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Protein Structures and Oligomeric States

Enter a protein name, UniProt accession or PDB ID. Name searches ask you to confirm the protein identity before related structures are queried.

Current Protein Identity：Q9Y230 New Search
38PDB entries
40Biological assembly
146chain/assembly records
Main Difference Dimensions in This Set
Different construct Different mutation/modification Different assembly state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
2CQA Solution structure of RSGI RUH-039, a fragment of C-terminal domain of RuvB-like 2 from human cDNA Deposited 2005-05-19 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 131–212（82 aa） Fragment：C-terminal domain (Residues 132-213)
Not recorded No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 7；298 K；Ionic strength (raw mmCIF value) 120mM；Pressure ambient
NMR sample composition 1.3mM RSGI RUH-039 U-15,13C; 20mM d-Tris-HCl; 100mM NaCl; 1mM d-DTT; 0.02% NaN3; 10% D2O | 90% D2O, 10% D2O
Resolution not provided
2XSZ The dodecameric human RuvBL1:RuvBL2 complex with truncated domains II Deposited 2010-10-01 Assembly 1 Protein heterocomplex Heteromer；Protein × 6 PDB declaration: hexameric（6） Consistent with protein count
Chain D 2–133（132 aa）
Chain D 238–463（226 aa）
Chain E 2–133（132 aa）
Chain E 238–463（226 aa）
Chain F 2–133（132 aa）
Chain F 238–463（226 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) ATP ADENOSINE-5'-TRIPHOSPHATE × 6 X-RAY DIFFRACTION
X-ray crystallization conditions pH 7.5；CRYSTALLIZATION DROPS WERE MIXED FROM EQUAL VOLUMES OF PROTEIN SOLUTION (12 MG/ML, 20MM TRIS-HCL PH 8.0, 200MM NACL, 10% GLYCEROL, 4MM MGCL2, 4MM ADP, 0.5MM TCEP) AND CRYSTALLIZATION SOLUTION (0.2M MGCL2, 30% PEG 400, 0.1M HEPES PH 7.5).
Resolution 3.00 Å R-free 0.205
3UK6 Crystal Structure of the Tip48 (Tip49b) hexamer Deposited 2011-11-09 Assembly 1 Protein homooligomer Homooligomer；Protein × 6 PDB declaration: hexameric（6） Consistent with protein count
Chain A 1–132（132 aa） Fragment：UNP residues 1-132, 239-463
Chain A 239–463（225 aa） Fragment：UNP residues 1-132, 239-463
Chain B 1–132（132 aa） Fragment：UNP residues 1-132, 239-463
Chain B 239–463（225 aa） Fragment：UNP residues 1-132, 239-463
Chain C 1–132（132 aa） Fragment：UNP residues 1-132, 239-463
Chain C 239–463（225 aa） Fragment：UNP residues 1-132, 239-463
Chain D 1–132（132 aa） Fragment：UNP residues 1-132, 239-463
Chain D 239–463（225 aa） Fragment：UNP residues 1-132, 239-463
Chain I 1–132（132 aa） Fragment：UNP residues 1-132, 239-463
Chain I 239–463（225 aa） Fragment：UNP residues 1-132, 239-463
Chain J 1–132（132 aa） Fragment：UNP residues 1-132, 239-463
Chain J 239–463（225 aa） Fragment：UNP residues 1-132, 239-463
Not recorded ADP ADENOSINE-5'-DIPHOSPHATE × 6 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；0.1M Tris-HCL, pH 8.0, 20% PEG 3000, 5% glucose, galactose or trehalose, VAPOR DIFFUSION, SITTING DROP, temperature 293K
Resolution 2.95 Å R-free 0.264
3UK6 Crystal Structure of the Tip48 (Tip49b) hexamer Deposited 2011-11-09 Assembly 2 Protein homooligomer Homooligomer；Protein × 6 PDB declaration: hexameric（6） Consistent with protein count
Chain E 1–132（132 aa） Fragment：UNP residues 1-132, 239-463
Chain E 239–463（225 aa） Fragment：UNP residues 1-132, 239-463
Chain F 1–132（132 aa） Fragment：UNP residues 1-132, 239-463
Chain F 239–463（225 aa） Fragment：UNP residues 1-132, 239-463
Chain G 1–132（132 aa） Fragment：UNP residues 1-132, 239-463
Chain G 239–463（225 aa） Fragment：UNP residues 1-132, 239-463
Chain H 1–132（132 aa） Fragment：UNP residues 1-132, 239-463
Chain H 239–463（225 aa） Fragment：UNP residues 1-132, 239-463
Chain K 1–132（132 aa） Fragment：UNP residues 1-132, 239-463
Chain K 239–463（225 aa） Fragment：UNP residues 1-132, 239-463
Chain L 1–132（132 aa） Fragment：UNP residues 1-132, 239-463
Chain L 239–463（225 aa） Fragment：UNP residues 1-132, 239-463
Not recorded ADP ADENOSINE-5'-DIPHOSPHATE × 6 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；0.1M Tris-HCL, pH 8.0, 20% PEG 3000, 5% glucose, galactose or trehalose, VAPOR DIFFUSION, SITTING DROP, temperature 293K
Resolution 2.95 Å R-free 0.264
5OAF Human Rvb1/Rvb2 heterohexamer in INO80 complex Deposited 2017-06-21 Assembly 1 Protein heterocomplex Heteromer；Protein × 6 PDB declaration: hexameric（6） Consistent with protein count
Chain B 1–463（463 aa）
Chain D 1–463（463 aa）
Chain F 1–463（463 aa）
Not recorded ADP ADENOSINE-5'-DIPHOSPHATE × 6 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.06 Å
6FO1 Human R2TP subcomplex containing 1 RUVBL1-RUVBL2 hexamer bound to 1 RBD domain from RPAP3. Deposited 2018-02-05 Assembly 1 Protein heterocomplex Heteromer；Protein × 7 PDB declaration: heptameric（7） Consistent with protein count
Chain D 1–463（463 aa）
Chain E 1–463（463 aa）
Chain F 1–463（463 aa）
Not recorded ADP ADENOSINE-5'-DIPHOSPHATE × 6 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.57 Å
6H7X First X-ray structure of full-length human RuvB-Like 2. Deposited 2018-07-31 Assembly 1 Protein homooligomer Homooligomer；Protein × 6 PDB declaration: hexameric（6） Consistent with protein count
Chain A 1–463（463 aa）
Not recorded MG MAGNESIUM ION × 18 EDO 1,2-ETHANEDIOL × 42 PEG DI(HYDROXYETHYL)ETHER × 6 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6；303.15 K；PEG 3350, Magnesium Chloride
Resolution 2.89 Å R-free 0.237
6HTS Cryo-EM structure of the human INO80 complex bound to nucleosome Deposited 2018-10-04 Assembly 1 Protein–DNA Heteromer；Protein × 17 PDB declaration: nonadecameric（19） Consistent with all polymers
Chain B 1–463（463 aa）
Chain D 1–463（463 aa）
Chain F 1–463（463 aa）
Not recorded ADP ADENOSINE-5'-DIPHOSPHATE × 6 ZN ZINC ION × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.80 Å
6IGM Cryo-EM Structure of Human SRCAP Complex Deposited 2018-09-25 Assembly 1 Protein heterocomplex Heteromer；Protein × 9 PDB declaration: nonameric（9） Consistent with protein count
Chain B 1–463（463 aa）
Chain D 1–463（463 aa）
Chain F 1–463（463 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.00 Å
6K0R Ruvbl1-Ruvbl2 with truncated domain II in complex with phosphorylated Cordycepin Deposited 2019-05-07 Assembly 1 Protein heterocomplex Heteromer；Protein × 6 PDB declaration: hexameric（6） Consistent with protein count
Chain D 1–133（133 aa）
Chain D 238–463（226 aa）
Chain E 1–133（133 aa）
Chain E 238–463（226 aa）
Chain F 1–133（133 aa）
Chain F 238–463（226 aa）
Not recorded ADP ADENOSINE-5'-DIPHOSPHATE × 1 CUU [(2~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-4-oxidanyl-oxolan-2-yl]methyl phosphono hydrogen phosphate × 4 MG MAGNESIUM ION × 1 3AT 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；277 K；0.1 M HEPES-Na pH 7.5-7.6, 0.2 M MgCl2, 20-21 % PEG400
Resolution 2.50 Å R-free 0.269
6K0R Ruvbl1-Ruvbl2 with truncated domain II in complex with phosphorylated Cordycepin Deposited 2019-05-07 Assembly 2 Protein heterocomplex Heteromer；Protein × 6 PDB declaration: hexameric（6） Consistent with protein count
Chain J 1–133（133 aa）
Chain J 238–463（226 aa）
Chain K 1–133（133 aa）
Chain K 238–463（226 aa）
Chain L 1–133（133 aa）
Chain L 238–463（226 aa）
Not recorded CUU [(2~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-4-oxidanyl-oxolan-2-yl]methyl phosphono hydrogen phosphate × 4 MG MAGNESIUM ION × 1 3AT 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE × 1 CU0 [(2~{R},3~{S},4~{S})-3,4-bis(oxidanyl)oxolan-2-yl]methyl phosphono hydrogen phosphate × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；277 K；0.1 M HEPES-Na pH 7.5-7.6, 0.2 M MgCl2, 20-21 % PEG400
Resolution 2.50 Å R-free 0.269
6QI8 Truncated human R2TP complex, structure 3 (ADP-filled) Deposited 2019-01-18 Assembly 1 Protein heterocomplex Heteromer；Protein × 6 PDB declaration: hexameric（6） Consistent with protein count
Chain D 1–463（463 aa）
Chain E 1–463（463 aa）
Chain F 1–463（463 aa）
Not recorded ADP ADENOSINE-5'-DIPHOSPHATE × 6 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.75 Å
6QI9 Truncated human R2TP complex, structure 4 (ADP-empty) Deposited 2019-01-18 Assembly 1 Protein heterocomplex Heteromer；Protein × 6 PDB declaration: hexameric（6） Consistent with protein count
Chain D 1–463（463 aa）
Chain E 1–463（463 aa）
Chain F 1–463（463 aa）
Not recorded ADP ADENOSINE-5'-DIPHOSPHATE × 5 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.63 Å
7AHO RUVBL1-RUVBL2 heterohexameric ring after binding of RNA helicase DHX34 Deposited 2020-09-25 Assembly 1 Protein heterocomplex Heteromer；Protein × 6 PDB declaration: hexameric（6） Consistent with protein count
Chain D 1–463（463 aa）
Chain E 1–463（463 aa）
Chain F 1–463（463 aa）
Not recorded ADP ADENOSINE-5'-DIPHOSPHATE × 3 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4；50 mM Tris-HCl pH 7.4, 150 mM NaCl
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.18 Å
7OLE Cryo-EM structure of the TELO2-TTI1-TTI2-RUVBL1-RUVBL2 complex Deposited 2021-05-19 Assembly 1 Protein heterocomplex Heteromer；Protein × 9 PDB declaration: nonameric（9） Consistent with protein count
Chain B 1–463（463 aa）
Chain D 1–463（463 aa）
Chain F 1–463（463 aa）
Not recorded ADP ADENOSINE-5'-DIPHOSPHATE × 5 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5；Solutions were made fresh for protein purification
cryo-EM vitrification conditions Cryogen ETHANE-PROPANE；3sec
Resolution 3.41 Å
7P6X Cryo-Em structure of the hexameric RUVBL1-RUVBL2 in complex with ZNHIT2 Deposited 2021-07-18 Assembly 1 Protein heterocomplex Heteromer；Protein × 6 PDB declaration: hexameric（6） Consistent with protein count
Chain D 1–463（463 aa）
Chain E 1–463（463 aa）
Chain F 1–463（463 aa）
Not recorded ADP ADENOSINE-5'-DIPHOSPHATE × 3 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.10 Å
7ZI4 Cryo-EM structure of the human INO80 complex bound to a WT nucleosome Deposited 2022-04-07 Assembly 1 Protein–DNA Heteromer；Protein × 18 PDB declaration: eicosameric（20） Consistent with all polymers
Chain B 1–463（463 aa）
Chain D 1–463（463 aa）
Chain F 1–463（463 aa）
Not recorded ADP ADENOSINE-5'-DIPHOSPHATE × 8 BEF BERYLLIUM TRIFLUORIDE ION × 1 ZN ZINC ION × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE；4uL of sample applied to Quantifoil R2/2 Cu 300 mesh grids. blot parameters were wait time 30 sec, blot time 0.5 sec, blot force -8
Resolution 3.20 Å
8QR1 Cryo-EM structure of the human Tip60 complex Deposited 2023-10-06 Assembly 1 Protein heterocomplex Heteromer；Protein × 13 PDB declaration: 13-meric（13） Consistent with protein count
Chain D 1–463（463 aa）
Chain H 1–463（463 aa）
Chain J 1–463（463 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.40 Å
8X15 Structure of nucleosome-bound SRCAP-C in the apo state Deposited 2023-11-06 Assembly 1 Protein–DNA Heteromer；Protein × 23 PDB declaration: 25-meric（25） Consistent with all polymers
Chain N 1–463（463 aa）
Chain P 1–463（463 aa）
Chain R 1–463（463 aa）
Not recorded ADP ADENOSINE-5'-DIPHOSPHATE × 6 ATP ADENOSINE-5'-TRIPHOSPHATE × 2 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.20 Å
8X19 Structure of nucleosome-bound SRCAP-C in the ADP-BeFx-bound state Deposited 2023-11-06 Assembly 1 Protein–DNA Heteromer；Protein × 23 PDB declaration: 25-meric（25） Consistent with all polymers
Chain N 1–463（463 aa）
Chain P 1–463（463 aa）
Chain R 1–463（463 aa）
Not recorded ADP ADENOSINE-5'-DIPHOSPHATE × 7 MG MAGNESIUM ION × 1 BEF BERYLLIUM TRIFLUORIDE ION × 1 ATP ADENOSINE-5'-TRIPHOSPHATE × 2 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.20 Å
8X1C Structure of nucleosome-bound SRCAP-C in the ADP-bound state Deposited 2023-11-06 Assembly 1 Protein–DNA Heteromer；Protein × 23 PDB declaration: 25-meric（25） Consistent with all polymers
Chain N 1–463（463 aa）
Chain P 1–463（463 aa）
Chain R 1–463（463 aa）
Not recorded ADP ADENOSINE-5'-DIPHOSPHATE × 7 ATP ADENOSINE-5'-TRIPHOSPHATE × 3 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.20 Å
8XVG Structure of human NuA4/TIP60 complex Deposited 2024-01-15 Assembly 1 Protein heterocomplex Heteromer；Protein × 14 PDB declaration: tetradecameric（14） Consistent with protein count
Chain B 1–463（463 aa）
Chain D 1–463（463 aa）
Chain F 1–463（463 aa）
Not recorded IHP INOSITOL HEXAKISPHOSPHATE × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 9 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 9.40 Å
8XVT The core subcomplex of human NuA4/TIP60 complex Deposited 2024-01-15 Assembly 1 Protein heterocomplex Heteromer；Protein × 13 PDB declaration: tridecameric（13） Consistent with protein count
Chain B 1–463（463 aa）
Chain D 1–463（463 aa）
Chain F 1–463（463 aa）
Not recorded ADP ADENOSINE-5'-DIPHOSPHATE × 9 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.20 Å
9C57 Reconstituted P400 Subcomplex of the human TIP60 complex Deposited 2024-06-05 Assembly 1 Protein heterocomplex Heteromer；Protein × 13 PDB declaration: tridecameric（13） Consistent with protein count
Chain B 1–463（463 aa）
Chain D 1–463（463 aa）
Chain F 1–463（463 aa）
Not recorded AGS PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER × 7 ATP ADENOSINE-5'-TRIPHOSPHATE × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.75 Å
9C62 P400 subcomplex of the native human TIP60 complex Deposited 2024-06-07 Assembly 1 Protein heterocomplex Heteromer；Protein × 15 PDB declaration: pentadecameric（15） Consistent with protein count
Chain B 1–463（463 aa）
Chain D 1–463（463 aa）
Chain F 1–463（463 aa）
Not recorded ADP ADENOSINE-5'-DIPHOSPHATE × 6 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 5.28 Å
9CA7 Cryo-EM structure of human SRCAP-nucleosome complex in the fully-engaged state (composite structure) Deposited 2024-06-17 Assembly 1 Protein–DNA Heteromer；Protein × 18 PDB declaration: 20-meric（20） Consistent with all polymers
Chain F 1–463（463 aa）
Chain H 1–463（463 aa）
Chain J 1–463（463 aa）
Not recorded AGS PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER × 2 MG MAGNESIUM ION × 5 ZN ZINC ION × 2 ADP ADENOSINE-5'-DIPHOSPHATE × 6 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.6
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.35 Å
9CA8 Cryo-EM structure of human SRCAP-nucleosome complex in the partially-engaged state (composite structure) Deposited 2024-06-17 Assembly 1 Protein–DNA Heteromer；Protein × 18 PDB declaration: 20-meric（20） Consistent with all polymers
Chain F 1–463（463 aa）
Chain H 1–463（463 aa）
Chain J 1–463（463 aa）
Not recorded AGS PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER × 2 MG MAGNESIUM ION × 5 ZN ZINC ION × 2 ADP ADENOSINE-5'-DIPHOSPHATE × 6 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.6
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.92 Å
9CA9 Cryo-EM structure of the human SRCAP complex in the unbound state (composite structure) Deposited 2024-06-17 Assembly 1 Protein heterocomplex Heteromer；Protein × 10 PDB declaration: decameric（10） Consistent with protein count
Chain F 1–463（463 aa）
Chain H 1–463（463 aa）
Chain J 1–463（463 aa）
Not recorded AGS PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER × 1 MG MAGNESIUM ION × 4 ZN ZINC ION × 2 ADP ADENOSINE-5'-DIPHOSPHATE × 6 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.6
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.56 Å
9CAA Cryo-EM structure of human SRCAP-nucleosome complex in the pre-engaged state (composite structure) Deposited 2024-06-17 Assembly 1 Protein–DNA Heteromer；Protein × 18 PDB declaration: 20-meric（20） Consistent with all polymers
Chain F 1–463（463 aa）
Chain H 1–463（463 aa）
Chain J 1–463（463 aa）
Not recorded AGS PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER × 1 MG MAGNESIUM ION × 4 ZN ZINC ION × 2 ADP ADENOSINE-5'-DIPHOSPHATE × 6 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.6
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.04 Å
9CAB Cryo-EM structure of human SRCAP-nucleosome complex in the encounter state (composite structure) Deposited 2024-06-17 Assembly 1 Protein–DNA Heteromer；Protein × 18 PDB declaration: 20-meric（20） Consistent with all polymers
Chain F 1–463（463 aa）
Chain H 1–463（463 aa）
Chain J 1–463（463 aa）
Not recorded AGS PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER × 2 MG MAGNESIUM ION × 5 ZN ZINC ION × 2 ADP ADENOSINE-5'-DIPHOSPHATE × 6 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.6
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.94 Å
9CAC Cryo-EM structure of the RuvBL lobe of the native human TIP60 complex (composite structure) Deposited 2024-06-17 Assembly 1 Protein heterocomplex Heteromer；Protein × 13 PDB declaration: 13-meric（13） Consistent with protein count
Chain F 1–463（463 aa）
Chain H 1–463（463 aa）
Chain J 1–463（463 aa）
Not recorded ADP ADENOSINE-5'-DIPHOSPHATE × 7 MG MAGNESIUM ION × 8 ATP ADENOSINE-5'-TRIPHOSPHATE × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.6
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.43 Å
9CAE Cryo-EM structure of the reconstituted RuvBL lobe of the human TIP60 complex (composite structure) Deposited 2024-06-17 Assembly 1 Protein heterocomplex Heteromer；Protein × 12 PDB declaration: 12-meric（12） Consistent with protein count
Chain F 1–463（463 aa）
Chain H 1–463（463 aa）
Chain J 1–463（463 aa）
Not recorded AGS PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER × 8 MG MAGNESIUM ION × 8 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.6
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.07 Å
9EMA RUVBL1/2 in complex with ATP and CB-6644 inhibitor Deposited 2024-03-07 Assembly 1 Protein heterocomplex Heteromer；Protein × 6 PDB declaration: hexameric（6） Consistent with protein count
Chain D 1–463（463 aa）
Chain E 1–463（463 aa）
Chain F 1–463（463 aa）
Not recorded ATP ADENOSINE-5'-TRIPHOSPHATE × 6 A1H5V 5-chloranyl-2-ethoxy-4-fluoranyl-~{N}-[4-[[3-(methoxymethyl)-1-oxidanylidene-6,7-dihydro-5~{H}-pyrazolo[1,2-a][1,2]benzodiazepin-2-yl]amino]-2,2-dimethyl-4-oxidanylidene-butyl]benzamide × 3 MG MAGNESIUM ION × 4 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE-PROPANE
Resolution 2.40 Å
9EMC RUVBL1/2 in complex with ATP Deposited 2024-03-11 Assembly 1 Protein heterocomplex Heteromer；Protein × 6 PDB declaration: hexameric（6） Consistent with protein count
Chain D 1–463（463 aa）
Chain E 1–463（463 aa）
Chain F 1–463（463 aa）
Not recorded ATP ADENOSINE-5'-TRIPHOSPHATE × 6 MG MAGNESIUM ION × 6 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE-PROPANE
Resolution 3.26 Å
9GCG CryoEM structure of the human INO80 core- H2A.Z nucleosome complex Deposited 2024-08-01 Assembly 1 Protein–DNA Heteromer；Protein × 18 PDB declaration: 20-meric（20） Consistent with all polymers
Chain D 1–463（463 aa）
Chain E 1–463（463 aa）
Chain F 1–463（463 aa）
Not recorded ADP ADENOSINE-5'-DIPHOSPHATE × 7 ATP ADENOSINE-5'-TRIPHOSPHATE × 1 ZN ZINC ION × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.43 Å
9GE5 CryoEM structure of the human INO80-Hexasome complex Deposited 2024-08-07 Assembly 1 Protein–DNA Heteromer；Protein × 16 PDB declaration: 18-meric（18） Consistent with all polymers
Chain D 15–453（439 aa）
Chain E 15–453（439 aa）
Chain F 15–453（439 aa）
Not recorded ATP ADENOSINE-5'-TRIPHOSPHATE × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 7 ZN ZINC ION × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.35 Å
9GEV CryoEM structure of the human INO80 core-nucleosome complex state N-6 Deposited 2024-08-07 Assembly 1 Protein–DNA Heteromer；Protein × 18 PDB declaration: 20-meric（20） Consistent with all polymers
Chain D 1–463（463 aa）
Chain E 1–463（463 aa）
Chain F 1–463（463 aa）
Not recorded ADP ADENOSINE-5'-DIPHOSPHATE × 6 ATP ADENOSINE-5'-TRIPHOSPHATE × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.47 Å
9GFB CryoEM structure of the human INO80 core-nucleosome complex state N-7 Deposited 2024-08-08 Assembly 1 Protein–DNA Heteromer；Protein × 18 PDB declaration: 20-meric（20） Consistent with all polymers
Chain D 1–463（463 aa）
Chain E 1–463（463 aa）
Chain F 1–463（463 aa）
Not recorded ATP ADENOSINE-5'-TRIPHOSPHATE × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 6 ZN ZINC ION × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.55 Å
9HB4 Hexameric RuvBL1/RuvBL2 bound to SPAG1 C-ter Deposited 2024-11-05 Assembly 1 Protein heterocomplex Heteromer；Protein × 8 PDB declaration: octameric（8） Consistent with protein count
Chain D 1–463（463 aa）
Chain E 1–463（463 aa）
Chain F 1–463（463 aa）
Not recorded ADP ADENOSINE-5'-DIPHOSPHATE × 6 ELECTRON MICROSCOPY
cryo-EM buffer pH 8；20 mM HEPES, 170 mM NaCL, 2mM MgCl2, 0.5 mM TCEP
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.56 Å
9HPO Docedameric RuvBL1/RuvBL2 Deposited 2024-12-13 Assembly 1 Protein heterocomplex Heteromer；Protein × 12 PDB declaration: 12-meric（12） Consistent with protein count
Chain D 1–463（463 aa）
Chain E 1–463（463 aa）
Chain F 1–463（463 aa）
Chain J 1–463（463 aa）
Chain K 1–463（463 aa）
Chain L 1–463（463 aa）
Not recorded ADP ADENOSINE-5'-DIPHOSPHATE × 12 ELECTRON MICROSCOPY
cryo-EM buffer pH 8；20 mM HEPES, 170 mM NaCL, 2mM MgCl2, 0.5 mM TCEP
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.50 Å

This page presents structural evidence recorded in PDB/mmCIF.“No recorded non-water small molecule” does not prove that the experimental sample was ligand-free; experimental conditions belong to the PDB experiment, while ligands and copy counts are shown for each biological assembly.