Current Protein Identity:P55081
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 5F5S Crystal structure of the Prp38-MFAP1 complex of Homo sapiens Deposited 2015-12-04 | Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain B
267–344(78 aa)
Fragment:UNP residues 267-344
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION;pH 4.4;277.15 K;0.1 M sodium acetate, pH 4.4 and 15% (v/v) 1,3-Butandiol
|
Resolution 2.40 Å R-free 0.261 |
| 5O9Z Cryo-EM structure of a pre-catalytic human spliceosome primed for activation (B complex) Deposited 2017-06-20 | Assembly 1 Protein–RNA Heteromer;Protein × 52 PDB declaration: 57-meric(57) Consistent with all polymers |
Chain K
1–439(439 aa)
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.9
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 4.50 Å |
| 6AHD The Cryo-EM Structure of Human Pre-catalytic Spliceosome (B complex) at 3.8 angstrom resolution Deposited 2018-08-17 | Assembly 1 Protein–RNA Heteromer;Protein × 58 PDB declaration: 63-meric(63) Consistent with all polymers |
Chain 0
1–439(439 aa)
|
Not recorded | IHP INOSITOL HEXAKISPHOSPHATE × 1 GTP GUANOSINE-5'-TRIPHOSPHATE × 1 MG MAGNESIUM ION × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.9
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.80 Å |
| 7AAV Human pre-Bact-2 spliceosome core structure Deposited 2020-09-04 | Assembly 1 Protein–RNA Heteromer;Protein × 13 PDB declaration: heptadecameric(17) Consistent with all polymers |
Chain K
1–439(439 aa)
|
Not recorded | GTP GUANOSINE-5'-TRIPHOSPHATE × 1 MG MAGNESIUM ION × 1 KGN D-chiro inositol hexakisphosphate × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.9
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 4.20 Å |
| 7ABF Human pre-Bact-1 spliceosome core structure Deposited 2020-09-07 | Assembly 1 Protein–RNA Heteromer;Protein × 12 PDB declaration: pentadecameric(15) Consistent with all polymers |
Chain K
1–439(439 aa)
|
Not recorded | IHP INOSITOL HEXAKISPHOSPHATE × 1 GTP GUANOSINE-5'-TRIPHOSPHATE × 1 MG MAGNESIUM ION × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.9
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.90 Å |
| 7ABG Human pre-Bact-1 spliceosome Deposited 2020-09-07 | Assembly 1 Protein–RNA Heteromer;Protein × 54 PDB declaration: 58-meric(58) Consistent with all polymers |
Chain K
1–439(439 aa)
|
Not recorded | IHP INOSITOL HEXAKISPHOSPHATE × 1 GTP GUANOSINE-5'-TRIPHOSPHATE × 1 MG MAGNESIUM ION × 1 GTG 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.9
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 7.80 Å |
| 7ABI Human pre-Bact-2 spliceosome Deposited 2020-09-07 | Assembly 1 Protein–RNA Heteromer;Protein × 52 PDB declaration: 56-meric(56) Consistent with all polymers |
Chain K
1–439(439 aa)
|
Not recorded | GTP GUANOSINE-5'-TRIPHOSPHATE × 1 MG MAGNESIUM ION × 1 IHP INOSITOL HEXAKISPHOSPHATE × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.9
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 8.00 Å |
| 8H6K Cryo-EM structure of human exon-defined spliceosome in the mature B state. Deposited 2022-10-18 | Assembly 1 Protein–RNA Heteromer;Protein × 58 PDB declaration: 63-meric(63) Consistent with all polymers |
Chain 4K
1–439(439 aa)
|
Not recorded | IHP INOSITOL HEXAKISPHOSPHATE × 1 GTP GUANOSINE-5'-TRIPHOSPHATE × 1 MG MAGNESIUM ION × 1 ZN ZINC ION × 2 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.70 Å |
| 8Q7N cryo-EM structure of the human spliceosomal B complex protomer (tri-snRNP core region) Deposited 2023-08-16 | Assembly 1 Protein–RNA Heteromer;Protein × 17 PDB declaration: 21-meric(21) Consistent with all polymers |
Chain K
1–439(439 aa)
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.9
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.10 Å |
| 8QO9 Cryo-EM structure of a human spliceosomal B complex protomer Deposited 2023-09-28 | Assembly 1 Protein–RNA Heteromer;Protein × 66 PDB declaration: 71-meric(71) Consistent with all polymers |
Chain K
1–439(439 aa)
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.9
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 5.29 Å |
| 8QPE Cryo-EM Structure of Pre-B-like Complex (core part) Deposited 2023-10-01 | Assembly 1 Protein–RNA Heteromer;Protein × 15 PDB declaration: 20-meric(20) Consistent with all polymers |
Chain K
1–439(439 aa)
|
Not recorded | IHP INOSITOL HEXAKISPHOSPHATE × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.9
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.10 Å |
| 8QZS Cryo-EM structure of the cross-exon B-like complex Deposited 2023-10-29 | Assembly 1 Protein–RNA Heteromer;Protein × 61 PDB declaration: 68-meric(68) Consistent with all polymers |
Chain K
1–439(439 aa)
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.9
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 4.10 Å |
| 9R3D Cryo-EM structure of the human pre-Bact-OTS complex (whole map) Deposited 2025-05-04 | Assembly 1 Protein–RNA Heteromer;Protein × 14 PDB declaration: 17-meric(17) Consistent with all polymers |
Chain K
1–439(439 aa)
|
Not recorded | IHP INOSITOL HEXAKISPHOSPHATE × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.9
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.12 Å |
| 9R8V Cryo-EM structure of the human pre-Bact-OTS complex (whole map) Deposited 2025-05-17 | Assembly 1 Protein–RNA Heteromer;Protein × 59 PDB declaration: 63-meric(63) Consistent with all polymers |
Chain K
1–439(439 aa)
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.9
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 8.50 Å |