当前蛋白身份：P08525
重新检索
差异标签只比较当前检索结果；所有PDB和assembly原始记录仍分别保留。
相关结构差异明细
一行代表一个 PDB 条目中的一个 biological assembly；同一蛋白的多个单体会分别列出。
| PDB 条目 | Assembly / 聚集状态 | 构建体 | 突变与修饰 | 配体、离子与非聚合物 | 实验方法 | 实验环境 | 结构质量 |
|---|---|---|---|---|---|---|---|
| 1KB9 YEAST CYTOCHROME BC1 COMPLEX 提交 2001-11-05 | Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 11 PDB 声明：undecameric（11） 与蛋白数一致 |
链 H
2–94（93 aa）
片段：RESIDUES 2-94
|
未记录 | PCF 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE × 1 UMQ UNDECYL-MALTOSIDE × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 3 SMA STIGMATELLIN A × 1 UQ6 5-(3,7,11,15,19,23-HEXAMETHYL-TETRACOSA-2,6,10,14,18,22-HEXAENYL)-2,3-DIMETHOXY-6-METHYL-BENZENE-1,4-DIOL × 1 PIE 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoinositol × 1 PEF DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE × 2 CDL CARDIOLIPIN × 1 FES FE2/S2 (INORGANIC) CLUSTER × 1 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION, SITTING DROP；pH 8；PEG4000, pH 8, VAPOR DIFFUSION, SITTING DROP
|
分辨率 2.30 Å R-free 0.249 |
| 1KYO YEAST CYTOCHROME BC1 COMPLEX WITH BOUND SUBSTRATE CYTOCHROME C 提交 2002-02-05 | Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 23 PDB 声明：23-meric（23） 与蛋白数一致 |
链 H
2–94（93 aa）
片段：RESIDUES 2-94
链 S
2–94（93 aa）
片段：RESIDUES 2-94
|
未记录 | HEC HEME C × 7 SMA STIGMATELLIN A × 2 FES FE2/S2 (INORGANIC) CLUSTER × 2 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION, HANGING DROP；pH 7.5；277 K；PEG4000, 20 mM Tris, 0.05 % Undecyl-maltopyranoside, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 277K
|
分辨率 2.97 Å R-free 0.268 |
| 1P84 HDBT inhibited Yeast Cytochrome bc1 Complex 提交 2003-05-06 | Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 18 PDB 声明：octadecameric（18） 与蛋白数一致 |
链 H
2–94（93 aa）
|
未记录 | 3PH 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE × 4 UMQ UNDECYL-MALTOSIDE × 2 HEC HEME C × 6 DBT 5-HEPTYL-6-HYDROXY-1,3-BENZOTHIAZOLE-4,7-DIONE × 2 UQ6 5-(3,7,11,15,19,23-HEXAMETHYL-TETRACOSA-2,6,10,14,18,22-HEXAENYL)-2,3-DIMETHOXY-6-METHYL-BENZENE-1,4-DIOL × 2 3PE 1,2-Distearoyl-sn-glycerophosphoethanolamine × 4 PC1 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE × 2 CDL CARDIOLIPIN × 2 FES FE2/S2 (INORGANIC) CLUSTER × 2 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION, SITTING DROP；pH 7.5；277 K；PEG4000, pH 7.5, VAPOR DIFFUSION, SITTING DROP, temperature 277K
|
分辨率 2.50 Å R-free 0.252 |
| 2IBZ Yeast Cytochrome BC1 Complex with Stigmatellin 提交 2006-09-12 | Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 11 PDB 声明：undecameric（11） 与蛋白数一致 |
链 G
1–94（94 aa）
|
未记录 | HEC HEME C × 3 UQ6 5-(3,7,11,15,19,23-HEXAMETHYL-TETRACOSA-2,6,10,14,18,22-HEXAENYL)-2,3-DIMETHOXY-6-METHYL-BENZENE-1,4-DIOL × 1 SMA STIGMATELLIN A × 1 FES FE2/S2 (INORGANIC) CLUSTER × 1 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION, SITTING DROP；pH 8；277 K；precipitant PEG4000, pH 8.0, VAPOR DIFFUSION, SITTING DROP, temperature 277K
|
分辨率 2.30 Å R-free 0.256 |
| 3CX5 Structure of complex III with bound cytochrome c in reduced state and definition of a minimal core interface for electron transfer. 提交 2008-04-23 | Assembly 1 其他组合 异源复合物；蛋白 × 23 PDB 声明：23-meric（23） 与蛋白数一致 |
链 H
2–94（93 aa）
链 S
2–94（93 aa）
|
未记录 | 6PH (1R)-2-(phosphonooxy)-1-[(tridecanoyloxy)methyl]ethyl pentadecanoate × 2 UMQ UNDECYL-MALTOSIDE × 2 HEM PROTOPORPHYRIN IX CONTAINING FE × 7 SMA STIGMATELLIN A × 2 8PE (2R)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(tetradecanoyloxy)propyl octadecanoate × 2 9PE (1R)-2-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-1-[(heptanoyloxy)methyl]ethyl octadecanoate × 2 CN5 (5S,11R)-5,8,11-trihydroxy-5,11-dioxido-17-oxo-4,6,10,12,16-pentaoxa-5,11-diphosphaoctadec-1-yl pentadecanoate × 1 7PH (1R)-2-(dodecanoyloxy)-1-[(phosphonooxy)methyl]ethyl tetradecanoate × 2 CN3 (2R,5S,11R,14R)-5,8,11-trihydroxy-2-(nonanoyloxy)-5,11-dioxido-16-oxo-14-[(propanoyloxy)methyl]-4,6,10,12,15-pentaoxa-5,11-diphosphanonadec-1-yl undecanoate × 2 FES FE2/S2 (INORGANIC) CLUSTER × 2 | X-RAY DIFFRACTION |
X-ray结晶条件
Microbatch (paraffin oil)；pH 7.5；277 K；1M Sucrose, 10% DMSO, 20mM Tris pH 7.5, 80mM NaCl, 0.05 % UM, 1 M stigmatellin, 5% PEG 4000, Microbatch (paraffin oil), temperature 277K
|
分辨率 1.90 Å R-free 0.263 |
| 3CXH Structure of yeast complex III with isoform-2 cytochrome c bound and definition of a minimal core interface for electron transfer. 提交 2008-04-24 | Assembly 1 其他组合 异源复合物；蛋白 × 23 PDB 声明：23-meric（23） 与蛋白数一致 |
链 H
2–94（93 aa）
链 S
2–94（93 aa）
|
未记录 | UMQ UNDECYL-MALTOSIDE × 2 HEM PROTOPORPHYRIN IX CONTAINING FE × 7 SMA STIGMATELLIN A × 2 8PE (2R)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(tetradecanoyloxy)propyl octadecanoate × 2 CN6 (2R,5R,11S,14R)-2-(butanoyloxy)-5,8,11-trihydroxy-5,11-dioxido-16-oxo-14-[(propanoyloxy)methyl]-4,6,10,12,15-pentaoxa-5,11-diphosphanonadec-1-yl undecanoate × 2 9PE (1R)-2-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-1-[(heptanoyloxy)methyl]ethyl octadecanoate × 2 7PH (1R)-2-(dodecanoyloxy)-1-[(phosphonooxy)methyl]ethyl tetradecanoate × 2 FES FE2/S2 (INORGANIC) CLUSTER × 2 6PH (1R)-2-(phosphonooxy)-1-[(tridecanoyloxy)methyl]ethyl pentadecanoate × 2 | X-RAY DIFFRACTION |
X-ray结晶条件
Microbatch (Paraffin oil)；pH 7.5；277 K；1M Sucrose, 10% DMSO, 20mM Tris pH 7.5, 80mM NaCl, 0.05 % UM, 1 M stigmatellin, 5% PEG 4000, Microbatch (Paraffin oil), temperature 277K
|
分辨率 2.50 Å R-free 0.256 |
| 4PD4 Structural analysis of atovaquone-inhibited cytochrome bc1 complex reveals the molecular basis of antimalarial drug action 提交 2014-04-17 | Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 22 PDB 声明：22-meric（22） 与蛋白数一致 |
链 H
2–94（93 aa）
|
未记录 | UMQ UNDECYL-MALTOSIDE × 2 3PH 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE × 6 HEM PROTOPORPHYRIN IX CONTAINING FE × 6 AOQ 2-[trans-4-(4-chlorophenyl)cyclohexyl]-3-hydroxynaphthalene-1,4-dione × 2 3PE 1,2-Distearoyl-sn-glycerophosphoethanolamine × 2 UQ6 5-(3,7,11,15,19,23-HEXAMETHYL-TETRACOSA-2,6,10,14,18,22-HEXAENYL)-2,3-DIMETHOXY-6-METHYL-BENZENE-1,4-DIOL × 2 FES FE2/S2 (INORGANIC) CLUSTER × 2 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION, HANGING DROP；pH 6.8；277.2 K；polyethylene glycol 4000, DMSO, Sucrose, Potassium phosphate, n-undecyl-?-D-maltopyranoside, atovaquone
|
分辨率 3.04 Å R-free 0.297 |
| 6HU9 III2-IV2 mitochondrial respiratory supercomplex from S. cerevisiae 提交 2018-10-05 | Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 44 PDB 声明：44-meric（44） 与蛋白数一致 |
链 H
2–94（93 aa）
链 S
2–94（93 aa）
|
未记录 | PEF DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE × 28 HEM PROTOPORPHYRIN IX CONTAINING FE × 4 UQ6 5-(3,7,11,15,19,23-HEXAMETHYL-TETRACOSA-2,6,10,14,18,22-HEXAENYL)-2,3-DIMETHOXY-6-METHYL-BENZENE-1,4-DIOL × 1 CDL CARDIOLIPIN × 8 PCF 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE × 8 HEC HEME C × 2 FES FE2/S2 (INORGANIC) CLUSTER × 2 CU COPPER (II) ION × 2 HEA HEME-A × 4 CA CALCIUM ION × 2 MG MAGNESIUM ION × 2 CUA DINUCLEAR COPPER ION × 4 ZN ZINC ION × 2 | ELECTRON MICROSCOPY |
cryo-EM缓冲液
pH 7.2
cryo-EM玻璃化条件
冷冻剂 ETHANE；3 microL of sample applied to negatively glow discharged grid, blot force -10; blotting time 8.5 sec
|
分辨率 3.35 Å |
| 6T0B The III2-IV(5B)2 respiratory supercomplex from S. cerevisiae 提交 2019-10-02 | Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 46 PDB 声明：46-meric（46） 与蛋白数一致 |
链 H
1–94（94 aa）
链 S
1–94（94 aa）
|
未记录 | CDL CARDIOLIPIN × 8 PEF DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE × 26 HEM PROTOPORPHYRIN IX CONTAINING FE × 4 PCF 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE × 7 HEC HEME C × 2 FES FE2/S2 (INORGANIC) CLUSTER × 2 CU COPPER (II) ION × 2 HEA HEME-A × 4 CA CALCIUM ION × 2 MG MAGNESIUM ION × 2 CUA DINUCLEAR COPPER ION × 2 ZN ZINC ION × 2 | ELECTRON MICROSCOPY |
cryo-EM缓冲液
pH 7.2
cryo-EM玻璃化条件
冷冻剂 ETHANE；3 microliter of sample applied to negatively glow discharged grid, blot force -10; blotting time 8.5 s
|
分辨率 2.80 Å |
| 6T15 The III2-IV(5B)1 respiratory supercomplex from S. cerevisiae 提交 2019-10-03 | Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 33 PDB 声明：33-meric（33） 与蛋白数一致 |
链 H
1–94（94 aa）
链 S
1–94（94 aa）
|
未记录 | PEF DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE × 18 HEM PROTOPORPHYRIN IX CONTAINING FE × 4 CDL CARDIOLIPIN × 7 PCF 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE × 6 HEC HEME C × 2 FES FE2/S2 (INORGANIC) CLUSTER × 2 CU COPPER (II) ION × 1 HEA HEME-A × 2 MG MAGNESIUM ION × 1 CUA DINUCLEAR COPPER ION × 1 ZN ZINC ION × 1 | ELECTRON MICROSCOPY |
cryo-EM缓冲液
pH 7.2
cryo-EM玻璃化条件
冷冻剂 ETHANE；3 microliter of sample applied to negatively glow discharged grid, blot force -10; blotting time 8.5 s
|
分辨率 3.29 Å |
| 6YMX CIII2/CIV respiratory supercomplex from Saccharomyces cerevisiae 提交 2020-04-10 | Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 32 PDB 声明：32-meric（32） 与蛋白数一致 |
链 H
2–94（93 aa）
链 S
2–94（93 aa）
|
未记录 | CU COPPER (II) ION × 1 HEA HEME-A × 2 PTY PHOSPHATIDYLETHANOLAMINE × 7 CN3 (2R,5S,11R,14R)-5,8,11-trihydroxy-2-(nonanoyloxy)-5,11-dioxido-16-oxo-14-[(propanoyloxy)methyl]-4,6,10,12,15-pentaoxa-5,11-diphosphanonadec-1-yl undecanoate × 2 CUA DINUCLEAR COPPER ION × 1 PCF 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE × 5 ZN ZINC ION × 1 6PH (1R)-2-(phosphonooxy)-1-[(tridecanoyloxy)methyl]ethyl pentadecanoate × 2 HEM PROTOPORPHYRIN IX CONTAINING FE × 6 8PE (2R)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(tetradecanoyloxy)propyl octadecanoate × 2 CN5 (5S,11R)-5,8,11-trihydroxy-5,11-dioxido-17-oxo-4,6,10,12,16-pentaoxa-5,11-diphosphaoctadec-1-yl pentadecanoate × 1 UQ6 5-(3,7,11,15,19,23-HEXAMETHYL-TETRACOSA-2,6,10,14,18,22-HEXAENYL)-2,3-DIMETHOXY-6-METHYL-BENZENE-1,4-DIOL × 2 9PE (1R)-2-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-1-[(heptanoyloxy)methyl]ethyl octadecanoate × 2 7PH (1R)-2-(dodecanoyloxy)-1-[(phosphonooxy)methyl]ethyl tetradecanoate × 2 FES FE2/S2 (INORGANIC) CLUSTER × 2 | ELECTRON MICROSCOPY |
cryo-EM缓冲液
pH 7.4
cryo-EM玻璃化条件
冷冻剂 ETHANE
|
分辨率 3.17 Å |
| 8E7S III2IV2 respiratory supercomplex from Saccharomyces cerevisiae with 4 bound UQ6 提交 2022-08-24 | Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 44 PDB 声明：44-meric（44） 与蛋白数一致 |
链 H
1–94（94 aa）
链 h
1–94（94 aa）
|
未记录 | PEF DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE × 24 FES FE2/S2 (INORGANIC) CLUSTER × 2 CDL CARDIOLIPIN × 10 PCF 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE × 6 CN5 (5S,11R)-5,8,11-trihydroxy-5,11-dioxido-17-oxo-4,6,10,12,16-pentaoxa-5,11-diphosphaoctadec-1-yl pentadecanoate × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 6 UQ6 5-(3,7,11,15,19,23-HEXAMETHYL-TETRACOSA-2,6,10,14,18,22-HEXAENYL)-2,3-DIMETHOXY-6-METHYL-BENZENE-1,4-DIOL × 4 HEA HEME-A × 4 CU COPPER (II) ION × 2 CUA DINUCLEAR COPPER ION × 4 | ELECTRON MICROSCOPY |
cryo-EM缓冲液
pH 7.2
cryo-EM玻璃化条件
冷冻剂 ETHANE
|
分辨率 3.20 Å |
| 8EC0 III2IV respiratory supercomplex from Saccharomyces cerevisiae cardiolipin-lacking mutant 提交 2022-08-31 | Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 30 PDB 声明：30-meric（30） 与蛋白数一致 |
链 H
1–94（94 aa）
链 h
1–94（94 aa）
|
未记录 | PEF DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE × 15 PGT (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE × 7 FES FE2/S2 (INORGANIC) CLUSTER × 2 PCF 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE × 4 HEM PROTOPORPHYRIN IX CONTAINING FE × 6 UQ6 5-(3,7,11,15,19,23-HEXAMETHYL-TETRACOSA-2,6,10,14,18,22-HEXAENYL)-2,3-DIMETHOXY-6-METHYL-BENZENE-1,4-DIOL × 2 CU COPPER (II) ION × 1 HEA HEME-A × 2 CUA DINUCLEAR COPPER ION × 2 | ELECTRON MICROSCOPY |
cryo-EM缓冲液
pH 7.2
cryo-EM玻璃化条件
冷冻剂 ETHANE
|
分辨率 3.30 Å |
| 9BPB Tethered respiratory III2IV2 supercomplex from Saccharomyces cerevisiae 提交 2024-05-07 | Assembly 1 信息不足 异源复合物；蛋白 × 42 PDB 声明：42-meric（42） 与蛋白数一致 |
链 H
1–94（94 aa）
链 R
1–94（94 aa）
|
未记录 | CDL CARDIOLIPIN × 8 6PH (1R)-2-(phosphonooxy)-1-[(tridecanoyloxy)methyl]ethyl pentadecanoate × 2 8PE (2R)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(tetradecanoyloxy)propyl octadecanoate × 2 CN5 (5S,11R)-5,8,11-trihydroxy-5,11-dioxido-17-oxo-4,6,10,12,16-pentaoxa-5,11-diphosphaoctadec-1-yl pentadecanoate × 1 UQ6 5-(3,7,11,15,19,23-HEXAMETHYL-TETRACOSA-2,6,10,14,18,22-HEXAENYL)-2,3-DIMETHOXY-6-METHYL-BENZENE-1,4-DIOL × 4 HEM PROTOPORPHYRIN IX CONTAINING FE × 4 9PE (1R)-2-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-1-[(heptanoyloxy)methyl]ethyl octadecanoate × 2 PEF DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE × 6 HEC HEME C × 2 FES FE2/S2 (INORGANIC) CLUSTER × 2 PCF 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE × 8 PTY PHOSPHATIDYLETHANOLAMINE × 10 HEA HEME-A × 4 CU COPPER (II) ION × 2 CA CALCIUM ION × 2 CN3 (2R,5S,11R,14R)-5,8,11-trihydroxy-2-(nonanoyloxy)-5,11-dioxido-16-oxo-14-[(propanoyloxy)methyl]-4,6,10,12,15-pentaoxa-5,11-diphosphanonadec-1-yl undecanoate × 2 MG MAGNESIUM ION × 2 CUA DINUCLEAR COPPER ION × 2 ZN ZINC ION × 2 | ELECTRON MICROSCOPY |
cryo-EM缓冲液
pH 7.5
cryo-EM玻璃化条件
冷冻剂 ETHANE；3 uL of sample, 5 s blot time, 30 s hold time, 0 blot force.
|
分辨率 2.57 Å |
| 9ETZ III2IV respiratory supercomplex from Saccharomyces cerevisiae 提交 2024-03-27 | Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 32 PDB 声明：32-meric（32） 与蛋白数一致 |
链 H
2–94（93 aa）
链 S
2–94（93 aa）
|
未记录 | CDL CARDIOLIPIN × 11 HEM PROTOPORPHYRIN IX CONTAINING FE × 4 PEF DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE × 26 PCF 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE × 6 UQ6 5-(3,7,11,15,19,23-HEXAMETHYL-TETRACOSA-2,6,10,14,18,22-HEXAENYL)-2,3-DIMETHOXY-6-METHYL-BENZENE-1,4-DIOL × 2 HEC HEME C × 2 FES FE2/S2 (INORGANIC) CLUSTER × 2 CU COPPER (II) ION × 1 HEA HEME-A × 2 CA CALCIUM ION × 1 MG MAGNESIUM ION × 1 CUA DINUCLEAR COPPER ION × 1 ZN ZINC ION × 1 | ELECTRON MICROSCOPY |
cryo-EM缓冲液
pH 7.4
cryo-EM玻璃化条件
冷冻剂 ETHANE
|
分辨率 2.40 Å |