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5x3f

Crystal structure of the YgjG-Protein A-Zpa963-PKA catalytic domain

Method: X-RAY DIFFRACTION Dmax: 131.2 Å Quality: GOOD
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Putrescine aminotransferase,Immunoglobulin G-binding protein A

Staphylococcus aureus

UniProt P38507

State in the Current Structure

Assembly Oligomeric State Construct Mutations and Modifications Ligands, Ions and Associated Components Method and Experimental Conditions Structure Quality
1 Insufficient information Heteromer Protein × 8 PDB declaration: octameric（8） Consistent with protein copy count Chain A； UniProt 220–269 Fragment：UNP RESIDUES 7-453,220-269 Mutation：N222V, G240A Zpa963,cAMP-dependent protein kinase catalytic subunit alpha × 4 （P05132） X-RAY DIFFRACTION X-ray crystallization conditions：VAPOR DIFFUSION；pH 5.5；296 K；91mM MES pH 5.5, 2.33M Na formate Resolution 3.38 Å R-free 0.227

Other States of the Same Protein in the Database

Each row is a biological assembly of the same UniProt protein in another PDB entry. The “Difference from current entry” column identifies evidence-level differences; no tag means the currently parsed fields agree.

Other PDB Difference from Current Entry 5X3F Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Method and Experimental Conditions Structure Quality
1BDC STAPHYLOCOCCUS AUREUS PROTEIN A, IMMUNOGLOBULIN-BINDING B DOMAIN, NMR, 10 STRUCTURES Deposited 1996-06-28 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 212–270（59 aa） Fragment：B DOMAIN
Not recorded No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 5；303 K
Resolution not provided
1BDD STAPHYLOCOCCUS AUREUS PROTEIN A, IMMUNOGLOBULIN-BINDING B DOMAIN, NMR, MINIMIZED AVERAGE STRUCTURE Deposited 1996-06-28 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 212–270（59 aa） Fragment：B DOMAIN
Not recorded No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 5；303 K
Resolution not provided
1EDI STAPHYLOCOCCAL PROTEIN A E-DOMAIN (180), NMR, MINIMIZED AVERAGE STRUCTURE Deposited 1996-10-07 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 37–92（56 aa） Fragment：E-DOMAIN
Not recorded No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 5.7；298 K
Resolution not provided
1EDJ STAPHYLOCOCCAL PROTEIN A E-DOMAIN (180), NMR, 20 STRUCTURES Deposited 1996-10-07 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 37–92（56 aa） Fragment：E-DOMAIN (180)
Not recorded No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 5.7；298 K
Resolution not provided
1EDK STAPHYLOCOCCAL PROTEIN A E-DOMAIN (-60), NMR, MINIMIZED AVERAGE STRUCTURE Deposited 1996-07-22 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 37–92（56 aa） Fragment：E-DOMAIN
Not recorded No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 5.7；298 K
Resolution not provided
1EDL STAPHYLOCOCCAL PROTEIN A E-DOMAIN (-60), NMR, 22 STRUCTURES Deposited 1996-07-22 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 37–92（56 aa） Fragment：E-DOMAIN
Not recorded No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 5.7；298 K
Resolution not provided
1LP1 Protein Z in complex with an in vitro selected affibody Deposited 2002-05-07 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain B 212–269（58 aa） Fragment：RESIDUES 2-58
Mutation：A1V, G29A SO4 SULFATE ION × 4 MG MAGNESIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.5；298 K；MgSO4, MES, pH 6.5, VAPOR DIFFUSION, SITTING DROP, temperature 298K
Resolution 2.30 Å R-free 0.256
1LP1 Protein Z in complex with an in vitro selected affibody Deposited 2002-05-07 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric
Chain B 212–269（58 aa） Fragment：RESIDUES 2-58
Mutation：A1V, G29A SO4 SULFATE ION × 8 MG MAGNESIUM ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.5；298 K；MgSO4, MES, pH 6.5, VAPOR DIFFUSION, SITTING DROP, temperature 298K
Resolution 2.30 Å R-free 0.256
1Q2N REFINED Solution NMR structure of the Z domain of STAPHYLOCOCCAL PROTEIN A Deposited 2003-07-25 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 212–269（58 aa） Fragment：residues 212-269
Not recorded No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 6.5；303 K；Ionic strength (raw mmCIF value) 20 mM NH4OAc；Pressure 1
NMR sample composition 1mM Z domain U-15N,13C; 20mM NH4OAc buffer; 95% H2O, 5% D2O. | 95% H2O/5% D2O
Resolution not provided
1SS1 STAPHYLOCOCCAL PROTEIN A, B-DOMAIN, Y15W MUTANT, NMR, 25 STRUCTURES Deposited 2004-03-23 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 212–270（59 aa） Fragment：B DOMAIN
Mutation：Y15W No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 5.5；298 K；Ionic strength (raw mmCIF value) 100 mM NaCl / 50 mM acetate；Pressure ambient
NMR sample composition 2mM sample, U-13C, U-15N; 50 mM D-acetate buffer, 100 mM NaCl, pH 5.5; 90% H2O, 10% D2O | 90% H20, 10% D20
Resolution not provided
2JWD protein A Deposited 2007-10-09 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 213–269（57 aa） Fragment：B domain
Mutation：Y15W No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 5；298 K；Ionic strength (raw mmCIF value) 100；Pressure ambient
NMR sample composition 20mM sodium acetate, 100mM sodium chloride, 90% H2O/10% D2O | 90% H2O/10% D2O
Resolution not provided
2M5A Protein A binding by an engineered Affibody molecule Deposited 2013-02-19 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 213–269（57 aa）
Not recorded No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 5.6；298 K；Ionic strength (raw mmCIF value) 0.095；Pressure ambient
NMR sample composition 0.5 to 1 mM [U-99% 13C; U-99% 15N] Z domain, 25% molar excess mM ZpA963, 93% H2O/7% D2O | 93% H2O/7% D2O
NMR sample composition 0.5 to 1.0 mM [U-99% 13C; U-99% 15N] ZpA963, 25 5 molar excess mM Z domain, 93% H2O/7% D2O | 93% H2O/7% D2O
Resolution not provided
2SPZ STAPHYLOCOCCAL PROTEIN A, Z-DOMAIN, NMR, 10 STRUCTURES Deposited 1998-07-29 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 212–269（58 aa） Fragment：Z DOMAIN
Mutation：A1V, G29A No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 6.5；303 K；Ionic strength (raw mmCIF value) 10 MILLIMOLAR K2HPO4；Pressure 1
Resolution not provided
3MZW HER2 extracelluar region with affinity matured 3-helix affibody ZHER2:342 Deposited 2010-05-13 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Other combination Heteromer；Protein × 2 PDB declaration: dimeric
Chain B 212–269（58 aa） Fragment：B 4 repeat domain residues 212-269
Mutation：A212V, Q220M, Q221R, F224Y, Y225W, L228A, H229L, E235N, E236Q, R238K, N239R, G240A, Q243R, K246Y NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5；279 K；0.05M sodium chloride, 7.5% PEG3350, 0.1M ammonium acetate, VAPOR DIFFUSION, HANGING DROP, temperature 279K
Resolution 2.90 Å R-free 0.278
4NPD High-resolution structure of C domain of staphylococcal protein A at cryogenic temperature Deposited 2013-11-21 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 270–327（58 aa） Fragment：UNP residues 270-327
Not recorded ZN ZINC ION × 2 SCN THIOCYANATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7；298 K；Na Thiocyanate, PEG 3350, Glycerol, pH 7, VAPOR DIFFUSION, SITTING DROP, temperature 298K
Resolution 0.90 Å R-free 0.130
4NPE High-resolution structure of C domain of staphylococcal protein A at room temperature Deposited 2013-11-21 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 270–327（58 aa） Fragment：UNP residues 270-327
Not recorded ZN ZINC ION × 1 SCN THIOCYANATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7；298 K；Na Thiocyanate, PEG 3350, Glycerol, pH 7, VAPOR DIFFUSION, SITTING DROP, temperature 298K
Resolution 1.42 Å R-free 0.143
4NPF High-resolution structure of two tandem B domains of staphylococcal protein A connected by the conserved linker Deposited 2013-11-21 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain Y 154–269（116 aa） Fragment：UNP residues 212-323
Mutation：W13F, W113F No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6；298 K；Ammonium Sulfate, MES, pH 6, vapor diffusion, sitting drop, temperature 298K
Resolution 1.49 Å R-free 0.185
4NPF High-resolution structure of two tandem B domains of staphylococcal protein A connected by the conserved linker Deposited 2013-11-21 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain X 154–269（116 aa） Fragment：UNP residues 212-323
Mutation：W13F, W113F No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6；298 K；Ammonium Sulfate, MES, pH 6, vapor diffusion, sitting drop, temperature 298K
Resolution 1.49 Å R-free 0.185
4WWI Crystal structure of the C domain of staphylococcal protein A in complex with the Fc fragment of human IgG at 2.3 Angstrom resolution Deposited 2014-11-11 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 270–327（58 aa） Fragment：UNP residues 270-327
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 8；298 K；NaOAc, ammonium sulfate, PEG 5K MME, glycerol
Resolution 2.31 Å R-free 0.251
4WWI Crystal structure of the C domain of staphylococcal protein A in complex with the Fc fragment of human IgG at 2.3 Angstrom resolution Deposited 2014-11-11 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain B 270–327（58 aa） Fragment：UNP residues 270-327
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 8；298 K；NaOAc, ammonium sulfate, PEG 5K MME, glycerol
Resolution 2.31 Å R-free 0.251
4WWI Crystal structure of the C domain of staphylococcal protein A in complex with the Fc fragment of human IgG at 2.3 Angstrom resolution Deposited 2014-11-11 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 3 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain C 270–327（58 aa） Fragment：UNP residues 270-327
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 8；298 K；NaOAc, ammonium sulfate, PEG 5K MME, glycerol
Resolution 2.31 Å R-free 0.251
4ZMD C domain of staphylococcal protein A mutant - Q9W Deposited 2015-05-03 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 270–327（58 aa） Fragment：UNP residues 270-327
Mutation：Q9W No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；298 K；PEG 3350, sodium thiocyanate
Resolution 1.87 Å R-free 0.256
4ZMD C domain of staphylococcal protein A mutant - Q9W Deposited 2015-05-03 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain B 270–327（58 aa） Fragment：UNP residues 270-327
Mutation：Q9W No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；298 K；PEG 3350, sodium thiocyanate
Resolution 1.87 Å R-free 0.256
4ZNC Fc fragment of human IgG in complex with the C domain of staphylococcal protein A mutant - Q9W Deposited 2015-05-04 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 270–327（58 aa） Fragment：UNP residues 270-327
Mutation：Q9W No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 5.6；298 K；PEG 5000 MME, ammonium sulfate, sodium acetate
Resolution 2.28 Å R-free 0.242
4ZNC Fc fragment of human IgG in complex with the C domain of staphylococcal protein A mutant - Q9W Deposited 2015-05-04 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain B 270–327（58 aa） Fragment：UNP residues 270-327
Mutation：Q9W No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 5.6；298 K；PEG 5000 MME, ammonium sulfate, sodium acetate
Resolution 2.28 Å R-free 0.242
4ZNC Fc fragment of human IgG in complex with the C domain of staphylococcal protein A mutant - Q9W Deposited 2015-05-04 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 3 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain C 270–327（58 aa） Fragment：UNP residues 270-327
Mutation：Q9W No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 5.6；298 K；PEG 5000 MME, ammonium sulfate, sodium acetate
Resolution 2.28 Å R-free 0.242
5CBN Fusion protein of mbp3-16 and B4 domain of protein A from staphylococcal aureus with chemical cross-linker EY-CBS Deposited 2015-07-01 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 218–269（52 aa） Fragment：B4 domain (UNP RESIDUES 218-269)
Mutation：E126A, N129A, E133C, G147A EYC 2,2'-ethyne-1,2-diylbis{5-[(chloroacetyl)amino]benzenesulfonic acid} × 1 X-RAY DIFFRACTION
X-ray crystallization conditions EVAPORATION；pH 6.5；277 K；36% w/v PEG 2000, 0.2M magnesium chloride hexahydrate
Resolution 2.30 Å R-free 0.260
5CBO Fusion protein of mbp3-16 and B4 domain of protein A from staphylococcal aureus Deposited 2015-07-01 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 102–153（52 aa） Fragment：B4 domain (UNP RESIDUES 102-153)
Mutation：D1219A, S1222A, E1226C, N1229H, E1236A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions EVAPORATION；pH 5.5；298 K；34% w/v PPG P-400 10mM Hexaamine cobalt(III) chloride
Resolution 2.80 Å R-free 0.254
5CBO Fusion protein of mbp3-16 and B4 domain of protein A from staphylococcal aureus Deposited 2015-07-01 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 10 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain J 102–153（52 aa） Fragment：B4 domain (UNP RESIDUES 102-153)
Mutation：D1219A, S1222A, E1226C, N1229H, E1236A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions EVAPORATION；pH 5.5；298 K；34% w/v PPG P-400 10mM Hexaamine cobalt(III) chloride
Resolution 2.80 Å R-free 0.254
5CBO Fusion protein of mbp3-16 and B4 domain of protein A from staphylococcal aureus Deposited 2015-07-01 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 11 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain K 102–153（52 aa） Fragment：B4 domain (UNP RESIDUES 102-153)
Mutation：D1219A, S1222A, E1226C, N1229H, E1236A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions EVAPORATION；pH 5.5；298 K；34% w/v PPG P-400 10mM Hexaamine cobalt(III) chloride
Resolution 2.80 Å R-free 0.254
5CBO Fusion protein of mbp3-16 and B4 domain of protein A from staphylococcal aureus Deposited 2015-07-01 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 12 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain L 102–153（52 aa） Fragment：B4 domain (UNP RESIDUES 102-153)
Mutation：D1219A, S1222A, E1226C, N1229H, E1236A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions EVAPORATION；pH 5.5；298 K；34% w/v PPG P-400 10mM Hexaamine cobalt(III) chloride
Resolution 2.80 Å R-free 0.254
5CBO Fusion protein of mbp3-16 and B4 domain of protein A from staphylococcal aureus Deposited 2015-07-01 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain B 102–153（52 aa） Fragment：B4 domain (UNP RESIDUES 102-153)
Mutation：D1219A, S1222A, E1226C, N1229H, E1236A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions EVAPORATION；pH 5.5；298 K；34% w/v PPG P-400 10mM Hexaamine cobalt(III) chloride
Resolution 2.80 Å R-free 0.254
5CBO Fusion protein of mbp3-16 and B4 domain of protein A from staphylococcal aureus Deposited 2015-07-01 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain C 102–153（52 aa） Fragment：B4 domain (UNP RESIDUES 102-153)
Mutation：D1219A, S1222A, E1226C, N1229H, E1236A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions EVAPORATION；pH 5.5；298 K；34% w/v PPG P-400 10mM Hexaamine cobalt(III) chloride
Resolution 2.80 Å R-free 0.254
5CBO Fusion protein of mbp3-16 and B4 domain of protein A from staphylococcal aureus Deposited 2015-07-01 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain D 102–153（52 aa） Fragment：B4 domain (UNP RESIDUES 102-153)
Mutation：D1219A, S1222A, E1226C, N1229H, E1236A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions EVAPORATION；pH 5.5；298 K；34% w/v PPG P-400 10mM Hexaamine cobalt(III) chloride
Resolution 2.80 Å R-free 0.254
5CBO Fusion protein of mbp3-16 and B4 domain of protein A from staphylococcal aureus Deposited 2015-07-01 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 5 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain E 102–153（52 aa） Fragment：B4 domain (UNP RESIDUES 102-153)
Mutation：D1219A, S1222A, E1226C, N1229H, E1236A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions EVAPORATION；pH 5.5；298 K；34% w/v PPG P-400 10mM Hexaamine cobalt(III) chloride
Resolution 2.80 Å R-free 0.254
5CBO Fusion protein of mbp3-16 and B4 domain of protein A from staphylococcal aureus Deposited 2015-07-01 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 6 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain F 102–153（52 aa） Fragment：B4 domain (UNP RESIDUES 102-153)
Mutation：D1219A, S1222A, E1226C, N1229H, E1236A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions EVAPORATION；pH 5.5；298 K；34% w/v PPG P-400 10mM Hexaamine cobalt(III) chloride
Resolution 2.80 Å R-free 0.254
5CBO Fusion protein of mbp3-16 and B4 domain of protein A from staphylococcal aureus Deposited 2015-07-01 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 7 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain G 102–153（52 aa） Fragment：B4 domain (UNP RESIDUES 102-153)
Mutation：D1219A, S1222A, E1226C, N1229H, E1236A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions EVAPORATION；pH 5.5；298 K；34% w/v PPG P-400 10mM Hexaamine cobalt(III) chloride
Resolution 2.80 Å R-free 0.254
5CBO Fusion protein of mbp3-16 and B4 domain of protein A from staphylococcal aureus Deposited 2015-07-01 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 8 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain H 102–153（52 aa） Fragment：B4 domain (UNP RESIDUES 102-153)
Mutation：D1219A, S1222A, E1226C, N1229H, E1236A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions EVAPORATION；pH 5.5；298 K；34% w/v PPG P-400 10mM Hexaamine cobalt(III) chloride
Resolution 2.80 Å R-free 0.254
5CBO Fusion protein of mbp3-16 and B4 domain of protein A from staphylococcal aureus Deposited 2015-07-01 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 9 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain I 102–153（52 aa） Fragment：B4 domain (UNP RESIDUES 102-153)
Mutation：D1219A, S1222A, E1226C, N1229H, E1236A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions EVAPORATION；pH 5.5；298 K；34% w/v PPG P-400 10mM Hexaamine cobalt(III) chloride
Resolution 2.80 Å R-free 0.254
5COC Fusion protein of human calmodulin and B4 domain of protein A from staphylococcal aureus Deposited 2015-07-20 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Monomer；Protein × 1 PDB declaration: monomeric
Chain A 213–267（55 aa） Fragment：B4 domain (UNP RESIDUES 213-267),N-terminal (UNP RESIDUES 5-78)
Mutation：G240A, K261C, L1005A, T1006A, Q1009C CA CALCIUM ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions EVAPORATION；298 K；10% w/v PEG 1000, 10% w/v PEG 8000
Resolution 2.67 Å R-free 0.259
5EWX Fusion protein of T4 lysozyme and B4 domain of protein A from staphylococcal aureus with chemical cross-linker EY-CBS Deposited 2015-11-22 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Monomer；Protein × 1 PDB declaration: monomeric
Chain A 212–266（55 aa） Fragment：UNP RESIDUES 1-35, 219-266, 38-164
Mutation：A1212V, G1240A, E1258C, K1261A, L1262A, N40C, C54T, C97A, K162A EYC 2,2'-ethyne-1,2-diylbis{5-[(chloroacetyl)amino]benzenesulfonic acid} × 1 X-RAY DIFFRACTION
X-ray crystallization conditions EVAPORATION；pH 7.5；277 K；1.84M Na/K Phosphate, pH 7.5
Resolution 2.60 Å R-free 0.253
5EWX Fusion protein of T4 lysozyme and B4 domain of protein A from staphylococcal aureus with chemical cross-linker EY-CBS Deposited 2015-11-22 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Insufficient information Monomer；Protein × 1 PDB declaration: monomeric
Chain B 212–266（55 aa） Fragment：UNP RESIDUES 1-35, 219-266, 38-164
Mutation：A1212V, G1240A, E1258C, K1261A, L1262A, N40C, C54T, C97A, K162A EYC 2,2'-ethyne-1,2-diylbis{5-[(chloroacetyl)amino]benzenesulfonic acid} × 1 X-RAY DIFFRACTION
X-ray crystallization conditions EVAPORATION；pH 7.5；277 K；1.84M Na/K Phosphate, pH 7.5
Resolution 2.60 Å R-free 0.253
5H75 Crystal structure of the MrsD-Protein A fusion protein Deposited 2016-11-17 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Homooligomer；Protein × 12 PDB declaration: dodecameric
Chain A 223–269（47 aa） Fragment：UNP RESIDUES 1-184,223-269
Chain B 223–269（47 aa） Fragment：UNP RESIDUES 1-184,223-269
Chain C 223–269（47 aa） Fragment：UNP RESIDUES 1-184,223-269
Chain D 223–269（47 aa） Fragment：UNP RESIDUES 1-184,223-269
Mutation：K182Q,G240A Mutation：K182Q,G240A Mutation：K182Q,G240A Mutation：K182Q,G240A FAD FLAVIN-ADENINE DINUCLEOTIDE × 12 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 5.5；277 K；0.94M sodium citrate pH 5.5
Resolution 2.74 Å R-free 0.243
5H76 Crystal structure of the DARPin-Protein A fusion protein Deposited 2016-11-17 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 235–267（33 aa） Fragment：RESIDUES 9-176,177-209 (UNP RESIDUES 235-267)
Mutation：G182A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 9.5；296 K；0.63M sodium potassium phosphate pH 9.5
Resolution 2.60 Å R-free 0.250
5H76 Crystal structure of the DARPin-Protein A fusion protein Deposited 2016-11-17 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain B 235–267（33 aa） Fragment：RESIDUES 9-176,177-209 (UNP RESIDUES 235-267)
Mutation：G182A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 9.5；296 K；0.63M sodium potassium phosphate pH 9.5
Resolution 2.60 Å R-free 0.250
5H76 Crystal structure of the DARPin-Protein A fusion protein Deposited 2016-11-17 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain C 235–267（33 aa） Fragment：RESIDUES 9-176,177-209 (UNP RESIDUES 235-267)
Mutation：G182A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 9.5；296 K；0.63M sodium potassium phosphate pH 9.5
Resolution 2.60 Å R-free 0.250
5H77 Crystal structure of the PKA-protein A fusion protein Deposited 2016-11-17 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 220–268（49 aa） Fragment：UNP RESIDUES 5-41,UNP RESIDUES 220-268
Chain B 220–268（49 aa） Fragment：UNP RESIDUES 5-41,UNP RESIDUES 220-268
Mutation：G222A, G240A Mutation：G222A, G240A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 4.5；296 K；0.1M sodium acetate pH 4.5, 0.68M sodium citrate pH 4.5
Resolution 3.20 Å R-free 0.284
5H77 Crystal structure of the PKA-protein A fusion protein Deposited 2016-11-17 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 2 Insufficient information Homooligomer；Protein × 2 PDB declaration: dimeric
Chain C 220–268（49 aa） Fragment：UNP RESIDUES 5-41,UNP RESIDUES 220-268
Chain D 220–268（49 aa） Fragment：UNP RESIDUES 5-41,UNP RESIDUES 220-268
Mutation：G222A, G240A Mutation：G222A, G240A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 4.5；296 K；0.1M sodium acetate pH 4.5, 0.68M sodium citrate pH 4.5
Resolution 3.20 Å R-free 0.284
5H77 Crystal structure of the PKA-protein A fusion protein Deposited 2016-11-17 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 3 Insufficient information Homooligomer；Protein × 2 PDB declaration: dimeric
Chain E 220–268（49 aa） Fragment：UNP RESIDUES 5-41,UNP RESIDUES 220-268
Chain F 220–268（49 aa） Fragment：UNP RESIDUES 5-41,UNP RESIDUES 220-268
Mutation：G222A, G240A Mutation：G222A, G240A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 4.5；296 K；0.1M sodium acetate pH 4.5, 0.68M sodium citrate pH 4.5
Resolution 3.20 Å R-free 0.284
5H77 Crystal structure of the PKA-protein A fusion protein Deposited 2016-11-17 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 4 Insufficient information Homooligomer；Protein × 2 PDB declaration: dimeric
Chain G 220–268（49 aa） Fragment：UNP RESIDUES 5-41,UNP RESIDUES 220-268
Chain H 220–268（49 aa） Fragment：UNP RESIDUES 5-41,UNP RESIDUES 220-268
Mutation：G222A, G240A Mutation：G222A, G240A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 4.5；296 K；0.1M sodium acetate pH 4.5, 0.68M sodium citrate pH 4.5
Resolution 3.20 Å R-free 0.284
5H77 Crystal structure of the PKA-protein A fusion protein Deposited 2016-11-17 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 5 Insufficient information Homooligomer；Protein × 2 PDB declaration: dimeric
Chain I 220–268（49 aa） Fragment：UNP RESIDUES 5-41,UNP RESIDUES 220-268
Chain J 220–268（49 aa） Fragment：UNP RESIDUES 5-41,UNP RESIDUES 220-268
Mutation：G222A, G240A Mutation：G222A, G240A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 4.5；296 K；0.1M sodium acetate pH 4.5, 0.68M sodium citrate pH 4.5
Resolution 3.20 Å R-free 0.284
5H77 Crystal structure of the PKA-protein A fusion protein Deposited 2016-11-17 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 6 Insufficient information Homooligomer；Protein × 2 PDB declaration: dimeric
Chain K 220–268（49 aa） Fragment：UNP RESIDUES 5-41,UNP RESIDUES 220-268
Chain L 220–268（49 aa） Fragment：UNP RESIDUES 5-41,UNP RESIDUES 220-268
Mutation：G222A, G240A Mutation：G222A, G240A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 4.5；296 K；0.1M sodium acetate pH 4.5, 0.68M sodium citrate pH 4.5
Resolution 3.20 Å R-free 0.284
5H79 Crystal structure of a repeat protein with three Protein A repeat module Deposited 2016-11-17 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain D 217–263（47 aa） Fragment：UNP RESIDUES 217-263,UNP RESIDUES 219-263,UNP RESIDUES 219-268
Chain D 219–263（45 aa） Fragment：UNP RESIDUES 217-263,UNP RESIDUES 219-263,UNP RESIDUES 219-268
Chain D 219–268（50 aa） Fragment：UNP RESIDUES 217-263,UNP RESIDUES 219-263,UNP RESIDUES 219-268
Mutation：G59A, N131A, G149A Mutation：G59A, N131A, G149A Mutation：G59A, N131A, G149A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 4.5；296 K；0.1M sodium acetate pH 4.5, 13.5%(w/v) PEG 1000
Resolution 2.70 Å R-free 0.278
5H79 Crystal structure of a repeat protein with three Protein A repeat module Deposited 2016-11-17 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain C 217–263（47 aa） Fragment：UNP RESIDUES 217-263,UNP RESIDUES 219-263,UNP RESIDUES 219-268
Chain C 219–263（45 aa） Fragment：UNP RESIDUES 217-263,UNP RESIDUES 219-263,UNP RESIDUES 219-268
Chain C 219–268（50 aa） Fragment：UNP RESIDUES 217-263,UNP RESIDUES 219-263,UNP RESIDUES 219-268
Mutation：G59A, N131A, G149A Mutation：G59A, N131A, G149A Mutation：G59A, N131A, G149A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 4.5；296 K；0.1M sodium acetate pH 4.5, 13.5%(w/v) PEG 1000
Resolution 2.70 Å R-free 0.278
5H7A Crystal structure of a repeat protein with four Protein A repeat module Deposited 2016-11-17 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain C 215–263（49 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Chain C 219–263（45 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Chain C 219–267（49 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Mutation：G59A, G104A, G149A, G194A Mutation：G59A, G104A, G149A, G194A Mutation：G59A, G104A, G149A, G194A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 4.5；296 K；0.1M sodium acetate pH 4.5, 43.2% (w/v) PEG 1000
Resolution 2.70 Å R-free 0.285
5H7A Crystal structure of a repeat protein with four Protein A repeat module Deposited 2016-11-17 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 10 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain J 215–263（49 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Chain J 219–263（45 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Chain J 219–267（49 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Mutation：G59A, G104A, G149A, G194A Mutation：G59A, G104A, G149A, G194A Mutation：G59A, G104A, G149A, G194A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 4.5；296 K；0.1M sodium acetate pH 4.5, 43.2% (w/v) PEG 1000
Resolution 2.70 Å R-free 0.285
5H7A Crystal structure of a repeat protein with four Protein A repeat module Deposited 2016-11-17 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 11 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain K 215–263（49 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Chain K 219–263（45 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Chain K 219–267（49 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Mutation：G59A, G104A, G149A, G194A Mutation：G59A, G104A, G149A, G194A Mutation：G59A, G104A, G149A, G194A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 4.5；296 K；0.1M sodium acetate pH 4.5, 43.2% (w/v) PEG 1000
Resolution 2.70 Å R-free 0.285
5H7A Crystal structure of a repeat protein with four Protein A repeat module Deposited 2016-11-17 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 12 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain L 215–263（49 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Chain L 219–263（45 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Chain L 219–267（49 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Mutation：G59A, G104A, G149A, G194A Mutation：G59A, G104A, G149A, G194A Mutation：G59A, G104A, G149A, G194A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 4.5；296 K；0.1M sodium acetate pH 4.5, 43.2% (w/v) PEG 1000
Resolution 2.70 Å R-free 0.285
5H7A Crystal structure of a repeat protein with four Protein A repeat module Deposited 2016-11-17 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 215–263（49 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Chain A 219–263（45 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Chain A 219–267（49 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Mutation：G59A, G104A, G149A, G194A Mutation：G59A, G104A, G149A, G194A Mutation：G59A, G104A, G149A, G194A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 4.5；296 K；0.1M sodium acetate pH 4.5, 43.2% (w/v) PEG 1000
Resolution 2.70 Å R-free 0.285
5H7A Crystal structure of a repeat protein with four Protein A repeat module Deposited 2016-11-17 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain D 215–263（49 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Chain D 219–263（45 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Chain D 219–267（49 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Mutation：G59A, G104A, G149A, G194A Mutation：G59A, G104A, G149A, G194A Mutation：G59A, G104A, G149A, G194A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 4.5；296 K；0.1M sodium acetate pH 4.5, 43.2% (w/v) PEG 1000
Resolution 2.70 Å R-free 0.285
5H7A Crystal structure of a repeat protein with four Protein A repeat module Deposited 2016-11-17 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain B 215–263（49 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Chain B 219–263（45 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Chain B 219–267（49 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Mutation：G59A, G104A, G149A, G194A Mutation：G59A, G104A, G149A, G194A Mutation：G59A, G104A, G149A, G194A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 4.5；296 K；0.1M sodium acetate pH 4.5, 43.2% (w/v) PEG 1000
Resolution 2.70 Å R-free 0.285
5H7A Crystal structure of a repeat protein with four Protein A repeat module Deposited 2016-11-17 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 5 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain E 215–263（49 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Chain E 219–263（45 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Chain E 219–267（49 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Mutation：G59A, G104A, G149A, G194A Mutation：G59A, G104A, G149A, G194A Mutation：G59A, G104A, G149A, G194A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 4.5；296 K；0.1M sodium acetate pH 4.5, 43.2% (w/v) PEG 1000
Resolution 2.70 Å R-free 0.285
5H7A Crystal structure of a repeat protein with four Protein A repeat module Deposited 2016-11-17 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 6 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain F 215–263（49 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Chain F 219–263（45 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Chain F 219–267（49 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Mutation：G59A, G104A, G149A, G194A Mutation：G59A, G104A, G149A, G194A Mutation：G59A, G104A, G149A, G194A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 4.5；296 K；0.1M sodium acetate pH 4.5, 43.2% (w/v) PEG 1000
Resolution 2.70 Å R-free 0.285
5H7A Crystal structure of a repeat protein with four Protein A repeat module Deposited 2016-11-17 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 7 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain G 215–263（49 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Chain G 219–263（45 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Chain G 219–267（49 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Mutation：G59A, G104A, G149A, G194A Mutation：G59A, G104A, G149A, G194A Mutation：G59A, G104A, G149A, G194A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 4.5；296 K；0.1M sodium acetate pH 4.5, 43.2% (w/v) PEG 1000
Resolution 2.70 Å R-free 0.285
5H7A Crystal structure of a repeat protein with four Protein A repeat module Deposited 2016-11-17 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 8 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain H 215–263（49 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Chain H 219–263（45 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Chain H 219–267（49 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Mutation：G59A, G104A, G149A, G194A Mutation：G59A, G104A, G149A, G194A Mutation：G59A, G104A, G149A, G194A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 4.5；296 K；0.1M sodium acetate pH 4.5, 43.2% (w/v) PEG 1000
Resolution 2.70 Å R-free 0.285
5H7A Crystal structure of a repeat protein with four Protein A repeat module Deposited 2016-11-17 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 9 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain I 215–263（49 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Chain I 219–263（45 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Chain I 219–267（49 aa） Fragment：UNP RESIDUES 215-263, 219-263, 219-263, 219-267
Mutation：G59A, G104A, G149A, G194A Mutation：G59A, G104A, G149A, G194A Mutation：G59A, G104A, G149A, G194A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 4.5；296 K；0.1M sodium acetate pH 4.5, 43.2% (w/v) PEG 1000
Resolution 2.70 Å R-free 0.285
5H7B Crystal structure of a repeat protein with five Protein A repeat modules Deposited 2016-11-17 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 215–263（49 aa） Fragment：UNP RESIDUES 215-263,219-263,219-263,219-263,219-267
Chain A 219–263（45 aa） Fragment：UNP RESIDUES 215-263,219-263,219-263,219-263,219-267
Chain A 219–267（49 aa） Fragment：UNP RESIDUES 215-263,219-263,219-263,219-263,219-267
Mutation：G59A, G104A, G149A, 1G94A, G239A Mutation：G59A, G104A, G149A, 1G94A, G239A Mutation：G59A, G104A, G149A, 1G94A, G239A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 4.5；296 K；0.1M sodium acetate pH 4.5, 27.3% PEG MME 2000
Resolution 3.10 Å R-free 0.315
5H7B Crystal structure of a repeat protein with five Protein A repeat modules Deposited 2016-11-17 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain B 215–263（49 aa） Fragment：UNP RESIDUES 215-263,219-263,219-263,219-263,219-267
Chain B 219–263（45 aa） Fragment：UNP RESIDUES 215-263,219-263,219-263,219-263,219-267
Chain B 219–267（49 aa） Fragment：UNP RESIDUES 215-263,219-263,219-263,219-263,219-267
Mutation：G59A, G104A, G149A, 1G94A, G239A Mutation：G59A, G104A, G149A, 1G94A, G239A Mutation：G59A, G104A, G149A, 1G94A, G239A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 4.5；296 K；0.1M sodium acetate pH 4.5, 27.3% PEG MME 2000
Resolution 3.10 Å R-free 0.315
5H7C Crystal structure of a repeat protein with two Protein A-DHR14 repeat modules Deposited 2016-11-17 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 215–267（53 aa） Fragment：UNP RESIDUES 215-267,219-267
Chain A 219–267（49 aa） Fragment：UNP RESIDUES 215-267,219-267
Mutation：10 mutations Mutation：10 mutations No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 8；296 K；0.1M Tris pH 8.0, 33.75%(w/v) PEG MME 2000
Resolution 2.70 Å R-free 0.262
5H7C Crystal structure of a repeat protein with two Protein A-DHR14 repeat modules Deposited 2016-11-17 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain C 215–267（53 aa） Fragment：UNP RESIDUES 215-267,219-267
Chain C 219–267（49 aa） Fragment：UNP RESIDUES 215-267,219-267
Mutation：10 mutations Mutation：10 mutations No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 8；296 K；0.1M Tris pH 8.0, 33.75%(w/v) PEG MME 2000
Resolution 2.70 Å R-free 0.262
5H7D Crystal structure of the YgjG-protein A-Zpa963-calmodulin complex Deposited 2016-11-17 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 8 PDB declaration: octameric
Chain A 220–267（48 aa） Fragment：UNP RESIDUES 7-453,UNP RESIDUES 220-267
Chain B 220–267（48 aa） Fragment：UNP RESIDUES 7-453,UNP RESIDUES 220-267
Chain C 220–267（48 aa） Fragment：UNP RESIDUES 7-453,UNP RESIDUES 220-267
Chain D 220–267（48 aa） Fragment：UNP RESIDUES 7-453,UNP RESIDUES 220-267
Mutation：N222V, G240A Mutation：N222V, G240A Mutation：N222V, G240A Mutation：N222V, G240A CA CALCIUM ION × 8 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 7.5；296 K；0.1M HEPES pH 7.5, 20.7% PEG 300, 99mM calcium chloride
Resolution 2.57 Å R-free 0.241
5H7D Crystal structure of the YgjG-protein A-Zpa963-calmodulin complex Deposited 2016-11-17 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Insufficient information Heteromer；Protein × 8 PDB declaration: octameric
Chain I 220–267（48 aa） Fragment：UNP RESIDUES 7-453,UNP RESIDUES 220-267
Chain J 220–267（48 aa） Fragment：UNP RESIDUES 7-453,UNP RESIDUES 220-267
Chain M 220–267（48 aa） Fragment：UNP RESIDUES 7-453,UNP RESIDUES 220-267
Chain N 220–267（48 aa） Fragment：UNP RESIDUES 7-453,UNP RESIDUES 220-267
Mutation：N222V, G240A Mutation：N222V, G240A Mutation：N222V, G240A Mutation：N222V, G240A CA CALCIUM ION × 8 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 7.5；296 K；0.1M HEPES pH 7.5, 20.7% PEG 300, 99mM calcium chloride
Resolution 2.57 Å R-free 0.241
5XBY Crystal structure of the PKA-Protein A fusion protein (end-to-end fusion) Deposited 2017-03-21 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 217–269（53 aa） Fragment：UNP RESIDUES 5-44,UNP RESIDUES 217-269
Chain B 217–269（53 aa） Fragment：UNP RESIDUES 5-44,UNP RESIDUES 217-269
Mutation：G240A Mutation：G240A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 8.5；296 K；100mM Tris pH 8.5, 2.16M Sodium formate
Resolution 3.25 Å R-free 0.307
5XBY Crystal structure of the PKA-Protein A fusion protein (end-to-end fusion) Deposited 2017-03-21 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 2 Insufficient information Homooligomer；Protein × 2 PDB declaration: dimeric
Chain C 217–269（53 aa） Fragment：UNP RESIDUES 5-44,UNP RESIDUES 217-269
Chain D 217–269（53 aa） Fragment：UNP RESIDUES 5-44,UNP RESIDUES 217-269
Mutation：G240A Mutation：G240A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 8.5；296 K；100mM Tris pH 8.5, 2.16M Sodium formate
Resolution 3.25 Å R-free 0.307
6KRV Crystal structure of mouse IgG2b Fc complexed with B domain of Protein A Deposited 2019-08-22 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Other combination Heteromer；Protein × 3 PDB declaration: trimeric
Chain D 212–269（58 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7；293 K；60% (v/v) Tacsimate (pH 7.0)
Resolution 3.30 Å R-free 0.250
6KRV Crystal structure of mouse IgG2b Fc complexed with B domain of Protein A Deposited 2019-08-22 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 2 Other combination Heteromer；Protein × 3 PDB declaration: trimeric
Chain D 212–269（58 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7；293 K；60% (v/v) Tacsimate (pH 7.0)
Resolution 3.30 Å R-free 0.250
7EOY Engineered Hepatitis B virus core antigen T=3 Deposited 2021-04-24 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Homooligomer；Protein × 180 PDB declaration: 180-meric
Chain A 212–269（58 aa）
Chain B 212–269（58 aa）
Chain C 212–269（58 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.60 Å
7EOY Engineered Hepatitis B virus core antigen T=3 Deposited 2021-04-24 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 2 Insufficient information Homooligomer；Protein × 3 PDB declaration: trimeric
Chain A 212–269（58 aa）
Chain B 212–269（58 aa）
Chain C 212–269（58 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.60 Å
7EOY Engineered Hepatitis B virus core antigen T=3 Deposited 2021-04-24 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 3 Insufficient information Homooligomer；Protein × 15 PDB declaration: pentadecameric
Chain A 212–269（58 aa）
Chain B 212–269（58 aa）
Chain C 212–269（58 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.60 Å
7EOY Engineered Hepatitis B virus core antigen T=3 Deposited 2021-04-24 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 4 Insufficient information Homooligomer；Protein × 18 PDB declaration: octadecameric
Chain A 212–269（58 aa）
Chain B 212–269（58 aa）
Chain C 212–269（58 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.60 Å
7EOY Engineered Hepatitis B virus core antigen T=3 Deposited 2021-04-24 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 5 Insufficient information Homooligomer；Protein × 3 PDB declaration: trimeric
Chain A 212–269（58 aa）
Chain B 212–269（58 aa）
Chain C 212–269（58 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.60 Å
7EP6 Engineered Hepatitis B virus core antigen T=4 Deposited 2021-04-26 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Homooligomer；Protein × 240 PDB declaration: 240-meric
Chain A 212–269（58 aa）
Chain B 212–269（58 aa）
Chain C 212–269（58 aa）
Chain D 212–269（58 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.86 Å
7EP6 Engineered Hepatitis B virus core antigen T=4 Deposited 2021-04-26 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 2 Insufficient information Homooligomer；Protein × 4 PDB declaration: tetrameric
Chain A 212–269（58 aa）
Chain B 212–269（58 aa）
Chain C 212–269（58 aa）
Chain D 212–269（58 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.86 Å
7EP6 Engineered Hepatitis B virus core antigen T=4 Deposited 2021-04-26 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 3 Insufficient information Homooligomer；Protein × 20 PDB declaration: eicosameric
Chain A 212–269（58 aa）
Chain B 212–269（58 aa）
Chain C 212–269（58 aa）
Chain D 212–269（58 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.86 Å
7EP6 Engineered Hepatitis B virus core antigen T=4 Deposited 2021-04-26 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 4 Insufficient information Homooligomer；Protein × 24 PDB declaration: 24-meric
Chain A 212–269（58 aa）
Chain B 212–269（58 aa）
Chain C 212–269（58 aa）
Chain D 212–269（58 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.86 Å
7EP6 Engineered Hepatitis B virus core antigen T=4 Deposited 2021-04-26 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 5 Insufficient information Homooligomer；Protein × 4 PDB declaration: tetrameric
Chain A 212–269（58 aa）
Chain B 212–269（58 aa）
Chain C 212–269（58 aa）
Chain D 212–269（58 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.86 Å
7FDJ Engineered Hepatitis B virus core antigen with short linker T=4 Deposited 2021-07-16 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Homooligomer；Protein × 240 PDB declaration: 240-meric
Chain A 212–269（58 aa）
Chain B 212–269（58 aa）
Chain C 212–269（58 aa）
Chain D 212–269（58 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.40 Å
7FDJ Engineered Hepatitis B virus core antigen with short linker T=4 Deposited 2021-07-16 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 2 Insufficient information Homooligomer；Protein × 4 PDB declaration: tetrameric
Chain A 212–269（58 aa）
Chain B 212–269（58 aa）
Chain C 212–269（58 aa）
Chain D 212–269（58 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.40 Å
7FDJ Engineered Hepatitis B virus core antigen with short linker T=4 Deposited 2021-07-16 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 3 Insufficient information Homooligomer；Protein × 20 PDB declaration: eicosameric
Chain A 212–269（58 aa）
Chain B 212–269（58 aa）
Chain C 212–269（58 aa）
Chain D 212–269（58 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.40 Å
7FDJ Engineered Hepatitis B virus core antigen with short linker T=4 Deposited 2021-07-16 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 4 Insufficient information Homooligomer；Protein × 24 PDB declaration: 24-meric
Chain A 212–269（58 aa）
Chain B 212–269（58 aa）
Chain C 212–269（58 aa）
Chain D 212–269（58 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.40 Å
7FDJ Engineered Hepatitis B virus core antigen with short linker T=4 Deposited 2021-07-16 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 5 Insufficient information Homooligomer；Protein × 4 PDB declaration: tetrameric
Chain A 212–269（58 aa）
Chain B 212–269（58 aa）
Chain C 212–269（58 aa）
Chain D 212–269（58 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.40 Å
7NHA 1918 H1N1 Viral influenza polymerase heterotrimer - Endonuclease and priming loop ordered (Class2a) Deposited 2021-02-10 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 3 PDB declaration: pentameric
Chain C 158–271（114 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE；3.5 second blot and 3 microlitres sample.
Resolution 2.91 Å
7NHC 1918 H1N1 Viral influenza polymerase heterotrimer - Endonuclease ordered (Class2b) Deposited 2021-02-10 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 3 PDB declaration: pentameric
Chain C 158–271（114 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE；3.5 second blot and 3 microlitres sample.
Resolution 2.87 Å
7NHX 1918 H1N1 Viral influenza polymerase heterotrimer - full transcriptase (Class1) Deposited 2021-02-11 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 3 PDB declaration: pentameric
Chain C 158–271（114 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE；3.5 second blot and 3 microlitres sample.
Resolution 3.23 Å
7NI0 1918 H1N1 Viral influenza polymerase heterotrimer - Replicase (class 3) Deposited 2021-02-11 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 3 PDB declaration: pentameric
Chain C 158–271（114 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE；3.5 second blot and 3 microlitres sample.
Resolution 3.32 Å
7NIK 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8189 core Deposited 2021-02-12 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 4 PDB declaration: hexameric
Chain C 158–271（114 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 6.20 Å
7NIL 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8190 core Deposited 2021-02-12 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 4 PDB declaration: hexameric
Chain C 158–271（114 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 5.01 Å
7NIR 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8191 core Deposited 2021-02-13 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 4 PDB declaration: hexameric
Chain C 158–271（114 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 6.70 Å
7NIS 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8192 core Deposited 2021-02-13 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 4 PDB declaration: hexameric
Chain C 158–271（114 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 5.96 Å
7NJ3 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8196 core Deposited 2021-02-15 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 4 PDB declaration: hexameric
Chain C 158–271（114 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.48 Å
7NJ4 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8198 core Deposited 2021-02-16 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 4 PDB declaration: hexameric
Chain C 158–271（114 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 5.84 Å
7NJ5 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8199 core Deposited 2021-02-16 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 4 PDB declaration: hexameric
Chain C 158–271（114 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.63 Å
7NJ7 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8200 core Deposited 2021-02-16 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 4 PDB declaration: hexameric
Chain C 158–271（114 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.82 Å
7NK1 1918 Influenza virus polymerase heterotirmer in complex with vRNA promoters and Nb8201 Deposited 2021-02-17 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 4 PDB declaration: hexameric
Chain C 158–271（114 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.22 Å
7NK2 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8202 core Deposited 2021-02-17 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 4 PDB declaration: hexameric
Chain C 158–271（114 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.84 Å
8CPL YZw2 a scaffold for cryo-EM of small proteins of interest Deposited 2023-03-03 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Homooligomer；Protein × 4 PDB declaration: tetrameric
Chain A 220–269（50 aa）
Chain B 220–269（50 aa）
Chain C 220–269（50 aa）
Chain D 220–269（50 aa）
Not recorded PLP PYRIDOXAL-5'-PHOSPHATE × 4 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；293 K；16.6% w/v PEG3350, 0.2M NaF and 0.1M Bis-Tris Propane pH 5.5
Resolution 1.60 Å R-free 0.210
8DA3 Coevolved affibody-Z domain pair LL1.c1 Deposited 2022-06-13 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 213–269（57 aa）
Mutation：Q9L, F13I, L17F, G29A, I31F Non-standard monomer：Yes (specific site not provided by mmCIF) SO4 SULFATE ION × 1 MLI MALONATE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 9；295 K；2.4 M Ammonium Sulfate 0.1 M bicine pH 9.0 Cryoprotected with sodium malonate
Resolution 1.06 Å R-free 0.168
8DA4 Coevolved affibody-Z domain pair LL1.c2 Deposited 2022-06-13 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 213–269（57 aa）
Mutation：Q9L, F13I, G29A, I31F Non-standard monomer：Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 4.6；295 K；2.5 M AmmSO4, 0.1 M NaOAc pH 4.6 cryoprotected with Na malonate
Resolution 1.92 Å R-free 0.247
8DA4 Coevolved affibody-Z domain pair LL1.c2 Deposited 2022-06-13 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain C 213–269（57 aa）
Mutation：Q9L, F13I, G29A, I31F Non-standard monomer：Yes (specific site not provided by mmCIF) SO4 SULFATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 4.6；295 K；2.5 M AmmSO4, 0.1 M NaOAc pH 4.6 cryoprotected with Na malonate
Resolution 1.92 Å R-free 0.247
8DA4 Coevolved affibody-Z domain pair LL1.c2 Deposited 2022-06-13 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 3 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain E 213–269（57 aa）
Mutation：Q9L, F13I, G29A, I31F Non-standard monomer：Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 4.6；295 K；2.5 M AmmSO4, 0.1 M NaOAc pH 4.6 cryoprotected with Na malonate
Resolution 1.92 Å R-free 0.247
8DA5 Coevolved affibody-Z domain pair LL1.c4 Deposited 2022-06-13 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 212–269（58 aa）
Mutation：Q9F, F13I, G29A, I31F Non-standard monomer：Yes (specific site not provided by mmCIF) GOL GLYCEROL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 8.5；295 K；2.3 M AmmPO4, 100 mM Tris pH 8.5 cryoprotected with 30% glycerol
Resolution 1.00 Å R-free 0.191
8DA5 Coevolved affibody-Z domain pair LL1.c4 Deposited 2022-06-13 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain C 212–269（58 aa）
Mutation：Q9F, F13I, G29A, I31F Non-standard monomer：Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 8.5；295 K；2.3 M AmmPO4, 100 mM Tris pH 8.5 cryoprotected with 30% glycerol
Resolution 1.00 Å R-free 0.191
8DA6 Coevolved affibody-Z domain pair LL1.c5 Deposited 2022-06-13 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 213–269（57 aa）
Mutation：Q9F, F13I, G29A, I31F Non-standard monomer：Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 5；295 K；2.4 M ammonium Sulfate 0.1 M citric acid pH 5.0 cryoprotected with sodium malonate
Resolution 1.50 Å R-free 0.251
8DA6 Coevolved affibody-Z domain pair LL1.c5 Deposited 2022-06-13 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain C 213–269（57 aa）
Mutation：Q9F, F13I, G29A, I31F No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 5；295 K；2.4 M ammonium Sulfate 0.1 M citric acid pH 5.0 cryoprotected with sodium malonate
Resolution 1.50 Å R-free 0.251
8DA7 Coevolved affibody-Z domain pair LL1.c6 Deposited 2022-06-13 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 213–269（57 aa）
Mutation：Q9L, F13I, G29A, I31F Non-standard monomer：Yes (specific site not provided by mmCIF) MLI MALONATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 8.5；295 K；2.5 M AmmSO4, 100 mM tris pH 8.5 cryoprotected with Na malonate
Resolution 1.02 Å R-free 0.183
8DA8 Coevolved affibody-Z domain pair LL2.c1 Deposited 2022-06-13 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 213–269（57 aa）
Mutation：Q9L F13V, G29A, I31F GOL GLYCEROL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7；295 K；2.5 M ammonium sulfate 100 mM HEPES pH 7.0 Cryoprotected with 30% glycerol
Resolution 1.29 Å R-free 0.235
8DA9 Coevolved affibody-Z domain pair LL2.c3 Deposited 2022-06-13 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 213–269（57 aa）
Mutation：Q9L, F13V, G29A, I31F Non-standard monomer：Yes (specific site not provided by mmCIF) GOL GLYCEROL × 1 SO4 SULFATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7；295 K；2.4 M Ammonium sulfate 0.1M HEPES pH 7.0 Cryoprotected with 30% glycerol
Resolution 1.35 Å R-free 0.198
8DA9 Coevolved affibody-Z domain pair LL2.c3 Deposited 2022-06-13 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain C 213–269（57 aa）
Mutation：Q9L, F13V, G29A, I31F Non-standard monomer：Yes (specific site not provided by mmCIF) GOL GLYCEROL × 1 SO4 SULFATE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7；295 K；2.4 M Ammonium sulfate 0.1M HEPES pH 7.0 Cryoprotected with 30% glycerol
Resolution 1.35 Å R-free 0.198
8DAA Coevolved affibody-Z domain pair LL2.c7 Deposited 2022-06-13 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 213–269（57 aa）
Mutation：Q9L, F13V, G29A, I31F MLI MALONATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7；295 K；3.0 M Ammonium sulfate, 100 mM HEPES pH 7.0 cryoprotected with sodium malonate
Resolution 1.75 Å R-free 0.298
8DAA Coevolved affibody-Z domain pair LL2.c7 Deposited 2022-06-13 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain C 213–269（57 aa）
Mutation：Q9L, F13V, G29A, I31F No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7；295 K；3.0 M Ammonium sulfate, 100 mM HEPES pH 7.0 cryoprotected with sodium malonate
Resolution 1.75 Å R-free 0.298
8DAB Coevolved affibody-Z domain pair LL2.c17 Deposited 2022-06-13 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 213–269（57 aa）
Mutation：Q9V, G29A, I31V Non-standard monomer：Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 8.2；295 K；2.3 M Amm2HPO4, 100 mM Tris pH 8.2 cryoprotected in 30% glycerol
Resolution 1.13 Å R-free 0.200
8DAC Coevolved affibody-Z domain pair LL2.c22 Deposited 2022-06-13 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 213–269（57 aa）
Mutation：Q9I, F13V, L17F, G29A, I31F Non-standard monomer：Yes (specific site not provided by mmCIF) GOL GLYCEROL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 8.2；295 K；2.5 M AmmSO4, 100 mM Tris pH 8.2 Cryoprotected with 30% glycerol
Resolution 1.19 Å R-free 0.196
8JXR Structure of nanobody-bound DRD1_LSD complex Deposited 2023-07-01 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 5 PDB declaration: pentameric
Chain C 289–327（39 aa）
Mutation：E360Q,K363A,D364F,T367I,R368L 7LD (8alpha)-N,N-diethyl-6-methyl-9,10-didehydroergoline-8-carboxamide × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.57 Å
8JXS Structure of nanobody-bound DRD1_PF-6142 complex Deposited 2023-07-01 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 5 PDB declaration: pentameric
Chain C 289–327（39 aa）
Mutation：E360Q,K363A,D364F,T367I,R368L,D404E,A405H V6X 4-[3-methyl-4-(6-methylimidazo[1,2-a]pyrazin-5-yl)phenoxy]furo[3,2-c]pyridine × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.00 Å
8R2P YZwIdeal x16 a scaffold for cryo-EM of small proteins of interest crystallizing in space group 19 (P 21 21 21) Deposited 2023-11-07 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Homooligomer；Protein × 4 PDB declaration: tetrameric
Chain A 218–269（52 aa）
Chain B 218–269（52 aa）
Chain C 218–269（52 aa）
Chain D 218–269（52 aa）
Mutation：G487A Mutation：G487A Mutation：G487A Mutation：G487A PLP PYRIDOXAL-5'-PHOSPHATE × 4 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.5；277 K；50% w/v PEG200, 0.2M MgCl2 and 0.1M Sodium Cacodylate buffer pH 6.5
Resolution 2.22 Å R-free 0.230
9QU4 Cryo-EM structure of the inward-open choline-bound state of choline/ethanolamine transporter FLVCR2 Deposited 2025-04-10 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Monomer；Protein × 1 PDB declaration: monomeric
Chain A 159–321（163 aa）
Not recorded CHT CHOLINE ION × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.39 Å
9W3K GPR151-Legobody complex Deposited 2025-07-29 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 5 PDB declaration: pentameric
Chain C 289–327（39 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.08 Å

66 other PDB entries and 127 assemblies. Open the comparison page and filter oligomeric states

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UniProt name SPA_STAAU
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 452–501； UniProt 220–269

Putrescine aminotransferase,Immunoglobulin G-binding protein A

Staphylococcus aureus

UniProt P42588

State in the Current Structure

Assembly Oligomeric State Construct Mutations and Modifications Ligands, Ions and Associated Components Method and Experimental Conditions Structure Quality
1 Insufficient information Heteromer Protein × 8 PDB declaration: octameric（8） Consistent with protein copy count Chain A； UniProt 7–453 Fragment：UNP RESIDUES 7-453,220-269 Mutation：N222V, G240A Zpa963,cAMP-dependent protein kinase catalytic subunit alpha × 4 （P05132） X-RAY DIFFRACTION X-ray crystallization conditions：VAPOR DIFFUSION；pH 5.5；296 K；91mM MES pH 5.5, 2.33M Na formate Resolution 3.38 Å R-free 0.227

Other States of the Same Protein in the Database

Each row is a biological assembly of the same UniProt protein in another PDB entry. The “Difference from current entry” column identifies evidence-level differences; no tag means the currently parsed fields agree.

Other PDB Difference from Current Entry 5X3F Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Method and Experimental Conditions Structure Quality
4UOX Crystal structure of YgjG in complex with Pyridoxal-5'-phosphate and putrescine Deposited 2014-06-11 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric
Chain A 1–459（459 aa）
Chain B 1–459（459 aa）
Chain C 1–459（459 aa）
Chain D 1–459（459 aa）
Not recorded PLP PYRIDOXAL-5'-PHOSPHATE × 4 PUT 1,4-DIAMINOBUTANE × 3 FMT FORMIC ACID × 6 GOL GLYCEROL × 3 PEG DI(HYDROXYETHYL)ETHER × 1 X-RAY DIFFRACTION
X-ray crystallization conditions pH 7.5；0.1 M HEPES PH 7.5, 15% PEG 3350, 0.2 M SODIUM FORMATE, 0.1 MM N-DODECYL-N,N-DIMETHYLGLYCINE
Resolution 2.08 Å R-free 0.245
4UOY Crystal structure of YgjG in complex with Pyridoxal-5'-phosphate Deposited 2014-06-11 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric
Chain A 1–459（459 aa）
Chain B 1–459（459 aa）
Chain C 1–459（459 aa）
Chain D 1–459（459 aa）
Not recorded PLP PYRIDOXAL-5'-PHOSPHATE × 4 FMT FORMIC ACID × 1 GOL GLYCEROL × 2 X-RAY DIFFRACTION
X-ray crystallization conditions pH 7.5；0.1 M HEPES PH 7.5 15% PEG 3350 0.2 M SODIUM FORMATE 0.1 MM N-DODECYL-N,N-DIMETHYLGLYCINE
Resolution 2.31 Å R-free 0.233
5H7D Crystal structure of the YgjG-protein A-Zpa963-calmodulin complex Deposited 2016-11-17 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 8 PDB declaration: octameric
Chain A 7–453（447 aa） Fragment：UNP RESIDUES 7-453,UNP RESIDUES 220-267
Chain B 7–453（447 aa） Fragment：UNP RESIDUES 7-453,UNP RESIDUES 220-267
Chain C 7–453（447 aa） Fragment：UNP RESIDUES 7-453,UNP RESIDUES 220-267
Chain D 7–453（447 aa） Fragment：UNP RESIDUES 7-453,UNP RESIDUES 220-267
Mutation：N222V, G240A Mutation：N222V, G240A Mutation：N222V, G240A Mutation：N222V, G240A CA CALCIUM ION × 8 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 7.5；296 K；0.1M HEPES pH 7.5, 20.7% PEG 300, 99mM calcium chloride
Resolution 2.57 Å R-free 0.241
5H7D Crystal structure of the YgjG-protein A-Zpa963-calmodulin complex Deposited 2016-11-17 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Insufficient information Heteromer；Protein × 8 PDB declaration: octameric
Chain I 7–453（447 aa） Fragment：UNP RESIDUES 7-453,UNP RESIDUES 220-267
Chain J 7–453（447 aa） Fragment：UNP RESIDUES 7-453,UNP RESIDUES 220-267
Chain M 7–453（447 aa） Fragment：UNP RESIDUES 7-453,UNP RESIDUES 220-267
Chain N 7–453（447 aa） Fragment：UNP RESIDUES 7-453,UNP RESIDUES 220-267
Mutation：N222V, G240A Mutation：N222V, G240A Mutation：N222V, G240A Mutation：N222V, G240A CA CALCIUM ION × 8 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 7.5；296 K；0.1M HEPES pH 7.5, 20.7% PEG 300, 99mM calcium chloride
Resolution 2.57 Å R-free 0.241
8CPL YZw2 a scaffold for cryo-EM of small proteins of interest Deposited 2023-03-03 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Homooligomer；Protein × 4 PDB declaration: tetrameric
Chain A 7–457（451 aa）
Chain B 7–457（451 aa）
Chain C 7–457（451 aa）
Chain D 7–457（451 aa）
Not recorded PLP PYRIDOXAL-5'-PHOSPHATE × 4 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；293 K；16.6% w/v PEG3350, 0.2M NaF and 0.1M Bis-Tris Propane pH 5.5
Resolution 1.60 Å R-free 0.210
8R2P YZwIdeal x16 a scaffold for cryo-EM of small proteins of interest crystallizing in space group 19 (P 21 21 21) Deposited 2023-11-07 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Homooligomer；Protein × 4 PDB declaration: tetrameric
Chain A 7–457（451 aa）
Chain B 7–457（451 aa）
Chain C 7–457（451 aa）
Chain D 7–457（451 aa）
Mutation：G487A Mutation：G487A Mutation：G487A Mutation：G487A PLP PYRIDOXAL-5'-PHOSPHATE × 4 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.5；277 K；50% w/v PEG200, 0.2M MgCl2 and 0.1M Sodium Cacodylate buffer pH 6.5
Resolution 2.22 Å R-free 0.230

5 other PDB entries and 6 assemblies. Open the comparison page and filter oligomeric states

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UniProt name PAT_ECOLI
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 5–451； UniProt 7–453

Zpa963,cAMP-dependent protein kinase catalytic subunit alpha

Mus musculus

UniProt P05132

State in the Current Structure

Assembly Oligomeric State Construct Mutations and Modifications Ligands, Ions and Associated Components Method and Experimental Conditions Structure Quality
1 Insufficient information Heteromer Protein × 8 PDB declaration: octameric（8） Consistent with protein copy count Chain B； UniProt 19–351 Fragment：residues 97-156,UNP RESIDUES 11-343 Non-standard monomer：Yes (specific site not provided by mmCIF) Putrescine aminotransferase,Immunoglobulin G-binding protein A × 4 （P42588,P38507） X-RAY DIFFRACTION X-ray crystallization conditions：VAPOR DIFFUSION；pH 5.5；296 K；91mM MES pH 5.5, 2.33M Na formate Resolution 3.38 Å R-free 0.227

Other States of the Same Protein in the Database

Each row is a biological assembly of the same UniProt protein in another PDB entry. The “Difference from current entry” column identifies evidence-level differences; no tag means the currently parsed fields agree.

Other PDB Difference from Current Entry 5X3F Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Method and Experimental Conditions Structure Quality
1APM 2.0 ANGSTROM REFINED CRYSTAL STRUCTURE OF THE CATALYTIC SUBUNIT OF CAMP-DEPENDENT PROTEIN KINASE COMPLEXED WITH A PEPTIDE INHIBITOR AND DETERGENT Deposited 1993-01-18 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain E 1–350（350 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) OCT N-OCTANE × 1 X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 2.00 Å
1ATP 2.2 angstrom refined crystal structure of the catalytic subunit of cAMP-dependent protein kinase complexed with MNATP and a peptide inhibitor Deposited 1993-01-08 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain E 1–350（350 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) MN MANGANESE (II) ION × 2 ATP ADENOSINE-5'-TRIPHOSPHATE × 1 X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 2.20 Å
1BKX A BINARY COMPLEX OF THE CATALYTIC SUBUNIT OF CAMP-DEPENDENT PROTEIN KINASE AND ADENOSINE FURTHER DEFINES CONFORMATIONAL FLEXIBILITY Deposited 1997-07-01 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 1–350（350 aa） Fragment：CATALYTIC SUBUNIT
Non-standard monomer：Yes (specific site not provided by mmCIF) AMP ADENOSINE MONOPHOSPHATE × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8；277 K；THE RC.ADE BINARY COMPLEX CRYSTALS WERE GROWN AT 4 C BY THE HANGING-DROP VAPOR DIFFUSION METHOD. THE CRYSTALLIZATION DROPLET CONTAINED PROTEIN (0.5 MM), ADENOSINE (3 MM) AND 2-METHYL-2,4-PENTANEDIOL (MPD; 4%) IN 100 MM BICINE BUFFER AT PH 8.0. THE CRYSTALLIZATION WELL SOLUTION WAS MADE UP OF 15% MPD AND 100 MM AMMONIUM-SULFATE IN BICINE BUFFER (100 MM; PH 8.0). THE CRYSTALS GREW OVER THE COURSE OF 8-12 WEEKS TO A FINAL SIZE OF 0.2 X 0.3 X 0.5 MM3., vapor diffusion - hanging drop, temperature 277K
Resolution 2.60 Å R-free 0.340
1BX6 CRYSTAL STRUCTURE OF THE POTENT NATURAL PRODUCT INHIBITOR BALANOL IN COMPLEX WITH THE CATALYTIC SUBUNIT OF CAMP-DEPENDENT PROTEIN KINASE Deposited 1998-10-13 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 1–350（350 aa） Fragment：CATALYTIC DOMAIN
Non-standard monomer：Yes (specific site not provided by mmCIF) BA1 BALANOL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions pH 8；pH 8.0
Resolution 2.10 Å R-free 0.340
1FMO CRYSTAL STRUCTURE OF A POLYHISTIDINE-TAGGED RECOMBINANT CATALYTIC SUBUNIT OF CAMP-DEPENDENT PROTEIN KINASE COMPLEXED WITH THE PEPTIDE INHIBITOR PKI(5-24) AND ADENOSINE Deposited 1997-07-08 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain E 1–350（350 aa） Fragment：CATALYTIC SUBUNIT
Non-standard monomer：Yes (specific site not provided by mmCIF) ADN ADENOSINE × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8；277 K；ORTHORHOMBIC CRYSTALS OF THE TERNARY COMPLEX, COMPRISED OF MOUSE HIS6-RC SUBUNIT, PKI (5-24) AND ADENOSINE, WERE GROWN BY THE HANGING-DROP VAPOUR DIFFUSION METHOD USING 2-METHYL-2,4-PENTANEDIOL (MPD) AS THE PRECIPITATING AGENT. THE MOTHER-LIQUOR CONTAINED PROTEIN AT A CONCENTRATION OF 0.25 MM IN 100 MM BICINE BUFFER AT PH 8.0, 0.75 MM PKI(5-24), 4 MM ADENOSINE AND 4% MPD. THE RESERVOIR SOLUTION WAS MADE UP OF 20% MPD IN 100 MM BICINE BUFFER (PH 8.0). X-RAY DIFFRACTION QUALITY CRYSTALS (0.2 X 0.15 X 0.8 MM3) WERE GROWN AT 4 C IN APPROXIMATELY 4 - 6 WEEKS., vapor diffusion - hanging drop, temperature 277K
Resolution 2.20 Å
1J3H Crystal structure of apoenzyme cAMP-dependent protein kinase catalytic subunit Deposited 2003-01-31 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 1–350（350 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) MPD (4S)-2-METHYL-2,4-PENTANEDIOL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8；277 K；Tris-hydrogen chloride, MPD, Bicine, ammonium acetate, pH 8.0, VAPOR DIFFUSION, HANGING DROP, temperature 277K
Resolution 2.90 Å R-free 0.291
1J3H Crystal structure of apoenzyme cAMP-dependent protein kinase catalytic subunit Deposited 2003-01-31 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain B 1–350（350 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) MPD (4S)-2-METHYL-2,4-PENTANEDIOL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8；277 K；Tris-hydrogen chloride, MPD, Bicine, ammonium acetate, pH 8.0, VAPOR DIFFUSION, HANGING DROP, temperature 277K
Resolution 2.90 Å R-free 0.291
1JBP Crystal Structure of the Catalytic Subunit of cAMP-dependent Protein Kinase Complexed with a Substrate Peptide, ADP and Detergent Deposited 2001-06-06 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain E 1–350（350 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) ADP ADENOSINE-5'-DIPHOSPHATE × 1 OCT N-OCTANE × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8；277 K；Vapor diffusion,hanging drop,pH 8.0,277K, 10mM dithiothreitol, 8% Dow polyethylene glycol 400,methanol, Bicine, VAPOR DIFFUSION, HANGING DROP
Resolution 2.20 Å
1JLU Crystal Structure of the Catalytic Subunit of cAMP-dependent Protein Kinase Complexed with a Phosphorylated Substrate Peptide and Detergent Deposited 2001-07-16 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain E 1–350（350 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) OCT N-OCTANE × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8；277 K；Vapor diffusion, hanging drop, pH 8.0,277K, 10mM dithiothreitol, 8% Dow polyethylene glycol 400, methanol, Bicine, VAPOR DIFFUSION, HANGING DROP
Resolution 2.25 Å
1L3R Crystal Structure of a Transition State Mimic of the Catalytic Subunit of cAMP-dependent Protein Kinase Deposited 2002-02-28 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain E 1–350（350 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) MG MAGNESIUM ION × 2 ADP ADENOSINE-5'-DIPHOSPHATE × 1 AF3 ALUMINUM FLUORIDE × 1 MPD (4S)-2-METHYL-2,4-PENTANEDIOL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8；277 K；MPD, bicine, methanol, ammonium acetate, pH 8.0, VAPOR DIFFUSION, HANGING DROP, temperature 277K
Resolution 2.00 Å R-free 0.232
1RDQ Hydrolysis of ATP in the crystal of Y204A mutant of cAMP-dependent protein kinase Deposited 2003-11-05 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain E 1–350（350 aa）
Mutation：Y204A Non-standard monomer：Yes (specific site not provided by mmCIF) PO4 PHOSPHATE ION × 1 MG MAGNESIUM ION × 2 ADP ADENOSINE-5'-DIPHOSPHATE × 1 ATP ADENOSINE-5'-TRIPHOSPHATE × 1 MRD (4R)-2-METHYLPENTANE-2,4-DIOL × 1 GOL GLYCEROL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8；277 K；MPD, Bicine, ammonium acetate, pH 8.0, VAPOR DIFFUSION, HANGING DROP, temperature 277.0K
Resolution 1.26 Å R-free 0.162
1RE8 Crystal structure of cAMP-dependent protein kinase complexed with balanol analog 2 Deposited 2003-11-06 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 1–350（350 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) BD2 3-[(4-HYDROXYBENZOYL)AMINO]AZEPAN-4-YL 4-(2-HYDROXYBENZOYL)BENZOATE × 1 OCT N-OCTANE × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8；277.15 K；MPD, Bicine, Mega-9, pH 8, VAPOR DIFFUSION, HANGING DROP, temperature 277.15K
Resolution 2.10 Å R-free 0.252
1REJ Crystal structure of cAMP-dependent protein kinase complexed with balanol analog 1 Deposited 2003-11-06 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 1–350（350 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) B1L 3-[(4-HYDROXYBENZOYL)AMINO]AZEPAN-4-YL 4-HYDROXYBENZOATE × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8；277.15 K；MPD, Bicine, Tris-HCl, pH 8, VAPOR DIFFUSION, HANGING DROP, temperature 277.15K
Resolution 2.20 Å R-free 0.291
1REK Crystal structure of cAMP-dependent protein kinase complexed with balanol analog 8 Deposited 2003-11-06 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 1–350（350 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) B8L 3-[(3-SEC-BUTYL-4-HYDROXYBENZOYL)AMINO]AZEPAN-4-YL 4-(2-HYDROXY-5-METHOXYBENZOYL)BENZOATE × 1 PTL PENTANAL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8；277.15 K；MPD, Bicine, Mega-8, Tris-HCl, VAPOR DIFFUSION, HANGING DROP, temperature 277.15K
Resolution 2.30 Å R-free 0.295
1SYK Crystal structure of E230Q mutant of cAMP-dependent protein kinase reveals unexpected apoenzyme conformation Deposited 2004-04-01 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 1–350（350 aa）
Mutation：E230Q Non-standard monomer：Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8；277 K；MPD, MeOH, pH 8.0, VAPOR DIFFUSION, HANGING DROP, temperature 277.0K
Resolution 2.80 Å R-free 0.249
1SYK Crystal structure of E230Q mutant of cAMP-dependent protein kinase reveals unexpected apoenzyme conformation Deposited 2004-04-01 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain B 1–350（350 aa）
Mutation：E230Q Non-standard monomer：Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8；277 K；MPD, MeOH, pH 8.0, VAPOR DIFFUSION, HANGING DROP, temperature 277.0K
Resolution 2.80 Å R-free 0.249
2CPK CRYSTAL STRUCTURE OF THE CATALYTIC SUBUNIT OF CYCLIC ADENOSINE MONOPHOSPHATE-DEPENDENT PROTEIN KINASE Deposited 1992-10-21 Different construct Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain E 1–350（350 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 2.70 Å
2ERZ Crystal Structure of c-AMP Dependent Kinase (PKA) bound to hydroxyfasudil Deposited 2005-10-25 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain E 0–350（351 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) HFS 1-(1-HYDROXY-5-ISOQUINOLINESULFONYL)HOMOPIPERAZINE × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7；277 K；bicine, pH 7.0, 2% MPD, VAPOR DIFFUSION, HANGING DROP, temperature 277K
Resolution 2.20 Å R-free 0.287
2QCS A complex structure between the Catalytic and Regulatory subunit of Protein Kinase A that represents the inhibited state Deposited 2007-06-19 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 2–351（350 aa） Fragment：CATALYTIC SUBUNIT
Non-standard monomer：Yes (specific site not provided by mmCIF) MN MANGANESE (II) ION × 2 SO4 SULFATE ION × 6 ACT ACETATE ION × 1 ANP PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER × 1 TAM TRIS(HYDROXYETHYL)AMINOMETHANE × 1 GOL GLYCEROL × 3 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 5.5；298 K；2.0M(NH4)2SO4, 0.1M Citrate, pH 5.5, VAPOR DIFFUSION, SITTING DROP, temperature 298K
Resolution 2.20 Å R-free 0.225
2QUR Crystal Structure of F327A/K285P Mutant of cAMP-dependent Protein Kinase Deposited 2007-08-06 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 2–351（350 aa）
Mutation：K285P/F327A Non-standard monomer：Yes (specific site not provided by mmCIF) ADP ADENOSINE-5'-DIPHOSPHATE × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.5；277 K；8-12% MPD, 100 mM Tris-HCl, plus 10 mM DTT, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 277K
Resolution 2.50 Å R-free 0.265
2QVS Crystal Structure of Type IIa Holoenzyme of cAMP-dependent Protein Kinase Deposited 2007-08-08 Different construct Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain E 2–351（350 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.5；295.5 K；1.9 M sodium formate, pH 5.5, VAPOR DIFFUSION, HANGING DROP, temperature 295.5K
Resolution 2.50 Å R-free 0.251
3FHI Crystal structure of a complex between the catalytic and regulatory (RI{alpha}) subunits of PKA Deposited 2008-12-09 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 2–351（350 aa）
Mutation：C199A Non-standard monomer：Yes (specific site not provided by mmCIF) ANP PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER × 1 MN MANGANESE (II) ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7；298 K；20 % PEG 2000, 0.1 M Tris-HCl, 4 % 1,3-Propanediol, 2.0 mM Cyclohexyl-pentyl-D-maltoside, pH 7.0, VAPOR DIFFUSION, HANGING DROP, temperature 298K
Resolution 2.00 Å R-free 0.226
3FJQ Crystal structure of cAMP-dependent protein kinase catalytic subunit alpha in complex with peptide inhibitor PKI alpha (6-25) Deposited 2008-12-15 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain E 2–351（350 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) MN MANGANESE (II) ION × 2 ATP ADENOSINE-5'-TRIPHOSPHATE × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.5；278 K；Protein solution: 10mM MOPS buffer pH 7.0, 50 mM NaCl, 3mM MnCl2, 0.2 mM ATP. Well solution: 0.5 M (NH4)2SO4, 0.1 M HEPES, 10 % MPD, VAPOR DIFFUSION, HANGING DROP, temperature 278K
Resolution 1.60 Å R-free 0.205
3IDB Crystal structure of (108-268)RIIb:C holoenzyme of cAMP-dependent protein kinase Deposited 2009-07-20 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 2–351（350 aa） Fragment：Isoform 1 (C-alpha-1): UNP residues 2-351
Non-standard monomer：Yes (specific site not provided by mmCIF) MN MANGANESE (II) ION × 2 ANP PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION UNDER OIL (VDUO)；pH 7.5；298 K；8% PEG 3350, 40 mM Bis-Tris pH 7.5, 0.05 mM Na Acetate, VAPOR DIFFUSION UNDER OIL (VDUO), temperature 298.0K
Resolution 1.62 Å R-free 0.230
3IDC Crystal structure of (102-265)RIIb:C holoenzyme of cAMP-dependent protein kinase Deposited 2009-07-20 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 2–351（350 aa） Fragment：Isoform 1 (C-alpha-1): UNP residues 2-351
Non-standard monomer：Yes (specific site not provided by mmCIF) MN MANGANESE (II) ION × 2 ANP PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION UNDER OIL (VDUO)；pH 7.5；298 K；8% PEG 3350, 40 mM Bis-Tris pH 7.5, 0.05 mM Na Acetate, VAPOR DIFFUSION UNDER OIL (VDUO), temperature 298K
Resolution 2.70 Å R-free 0.319
3J4Q Pseudo-atomic model of the AKAP18-PKA complex in a bent conformation derived from electron microscopy Deposited 2013-09-25 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 5 PDB declaration: pentameric
Chain D 1–351（351 aa）
Chain E 1–351（351 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer 25 mM HEPES, pH 7.4, 200 mM NaCl, 0.5 mM EDTA, 1 mM DTT；pH 7.4；25 mM HEPES, pH 7.4, 200 mM NaCl, 0.5 mM EDTA, 1 mM DTT
Resolution 35.00 Å
3J4R Pseudo-atomic model of the AKAP18-PKA Complex in a linear conformation derived from electron microscopy Deposited 2013-09-25 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 5 PDB declaration: pentameric
Chain D 1–351（351 aa）
Chain E 1–351（351 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer 25 mM HEPES, pH 7.4, 200 mM NaCl, 0.5 mM EDTA, 1 mM DTT；pH 7.4；25 mM HEPES, pH 7.4, 200 mM NaCl, 0.5 mM EDTA, 1 mM DTT
Resolution 35.00 Å
3O7L Crystal Structure of phospholamban (1-19):PKA C-subunit:AMP-PNP:Mg2+ complex Deposited 2010-07-30 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric
Chain B 2–351（350 aa） Fragment：phospholamban peptide
Chain D 2–351（350 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) MG MAGNESIUM ION × 2 PEG DI(HYDROXYETHYL)ETHER × 1 ANP PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.5；298 K；The complex was obtained by combining a 1:10:10:10 molar ratio mixture of PKA-C (7 mg/ml), PLN1-19, MgCl2, and AMP-PNP in 20 mM sodium acetate (pH 6.5), 180 mM KCl, and 5 mM DTT, VAPOR DIFFUSION, HANGING DROP, temperature 298.0K
Resolution 2.80 Å R-free 0.287
3OW3 Discovery of dihydrothieno- and dihydrofuropyrimidines as potent pan Akt inhibitors Deposited 2010-09-17 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 2–351（350 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) SMY (2R)-3-(1H-indol-3-yl)-1-{4-[(5S)-5-methyl-5,7-dihydrothieno[3,4-d]pyrimidin-4-yl]piperazin-1-yl}-1-oxopropan-2-amine × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8；277 K；6.6mg/ml PKA with 0.25mM PKI, 50mM bicine, 150mM ammonium acetate, 2mM DTT, 8% PEG400, 11% methanol, pH 8.0, VAPOR DIFFUSION, HANGING DROP, temperature 277K
Resolution 1.90 Å R-free 0.210
3PVB Crystal structure of (73-244)RIa:C holoenzyme of cAMP-dependent Protein kinase Deposited 2010-12-06 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 7–351（345 aa） Fragment：unp residues 7-351
Non-standard monomer：Yes (specific site not provided by mmCIF) ANP PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER × 1 MN MANGANESE (II) ION × 2 GOL GLYCEROL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6；298 K；The RIa(73-244):C complex was crystallized in 0.1M MES pH 6.0 and 12% PEG 20,000 by using a Douglas Instruments Oryx8 crystallography robot as 1:1 protein solution:crystallizing solution, VAPOR DIFFUSION, SITTING DROP, temperature 298.0 K
Resolution 3.30 Å R-free 0.290
3QAL Crystal Structure of Arg280Ala mutant of Catalytic subunit of cAMP-dependent Protein Kinase Deposited 2011-01-11 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain E 2–351（350 aa）
Mutation：E208A Non-standard monomer：Yes (specific site not provided by mmCIF) ATP ADENOSINE-5'-TRIPHOSPHATE × 1 MG MAGNESIUM ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8；277 K；13-15% MPD, 100 mM Bicine, 10 mM DTT, pH 8.0, VAPOR DIFFUSION, HANGING DROP, temperature 277K
Resolution 1.70 Å R-free 0.194
3QAM Crystal Structure of Glu208Ala mutant of catalytic subunit of cAMP-dependent protein kinase Deposited 2011-01-11 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain E 2–351（350 aa）
Mutation：E208A Non-standard monomer：Yes (specific site not provided by mmCIF) ATP ADENOSINE-5'-TRIPHOSPHATE × 1 MG MAGNESIUM ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.5；277 K；10-12% polyethylene glycol 6000, 100 mM Tris-HCl, 10 mM DTT, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 277K
Resolution 1.92 Å R-free 0.228
3TNP Structure and Allostery of the PKA RIIb Tetrameric Holoenzyme Deposited 2011-09-01 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric
Chain C 2–351（350 aa）
Chain F 2–351（350 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.5；298 K；The RII (R230K)2:C2 holoenzyme complex was crystallized at room temperature in 10% PEG8000, 8% ethylene glycol, pH7.5 HEPES buffer by using vapor diffusion at a 1:1 ratio of protein to crystallization solution. VAPOR DIFFUSION, HANGING DROP, temperature 298K
Resolution 2.30 Å R-free 0.235
3TNP Structure and Allostery of the PKA RIIb Tetrameric Holoenzyme Deposited 2011-09-01 Different construct Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain C 2–351（350 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.5；298 K；The RII (R230K)2:C2 holoenzyme complex was crystallized at room temperature in 10% PEG8000, 8% ethylene glycol, pH7.5 HEPES buffer by using vapor diffusion at a 1:1 ratio of protein to crystallization solution. VAPOR DIFFUSION, HANGING DROP, temperature 298K
Resolution 2.30 Å R-free 0.235
3TNP Structure and Allostery of the PKA RIIb Tetrameric Holoenzyme Deposited 2011-09-01 Different construct Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 3 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain F 2–351（350 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.5；298 K；The RII (R230K)2:C2 holoenzyme complex was crystallized at room temperature in 10% PEG8000, 8% ethylene glycol, pH7.5 HEPES buffer by using vapor diffusion at a 1:1 ratio of protein to crystallization solution. VAPOR DIFFUSION, HANGING DROP, temperature 298K
Resolution 2.30 Å R-free 0.235
3X2U Michaelis-like initial complex of cAMP-dependent Protein Kinase Catalytic Subunit. Deposited 2015-01-02 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 1–351（351 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) ATP ADENOSINE-5'-TRIPHOSPHATE × 1 MG MAGNESIUM ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.5；277 K；100mM MES pH 6.5, 5mM DTT, 15-20% PEG 3350, VAPOR DIFFUSION, SITTING DROP, temperature 277K
Resolution 2.40 Å R-free 0.239
3X2V Michaelis-like complex of cAMP-dependent Protein Kinase Catalytic Subunit Deposited 2015-01-02 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 1–351（351 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) MG MAGNESIUM ION × 2 ATP ADENOSINE-5'-TRIPHOSPHATE × 1 CO3 CARBONATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.5；277 K；100mM MES pH 6.5, 5mM DTT, 15-20% PEG 3350, VAPOR DIFFUSION, SITTING DROP, temperature 277K
Resolution 1.77 Å R-free 0.230
3X2W Michaelis complex of cAMP-dependent Protein Kinase Catalytic Subunit Deposited 2015-01-02 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 1–351（351 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) MG MAGNESIUM ION × 2 ATP ADENOSINE-5'-TRIPHOSPHATE × 1 CO3 CARBONATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.5；277 K；100mM MES pH 6.5, 5mM DTT, 15-20% PEG 3350, VAPOR DIFFUSION, SITTING DROP, temperature 277K
Resolution 1.70 Å R-free 0.198
4DFX Crystal structure of myristoylated K7C catalytic subunit of cAMP-dependent protein kinase in complex with SP20 and AMP-PNP Deposited 2012-01-24 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain E 2–351（350 aa） Fragment：UNP RESIDUES 2-351
Mutation：K7C Non-standard monomer：Yes (specific site not provided by mmCIF) MYR MYRISTIC ACID × 1 ANP PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER × 1 MG MAGNESIUM ION × 2 GOL GLYCEROL × 3 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8；277.15 K；Mother liquor: 12% MPD, 100 mM Bis-Tris, Protein solution: 50 mM Bicine, 150 mM Ammonium Acetate, 10 mM DTT, 8-10 mg/mL 9% MeOH added to the well immediately before sealing. 8 uL drop size with 1:1 protein:mother liquor, VAPOR DIFFUSION, HANGING DROP, temperature 277.15K, pH 8.0
Resolution 1.35 Å R-free 0.179
4DFY Crystal structure of R194A mutant of cAMP-dependent protein kinase with unphosphorylated activation loop Deposited 2012-01-24 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 1–351（351 aa）
Mutation：R194A Non-standard monomer：Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.5；277.15 K；100 mM Tris, 800 mM sodium formate, 10% PEG 8000, 10% PEG 1000, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 277.15K
Resolution 3.00 Å R-free 0.286
4DFY Crystal structure of R194A mutant of cAMP-dependent protein kinase with unphosphorylated activation loop Deposited 2012-01-24 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain E 1–351（351 aa）
Mutation：R194A Non-standard monomer：Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.5；277.15 K；100 mM Tris, 800 mM sodium formate, 10% PEG 8000, 10% PEG 1000, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 277.15K
Resolution 3.00 Å R-free 0.286
4DFY Crystal structure of R194A mutant of cAMP-dependent protein kinase with unphosphorylated activation loop Deposited 2012-01-24 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 3 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric
Chain A 1–351（351 aa）
Chain E 1–351（351 aa）
Mutation：R194A Non-standard monomer：Yes (specific site not provided by mmCIF) Mutation：R194A Non-standard monomer：Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.5；277.15 K；100 mM Tris, 800 mM sodium formate, 10% PEG 8000, 10% PEG 1000, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 277.15K
Resolution 3.00 Å R-free 0.286
4DFY Crystal structure of R194A mutant of cAMP-dependent protein kinase with unphosphorylated activation loop Deposited 2012-01-24 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 4 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 1–351（351 aa）
Chain E 1–351（351 aa）
Mutation：R194A Non-standard monomer：Yes (specific site not provided by mmCIF) Mutation：R194A Non-standard monomer：Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.5；277.15 K；100 mM Tris, 800 mM sodium formate, 10% PEG 8000, 10% PEG 1000, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 277.15K
Resolution 3.00 Å R-free 0.286
4DFZ Crystal structure of myristoylated K7C catalytic subunit of cAMP-dependent protein kinase in complex with SP20 Deposited 2012-01-24 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain E 2–351（350 aa） Fragment：unp residues 2-351
Mutation：K7C Non-standard monomer：Yes (specific site not provided by mmCIF) MYR MYRISTIC ACID × 1 X-RAY DIFFRACTION
X-ray crystallization conditions pH 8；277.15 K；Mother liquor: 6% MPD Protein: 50 mM Bicine, 150 mM Ammonium acetate, 10 mM DTT, 8-10 mg/mL protein, 9% MeOH added to well immediately before sealing, VAPOR DIFFUSION, HANGING DROP, temperature 277.15K, pH 8.0
Resolution 2.00 Å R-free 0.234
4DG0 Crystal structure of myristoylated WT catalytic subunit of cAMP-dependent protein kinase in complex with SP20 and AMP-PNP Deposited 2012-01-24 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain E 2–351（350 aa） Fragment：unp residues 2-351
Non-standard monomer：Yes (specific site not provided by mmCIF) MYR MYRISTIC ACID × 1 ANP PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER × 1 MG MAGNESIUM ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions pH 8；277.15 K；Mother liquor: 10% MPD Protein solution: 50 mM Bicine, 150 mM Ammonium Acetate, 8-10 mg/mL 9% MeOH added to the well immediately before sealing. 8 uL drop size with 1:1 protein:mother liquor, VAPOR DIFFUSION, HANGING DROP, temperature 277.15K, pH 8.0
Resolution 2.00 Å R-free 0.228
4DG2 Crystal structure of myristoylated WT catalytic subunit of cAMP-dependent protein kinase in complex with SP20 Deposited 2012-01-24 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain E 2–351（350 aa） Fragment：UNP RESIDUES 2-351
Non-standard monomer：Yes (specific site not provided by mmCIF) MYR MYRISTIC ACID × 1 X-RAY DIFFRACTION
X-ray crystallization conditions pH 8；277.15 K；Mother liquor: 6% MPD Protein solution: 50 mM Bicine, 150 mM Ammonium Acetate, 10 mM DTT, 8-10 mg/mL 9% MeOH, 1:1 protein:mother liquor, VAPOR DIFFUSION, HANGING DROP, temperature 277.15K, pH 8.0
Resolution 2.00 Å R-free 0.211
4DG3 Crystal structure of R336A mutant of cAMP-dependent protein kinase with unphosphorylated turn motif. Deposited 2012-01-24 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain E 1–351（351 aa）
Mutation：R336A Non-standard monomer：Yes (specific site not provided by mmCIF) ANP PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER × 1 MG MAGNESIUM ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8；277.15 K；8-14% MPD, 100 mM Tris, 10 mM DTT. 11-13% methanol added to well before sealing, pH 8.0, VAPOR DIFFUSION, HANGING DROP, temperature 277.15K
Resolution 1.80 Å R-free 0.217
4DH1 Low temperature X-ray structure of cAMP dependent Protein Kinase A catalytic subunit with low Mg2+, ATP and IP20 Deposited 2012-01-27 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 16–351（336 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) MG MAGNESIUM ION × 1 ATP ADENOSINE-5'-TRIPHOSPHATE × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.5；277 K；50 mM MES (pH=6.5), 5 mM DTT and 12-15% PEG4000, VAPOR DIFFUSION, SITTING DROP, temperature 277K
Resolution 2.00 Å R-free 0.234
4DH3 Low temperature X-ray structure of cAMP dependent Protein Kinase A catalytic subunit with high Mg2+, ATP and IP20 Deposited 2012-01-27 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 2–351（350 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) MG MAGNESIUM ION × 2 ATP ADENOSINE-5'-TRIPHOSPHATE × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.5；277 K；50 mM MES (pH=6.5), 50 mM Mg2Cl, 5 mM DTT and 12-15% PEG4000, VAPOR DIFFUSION, SITTING DROP, temperature 277K
Resolution 2.20 Å R-free 0.233
4DH5 Room temperature X-ray structure of cAMP dependent Protein Kinase A catalytic subunit with high Mg2+, ADP, Phosphate, and IP20 Deposited 2012-01-27 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 2–351（350 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) MG MAGNESIUM ION × 2 ADP ADENOSINE-5'-DIPHOSPHATE × 1 PO4 PHOSPHATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.5；277 K；50 mM MES (pH=6.5), 50 mM Mg2Cl, 5 mM DTT and 12-15% PEG4000, VAPOR DIFFUSION, SITTING DROP, temperature 277K
Resolution 2.20 Å R-free 0.222
4DH7 Low temperature X-ray structure of cAMP dependent Protein Kinase A catalytic subunit with high Mg2+, AMP-PNP and IP20' Deposited 2012-01-27 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 2–351（350 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) MG MAGNESIUM ION × 2 ANP PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.5；277 K；50 mM MES (pH=6.5), 50 mM Mg2Cl, 5 mM DTT and 12-15% PEG4000, VAPOR DIFFUSION, SITTING DROP, temperature 277K
Resolution 1.80 Å R-free 0.194
4DH8 Room temperature X-ray structure of cAMP dependent Protein Kinase A catalytic subunit with high Mg2+, AMP-PNP and IP20 Deposited 2012-01-27 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 2–351（350 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) MG MAGNESIUM ION × 2 ANP PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.5；277 K；50 mM MES (pH=6.5), 50 mM Mg2Cl, 5 mM DTT and 12-15% PEG4000, VAPOR DIFFUSION, SITTING DROP, temperature 277K
Resolution 2.30 Å R-free 0.188
4DIN Novel Localization and Quaternary Structure of the PKA RI beta Holoenzyme Deposited 2012-01-31 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 2–351（350 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) ATP ADENOSINE-5'-TRIPHOSPHATE × 1 MG MAGNESIUM ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.3；277 K；1.4 M ammonium sulfate, 0.1M Sodium Acetate pH 5.3, VAPOR DIFFUSION, HANGING DROP, temperature 277K
Resolution 3.70 Å R-free 0.293
4HPT Crystal structure of the catalytic subunit of cAMP-dependent protein kinase displaying complete phosphoryl transfer of AMP-PNP onto a substrate peptide Deposited 2012-10-24 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain E 2–351（350 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) ANP PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER × 1 MG MAGNESIUM ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8；277.15 K；Protein buffer: 50 mM Bicine, 150 mM Ammonium Acetate, 10 mM DTT, ~7-10 mg/mL protein Well Solution: 1 mL of 2% MPD, 80 uL methanol added to the well immediately before sealing 8 uL drops of 1:1 protein:well were used., VAPOR DIFFUSION, HANGING DROP, temperature 277.15K, pH 8.0
Resolution 2.15 Å R-free 0.228
4HPU Crystal structure of the catalytic subunit of cAMP-dependent protein kinase displaying partial phosphoryl transfer of AMP-PNP onto a substrate peptide Deposited 2012-10-24 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain E 2–351（350 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) MYR MYRISTIC ACID × 1 ANP PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER × 2 MG MAGNESIUM ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8；277.15 K；50 mM Bicine, 150 mM Ammonium acetate, 10 mM DTT, ~7-10 mg/mL protein Well solution: 2% MPD in a 1 mL well. 80 uL of methanol was added to the well immediately before sealing. Drop was 8 uL of 1:1 protein:well, VAPOR DIFFUSION, HANGING DROP, temperature 277.15K, pH 8.0
Resolution 1.55 Å R-free 0.194
4IAC X-RAY structure of cAMP dependent protein kinase A in complex with HIGH MG2+ concentration, AMP-PCP AND pseudo-substrate peptide SP20 Deposited 2012-12-06 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 2–351（350 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) MG MAGNESIUM ION × 2 ACP PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.5；277 K；100 mM MES pH 6.5, 5 mM DTT, 15-20% PEG 4000, VAPOR DIFFUSION, SITTING DROP, temperature 277K
Resolution 2.15 Å R-free 0.212
4IAD Low temperature X-ray Structure OF cAMP dependent protein kinase A in complex with high Mg2+ concentration, ADP and phosphorylated peptide pSP20 Deposited 2012-12-06 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 2–351（350 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) MG MAGNESIUM ION × 2 ADP ADENOSINE-5'-DIPHOSPHATE × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.5；277 K；100 mM MES pH 6.5, 5 mM DTT, 15-20% PEG 4000, VAPOR DIFFUSION, SITTING DROP, temperature 277K
Resolution 1.90 Å R-free 0.243
4IAF Room temperature X-ray Structure OF cAMP dependent protein kinase A in complex with high Mg2+ concentration, ADP and phosphorylated peptide pSP20 Deposited 2012-12-06 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 2–351（350 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) MG MAGNESIUM ION × 2 ADP ADENOSINE-5'-DIPHOSPHATE × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.5；277 K；100 mM MES pH 6.5, 5 mM DTT, 15-20% PEG 4000, VAPOR DIFFUSION, SITTING DROP, temperature 277K
Resolution 2.20 Å R-free 0.192
4IAI X-ray Structure of cAMP dependent protein kinase A in complex with high Ca2+ concentration, ADP and phosphorylated peptide pSP20 Deposited 2012-12-06 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 2–351（350 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) CA CALCIUM ION × 2 ADP ADENOSINE-5'-DIPHOSPHATE × 1 CO3 CARBONATE ION × 1 PEG DI(HYDROXYETHYL)ETHER × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.5；277 K；100 mM MES pH 6.5, 5 mM DTT, 15-20% PEG 4000, VAPOR DIFFUSION, SITTING DROP, temperature 277K
Resolution 1.55 Å R-free 0.209
4IAK Low temperature X-ray structure of cAMP dependent protein kinase A in complex with high Sr2+ concentration, ADP and phosphorylated peptide pSP20 Deposited 2012-12-06 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 2–351（350 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) SR STRONTIUM ION × 2 ADP ADENOSINE-5'-DIPHOSPHATE × 1 CO3 CARBONATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.5；277 K；100 mM MES pH 6.5, 5 mM DTT, 15-20% PEG 4000, VAPOR DIFFUSION, SITTING DROP, temperature 277K
Resolution 1.60 Å R-free 0.222
4IAY Room temperature X-ray Structure of cAMP dependent protein kinase A in complex with high Sr2+ concentration, ADP and phosphorylated peptide pSP20 Deposited 2012-12-07 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 2–351（350 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) SR STRONTIUM ION × 2 ADP ADENOSINE-5'-DIPHOSPHATE × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.5；277 K；100 mM MES pH 6.5, 5 mM DTT, 15-20% PEG 4000, VAPOR DIFFUSION, SITTING DROP, temperature 277K
Resolution 2.00 Å R-free 0.227
4IAZ Structure of cAMP dependent protein kinase A in complex with high Ba2+ concentration, ADP and phosphorylated peptide pSP20 Deposited 2012-12-07 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 2–351（350 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) BA BARIUM ION × 2 ADP ADENOSINE-5'-DIPHOSPHATE × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.5；277 K；100 mM MES pH 6.5, 5 mM DTT, 15-20% PEG 4000, VAPOR DIFFUSION, SITTING DROP, temperature 277K
Resolution 1.85 Å R-free 0.248
4IB0 X-ray Structure of cAMP dependent protein kinase A in complex with high Na+ concentration, ADP and phosphorylated peptide pSP20 Deposited 2012-12-07 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 2–351（350 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) NA SODIUM ION × 2 ADP ADENOSINE-5'-DIPHOSPHATE × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.5；277 K；100 mM MES pH 6.5, 5 mM DTT, 15-20% PEG 4000, VAPOR DIFFUSION, SITTING DROP, temperature 277K
Resolution 1.87 Å R-free 0.287
4IB1 Structure of cAMP dependent protein kinase A in complex with high K+ concentration, ADP and phosphorylated peptide pSP20 Deposited 2012-12-07 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 2–351（350 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) K POTASSIUM ION × 2 ADP ADENOSINE-5'-DIPHOSPHATE × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.5；277 K；100 mM MES pH 6.5, 5 mM DTT, 15-20% PEG 4000, VAPOR DIFFUSION, SITTING DROP, temperature 277K
Resolution 1.63 Å R-free 0.223
4IB3 Structure of cAMP dependent protein kinase A in complex with ADP, phosphorylated peptide pSP20, and no metal Deposited 2012-12-07 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 2–351（350 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) ADP ADENOSINE-5'-DIPHOSPHATE × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.5；277 K；100 mM MES pH 6.5, 5 mM DTT, 0.3M EDTA, 15-20% PEG 4000, VAPOR DIFFUSION, SITTING DROP, temperature 277K
Resolution 2.20 Å R-free 0.228
4NTS Apo structure of the catalytic subunit of cAMP-dependent protein kinase Deposited 2013-12-02 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 2–351（350 aa）
Mutation：K7C Non-standard monomer：Yes (specific site not provided by mmCIF) MYR MYRISTIC ACID × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8；277.15 K；8% MPD, 0.1 M Bicine, 150 mM Ammonium Acetate, 10 mM DTT, 9% methanol added to the well solution, pH 8.0, VAPOR DIFFUSION, HANGING DROP, temperature 277.15K
Resolution 2.90 Å R-free 0.292
4NTS Apo structure of the catalytic subunit of cAMP-dependent protein kinase Deposited 2013-12-02 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain B 2–351（350 aa）
Mutation：K7C Non-standard monomer：Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8；277.15 K；8% MPD, 0.1 M Bicine, 150 mM Ammonium Acetate, 10 mM DTT, 9% methanol added to the well solution, pH 8.0, VAPOR DIFFUSION, HANGING DROP, temperature 277.15K
Resolution 2.90 Å R-free 0.292
4NTT Structure of the catalytic subunit of cAMP-dependent protein kinase bound to ADP and one magnesium ion Deposited 2013-12-02 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 2–351（350 aa）
Mutation：K7C Non-standard monomer：Yes (specific site not provided by mmCIF) ADP ADENOSINE-5'-DIPHOSPHATE × 1 MG MAGNESIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8；277.15 K；8% MPD, 0.1 M Bicine, 150 mM Ammonium Acetate, 10 mM DTT, 9% methanol added to the well, pH 8.0, VAPOR DIFFUSION, HANGING DROP, temperature 277.15K
Resolution 3.50 Å R-free 0.284
4NTT Structure of the catalytic subunit of cAMP-dependent protein kinase bound to ADP and one magnesium ion Deposited 2013-12-02 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain B 2–351（350 aa）
Mutation：K7C Non-standard monomer：Yes (specific site not provided by mmCIF) ADP ADENOSINE-5'-DIPHOSPHATE × 1 MG MAGNESIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8；277.15 K；8% MPD, 0.1 M Bicine, 150 mM Ammonium Acetate, 10 mM DTT, 9% methanol added to the well, pH 8.0, VAPOR DIFFUSION, HANGING DROP, temperature 277.15K
Resolution 3.50 Å R-free 0.284
4O21 Product complex of metal-free PKAc, ATP-gamma-S and SP20. Deposited 2013-12-16 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 16–351（336 aa） Fragment：Catalytic subunit, UNP residues 16-351
Non-standard monomer：Yes (specific site not provided by mmCIF) ADP ADENOSINE-5'-DIPHOSPHATE × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.5；277 K；100 mM MES pH 6.5, 5 mM DTT, 15-20% PEG 4000., VAPOR DIFFUSION, SITTING DROP, temperature 277K
Resolution 1.95 Å R-free 0.215
4O22 Binary complex of metal-free PKAc with SP20. Deposited 2013-12-16 Different construct Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 16–351（336 aa） Fragment：Catalytic subunit, UNP residues 16-351
Non-standard monomer：Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.5；277 K；100 mM MES pH 6.5, 5 mM DTT, 15-20% PEG 3350., VAPOR DIFFUSION, SITTING DROP, temperature 277K
Resolution 1.70 Å R-free 0.219
4WBB Single Turnover Autophosphorylation Cycle of the PKA RIIb Holoenzyme Deposited 2014-09-02 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain B 2–351（350 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) CA CALCIUM ION × 2 ADP ADENOSINE-5'-DIPHOSPHATE × 1 X-RAY DIFFRACTION
X-ray crystallization conditions BATCH MODE；298 K；The RIIb (R230K):C apo complex was crystallized in 20%PEG8000, 8% Ethylene Glycol, 20mM MESpH7.5 HEPES . To make CaATP binding holoenzyme crystals, the apo holoenzyme crystals were soaked with 20%PEG8000, 8% Ethylene Glycol, 20mM MESpH7.5 HEPES, 5mM CaCl2 and 1mM ATP at pH5.8 solution overnight
Resolution 2.80 Å R-free 0.279
4X6Q An Isoform-specific Myristylation Switch Targets RIIb PKA Holoenzymes to Membranes Deposited 2014-12-08 Different construct Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain C 2–351（350 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions BATCH MODE；298 K；The RIIb(R230K)2: myrC(K7C)2 holoenzyme was concentrated to 12 mg/mL. The crystal used for structure determination was obtained from a 3 uL drop containing 1:1 protein to well solution with the well solution containing 10% PEG8000, 8% ethylene glycol, 20mM MES, at pH5.8.
Resolution 2.52 Å R-free 0.261
4X6R An Isoform-specific Myristylation Switch Targets RIIb PKA Holoenzymes to Membranes Deposited 2014-12-09 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 2–351（350 aa）
Mutation：K7C Non-standard monomer：Yes (specific site not provided by mmCIF) SO4 SULFATE ION × 6 ATP ADENOSINE-5'-TRIPHOSPHATE × 1 TAM TRIS(HYDROXYETHYL)AMINOMETHANE × 1 GOL GLYCEROL × 2 MYR MYRISTIC ACID × 1 MG MAGNESIUM ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions BATCH MODE；298 K；Crystallization of RIb(91-379,R333K): myrC(K7C) heterodimer :RC heterodimer that was concentrated to 14 mg/mL and screened against different ammonium sulfate concentrations ranging from 0.8-2.5 M in 0.1 M sodium citrate buffer and also varying the pH from 5.0-6.0 using the hanging drop vapor diffusion method. The crystal used for structure determination was obtained from a 4 uL drop containing 1:1 protein to well solution with the well solution containing 1.6 M ammonium sulfate and 0.1 M sodium citrate at pH 5.5
Resolution 2.40 Å R-free 0.234
4XW4 X-ray structure of PKAc with AMPPNP, SP20, calcium ions Deposited 2015-01-28 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 15–351（337 aa） Fragment：UNP residues 15-351
Non-standard monomer：Yes (specific site not provided by mmCIF) CA CALCIUM ION × 2 ANP PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；277 K；100 mM MES pH 6.5, 5 mM DTT, 15-20% PEG 4000
Resolution 1.82 Å R-free 0.240
4XW5 X-ray structure of PKAc with ATP, CP20, calcium ions Deposited 2015-01-28 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 15–351（337 aa） Fragment：UNP residues 15-351
Non-standard monomer：Yes (specific site not provided by mmCIF) CA CALCIUM ION × 2 ATP ADENOSINE-5'-TRIPHOSPHATE × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；277 K；100 mM MES pH 6.5, 5 mM DTT, 15-20% PEG 4000
Resolution 1.95 Å R-free 0.252
4XW6 X-ray structure of PKAc with ADP, free phosphate ion, CP20, magnesium ions Deposited 2015-01-28 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 15–351（337 aa） Fragment：UNP residues 15-351
Non-standard monomer：Yes (specific site not provided by mmCIF) MG MAGNESIUM ION × 2 ADP ADENOSINE-5'-DIPHOSPHATE × 1 PO4 PHOSPHATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；277 K；100 mM MES pH 6.5, 5 mM DTT, 15-20% PEG 4000
Resolution 1.90 Å R-free 0.265
5JR7 Crystal structure of an ACRDYS heterodimer [RIa(92-365):C] of PKA Deposited 2016-05-05 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 2–351（350 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) ADP ADENOSINE-5'-DIPHOSPHATE × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；0.2 M Sodium thiocyanate and 20% PEG 3350 with the protein at a final concentration of 5 mg/ml in a 1.6 ul drop
Resolution 3.56 Å R-free 0.322
5JR7 Crystal structure of an ACRDYS heterodimer [RIa(92-365):C] of PKA Deposited 2016-05-05 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain C 2–351（350 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) ADP ADENOSINE-5'-DIPHOSPHATE × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；0.2 M Sodium thiocyanate and 20% PEG 3350 with the protein at a final concentration of 5 mg/ml in a 1.6 ul drop
Resolution 3.56 Å R-free 0.322
6E21 Joint X-ray/neutron structure of PKAc with products Sr2-ADP and phosphorylated peptide SP20 Deposited 2018-07-10 Different construct Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 2–351（350 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) SR STRONTIUM ION × 2 ADP ADENOSINE-5'-DIPHOSPHATE × 1 Experimental method not declared
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；277 K；100 mM MES, pH 6.5, 5 mM DTT, PEG4000
Resolution not provided
6MM5 Catalytic subunit of cAMP-dependent protein kinase A in complex with RyR2 peptide (2799-2810) Deposited 2018-09-29 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain E 16–351（336 aa） Fragment：residues 16-351
Non-standard monomer：Yes (specific site not provided by mmCIF) MG MAGNESIUM ION × 1 ANP PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER × 1 EDO 1,2-ETHANEDIOL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 8.5；277 K；0.2M trimethylamine N-oxide, 0.1 M tris-HCl, 20% (w/v) PEG monomethyl ether 2K 25% (v/V) ethylene glycol
Resolution 1.95 Å R-free 0.227
6MM6 Catalytic subunit of cAMP-dependent protein kinase A in complex with RyR2 phosphorylation domain (2699-2904) Deposited 2018-09-29 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain C 16–351（336 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) ACT ACETATE ION × 1 ANP PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER × 1 PGE TRIETHYLENE GLYCOL × 1 CL CHLORIDE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7.5；277 K；0.05M HEPES, 0.05 M KCl, 0.01M MgCl2, 15% (w/v) PEG 6K, and 25% (v/v) ethylene glycol
Resolution 2.39 Å R-free 0.261
6MM6 Catalytic subunit of cAMP-dependent protein kinase A in complex with RyR2 phosphorylation domain (2699-2904) Deposited 2018-09-29 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain E 16–351（336 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) ANP PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER × 1 CL CHLORIDE ION × 1 EDO 1,2-ETHANEDIOL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7.5；277 K；0.05M HEPES, 0.05 M KCl, 0.01M MgCl2, 15% (w/v) PEG 6K, and 25% (v/v) ethylene glycol
Resolution 2.39 Å R-free 0.261
6MM7 Catalytic subunit of cAMP-dependent protein kinase A in complex with RyR2 K2879A, S2813D phosphomimetic (2699-2904) crystal form 1 Deposited 2018-09-29 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 16–351（336 aa） Fragment：residues 16-351
Non-standard monomer：Yes (specific site not provided by mmCIF) FMT FORMIC ACID × 4 ACY ACETIC ACID × 1 ANP PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER × 1 EDO 1,2-ETHANEDIOL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7.5；277 K；0.1 M magnesium formate and 25% (w/v) PEG 3350; 0.05 M HEPES, and 25% ethylene glycol
Resolution 1.85 Å R-free 0.238
6MM7 Catalytic subunit of cAMP-dependent protein kinase A in complex with RyR2 K2879A, S2813D phosphomimetic (2699-2904) crystal form 1 Deposited 2018-09-29 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain D 16–351（336 aa） Fragment：residues 16-351
Non-standard monomer：Yes (specific site not provided by mmCIF) FMT FORMIC ACID × 4 ANP PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER × 1 EDO 1,2-ETHANEDIOL × 4 CL CHLORIDE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7.5；277 K；0.1 M magnesium formate and 25% (w/v) PEG 3350; 0.05 M HEPES, and 25% ethylene glycol
Resolution 1.85 Å R-free 0.238
6MM8 Catalytic subunit of cAMP-dependent protein kinase A in complex with RyR2 K2879A, S2813D phosphomimetic (2699-2904) crystal form 2 Deposited 2018-09-29 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain C 16–351（336 aa） Fragment：residues 16-351
Non-standard monomer：Yes (specific site not provided by mmCIF) PEG DI(HYDROXYETHYL)ETHER × 1 ACY ACETIC ACID × 2 ANP PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER × 1 EDO 1,2-ETHANEDIOL × 5 CL CHLORIDE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7.5；277 K；0.15 M HEPES pH 7.5, 15% (w/v) PEG 20k, and 25% (v/v) ethylene glycol
Resolution 1.85 Å R-free 0.221
7E0Z Crystal structure of PKAc-PLN complex Deposited 2021-01-28 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 1–351（351 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) ANP PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER × 1 MG MAGNESIUM ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；298.15 K；0.1M Bis-Tris, pH 6.5, 25% PEG 3350
Resolution 2.16 Å R-free 0.228
7E11 Crystal structure of PKAc-PLN R9C complex Deposited 2021-01-28 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 14–351（338 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) ANP PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER × 1 MG MAGNESIUM ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；298.15 K；0.1 M HEPES, pH 7.5 25% PEG 3350, 0.2 M MgCl2
Resolution 3.43 Å R-free 0.317
7E12 Crystal structure of PKAc-A11E complex Deposited 2021-01-28 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 1–351（351 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) ANP PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER × 1 MG MAGNESIUM ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；298.15 K；0.2 M NaCl, 0.1 M HEPES, pH 7.5, 25% PEG 3350
Resolution 2.80 Å R-free 0.252
7UJX Structure of cAMP-dependent protein kinase using a MD-MX procedure, produced using 2.4 Angstrom data Deposited 2022-03-31 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain E 2–351（350 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) ADP ADENOSINE-5'-DIPHOSPHATE × 1 PO4 PHOSPHATE ION × 2 MG MAGNESIUM ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.5；293 K；20% PEG 4000, 0.05 M MES pH 5.2, 0.05 M MgCl2, and 0.005 M DTT
Resolution 2.40 Å R-free 0.176
7V0G Structure of cAMP-dependent protein kinase using a MD-MX procedure, produced using 1.63 Angstrom data Deposited 2022-05-10 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain E 2–351（350 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) ADP ADENOSINE-5'-DIPHOSPHATE × 1 PO4 PHOSPHATE ION × 2 MG MAGNESIUM ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.5；293 K；20% PEG 4000, 0.05 M MES pH 5.2, 0.05 M MgCl2, and 0.005 M DTT
Resolution 1.63 Å R-free 0.163
8UKN APO and AMP-PNP bound cAMP-dependent protein kinase A catalytic domain Deposited 2023-10-14 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain C 16–351（336 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) EDO 1,2-ETHANEDIOL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7.5；277.115 K；0.1 M HEPES pH 7.5, 10% (w/v) PEG 8000
Resolution 2.75 Å R-free 0.232
8UKN APO and AMP-PNP bound cAMP-dependent protein kinase A catalytic domain Deposited 2023-10-14 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain D 16–351（336 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) ANP PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7.5；277.115 K；0.1 M HEPES pH 7.5, 10% (w/v) PEG 8000
Resolution 2.75 Å R-free 0.232
8UKN APO and AMP-PNP bound cAMP-dependent protein kinase A catalytic domain Deposited 2023-10-14 Different construct Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain F 16–351（336 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7.5；277.115 K；0.1 M HEPES pH 7.5, 10% (w/v) PEG 8000
Resolution 2.75 Å R-free 0.232
8UKN APO and AMP-PNP bound cAMP-dependent protein kinase A catalytic domain Deposited 2023-10-14 Different construct Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain H 16–351（336 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7.5；277.115 K；0.1 M HEPES pH 7.5, 10% (w/v) PEG 8000
Resolution 2.75 Å R-free 0.232
8UKO cAMP-dependent protein kinase A catalytic domain in complex with voltage gated calcium channel peptide ternary complex 2 Deposited 2023-10-14 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain E 16–351（336 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) MG MAGNESIUM ION × 2 ANP PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7；277.15 K；0.1 M Succinic Acid pH 7.0, 15% PEG 3350
Resolution 2.89 Å R-free 0.259
8UKP cAMP-dependent protein kinase A catalytic domain in complex with voltage gated calcium channel peptide ternary complex 1 Deposited 2023-10-14 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain E 16–351（336 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) MG MAGNESIUM ION × 2 ANP PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7；277.15 K；0.1M HEPES pH 7.0, 18% w/v PEG 12K
Resolution 2.85 Å R-free 0.281
9O7V Crystal Structure of the RIb:C Heterodimer of PKA Deposited 2025-04-15 Different construct Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 2–351（350 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.3；293 K；1.4M ammonium sulfate and 0.1M sodium acetate at pH 5.3.
Resolution 3.70 Å R-free 0.293
9PC1 Co-crystal structure of the cAMP-dependent protein kinase catalytic subunit alpha with the inhibitor BLU0588 Deposited 2025-06-26 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain E 2–351（350 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) MPD (4S)-2-METHYL-2,4-PENTANEDIOL × 1 A1CHQ (6M)-N-[(1R,2R)-2-(pyrrolidin-1-yl)-2,3-dihydro-1H-inden-1-yl]-6-(1H-pyrrolo[2,3-b]pyridin-4-yl)pyridine-3-carboxamide × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；277 K；10% MPD, Hepes pH7, 10% Methanol
Resolution 1.55 Å R-free 0.214

84 other PDB entries and 99 assemblies. Open the comparison page and filter oligomeric states

View Construct and Data Evidence
UniProt name KAPCA_MOUSE
Isoform —
PDB entities 2
Chains and sequence ranges Author chain B； PDBConstruct 61–393； UniProt 19–351

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

SAXS scattering curve SAXS Profile

SAXS profile for 5x3f

P(r) Distance Distribution P(r) Distribution

P(r) distribution for 5x3f
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2. Structure Basics 2. Structure Basics

Entry ID entry_id5x3f
Deposition date deposition_date2017-02-05
Structure title titleCrystal structure of the YgjG-Protein A-Zpa963-PKA catalytic domain
Keywords keywordssynthetic protein, LYASE, TRANSFERASE; TRANSFERASE
Experimental Method methodX-RAY DIFFRACTION
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3. SAXS Parameters (CRYSOL theoretical calculation) 3. SAXS Parameters (CRYSOL)

Radius of gyration Rg (Guinier) rg_guinier38.70 Å
Radius of gyration Rg (electron density) rg_electron39.04 Å
Forward intensity I(0) i0127726000.00
Molecular weight molecular_weight93881.0 kDa
Excluded volume excluded_volume118590 ų
Envelope volume envelope_volume162640 ų
Hydration-shell volume shell_volume36696 ų
Envelope diameter envelope_diameter131.6 Å
Shell Rg shell_rg42.15 Å
Envelope Rg envelope_rg38.14 Å
Shape Rg shape_rg39.02 Å
Total Rg total_rg39.29 Å
Total atoms total_atoms6616
Residues n_residues841
Spherical-harmonic order n_harmonics20
q range q_range— – 0.5000 Å−1
Data points n_points101
Shell type shell_typedirectional
Solvent electron density solvent_density0.3340 e/ų
Shell contrast contrast_shell0.0300 e/ų
CRYSOL version crysol_version4.1.3
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4. P(r) Distance Distribution (GNOM inversion) 4. P(r) Analysis (GNOM)

Maximum dimension Dmax dmax131.2 Å
Rg (real space) rg_real39.07 Å
Rg uncertainty (real space) rg_real_error1.26 Å
I(0) (real space) i0_real1.2770e+08
I(0) uncertainty (real space) i0_real_error2.1760e+06
Rg (reciprocal space) rg_reciprocal38.85 Å
I(0) (reciprocal space) i0_reciprocal127700000.0000
Solution quality estimate total_estimate0.8399
Solution quality rating solution_quality GOOD a GOOD solution
P(r) peaks n_peaks1
Primary peak position r_peak_primary32.0 Å
Skewness Skewness skewness0.433
Kurtosis Kurtosis kurtosis-0.611
Angular range angular_range— – 0.2050 Å−1
Current regularization parameter α current_alpha0.0000
Highest regularization parameter α highest_alpha16480000.0000
Real-space data points n_real_points42
GNOM version gnom_version4.1.3
Quality Criteria quality_criteria AN1: 0.000; Oscil: 0.790; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.750; Smooth: 0.794
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5. Crystallography and Experiment 5. Crystallography & Experiment

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6. Entities and Polymers Entities & Polymers (2)

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7. Fold Classification (SCOP + CATH) 4 domains

CATH v4.4 (4 domains)

Domain ID domain_id5x3fA01
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology640 — Aspartate Aminotransferase; domain 2
Homologous superfamily homologous superfamily10 — Type I PLP-dependent aspartate aminotransferase-like (Major domain)
Domain ID domain_id5x3fA02
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily420 — Immunoglobulin FC, subunit C
Domain ID domain_id5x3fB01
Class class3 — Alpha Beta
Architecture architecture30 — 2-Layer Sandwich
Topology topology200 — Phosphorylase Kinase; domain 1
Homologous superfamily homologous superfamily20 — Phosphorylase Kinase; domain 1
Domain ID domain_id5x3fB02
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology510 — Transferase(Phosphotransferase); domain 1
Homologous superfamily homologous superfamily10 — Transferase(Phosphotransferase) domain 1
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8. Citations (1)

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9. Files and Curves (10)