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2nb1

P63/p73 hetero-tetramerisation domain

Method: SOLUTION NMR
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Tumor protein 63

Homo sapiens

UniProt Q9H3D4

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 4 Tumor protein p73 × 2 （O15350） Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1rg6 2rmn 2y9t 2y9u

4 assemblies

Homodimer

None

Homotetramer
3zy0 3zy1 4a9z

3 assemblies

Other homooligomers

None

Heteromeric or nucleic-acid complex
2nb1 3qym 3qym 3qym 3qyn 3us0 3us1 3us2 3us2 6fgn 6ru6 6ru7

30 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name P63_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 2–60； UniProt 397–455 Author chain C； PDBConstruct 2–60； UniProt 397–455

Tumor protein p73

Homo sapiens

UniProt O15350

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 4 Tumor protein 63 × 2 （Q9H3D4） Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1cok 1dxs 4a63

3 assemblies

Homodimer
2xwc

1 assemblies

Homotetramer
2kby 2wqi 2wqj 2wtt 2wtt 2wtt 2wtt 5hob 5hob 5hoc

10 assemblies

Other homooligomers
2wqj 2wqj 2wqj 2wqj

4 assemblies

Heteromeric or nucleic-acid complex
2mps 2nb1 3vd0 3vd0 3vd1 3vd1 3vd2 3vd2 4a63 4a63 4a63 4a63

30 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name P73_HUMAN
Isoform —
PDB entities 2
Chains and sequence ranges Author chain B； PDBConstruct 3–50； UniProt 351–398 Author chain D； PDBConstruct 3–50； UniProt 351–398

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id2nb1
Deposition date deposition_date2016-01-19
Structure title titleP63/p73 hetero-tetramerisation domain
Keywords keywordsp63, p73, tetramerization domain, hetero tetramer, transcription factor, TRANSCRIPTION; TRANSCRIPTION
Experimental Method methodSOLUTION NMR
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

2nb1__assembly_1__model_7

Assembly 1 · Model 7 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

2nb1__assembly_1__model_7 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

2nb1__assembly_1__model_7 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）20.93 Å
Rg (electron density)19.61 Å
Total Rg20.56 Å
Atom count3732
Residues220
Excluded volume33197 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 2nb1__assembly_1__model_1 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 2 2nb1__assembly_1__model_2 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 3 2nb1__assembly_1__model_3 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 4 2nb1__assembly_1__model_4 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 5 2nb1__assembly_1__model_5 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 6 2nb1__assembly_1__model_6 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 7 2nb1__assembly_1__model_7 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 8 2nb1__assembly_1__model_8 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 9 2nb1__assembly_1__model_9 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 10 2nb1__assembly_1__model_10 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 11 2nb1__assembly_1__model_11 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 12 2nb1__assembly_1__model_12 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 13 2nb1__assembly_1__model_13 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 14 2nb1__assembly_1__model_14 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 15 2nb1__assembly_1__model_15 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 16 2nb1__assembly_1__model_16 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 17 2nb1__assembly_1__model_17 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 18 2nb1__assembly_1__model_18 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 19 2nb1__assembly_1__model_19 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 20 2nb1__assembly_1__model_20 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (2)

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6. Fold Classification (SCOP + CATH) 8 domains

SCOP 2.08 (8 domains)

Domain ID domain_idd2nb1a1
Class classa — All alpha proteins
Fold Fold folda.53 — p53 tetramerization domain
Superfamily Superfamily superfamilya.53.1 — p53 tetramerization domain
Family Family familya.53.1.0 — automated matches
Domain ID domain_idd2nb1a2
Class classl — Artifacts
Fold Fold foldl.1 — Tags
Superfamily Superfamily superfamilyl.1.1 — Tags
Family Family familyl.1.1.1 — Tags
Domain ID domain_idd2nb1b1
Class classa — All alpha proteins
Fold Fold folda.53 — p53 tetramerization domain
Superfamily Superfamily superfamilya.53.1 — p53 tetramerization domain
Family Family familya.53.1.0 — automated matches
Domain ID domain_idd2nb1b2
Class classl — Artifacts
Fold Fold foldl.1 — Tags
Superfamily Superfamily superfamilyl.1.1 — Tags
Family Family familyl.1.1.1 — Tags
Domain ID domain_idd2nb1c1
Class classa — All alpha proteins
Fold Fold folda.53 — p53 tetramerization domain
Superfamily Superfamily superfamilya.53.1 — p53 tetramerization domain
Family Family familya.53.1.0 — automated matches
Domain ID domain_idd2nb1c2
Class classl — Artifacts
Fold Fold foldl.1 — Tags
Superfamily Superfamily superfamilyl.1.1 — Tags
Family Family familyl.1.1.1 — Tags
Domain ID domain_idd2nb1d1
Class classa — All alpha proteins
Fold Fold folda.53 — p53 tetramerization domain
Superfamily Superfamily superfamilya.53.1 — p53 tetramerization domain
Family Family familya.53.1.0 — automated matches
Domain ID domain_idd2nb1d2
Class classl — Artifacts
Fold Fold foldl.1 — Tags
Superfamily Superfamily superfamilyl.1.1 — Tags
Family Family familyl.1.1.1 — Tags
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7. Citations (1)