7egp

The structure of SWI/SNF-nucleosome complex

Method: ELECTRON MICROSCOPY
▼

1. Protein Identity and Related Structures Protein Identity & Related Structures

SWI/SNF chromatin-remodeling complex subunit SWI1

Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

UniProt P09547

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–DNA Heteromer Protein 19 DNA 2 SWI/SNF chromatin-remodeling complex subunit SNF5 × 1 (P18480) SWI/SNF complex subunit SWI3 × 2 (P32591) Transcription regulatory protein SNF12 × 1 (P53628) Transcription regulatory protein SNF6 × 1 (P18888) SWI/SNF global transcription activator complex subunit SWP82 × 1 (P43554) Transcription regulatory protein SNF2 × 1 (P22082) Regulator of Ty1 transposition protein 102 × 1 (P53330) Actin-related protein 7 × 1 (Q12406) Actin-like protein ARP9 × 1 (Q05123) Histone H3.2 × 2 (P84233) Histone H4 × 2 (P62799) Histone H2A × 2 (Q6AZJ8) Histone H2B 1.1 × 2 (P02281) DNA (239-MER) × 1 DNA (239-MER) × 1 ADENOSINE-5'-DIPHOSPHATE × 1 BERYLLIUM TRIFLUORIDE ION × 1 MAGNESIUM ION × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SWI1_YEAST
Isoform —
PDB entities 1
Chains and sequence ranges Author chain B; PDBConstruct 1–1064; UniProt 251–1314

SWI/SNF chromatin-remodeling complex subunit SNF5

Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

UniProt P18480

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–DNA Heteromer Protein 19 DNA 2 SWI/SNF chromatin-remodeling complex subunit SWI1 × 1 (P09547) SWI/SNF complex subunit SWI3 × 2 (P32591) Transcription regulatory protein SNF12 × 1 (P53628) Transcription regulatory protein SNF6 × 1 (P18888) SWI/SNF global transcription activator complex subunit SWP82 × 1 (P43554) Transcription regulatory protein SNF2 × 1 (P22082) Regulator of Ty1 transposition protein 102 × 1 (P53330) Actin-related protein 7 × 1 (Q12406) Actin-like protein ARP9 × 1 (Q05123) Histone H3.2 × 2 (P84233) Histone H4 × 2 (P62799) Histone H2A × 2 (Q6AZJ8) Histone H2B 1.1 × 2 (P02281) DNA (239-MER) × 1 DNA (239-MER) × 1 ADENOSINE-5'-DIPHOSPHATE × 1 BERYLLIUM TRIFLUORIDE ION × 1 MAGNESIUM ION × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SNF5_YEAST
Isoform —
PDB entities 2
Chains and sequence ranges Author chain C; PDBConstruct 1–905; UniProt 1–905

SWI/SNF complex subunit SWI3

Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

UniProt P32591

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–DNA Heteromer Protein 19 DNA 2 SWI/SNF chromatin-remodeling complex subunit SWI1 × 1 (P09547) SWI/SNF chromatin-remodeling complex subunit SNF5 × 1 (P18480) Transcription regulatory protein SNF12 × 1 (P53628) Transcription regulatory protein SNF6 × 1 (P18888) SWI/SNF global transcription activator complex subunit SWP82 × 1 (P43554) Transcription regulatory protein SNF2 × 1 (P22082) Regulator of Ty1 transposition protein 102 × 1 (P53330) Actin-related protein 7 × 1 (Q12406) Actin-like protein ARP9 × 1 (Q05123) Histone H3.2 × 2 (P84233) Histone H4 × 2 (P62799) Histone H2A × 2 (Q6AZJ8) Histone H2B 1.1 × 2 (P02281) DNA (239-MER) × 1 DNA (239-MER) × 1 ADENOSINE-5'-DIPHOSPHATE × 1 BERYLLIUM TRIFLUORIDE ION × 1 MAGNESIUM ION × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SWI3_YEAST
Isoform —
PDB entities 3
Chains and sequence ranges Author chain D; PDBConstruct 1–825; UniProt 1–825 Author chain E; PDBConstruct 1–825; UniProt 1–825

Transcription regulatory protein SNF12

Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

UniProt P53628

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–DNA Heteromer Protein 19 DNA 2 SWI/SNF chromatin-remodeling complex subunit SWI1 × 1 (P09547) SWI/SNF chromatin-remodeling complex subunit SNF5 × 1 (P18480) SWI/SNF complex subunit SWI3 × 2 (P32591) Transcription regulatory protein SNF6 × 1 (P18888) SWI/SNF global transcription activator complex subunit SWP82 × 1 (P43554) Transcription regulatory protein SNF2 × 1 (P22082) Regulator of Ty1 transposition protein 102 × 1 (P53330) Actin-related protein 7 × 1 (Q12406) Actin-like protein ARP9 × 1 (Q05123) Histone H3.2 × 2 (P84233) Histone H4 × 2 (P62799) Histone H2A × 2 (Q6AZJ8) Histone H2B 1.1 × 2 (P02281) DNA (239-MER) × 1 DNA (239-MER) × 1 ADENOSINE-5'-DIPHOSPHATE × 1 BERYLLIUM TRIFLUORIDE ION × 1 MAGNESIUM ION × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SNF12_YEAST
Isoform —
PDB entities 4
Chains and sequence ranges Author chain H; PDBConstruct 1–566; UniProt 1–566

Transcription regulatory protein SNF6

Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

UniProt P18888

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–DNA Heteromer Protein 19 DNA 2 SWI/SNF chromatin-remodeling complex subunit SWI1 × 1 (P09547) SWI/SNF chromatin-remodeling complex subunit SNF5 × 1 (P18480) SWI/SNF complex subunit SWI3 × 2 (P32591) Transcription regulatory protein SNF12 × 1 (P53628) SWI/SNF global transcription activator complex subunit SWP82 × 1 (P43554) Transcription regulatory protein SNF2 × 1 (P22082) Regulator of Ty1 transposition protein 102 × 1 (P53330) Actin-related protein 7 × 1 (Q12406) Actin-like protein ARP9 × 1 (Q05123) Histone H3.2 × 2 (P84233) Histone H4 × 2 (P62799) Histone H2A × 2 (Q6AZJ8) Histone H2B 1.1 × 2 (P02281) DNA (239-MER) × 1 DNA (239-MER) × 1 ADENOSINE-5'-DIPHOSPHATE × 1 BERYLLIUM TRIFLUORIDE ION × 1 MAGNESIUM ION × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SNF6_YEAST
Isoform —
PDB entities 5
Chains and sequence ranges Author chain I; PDBConstruct 1–332; UniProt 1–332

SWI/SNF global transcription activator complex subunit SWP82

Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

UniProt P43554

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–DNA Heteromer Protein 19 DNA 2 SWI/SNF chromatin-remodeling complex subunit SWI1 × 1 (P09547) SWI/SNF chromatin-remodeling complex subunit SNF5 × 1 (P18480) SWI/SNF complex subunit SWI3 × 2 (P32591) Transcription regulatory protein SNF12 × 1 (P53628) Transcription regulatory protein SNF6 × 1 (P18888) Transcription regulatory protein SNF2 × 1 (P22082) Regulator of Ty1 transposition protein 102 × 1 (P53330) Actin-related protein 7 × 1 (Q12406) Actin-like protein ARP9 × 1 (Q05123) Histone H3.2 × 2 (P84233) Histone H4 × 2 (P62799) Histone H2A × 2 (Q6AZJ8) Histone H2B 1.1 × 2 (P02281) DNA (239-MER) × 1 DNA (239-MER) × 1 ADENOSINE-5'-DIPHOSPHATE × 1 BERYLLIUM TRIFLUORIDE ION × 1 MAGNESIUM ION × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SWP82_YEAST
Isoform —
PDB entities 6
Chains and sequence ranges Author chain J; PDBConstruct 1–623; UniProt 1–623

Transcription regulatory protein SNF2

Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

UniProt P22082

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–DNA Heteromer Protein 19 DNA 2 SWI/SNF chromatin-remodeling complex subunit SWI1 × 1 (P09547) SWI/SNF chromatin-remodeling complex subunit SNF5 × 1 (P18480) SWI/SNF complex subunit SWI3 × 2 (P32591) Transcription regulatory protein SNF12 × 1 (P53628) Transcription regulatory protein SNF6 × 1 (P18888) SWI/SNF global transcription activator complex subunit SWP82 × 1 (P43554) Regulator of Ty1 transposition protein 102 × 1 (P53330) Actin-related protein 7 × 1 (Q12406) Actin-like protein ARP9 × 1 (Q05123) Histone H3.2 × 2 (P84233) Histone H4 × 2 (P62799) Histone H2A × 2 (Q6AZJ8) Histone H2B 1.1 × 2 (P02281) DNA (239-MER) × 1 DNA (239-MER) × 1 ADENOSINE-5'-DIPHOSPHATE × 1 BERYLLIUM TRIFLUORIDE ION × 1 MAGNESIUM ION × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SNF2_YEAST
Isoform —
PDB entities 7
Chains and sequence ranges Author chain A; PDBConstruct 1–971; UniProt 430–1400

Regulator of Ty1 transposition protein 102

Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

UniProt P53330

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–DNA Heteromer Protein 19 DNA 2 SWI/SNF chromatin-remodeling complex subunit SWI1 × 1 (P09547) SWI/SNF chromatin-remodeling complex subunit SNF5 × 1 (P18480) SWI/SNF complex subunit SWI3 × 2 (P32591) Transcription regulatory protein SNF12 × 1 (P53628) Transcription regulatory protein SNF6 × 1 (P18888) SWI/SNF global transcription activator complex subunit SWP82 × 1 (P43554) Transcription regulatory protein SNF2 × 1 (P22082) Actin-related protein 7 × 1 (Q12406) Actin-like protein ARP9 × 1 (Q05123) Histone H3.2 × 2 (P84233) Histone H4 × 2 (P62799) Histone H2A × 2 (Q6AZJ8) Histone H2B 1.1 × 2 (P02281) DNA (239-MER) × 1 DNA (239-MER) × 1 ADENOSINE-5'-DIPHOSPHATE × 1 BERYLLIUM TRIFLUORIDE ION × 1 MAGNESIUM ION × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name RT102_YEAST
Isoform —
PDB entities 8
Chains and sequence ranges Author chain L; PDBConstruct 1–157; UniProt 1–157

Actin-related protein 7

Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

UniProt Q12406

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–DNA Heteromer Protein 19 DNA 2 SWI/SNF chromatin-remodeling complex subunit SWI1 × 1 (P09547) SWI/SNF chromatin-remodeling complex subunit SNF5 × 1 (P18480) SWI/SNF complex subunit SWI3 × 2 (P32591) Transcription regulatory protein SNF12 × 1 (P53628) Transcription regulatory protein SNF6 × 1 (P18888) SWI/SNF global transcription activator complex subunit SWP82 × 1 (P43554) Transcription regulatory protein SNF2 × 1 (P22082) Regulator of Ty1 transposition protein 102 × 1 (P53330) Actin-like protein ARP9 × 1 (Q05123) Histone H3.2 × 2 (P84233) Histone H4 × 2 (P62799) Histone H2A × 2 (Q6AZJ8) Histone H2B 1.1 × 2 (P02281) DNA (239-MER) × 1 DNA (239-MER) × 1 ADENOSINE-5'-DIPHOSPHATE × 1 BERYLLIUM TRIFLUORIDE ION × 1 MAGNESIUM ION × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name ARP7_YEAST
Isoform —
PDB entities 9
Chains and sequence ranges Author chain M; PDBConstruct 1–477; UniProt 1–477

Actin-like protein ARP9

Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

UniProt Q05123

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–DNA Heteromer Protein 19 DNA 2 SWI/SNF chromatin-remodeling complex subunit SWI1 × 1 (P09547) SWI/SNF chromatin-remodeling complex subunit SNF5 × 1 (P18480) SWI/SNF complex subunit SWI3 × 2 (P32591) Transcription regulatory protein SNF12 × 1 (P53628) Transcription regulatory protein SNF6 × 1 (P18888) SWI/SNF global transcription activator complex subunit SWP82 × 1 (P43554) Transcription regulatory protein SNF2 × 1 (P22082) Regulator of Ty1 transposition protein 102 × 1 (P53330) Actin-related protein 7 × 1 (Q12406) Histone H3.2 × 2 (P84233) Histone H4 × 2 (P62799) Histone H2A × 2 (Q6AZJ8) Histone H2B 1.1 × 2 (P02281) DNA (239-MER) × 1 DNA (239-MER) × 1 ADENOSINE-5'-DIPHOSPHATE × 1 BERYLLIUM TRIFLUORIDE ION × 1 MAGNESIUM ION × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name ARP9_YEAST
Isoform —
PDB entities 10
Chains and sequence ranges Author chain N; PDBConstruct 1–467; UniProt 1–467

Histone H3.2

Xenopus laevis

UniProt P84233

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–DNA Heteromer Protein 19 DNA 2 SWI/SNF chromatin-remodeling complex subunit SWI1 × 1 (P09547) SWI/SNF chromatin-remodeling complex subunit SNF5 × 1 (P18480) SWI/SNF complex subunit SWI3 × 2 (P32591) Transcription regulatory protein SNF12 × 1 (P53628) Transcription regulatory protein SNF6 × 1 (P18888) SWI/SNF global transcription activator complex subunit SWP82 × 1 (P43554) Transcription regulatory protein SNF2 × 1 (P22082) Regulator of Ty1 transposition protein 102 × 1 (P53330) Actin-related protein 7 × 1 (Q12406) Actin-like protein ARP9 × 1 (Q05123) Histone H4 × 2 (P62799) Histone H2A × 2 (Q6AZJ8) Histone H2B 1.1 × 2 (P02281) DNA (239-MER) × 1 DNA (239-MER) × 1 ADENOSINE-5'-DIPHOSPHATE × 1 BERYLLIUM TRIFLUORIDE ION × 1 MAGNESIUM ION × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name H32_XENLA
Isoform —
PDB entities 11
Chains and sequence ranges Author chain O; PDBConstruct 1–135; UniProt 2–136 Author chain S; PDBConstruct 1–135; UniProt 2–136

Histone H4

Xenopus laevis

UniProt P62799

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–DNA Heteromer Protein 19 DNA 2 SWI/SNF chromatin-remodeling complex subunit SWI1 × 1 (P09547) SWI/SNF chromatin-remodeling complex subunit SNF5 × 1 (P18480) SWI/SNF complex subunit SWI3 × 2 (P32591) Transcription regulatory protein SNF12 × 1 (P53628) Transcription regulatory protein SNF6 × 1 (P18888) SWI/SNF global transcription activator complex subunit SWP82 × 1 (P43554) Transcription regulatory protein SNF2 × 1 (P22082) Regulator of Ty1 transposition protein 102 × 1 (P53330) Actin-related protein 7 × 1 (Q12406) Actin-like protein ARP9 × 1 (Q05123) Histone H3.2 × 2 (P84233) Histone H2A × 2 (Q6AZJ8) Histone H2B 1.1 × 2 (P02281) DNA (239-MER) × 1 DNA (239-MER) × 1 ADENOSINE-5'-DIPHOSPHATE × 1 BERYLLIUM TRIFLUORIDE ION × 1 MAGNESIUM ION × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name H4_XENLA
Isoform —
PDB entities 12
Chains and sequence ranges Author chain P; PDBConstruct 1–102; UniProt 2–103 Author chain T; PDBConstruct 1–102; UniProt 2–103

Histone H2A

Xenopus laevis

UniProt Q6AZJ8

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–DNA Heteromer Protein 19 DNA 2 SWI/SNF chromatin-remodeling complex subunit SWI1 × 1 (P09547) SWI/SNF chromatin-remodeling complex subunit SNF5 × 1 (P18480) SWI/SNF complex subunit SWI3 × 2 (P32591) Transcription regulatory protein SNF12 × 1 (P53628) Transcription regulatory protein SNF6 × 1 (P18888) SWI/SNF global transcription activator complex subunit SWP82 × 1 (P43554) Transcription regulatory protein SNF2 × 1 (P22082) Regulator of Ty1 transposition protein 102 × 1 (P53330) Actin-related protein 7 × 1 (Q12406) Actin-like protein ARP9 × 1 (Q05123) Histone H3.2 × 2 (P84233) Histone H4 × 2 (P62799) Histone H2B 1.1 × 2 (P02281) DNA (239-MER) × 1 DNA (239-MER) × 1 ADENOSINE-5'-DIPHOSPHATE × 1 BERYLLIUM TRIFLUORIDE ION × 1 MAGNESIUM ION × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name Q6AZJ8_XENLA
Isoform —
PDB entities 13
Chains and sequence ranges Author chain Q; PDBConstruct 1–129; UniProt 2–130 Author chain U; PDBConstruct 1–129; UniProt 2–130

Histone H2B 1.1

Xenopus laevis

UniProt P02281

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–DNA Heteromer Protein 19 DNA 2 SWI/SNF chromatin-remodeling complex subunit SWI1 × 1 (P09547) SWI/SNF chromatin-remodeling complex subunit SNF5 × 1 (P18480) SWI/SNF complex subunit SWI3 × 2 (P32591) Transcription regulatory protein SNF12 × 1 (P53628) Transcription regulatory protein SNF6 × 1 (P18888) SWI/SNF global transcription activator complex subunit SWP82 × 1 (P43554) Transcription regulatory protein SNF2 × 1 (P22082) Regulator of Ty1 transposition protein 102 × 1 (P53330) Actin-related protein 7 × 1 (Q12406) Actin-like protein ARP9 × 1 (Q05123) Histone H3.2 × 2 (P84233) Histone H4 × 2 (P62799) Histone H2A × 2 (Q6AZJ8) DNA (239-MER) × 1 DNA (239-MER) × 1 ADENOSINE-5'-DIPHOSPHATE × 1 BERYLLIUM TRIFLUORIDE ION × 1 MAGNESIUM ION × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name H2B11_XENLA
Isoform —
PDB entities 14
Chains and sequence ranges Author chain R; PDBConstruct 1–122; UniProt 5–126 Author chain V; PDBConstruct 1–122; UniProt 5–126

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

▼

2. Structure Basics 2. Structure Basics

Entry ID entry_id7egp
Deposition date deposition_date2021-03-24
Structure title titleThe structure of SWI/SNF-nucleosome complex
Keywords keywordsChromatin remodeler complex, DNA BINDING PROTEIN; DNA BINDING PROTEIN
Experimental Method methodELECTRON MICROSCOPY
▼

3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

7egp__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

7egp__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 109 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

7egp__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg(Guinier)69.14 Å
Rg (electron density)69.29 Å
Total Rg69.41 Å
Atom count44844
Residues5016
Excluded volume779910 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 7egp__assembly_1__model_1 21-meric (21) Success 4.1.3-1-20251215 (887e7ef) View Download
▶

4. Crystallography and Experiment 4. Crystallography & Experiment

▶

5. Entities and Polymers Entities & Polymers (19)

▶

7. Citations (1)