Current Protein Identity：P02754
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 1B0O BOVINE BETA-LACTOGLOBULIN COMPLEXED WITH PALMITATE, LATTICE Z Deposited 1998-11-11 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
17–178（162 aa）
|
Not recorded | PLM PALMITIC ACID × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 7.5；pH 7.5
|
Resolution 2.50 Å R-free 0.240 |
| 1B8E HIGH RESOLUTION CRYSTAL STRUCTURE OF THE BOVINE BETA-LACTOGLOBULIN (ISOFORMS A AND B) IN ORTHOROMBIC SPACE GROUP Deposited 1999-01-30 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
17–178（162 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.9；METHOD IN PRESENCE OF AMMONIUM SULPHATE 2.5 M, 180MM TRIZMA BUFFER AT A PROTEIN CONCENTRATION OF 20MG/ML, pH 7.9, VAPOR DIFFUSION, HANGING DROP
|
Resolution 1.95 Å R-free 0.252 |
| 1BEB BOVINE BETA-LACTOGLOBULIN, LATTICE X Deposited 1996-12-20 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
17–178（162 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
batch method；pH 6.5；25MG/ML PROTEIN WAS DISSOLVED IN 0.1M SODIUM/ POTASSIUM PHOSPHATE BUFFER (PH 7.0) AND CRYSTALLIZED BY THE BATCH METHOD FROM 2M AMMONIUM SULFATE (PH 6.5) AND 0.4M SODIUM/POTASSIUM PHOSPHATE BUFFER (PH 7.6)., batch method
|
Resolution 1.80 Å R-free 0.243 |
| 1BEB BOVINE BETA-LACTOGLOBULIN, LATTICE X Deposited 1996-12-20 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
17–178（162 aa）
|
Not recorded | SO4 SULFATE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
batch method；pH 6.5；25MG/ML PROTEIN WAS DISSOLVED IN 0.1M SODIUM/ POTASSIUM PHOSPHATE BUFFER (PH 7.0) AND CRYSTALLIZED BY THE BATCH METHOD FROM 2M AMMONIUM SULFATE (PH 6.5) AND 0.4M SODIUM/POTASSIUM PHOSPHATE BUFFER (PH 7.6)., batch method
|
Resolution 1.80 Å R-free 0.243 |
| 1BSO 12-BROMODODECANOIC ACID BINDS INSIDE THE CALYX OF BOVINE BETA-LACTOGLOBULIN Deposited 1998-08-29 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
17–178（162 aa）
|
Not recorded | BRC 12-BROMODODECANOIC ACID × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 7.3；PROTEIN WAS CRYSTALLIZED FROM AMMONIUM SULFATE, pH 7.3
|
Resolution 2.23 Å R-free 0.276 |
| 1BSQ STRUCTURAL AND FUNCTIONAL CONSEQUENCES OF POINT MUTATIONS OF VARIANTS A AND B OF BOVINE BETA-LACTOGLOBULIN Deposited 1998-08-29 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
17–178（162 aa）
|
Mutation：VARIANT B | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 7.1；PROTEIN WAS CRYSTALLIZED FROM AMMONIUM SULFATE; PH 7.1
|
Resolution 2.22 Å R-free 0.286 |
| 1BSY STRUCTURAL BASIS OF THE TANFORD TRANSITION OF BOVINE BETA-LACTOGLOBULIN FROM CRYSTAL STRUCTURES AT THREE PH VALUES; PH 7.1 Deposited 1998-08-31 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
17–178（162 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 7.1；pH 7.1
|
Resolution 2.24 Å R-free 0.279 |
| 1CJ5 BOVINE BETA-LACTOGLOBULIN A Deposited 1999-04-22 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
19–178（160 aa）
|
Mutation：VARIANT A (LEU1-ILE2-VAL3 WAS MODIFIED TO GLU(-3)-ALA(-2)-GLU(-1)-ALA1-TYR2- VAL3) ) | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 2；318 K；Ionic strength (raw mmCIF value) 0.02；Pressure 1
NMR sample composition
5% WATER/95% D2O
|
Resolution not provided |
| 1DV9 STRUCTURAL CHANGES ACCOMPANYING PH-INDUCED DISSOCIATION OF THE B-LACTOGLOBULIN DIMER Deposited 2000-01-20 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
17–178（162 aa）
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 2.7；310 K；Ionic strength (raw mmCIF value) not known；Pressure ambient
NMR sample composition
1mM B-lactoglobuline-15N,13C; 50mM phosphate buffer; 90% H2O, 10% D2O | 90% H2O/10% D2O
|
Resolution not provided |
| 1GX8 BOVINE BETA-LACTOGLOBULIN COMPLEXED WITH RETINOL, TRIGONAL LATTICE Z Deposited 2002-03-29 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
17–178（162 aa）
|
Not recorded | RTL RETINOL × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 7.3；290 K；17 DEG C, 8MUL BLG-RET COMPLEX 20MM TRIS, PH 8 + 8MUL NA CITRATE 1.25M, 0.1M HEPES, PH7.3 DROP
|
Resolution 2.40 Å R-free 0.306 |
| 1GX9 BOVINE BETA-LACTOGLOBULIN COMPLEXED WITH RETINOIC ACID, TRIGONAL LATTICE Z Deposited 2002-03-29 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
17–178（162 aa）
|
Not recorded | REA RETINOIC ACID × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 7.3；290 K；17 DEG C, 8MUL BLG-RET COMPLEX 20MM TRIS, PH 8 + 8MUL NA CITRATE 1.25M, 0.1M HEPES, PH7.3, PER DROP
|
Resolution 2.34 Å R-free 0.298 |
| 1GXA BOVINE BETA-LACTOGLOBULIN COMPLEXED WITH RETINOL AND PALMITIC ACID, TRIGONAL LATTICE Z Deposited 2002-04-01 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
17–178（162 aa）
|
Not recorded | PLM PALMITIC ACID × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 7.3；290 K；17 DEG C, 8MUL BLG-RET-PLM COMPLEX 20MM TRIS, PH 8 + 8MUL NA CITRATE 1.25M, 0.1M HEPES, PH7.3, PER DROP
|
Resolution 2.35 Å R-free 0.301 |
| 1QG5 HIGH RESOLUTION CRYSTAL STRUCTURE OF THE BOVINE BETA-LACTOGLOBULIN (ISOFORM A) Deposited 1999-04-20 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
17–178（162 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.9；THE CRYSTAL WAS GROWN AT PH 7.9, HANGING DROP METHOD. DROP CONTAINED 2.5M (NH4)
2SO4, 180MM TRIZMA BUFFER, AND 20MG/ML PROTEIN REMARK 290, VAPOR DIFFUSION, HANGING DROP
|
Resolution 2.00 Å R-free 0.287 |
| 1UZ2 The Cys121Ser Mutant of Beta-Lactoglobulin Deposited 2004-03-03 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain X
17–178（162 aa）
|
Mutation：YES | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；HANGING DROPS WITH 20 MG/ML PROTEIN PLUS APPROX 2M AMMONIUM SULPHATE, 10MM HEPES, PH 7.5
|
Resolution 1.95 Å R-free 0.267 |
| 2AKQ The structure of bovine B-lactoglobulin A in crystals grown at very low ionic strength Deposited 2005-08-03 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
17–178（162 aa）
Chain B
17–178（162 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
MICRODIALYSIS；pH 5.2；295 K；Ultra pure water, pH 5.20, MICRODIALYSIS, temperature 295K
|
Resolution 3.00 Å R-free 0.266 |
| 2AKQ The structure of bovine B-lactoglobulin A in crystals grown at very low ionic strength Deposited 2005-08-03 | Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain C
17–178（162 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
MICRODIALYSIS；pH 5.2；295 K；Ultra pure water, pH 5.20, MICRODIALYSIS, temperature 295K
|
Resolution 3.00 Å R-free 0.266 |
| 2AKQ The structure of bovine B-lactoglobulin A in crystals grown at very low ionic strength Deposited 2005-08-03 | Assembly 3 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain D
17–178（162 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
MICRODIALYSIS；pH 5.2；295 K；Ultra pure water, pH 5.20, MICRODIALYSIS, temperature 295K
|
Resolution 3.00 Å R-free 0.266 |
| 2BLG STRUCTURAL BASIS OF THE TANFORD TRANSITION OF BOVINE BETA-LACTOGLOBULIN FROM CRYSTAL STRUCTURES AT THREE PH VALUES; PH 8.2 Deposited 1998-08-29 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
17–178（162 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 8.2；pH 8.2
|
Resolution 2.46 Å R-free 0.277 |
| 2GJ5 Crystal structure of a secondary vitamin D3 binding site of milk beta-lactoglobulin Deposited 2006-03-30 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
17–178（162 aa）
|
Not recorded | VD3 (1S,3Z)-3-[(2E)-2-[(1R,3AR,7AS)-7A-METHYL-1-[(2R)-6-METHYLHEPTAN-2-YL]-2,3,3A,5,6,7-HEXAHYDRO-1H-INDEN-4-YLIDENE]ETHYLI DENE]-4-METHYLIDENE-CYCLOHEXAN-1-OL × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；293 K；0.1M HEPES, 1.4M tri-sodium citrate dehydrate, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 2.40 Å R-free 0.298 |
| 2Q2M Beta-lactoglobulin (native) Deposited 2007-05-29 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
17–178（162 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.4；293 K；0.01M hepes, 2.2 to 2.8 M Ammonium sulphate, NAOH, pH 7.40, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 2.10 Å R-free 0.268 |
| 2Q2P Beta-lactoglobulin (reverse native) Deposited 2007-05-29 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
17–178（162 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.4；293 K；0.01M Hepes, 2.2 to 2.8 M Ammonium sulphate, NAOH, pH 7.40, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 2.96 Å R-free 0.242 |
| 2Q39 Beta-lactoglobulin (low humidity) Deposited 2007-05-30 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
17–178（162 aa）
Chain B
17–178（162 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.4；293 K；0.01M hepes, 2.2 to 2.8 M Ammonium sulphate, NAOH, pH 7.40, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 2.50 Å R-free 0.306 |
| 2R56 Crystal Structure of a Recombinant IgE Fab Fragment in Complex with Bovine Beta-Lactoglobulin Allergen Deposited 2007-09-03 | Assembly 1 Protein heterocomplex Heteromer；Protein × 6 PDB declaration: hexameric（6） Consistent with protein count |
Chain A
17–178（162 aa）
Chain B
17–178（162 aa）
|
Not recorded | LMT DODECYL-BETA-D-MALTOSIDE × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 5.5；293 K；14 % PEG3350, 0.1 M BTP, n-dodecyl-beta-D-maltoside, pH 5.5, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 2.80 Å R-free 0.291 |
| 3BLG STRUCTURAL BASIS OF THE TANFORD TRANSITION OF BOVINE BETA-LACTOGLOBULIN FROM CRYSTAL STRUCTURES AT THREE PH VALUES; PH 6.2 Deposited 1998-08-29 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
17–178（162 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 6.2；pH 6.2
|
Resolution 2.56 Å R-free 0.240 |
| 3KZA Crystal structure of Gyuba, a patched chimera of b-lactglobulin Deposited 2009-12-08 | Assembly 1 Insufficient information Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
33–43（11 aa）
Chain A
58–65（8 aa）
Chain A
68–78（11 aa）
Chain A
82–89（8 aa）
Chain A
96–102（7 aa）
Chain A
105–111（7 aa）
Chain A
118–124（7 aa）
Chain A
133–140（8 aa）
Chain A
146–154（9 aa）
Chain A
161–169（9 aa）
Chain B
33–43（11 aa）
Chain B
58–65（8 aa）
Chain B
68–78（11 aa）
Chain B
82–89（8 aa）
Chain B
96–102（7 aa）
Chain B
105–111（7 aa）
Chain B
118–124（7 aa）
Chain B
133–140（8 aa）
Chain B
146–154（9 aa）
Chain B
161–169（9 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7；293 K；2.0M ammonium sulfate, pH 7.0, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 2.00 Å R-free 0.285 |
| 3KZA Crystal structure of Gyuba, a patched chimera of b-lactglobulin Deposited 2009-12-08 | Assembly 2 Insufficient information Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
33–43（11 aa）
Chain A
58–65（8 aa）
Chain A
68–78（11 aa）
Chain A
82–89（8 aa）
Chain A
96–102（7 aa）
Chain A
105–111（7 aa）
Chain A
118–124（7 aa）
Chain A
133–140（8 aa）
Chain A
146–154（9 aa）
Chain A
161–169（9 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7；293 K；2.0M ammonium sulfate, pH 7.0, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 2.00 Å R-free 0.285 |
| 3KZA Crystal structure of Gyuba, a patched chimera of b-lactglobulin Deposited 2009-12-08 | Assembly 3 Insufficient information Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
33–43（11 aa）
Chain B
58–65（8 aa）
Chain B
68–78（11 aa）
Chain B
82–89（8 aa）
Chain B
96–102（7 aa）
Chain B
105–111（7 aa）
Chain B
118–124（7 aa）
Chain B
133–140（8 aa）
Chain B
146–154（9 aa）
Chain B
161–169（9 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7；293 K；2.0M ammonium sulfate, pH 7.0, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 2.00 Å R-free 0.285 |
| 3NPO Bovine beta lactoglobulin unliganded form Deposited 2010-06-28 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
17–178（162 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；293 K；1.34M trisodium citrate, 0.1M Tris-HCl buffer, 96% ethanol, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 293.0K
|
Resolution 2.20 Å R-free 0.260 |
| 3NQ3 Bovine beta-lactoglobulin complex with capric acid Deposited 2010-06-29 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
17–178（162 aa）
|
Not recorded | DKA DECANOIC ACID × 1 GOL GLYCEROL × 1 CL CHLORIDE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；293 K；1.34M trisodium citrate, 0.1M Tris-HCl buffer, 1mM capric acid in 96% ethanol , pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 1.90 Å R-free 0.289 |
| 3NQ9 Bovine beta-lactoglobulin complex with caprylic acid Deposited 2010-06-29 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
17–178（162 aa）
|
Not recorded | OCA OCTANOIC ACID (CAPRYLIC ACID) × 1 CL CHLORIDE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；293 K；1.34M trisodium citrate, 0.1M Tris-HCl buffer, 10mM caprylic acid in 96% ethanol , pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 1.90 Å R-free 0.309 |
| 3PH5 Bovine beta lactoglobulin crystallized through ligandation of yttrium cations Deposited 2010-11-03 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
18–178（161 aa）
Fragment：unp residues 18-178
|
Not recorded | YT3 YTTRIUM (III) ION × 2 CL CHLORIDE ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
Batch Crystallization；pH 7；277 K；Crystallized in presents of 3.0 mM yttrium(III) chlorid, pH 7, Batch Crystallization, temperature 277K
|
Resolution 2.40 Å R-free 0.263 |
| 3PH5 Bovine beta lactoglobulin crystallized through ligandation of yttrium cations Deposited 2010-11-03 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
18–178（161 aa）
Fragment：unp residues 18-178
|
Not recorded | YT3 YTTRIUM (III) ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
Batch Crystallization；pH 7；277 K；Crystallized in presents of 3.0 mM yttrium(III) chlorid, pH 7, Batch Crystallization, temperature 277K
|
Resolution 2.40 Å R-free 0.263 |
| 3PH6 Bovine beta lactoglobulin crytsallized through ligandation of yttrium Deposited 2010-11-03 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
18–178（161 aa）
Fragment：unp residues 18-178
|
Not recorded | YT3 YTTRIUM (III) ION × 2 CL CHLORIDE ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
Batch crystallization；pH 7；277 K；0.3 mM Yttrium, pH 7, Batch crystallization, temperature 277K
|
Resolution 2.53 Å R-free 0.265 |
| 3PH6 Bovine beta lactoglobulin crytsallized through ligandation of yttrium Deposited 2010-11-03 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
18–178（161 aa）
Fragment：unp residues 18-178
|
Not recorded | YT3 YTTRIUM (III) ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
Batch crystallization；pH 7；277 K；0.3 mM Yttrium, pH 7, Batch crystallization, temperature 277K
|
Resolution 2.53 Å R-free 0.265 |
| 3UEU Bovine beta-lactoglobulin complex with lauric acid Deposited 2011-10-31 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
17–178（162 aa）
|
Not recorded | DAO LAURIC ACID × 2 CL CHLORIDE ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；293 K；1.34 M trisodium citrarte, 0.1 Tris-HCl buffer, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 2.10 Å R-free 0.255 |
| 3UEV Bovine beta-lactoglobulin complex with myristic acid Deposited 2011-10-31 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
17–178（162 aa）
|
Not recorded | MYR MYRISTIC ACID × 2 GOL GLYCEROL × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；293 K；1.34 M trisodium citrate, 0.1 M Tris-HCl buffer, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 1.90 Å R-free 0.275 |
| 3UEV Bovine beta-lactoglobulin complex with myristic acid Deposited 2011-10-31 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
17–178（162 aa）
|
Not recorded | MYR MYRISTIC ACID × 1 GOL GLYCEROL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；293 K；1.34 M trisodium citrate, 0.1 M Tris-HCl buffer, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 1.90 Å R-free 0.275 |
| 3UEW Bovine beta-lactoglobulin complex with palmitic acid Deposited 2011-10-31 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
17–178（162 aa）
|
Not recorded | PLM PALMITIC ACID × 2 EOH ETHANOL × 6 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；293 K；1.34 M trisodium citrate, 0.1 M Tris-HCl buffer, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 2.00 Å R-free 0.266 |
| 3UEW Bovine beta-lactoglobulin complex with palmitic acid Deposited 2011-10-31 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
17–178（162 aa）
|
Not recorded | PLM PALMITIC ACID × 1 EOH ETHANOL × 3 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；293 K；1.34 M trisodium citrate, 0.1 M Tris-HCl buffer, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 2.00 Å R-free 0.266 |
| 3UEX Bovine beta-lactoglobulin complex with stearic acid Deposited 2011-10-31 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
17–178（162 aa）
|
Not recorded | STE STEARIC ACID × 2 EOH ETHANOL × 6 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；293 K；1.34 M trisodium citrarte, 0.1 Tris-HCl buffer, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 239K, temperature 293K
|
Resolution 2.10 Å R-free 0.284 |
| 3UEX Bovine beta-lactoglobulin complex with stearic acid Deposited 2011-10-31 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
17–178（162 aa）
|
Not recorded | STE STEARIC ACID × 1 EOH ETHANOL × 3 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；293 K；1.34 M trisodium citrarte, 0.1 Tris-HCl buffer, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 239K, temperature 293K
|
Resolution 2.10 Å R-free 0.284 |
| 4DQ3 Bovine beta-lactoglobulin complex with oleic acid Deposited 2012-02-15 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
17–178（162 aa）
Fragment：UNP residues 17-178
|
Not recorded | OLA OLEIC ACID × 2 EOH ETHANOL × 2 GOL GLYCEROL × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；293 K；0.1M Tris-HCl buffer, 1.34M tri-sodium citrate, 1mM oleic acid in ethanol, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 2.10 Å R-free 0.289 |
| 4DQ3 Bovine beta-lactoglobulin complex with oleic acid Deposited 2012-02-15 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
17–178（162 aa）
Fragment：UNP residues 17-178
|
Not recorded | OLA OLEIC ACID × 1 EOH ETHANOL × 1 GOL GLYCEROL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；293 K；0.1M Tris-HCl buffer, 1.34M tri-sodium citrate, 1mM oleic acid in ethanol, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 2.10 Å R-free 0.289 |
| 4DQ4 Bovine beta-lactoglobulin complex with linoleic acid Deposited 2012-02-15 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
17–178（162 aa）
Fragment：UNP residues 17-178
|
Not recorded | EIC LINOLEIC ACID × 2 GOL GLYCEROL × 2 EOH ETHANOL × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；293 K；0.1M Tris-HCl buffer, 1.34M tri-sodium citrate, 1mM linoleic acid in ethanol, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 2.10 Å R-free 0.290 |
| 4DQ4 Bovine beta-lactoglobulin complex with linoleic acid Deposited 2012-02-15 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
17–178（162 aa）
Fragment：UNP residues 17-178
|
Not recorded | EIC LINOLEIC ACID × 1 GOL GLYCEROL × 1 EOH ETHANOL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；293 K；0.1M Tris-HCl buffer, 1.34M tri-sodium citrate, 1mM linoleic acid in ethanol, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 2.10 Å R-free 0.290 |
| 4GNY Bovine beta-lactoglobulin complex with dodecyl sulfate Deposited 2012-08-17 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
17–178（162 aa）
|
Not recorded | SDS DODECYL SULFATE × 2 GOL GLYCEROL × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.4；291 K；1.34 M trisodium citrate in 0.05 M Tris-HCl buffer, pH 7.4, VAPOR DIFFUSION, HANGING DROP, temperature 291K
|
Resolution 1.64 Å R-free 0.226 |
| 4IB6 Bovine beta-lactoglobulin (isoform A) in complex with lauric acid (C12) Deposited 2012-12-08 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
17–178（162 aa）
Fragment：UNP residues 17-178
|
Not recorded | DAO LAURIC ACID × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；293 K；1.34M TRISODIUM CITRATE, 0.1M TRIS-HCL BUFFER, PH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 2.20 Å R-free 0.268 |
| 4IB7 Bovine beta-lactoglobulin (isoform A) in complex with dodecyltrimethylammonium (DTAC) Deposited 2012-12-08 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
17–178（162 aa）
Fragment：UNP residues 17-178
|
Not recorded | CAT DODECANE-TRIMETHYLAMINE × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；293 K；1.34M TRISODIUM CITRATE, 0.1M TRIS-HCL BUFFER, PH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 2.20 Å R-free 0.309 |
| 4IB8 Bovine beta-lactoglobulin (isoform A) in complex with dodecyl sulphate (SDS) Deposited 2012-12-08 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
17–178（162 aa）
Fragment：UNP residues 17-178
|
Not recorded | SDS DODECYL SULFATE × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；293 K；1.34M TRISODIUM CITRATE, 0.1M TRIS-HCL BUFFER, PH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 2.30 Å R-free 0.285 |
| 4IB9 Bovine beta-lactoglobulin (isoform B) in complex with dodecyltrimethylammonium (DTAC) Deposited 2012-12-08 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
17–178（162 aa）
Fragment：UNP residues 17-178
|
Not recorded | CAT DODECANE-TRIMETHYLAMINE × 2 GOL GLYCEROL × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；293 K；1.34M TRISODIUM CITRATE, 0.1M TRIS-HCL BUFFER, PH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 2.20 Å R-free 0.306 |
| 4IB9 Bovine beta-lactoglobulin (isoform B) in complex with dodecyltrimethylammonium (DTAC) Deposited 2012-12-08 | Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
17–178（162 aa）
Fragment：UNP residues 17-178
|
Not recorded | CAT DODECANE-TRIMETHYLAMINE × 2 GOL GLYCEROL × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；293 K；1.34M TRISODIUM CITRATE, 0.1M TRIS-HCL BUFFER, PH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 2.20 Å R-free 0.306 |
| 4IBA Bovine beta-lactoglobulin (isoform B) in complex with dodecyl sulphate (SDS) Deposited 2012-12-08 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
17–178（162 aa）
Fragment：UNP residues 17-178
|
Not recorded | SDS DODECYL SULFATE × 2 GOL GLYCEROL × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；293 K；1.34M TRISODIUM CITRATE, 0.1M TRIS-HCL BUFFER, PH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 2.30 Å R-free 0.281 |
| 4KII Beta-lactoglobulin in complex with Cp*Rh(III)Cl N,N-di(pyridin-2-yl)dodecanamide Deposited 2013-05-02 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
17–178（162 aa）
|
Not recorded | RHL [N,N-di(pyridin-2-yl-kappaN)dodecanamide]rhodium × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；293 K；1.44 M trisodium citrate
100 mM Tris HCl pH 7.5 , VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 1.85 Å R-free 0.220 |
| 4LZU Bovine beta-lactoglobulin crystallized in the presence of 2 mM zinc chloride Deposited 2013-08-01 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
17–178（162 aa）
Fragment：UNP residues 17-178
|
Not recorded | ZN ZINC ION × 4 | X-RAY DIFFRACTION |
X-ray crystallization conditions
BATCH；pH 6；277 K；2 mM zinc chloride, pH 6.0, BATCH, temperature 277K
|
Resolution 2.40 Å R-free 0.231 |
| 4LZV Bovine beta-lactoglobulin crystallized in the presence of 20 mM zinc chloride Deposited 2013-08-01 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
17–178（162 aa）
Fragment：UNP residues 17-178
|
Not recorded | ZN ZINC ION × 6 | X-RAY DIFFRACTION |
X-ray crystallization conditions
BATCH；pH 5.9；277 K；20 mM zinc chloride, pH 5.9, BATCH, temperature 277K
|
Resolution 2.44 Å R-free 0.233 |
| 4Y0P Bovine beta-lactoglobulin complex with tetracaine (BLG-TET) Deposited 2015-02-06 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
17–178（162 aa）
Fragment：UNP RESIDUES 17-178
|
Not recorded | TE4 Tetracaine × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；293 K；protein 20 mg/ml, 1.34 M sodium citrate in 0.1 M Tris-HCl pH 7.5 and 5 mM tetracaine
|
Resolution 2.20 Å R-free 0.265 |
| 4Y0Q Bovine beta-lactoglobulin complex with pramocaine crystallized from sodium citrate (BLG-PRM1) Deposited 2015-02-06 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
17–178（162 aa）
|
Not recorded | PX9 Pramocaine × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；293 K；protein 20 mg/ml, 1.34 M sodium citrate in 0.1 M Tris-HCl pH 7.5
|
Resolution 2.00 Å R-free 0.278 |
| 4Y0R Bovine beta-lactoglobulin complex with pramocaine crystallized from ammonium sulphate (BLG-PRM2) Deposited 2015-02-06 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
17–178（162 aa）
Fragment：unp residues 17-178
|
Not recorded | PX9 Pramocaine × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；293 K；protein 20 mg/ml, 2.4 M (NH4)2SO4 in 0.5 M Tris-HCl pH 8.9 and 5 mM pramociane
|
Resolution 2.30 Å R-free 0.285 |
| 5HTD Recombinant bovine beta-lactoglobulin variant L1A/I2S with endogenous ligand (sBlgB#1) Deposited 2016-01-26 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
17–178（162 aa）
|
Mutation：L1A I2S | MYR MYRISTIC ACID × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；1.34 M sodium citrate in 0.1 M Tris pH 7.5
|
Resolution 2.50 Å R-free 0.272 |
| 5HTE Recombinant bovine beta-lactoglobulin variant L1A/I2S (sBlgB#2) Deposited 2016-01-26 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
17–178（162 aa）
|
Mutation：L1A I2S | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；2.3 M (NH4)2SO4 in 0.5 M Tris-HCl pH 8.5
|
Resolution 2.40 Å R-free 0.303 |
| 5IO5 Unliganded form of bovine beta-lactoglobulin, ambient pressure Deposited 2016-03-08 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
17–178（162 aa）
|
Not recorded | CL CHLORIDE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；298 K；1.34 M citric sodium pH 7.5
|
Resolution 2.85 Å R-free 0.295 |
| 5IO7 Bovine beta-lactoglobulin complex with dodecane at high pressure (0.43 GPa) Deposited 2016-03-08 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
17–178（162 aa）
|
Not recorded | D12 DODECANE × 1 CL CHLORIDE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；298 K；1.34 M citric sodium
|
Resolution 2.85 Å R-free 0.229 |
| 5K06 Recombinant bovine beta-lactoglobulin with uncleaved N-terminal methionine (rBlgB) Deposited 2016-05-17 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
17–178（162 aa）
|
Not recorded | GOL GLYCEROL × 2 MYR MYRISTIC ACID × 2 SIN SUCCINIC ACID × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；293 K；3.0 M (NH4)2SO4 solution in 0.2 M Tris-HCl buffer, pH from 7.8 to 8.8
|
Resolution 2.50 Å R-free 0.324 |
| 5LKE Bovine beta-lactoglobulin complex with myristic acid, ambient pressure Deposited 2016-07-22 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
17–178（162 aa）
|
Not recorded | MYR MYRISTIC ACID × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；1.34 M CITRIC SODIUM, 0.1 Tris-HCL, PH 7.5,
|
Resolution 2.80 Å R-free 0.313 |
| 5LKF Bovine beta-lactoglobulin complex with myristic acid at high pressure (0.55 GPa) Deposited 2016-07-22 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
17–178（162 aa）
|
Not recorded | MYR MYRISTIC ACID × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；298 K；1.34 M CITRIC SODIUM, 0.1 M TRIS-HCL,
|
Resolution 2.50 Å R-free 0.398 |
| 5NUJ Engineered beta-lactoglobulin: variant I56F-L39A in complex with chlorpromazine (LG-FA-CLP) Deposited 2017-04-30 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
17–178（162 aa）
|
Mutation：L1A, I2S, I56F, L39A | Z80 3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8；293 K；2.80 M (NH4)2SO4 in 0.1 M Tris-HCl, pH 8.0
|
Resolution 2.60 Å R-free 0.331 |
| 5NUK Engineered beta-lactoglobulin: variant I56F-L39A-M107F in complex with chlorpromazine (LG-FAF-CLP) Deposited 2017-04-30 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
17–178（162 aa）
|
Mutation：L1A, I2S, I56F, L39A, M107F | Z80 3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine × 2 SO4 SULFATE ION × 2 GOL GLYCEROL × 2 PO4 PHOSPHATE ION × 2 CL CHLORIDE ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8；293 K；2.80 M (NH4)2SO4, 0.1 M Tris pH 8.0
|
Resolution 1.70 Å R-free 0.269 |
| 5NUM Engineered beta-lactoglobulin: variant F105L-L39A in complex with chlorpromazine (LG-LA-CLP) Deposited 2017-04-30 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
17–178（162 aa）
|
Mutation：L1A, I2S, L39A, F105L | Z80 3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine × 2 PO4 PHOSPHATE ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8；293 K；2.60 M (NH4)2SO4 in 0.1 M Tris-HCl, pH 8.0
|
Resolution 2.30 Å R-free 0.289 |
| 5NUN Engineered beta-lactoglobulin: variant F105L-L39A-M107F in complex with chlorpromazine (LG-LAF-CLP) Deposited 2017-04-30 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
17–178（162 aa）
|
Mutation：L1A, I2S, L39a, F105L, M107F | Z80 3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8；293 K；2.40 M (NH4)2SO4 in 0.1 M Tris-HCl, pH 8.0
|
Resolution 1.95 Å R-free 0.262 |
| 5Y5C Crystal structure of dha bind to bovine beta-lactoglobulin Deposited 2017-08-08 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
17–178（162 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION；pH 7.5；289 K；1.34M trisodium citrate, 0.1M Tris
|
Resolution 2.61 Å R-free 0.244 |
| 5Y5C Crystal structure of dha bind to bovine beta-lactoglobulin Deposited 2017-08-08 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
17–178（162 aa）
|
Not recorded | HXA DOCOSA-4,7,10,13,16,19-HEXAENOIC ACID × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION；pH 7.5；289 K；1.34M trisodium citrate, 0.1M Tris
|
Resolution 2.61 Å R-free 0.244 |
| 6GE7 Thermodynamic, Crystallographic and Computational Studies of Non Mammalian Fatty Acid Binding to Bovine b-Lactoglobulin Deposited 2018-04-25 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
17–178（162 aa）
|
Not recorded | EW8 nonadecanoic acid × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；293.2 K；protein 20 mg/mL, ligand 10mM, 20mM Tris buffer, pH 8, which were mixed with 4 microliter of well solution. Drops were equilibrated against 1 mL of well solution containing 1.43 M sodium citrate and 0.1M Hepes, pH 7.5
|
Resolution 2.30 Å R-free 0.248 |
| 6GF9 Thermodynamic, Crystallographic and Computational Studies of Non Mammalian Fatty Acid Binding to Bovine b-Lactoglobulin Deposited 2018-04-29 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
17–178（162 aa）
|
Not recorded | X90 heptadecanoic acid × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；293.2 K；protein 20 mg/mL, ligand 10mM, 20mM Tris buffer, pH 8, which were mixed with 4 microliter of well solution. Drops were equilibrated against 1 mL of well solution containing 1.43 M sodium citrate and 0.1M Hepes, pH 7.5
|
Resolution 2.10 Å R-free 0.245 |
| 6GFS Thermodynamic, Crystallographic and Computational Studies of Non Mammalian Fatty Acid Binding to Bovine b-Lactoglobulin Deposited 2018-05-02 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
17–178（162 aa）
|
Not recorded | F15 PENTADECANOIC ACID × 1 CL CHLORIDE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；293.2 K；protein 20 mg/mL, ligand 10mM, 20mM Tris buffer, pH 8, which were mixed with 4 microliter of well solution. Drops were equilibrated against 1 mL of well solution containing 1.43 M sodium citrate and 0.1M Hepes, pH 7.5
|
Resolution 2.00 Å R-free 0.248 |
| 6GHH Thermodynamic, Crystallographic and Computational Studies of Non Mammalian Fatty Acid Binding to Bovine b-Lactoglobulin Deposited 2018-05-07 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
17–178（162 aa）
|
Not recorded | TDA N-TRIDECANOIC ACID × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.3；293.2 K；protein 20 mg/mL, ligand 10mM, 20mM Tris buffer, pH 8, which were mixed with 4 microliter of well solution. Drops were equilibrated against 1 mL of well solution containing 1.43 M sodium citrate and 0.1M Hepes, pH 7.5
|
Resolution 1.90 Å R-free 0.248 |
| 6NKQ The structure of bovine beta-lactoglobulin in novel crystals grown at pH 3.8 Deposited 2019-01-07 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
1–178（178 aa）
|
Not recorded | CA CALCIUM ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 3.8；293 K；Reservoir of 3 M NaCl buffered with sodium citrate at pH 3.8 - heavy white precipitate formed upon mixing of 30 mg/ml protein in water with reservoir solution. Precipitate was removed by centrifugation. The clear remaining 12ul droplet was equilibrated against the reservoir for 12 to 60 hours
|
Resolution 2.30 Å R-free 0.261 |
| 6NKQ The structure of bovine beta-lactoglobulin in novel crystals grown at pH 3.8 Deposited 2019-01-07 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain C
1–178（178 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 3.8；293 K；Reservoir of 3 M NaCl buffered with sodium citrate at pH 3.8 - heavy white precipitate formed upon mixing of 30 mg/ml protein in water with reservoir solution. Precipitate was removed by centrifugation. The clear remaining 12ul droplet was equilibrated against the reservoir for 12 to 60 hours
|
Resolution 2.30 Å R-free 0.261 |
| 6NKQ The structure of bovine beta-lactoglobulin in novel crystals grown at pH 3.8 Deposited 2019-01-07 | Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain D
1–178（178 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 3.8；293 K；Reservoir of 3 M NaCl buffered with sodium citrate at pH 3.8 - heavy white precipitate formed upon mixing of 30 mg/ml protein in water with reservoir solution. Precipitate was removed by centrifugation. The clear remaining 12ul droplet was equilibrated against the reservoir for 12 to 60 hours
|
Resolution 2.30 Å R-free 0.261 |
| 6NKQ The structure of bovine beta-lactoglobulin in novel crystals grown at pH 3.8 Deposited 2019-01-07 | Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain E
1–178（178 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 3.8；293 K；Reservoir of 3 M NaCl buffered with sodium citrate at pH 3.8 - heavy white precipitate formed upon mixing of 30 mg/ml protein in water with reservoir solution. Precipitate was removed by centrifugation. The clear remaining 12ul droplet was equilibrated against the reservoir for 12 to 60 hours
|
Resolution 2.30 Å R-free 0.261 |
| 6NKQ The structure of bovine beta-lactoglobulin in novel crystals grown at pH 3.8 Deposited 2019-01-07 | Assembly 5 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain F
1–178（178 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 3.8；293 K；Reservoir of 3 M NaCl buffered with sodium citrate at pH 3.8 - heavy white precipitate formed upon mixing of 30 mg/ml protein in water with reservoir solution. Precipitate was removed by centrifugation. The clear remaining 12ul droplet was equilibrated against the reservoir for 12 to 60 hours
|
Resolution 2.30 Å R-free 0.261 |
| 6NKQ The structure of bovine beta-lactoglobulin in novel crystals grown at pH 3.8 Deposited 2019-01-07 | Assembly 6 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–178（178 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 3.8；293 K；Reservoir of 3 M NaCl buffered with sodium citrate at pH 3.8 - heavy white precipitate formed upon mixing of 30 mg/ml protein in water with reservoir solution. Precipitate was removed by centrifugation. The clear remaining 12ul droplet was equilibrated against the reservoir for 12 to 60 hours
|
Resolution 2.30 Å R-free 0.261 |
| 6QI6 Trigonal form of WT recombinant bovine beta-lactoglobulin Deposited 2019-01-17 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
17–178（162 aa）
|
Mutation：L1A, I2S | EDO 1,2-ETHANEDIOL × 4 EOH ETHANOL × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8；297 K；2.80 M (NH4)2SO4 in 0.1 M Tris-HCl pH 8.0
|
Resolution 2.00 Å R-free 0.246 |
| 6QI7 Engineered beta-lactoglobulin: variant L39Y in complex with endogenous ligand Deposited 2019-01-17 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
17–178（162 aa）
|
Mutation：L1A, I2S, L39Y | PLM PALMITIC ACID × 2 EDO 1,2-ETHANEDIOL × 6 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；293 K；2.60 M (NH4)2SO4 in 0.1 M Tris-HCl pH 7.1
|
Resolution 2.50 Å R-free 0.262 |
| 6QPD Engineered beta-lactoglobulin: variant I56F Deposited 2019-02-13 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
17–178（162 aa）
|
Mutation：L1A, I2S, I56F | SO4 SULFATE ION × 2 GOL GLYCEROL × 4 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；293 K；2.60 M (NH4)2SO4 in 0.1 M Tris-HCl pH 8.0
|
Resolution 2.00 Å R-free 0.269 |
| 6QPE Engineered beta-lactoglobulin: variant L58F Deposited 2019-02-13 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
17–178（162 aa）
|
Mutation：L1A, I2S, L58F | ACT ACETATE ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；293 K；2.80 M (NH4)2SO4 in 0.1 M Tris-HCl pH 8.0
|
Resolution 2.20 Å R-free 0.251 |
| 6RWP Engineered beta-lactoglobulin: variant L58F in complex with myristic acid Deposited 2019-06-05 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
17–178（162 aa）
|
Mutation：L1A, I2S, L58F | MYR MYRISTIC ACID × 1 SO4 SULFATE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8；293 K；2.80 M (NH4)2SO4 in 0.1 M Tris-HCl pH 8.0, 5 mM myristic acid
|
Resolution 2.10 Å R-free 0.245 |
| 6RWQ Engineered beta-lactoglobulin: variant F105L in complex with myristic acid Deposited 2019-06-05 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
17–178（162 aa）
|
Mutation：L1A, I2S, F105L | MYR MYRISTIC ACID × 2 EDO 1,2-ETHANEDIOL × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；293 K；3.00 M (NH4)2SO4 in 0.1 M Tris-HCl pH 8.0
|
Resolution 2.05 Å R-free 0.255 |
| 6RWR Engineered beta-lactoglobulin: variant M107L in complex with myristic acid Deposited 2019-06-05 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
17–178（162 aa）
|
Mutation：L1A, I2S, M107L | MYR MYRISTIC ACID × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；293 K；1.34 M tri-sodium citrate, 0.1 M Tris pH 8.0
|
Resolution 2.10 Å R-free 0.221 |
| 6RYT Engineered beta-lactoglobulin: variant M107L Deposited 2019-06-11 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
17–178（162 aa）
Chain B
17–178（162 aa）
|
Mutation：L1A, I2S, M107L Mutation：L1A, I2S, M107L | GOL GLYCEROL × 2 PO4 PHOSPHATE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；293 K；2.60 M (NH4)2SO4 in 0.1 Tris-HCl pH 7.9
|
Resolution 2.10 Å R-free 0.278 |
| 6T42 Bovine lactoglobulin complex with decanol Deposited 2019-10-11 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain AAA
17–178（162 aa）
|
Not recorded | DE1 DECAN-1-OL × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；293 K；1.34 M sodium citrate in 0.1 M Tris-HCl pH 7.5, decanol
|
Resolution 1.95 Å R-free 0.229 |
| 6XVE Engineered beta-lactoglobulin: variant F105L Deposited 2020-01-21 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
17–178（162 aa）
|
Mutation：L1A, I2S, F105L | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8；293 K；3.00 M (NH4)2SO4 IN 0.1 M TRIS-HCL PH 8.0
|
Resolution 2.15 Å R-free 0.291 |
| 6ZSQ Crystal structure of the Cisplatin beta-Lactoglobulin adduct formed after 18 h of soaking Deposited 2020-07-16 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain AAA
17–178（162 aa）
|
Not recorded | NH3 AMMONIA × 1 PT PLATINUM (II) ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.9；293 K；Crystals of beta-Lactoglobulin were grown using 3.0 M (NH4)2SO4, 0.1 M sodium/potassium phosphate buffer pH 6.9 as reservoir. Protein crystallizes at a concentration of 18 mg/mL. Crystals of beta-Lactoglobulin were soaked in a solution consisting of 3.0 M (NH4)2SO4, 0.1 M sodium/potassium phosphate buffer (pH 6.9) with 5 mM CDDP (about 1:3 protein to metal ratio).
|
Resolution 2.00 Å R-free 0.224 |
| 6ZSQ Crystal structure of the Cisplatin beta-Lactoglobulin adduct formed after 18 h of soaking Deposited 2020-07-16 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain BBB
17–178（162 aa）
|
Not recorded | PT PLATINUM (II) ION × 2 SO4 SULFATE ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.9；293 K；Crystals of beta-Lactoglobulin were grown using 3.0 M (NH4)2SO4, 0.1 M sodium/potassium phosphate buffer pH 6.9 as reservoir. Protein crystallizes at a concentration of 18 mg/mL. Crystals of beta-Lactoglobulin were soaked in a solution consisting of 3.0 M (NH4)2SO4, 0.1 M sodium/potassium phosphate buffer (pH 6.9) with 5 mM CDDP (about 1:3 protein to metal ratio).
|
Resolution 2.00 Å R-free 0.224 |
| 6ZSR Crystal structure of the Cisplatin beta-Lactoglobulin adduct formed after 72 h of soaking Deposited 2020-07-16 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain AAA
17–178（162 aa）
|
Not recorded | NH3 AMMONIA × 1 PT PLATINUM (II) ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.9；293 K；Crystals of beta-Lactoglobulin were grown using 3.0 M (NH4)2SO4, 0.1 M sodium/potassium phosphate buffer pH 6.9 as reservoir. Protein crystallizes at a concentration of 18 mg/mL. Crystals of beta-Lactoglobulin were soaked in a solution consisting of 3.0 M (NH4)2SO4, 0.1 M sodium/potassium phosphate buffer (pH 6.9) with 5 mM CDDP (about 1:3 protein to metal ratio).
|
Resolution 2.00 Å R-free 0.283 |
| 6ZSR Crystal structure of the Cisplatin beta-Lactoglobulin adduct formed after 72 h of soaking Deposited 2020-07-16 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain BBB
17–178（162 aa）
|
Not recorded | NH3 AMMONIA × 1 PT PLATINUM (II) ION × 3 SO4 SULFATE ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.9；293 K；Crystals of beta-Lactoglobulin were grown using 3.0 M (NH4)2SO4, 0.1 M sodium/potassium phosphate buffer pH 6.9 as reservoir. Protein crystallizes at a concentration of 18 mg/mL. Crystals of beta-Lactoglobulin were soaked in a solution consisting of 3.0 M (NH4)2SO4, 0.1 M sodium/potassium phosphate buffer (pH 6.9) with 5 mM CDDP (about 1:3 protein to metal ratio).
|
Resolution 2.00 Å R-free 0.283 |
| 7BF7 Mutant L58F of recombinant bovine beta-lactoglobulin in complex with tetracaine Deposited 2021-01-01 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain AAA
17–178（162 aa）
|
Mutation：L1A, I2S, L58F | TE4 Tetracaine × 2 SO4 SULFATE ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8；293 K；2.8 M ammonium sulfate in 0.5 M Tris-HCl pH 8.0
|
Resolution 2.10 Å R-free 0.249 |
| 7BF8 Mutant I56F of recombinant bovine beta-lactoglobulin in complex with tetracaine Deposited 2021-01-01 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain AAA
17–178（162 aa）
Chain BBB
17–178（162 aa）
|
Mutation：L1A, I2S, I56F Mutation：L1A, I2S, I56F | SO4 SULFATE ION × 3 TE4 Tetracaine × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8；293 K；2.4 M ammonium sulfate in 0.5 M Tris-HCl pH 8.0
|
Resolution 1.80 Å R-free 0.222 |
| 7BF9 Mutant M107L of recombinant bovine beta-lactoglobulin in complex with tetracaine Deposited 2021-01-01 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain AAA
17–178（162 aa）
|
Mutation：L1A, I2S, M107L | TE4 Tetracaine × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8；293 K；1,34 M tri-sodium citrate in 0.5 Tris o pH 8.0
|
Resolution 1.80 Å R-free 0.223 |
| 7BGA Mutant F105A of recombinant beta-lactoglobulin in complex with endogenous ligand Deposited 2021-01-06 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain AAA
17–178（162 aa）
|
Mutation：L1A, I2S, F105A | DAO LAURIC ACID × 2 SO4 SULFATE ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；293 K；2.6 M ammonium sulfate in 0.5 M Tris-HCl pH 8.5
|
Resolution 1.90 Å R-free 0.243 |
| 7BGX Mutant F105L of recombinant beta-lactoglobulin Deposited 2021-01-08 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain AAA
17–178（162 aa）
|
Mutation：L1A, I2S, F105L | GOL GLYCEROL × 4 SO4 SULFATE ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8；293 K；2.4 M ammonium sulfate in 0.5 M Tris-HCl pH 8.0
|
Resolution 2.00 Å R-free 0.246 |
| 7BGZ Mutant L39K of recombinant beta-lactoglobulin in complex with endogenous ligand Deposited 2021-01-09 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain AAA
17–178（162 aa）
|
Mutation：L1A, I2S, L39K | DKA DECANOIC ACID × 2 EDO 1,2-ETHANEDIOL × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；293 K；3.0 M ammonium sulfate in 0.5 M Tris-HCl pH 8.5
|
Resolution 2.40 Å R-free 0.266 |
| 7BH0 Mutant L39Y of recombinant beta-lactoglobulin in complex with endogenous ligand Deposited 2021-01-09 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain AAA
17–178（162 aa）
|
Mutation：L1A, I2S, L39Y | DAO LAURIC ACID × 2 CL CHLORIDE ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.1；293 K；2.2 M ammonium sulfate in 0.5 M Tris-HCl pH 7.1
|
Resolution 2.10 Å R-free 0.275 |
| 7KOT Energetic and structural effects of the Tanford transition on the ligand recognition of bovine Beta-lactoglobulin Deposited 2020-11-09 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
17–178（162 aa）
|
Not recorded | SDS DODECYL SULFATE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8；277.15 K；0.1 M NaCl, pH 4.5 and in 0.05 M Tris-HCl, 0.1 M NaCl, pH 8.0
|
Resolution 1.74 Å R-free 0.229 |
| 7KP5 Energetic and structural effects of the Tanford transition on the ligand recognition of bovine Beta-lactoglobulin Deposited 2020-11-10 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain AA1
17–178（162 aa）
Chain BA1
17–178（162 aa）
|
Not recorded | SDS DODECYL SULFATE × 3 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.5；277.15 K；12-15 mg/mL protein in 0.05M acetate and 0.1 M NaCl. Combined 1:1 with 0.05M KH2PO4, 20% PEG
|
Resolution 2.40 Å R-free 0.269 |
| 7NQB X.ray structure of the oxaliplatin/beta-lactoglobulin adduct Deposited 2021-03-01 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain AAA
17–178（162 aa）
|
Not recorded | PT PLATINUM (II) ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；293 K；0.2M KCl, 0.04M HEPES, 35% v/v pentaerythritol propoxylate
|
Resolution 2.01 Å R-free 0.284 |
| 7NQB X.ray structure of the oxaliplatin/beta-lactoglobulin adduct Deposited 2021-03-01 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain BBB
17–178（162 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；293 K；0.2M KCl, 0.04M HEPES, 35% v/v pentaerythritol propoxylate
|
Resolution 2.01 Å R-free 0.284 |
| 7Q17 Beta-lactoglobulin mutant FAW (I56F/L39A/M107W), unliganded form Deposited 2021-10-18 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain AAA
17–178（162 aa）
|
Mutation：L1A, I2S, L39A, I56F, M107W | EDO 1,2-ETHANEDIOL × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；293 K；2.40 M ammonium sulfate, 0.5 M Tris-HCl pH 8.5
|
Resolution 1.80 Å R-free 0.226 |
| 7Q18 Beta-lactoglobulin mutant FAF (I56F/L39A/M107F), unliganded form Deposited 2021-10-18 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain AAA
17–178（162 aa）
Chain BBB
17–178（162 aa）
|
Mutation：L1A, I2S, L39A, I56F, M107F Mutation：L1A, I2S, L39A, I56F, M107F | SO4 SULFATE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；293 K；2.40 M (NH4)2SO4, 0.5 M Tris-HCl pH 8.5
|
Resolution 1.80 Å R-free 0.233 |
| 7Q19 Beta-lactoglobulin mutant FAW (I56F/L39A/M107W) in complex with desipramine (FAW-DSM#3) Deposited 2021-10-18 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain AAA
17–178（162 aa）
|
Mutation：L1A, I2S, L39A, I56F, M107W | DSM 3-(10,11-DIHYDRO-5H-DIBENZO[B,F]AZEPIN-5-YL)-N-METHYLPROPAN-1-AMINE × 2 EDO 1,2-ETHANEDIOL × 2 SO4 SULFATE ION × 4 CL CHLORIDE ION × 6 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；293 K；2.40 M (NH4)2SO4, 0.5 M Tris-HCl pH 8.5, desipramine
|
Resolution 1.55 Å R-free 0.234 |
| 7Q2N Beta-lactoglobulin mutant FAF (I56F/L39A/M107F) in complex with desipramine (FAF-DSM) Deposited 2021-10-25 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain AAA
17–178（162 aa）
Chain BBB
17–178（162 aa）
|
Mutation：L1A, I2S, L39A, I56F, M107F Mutation：L1A, I2S, L39A, I56F, M107F | DSM 3-(10,11-DIHYDRO-5H-DIBENZO[B,F]AZEPIN-5-YL)-N-METHYLPROPAN-1-AMINE × 4 GOL GLYCEROL × 1 CL CHLORIDE ION × 1 EDO 1,2-ETHANEDIOL × 1 SO4 SULFATE ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；293 K；2.40 M (NH4)2SO4, 0.5 M Tris-HCl pH 8.5, desipramine
|
Resolution 1.70 Å R-free 0.233 |
| 7Q2O Beta-lactoglobulin mutant FAW (I56F/L39A/M107W) in complex with desipramine (FAW-DSM#1) Deposited 2021-10-25 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain AAA
17–178（162 aa）
Chain BBB
17–178（162 aa）
|
Mutation：L1A, I2S, L39A, I56F, M107W Mutation：L1A, I2S, L39A, I56F, M107W | SO4 SULFATE ION × 1 DSM 3-(10,11-DIHYDRO-5H-DIBENZO[B,F]AZEPIN-5-YL)-N-METHYLPROPAN-1-AMINE × 4 CL CHLORIDE ION × 1 EDO 1,2-ETHANEDIOL × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；293 K；2.20 M (NH4)2SO4, 0.5 M Tris-HCl pH 8.5
|
Resolution 1.80 Å R-free 0.221 |
| 7Q2P Beta-lactoglobulin mutant FAW (I56F/L39A/M107W) in complex with desipramine (FAW-DSM#2) Deposited 2021-10-25 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain AAA
17–178（162 aa）
Chain BBB
17–178（162 aa）
|
Mutation：L1A, I2S, L39A, I56F, M107W Mutation：L1A, I2S, L39A, I56F, M107W | EDO 1,2-ETHANEDIOL × 2 DSM 3-(10,11-DIHYDRO-5H-DIBENZO[B,F]AZEPIN-5-YL)-N-METHYLPROPAN-1-AMINE × 3 SO4 SULFATE ION × 2 CL CHLORIDE ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；293 K；2.40 M (NH4)2SO4, 0.5 M Tris-HCl pH 8.5
|
Resolution 1.69 Å R-free 0.235 |
| 7WQL Bovin Beta-lactoglobulin binding with zinc ions Deposited 2022-01-25 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
17–178（162 aa）
Chain B
17–178（162 aa）
|
Not recorded | ZN ZINC ION × 6 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；293.15 K；20% PEG3350, 200 mM Ammonium formate
|
Resolution 2.00 Å R-free 0.261 |
| 7Z9Z Mutant L39Y of recombinant bovine beta-lactoglobulin in complex with pramocaine Deposited 2022-03-21 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain AAA
19–178（160 aa）
|
Mutation：L1A, I2S, L39Y | PX9 Pramocaine × 2 SO4 SULFATE ION × 2 CL CHLORIDE ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；293 K；2.4 M ammonium sulfate in 0.5 M Tris-HCl, pH 8.5
|
Resolution 2.50 Å R-free 0.276 |
| 7ZA0 Mutant L58F of recombinant bovine beta-lactoglobulin in complex with pramocaine Deposited 2022-03-21 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain AAA
17–178（162 aa）
|
Mutation：L1A, I2S, L58F | PX9 Pramocaine × 2 SO4 SULFATE ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；293 K；2.2 M ammonium sulfate in 0.5 M Tris-HCl pH 8.5
|
Resolution 2.10 Å R-free 0.224 |
| 7ZCD Mutant L39Y-L58F of recombinant bovine beta-lactoglobulin in complex with pramocaine Deposited 2022-03-27 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain AAA
19–178（160 aa）
|
Mutation：L1A, I2S, L39Y, L58F | PX9 Pramocaine × 2 SO4 SULFATE ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；293 K；2.2M ammonium sulfate, 0.5 M Tris-HCl, pH 8.5
|
Resolution 2.10 Å R-free 0.269 |
| 7ZLF Mutant L39Y-L58F of recombinant bovine beta-lactoglobulin in complex with endogenous fatty acid Deposited 2022-04-14 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain AAA
19–178（160 aa）
|
Mutation：L1A, I2S, L39Y, L58F | DAO LAURIC ACID × 2 EDO 1,2-ETHANEDIOL × 4 SO4 SULFATE ION × 2 CL CHLORIDE ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；293 K；2.4 M in 0.5 M Tris-HCl, pH 8.5
|
Resolution 2.10 Å R-free 0.237 |
| 9I7N Beta-lactoglobulin complex with retinol post lyophilization Deposited 2025-01-31 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–178（178 aa）
|
Not recorded | RTL RETINOL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7.4；293 K；2.4 M ammonium sulfate
0.5 M TRIS
|
Resolution 1.95 Å R-free 0.211 |
| 9I7O Beta-lactoglobulin complex with retinol Deposited 2025-01-31 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–178（178 aa）
|
Not recorded | RTL RETINOL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7.4；293 K；2.4 M ammonium sulfate
0.5 M TRIS
|
Resolution 2.00 Å R-free 0.197 |
| 9IAH Structure of beta-lactoglobulin fibril Deposited 2025-02-10 | Assembly 1 Protein homooligomer Homooligomer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count |
Chain A
17–50（34 aa）
Chain B
17–50（34 aa）
Chain C
17–50（34 aa）
Chain D
17–50（34 aa）
Chain E
17–50（34 aa）
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 2.5
cryo-EM vitrification conditions
Cryogen ETHANE-PROPANE；3.7 ul sample was applied and blotted for 6 s after a wait time of 30 s with a force of 0
|
Resolution 3.17 Å |
| 9JHF Cryo-EM structure of beta-LG fibril Deposited 2024-09-09 | Assembly 1 Protein homooligomer Homooligomer；Protein × 6 PDB declaration: hexameric（6） Consistent with protein count |
Chain AA
17–48（32 aa）
Chain AB
17–48（32 aa）
Chain AC
17–48（32 aa）
Chain AD
17–48（32 aa）
Chain AE
17–48（32 aa）
Chain AF
17–48（32 aa）
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 2
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 4.06 Å |
| 9JHG Cryo-em structure of beta-LG fibril Deposited 2024-09-09 | Assembly 1 Protein homooligomer Homooligomer；Protein × 6 PDB declaration: hexameric（6） Consistent with protein count |
Chain A
17–48（32 aa）
Chain B
17–48（32 aa）
Chain C
17–48（32 aa）
Chain D
17–48（32 aa）
Chain E
17–48（32 aa）
Chain F
17–48（32 aa）
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 2
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.38 Å |
| 9JHH Cryo-em structure of beta-LG fibril Deposited 2024-09-09 | Assembly 1 Protein homooligomer Homooligomer；Protein × 6 PDB declaration: hexameric（6） Consistent with protein count |
Chain A
17–48（32 aa）
Chain B
17–48（32 aa）
Chain C
17–48（32 aa）
Chain D
17–48（32 aa）
Chain E
17–48（32 aa）
Chain F
17–48（32 aa）
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 2
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.45 Å |
| 9JHI Cryo-em structure of beta-LG fibril Deposited 2024-09-09 | Assembly 1 Protein homooligomer Homooligomer；Protein × 6 PDB declaration: hexameric（6） Consistent with protein count |
Chain AA
17–48（32 aa）
Chain AB
17–48（32 aa）
Chain AC
17–48（32 aa）
Chain AD
17–48（32 aa）
Chain AE
17–48（32 aa）
Chain AF
17–48（32 aa）
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 2
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.73 Å |