Current Protein Identity：Q9NYG5
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 2MT5 Isolated Ring domain Deposited 2014-08-13 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
17–84（68 aa）
Fragment：UNP residues 17-84
|
Not recorded | ZN ZINC ION × 3 | SOLUTION NMR |
NMR measurement conditions
pH 7；298 K；Ionic strength (raw mmCIF value) 100；Pressure ambient
NMR sample composition
0.5 mM [U-100% 13C; U-100% 15N] protein_1, 90% H2O/10% D2O | 90% H2O/10% D2O
|
Resolution not provided |
| 4R2Y Crystal structure of APC11 RING domain Deposited 2014-08-13 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
17–84（68 aa）
Fragment：RING domain (UNP Residues 17-84)
|
Not recorded | ZN ZINC ION × 3 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6.5；298 K；16% PEG3350, 0.2 M NaNO3, 0.1 M Bis-Tris, pH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 1.75 Å R-free 0.229 |
| 4R2Y Crystal structure of APC11 RING domain Deposited 2014-08-13 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
17–84（68 aa）
Fragment：RING domain (UNP Residues 17-84)
|
Not recorded | ZN ZINC ION × 3 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6.5；298 K；16% PEG3350, 0.2 M NaNO3, 0.1 M Bis-Tris, pH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 1.75 Å R-free 0.229 |
| 4R2Y Crystal structure of APC11 RING domain Deposited 2014-08-13 | Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain C
17–84（68 aa）
Fragment：RING domain (UNP Residues 17-84)
|
Not recorded | ZN ZINC ION × 3 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6.5；298 K；16% PEG3350, 0.2 M NaNO3, 0.1 M Bis-Tris, pH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 1.75 Å R-free 0.229 |
| 4R2Y Crystal structure of APC11 RING domain Deposited 2014-08-13 | Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain D
17–84（68 aa）
Fragment：RING domain (UNP Residues 17-84)
|
Not recorded | ZN ZINC ION × 3 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6.5；298 K；16% PEG3350, 0.2 M NaNO3, 0.1 M Bis-Tris, pH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 1.75 Å R-free 0.229 |
| 4R2Y Crystal structure of APC11 RING domain Deposited 2014-08-13 | Assembly 5 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count |
Chain A
17–84（68 aa）
Fragment：RING domain (UNP Residues 17-84)
Chain B
17–84（68 aa）
Fragment：RING domain (UNP Residues 17-84)
|
Not recorded | ZN ZINC ION × 12 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6.5；298 K；16% PEG3350, 0.2 M NaNO3, 0.1 M Bis-Tris, pH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 1.75 Å R-free 0.229 |
| 4R2Y Crystal structure of APC11 RING domain Deposited 2014-08-13 | Assembly 6 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count |
Chain C
17–84（68 aa）
Fragment：RING domain (UNP Residues 17-84)
Chain D
17–84（68 aa）
Fragment：RING domain (UNP Residues 17-84)
|
Not recorded | ZN ZINC ION × 12 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6.5；298 K；16% PEG3350, 0.2 M NaNO3, 0.1 M Bis-Tris, pH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 1.75 Å R-free 0.229 |
| 4UI9 Atomic structure of the human Anaphase-Promoting Complex Deposited 2015-03-27 | Assembly 1 Protein heterocomplex Heteromer；Protein × 23 PDB declaration: 23-meric（23） Consistent with protein count |
Chain B
1–84（84 aa）
|
Not recorded | ZN ZINC ION × 5 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.60 Å |
| 5A31 Structure of the human APC-Cdh1-Hsl1-UbcH10 complex. Deposited 2015-05-26 | Assembly 1 Protein heterocomplex Heteromer；Protein × 24 PDB declaration: 24-meric（24） Consistent with protein count |
Chain B
1–84（84 aa）
|
Not recorded | ZN ZINC ION × 3 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 4.30 Å |
| 5G04 Structure of the human APC-Cdc20-Hsl1 complex Deposited 2016-03-16 | Assembly 1 Protein heterocomplex Heteromer；Protein × 21 PDB declaration: 21-meric（21） Consistent with protein count |
Chain B
1–84（84 aa）
|
Not recorded | ZN ZINC ION × 3 | ELECTRON MICROSCOPY |
cryo-EM buffer
20MM HEPES, 150MM NACL, 0. 5MM TCEP；pH 8；20MM HEPES, 150MM NACL, 0. 5MM TCEP
cryo-EM vitrification conditions
Cryogen ETHANE；LIQUID ETHANE
|
Resolution 3.90 Å |
| 5G05 Cryo-EM structure of combined apo phosphorylated APC Deposited 2016-03-16 | Assembly 1 Protein heterocomplex Heteromer；Protein × 20 PDB declaration: eicosameric（20） Consistent with protein count |
Chain B
1–84（84 aa）
|
Not recorded | ZN ZINC ION × 3 | ELECTRON MICROSCOPY |
cryo-EM buffer
20MM HEPES, 150MM NACL, 0. 5MM TCEP；pH 8；20MM HEPES, 150MM NACL, 0. 5MM TCEP
cryo-EM vitrification conditions
Cryogen ETHANE；LIQUID ETHANE
|
Resolution 3.40 Å |
| 5JG6 APC11-Ubv shows role of noncovalent RING-Ubiquitin interactions in processive multiubiquitination and Ubiquitin chain elongation by APC/C Deposited 2016-04-19 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
17–84（68 aa）
|
Not recorded | ZN ZINC ION × 3 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；0.2 M Ammonium acetate, 0.1 M Sodium acetate pH 4.6, 33% PEG4000
|
Resolution 2.00 Å R-free 0.220 |
| 5JG6 APC11-Ubv shows role of noncovalent RING-Ubiquitin interactions in processive multiubiquitination and Ubiquitin chain elongation by APC/C Deposited 2016-04-19 | Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain D
17–84（68 aa）
|
Not recorded | ZN ZINC ION × 3 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；0.2 M Ammonium acetate, 0.1 M Sodium acetate pH 4.6, 33% PEG4000
|
Resolution 2.00 Å R-free 0.220 |
| 5KHR Model of human Anaphase-promoting complex/Cyclosome complex (APC15 deletion mutant) in complex with the E2 UBE2C/UBCH10 poised for ubiquitin ligation to substrate (APC/C-CDC20-substrate-UBE2C) Deposited 2016-06-15 | Assembly 1 Protein heterocomplex Heteromer；Protein × 21 PDB declaration: 21-meric（21） Consistent with protein count |
Chain B
1–84（84 aa）
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 6.10 Å |
| 5KHU Model of human Anaphase-promoting complex/Cyclosome (APC15 deletion mutant), in complex with the Mitotic checkpoint complex (APC/C-CDC20-MCC) based on cryo EM data at 4.8 Angstrom resolution Deposited 2016-06-15 | Assembly 1 Protein heterocomplex Heteromer；Protein × 23 PDB declaration: 23-meric（23） Consistent with protein count |
Chain B
1–84（84 aa）
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 4.80 Å |
| 5L9T Model of human Anaphase-promoting complex/Cyclosome (APC/C-CDH1) with E2 UBE2S poised for polyubiquitination where UBE2S, APC2, and APC11 are modeled into low resolution density Deposited 2016-06-11 | Assembly 1 Insufficient information Heteromer；Protein × 22 PDB declaration: 22-meric（22） Consistent with protein count |
Chain B
1–84（84 aa）
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 6.40 Å |
| 5L9U Model of human Anaphase-promoting complex/Cyclosome (APC/C-CDH1) with a cross linked Ubiquitin variant-substrate-UBE2C (UBCH10) complex representing key features of multiubiquitination Deposited 2016-06-11 | Assembly 1 Insufficient information Heteromer；Protein × 22 PDB declaration: 22-meric（22） Consistent with protein count |
Chain B
1–84（84 aa）
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 6.40 Å |
| 5LCW Cryo-EM structure of the Anaphase-promoting complex/Cyclosome, in complex with the Mitotic checkpoint complex (APC/C-MCC) at 4.2 angstrom resolution Deposited 2016-06-22 | Assembly 1 Protein heterocomplex Heteromer；Protein × 23 PDB declaration: 23-meric（23） Consistent with protein count |
Chain B
1–84（84 aa）
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 4.20 Å |
| 6Q6G Cryo-EM structure of the APC/C-Cdc20-Cdk2-cyclinA2-Cks2 complex, the D1 box class Deposited 2018-12-11 | Assembly 1 Protein heterocomplex Heteromer；Protein × 21 PDB declaration: 21-meric（21） Consistent with protein count |
Chain C
1–84（84 aa）
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 8；20mM Hepes, 150mM NaCl, 0.5mM TCEP
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.20 Å |
| 6Q6H Cryo-EM structure of the APC/C-Cdc20-Cdk2-cyclinA2-Cks2 complex, the D2 box class Deposited 2018-12-11 | Assembly 1 Protein heterocomplex Heteromer；Protein × 21 PDB declaration: 21-meric（21） Consistent with protein count |
Chain C
1–84（84 aa）
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 8；20mM Hepes, 150mM NaCl, 0.5mM TCEP
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.20 Å |
| 6TLJ Cryo-EM structure of the Anaphase-promoting complex/Cyclosome, in complex with the Mitotic checkpoint complex (APC/C-MCC) at 3.8 angstrom resolution Deposited 2019-12-02 | Assembly 1 Protein heterocomplex Heteromer；Protein × 23 PDB declaration: 23-meric（23） Consistent with protein count |
Chain B
1–84（84 aa）
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.80 Å |
| 6TM5 Cryo-EM structure of the Anaphase-promoting complex/Cyclosome, in complex with the Nek2A substrate at 3.9 angstrom resolution Deposited 2019-12-03 | Assembly 1 Protein heterocomplex Heteromer；Protein × 22 PDB declaration: 22-meric（22） Consistent with protein count |
Chain B
1–84（84 aa）
|
Not recorded | ZN ZINC ION × 3 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.90 Å |
| 6TNT SUMOylated apoAPC/C with repositioned APC2 WHB domain Deposited 2019-12-10 | Assembly 1 Protein heterocomplex Heteromer；Protein × 20 PDB declaration: eicosameric（20） Consistent with protein count |
Chain B
1–84（84 aa）
|
Not recorded | ZN ZINC ION × 3 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.78 Å |
| 8PKP Cryo-EM structure of the apo Anaphase-promoting complex/cyclosome (APC/C) at 3.2 Angstrom resolution Deposited 2023-06-27 | Assembly 1 Protein heterocomplex Heteromer；Protein × 19 PDB declaration: 19-meric（19） Consistent with protein count |
Chain C
1–84（84 aa）
|
Not recorded | ZN ZINC ION × 4 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.20 Å |
| 8TAR APC/C-CDH1-UBE2C-Ubiquitin-CyclinB-NTD Deposited 2023-06-27 | Assembly 1 Protein heterocomplex Heteromer；Protein × 22 PDB declaration: 22-meric（22） Consistent with protein count |
Chain C
1–84（84 aa）
|
Not recorded | ZN ZINC ION × 4 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 4.00 Å |
| 8TAU APC/C-CDH1-UBE2C-UBE2S-Ubiquitin-CyclinB Deposited 2023-06-27 | Assembly 1 Protein heterocomplex Heteromer；Protein × 23 PDB declaration: 23-meric（23） Consistent with protein count |
Chain C
1–84（84 aa）
|
Not recorded | ZN ZINC ION × 4 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.50 Å |
| 9GAW High-resolution structure of the Anaphase-promoting complex/cyclosome (APC/C) bound to co-activator Cdh1 Deposited 2024-07-29 | Assembly 1 Protein heterocomplex Heteromer；Protein × 21 PDB declaration: 21-meric（21） Consistent with protein count |
Chain C
1–84（84 aa）
|
Not recorded | ZN ZINC ION × 6 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.90 Å |
| 9N9R Model of APC/C-CDC20-UBE2C from H2A/H2B-bound complex Deposited 2025-02-11 | Assembly 1 Protein heterocomplex Heteromer；Protein × 21 PDB declaration: 21-meric（21） Consistent with protein count |
Chain C
1–84（84 aa）
|
Not recorded | ZN ZINC ION × 4 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE-PROPANE
|
Resolution 3.90 Å |
| 9N9S Model of APC/C-CDC20-UBE2C from H3/H4-bound complex Deposited 2025-02-11 | Assembly 1 Protein heterocomplex Heteromer；Protein × 21 PDB declaration: 21-meric（21） Consistent with protein count |
Chain C
1–84（84 aa）
|
Not recorded | ZN ZINC ION × 4 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE-PROPANE
|
Resolution 3.90 Å |