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3ifn

X-ray structure of amyloid beta peptide:antibody (Abeta1-40:12A11) complex

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Amyloid beta A4 protein

OrganismNot specified

UniProt P05067

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 3 12A11 FAB antibody heavy chain × 1 12A11 FAB antibody light chain × 1 water × 3 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1amb 1amc 1aml 1ba4 1ba6 1bjb 1bjc 1hz3 1iyt 1mwp 1owt 1qcm

64 assemblies; showing the first 12

Homodimer
1aap 2loh 2lz3 2lz4 2mgt 2y3k 2y3k 2y3k 2y3k 3ktm 3ktm 3ktm

18 assemblies; showing the first 12

Homotetramer
2y3j 2y3j 2y3l 3ovj 6rhy 6wxm 6wxm

7 assemblies

Other homooligomers
11en 11eo 11ep 12gb 21fb 2beg 2lmn 2lmo 2lmp 2lmq 2lnq 2m4j

99 assemblies; showing the first 12

Heteromeric or nucleic-acid complex
1brc 1ca0 1ca0 1taw 1x11 1x11 1x11 1zjd 2otk 2r0w 2wk3 2wk3

95 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name A4_HUMAN
Isoform —
PDB entities 3
Chains and sequence ranges Author chain P； PDBConstruct 1–40； UniProt 672–711

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id3ifn
Deposition date deposition_date2009-07-24
Structure title titleX-ray structure of amyloid beta peptide:antibody (Abeta1-40:12A11) complex
Keywords keywordsantibody, amyloid beta peptide, IMMUNE SYSTEM; IMMUNE SYSTEM
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

3ifn__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

3ifn__assembly_1__model_1 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

3ifn__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）26.19 Å
Rg (electron density)25.05 Å
Total Rg25.90 Å
Atom count3389
Residues440
Excluded volume60023 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 3ifn__assembly_1__model_1 trimeric （3） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (4)

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6. Fold Classification (SCOP + CATH) 4 domains

CATH v4.4 (4 domains)

Domain ID domain_id3ifnH01
Class class2 — Mainly Beta
Architecture architecture60 — Sandwich
Topology topology40 — Immunoglobulin-like
Homologous superfamily homologous superfamily10 — Immunoglobulins
Domain ID domain_id3ifnH02
Class class2 — Mainly Beta
Architecture architecture60 — Sandwich
Topology topology40 — Immunoglobulin-like
Homologous superfamily homologous superfamily10 — Immunoglobulins
Domain ID domain_id3ifnL01
Class class2 — Mainly Beta
Architecture architecture60 — Sandwich
Topology topology40 — Immunoglobulin-like
Homologous superfamily homologous superfamily10 — Immunoglobulins
Domain ID domain_id3ifnL02
Class class2 — Mainly Beta
Architecture architecture60 — Sandwich
Topology topology40 — Immunoglobulin-like
Homologous superfamily homologous superfamily10 — Immunoglobulins
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7. Citations (1)