 9.40 Å
5GZR Zika virus E protein complexed with a neutralizing antibody Z23-Fab Deposited 2016-10-01 Assembly 5 Protein heterocomplex Heteromer;Protein × 10 PDB declaration: decameric(10) Consistent with protein count
Chain A 291–794(504 aa)
Chain B 291–794(504 aa)
Chain C 291–794(504 aa)
Chain D 216–290(75 aa)
Chain E 216–290(75 aa)
Chain F 216–290(75 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE;3 uL Zika virus-Z23 Fab complex sample was transferred onto a glow-discharged ultra-thin carbon-coated copper grid (Purchased from Zhongjingkeyi Company, China) followed by 60s waiting and blotted for 2s with filter paper before plugging into liquid ethane using the FEI Vitrobot Mark IV
Resolution 9.40 Å
5GZR Zika virus E protein complexed with a neutralizing antibody Z23-Fab Deposited 2016-10-01 Assembly 6 Protein heterocomplex Heteromer;Protein × 600 PDB declaration: 600-meric(600) Consistent with protein count
Chain A 291–794(504 aa)
Chain B 291–794(504 aa)
Chain C 291–794(504 aa)
Chain D 216–290(75 aa)
Chain E 216–290(75 aa)
Chain F 216–290(75 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE;3 uL Zika virus-Z23 Fab complex sample was transferred onto a glow-discharged ultra-thin carbon-coated copper grid (Purchased from Zhongjingkeyi Company, China) followed by 60s waiting and blotted for 2s with filter paper before plugging into liquid ethane using the FEI Vitrobot Mark IV
Resolution 9.40 Å
5H30 Cryo-EM structure of zika virus complexed with Fab C10 at pH 6.5 Deposited 2016-10-19 Assembly 1 Protein heterocomplex Heteromer;Protein × 720 PDB declaration: 720-meric(720) Consistent with protein count
Chain A 291–794(504 aa)
Chain B 291–794(504 aa)
Chain C 291–794(504 aa)
Chain D 216–290(75 aa)
Chain E 216–290(75 aa)
Chain F 216–290(75 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 6.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.40 Å
5H30 Cryo-EM structure of zika virus complexed with Fab C10 at pH 6.5 Deposited 2016-10-19 Assembly 2 Protein heterocomplex Heteromer;Protein × 12 PDB declaration: dodecameric(12) Consistent with protein count
Chain A 291–794(504 aa)
Chain B 291–794(504 aa)
Chain C 291–794(504 aa)
Chain D 216–290(75 aa)
Chain E 216–290(75 aa)
Chain F 216–290(75 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 6.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.40 Å
5H30 Cryo-EM structure of zika virus complexed with Fab C10 at pH 6.5 Deposited 2016-10-19 Assembly 3 Protein heterocomplex Heteromer;Protein × 60 PDB declaration: 60-meric(60) Consistent with protein count
Chain A 291–794(504 aa)
Chain B 291–794(504 aa)
Chain C 291–794(504 aa)
Chain D 216–290(75 aa)
Chain E 216–290(75 aa)
Chain F 216–290(75 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 6.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.40 Å
5H30 Cryo-EM structure of zika virus complexed with Fab C10 at pH 6.5 Deposited 2016-10-19 Assembly 4 Protein heterocomplex Heteromer;Protein × 72 PDB declaration: 72-meric(72) Consistent with protein count
Chain A 291–794(504 aa)
Chain B 291–794(504 aa)
Chain C 291–794(504 aa)
Chain D 216–290(75 aa)
Chain E 216–290(75 aa)
Chain F 216–290(75 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 6.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.40 Å
5H30 Cryo-EM structure of zika virus complexed with Fab C10 at pH 6.5 Deposited 2016-10-19 Assembly 5 Protein heterocomplex Heteromer;Protein × 12 PDB declaration: dodecameric(12) Consistent with protein count
Chain A 291–794(504 aa)
Chain B 291–794(504 aa)
Chain C 291–794(504 aa)
Chain D 216–290(75 aa)
Chain E 216–290(75 aa)
Chain F 216–290(75 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 6.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.40 Å
5H30 Cryo-EM structure of zika virus complexed with Fab C10 at pH 6.5 Deposited 2016-10-19 Assembly 6 Protein heterocomplex Heteromer;Protein × 720 PDB declaration: 720-meric(720) Consistent with protein count
Chain A 291–794(504 aa)
Chain B 291–794(504 aa)
Chain C 291–794(504 aa)
Chain D 216–290(75 aa)
Chain E 216–290(75 aa)
Chain F 216–290(75 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 6.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.40 Å
5H32 Cryo-EM structure of zika virus complexed with Fab C10 at pH 5.0 Deposited 2016-10-20 Assembly 1 Protein heterocomplex Heteromer;Protein × 540 PDB declaration: 540-meric(540) Consistent with protein count
Chain A 291–693(403 aa)
Chain B 291–693(403 aa)
Chain C 291–693(403 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 12.00 Å
5H32 Cryo-EM structure of zika virus complexed with Fab C10 at pH 5.0 Deposited 2016-10-20 Assembly 2 Protein heterocomplex Heteromer;Protein × 9 PDB declaration: nonameric(9) Consistent with protein count
Chain A 291–693(403 aa)
Chain B 291–693(403 aa)
Chain C 291–693(403 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 12.00 Å
5H32 Cryo-EM structure of zika virus complexed with Fab C10 at pH 5.0 Deposited 2016-10-20 Assembly 3 Protein heterocomplex Heteromer;Protein × 45 PDB declaration: 45-meric(45) Consistent with protein count
Chain A 291–693(403 aa)
Chain B 291–693(403 aa)
Chain C 291–693(403 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 12.00 Å
5H32 Cryo-EM structure of zika virus complexed with Fab C10 at pH 5.0 Deposited 2016-10-20 Assembly 4 Protein heterocomplex Heteromer;Protein × 54 PDB declaration: 54-meric(54) Consistent with protein count
Chain A 291–693(403 aa)
Chain B 291–693(403 aa)
Chain C 291–693(403 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 12.00 Å
5H32 Cryo-EM structure of zika virus complexed with Fab C10 at pH 5.0 Deposited 2016-10-20 Assembly 5 Protein heterocomplex Heteromer;Protein × 9 PDB declaration: nonameric(9) Consistent with protein count
Chain A 291–693(403 aa)
Chain B 291–693(403 aa)
Chain C 291–693(403 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 12.00 Å
5H32 Cryo-EM structure of zika virus complexed with Fab C10 at pH 5.0 Deposited 2016-10-20 Assembly 6 Protein heterocomplex Heteromer;Protein × 540 PDB declaration: 540-meric(540) Consistent with protein count
Chain A 291–693(403 aa)
Chain B 291–693(403 aa)
Chain C 291–693(403 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 12.00 Å
5H37 Cryo-EM structure of zika virus complexed with Fab C10 at pH 8.0 Deposited 2016-10-20 Assembly 1 Protein heterocomplex Heteromer;Protein × 720 PDB declaration: 720-meric(720) Consistent with protein count
Chain A 291–794(504 aa)
Chain B 291–794(504 aa)
Chain C 291–794(504 aa)
Chain D 216–290(75 aa)
Chain E 216–290(75 aa)
Chain F 216–290(75 aa)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 60 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.00 Å
5H37 Cryo-EM structure of zika virus complexed with Fab C10 at pH 8.0 Deposited 2016-10-20 Assembly 2 Protein heterocomplex Heteromer;Protein × 12 PDB declaration: dodecameric(12) Consistent with protein count
Chain A 291–794(504 aa)
Chain B 291–794(504 aa)
Chain C 291–794(504 aa)
Chain D 216–290(75 aa)
Chain E 216–290(75 aa)
Chain F 216–290(75 aa)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.00 Å
5H37 Cryo-EM structure of zika virus complexed with Fab C10 at pH 8.0 Deposited 2016-10-20 Assembly 3 Protein heterocomplex Heteromer;Protein × 60 PDB declaration: 60-meric(60) Consistent with protein count
Chain A 291–794(504 aa)
Chain B 291–794(504 aa)
Chain C 291–794(504 aa)
Chain D 216–290(75 aa)
Chain E 216–290(75 aa)
Chain F 216–290(75 aa)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 5 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.00 Å
5H37 Cryo-EM structure of zika virus complexed with Fab C10 at pH 8.0 Deposited 2016-10-20 Assembly 4 Protein heterocomplex Heteromer;Protein × 72 PDB declaration: 72-meric(72) Consistent with protein count
Chain A 291–794(504 aa)
Chain B 291–794(504 aa)
Chain C 291–794(504 aa)
Chain D 216–290(75 aa)
Chain E 216–290(75 aa)
Chain F 216–290(75 aa)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 6 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.00 Å
5H37 Cryo-EM structure of zika virus complexed with Fab C10 at pH 8.0 Deposited 2016-10-20 Assembly 5 Protein heterocomplex Heteromer;Protein × 12 PDB declaration: dodecameric(12) Consistent with protein count
Chain A 291–794(504 aa)
Chain B 291–794(504 aa)
Chain C 291–794(504 aa)
Chain D 216–290(75 aa)
Chain E 216–290(75 aa)
Chain F 216–290(75 aa)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.00 Å
5H37 Cryo-EM structure of zika virus complexed with Fab C10 at pH 8.0 Deposited 2016-10-20 Assembly 6 Protein heterocomplex Heteromer;Protein × 720 PDB declaration: 720-meric(720) Consistent with protein count
Chain A 291–794(504 aa)
Chain B 291–794(504 aa)
Chain C 291–794(504 aa)
Chain D 216–290(75 aa)
Chain E 216–290(75 aa)
Chain F 216–290(75 aa)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 60 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.00 Å
5IY3 Zika Virus Non-structural Protein NS1 Deposited 2016-03-23 Assembly 1 Protein homooligomer Homooligomer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count
Chain A 966–1146(181 aa) Fragment:UNP residues 966-1146
Chain B 966–1146(181 aa) Fragment:UNP residues 966-1146
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;293 K;0.09 M NPS mix[NaNO3, Na2HPO4, (NH4)2SO4], 0.1 M buffer mix (Imidazole, Sodium Cacodylate, MES; Bis-Tris) pH 6.5, 37.5% MPD_P1K_P3350 mix(MPD, PEG 1000, PEG 3350)
Resolution 2.20 Å R-free 0.246
5IZ7 Cryo-EM structure of thermally stable Zika virus strain H/PF/2013 Deposited 2016-03-25 Assembly 1 Protein heterocomplex Heteromer;Protein × 360 PDB declaration: 360-meric(360) Consistent with protein count
Chain A 291–794(504 aa)
Chain B 291–794(504 aa)
Chain C 291–794(504 aa)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 180 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE;blot for 1s
Resolution 3.70 Å
5IZ7 Cryo-EM structure of thermally stable Zika virus strain H/PF/2013 Deposited 2016-03-25 Assembly 2 Protein heterocomplex Heteromer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count
Chain A 291–794(504 aa)
Chain B 291–794(504 aa)
Chain C 291–794(504 aa)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 3 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE;blot for 1s
Resolution 3.70 Å
5IZ7 Cryo-EM structure of thermally stable Zika virus strain H/PF/2013 Deposited 2016-03-25 Assembly 3 Protein heterocomplex Heteromer;Protein × 30 PDB declaration: 30-meric(30) Consistent with protein count
Chain A 291–794(504 aa)
Chain B 291–794(504 aa)
Chain C 291–794(504 aa)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 15 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE;blot for 1s
Resolution 3.70 Å
5IZ7 Cryo-EM structure of thermally stable Zika virus strain H/PF/2013 Deposited 2016-03-25 Assembly 4 Protein heterocomplex Heteromer;Protein × 36 PDB declaration: 36-meric(36) Consistent with protein count
Chain A 291–794(504 aa)
Chain B 291–794(504 aa)
Chain C 291–794(504 aa)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 18 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE;blot for 1s
Resolution 3.70 Å
5IZ7 Cryo-EM structure of thermally stable Zika virus strain H/PF/2013 Deposited 2016-03-25 Assembly 5 Protein heterocomplex Heteromer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count
Chain A 291–794(504 aa)
Chain B 291–794(504 aa)
Chain C 291–794(504 aa)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 3 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE;blot for 1s
Resolution 3.70 Å
5JMT Crystal structure of Zika virus NS3 helicase Deposited 2016-04-29 Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain A 1674–2119(446 aa) Fragment:UNP residues 1674-2119
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions MICROBATCH;pH 5.2;291 K;0.1 M Sodium citrate tribasic dihydrate (pH 5.5), 22%(w/v) polyethylene glycol 1000
Resolution 1.80 Å R-free 0.200
5KVD Zika specific antibody, ZV-2, bound to ZIKA envelope DIII Deposited 2016-07-14 Assembly 1 Protein heterocomplex Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count
Chain E 589–697(109 aa) Fragment:UNP residues 589-697
Not recorded NA SODIUM ION × 2 MES 2-(N-MORPHOLINO)-ETHANESULFONIC ACID × 1 EDO 1,2-ETHANEDIOL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 6.5;293 K;0.1 M MES pH6.5, 0.6 M NaCl and 20.6% PEG 4000
Resolution 1.65 Å R-free 0.221
5KVF Zika specific antibody, ZV-64, bound to ZIKA envelope DIII Deposited 2016-07-14 Assembly 1 Protein heterocomplex Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count
Chain E 589–697(109 aa) Fragment:UNP residues 589-697
Not recorded GOL GLYCEROL × 5 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 6.5;293 K;0.1 M sodium acetate and 22% PEG4000
Resolution 1.40 Å R-free 0.186
5KVG Zika specific antibody, ZV-67, bound to ZIKA envelope DIII Deposited 2016-07-14 Assembly 1 Protein heterocomplex Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count
Chain E 589–697(109 aa) Fragment:UNP residues 589-697
Not recorded CL CHLORIDE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;293 K;0.2 M Ammonium formate, 20% PEG 3350
Resolution 1.40 Å R-free 0.179
6CO8 Structure of Zika virus at a resolution of 3.1 Angstrom Deposited 2018-03-12 Assembly 1 Other combination Homooligomer;Protein × 360 PDB declaration: 360-meric(360) Consistent with protein count
Chain A 291–794(504 aa) Fragment:UNP residues 291-794
Chain B 216–290(75 aa) Fragment:UNP residues 216-290
Chain C 291–794(504 aa) Fragment:UNP residues 291-794
Chain D 216–290(75 aa) Fragment:UNP residues 216-290
Chain E 291–794(504 aa) Fragment:UNP residues 291-794
Chain F 216–290(75 aa) Fragment:UNP residues 216-290
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8;12 mM Tris-HCl, pH 8, 120 mM NaCl, 1 mM EDTA
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.10 Å
6CO8 Structure of Zika virus at a resolution of 3.1 Angstrom Deposited 2018-03-12 Assembly 2 Other combination Homooligomer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count
Chain A 291–794(504 aa) Fragment:UNP residues 291-794
Chain B 216–290(75 aa) Fragment:UNP residues 216-290
Chain C 291–794(504 aa) Fragment:UNP residues 291-794
Chain D 216–290(75 aa) Fragment:UNP residues 216-290
Chain E 291–794(504 aa) Fragment:UNP residues 291-794
Chain F 216–290(75 aa) Fragment:UNP residues 216-290
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8;12 mM Tris-HCl, pH 8, 120 mM NaCl, 1 mM EDTA
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.10 Å
6CO8 Structure of Zika virus at a resolution of 3.1 Angstrom Deposited 2018-03-12 Assembly 3 Other combination Homooligomer;Protein × 30 PDB declaration: 30-meric(30) Consistent with protein count
Chain A 291–794(504 aa) Fragment:UNP residues 291-794
Chain B 216–290(75 aa) Fragment:UNP residues 216-290
Chain C 291–794(504 aa) Fragment:UNP residues 291-794
Chain D 216–290(75 aa) Fragment:UNP residues 216-290
Chain E 291–794(504 aa) Fragment:UNP residues 291-794
Chain F 216–290(75 aa) Fragment:UNP residues 216-290
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8;12 mM Tris-HCl, pH 8, 120 mM NaCl, 1 mM EDTA
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.10 Å
6CO8 Structure of Zika virus at a resolution of 3.1 Angstrom Deposited 2018-03-12 Assembly 4 Other combination Homooligomer;Protein × 36 PDB declaration: 36-meric(36) Consistent with protein count
Chain A 291–794(504 aa) Fragment:UNP residues 291-794
Chain B 216–290(75 aa) Fragment:UNP residues 216-290
Chain C 291–794(504 aa) Fragment:UNP residues 291-794
Chain D 216–290(75 aa) Fragment:UNP residues 216-290
Chain E 291–794(504 aa) Fragment:UNP residues 291-794
Chain F 216–290(75 aa) Fragment:UNP residues 216-290
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8;12 mM Tris-HCl, pH 8, 120 mM NaCl, 1 mM EDTA
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.10 Å
6CO8 Structure of Zika virus at a resolution of 3.1 Angstrom Deposited 2018-03-12 Assembly 5 Other combination Homooligomer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count
Chain A 291–794(504 aa) Fragment:UNP residues 291-794
Chain B 216–290(75 aa) Fragment:UNP residues 216-290
Chain C 291–794(504 aa) Fragment:UNP residues 291-794
Chain D 216–290(75 aa) Fragment:UNP residues 216-290
Chain E 291–794(504 aa) Fragment:UNP residues 291-794
Chain F 216–290(75 aa) Fragment:UNP residues 216-290
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8;12 mM Tris-HCl, pH 8, 120 mM NaCl, 1 mM EDTA
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.10 Å
6JFH The asymmetric-reconstructed cryo-EM structure of Zika virus-FabZK2B10 complex Deposited 2019-02-08 Assembly 1 Protein heterocomplex Heteromer;Protein × 12 PDB declaration: dodecameric(12) Consistent with protein count
Chain B 216–290(75 aa)
Chain D 216–290(75 aa)
Chain F 216–290(75 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 20.00 Å
6JFI The symmetric-reconstructed cryo-EM structure of Zika virus-FabZK2B10 complex Deposited 2019-02-08 Assembly 1 Protein heterocomplex Heteromer;Protein × 600 PDB declaration: 600-meric(600) Consistent with protein count
Chain B 216–290(75 aa)
Chain D 216–290(75 aa)
Chain F 216–290(75 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 11.00 Å
6JFI The symmetric-reconstructed cryo-EM structure of Zika virus-FabZK2B10 complex Deposited 2019-02-08 Assembly 2 Protein heterocomplex Heteromer;Protein × 10 PDB declaration: decameric(10) Consistent with protein count
Chain B 216–290(75 aa)
Chain D 216–290(75 aa)
Chain F 216–290(75 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 11.00 Å
6JFI The symmetric-reconstructed cryo-EM structure of Zika virus-FabZK2B10 complex Deposited 2019-02-08 Assembly 3 Protein heterocomplex Heteromer;Protein × 50 PDB declaration: 50-meric(50) Consistent with protein count
Chain B 216–290(75 aa)
Chain D 216–290(75 aa)
Chain F 216–290(75 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 11.00 Å
6JFI The symmetric-reconstructed cryo-EM structure of Zika virus-FabZK2B10 complex Deposited 2019-02-08 Assembly 4 Protein heterocomplex Heteromer;Protein × 60 PDB declaration: 60-meric(60) Consistent with protein count
Chain B 216–290(75 aa)
Chain D 216–290(75 aa)
Chain F 216–290(75 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 11.00 Å
6JFI The symmetric-reconstructed cryo-EM structure of Zika virus-FabZK2B10 complex Deposited 2019-02-08 Assembly 5 Protein heterocomplex Heteromer;Protein × 10 PDB declaration: decameric(10) Consistent with protein count
Chain B 216–290(75 aa)
Chain D 216–290(75 aa)
Chain F 216–290(75 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 11.00 Å
6LD1 Zika NS5 polymerase domain Deposited 2019-11-20 Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain A 2790–3411(622 aa)
Not recorded EDO 1,2-ETHANEDIOL × 3 ZN ZINC ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION;pH 7.5;293 K;10% PEG 6000, 0.2M HEPES pH 7.5
Resolution 1.40 Å R-free 0.218
6LD2 Zika NS5 polymerase domain Deposited 2019-11-20 Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain A 2790–3411(622 aa)
Not recorded ZN ZINC ION × 2 KY3 (1S,2S,4S,5R)-2,4-dimethoxy-5-thiophen-2-yl-cyclohexane-1-carboxylic acid × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION;293 K;10% PEG 6000, 0.2M HEPES pH7.5
Resolution 1.40 Å R-free 0.227
6LD3 Zika NS5 polymerase domain Deposited 2019-11-20 Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain A 2790–3411(622 aa)
Not recorded ZN ZINC ION × 2 G8O 2,4-dimethoxy-5-thiophen-2-yl-benzoic acid × 1 FB2 benzenesulfonamide × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION;293 K;10% PEG 6000, 0.2M HEPES pH 7.5
Resolution 2.30 Å R-free 0.249
6LD4 Zika NS5 polymerase domain Deposited 2019-11-20 Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain A 2790–3411(622 aa)
Not recorded ZN ZINC ION × 2 G8O 2,4-dimethoxy-5-thiophen-2-yl-benzoic acid × 1 G8F 3-methoxybenzenesulfonamide × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION;293 K;10% PEG 6000, 0.2M HEPES pH7.5
Resolution 1.50 Å R-free 0.224
6LD5 Zika NS5 polymerase domain Deposited 2019-11-20 Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain A 2790–3411(622 aa)
Not recorded ZN ZINC ION × 2 G8O 2,4-dimethoxy-5-thiophen-2-yl-benzoic acid × 1 G8L quinoline-8-sulfonamide × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION;293 K;10% PEG 6000, 0.2M HEPES pH 7.4
Resolution 1.94 Å R-free 0.226
6LNT Cryo-EM structure of immature Zika virus in complex with human antibody DV62.5 Fab Deposited 2020-01-02 Assembly 1 Protein heterocomplex Heteromer;Protein × 720 PDB declaration: 720-meric(720) Consistent with protein count
Chain A 291–794(504 aa)
Chain B 291–794(504 aa)
Chain C 291–794(504 aa)
Chain D 128–290(163 aa)
Chain E 128–290(163 aa)
Chain F 128–290(163 aa)
Chain M 6–122(117 aa)
Chain N 6–122(117 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8;10 mM Tris-HCl, 120 mM NaCl, 1 mM EDTA, pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 8.00 Å
6LNT Cryo-EM structure of immature Zika virus in complex with human antibody DV62.5 Fab Deposited 2020-01-02 Assembly 2 Protein heterocomplex Heteromer;Protein × 12 PDB declaration: dodecameric(12) Consistent with protein count
Chain A 291–794(504 aa)
Chain B 291–794(504 aa)
Chain C 291–794(504 aa)
Chain D 128–290(163 aa)
Chain E 128–290(163 aa)
Chain F 128–290(163 aa)
Chain M 6–122(117 aa)
Chain N 6–122(117 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8;10 mM Tris-HCl, 120 mM NaCl, 1 mM EDTA, pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 8.00 Å
6LNT Cryo-EM structure of immature Zika virus in complex with human antibody DV62.5 Fab Deposited 2020-01-02 Assembly 3 Protein heterocomplex Heteromer;Protein × 60 PDB declaration: 60-meric(60) Consistent with protein count
Chain A 291–794(504 aa)
Chain B 291–794(504 aa)
Chain C 291–794(504 aa)
Chain D 128–290(163 aa)
Chain E 128–290(163 aa)
Chain F 128–290(163 aa)
Chain M 6–122(117 aa)
Chain N 6–122(117 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8;10 mM Tris-HCl, 120 mM NaCl, 1 mM EDTA, pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 8.00 Å
6LNT Cryo-EM structure of immature Zika virus in complex with human antibody DV62.5 Fab Deposited 2020-01-02 Assembly 4 Protein heterocomplex Heteromer;Protein × 72 PDB declaration: 72-meric(72) Consistent with protein count
Chain A 291–794(504 aa)
Chain B 291–794(504 aa)
Chain C 291–794(504 aa)
Chain D 128–290(163 aa)
Chain E 128–290(163 aa)
Chain F 128–290(163 aa)
Chain M 6–122(117 aa)
Chain N 6–122(117 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8;10 mM Tris-HCl, 120 mM NaCl, 1 mM EDTA, pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 8.00 Å
6LNT Cryo-EM structure of immature Zika virus in complex with human antibody DV62.5 Fab Deposited 2020-01-02 Assembly 5 Protein heterocomplex Heteromer;Protein × 12 PDB declaration: dodecameric(12) Consistent with protein count
Chain A 291–794(504 aa)
Chain B 291–794(504 aa)
Chain C 291–794(504 aa)
Chain D 128–290(163 aa)
Chain E 128–290(163 aa)
Chain F 128–290(163 aa)
Chain M 6–122(117 aa)
Chain N 6–122(117 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8;10 mM Tris-HCl, 120 mM NaCl, 1 mM EDTA, pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 8.00 Å
6LNU Cryo-EM structure of immature Zika virus Deposited 2020-01-02 Assembly 1 Protein homooligomer Homooligomer;Protein × 360 PDB declaration: 360-meric(360) Consistent with protein count
Chain A 291–794(504 aa)
Chain B 291–794(504 aa)
Chain C 291–794(504 aa)
Chain D 128–290(163 aa)
Chain E 128–290(163 aa)
Chain F 128–290(163 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8;10 mM Tris-HCl, 120 mM NaCl, 1 mM EDTA, pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 9.00 Å
6LNU Cryo-EM structure of immature Zika virus Deposited 2020-01-02 Assembly 2 Protein homooligomer Homooligomer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count
Chain A 291–794(504 aa)
Chain B 291–794(504 aa)
Chain C 291–794(504 aa)
Chain D 128–290(163 aa)
Chain E 128–290(163 aa)
Chain F 128–290(163 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8;10 mM Tris-HCl, 120 mM NaCl, 1 mM EDTA, pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 9.00 Å
6LNU Cryo-EM structure of immature Zika virus Deposited 2020-01-02 Assembly 3 Protein homooligomer Homooligomer;Protein × 30 PDB declaration: 30-meric(30) Consistent with protein count
Chain A 291–794(504 aa)
Chain B 291–794(504 aa)
Chain C 291–794(504 aa)
Chain D 128–290(163 aa)
Chain E 128–290(163 aa)
Chain F 128–290(163 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8;10 mM Tris-HCl, 120 mM NaCl, 1 mM EDTA, pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 9.00 Å
6LNU Cryo-EM structure of immature Zika virus Deposited 2020-01-02 Assembly 4 Protein homooligomer Homooligomer;Protein × 36 PDB declaration: 36-meric(36) Consistent with protein count
Chain A 291–794(504 aa)
Chain B 291–794(504 aa)
Chain C 291–794(504 aa)
Chain D 128–290(163 aa)
Chain E 128–290(163 aa)
Chain F 128–290(163 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8;10 mM Tris-HCl, 120 mM NaCl, 1 mM EDTA, pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 9.00 Å
6LNU Cryo-EM structure of immature Zika virus Deposited 2020-01-02 Assembly 5 Protein homooligomer Homooligomer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count
Chain A 291–794(504 aa)
Chain B 291–794(504 aa)
Chain C 291–794(504 aa)
Chain D 128–290(163 aa)
Chain E 128–290(163 aa)
Chain F 128–290(163 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8;10 mM Tris-HCl, 120 mM NaCl, 1 mM EDTA, pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 9.00 Å
6MID Cryo-EM structure of the ZIKV virion in complex with Fab fragments of the potently neutralizing human monoclonal antibody ZIKV-195 Deposited 2018-09-19 Assembly 1 Other combination Heteromer;Protein × 480 PDB declaration: 480-meric(480) Consistent with protein count
Chain A 291–794(504 aa) Fragment:UNP residues 291-794
Chain B 216–290(75 aa) Fragment:UNP residues 216-290
Chain C 291–794(504 aa) Fragment:UNP residues 291-794
Chain D 216–290(75 aa) Fragment:UNP residues 216-290
Chain E 291–794(504 aa) Fragment:UNP residues 291-794
Chain F 216–290(75 aa) Fragment:UNP residues 216-290
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8;NTE buffer at pH 8.0
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.00 Å
6MID Cryo-EM structure of the ZIKV virion in complex with Fab fragments of the potently neutralizing human monoclonal antibody ZIKV-195 Deposited 2018-09-19 Assembly 2 Other combination Heteromer;Protein × 8 PDB declaration: octameric(8) Consistent with protein count
Chain A 291–794(504 aa) Fragment:UNP residues 291-794
Chain B 216–290(75 aa) Fragment:UNP residues 216-290
Chain C 291–794(504 aa) Fragment:UNP residues 291-794
Chain D 216–290(75 aa) Fragment:UNP residues 216-290
Chain E 291–794(504 aa) Fragment:UNP residues 291-794
Chain F 216–290(75 aa) Fragment:UNP residues 216-290
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8;NTE buffer at pH 8.0
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.00 Å
6MID Cryo-EM structure of the ZIKV virion in complex with Fab fragments of the potently neutralizing human monoclonal antibody ZIKV-195 Deposited 2018-09-19 Assembly 3 Other combination Heteromer;Protein × 40 PDB declaration: 40-meric(40) Consistent with protein count
Chain A 291–794(504 aa) Fragment:UNP residues 291-794
Chain B 216–290(75 aa) Fragment:UNP residues 216-290
Chain C 291–794(504 aa) Fragment:UNP residues 291-794
Chain D 216–290(75 aa) Fragment:UNP residues 216-290
Chain E 291–794(504 aa) Fragment:UNP residues 291-794
Chain F 216–290(75 aa) Fragment:UNP residues 216-290
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8;NTE buffer at pH 8.0
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.00 Å
6MID Cryo-EM structure of the ZIKV virion in complex with Fab fragments of the potently neutralizing human monoclonal antibody ZIKV-195 Deposited 2018-09-19 Assembly 4 Other combination Heteromer;Protein × 48 PDB declaration: 48-meric(48) Consistent with protein count
Chain A 291–794(504 aa) Fragment:UNP residues 291-794
Chain B 216–290(75 aa) Fragment:UNP residues 216-290
Chain C 291–794(504 aa) Fragment:UNP residues 291-794
Chain D 216–290(75 aa) Fragment:UNP residues 216-290
Chain E 291–794(504 aa) Fragment:UNP residues 291-794
Chain F 216–290(75 aa) Fragment:UNP residues 216-290
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8;NTE buffer at pH 8.0
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.00 Å
6MID Cryo-EM structure of the ZIKV virion in complex with Fab fragments of the potently neutralizing human monoclonal antibody ZIKV-195 Deposited 2018-09-19 Assembly 5 Other combination Heteromer;Protein × 8 PDB declaration: octameric(8) Consistent with protein count
Chain A 291–794(504 aa) Fragment:UNP residues 291-794
Chain B 216–290(75 aa) Fragment:UNP residues 216-290
Chain C 291–794(504 aa) Fragment:UNP residues 291-794
Chain D 216–290(75 aa) Fragment:UNP residues 216-290
Chain E 291–794(504 aa) Fragment:UNP residues 291-794
Chain F 216–290(75 aa) Fragment:UNP residues 216-290
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8;NTE buffer at pH 8.0
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.00 Å
6NIP Crystal structure of a human anti-ZIKV-DENV neutralizing antibody MZ1 in complex with ZIKV E glycoprotein Deposited 2018-12-31 Assembly 1 Protein heterocomplex Heteromer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count
Chain E 291–695(405 aa)
Chain Z 291–695(405 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION;pH 6.5;291 K;0.06 M MgCl2, 0.1M Imidazole MES monohydrate (pH 6.5), 20% Ethylene glycol and 10% PEG 8,000
Resolution 4.16 Å R-free 0.237
6NIU Crystal structure of a human anti-ZIKV-DENV neutralizing antibody MZ4 in complex with ZIKV E glycoprotein Deposited 2018-12-31 Assembly 1 Protein heterocomplex Heteromer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count
Chain E 291–695(405 aa)
Chain Z 291–695(405 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 9.5;291 K;1.26 M ammonium sulfate, 0.1 M CHES/NaOH (pH 9.5) and 0.2 M sodium chloride
Resolution 4.30 Å R-free 0.359
6NIU Crystal structure of a human anti-ZIKV-DENV neutralizing antibody MZ4 in complex with ZIKV E glycoprotein Deposited 2018-12-31 Assembly 2 Protein heterocomplex Heteromer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count
Chain A 291–695(405 aa)
Chain B 291–695(405 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 9.5;291 K;1.26 M ammonium sulfate, 0.1 M CHES/NaOH (pH 9.5) and 0.2 M sodium chloride
Resolution 4.30 Å R-free 0.359
7BSD Complex structure of 1G5.3 Fab bound to ZIKV NS1c Deposited 2020-03-30 Assembly 1 Protein heterocomplex Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count
Chain G 966–1146(181 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;291 K;14% v/vPoly(acrylic acid-co-maleic acid) solution
Resolution 2.53 Å R-free 0.239
7BSD Complex structure of 1G5.3 Fab bound to ZIKV NS1c Deposited 2020-03-30 Assembly 2 Protein heterocomplex Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count
Chain I 966–1146(181 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;291 K;14% v/vPoly(acrylic acid-co-maleic acid) solution
Resolution 2.53 Å R-free 0.239
7BU8 Cryo-EM structure of zika virus complexed with Fab SIgN-3C at pH 6.5 Deposited 2020-04-05 Assembly 1 Protein heterocomplex Heteromer;Protein × 720 PDB declaration: 720-meric(720) Consistent with protein count
Chain A 291–794(504 aa)
Chain B 291–794(504 aa)
Chain C 291–794(504 aa)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 180 ELECTRON MICROSCOPY
cryo-EM buffer pH 6.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.80 Å
7BU8 Cryo-EM structure of zika virus complexed with Fab SIgN-3C at pH 6.5 Deposited 2020-04-05 Assembly 2 Protein heterocomplex Heteromer;Protein × 12 PDB declaration: dodecameric(12) Consistent with protein count
Chain A 291–794(504 aa)
Chain B 291–794(504 aa)
Chain C 291–794(504 aa)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 3 ELECTRON MICROSCOPY
cryo-EM buffer pH 6.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.80 Å
7BU8 Cryo-EM structure of zika virus complexed with Fab SIgN-3C at pH 6.5 Deposited 2020-04-05 Assembly 3 Protein heterocomplex Heteromer;Protein × 60 PDB declaration: 60-meric(60) Consistent with protein count
Chain A 291–794(504 aa)
Chain B 291–794(504 aa)
Chain C 291–794(504 aa)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 15 ELECTRON MICROSCOPY
cryo-EM buffer pH 6.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.80 Å
7BU8 Cryo-EM structure of zika virus complexed with Fab SIgN-3C at pH 6.5 Deposited 2020-04-05 Assembly 4 Protein heterocomplex Heteromer;Protein × 72 PDB declaration: 72-meric(72) Consistent with protein count
Chain A 291–794(504 aa)
Chain B 291–794(504 aa)
Chain C 291–794(504 aa)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 18 ELECTRON MICROSCOPY
cryo-EM buffer pH 6.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.80 Å
7BU8 Cryo-EM structure of zika virus complexed with Fab SIgN-3C at pH 6.5 Deposited 2020-04-05 Assembly 5 Protein heterocomplex Heteromer;Protein × 12 PDB declaration: dodecameric(12) Consistent with protein count
Chain A 291–794(504 aa)
Chain B 291–794(504 aa)
Chain C 291–794(504 aa)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 3 ELECTRON MICROSCOPY
cryo-EM buffer pH 6.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.80 Å
7BUA Cryo-EM structure of zika virus complexed with Fab SIgN-3C at pH 8.0 Deposited 2020-04-06 Assembly 1 Protein heterocomplex Heteromer;Protein × 720 PDB declaration: 720-meric(720) Consistent with protein count
Chain A 291–794(504 aa)
Chain B 291–794(504 aa)
Chain C 291–794(504 aa)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 180 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.80 Å
7BUA Cryo-EM structure of zika virus complexed with Fab SIgN-3C at pH 8.0 Deposited 2020-04-06 Assembly 2 Protein heterocomplex Heteromer;Protein × 12 PDB declaration: dodecameric(12) Consistent with protein count
Chain A 291–794(504 aa)
Chain B 291–794(504 aa)
Chain C 291–794(504 aa)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 3 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.80 Å
7BUA Cryo-EM structure of zika virus complexed with Fab SIgN-3C at pH 8.0 Deposited 2020-04-06 Assembly 3 Protein heterocomplex Heteromer;Protein × 60 PDB declaration: 60-meric(60) Consistent with protein count
Chain A 291–794(504 aa)
Chain B 291–794(504 aa)
Chain C 291–794(504 aa)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 15 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.80 Å
7BUA Cryo-EM structure of zika virus complexed with Fab SIgN-3C at pH 8.0 Deposited 2020-04-06 Assembly 4 Protein heterocomplex Heteromer;Protein × 72 PDB declaration: 72-meric(72) Consistent with protein count
Chain A 291–794(504 aa)
Chain B 291–794(504 aa)
Chain C 291–794(504 aa)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 18 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.80 Å
7BUA Cryo-EM structure of zika virus complexed with Fab SIgN-3C at pH 8.0 Deposited 2020-04-06 Assembly 5 Protein heterocomplex Heteromer;Protein × 12 PDB declaration: dodecameric(12) Consistent with protein count
Chain A 291–794(504 aa)
Chain B 291–794(504 aa)
Chain C 291–794(504 aa)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 3 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.80 Å
7CBP CryoEM structure of Zika virus with Fab at 4.1 Angstrom Deposited 2020-06-13 Assembly 1 Other combination Heteromer;Protein × 600 PDB declaration: 600-meric(600) Consistent with protein count
Chain K 291–791(501 aa)
Chain N 291–791(501 aa)
Chain Q 291–791(501 aa)
Chain T 216–290(75 aa)
Chain U 216–290(75 aa)
Chain V 216–290(75 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.10 Å
7CBP CryoEM structure of Zika virus with Fab at 4.1 Angstrom Deposited 2020-06-13 Assembly 2 Other combination Heteromer;Protein × 10 PDB declaration: decameric(10) Consistent with protein count
Chain K 291–791(501 aa)
Chain N 291–791(501 aa)
Chain Q 291–791(501 aa)
Chain T 216–290(75 aa)
Chain U 216–290(75 aa)
Chain V 216–290(75 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.10 Å
7CBP CryoEM structure of Zika virus with Fab at 4.1 Angstrom Deposited 2020-06-13 Assembly 3 Other combination Heteromer;Protein × 50 PDB declaration: 50-meric(50) Consistent with protein count
Chain K 291–791(501 aa)
Chain N 291–791(501 aa)
Chain Q 291–791(501 aa)
Chain T 216–290(75 aa)
Chain U 216–290(75 aa)
Chain V 216–290(75 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.10 Å
7CBP CryoEM structure of Zika virus with Fab at 4.1 Angstrom Deposited 2020-06-13 Assembly 4 Other combination Heteromer;Protein × 60 PDB declaration: 60-meric(60) Consistent with protein count
Chain K 291–791(501 aa)
Chain N 291–791(501 aa)
Chain Q 291–791(501 aa)
Chain T 216–290(75 aa)
Chain U 216–290(75 aa)
Chain V 216–290(75 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.10 Å
7CBP CryoEM structure of Zika virus with Fab at 4.1 Angstrom Deposited 2020-06-13 Assembly 5 Other combination Heteromer;Protein × 10 PDB declaration: decameric(10) Consistent with protein count
Chain K 291–791(501 aa)
Chain N 291–791(501 aa)
Chain Q 291–791(501 aa)
Chain T 216–290(75 aa)
Chain U 216–290(75 aa)
Chain V 216–290(75 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.10 Å
7YAR ZIKV_Fab_G9E Deposited 2022-06-28 Assembly 1 Protein heterocomplex Heteromer;Protein × 720 PDB declaration: 720-meric(720) Consistent with protein count
Chain A 291–794(504 aa)
Chain B 291–794(504 aa)
Chain C 291–794(504 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 5.90 Å
7YAR ZIKV_Fab_G9E Deposited 2022-06-28 Assembly 2 Protein heterocomplex Heteromer;Protein × 12 PDB declaration: dodecameric(12) Consistent with protein count
Chain A 291–794(504 aa)
Chain B 291–794(504 aa)
Chain C 291–794(504 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 5.90 Å
7YAR ZIKV_Fab_G9E Deposited 2022-06-28 Assembly 3 Protein heterocomplex Heteromer;Protein × 60 PDB declaration: 60-meric(60) Consistent with protein count
Chain A 291–794(504 aa)
Chain B 291–794(504 aa)
Chain C 291–794(504 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 5.90 Å
7YAR ZIKV_Fab_G9E Deposited 2022-06-28 Assembly 4 Protein heterocomplex Heteromer;Protein × 72 PDB declaration: 72-meric(72) Consistent with protein count
Chain A 291–794(504 aa)
Chain B 291–794(504 aa)
Chain C 291–794(504 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 5.90 Å
7YAR ZIKV_Fab_G9E Deposited 2022-06-28 Assembly 5 Protein heterocomplex Heteromer;Protein × 12 PDB declaration: dodecameric(12) Consistent with protein count
Chain A 291–794(504 aa)
Chain B 291–794(504 aa)
Chain C 291–794(504 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 5.90 Å
8EE5 Crystal structure of a NHP anti-ZIKV neutralizing antibody rhMZ119-D in complex with ZIKV E glycoprotein Deposited 2022-09-06 Assembly 1 Other combination Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count
Chain Z 291–695(405 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;291 K;0.06M Nitrate Phosphate Sulfate , 0.1M Sodium HEPES and MOPS (acid) pH 7.5, 20% Ethylene glycol, 10 % PEG 8000 + 2% w/v Benzamidine hydrochloride
Resolution 3.58 Å R-free 0.296
8EE8 Crystal structure of a NHP anti-ZIKV neutralizing antibody rhMZ100-C in complex with ZIKV E glycoprotein Deposited 2022-09-06 Assembly 1 Protein heterocomplex Heteromer;Protein × 8 PDB declaration: octameric(8) Consistent with protein count
Chain A 291–695(405 aa)
Chain B 291–695(405 aa)
Chain E 291–695(405 aa)
Chain Z 291–695(405 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;291 K;12% PEG 8000, 0.2 M (NH4)2SO4, 0.1M Tris (pH 8.5)
Resolution 2.80 Å R-free 0.295
8EED Crystal structure of a NHP anti-ZIKV neutralizing antibody rhMZ107-B in complex with ZIKV E glycoprotein Deposited 2022-09-07 Assembly 1 Protein heterocomplex Heteromer;Protein × 12 PDB declaration: dodecameric(12) Consistent with protein count
Chain A 291–695(405 aa)
Chain B 291–695(405 aa)
Chain C 291–695(405 aa)
Chain D 291–695(405 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;291 K;15% PEG 6000, 5% MPD, 0.1 M MES (pH 6.5)
Resolution 3.49 Å R-free 0.331
8EEE Crystal structure of a NHP anti-ZIKV neutralizing antibody rhMZ104-d in complex with ZIKV E glycoprotein Deposited 2022-09-07 Assembly 1 Protein heterocomplex Heteromer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count
Chain E 291–695(405 aa)
Chain Z 291–695(405 aa)
Not recorded SO4 SULFATE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;291 K;12% PEG 8000, 0.2 M (NH4)2SO4, 0.1M Tris-HCl (pH 8.5)
Resolution 2.82 Å R-free 0.275
9JS6 cryoEM of antibody complexed with immature Zika virus Deposited 2024-09-30 Assembly 1 Protein heterocomplex Heteromer;Protein × 480 PDB declaration: 480-meric(480) Consistent with protein count
Chain A 292–794(503 aa)
Chain B 292–794(503 aa)
Chain C 292–794(503 aa)
Chain D 128–290(163 aa)
Chain E 128–290(163 aa)
Chain F 128–290(163 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 7.80 Å
9JS6 cryoEM of antibody complexed with immature Zika virus Deposited 2024-09-30 Assembly 2 Protein heterocomplex Heteromer;Protein × 8 PDB declaration: octameric(8) Consistent with protein count
Chain A 292–794(503 aa)
Chain B 292–794(503 aa)
Chain C 292–794(503 aa)
Chain D 128–290(163 aa)
Chain E 128–290(163 aa)
Chain F 128–290(163 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 7.80 Å
9JS6 cryoEM of antibody complexed with immature Zika virus Deposited 2024-09-30 Assembly 3 Protein heterocomplex Heteromer;Protein × 40 PDB declaration: 40-meric(40) Consistent with protein count
Chain A 292–794(503 aa)
Chain B 292–794(503 aa)
Chain C 292–794(503 aa)
Chain D 128–290(163 aa)
Chain E 128–290(163 aa)
Chain F 128–290(163 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 7.80 Å
9JS6 cryoEM of antibody complexed with immature Zika virus Deposited 2024-09-30 Assembly 4 Protein heterocomplex Heteromer;Protein × 48 PDB declaration: 48-meric(48) Consistent with protein count
Chain A 292–794(503 aa)
Chain B 292–794(503 aa)
Chain C 292–794(503 aa)
Chain D 128–290(163 aa)
Chain E 128–290(163 aa)
Chain F 128–290(163 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 7.80 Å
9JS6 cryoEM of antibody complexed with immature Zika virus Deposited 2024-09-30 Assembly 5 Protein heterocomplex Heteromer;Protein × 8 PDB declaration: octameric(8) Consistent with protein count
Chain A 292–794(503 aa)
Chain B 292–794(503 aa)
Chain C 292–794(503 aa)
Chain D 128–290(163 aa)
Chain E 128–290(163 aa)
Chain F 128–290(163 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 7.80 Å
9JS7 cryoEM of antibody complexed with mature Zika virus Deposited 2024-09-30 Assembly 1 Protein heterocomplex Heteromer;Protein × 420 PDB declaration: 420-meric(420) Consistent with protein count
Chain A 291–794(504 aa)
Chain B 291–794(504 aa)
Chain C 291–794(504 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.84 Å
9JS7 cryoEM of antibody complexed with mature Zika virus Deposited 2024-09-30 Assembly 2 Protein heterocomplex Heteromer;Protein × 7 PDB declaration: heptameric(7) Consistent with protein count
Chain A 291–794(504 aa)
Chain B 291–794(504 aa)
Chain C 291–794(504 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.84 Å
9JS7 cryoEM of antibody complexed with mature Zika virus Deposited 2024-09-30 Assembly 3 Protein heterocomplex Heteromer;Protein × 35 PDB declaration: 35-meric(35) Consistent with protein count
Chain A 291–794(504 aa)
Chain B 291–794(504 aa)
Chain C 291–794(504 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.84 Å
9JS7 cryoEM of antibody complexed with mature Zika virus Deposited 2024-09-30 Assembly 4 Protein heterocomplex Heteromer;Protein × 42 PDB declaration: 42-meric(42) Consistent with protein count
Chain A 291–794(504 aa)
Chain B 291–794(504 aa)
Chain C 291–794(504 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.84 Å
9JS7 cryoEM of antibody complexed with mature Zika virus Deposited 2024-09-30 Assembly 5 Protein heterocomplex Heteromer;Protein × 7 PDB declaration: heptameric(7) Consistent with protein count
Chain A 291–794(504 aa)
Chain B 291–794(504 aa)
Chain C 291–794(504 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.84 Å
9OD2 Cryo-EM structure of modified Zika virus E protein dimer complexed with a neutralizing antibody SMZAb2 Fab Deposited 2025-04-25 Assembly 1 Protein heterocomplex Heteromer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count
Chain A 290–695(406 aa)
Chain B 290–695(406 aa)
Mutation:G5C, G102C Mutation:G5C, G102C No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.09 Å
9XYB Crystal structure of a ZIKV E glycoprotein DI-DIII vaccine candidate in complex with human neutralizing antibody MZ4 Deposited 2025-08-25 Assembly 1 Protein heterocomplex Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count
Chain E 291–342(52 aa)
Chain E 425–486(62 aa)
Chain E 576–695(120 aa)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;291 K;40% (v/v) pentaerythritol propoxylate (5/4 PO/OH), 15% (v/v) ethanol
Resolution 2.85 Å R-free 0.316