9wpb
Crystal structure of human transthyretin (TTR) with pryazole-based stabilizer
SAXS Profile
P(r) Distribution
1. Structure Basics
| entry_id | 9wpb |
| deposition_date | 2025-09-08 |
| last_revision | 2026-05-06 |
| title | Crystal structure of human transthyretin (TTR) with pryazole-based stabilizer |
| keywords | Transthyretin, Hydroxyisourate hydrolase, kinetic stabilizer, TRANSPORT PROTEIN; TRANSPORT PROTEIN |
| method | X-RAY DIFFRACTION |
Download Data
2. SAXS Parameters (CRYSOL)
| rg_guinier | 36.24 Å |
| rg_electron | 36.14 Å |
| i0 | 303560000.00 |
| molecular_weight | 95395.0 kDa |
| excluded_volume | 92983 ų |
| envelope_volume | 163940 ų |
| shell_volume | 39049 ų |
| envelope_diameter | 124.2 Å |
| shell_rg | 40.83 Å |
| envelope_rg | 35.94 Å |
| shape_rg | 36.10 Å |
| total_rg | 36.45 Å |
| total_atoms | 7272 |
| n_residues | 928 |
| n_harmonics | 20 |
| q_range | — – 0.5000 Å−1 |
| n_points | 101 |
| shell_type | directional |
| solvent_density | 0.3340 e/ų |
| contrast_shell | 0.0300 e/ų |
| crysol_version | 4.1.3 |
3. P(r) Analysis (GNOM)
| dmax | 117.6 Å |
| rg_real | 36.51 Å |
| rg_real_error | 1.04 Å |
| i0_real | 3.0360e+08 |
| i0_real_error | 5.2800e+06 |
| rg_reciprocal | 36.35 Å |
| i0_reciprocal | 303500000.0000 |
| total_estimate | 0.5976 |
| solution_quality | REASONABLE a REASONABLE solution |
| n_peaks | 2 |
| r_peak_primary | 32.1 Å |
| skewness | 0.445 |
| kurtosis | -0.598 |
| angular_range | — – 0.2200 Å−1 |
| current_alpha | 0.0000 |
| highest_alpha | 85860000.0000 |
| n_real_points | 45 |
| gnom_version | 4.1.3 |
| quality_criteria | AN1: 0.000; Oscil: 0.761; Stabil: 1.000; Sysdev: 0.028; Positv: 1.000; Valcen: 0.804; Smooth: 0.594 |