Homo sapiens
| Assembly | Physical composition | Protein state | Molecular copy count | Associated components | Data consistency |
|---|---|---|---|---|---|
| 1 | Protein heterocomplex | Heteromer | Protein 2 | H4K5/8ApmTri × 1 water × 2 | Consistent with protein count |
| UniProt name | BRD4_HUMAN |
| Isoform | — |
| PDB entities | 1 |
| Chains and sequence ranges | Author chain A； PDBConstruct 5–129； UniProt 44–168 |
The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.
| Entry ID entry_id | 8b5c |
| Deposition date deposition_date | 2022-09-22 |
| Structure title title | Human BRD4 bromdomain 1 in complex with a H4 peptide containing ApmTri (H4K5/8ApmTri) |
| Keywords keywords | ApmTri, acetyl-lysine mimic, BET-Bromodomain, histone-peptide, PEPTIDE BINDING PROTEIN; PEPTIDE BINDING PROTEIN |
| Experimental Method method | X-RAY DIFFRACTION |
This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
| Rg（Guinier） | 16.24 Å |
| Rg (electron density) | 15.15 Å |
| Total Rg | 16.19 Å |
| Atom count | 1093 |
| Residues | 135 |
| Excluded volume | 19638 ų |
| Maximum q | 0.500 Å⁻¹ |
| Domain ID domain_id | 8b5cA01 |
| Class class | 1 — Mainly Alpha |
| Architecture architecture | 20 — Up-down Bundle |
| Topology topology | 920 — Histone Acetyltransferase; Chain A |
| Homologous superfamily homologous superfamily | 10 — Bromodomain-like |