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9sfp

Native cytoplasmic lattices from mouse oocytes

Method: ELECTRON MICROSCOPY Dmax: 297.2 Å Quality: EXCELLENT
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1. Protein Identity and Related Structures Protein Identity & Related Structures

F-box and WD-40 domain protein 12

OrganismNot specified

UniProt Q5U467

State in the Current Structure

Assembly Oligomeric State Construct Mutations and Modifications Ligands, Ions and Associated Components Method and Experimental Conditions Structure Quality
1 Protein heterocomplex Heteromer Protein × 54 PDB declaration: 54-meric（54） Consistent with protein copy count Chain A； UniProt 1–468 Chain B； UniProt 1–468 Not recorded KH domain-containing protein 3 × 2 （Q9CWU5） NLR family, pyrin domain containing 4F × 4 （L7N1W9） NACHT, LRR and PYD domains-containing protein 5 × 4 （Q9R1M5） NACHT, LRR and PYD domains-containing protein 14 × 2 （Q6B966） Oocyte-expressed protein homolog × 4 （Q9CWE6） Inactive protein-arginine deiminase type-6 × 20 （Q8K3V4） Transducin-like enhancer protein 6 × 4 （Q9WVB3） Tubulin alpha-1A chain × 2 （P68369） Tubulin beta-4B chain × 2 （P68372） Ubiquitin-conjugating enzyme E2 D3 × 2 （P61079） E3 ubiquitin-protein ligase UHRF1 × 2 （Q8VDF2） Zinc finger BED domain-containing protein 3 × 2 （Q9D0L1） ELECTRON MICROSCOPY cryo-EM buffer：pH 7.2 cryo-EM vitrification conditions：Cryogen ETHANE-PROPANE Resolution 4.20 Å

Other States of the Same Protein in the Database

Each row is a biological assembly of the same UniProt protein in another PDB entry. The “Difference from current entry” column identifies evidence-level differences; no tag means the currently parsed fields agree.

No other PDB entry for the same UniProt protein was found.

View Construct and Data Evidence
UniProt name Q5U467_MOUSE
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–468； UniProt 1–468 Author chain B； PDBConstruct 1–468； UniProt 1–468

KH domain-containing protein 3

OrganismNot specified

UniProt Q9CWU5

State in the Current Structure

Assembly Oligomeric State Construct Mutations and Modifications Ligands, Ions and Associated Components Method and Experimental Conditions Structure Quality
1 Protein heterocomplex Heteromer Protein × 54 PDB declaration: 54-meric（54） Consistent with protein copy count Chain C； UniProt 1–440 Not recorded F-box and WD-40 domain protein 12 × 4 （Q5U467） NLR family, pyrin domain containing 4F × 4 （L7N1W9） NACHT, LRR and PYD domains-containing protein 5 × 4 （Q9R1M5） NACHT, LRR and PYD domains-containing protein 14 × 2 （Q6B966） Oocyte-expressed protein homolog × 4 （Q9CWE6） Inactive protein-arginine deiminase type-6 × 20 （Q8K3V4） Transducin-like enhancer protein 6 × 4 （Q9WVB3） Tubulin alpha-1A chain × 2 （P68369） Tubulin beta-4B chain × 2 （P68372） Ubiquitin-conjugating enzyme E2 D3 × 2 （P61079） E3 ubiquitin-protein ligase UHRF1 × 2 （Q8VDF2） Zinc finger BED domain-containing protein 3 × 2 （Q9D0L1） ELECTRON MICROSCOPY cryo-EM buffer：pH 7.2 cryo-EM vitrification conditions：Cryogen ETHANE-PROPANE Resolution 4.20 Å

Other States of the Same Protein in the Database

Each row is a biological assembly of the same UniProt protein in another PDB entry. The “Difference from current entry” column identifies evidence-level differences; no tag means the currently parsed fields agree.

Other PDB Difference from Current Entry 9SFP Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Method and Experimental Conditions Structure Quality
12DL Native structure of the cytoplasmic lattice (CPL) asymmetric unit from mouse MII eggs Deposited 2026-03-29 Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 33 PDB declaration: 33-meric
Chain LA 1–440（440 aa）
Not recorded GTP GUANOSINE-5'-TRIPHOSPHATE × 2 MG MAGNESIUM ION × 2 ZN ZINC ION × 11 CA CALCIUM ION × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.50 Å
24MC Structure of oocyte cytoplasmic lattices Deposited 2026-03-10 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 36 PDB declaration: 36-meric
Chain O 1–346（346 aa）
Not recorded ATP ADENOSINE-5'-TRIPHOSPHATE × 5 GTP GUANOSINE-5'-TRIPHOSPHATE × 4 MG MAGNESIUM ION × 4 ZN ZINC ION × 6 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.40 Å
3V69 Filia-N crystal structure Deposited 2011-12-19 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric
Chain A 1–124（124 aa） Fragment：UNP RESIDUES 1-124
Chain B 1–124（124 aa） Fragment：UNP RESIDUES 1-124
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 6.5；293 K；0.1M MES, 2.0M ammonium sulfate, pH 6.5, VAPOR DIFFUSION, temperature 293K
Resolution 2.20 Å R-free 0.273
9W2M Cryo-EM structure of the Cytoplasmic lattice(CPL) from mouse oocyte Deposited 2025-07-28 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Assembly 1 Protein heterocomplex Heteromer；Protein × 56 PDB declaration: 56-meric
Chain D 1–128（128 aa）
Chain d 1–128（128 aa）
Not recorded GDP GUANOSINE-5'-DIPHOSPHATE × 4 ADP ADENOSINE-5'-DIPHOSPHATE × 4 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.20 Å
9XRL Structure of mouse cytoplasmic lattice (CPL) repeating unit Deposited 2025-11-19 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 73 PDB declaration: 73-meric
Chain 4 1–440（440 aa）
Chain 6 1–440（440 aa）
Chain AA 1–440（440 aa）
Not recorded ZN ZINC ION × 13 GTP GUANOSINE-5'-TRIPHOSPHATE × 5 MG MAGNESIUM ION × 4 ADP ADENOSINE-5'-DIPHOSPHATE × 3 ELECTRON MICROSCOPY
cryo-EM buffer pH 6.7
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.74 Å

5 other PDB entries and 5 assemblies. Open the comparison page and filter oligomeric states

View Construct and Data Evidence
UniProt name KHDC3_MOUSE
Isoform —
PDB entities 2
Chains and sequence ranges Author chain C； PDBConstruct 1–440； UniProt 1–440

NLR family, pyrin domain containing 4F

OrganismNot specified

UniProt L7N1W9

State in the Current Structure

Assembly Oligomeric State Construct Mutations and Modifications Ligands, Ions and Associated Components Method and Experimental Conditions Structure Quality
1 Protein heterocomplex Heteromer Protein × 54 PDB declaration: 54-meric（54） Consistent with protein copy count Chain D； UniProt 1–937 Chain F； UniProt 1–937 Not recorded F-box and WD-40 domain protein 12 × 4 （Q5U467） KH domain-containing protein 3 × 2 （Q9CWU5） NACHT, LRR and PYD domains-containing protein 5 × 4 （Q9R1M5） NACHT, LRR and PYD domains-containing protein 14 × 2 （Q6B966） Oocyte-expressed protein homolog × 4 （Q9CWE6） Inactive protein-arginine deiminase type-6 × 20 （Q8K3V4） Transducin-like enhancer protein 6 × 4 （Q9WVB3） Tubulin alpha-1A chain × 2 （P68369） Tubulin beta-4B chain × 2 （P68372） Ubiquitin-conjugating enzyme E2 D3 × 2 （P61079） E3 ubiquitin-protein ligase UHRF1 × 2 （Q8VDF2） Zinc finger BED domain-containing protein 3 × 2 （Q9D0L1） ELECTRON MICROSCOPY cryo-EM buffer：pH 7.2 cryo-EM vitrification conditions：Cryogen ETHANE-PROPANE Resolution 4.20 Å

Other States of the Same Protein in the Database

Each row is a biological assembly of the same UniProt protein in another PDB entry. The “Difference from current entry” column identifies evidence-level differences; no tag means the currently parsed fields agree.

Other PDB Difference from Current Entry 9SFP Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Method and Experimental Conditions Structure Quality
12DL Native structure of the cytoplasmic lattice (CPL) asymmetric unit from mouse MII eggs Deposited 2026-03-29 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 33 PDB declaration: 33-meric
Chain MA 1–937（937 aa）
Not recorded GTP GUANOSINE-5'-TRIPHOSPHATE × 2 MG MAGNESIUM ION × 2 ZN ZINC ION × 11 CA CALCIUM ION × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.50 Å
24MC Structure of oocyte cytoplasmic lattices Deposited 2026-03-10 Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 36 PDB declaration: 36-meric
Chain M 1–937（937 aa）
Chain R 1–937（937 aa）
Not recorded ATP ADENOSINE-5'-TRIPHOSPHATE × 5 GTP GUANOSINE-5'-TRIPHOSPHATE × 4 MG MAGNESIUM ION × 4 ZN ZINC ION × 6 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.40 Å
9W2M Cryo-EM structure of the Cytoplasmic lattice(CPL) from mouse oocyte Deposited 2025-07-28 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Assembly 1 Protein heterocomplex Heteromer；Protein × 56 PDB declaration: 56-meric
Chain E 5–937（933 aa）
Chain I 5–937（933 aa）
Chain e 5–937（933 aa）
Chain i 5–937（933 aa）
Not recorded GDP GUANOSINE-5'-DIPHOSPHATE × 4 ADP ADENOSINE-5'-DIPHOSPHATE × 4 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.20 Å
9XRL Structure of mouse cytoplasmic lattice (CPL) repeating unit Deposited 2025-11-19 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 73 PDB declaration: 73-meric
Chain H 1–937（937 aa）
Chain Q 1–937（937 aa）
Chain h 1–937（937 aa）
Chain i 1–937（937 aa）
Not recorded ZN ZINC ION × 13 GTP GUANOSINE-5'-TRIPHOSPHATE × 5 MG MAGNESIUM ION × 4 ADP ADENOSINE-5'-DIPHOSPHATE × 3 ELECTRON MICROSCOPY
cryo-EM buffer pH 6.7
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.74 Å

4 other PDB entries and 4 assemblies. Open the comparison page and filter oligomeric states

View Construct and Data Evidence
UniProt name L7N1W9_MOUSE
Isoform —
PDB entities 3
Chains and sequence ranges Author chain D； PDBConstruct 1–937； UniProt 1–937 Author chain F； PDBConstruct 1–937； UniProt 1–937

NACHT, LRR and PYD domains-containing protein 5

OrganismNot specified

UniProt Q9R1M5

State in the Current Structure

Assembly Oligomeric State Construct Mutations and Modifications Ligands, Ions and Associated Components Method and Experimental Conditions Structure Quality
1 Protein heterocomplex Heteromer Protein × 54 PDB declaration: 54-meric（54） Consistent with protein copy count Chain H； UniProt 1–1163 Chain I； UniProt 1–1163 Not recorded F-box and WD-40 domain protein 12 × 4 （Q5U467） KH domain-containing protein 3 × 2 （Q9CWU5） NLR family, pyrin domain containing 4F × 4 （L7N1W9） NACHT, LRR and PYD domains-containing protein 14 × 2 （Q6B966） Oocyte-expressed protein homolog × 4 （Q9CWE6） Inactive protein-arginine deiminase type-6 × 20 （Q8K3V4） Transducin-like enhancer protein 6 × 4 （Q9WVB3） Tubulin alpha-1A chain × 2 （P68369） Tubulin beta-4B chain × 2 （P68372） Ubiquitin-conjugating enzyme E2 D3 × 2 （P61079） E3 ubiquitin-protein ligase UHRF1 × 2 （Q8VDF2） Zinc finger BED domain-containing protein 3 × 2 （Q9D0L1） ELECTRON MICROSCOPY cryo-EM buffer：pH 7.2 cryo-EM vitrification conditions：Cryogen ETHANE-PROPANE Resolution 4.20 Å

Other States of the Same Protein in the Database

Each row is a biological assembly of the same UniProt protein in another PDB entry. The “Difference from current entry” column identifies evidence-level differences; no tag means the currently parsed fields agree.

Other PDB Difference from Current Entry 9SFP Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Method and Experimental Conditions Structure Quality
12DL Native structure of the cytoplasmic lattice (CPL) asymmetric unit from mouse MII eggs Deposited 2026-03-29 Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 33 PDB declaration: 33-meric
Chain GA 1–1163（1163 aa）
Chain GB 1–1163（1163 aa）
Not recorded GTP GUANOSINE-5'-TRIPHOSPHATE × 2 MG MAGNESIUM ION × 2 ZN ZINC ION × 11 CA CALCIUM ION × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.50 Å
24MC Structure of oocyte cytoplasmic lattices Deposited 2026-03-10 Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 36 PDB declaration: 36-meric
Chain P 1–1163（1163 aa）
Chain S 1–1163（1163 aa）
Not recorded ATP ADENOSINE-5'-TRIPHOSPHATE × 5 GTP GUANOSINE-5'-TRIPHOSPHATE × 4 MG MAGNESIUM ION × 4 ZN ZINC ION × 6 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.40 Å
8H93 Structure of dimeric mouse SCMC core complex Deposited 2022-10-24 Different construct Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 6 PDB declaration: hexameric
Chain A 105–1163（1059 aa）
Chain D 105–1163（1059 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.01 Å
8H94 Structure of mouse SCMC bound with KH domain of FILIA Deposited 2022-10-24 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric
Chain A 105–1163（1059 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.90 Å
8H95 Structure of mouse SCMC bound with full-length FILIA Deposited 2022-10-24 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric
Chain A 105–1163（1059 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.38 Å
8H96 Structure of mouse SCMC core complex Deposited 2022-10-24 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric
Chain A 105–1163（1059 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.78 Å
8XI3 Structure of mouse SCMC-14-3-3gama complex Deposited 2023-12-19 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 5 PDB declaration: pentameric
Chain A 105–1163（1059 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.00 Å
9L4J Structure of mouse SCMCcore complex contain ZBED3 Deposited 2024-12-20 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric
Chain A 97–1059（963 aa）
Not recorded ZN ZINC ION × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 8；25mM Tris pH 8.0, 150mM NaCl,5 mM DTT
cryo-EM vitrification conditions Cryogen ETHANE；Vitrification carried out in argon atmosphere
Resolution 3.00 Å
9W2M Cryo-EM structure of the Cytoplasmic lattice(CPL) from mouse oocyte Deposited 2025-07-28 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Assembly 1 Protein heterocomplex Heteromer；Protein × 56 PDB declaration: 56-meric
Chain A 97–1059（963 aa）
Chain F 97–1059（963 aa）
Chain a 97–1059（963 aa）
Chain f 97–1059（963 aa）
Not recorded GDP GUANOSINE-5'-DIPHOSPHATE × 4 ADP ADENOSINE-5'-DIPHOSPHATE × 4 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.20 Å
9XRL Structure of mouse cytoplasmic lattice (CPL) repeating unit Deposited 2025-11-19 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 73 PDB declaration: 73-meric
Chain 0 105–1163（1059 aa）
Chain 2 105–1163（1059 aa）
Chain 5 105–1163（1059 aa）
Chain 7 105–1163（1059 aa）
Chain AB 105–1163（1059 aa）
Chain y 105–1163（1059 aa）
Not recorded ZN ZINC ION × 13 GTP GUANOSINE-5'-TRIPHOSPHATE × 5 MG MAGNESIUM ION × 4 ADP ADENOSINE-5'-DIPHOSPHATE × 3 ELECTRON MICROSCOPY
cryo-EM buffer pH 6.7
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.74 Å

10 other PDB entries and 10 assemblies. Open the comparison page and filter oligomeric states

View Construct and Data Evidence
UniProt name NALP5_MOUSE
Isoform —
PDB entities 4
Chains and sequence ranges Author chain H； PDBConstruct 1–1163； UniProt 1–1163 Author chain I； PDBConstruct 1–1163； UniProt 1–1163

NACHT, LRR and PYD domains-containing protein 14

OrganismNot specified

UniProt Q6B966

State in the Current Structure

Assembly Oligomeric State Construct Mutations and Modifications Ligands, Ions and Associated Components Method and Experimental Conditions Structure Quality
1 Protein heterocomplex Heteromer Protein × 54 PDB declaration: 54-meric（54） Consistent with protein copy count Chain J； UniProt 1–993 Not recorded F-box and WD-40 domain protein 12 × 4 （Q5U467） KH domain-containing protein 3 × 2 （Q9CWU5） NLR family, pyrin domain containing 4F × 4 （L7N1W9） NACHT, LRR and PYD domains-containing protein 5 × 4 （Q9R1M5） Oocyte-expressed protein homolog × 4 （Q9CWE6） Inactive protein-arginine deiminase type-6 × 20 （Q8K3V4） Transducin-like enhancer protein 6 × 4 （Q9WVB3） Tubulin alpha-1A chain × 2 （P68369） Tubulin beta-4B chain × 2 （P68372） Ubiquitin-conjugating enzyme E2 D3 × 2 （P61079） E3 ubiquitin-protein ligase UHRF1 × 2 （Q8VDF2） Zinc finger BED domain-containing protein 3 × 2 （Q9D0L1） ELECTRON MICROSCOPY cryo-EM buffer：pH 7.2 cryo-EM vitrification conditions：Cryogen ETHANE-PROPANE Resolution 4.20 Å

Other States of the Same Protein in the Database

Each row is a biological assembly of the same UniProt protein in another PDB entry. The “Difference from current entry” column identifies evidence-level differences; no tag means the currently parsed fields agree.

Other PDB Difference from Current Entry 9SFP Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Method and Experimental Conditions Structure Quality
12DL Native structure of the cytoplasmic lattice (CPL) asymmetric unit from mouse MII eggs Deposited 2026-03-29 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 33 PDB declaration: 33-meric
Chain DA 1–993（993 aa）
Chain DB 1–993（993 aa）
Not recorded GTP GUANOSINE-5'-TRIPHOSPHATE × 2 MG MAGNESIUM ION × 2 ZN ZINC ION × 11 CA CALCIUM ION × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.50 Å
24MC Structure of oocyte cytoplasmic lattices Deposited 2026-03-10 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 36 PDB declaration: 36-meric
Chain e 1–993（993 aa）
Chain f 1–993（993 aa）
Not recorded ATP ADENOSINE-5'-TRIPHOSPHATE × 5 GTP GUANOSINE-5'-TRIPHOSPHATE × 4 MG MAGNESIUM ION × 4 ZN ZINC ION × 6 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.40 Å
9W2M Cryo-EM structure of the Cytoplasmic lattice(CPL) from mouse oocyte Deposited 2025-07-28 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Assembly 1 Protein heterocomplex Heteromer；Protein × 56 PDB declaration: 56-meric
Chain N 28–993（966 aa）
Chain n 28–993（966 aa）
Not recorded GDP GUANOSINE-5'-DIPHOSPHATE × 4 ADP ADENOSINE-5'-DIPHOSPHATE × 4 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.20 Å
9WSQ Structure of dimeric mouse NLRP14-KDM2A-SKP1 complex Deposited 2025-09-15 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 6 PDB declaration: hexameric
Chain A 1–993（993 aa）
Chain D 1–993（993 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.35 Å
9WSR Structure of mouse NLRP14-KDM2A-SKP1 complex Deposited 2025-09-15 Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric
Chain A 1–993（993 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.79 Å
9XRL Structure of mouse cytoplasmic lattice (CPL) repeating unit Deposited 2025-11-19 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 73 PDB declaration: 73-meric
Chain AK 1–993（993 aa）
Chain AQ 1–993（993 aa）
Chain w 1–993（993 aa）
Not recorded ZN ZINC ION × 13 GTP GUANOSINE-5'-TRIPHOSPHATE × 5 MG MAGNESIUM ION × 4 ADP ADENOSINE-5'-DIPHOSPHATE × 3 ELECTRON MICROSCOPY
cryo-EM buffer pH 6.7
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.74 Å

6 other PDB entries and 6 assemblies. Open the comparison page and filter oligomeric states

View Construct and Data Evidence
UniProt name NAL14_MOUSE
Isoform —
PDB entities 5
Chains and sequence ranges Author chain J； PDBConstruct 1–993； UniProt 1–993

Oocyte-expressed protein homolog

OrganismNot specified

UniProt Q9CWE6

State in the Current Structure

Assembly Oligomeric State Construct Mutations and Modifications Ligands, Ions and Associated Components Method and Experimental Conditions Structure Quality
1 Protein heterocomplex Heteromer Protein × 54 PDB declaration: 54-meric（54） Consistent with protein copy count Chain K； UniProt 1–164 Chain L； UniProt 1–164 Not recorded F-box and WD-40 domain protein 12 × 4 （Q5U467） KH domain-containing protein 3 × 2 （Q9CWU5） NLR family, pyrin domain containing 4F × 4 （L7N1W9） NACHT, LRR and PYD domains-containing protein 5 × 4 （Q9R1M5） NACHT, LRR and PYD domains-containing protein 14 × 2 （Q6B966） Inactive protein-arginine deiminase type-6 × 20 （Q8K3V4） Transducin-like enhancer protein 6 × 4 （Q9WVB3） Tubulin alpha-1A chain × 2 （P68369） Tubulin beta-4B chain × 2 （P68372） Ubiquitin-conjugating enzyme E2 D3 × 2 （P61079） E3 ubiquitin-protein ligase UHRF1 × 2 （Q8VDF2） Zinc finger BED domain-containing protein 3 × 2 （Q9D0L1） ELECTRON MICROSCOPY cryo-EM buffer：pH 7.2 cryo-EM vitrification conditions：Cryogen ETHANE-PROPANE Resolution 4.20 Å

Other States of the Same Protein in the Database

Each row is a biological assembly of the same UniProt protein in another PDB entry. The “Difference from current entry” column identifies evidence-level differences; no tag means the currently parsed fields agree.

Other PDB Difference from Current Entry 9SFP Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Method and Experimental Conditions Structure Quality
12DL Native structure of the cytoplasmic lattice (CPL) asymmetric unit from mouse MII eggs Deposited 2026-03-29 Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 33 PDB declaration: 33-meric
Chain IA 1–164（164 aa）
Chain JA 1–164（164 aa）
Not recorded GTP GUANOSINE-5'-TRIPHOSPHATE × 2 MG MAGNESIUM ION × 2 ZN ZINC ION × 11 CA CALCIUM ION × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.50 Å
24MC Structure of oocyte cytoplasmic lattices Deposited 2026-03-10 Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 36 PDB declaration: 36-meric
Chain N 1–164（164 aa）
Chain U 1–164（164 aa）
Not recorded ATP ADENOSINE-5'-TRIPHOSPHATE × 5 GTP GUANOSINE-5'-TRIPHOSPHATE × 4 MG MAGNESIUM ION × 4 ZN ZINC ION × 6 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.40 Å
8H93 Structure of dimeric mouse SCMC core complex Deposited 2022-10-24 Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 6 PDB declaration: hexameric
Chain C 1–164（164 aa）
Chain F 1–164（164 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.01 Å
8H94 Structure of mouse SCMC bound with KH domain of FILIA Deposited 2022-10-24 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric
Chain C 1–164（164 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.90 Å
8H95 Structure of mouse SCMC bound with full-length FILIA Deposited 2022-10-24 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric
Chain C 1–164（164 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.38 Å
8H96 Structure of mouse SCMC core complex Deposited 2022-10-24 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric
Chain C 1–164（164 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.78 Å
8XI3 Structure of mouse SCMC-14-3-3gama complex Deposited 2023-12-19 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 5 PDB declaration: pentameric
Chain C 1–164（164 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.00 Å
9L4J Structure of mouse SCMCcore complex contain ZBED3 Deposited 2024-12-20 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric
Chain D 26–114（89 aa）
Not recorded ZN ZINC ION × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 8；25mM Tris pH 8.0, 150mM NaCl,5 mM DTT
cryo-EM vitrification conditions Cryogen ETHANE；Vitrification carried out in argon atmosphere
Resolution 3.00 Å
9W2M Cryo-EM structure of the Cytoplasmic lattice(CPL) from mouse oocyte Deposited 2025-07-28 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Assembly 1 Protein heterocomplex Heteromer；Protein × 56 PDB declaration: 56-meric
Chain C 21–145（125 aa）
Chain H 21–145（125 aa）
Chain c 21–145（125 aa）
Chain h 21–145（125 aa）
Not recorded GDP GUANOSINE-5'-DIPHOSPHATE × 4 ADP ADENOSINE-5'-DIPHOSPHATE × 4 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.20 Å
9XRL Structure of mouse cytoplasmic lattice (CPL) repeating unit Deposited 2025-11-19 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 73 PDB declaration: 73-meric
Chain AH 1–164（164 aa）
Chain AI 1–164（164 aa）
Chain AJ 1–164（164 aa）
Chain AT 1–164（164 aa）
Chain e 1–164（164 aa）
Chain g 1–164（164 aa）
Not recorded ZN ZINC ION × 13 GTP GUANOSINE-5'-TRIPHOSPHATE × 5 MG MAGNESIUM ION × 4 ADP ADENOSINE-5'-DIPHOSPHATE × 3 ELECTRON MICROSCOPY
cryo-EM buffer pH 6.7
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.74 Å

10 other PDB entries and 10 assemblies. Open the comparison page and filter oligomeric states

View Construct and Data Evidence
UniProt name OOEP_MOUSE
Isoform —
PDB entities 6
Chains and sequence ranges Author chain K； PDBConstruct 1–164； UniProt 1–164 Author chain L； PDBConstruct 1–164； UniProt 1–164

Inactive protein-arginine deiminase type-6

OrganismNot specified

UniProt Q8K3V4

State in the Current Structure

Assembly Oligomeric State Construct Mutations and Modifications Ligands, Ions and Associated Components Method and Experimental Conditions Structure Quality
1 Protein heterocomplex Heteromer Protein × 54 PDB declaration: 54-meric（54） Consistent with protein copy count Chain M； UniProt 1–682 Chain N； UniProt 1–682 Chain O； UniProt 1–682 Chain P； UniProt 1–682 Chain Q； UniProt 1–682 Chain R； UniProt 1–682 Chain S； UniProt 1–682 Chain T； UniProt 1–682 Chain U； UniProt 1–682 Chain V； UniProt 1–682 Not recorded F-box and WD-40 domain protein 12 × 4 （Q5U467） KH domain-containing protein 3 × 2 （Q9CWU5） NLR family, pyrin domain containing 4F × 4 （L7N1W9） NACHT, LRR and PYD domains-containing protein 5 × 4 （Q9R1M5） NACHT, LRR and PYD domains-containing protein 14 × 2 （Q6B966） Oocyte-expressed protein homolog × 4 （Q9CWE6） Transducin-like enhancer protein 6 × 4 （Q9WVB3） Tubulin alpha-1A chain × 2 （P68369） Tubulin beta-4B chain × 2 （P68372） Ubiquitin-conjugating enzyme E2 D3 × 2 （P61079） E3 ubiquitin-protein ligase UHRF1 × 2 （Q8VDF2） Zinc finger BED domain-containing protein 3 × 2 （Q9D0L1） ELECTRON MICROSCOPY cryo-EM buffer：pH 7.2 cryo-EM vitrification conditions：Cryogen ETHANE-PROPANE Resolution 4.20 Å

Other States of the Same Protein in the Database

Each row is a biological assembly of the same UniProt protein in another PDB entry. The “Difference from current entry” column identifies evidence-level differences; no tag means the currently parsed fields agree.

Other PDB Difference from Current Entry 9SFP Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Method and Experimental Conditions Structure Quality
12DL Native structure of the cytoplasmic lattice (CPL) asymmetric unit from mouse MII eggs Deposited 2026-03-29 Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 33 PDB declaration: 33-meric
Chain AA 1–682（682 aa）
Chain AB 1–682（682 aa）
Chain AC 1–682（682 aa）
Chain AD 1–682（682 aa）
Chain AE 1–682（682 aa）
Chain AF 1–682（682 aa）
Chain AG 1–682（682 aa）
Chain AH 1–682（682 aa）
Chain AI 1–682（682 aa）
Chain AJ 1–682（682 aa）
Not recorded GTP GUANOSINE-5'-TRIPHOSPHATE × 2 MG MAGNESIUM ION × 2 ZN ZINC ION × 11 CA CALCIUM ION × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.50 Å
24MC Structure of oocyte cytoplasmic lattices Deposited 2026-03-10 Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 36 PDB declaration: 36-meric
Chain A 1–682（682 aa）
Chain B 1–682（682 aa）
Chain C 1–682（682 aa）
Chain D 1–682（682 aa）
Chain E 1–682（682 aa）
Chain F 1–682（682 aa）
Chain G 1–682（682 aa）
Chain H 1–682（682 aa）
Chain I 1–682（682 aa）
Chain K 1–682（682 aa）
Not recorded ATP ADENOSINE-5'-TRIPHOSPHATE × 5 GTP GUANOSINE-5'-TRIPHOSPHATE × 4 MG MAGNESIUM ION × 4 ZN ZINC ION × 6 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.40 Å
9W2M Cryo-EM structure of the Cytoplasmic lattice(CPL) from mouse oocyte Deposited 2025-07-28 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Assembly 1 Protein heterocomplex Heteromer；Protein × 56 PDB declaration: 56-meric
Chain 1 1–682（682 aa）
Chain 11 1–682（682 aa）
Chain 12 1–682（682 aa）
Chain 13 1–682（682 aa）
Chain 14 1–682（682 aa）
Chain 15 1–682（682 aa）
Chain 16 1–682（682 aa）
Chain 17 1–682（682 aa）
Chain 18 1–682（682 aa）
Chain 19 1–682（682 aa）
Chain 2 1–682（682 aa）
Chain 3 1–682（682 aa）
Chain 4 1–682（682 aa）
Chain 5 1–682（682 aa）
Chain 6 1–682（682 aa）
Chain 7 1–682（682 aa）
Chain 8 1–682（682 aa）
Chain 9 1–682（682 aa）
Chain Z 1–682（682 aa）
Chain z 1–682（682 aa）
Not recorded GDP GUANOSINE-5'-DIPHOSPHATE × 4 ADP ADENOSINE-5'-DIPHOSPHATE × 4 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.20 Å
9XRL Structure of mouse cytoplasmic lattice (CPL) repeating unit Deposited 2025-11-19 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 73 PDB declaration: 73-meric
Chain B 1–682（682 aa）
Chain K 1–682（682 aa）
Chain S 1–682（682 aa）
Chain T 1–682（682 aa）
Chain U 1–682（682 aa）
Chain V 1–682（682 aa）
Chain W 1–682（682 aa）
Chain X 1–682（682 aa）
Chain Y 1–682（682 aa）
Chain Z 1–682（682 aa）
Chain b 1–682（682 aa）
Chain c 1–682（682 aa）
Chain d 1–682（682 aa）
Chain f 1–682（682 aa）
Chain j 1–682（682 aa）
Chain m 1–682（682 aa）
Chain n 1–682（682 aa）
Chain o 1–682（682 aa）
Chain r 1–682（682 aa）
Chain s 1–682（682 aa）
Not recorded ZN ZINC ION × 13 GTP GUANOSINE-5'-TRIPHOSPHATE × 5 MG MAGNESIUM ION × 4 ADP ADENOSINE-5'-DIPHOSPHATE × 3 ELECTRON MICROSCOPY
cryo-EM buffer pH 6.7
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.74 Å

4 other PDB entries and 4 assemblies. Open the comparison page and filter oligomeric states

View Construct and Data Evidence
UniProt name PADI6_MOUSE
Isoform —
PDB entities 7
Chains and sequence ranges Author chain M； PDBConstruct 1–682； UniProt 1–682 Author chain N； PDBConstruct 1–682； UniProt 1–682 Author chain O； PDBConstruct 1–682； UniProt 1–682 Author chain P； PDBConstruct 1–682； UniProt 1–682 Author chain Q； PDBConstruct 1–682； UniProt 1–682 Author chain R； PDBConstruct 1–682； UniProt 1–682 Author chain S； PDBConstruct 1–682； UniProt 1–682 Author chain T； PDBConstruct 1–682； UniProt 1–682 Author chain U； PDBConstruct 1–682； UniProt 1–682 Author chain V； PDBConstruct 1–682； UniProt 1–682

Transducin-like enhancer protein 6

OrganismNot specified

UniProt Q9WVB3

State in the Current Structure

Assembly Oligomeric State Construct Mutations and Modifications Ligands, Ions and Associated Components Method and Experimental Conditions Structure Quality
1 Protein heterocomplex Heteromer Protein × 54 PDB declaration: 54-meric（54） Consistent with protein copy count Chain W； UniProt 1–581 Chain Y； UniProt 1–581 Not recorded F-box and WD-40 domain protein 12 × 4 （Q5U467） KH domain-containing protein 3 × 2 （Q9CWU5） NLR family, pyrin domain containing 4F × 4 （L7N1W9） NACHT, LRR and PYD domains-containing protein 5 × 4 （Q9R1M5） NACHT, LRR and PYD domains-containing protein 14 × 2 （Q6B966） Oocyte-expressed protein homolog × 4 （Q9CWE6） Inactive protein-arginine deiminase type-6 × 20 （Q8K3V4） Tubulin alpha-1A chain × 2 （P68369） Tubulin beta-4B chain × 2 （P68372） Ubiquitin-conjugating enzyme E2 D3 × 2 （P61079） E3 ubiquitin-protein ligase UHRF1 × 2 （Q8VDF2） Zinc finger BED domain-containing protein 3 × 2 （Q9D0L1） ELECTRON MICROSCOPY cryo-EM buffer：pH 7.2 cryo-EM vitrification conditions：Cryogen ETHANE-PROPANE Resolution 4.20 Å

Other States of the Same Protein in the Database

Each row is a biological assembly of the same UniProt protein in another PDB entry. The “Difference from current entry” column identifies evidence-level differences; no tag means the currently parsed fields agree.

Other PDB Difference from Current Entry 9SFP Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Method and Experimental Conditions Structure Quality
12DL Native structure of the cytoplasmic lattice (CPL) asymmetric unit from mouse MII eggs Deposited 2026-03-29 Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 33 PDB declaration: 33-meric
Chain HA 1–581（581 aa）
Chain HB 1–581（581 aa）
Not recorded GTP GUANOSINE-5'-TRIPHOSPHATE × 2 MG MAGNESIUM ION × 2 ZN ZINC ION × 11 CA CALCIUM ION × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.50 Å
24MC Structure of oocyte cytoplasmic lattices Deposited 2026-03-10 Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 36 PDB declaration: 36-meric
Chain Q 1–581（581 aa）
Chain T 1–581（581 aa）
Not recorded ATP ADENOSINE-5'-TRIPHOSPHATE × 5 GTP GUANOSINE-5'-TRIPHOSPHATE × 4 MG MAGNESIUM ION × 4 ZN ZINC ION × 6 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.40 Å
8H93 Structure of dimeric mouse SCMC core complex Deposited 2022-10-24 Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 6 PDB declaration: hexameric
Chain B 1–581（581 aa）
Chain E 1–581（581 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.01 Å
8H94 Structure of mouse SCMC bound with KH domain of FILIA Deposited 2022-10-24 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric
Chain B 1–581（581 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.90 Å
8H95 Structure of mouse SCMC bound with full-length FILIA Deposited 2022-10-24 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric
Chain B 1–581（581 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.38 Å
8H96 Structure of mouse SCMC core complex Deposited 2022-10-24 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric
Chain B 1–581（581 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.78 Å
8XI3 Structure of mouse SCMC-14-3-3gama complex Deposited 2023-12-19 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 5 PDB declaration: pentameric
Chain B 48–581（534 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.00 Å
9L4J Structure of mouse SCMCcore complex contain ZBED3 Deposited 2024-12-20 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric
Chain B 155–581（427 aa）
Not recorded ZN ZINC ION × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 8；25mM Tris pH 8.0, 150mM NaCl,5 mM DTT
cryo-EM vitrification conditions Cryogen ETHANE；Vitrification carried out in argon atmosphere
Resolution 3.00 Å
9W2M Cryo-EM structure of the Cytoplasmic lattice(CPL) from mouse oocyte Deposited 2025-07-28 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Assembly 1 Protein heterocomplex Heteromer；Protein × 56 PDB declaration: 56-meric
Chain B 146–581（436 aa）
Chain G 146–581（436 aa）
Chain b 146–581（436 aa）
Chain g 146–581（436 aa）
Not recorded GDP GUANOSINE-5'-DIPHOSPHATE × 4 ADP ADENOSINE-5'-DIPHOSPHATE × 4 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.20 Å
9XRL Structure of mouse cytoplasmic lattice (CPL) repeating unit Deposited 2025-11-19 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 73 PDB declaration: 73-meric
Chain 8 1–581（581 aa）
Chain AC 1–581（581 aa）
Chain E 1–581（581 aa）
Chain I 1–581（581 aa）
Chain P 1–581（581 aa）
Chain z 1–581（581 aa）
Not recorded ZN ZINC ION × 13 GTP GUANOSINE-5'-TRIPHOSPHATE × 5 MG MAGNESIUM ION × 4 ADP ADENOSINE-5'-DIPHOSPHATE × 3 ELECTRON MICROSCOPY
cryo-EM buffer pH 6.7
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.74 Å

10 other PDB entries and 10 assemblies. Open the comparison page and filter oligomeric states

View Construct and Data Evidence
UniProt name TLE6_MOUSE
Isoform —
PDB entities 8
Chains and sequence ranges Author chain W； PDBConstruct 1–581； UniProt 1–581 Author chain Y； PDBConstruct 1–581； UniProt 1–581

Tubulin alpha-1A chain

OrganismNot specified

UniProt P68369

State in the Current Structure

Assembly Oligomeric State Construct Mutations and Modifications Ligands, Ions and Associated Components Method and Experimental Conditions Structure Quality
1 Protein heterocomplex Heteromer Protein × 54 PDB declaration: 54-meric（54） Consistent with protein copy count Chain a； UniProt 1–451 Not recorded F-box and WD-40 domain protein 12 × 4 （Q5U467） KH domain-containing protein 3 × 2 （Q9CWU5） NLR family, pyrin domain containing 4F × 4 （L7N1W9） NACHT, LRR and PYD domains-containing protein 5 × 4 （Q9R1M5） NACHT, LRR and PYD domains-containing protein 14 × 2 （Q6B966） Oocyte-expressed protein homolog × 4 （Q9CWE6） Inactive protein-arginine deiminase type-6 × 20 （Q8K3V4） Transducin-like enhancer protein 6 × 4 （Q9WVB3） Tubulin beta-4B chain × 2 （P68372） Ubiquitin-conjugating enzyme E2 D3 × 2 （P61079） E3 ubiquitin-protein ligase UHRF1 × 2 （Q8VDF2） Zinc finger BED domain-containing protein 3 × 2 （Q9D0L1） ELECTRON MICROSCOPY cryo-EM buffer：pH 7.2 cryo-EM vitrification conditions：Cryogen ETHANE-PROPANE Resolution 4.20 Å

Other States of the Same Protein in the Database

Each row is a biological assembly of the same UniProt protein in another PDB entry. The “Difference from current entry” column identifies evidence-level differences; no tag means the currently parsed fields agree.

Other PDB Difference from Current Entry 9SFP Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Method and Experimental Conditions Structure Quality
8IXA GMPCPP-Alpha1A/Beta2A-microtubule decorated with kinesin non-seam region Deposited 2023-03-31 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Assembly 1 Protein heterocomplex Heteromer；Protein × 27 PDB declaration: 27-meric
Chain A 1–451（451 aa）
Chain B 1–451（451 aa）
Chain C 1–451（451 aa）
Chain D 1–451（451 aa）
Chain E 1–451（451 aa）
Chain F 1–451（451 aa）
Chain G 1–451（451 aa）
Chain H 1–451（451 aa）
Chain I 1–451（451 aa）
Not recorded GTP GUANOSINE-5'-TRIPHOSPHATE × 9 G2P PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER × 9 ATP ADENOSINE-5'-TRIPHOSPHATE × 9 ELECTRON MICROSCOPY
cryo-EM buffer pH 6.9
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.20 Å
8IXB GMPCPP-Alpha1A/Beta2A-microtubule decorated with kinesin seam region Deposited 2023-03-31 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Assembly 1 Protein heterocomplex Heteromer；Protein × 12 PDB declaration: dodecameric
Chain A 1–451（451 aa）
Chain E 1–451（451 aa）
Chain F 1–451（451 aa）
Chain H 1–451（451 aa）
Not recorded GTP GUANOSINE-5'-TRIPHOSPHATE × 4 G2P PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER × 4 ATP ADENOSINE-5'-TRIPHOSPHATE × 4 ELECTRON MICROSCOPY
cryo-EM buffer pH 6.9
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.20 Å
8TO0 48-nm repeating structure of doublets from mouse sperm flagella Deposited 2023-08-02 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 471 PDB declaration: 471-meric
Chain A5 1–451（451 aa）
Chain A7 1–451（451 aa）
Chain A9 1–451（451 aa）
Chain AM 1–451（451 aa）
Chain AO 1–451（451 aa）
Chain AQ 1–451（451 aa）
Chain AS 1–451（451 aa）
Chain AU 1–451（451 aa）
Chain AW 1–451（451 aa）
Chain AY 1–451（451 aa）
Chain Aj 1–451（451 aa）
Chain Al 1–451（451 aa）
Chain An 1–451（451 aa）
Chain Ap 1–451（451 aa）
Chain Ar 1–451（451 aa）
Chain At 1–451（451 aa）
Chain Av 1–451（451 aa）
Chain B0 1–451（451 aa）
Chain B2 1–451（451 aa）
Chain B4 1–451（451 aa）
Chain B8 1–451（451 aa）
Chain BA 1–451（451 aa）
Chain BC 1–451（451 aa）
Chain BE 1–451（451 aa）
Chain BO 1–451（451 aa）
Chain BQ 1–451（451 aa）
Chain BS 1–451（451 aa）
Chain BU 1–451（451 aa）
Chain BW 1–451（451 aa）
Chain BY 1–451（451 aa）
Chain Bc 1–451（451 aa）
Chain Be 1–451（451 aa）
Chain Bg 1–451（451 aa）
Chain Bi 1–451（451 aa）
Chain Bk 1–451（451 aa）
Chain Bm 1–451（451 aa）
Chain Br 1–451（451 aa）
Chain Bt 1–451（451 aa）
Chain Bv 1–451（451 aa）
Chain Bx 1–451（451 aa）
Chain Bz 1–451（451 aa）
Chain C0 1–451（451 aa）
Chain C1 1–451（451 aa）
Chain C3 1–451（451 aa）
Chain C8 1–451（451 aa）
Chain CB 1–451（451 aa）
Chain CD 1–451（451 aa）
Chain CF 1–451（451 aa）
Chain CH 1–451（451 aa）
Chain CJ 1–451（451 aa）
Chain CN 1–451（451 aa）
Chain CP 1–451（451 aa）
Chain CR 1–451（451 aa）
Chain CT 1–451（451 aa）
Chain CV 1–451（451 aa）
Chain CX 1–451（451 aa）
Chain Cc 1–451（451 aa）
Chain Ce 1–451（451 aa）
Chain Cg 1–451（451 aa）
Chain Ci 1–451（451 aa）
Chain Ck 1–451（451 aa）
Chain Cm 1–451（451 aa）
Chain Co 1–451（451 aa）
Chain Cs 1–451（451 aa）
Chain Cu 1–451（451 aa）
Chain Cw 1–451（451 aa）
Chain Cy 1–451（451 aa）
Chain D2 1–451（451 aa）
Chain D5 1–451（451 aa）
Chain D7 1–451（451 aa）
Chain D9 1–451（451 aa）
Chain DB 1–451（451 aa）
Chain DD 1–451（451 aa）
Chain DF 1–451（451 aa）
Chain DH 1–451（451 aa）
Chain DM 1–451（451 aa）
Chain DO 1–451（451 aa）
Chain DQ 1–451（451 aa）
Chain DS 1–451（451 aa）
Chain DU 1–451（451 aa）
Chain DW 1–451（451 aa）
Chain Db 1–451（451 aa）
Chain Dd 1–451（451 aa）
Chain Df 1–451（451 aa）
Chain Dh 1–451（451 aa）
Chain Dj 1–451（451 aa）
Chain Dl 1–451（451 aa）
Chain Dp 1–451（451 aa）
Chain Dr 1–451（451 aa）
Chain Dt 1–451（451 aa）
Chain Dv 1–451（451 aa）
Chain Dx 1–451（451 aa）
Chain Dz 1–451（451 aa）
Chain E3 1–451（451 aa）
Chain E5 1–451（451 aa）
Chain E7 1–451（451 aa）
Chain E9 1–451（451 aa）
Chain EA 1–451（451 aa）
Chain EC 1–451（451 aa）
Chain EE 1–451（451 aa）
Chain EG 1–451（451 aa）
Chain EJ 1–451（451 aa）
Chain EL 1–451（451 aa）
Chain EN 1–451（451 aa）
Chain EP 1–451（451 aa）
Chain ER 1–451（451 aa）
Chain ET 1–451（451 aa）
Chain EV 1–451（451 aa）
Chain EY 1–451（451 aa）
Chain Ea 1–451（451 aa）
Chain Ec 1–451（451 aa）
Chain Ee 1–451（451 aa）
Chain Eg 1–451（451 aa）
Chain Ei 1–451（451 aa）
Chain Ek 1–451（451 aa）
Chain Eo 1–451（451 aa）
Chain Eq 1–451（451 aa）
Chain Es 1–451（451 aa）
Chain Eu 1–451（451 aa）
Chain Ew 1–451（451 aa）
Chain Ey 1–451（451 aa）
Chain FA 1–451（451 aa）
Chain FC 1–451（451 aa）
Chain FG 1–451（451 aa）
Chain FI 1–451（451 aa）
Chain FK 1–451（451 aa）
Chain FM 1–451（451 aa）
Chain FO 1–451（451 aa）
Chain FQ 1–451（451 aa）
Chain FU 1–451（451 aa）
Chain FW 1–451（451 aa）
Chain FY 1–451（451 aa）
Chain Fa 1–451（451 aa）
Chain Fc 1–451（451 aa）
Chain Fe 1–451（451 aa）
Chain N 1–451（451 aa）
Chain P 1–451（451 aa）
Chain R 1–451（451 aa）
Chain T 1–451（451 aa）
Chain V 1–451（451 aa）
Chain X 1–451（451 aa）
Chain Z 1–451（451 aa）
Chain n 1–451（451 aa）
Chain p 1–451（451 aa）
Chain r 1–451（451 aa）
Chain t 1–451（451 aa）
Chain v 1–451（451 aa）
Chain x 1–451（451 aa）
Chain z 1–451（451 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 7.70 Å
9PND In situ microtubule of EpoB-induced regenerating axons Deposited 2025-07-20 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric
Chain A 1–451（451 aa）
Chain C 1–451（451 aa）
Not recorded MG MAGNESIUM ION × 4 GDP GUANOSINE-5'-DIPHOSPHATE × 2 EPB 7,11-DIHYDROXY-8,8,10,12,16-PENTAMETHYL-3-[1-METHYL-2-(2-METHYL-THIAZOL-4-YL)VINYL]-4,17-DIOXABICYCLO[14.1.0]HEPTADECANE-5,9-DIONE × 2 GTP GUANOSINE-5'-TRIPHOSPHATE × 2 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.2；Gibco Neurobasal Media
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.19 Å
9XRL Structure of mouse cytoplasmic lattice (CPL) repeating unit Deposited 2025-11-19 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 73 PDB declaration: 73-meric
Chain AF 1–451（451 aa）
Chain AO 1–451（451 aa）
Chain u 1–451（451 aa）
Not recorded ZN ZINC ION × 13 GTP GUANOSINE-5'-TRIPHOSPHATE × 5 MG MAGNESIUM ION × 4 ADP ADENOSINE-5'-DIPHOSPHATE × 3 ELECTRON MICROSCOPY
cryo-EM buffer pH 6.7
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.74 Å

5 other PDB entries and 5 assemblies. Open the comparison page and filter oligomeric states

View Construct and Data Evidence
UniProt name TBA1A_MOUSE
Isoform —
PDB entities 9
Chains and sequence ranges Author chain a； PDBConstruct 1–451； UniProt 1–451

Tubulin beta-4B chain

OrganismNot specified

UniProt P68372

State in the Current Structure

Assembly Oligomeric State Construct Mutations and Modifications Ligands, Ions and Associated Components Method and Experimental Conditions Structure Quality
1 Protein heterocomplex Heteromer Protein × 54 PDB declaration: 54-meric（54） Consistent with protein copy count Chain b； UniProt 1–445 Not recorded F-box and WD-40 domain protein 12 × 4 （Q5U467） KH domain-containing protein 3 × 2 （Q9CWU5） NLR family, pyrin domain containing 4F × 4 （L7N1W9） NACHT, LRR and PYD domains-containing protein 5 × 4 （Q9R1M5） NACHT, LRR and PYD domains-containing protein 14 × 2 （Q6B966） Oocyte-expressed protein homolog × 4 （Q9CWE6） Inactive protein-arginine deiminase type-6 × 20 （Q8K3V4） Transducin-like enhancer protein 6 × 4 （Q9WVB3） Tubulin alpha-1A chain × 2 （P68369） Ubiquitin-conjugating enzyme E2 D3 × 2 （P61079） E3 ubiquitin-protein ligase UHRF1 × 2 （Q8VDF2） Zinc finger BED domain-containing protein 3 × 2 （Q9D0L1） ELECTRON MICROSCOPY cryo-EM buffer：pH 7.2 cryo-EM vitrification conditions：Cryogen ETHANE-PROPANE Resolution 4.20 Å

Other States of the Same Protein in the Database

Each row is a biological assembly of the same UniProt protein in another PDB entry. The “Difference from current entry” column identifies evidence-level differences; no tag means the currently parsed fields agree.

Other PDB Difference from Current Entry 9SFP Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Method and Experimental Conditions Structure Quality
12DL Native structure of the cytoplasmic lattice (CPL) asymmetric unit from mouse MII eggs Deposited 2026-03-29 Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 33 PDB declaration: 33-meric
Chain FA 1–445（445 aa）
Not recorded GTP GUANOSINE-5'-TRIPHOSPHATE × 2 MG MAGNESIUM ION × 2 ZN ZINC ION × 11 CA CALCIUM ION × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.50 Å
8I7O In situ structure of axonemal doublet microtubules in mouse sperm with 16-nm repeat Deposited 2023-02-01 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 189 PDB declaration: 189-meric
Chain AF 1–427（427 aa）
Chain AH 1–427（427 aa）
Chain BF 1–427（427 aa）
Chain BH 1–427（427 aa）
Chain CF 1–427（427 aa）
Chain CH 1–427（427 aa）
Chain CJ 1–427（427 aa）
Chain DD 1–427（427 aa）
Chain DF 1–427（427 aa）
Chain DH 1–427（427 aa）
Chain ED 1–427（427 aa）
Chain EF 1–427（427 aa）
Chain EH 1–427（427 aa）
Chain FD 1–427（427 aa）
Chain FF 1–427（427 aa）
Chain FH 1–427（427 aa）
Chain GD 1–427（427 aa）
Chain GF 1–427（427 aa）
Chain GH 1–427（427 aa）
Chain HD 1–427（427 aa）
Chain HF 1–427（427 aa）
Chain HH 1–427（427 aa）
Chain IF 1–427（427 aa）
Chain IH 1–427（427 aa）
Chain JD 1–427（427 aa）
Chain JF 1–427（427 aa）
Chain JH 1–427（427 aa）
Chain KD 1–427（427 aa）
Chain KF 1–427（427 aa）
Chain KH 1–427（427 aa）
Chain LD 1–427（427 aa）
Chain LF 1–427（427 aa）
Chain LH 1–427（427 aa）
Chain MF 1–427（427 aa）
Chain MH 1–427（427 aa）
Chain ND 1–427（427 aa）
Chain NF 1–427（427 aa）
Chain NH 1–427（427 aa）
Chain OD 1–427（427 aa）
Chain OF 1–427（427 aa）
Chain OH 1–427（427 aa）
Chain PF 1–427（427 aa）
Chain PH 1–427（427 aa）
Chain QF 1–427（427 aa）
Chain QH 1–427（427 aa）
Chain RF 1–427（427 aa）
Chain RH 1–427（427 aa）
Chain RJ 1–427（427 aa）
Chain SF 1–427（427 aa）
Chain SH 1–427（427 aa）
Chain SJ 1–427（427 aa）
Chain TF 1–427（427 aa）
Chain TH 1–427（427 aa）
Chain TJ 1–427（427 aa）
Chain UD 1–427（427 aa）
Chain UF 1–427（427 aa）
Chain UH 1–427（427 aa）
Chain VD 1–427（427 aa）
Chain VF 1–427（427 aa）
Chain VH 1–427（427 aa）
Chain WF 1–427（427 aa）
Chain WH 1–427（427 aa）
Not recorded GTP GUANOSINE-5'-TRIPHOSPHATE × 123 ELECTRON MICROSCOPY
cryo-EM buffer pH 7
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.50 Å
8I7R In situ structure of axonemal doublet microtubules in mouse sperm with 48-nm repeat Deposited 2023-02-02 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 450 PDB declaration: 450-meric
Chain AB 1–427（427 aa）
Chain AD 1–427（427 aa）
Chain AF 1–427（427 aa）
Chain AH 1–427（427 aa）
Chain AJ 1–427（427 aa）
Chain AL 1–427（427 aa）
Chain BB 1–427（427 aa）
Chain BD 1–427（427 aa）
Chain BF 1–427（427 aa）
Chain BH 1–427（427 aa）
Chain BJ 1–427（427 aa）
Chain BL 1–427（427 aa）
Chain CB 1–427（427 aa）
Chain CD 1–427（427 aa）
Chain CF 1–427（427 aa）
Chain CH 1–427（427 aa）
Chain CJ 1–427（427 aa）
Chain CL 1–427（427 aa）
Chain DB 1–427（427 aa）
Chain DD 1–427（427 aa）
Chain DF 1–427（427 aa）
Chain DH 1–427（427 aa）
Chain DJ 1–427（427 aa）
Chain DL 1–427（427 aa）
Chain EB 1–427（427 aa）
Chain ED 1–427（427 aa）
Chain EF 1–427（427 aa）
Chain EH 1–427（427 aa）
Chain EJ 1–427（427 aa）
Chain EL 1–427（427 aa）
Chain FB 1–427（427 aa）
Chain FD 1–427（427 aa）
Chain FF 1–427（427 aa）
Chain FH 1–427（427 aa）
Chain FJ 1–427（427 aa）
Chain FL 1–427（427 aa）
Chain GB 1–427（427 aa）
Chain GD 1–427（427 aa）
Chain GF 1–427（427 aa）
Chain GH 1–427（427 aa）
Chain GJ 1–427（427 aa）
Chain GL 1–427（427 aa）
Chain HB 1–427（427 aa）
Chain HD 1–427（427 aa）
Chain HF 1–427（427 aa）
Chain HH 1–427（427 aa）
Chain HJ 1–427（427 aa）
Chain HL 1–427（427 aa）
Chain IB 1–427（427 aa）
Chain ID 1–427（427 aa）
Chain IF 1–427（427 aa）
Chain IH 1–427（427 aa）
Chain IJ 1–427（427 aa）
Chain IL 1–427（427 aa）
Chain JB 1–427（427 aa）
Chain JD 1–427（427 aa）
Chain JF 1–427（427 aa）
Chain JH 1–427（427 aa）
Chain JJ 1–427（427 aa）
Chain JL 1–427（427 aa）
Chain KB 1–427（427 aa）
Chain KD 1–427（427 aa）
Chain KF 1–427（427 aa）
Chain KH 1–427（427 aa）
Chain KJ 1–427（427 aa）
Chain KL 1–427（427 aa）
Chain LB 1–427（427 aa）
Chain LD 1–427（427 aa）
Chain LF 1–427（427 aa）
Chain LH 1–427（427 aa）
Chain LJ 1–427（427 aa）
Chain LL 1–427（427 aa）
Chain MB 1–427（427 aa）
Chain MD 1–427（427 aa）
Chain MF 1–427（427 aa）
Chain MH 1–427（427 aa）
Chain MJ 1–427（427 aa）
Chain ML 1–427（427 aa）
Chain NB 1–427（427 aa）
Chain ND 1–427（427 aa）
Chain NF 1–427（427 aa）
Chain NH 1–427（427 aa）
Chain NJ 1–427（427 aa）
Chain NL 1–427（427 aa）
Chain OB 1–427（427 aa）
Chain OD 1–427（427 aa）
Chain OF 1–427（427 aa）
Chain OH 1–427（427 aa）
Chain OJ 1–427（427 aa）
Chain OL 1–427（427 aa）
Chain PB 1–427（427 aa）
Chain PD 1–427（427 aa）
Chain PF 1–427（427 aa）
Chain PH 1–427（427 aa）
Chain PJ 1–427（427 aa）
Chain PL 1–427（427 aa）
Chain QB 1–427（427 aa）
Chain QD 1–427（427 aa）
Chain QF 1–427（427 aa）
Chain QH 1–427（427 aa）
Chain QJ 1–427（427 aa）
Chain QL 1–427（427 aa）
Chain RB 1–427（427 aa）
Chain RD 1–427（427 aa）
Chain RF 1–427（427 aa）
Chain RH 1–427（427 aa）
Chain RJ 1–427（427 aa）
Chain RL 1–427（427 aa）
Chain SB 1–427（427 aa）
Chain SD 1–427（427 aa）
Chain SF 1–427（427 aa）
Chain SH 1–427（427 aa）
Chain SJ 1–427（427 aa）
Chain SL 1–427（427 aa）
Chain TB 1–427（427 aa）
Chain TD 1–427（427 aa）
Chain TF 1–427（427 aa）
Chain TH 1–427（427 aa）
Chain TJ 1–427（427 aa）
Chain TL 1–427（427 aa）
Chain TN 1–427（427 aa）
Chain UB 1–427（427 aa）
Chain UD 1–427（427 aa）
Chain UF 1–427（427 aa）
Chain UH 1–427（427 aa）
Chain UJ 1–427（427 aa）
Chain UL 1–427（427 aa）
Chain VB 1–427（427 aa）
Chain VD 1–427（427 aa）
Chain VF 1–427（427 aa）
Chain VH 1–427（427 aa）
Chain VJ 1–427（427 aa）
Chain VL 1–427（427 aa）
Chain WB 1–427（427 aa）
Chain WD 1–427（427 aa）
Chain WF 1–427（427 aa）
Chain WH 1–427（427 aa）
Chain WJ 1–427（427 aa）
Chain WL 1–427（427 aa）
Not recorded GTP GUANOSINE-5'-TRIPHOSPHATE × 279 ELECTRON MICROSCOPY
cryo-EM buffer pH 7
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 6.50 Å
8IYJ Cryo-EM structure of the 48-nm repeat doublet microtubule from mouse sperm Deposited 2023-04-05 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 576 PDB declaration: 576-meric
Chain AB 1–445（445 aa）
Chain AD 1–445（445 aa）
Chain AF 1–445（445 aa）
Chain AH 1–445（445 aa）
Chain AJ 1–445（445 aa）
Chain AL 1–445（445 aa）
Chain AN 1–445（445 aa）
Chain AP 1–445（445 aa）
Chain BB 1–445（445 aa）
Chain BD 1–445（445 aa）
Chain BF 1–445（445 aa）
Chain BH 1–445（445 aa）
Chain BJ 1–445（445 aa）
Chain BL 1–445（445 aa）
Chain BN 1–445（445 aa）
Chain BP 1–445（445 aa）
Chain CB 1–445（445 aa）
Chain CD 1–445（445 aa）
Chain CF 1–445（445 aa）
Chain CH 1–445（445 aa）
Chain CJ 1–445（445 aa）
Chain CL 1–445（445 aa）
Chain CN 1–445（445 aa）
Chain CP 1–445（445 aa）
Chain DB 1–445（445 aa）
Chain DD 1–445（445 aa）
Chain DF 1–445（445 aa）
Chain DH 1–445（445 aa）
Chain DJ 1–445（445 aa）
Chain DL 1–445（445 aa）
Chain DN 1–445（445 aa）
Chain DP 1–445（445 aa）
Chain EB 1–445（445 aa）
Chain ED 1–445（445 aa）
Chain EF 1–445（445 aa）
Chain EH 1–445（445 aa）
Chain EJ 1–445（445 aa）
Chain EL 1–445（445 aa）
Chain EN 1–445（445 aa）
Chain FB 1–445（445 aa）
Chain FD 1–445（445 aa）
Chain FF 1–445（445 aa）
Chain FH 1–445（445 aa）
Chain FJ 1–445（445 aa）
Chain FL 1–445（445 aa）
Chain FN 1–445（445 aa）
Chain GB 1–445（445 aa）
Chain GD 1–445（445 aa）
Chain GF 1–445（445 aa）
Chain GH 1–445（445 aa）
Chain GJ 1–445（445 aa）
Chain GL 1–445（445 aa）
Chain GN 1–445（445 aa）
Chain HB 1–445（445 aa）
Chain HD 1–445（445 aa）
Chain HF 1–445（445 aa）
Chain HH 1–445（445 aa）
Chain HJ 1–445（445 aa）
Chain HL 1–445（445 aa）
Chain HN 1–445（445 aa）
Chain HP 1–445（445 aa）
Chain IB 1–445（445 aa）
Chain ID 1–445（445 aa）
Chain IF 1–445（445 aa）
Chain IH 1–445（445 aa）
Chain IJ 1–445（445 aa）
Chain IL 1–445（445 aa）
Chain IN 1–445（445 aa）
Chain IP 1–445（445 aa）
Chain JB 1–445（445 aa）
Chain JD 1–445（445 aa）
Chain JF 1–445（445 aa）
Chain JH 1–445（445 aa）
Chain JJ 1–445（445 aa）
Chain JL 1–445（445 aa）
Chain JN 1–445（445 aa）
Chain JP 1–445（445 aa）
Chain KB 1–445（445 aa）
Chain KD 1–445（445 aa）
Chain KF 1–445（445 aa）
Chain KH 1–445（445 aa）
Chain KJ 1–445（445 aa）
Chain KL 1–445（445 aa）
Chain KN 1–445（445 aa）
Chain KP 1–445（445 aa）
Chain LB 1–445（445 aa）
Chain LD 1–445（445 aa）
Chain LF 1–445（445 aa）
Chain LH 1–445（445 aa）
Chain LJ 1–445（445 aa）
Chain LL 1–445（445 aa）
Chain LN 1–445（445 aa）
Chain LP 1–445（445 aa）
Chain MB 1–445（445 aa）
Chain MD 1–445（445 aa）
Chain MF 1–445（445 aa）
Chain MH 1–445（445 aa）
Chain MJ 1–445（445 aa）
Chain ML 1–445（445 aa）
Chain MN 1–445（445 aa）
Chain MP 1–445（445 aa）
Chain NB 1–445（445 aa）
Chain ND 1–445（445 aa）
Chain NF 1–445（445 aa）
Chain NH 1–445（445 aa）
Chain NJ 1–445（445 aa）
Chain NL 1–445（445 aa）
Chain NN 1–445（445 aa）
Chain NP 1–445（445 aa）
Chain OB 1–445（445 aa）
Chain OD 1–445（445 aa）
Chain OF 1–445（445 aa）
Chain OH 1–445（445 aa）
Chain OJ 1–445（445 aa）
Chain OL 1–445（445 aa）
Chain ON 1–445（445 aa）
Chain OP 1–445（445 aa）
Chain PB 1–445（445 aa）
Chain PD 1–445（445 aa）
Chain PF 1–445（445 aa）
Chain PH 1–445（445 aa）
Chain PJ 1–445（445 aa）
Chain PL 1–445（445 aa）
Chain PN 1–445（445 aa）
Chain PP 1–445（445 aa）
Chain QB 1–445（445 aa）
Chain QD 1–445（445 aa）
Chain QF 1–445（445 aa）
Chain QH 1–445（445 aa）
Chain QJ 1–445（445 aa）
Chain QL 1–445（445 aa）
Chain QN 1–445（445 aa）
Chain QP 1–445（445 aa）
Chain RD 1–445（445 aa）
Chain RF 1–445（445 aa）
Chain RH 1–445（445 aa）
Chain RJ 1–445（445 aa）
Chain RL 1–445（445 aa）
Chain RN 1–445（445 aa）
Chain RP 1–445（445 aa）
Chain SB 1–445（445 aa）
Chain SD 1–445（445 aa）
Chain SF 1–445（445 aa）
Chain SH 1–445（445 aa）
Chain SJ 1–445（445 aa）
Chain SL 1–445（445 aa）
Chain SN 1–445（445 aa）
Chain TB 1–445（445 aa）
Chain TD 1–445（445 aa）
Chain TF 1–445（445 aa）
Chain TH 1–445（445 aa）
Chain TJ 1–445（445 aa）
Chain TL 1–445（445 aa）
Chain TN 1–445（445 aa）
Chain UB 1–445（445 aa）
Chain UD 1–445（445 aa）
Chain UF 1–445（445 aa）
Chain UH 1–445（445 aa）
Chain UJ 1–445（445 aa）
Chain UL 1–445（445 aa）
Chain UN 1–445（445 aa）
Chain VB 1–445（445 aa）
Chain VD 1–445（445 aa）
Chain VF 1–445（445 aa）
Chain VH 1–445（445 aa）
Chain VJ 1–445（445 aa）
Chain VL 1–445（445 aa）
Chain VN 1–445（445 aa）
Chain WB 1–445（445 aa）
Chain WD 1–445（445 aa）
Chain WF 1–445（445 aa）
Chain WH 1–445（445 aa）
Chain WJ 1–445（445 aa）
Chain WL 1–445（445 aa）
Chain WN 1–445（445 aa）
Chain WP 1–445（445 aa）
Not recorded GTP GUANOSINE-5'-TRIPHOSPHATE × 178 MG MAGNESIUM ION × 178 GDP GUANOSINE-5'-DIPHOSPHATE × 176 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.50 Å
8TO0 48-nm repeating structure of doublets from mouse sperm flagella Deposited 2023-08-02 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 471 PDB declaration: 471-meric
Chain A0 1–445（445 aa）
Chain A4 1–445（445 aa）
Chain A6 1–445（445 aa）
Chain A8 1–445（445 aa）
Chain AN 1–445（445 aa）
Chain AP 1–445（445 aa）
Chain AR 1–445（445 aa）
Chain AT 1–445（445 aa）
Chain AV 1–445（445 aa）
Chain AX 1–445（445 aa）
Chain Ak 1–445（445 aa）
Chain Am 1–445（445 aa）
Chain Ao 1–445（445 aa）
Chain Aq 1–445（445 aa）
Chain As 1–445（445 aa）
Chain Au 1–445（445 aa）
Chain Aw 1–445（445 aa）
Chain B1 1–445（445 aa）
Chain B3 1–445（445 aa）
Chain B7 1–445（445 aa）
Chain B9 1–445（445 aa）
Chain BB 1–445（445 aa）
Chain BD 1–445（445 aa）
Chain BF 1–445（445 aa）
Chain BN 1–445（445 aa）
Chain BP 1–445（445 aa）
Chain BR 1–445（445 aa）
Chain BT 1–445（445 aa）
Chain BV 1–445（445 aa）
Chain BX 1–445（445 aa）
Chain BZ 1–445（445 aa）
Chain Bb 1–445（445 aa）
Chain Bd 1–445（445 aa）
Chain Bf 1–445（445 aa）
Chain Bh 1–445（445 aa）
Chain Bj 1–445（445 aa）
Chain Bl 1–445（445 aa）
Chain Bn 1–445（445 aa）
Chain Bq 1–445（445 aa）
Chain Bs 1–445（445 aa）
Chain Bu 1–445（445 aa）
Chain Bw 1–445（445 aa）
Chain By 1–445（445 aa）
Chain C2 1–445（445 aa）
Chain C4 1–445（445 aa）
Chain C7 1–445（445 aa）
Chain C9 1–445（445 aa）
Chain CA 1–445（445 aa）
Chain CC 1–445（445 aa）
Chain CE 1–445（445 aa）
Chain CG 1–445（445 aa）
Chain CI 1–445（445 aa）
Chain CM 1–445（445 aa）
Chain CO 1–445（445 aa）
Chain CQ 1–445（445 aa）
Chain CS 1–445（445 aa）
Chain CU 1–445（445 aa）
Chain CW 1–445（445 aa）
Chain CY 1–445（445 aa）
Chain Cb 1–445（445 aa）
Chain Cd 1–445（445 aa）
Chain Cf 1–445（445 aa）
Chain Ch 1–445（445 aa）
Chain Cj 1–445（445 aa）
Chain Cl 1–445（445 aa）
Chain Cn 1–445（445 aa）
Chain Cr 1–445（445 aa）
Chain Ct 1–445（445 aa）
Chain Cv 1–445（445 aa）
Chain Cx 1–445（445 aa）
Chain Cz 1–445（445 aa）
Chain D0 1–445（445 aa）
Chain D1 1–445（445 aa）
Chain D6 1–445（445 aa）
Chain D8 1–445（445 aa）
Chain DA 1–445（445 aa）
Chain DC 1–445（445 aa）
Chain DE 1–445（445 aa）
Chain DG 1–445（445 aa）
Chain DI 1–445（445 aa）
Chain DL 1–445（445 aa）
Chain DN 1–445（445 aa）
Chain DP 1–445（445 aa）
Chain DR 1–445（445 aa）
Chain DT 1–445（445 aa）
Chain DV 1–445（445 aa）
Chain DX 1–445（445 aa）
Chain Da 1–445（445 aa）
Chain Dc 1–445（445 aa）
Chain De 1–445（445 aa）
Chain Dg 1–445（445 aa）
Chain Di 1–445（445 aa）
Chain Dk 1–445（445 aa）
Chain Dm 1–445（445 aa）
Chain Dq 1–445（445 aa）
Chain Ds 1–445（445 aa）
Chain Du 1–445（445 aa）
Chain Dw 1–445（445 aa）
Chain Dy 1–445（445 aa）
Chain E0 1–445（445 aa）
Chain E2 1–445（445 aa）
Chain E4 1–445（445 aa）
Chain E6 1–445（445 aa）
Chain E8 1–445（445 aa）
Chain EB 1–445（445 aa）
Chain ED 1–445（445 aa）
Chain EF 1–445（445 aa）
Chain EK 1–445（445 aa）
Chain EM 1–445（445 aa）
Chain EO 1–445（445 aa）
Chain EQ 1–445（445 aa）
Chain ES 1–445（445 aa）
Chain EU 1–445（445 aa）
Chain EZ 1–445（445 aa）
Chain Eb 1–445（445 aa）
Chain Ed 1–445（445 aa）
Chain Ef 1–445（445 aa）
Chain Eh 1–445（445 aa）
Chain Ej 1–445（445 aa）
Chain En 1–445（445 aa）
Chain Ep 1–445（445 aa）
Chain Er 1–445（445 aa）
Chain Et 1–445（445 aa）
Chain Ev 1–445（445 aa）
Chain Ex 1–445（445 aa）
Chain FB 1–445（445 aa）
Chain FD 1–445（445 aa）
Chain FF 1–445（445 aa）
Chain FH 1–445（445 aa）
Chain FJ 1–445（445 aa）
Chain FL 1–445（445 aa）
Chain FN 1–445（445 aa）
Chain FP 1–445（445 aa）
Chain FR 1–445（445 aa）
Chain FT 1–445（445 aa）
Chain FV 1–445（445 aa）
Chain FX 1–445（445 aa）
Chain FZ 1–445（445 aa）
Chain Fb 1–445（445 aa）
Chain Fd 1–445（445 aa）
Chain Ff 1–445（445 aa）
Chain O 1–445（445 aa）
Chain Q 1–445（445 aa）
Chain S 1–445（445 aa）
Chain U 1–445（445 aa）
Chain W 1–445（445 aa）
Chain Y 1–445（445 aa）
Chain o 1–445（445 aa）
Chain q 1–445（445 aa）
Chain s 1–445（445 aa）
Chain u 1–445（445 aa）
Chain w 1–445（445 aa）
Chain y 1–445（445 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 7.70 Å
9IJJ In situ structure of the central apparatus in mouse sperm axoneme. Deposited 2024-06-23 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 464 PDB declaration: 464-meric
Chain Ab 1–445（445 aa）
Chain Ad 1–445（445 aa）
Chain Af 1–445（445 aa）
Chain Ah 1–445（445 aa）
Chain Aj 1–445（445 aa）
Chain An 1–445（445 aa）
Chain Ap 1–445（445 aa）
Chain Ar 1–445（445 aa）
Chain At 1–445（445 aa）
Chain Av 1–445（445 aa）
Chain Bb 1–445（445 aa）
Chain Bd 1–445（445 aa）
Chain Bf 1–445（445 aa）
Chain Bh 1–445（445 aa）
Chain Bj 1–445（445 aa）
Chain Bn 1–445（445 aa）
Chain Bp 1–445（445 aa）
Chain Br 1–445（445 aa）
Chain Bt 1–445（445 aa）
Chain Bv 1–445（445 aa）
Chain Cb 1–445（445 aa）
Chain Cd 1–445（445 aa）
Chain Cf 1–445（445 aa）
Chain Ch 1–445（445 aa）
Chain Cj 1–445（445 aa）
Chain Cn 1–445（445 aa）
Chain Cp 1–445（445 aa）
Chain Cr 1–445（445 aa）
Chain Ct 1–445（445 aa）
Chain Cv 1–445（445 aa）
Chain Db 1–445（445 aa）
Chain Dd 1–445（445 aa）
Chain Df 1–445（445 aa）
Chain Dh 1–445（445 aa）
Chain Dj 1–445（445 aa）
Chain Dn 1–445（445 aa）
Chain Dp 1–445（445 aa）
Chain Dr 1–445（445 aa）
Chain Dt 1–445（445 aa）
Chain Dv 1–445（445 aa）
Chain Eb 1–445（445 aa）
Chain Ed 1–445（445 aa）
Chain Ef 1–445（445 aa）
Chain Eh 1–445（445 aa）
Chain Ej 1–445（445 aa）
Chain En 1–445（445 aa）
Chain Ep 1–445（445 aa）
Chain Er 1–445（445 aa）
Chain Et 1–445（445 aa）
Chain Ev 1–445（445 aa）
Chain Fb 1–445（445 aa）
Chain Fd 1–445（445 aa）
Chain Ff 1–445（445 aa）
Chain Fh 1–445（445 aa）
Chain Fj 1–445（445 aa）
Chain Fn 1–445（445 aa）
Chain Fp 1–445（445 aa）
Chain Fr 1–445（445 aa）
Chain Ft 1–445（445 aa）
Chain Fv 1–445（445 aa）
Chain Gb 1–445（445 aa）
Chain Gd 1–445（445 aa）
Chain Gf 1–445（445 aa）
Chain Gh 1–445（445 aa）
Chain Gj 1–445（445 aa）
Chain Gn 1–445（445 aa）
Chain Gp 1–445（445 aa）
Chain Gr 1–445（445 aa）
Chain Gt 1–445（445 aa）
Chain Gv 1–445（445 aa）
Chain Hb 1–445（445 aa）
Chain Hd 1–445（445 aa）
Chain Hf 1–445（445 aa）
Chain Hh 1–445（445 aa）
Chain Hj 1–445（445 aa）
Chain Hn 1–445（445 aa）
Chain Hp 1–445（445 aa）
Chain Hr 1–445（445 aa）
Chain Ht 1–445（445 aa）
Chain Hv 1–445（445 aa）
Chain Ib 1–445（445 aa）
Chain Id 1–445（445 aa）
Chain If 1–445（445 aa）
Chain Ih 1–445（445 aa）
Chain Ij 1–445（445 aa）
Chain In 1–445（445 aa）
Chain Ip 1–445（445 aa）
Chain Ir 1–445（445 aa）
Chain It 1–445（445 aa）
Chain Iv 1–445（445 aa）
Chain Jb 1–445（445 aa）
Chain Jd 1–445（445 aa）
Chain Jf 1–445（445 aa）
Chain Jh 1–445（445 aa）
Chain Jj 1–445（445 aa）
Chain Jn 1–445（445 aa）
Chain Jp 1–445（445 aa）
Chain Jr 1–445（445 aa）
Chain Jt 1–445（445 aa）
Chain Jv 1–445（445 aa）
Chain Kb 1–445（445 aa）
Chain Kd 1–445（445 aa）
Chain Kf 1–445（445 aa）
Chain Kh 1–445（445 aa）
Chain Kj 1–445（445 aa）
Chain Kn 1–445（445 aa）
Chain Kp 1–445（445 aa）
Chain Kr 1–445（445 aa）
Chain Kt 1–445（445 aa）
Chain Kv 1–445（445 aa）
Chain Lb 1–445（445 aa）
Chain Ld 1–445（445 aa）
Chain Lf 1–445（445 aa）
Chain Lh 1–445（445 aa）
Chain Lj 1–445（445 aa）
Chain Ln 1–445（445 aa）
Chain Lp 1–445（445 aa）
Chain Lr 1–445（445 aa）
Chain Lt 1–445（445 aa）
Chain Lv 1–445（445 aa）
Chain Mb 1–445（445 aa）
Chain Md 1–445（445 aa）
Chain Mf 1–445（445 aa）
Chain Mh 1–445（445 aa）
Chain Mj 1–445（445 aa）
Chain Mn 1–445（445 aa）
Chain Mp 1–445（445 aa）
Chain Mr 1–445（445 aa）
Chain Mt 1–445（445 aa）
Chain Mv 1–445（445 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 7.70 Å
9V10 Cryo-EM structure of the 48-nm repeat doublet microtubule from mouse sperm Deposited 2025-05-19 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 589 PDB declaration: 589-meric
Chain AB 1–445（445 aa）
Chain AD 1–445（445 aa）
Chain AF 1–445（445 aa）
Chain AH 1–445（445 aa）
Chain AJ 1–445（445 aa）
Chain AL 1–445（445 aa）
Chain AN 1–445（445 aa）
Chain AP 1–445（445 aa）
Chain BB 1–445（445 aa）
Chain BD 1–445（445 aa）
Chain BF 1–445（445 aa）
Chain BH 1–445（445 aa）
Chain BJ 1–445（445 aa）
Chain BL 1–445（445 aa）
Chain BN 1–445（445 aa）
Chain BP 1–445（445 aa）
Chain CD 1–445（445 aa）
Chain CF 1–445（445 aa）
Chain CH 1–445（445 aa）
Chain CJ 1–445（445 aa）
Chain CL 1–445（445 aa）
Chain CN 1–445（445 aa）
Chain CP 1–445（445 aa）
Chain DD 1–445（445 aa）
Chain DF 1–445（445 aa）
Chain DH 1–445（445 aa）
Chain DJ 1–445（445 aa）
Chain DL 1–445（445 aa）
Chain DN 1–445（445 aa）
Chain DP 1–445（445 aa）
Chain EB 1–445（445 aa）
Chain ED 1–445（445 aa）
Chain EF 1–445（445 aa）
Chain EH 1–445（445 aa）
Chain EJ 1–445（445 aa）
Chain EL 1–445（445 aa）
Chain EN 1–445（445 aa）
Chain FB 1–445（445 aa）
Chain FD 1–445（445 aa）
Chain FF 1–445（445 aa）
Chain FH 1–445（445 aa）
Chain FJ 1–445（445 aa）
Chain FL 1–445（445 aa）
Chain FN 1–445（445 aa）
Chain GB 1–445（445 aa）
Chain GD 1–445（445 aa）
Chain GF 1–445（445 aa）
Chain GH 1–445（445 aa）
Chain GJ 1–445（445 aa）
Chain GL 1–445（445 aa）
Chain GN 1–445（445 aa）
Chain HB 1–445（445 aa）
Chain HD 1–445（445 aa）
Chain HF 1–445（445 aa）
Chain HH 1–445（445 aa）
Chain HJ 1–445（445 aa）
Chain HL 1–445（445 aa）
Chain HN 1–445（445 aa）
Chain IB 1–445（445 aa）
Chain ID 1–445（445 aa）
Chain IF 1–445（445 aa）
Chain IH 1–445（445 aa）
Chain IJ 1–445（445 aa）
Chain IL 1–445（445 aa）
Chain IN 1–445（445 aa）
Chain IP 1–445（445 aa）
Chain JD 1–445（445 aa）
Chain JF 1–445（445 aa）
Chain JH 1–445（445 aa）
Chain JJ 1–445（445 aa）
Chain JL 1–445（445 aa）
Chain JN 1–445（445 aa）
Chain JP 1–445（445 aa）
Chain KB 1–445（445 aa）
Chain KD 1–445（445 aa）
Chain KF 1–445（445 aa）
Chain KH 1–445（445 aa）
Chain KJ 1–445（445 aa）
Chain KL 1–445（445 aa）
Chain KN 1–445（445 aa）
Chain KP 1–445（445 aa）
Chain LB 1–445（445 aa）
Chain LD 1–445（445 aa）
Chain LF 1–445（445 aa）
Chain LH 1–445（445 aa）
Chain LJ 1–445（445 aa）
Chain LL 1–445（445 aa）
Chain LN 1–445（445 aa）
Chain LP 1–445（445 aa）
Chain MB 1–445（445 aa）
Chain MD 1–445（445 aa）
Chain MF 1–445（445 aa）
Chain MH 1–445（445 aa）
Chain MJ 1–445（445 aa）
Chain ML 1–445（445 aa）
Chain MN 1–445（445 aa）
Chain MP 1–445（445 aa）
Chain NB 1–445（445 aa）
Chain ND 1–445（445 aa）
Chain NF 1–445（445 aa）
Chain NH 1–445（445 aa）
Chain NJ 1–445（445 aa）
Chain NL 1–445（445 aa）
Chain NN 1–445（445 aa）
Chain NP 1–445（445 aa）
Chain OB 1–445（445 aa）
Chain OD 1–445（445 aa）
Chain OF 1–445（445 aa）
Chain OH 1–445（445 aa）
Chain OJ 1–445（445 aa）
Chain OL 1–445（445 aa）
Chain ON 1–445（445 aa）
Chain OP 1–445（445 aa）
Chain PB 1–445（445 aa）
Chain PD 1–445（445 aa）
Chain PF 1–445（445 aa）
Chain PH 1–445（445 aa）
Chain PJ 1–445（445 aa）
Chain PL 1–445（445 aa）
Chain PN 1–445（445 aa）
Chain PP 1–445（445 aa）
Chain QD 1–445（445 aa）
Chain QF 1–445（445 aa）
Chain QH 1–445（445 aa）
Chain QJ 1–445（445 aa）
Chain QL 1–445（445 aa）
Chain QN 1–445（445 aa）
Chain QP 1–445（445 aa）
Chain RD 1–445（445 aa）
Chain RF 1–445（445 aa）
Chain RH 1–445（445 aa）
Chain RJ 1–445（445 aa）
Chain RL 1–445（445 aa）
Chain RN 1–445（445 aa）
Chain RP 1–445（445 aa）
Chain SB 1–445（445 aa）
Chain SD 1–445（445 aa）
Chain SF 1–445（445 aa）
Chain SH 1–445（445 aa）
Chain SJ 1–445（445 aa）
Chain SL 1–445（445 aa）
Chain SN 1–445（445 aa）
Chain TB 1–445（445 aa）
Chain TD 1–445（445 aa）
Chain TF 1–445（445 aa）
Chain TH 1–445（445 aa）
Chain TJ 1–445（445 aa）
Chain TL 1–445（445 aa）
Chain TN 1–445（445 aa）
Chain UB 1–445（445 aa）
Chain UD 1–445（445 aa）
Chain UF 1–445（445 aa）
Chain UH 1–445（445 aa）
Chain UJ 1–445（445 aa）
Chain UL 1–445（445 aa）
Chain UN 1–445（445 aa）
Chain VB 1–445（445 aa）
Chain VD 1–445（445 aa）
Chain VF 1–445（445 aa）
Chain VH 1–445（445 aa）
Chain VJ 1–445（445 aa）
Chain VL 1–445（445 aa）
Chain VN 1–445（445 aa）
Chain WB 1–445（445 aa）
Chain WD 1–445（445 aa）
Chain WF 1–445（445 aa）
Chain WH 1–445（445 aa）
Chain WJ 1–445（445 aa）
Chain WL 1–445（445 aa）
Chain WN 1–445（445 aa）
Not recorded GTP GUANOSINE-5'-TRIPHOSPHATE × 167 MG MAGNESIUM ION × 170 GDP GUANOSINE-5'-DIPHOSPHATE × 170 ATP ADENOSINE-5'-TRIPHOSPHATE × 3 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.2
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.70 Å
9XRL Structure of mouse cytoplasmic lattice (CPL) repeating unit Deposited 2025-11-19 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 73 PDB declaration: 73-meric
Chain AE 1–445（445 aa）
Chain AN 1–445（445 aa）
Chain t 1–445（445 aa）
Not recorded ZN ZINC ION × 13 GTP GUANOSINE-5'-TRIPHOSPHATE × 5 MG MAGNESIUM ION × 4 ADP ADENOSINE-5'-DIPHOSPHATE × 3 ELECTRON MICROSCOPY
cryo-EM buffer pH 6.7
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.74 Å

8 other PDB entries and 8 assemblies. Open the comparison page and filter oligomeric states

View Construct and Data Evidence
UniProt name TBB4B_MOUSE
Isoform —
PDB entities 10
Chains and sequence ranges Author chain b； PDBConstruct 1–445； UniProt 1–445

Ubiquitin-conjugating enzyme E2 D3

OrganismNot specified

UniProt P61079

State in the Current Structure

Assembly Oligomeric State Construct Mutations and Modifications Ligands, Ions and Associated Components Method and Experimental Conditions Structure Quality
1 Protein heterocomplex Heteromer Protein × 54 PDB declaration: 54-meric（54） Consistent with protein copy count Chain c； UniProt 1–147 Not recorded F-box and WD-40 domain protein 12 × 4 （Q5U467） KH domain-containing protein 3 × 2 （Q9CWU5） NLR family, pyrin domain containing 4F × 4 （L7N1W9） NACHT, LRR and PYD domains-containing protein 5 × 4 （Q9R1M5） NACHT, LRR and PYD domains-containing protein 14 × 2 （Q6B966） Oocyte-expressed protein homolog × 4 （Q9CWE6） Inactive protein-arginine deiminase type-6 × 20 （Q8K3V4） Transducin-like enhancer protein 6 × 4 （Q9WVB3） Tubulin alpha-1A chain × 2 （P68369） Tubulin beta-4B chain × 2 （P68372） E3 ubiquitin-protein ligase UHRF1 × 2 （Q8VDF2） Zinc finger BED domain-containing protein 3 × 2 （Q9D0L1） ELECTRON MICROSCOPY cryo-EM buffer：pH 7.2 cryo-EM vitrification conditions：Cryogen ETHANE-PROPANE Resolution 4.20 Å

Other States of the Same Protein in the Database

Each row is a biological assembly of the same UniProt protein in another PDB entry. The “Difference from current entry” column identifies evidence-level differences; no tag means the currently parsed fields agree.

Other PDB Difference from Current Entry 9SFP Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Method and Experimental Conditions Structure Quality
12DL Native structure of the cytoplasmic lattice (CPL) asymmetric unit from mouse MII eggs Deposited 2026-03-29 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 33 PDB declaration: 33-meric
Chain CA 1–147（147 aa）
Chain CB 1–147（147 aa）
Not recorded GTP GUANOSINE-5'-TRIPHOSPHATE × 2 MG MAGNESIUM ION × 2 ZN ZINC ION × 11 CA CALCIUM ION × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.50 Å
24MC Structure of oocyte cytoplasmic lattices Deposited 2026-03-10 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 36 PDB declaration: 36-meric
Chain a 1–147（147 aa）
Chain c 1–147（147 aa）
Not recorded ATP ADENOSINE-5'-TRIPHOSPHATE × 5 GTP GUANOSINE-5'-TRIPHOSPHATE × 4 MG MAGNESIUM ION × 4 ZN ZINC ION × 6 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.40 Å
9W2M Cryo-EM structure of the Cytoplasmic lattice(CPL) from mouse oocyte Deposited 2025-07-28 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Assembly 1 Protein heterocomplex Heteromer；Protein × 56 PDB declaration: 56-meric
Chain O 1–147（147 aa）
Chain o 1–147（147 aa）
Not recorded GDP GUANOSINE-5'-DIPHOSPHATE × 4 ADP ADENOSINE-5'-DIPHOSPHATE × 4 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.20 Å
9XRL Structure of mouse cytoplasmic lattice (CPL) repeating unit Deposited 2025-11-19 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 73 PDB declaration: 73-meric
Chain AD 1–147（147 aa）
Chain AM 1–147（147 aa）
Chain AS 1–147（147 aa）
Not recorded ZN ZINC ION × 13 GTP GUANOSINE-5'-TRIPHOSPHATE × 5 MG MAGNESIUM ION × 4 ADP ADENOSINE-5'-DIPHOSPHATE × 3 ELECTRON MICROSCOPY
cryo-EM buffer pH 6.7
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.74 Å

4 other PDB entries and 4 assemblies. Open the comparison page and filter oligomeric states

View Construct and Data Evidence
UniProt name UB2D3_MOUSE
Isoform —
PDB entities 11
Chains and sequence ranges Author chain c； PDBConstruct 1–147； UniProt 1–147

E3 ubiquitin-protein ligase UHRF1

OrganismNot specified

UniProt Q8VDF2

State in the Current Structure

Assembly Oligomeric State Construct Mutations and Modifications Ligands, Ions and Associated Components Method and Experimental Conditions Structure Quality
1 Protein heterocomplex Heteromer Protein × 54 PDB declaration: 54-meric（54） Consistent with protein copy count Chain d； UniProt 1–782 Not recorded F-box and WD-40 domain protein 12 × 4 （Q5U467） KH domain-containing protein 3 × 2 （Q9CWU5） NLR family, pyrin domain containing 4F × 4 （L7N1W9） NACHT, LRR and PYD domains-containing protein 5 × 4 （Q9R1M5） NACHT, LRR and PYD domains-containing protein 14 × 2 （Q6B966） Oocyte-expressed protein homolog × 4 （Q9CWE6） Inactive protein-arginine deiminase type-6 × 20 （Q8K3V4） Transducin-like enhancer protein 6 × 4 （Q9WVB3） Tubulin alpha-1A chain × 2 （P68369） Tubulin beta-4B chain × 2 （P68372） Ubiquitin-conjugating enzyme E2 D3 × 2 （P61079） Zinc finger BED domain-containing protein 3 × 2 （Q9D0L1） ELECTRON MICROSCOPY cryo-EM buffer：pH 7.2 cryo-EM vitrification conditions：Cryogen ETHANE-PROPANE Resolution 4.20 Å

Other States of the Same Protein in the Database

Each row is a biological assembly of the same UniProt protein in another PDB entry. The “Difference from current entry” column identifies evidence-level differences; no tag means the currently parsed fields agree.

Other PDB Difference from Current Entry 9SFP Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Method and Experimental Conditions Structure Quality
12DL Native structure of the cytoplasmic lattice (CPL) asymmetric unit from mouse MII eggs Deposited 2026-03-29 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 33 PDB declaration: 33-meric
Chain BA 1–782（782 aa）
Chain BB 1–782（782 aa）
Not recorded GTP GUANOSINE-5'-TRIPHOSPHATE × 2 MG MAGNESIUM ION × 2 ZN ZINC ION × 11 CA CALCIUM ION × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.50 Å
24MC Structure of oocyte cytoplasmic lattices Deposited 2026-03-10 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 36 PDB declaration: 36-meric
Chain b 1–782（782 aa）
Chain d 1–782（782 aa）
Not recorded ATP ADENOSINE-5'-TRIPHOSPHATE × 5 GTP GUANOSINE-5'-TRIPHOSPHATE × 4 MG MAGNESIUM ION × 4 ZN ZINC ION × 6 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.40 Å
2ZKD Crystal structure of the SRA domain of mouse Np95 in complex with hemi-methylated CpG DNA Deposited 2008-03-19 Different construct Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein–DNA Monomer；Protein × 1 PDB declaration: trimeric
Chain A 404–613（210 aa） Fragment：UNP residues 404-613
Not recorded ACT ACETATE ION × 1 EDO 1,2-ETHANEDIOL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.6；293 K；0.1M sodium citrate (pH5.6), 0.2M sodium acetate, 30% PEG4000, VAPOR DIFFUSION, HANGING DROP, temperature 293K
Resolution 1.60 Å R-free 0.185
2ZKD Crystal structure of the SRA domain of mouse Np95 in complex with hemi-methylated CpG DNA Deposited 2008-03-19 Different construct Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 2 Protein–DNA Monomer；Protein × 1 PDB declaration: trimeric
Chain B 404–613（210 aa） Fragment：UNP residues 404-613
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.6；293 K；0.1M sodium citrate (pH5.6), 0.2M sodium acetate, 30% PEG4000, VAPOR DIFFUSION, HANGING DROP, temperature 293K
Resolution 1.60 Å R-free 0.185
2ZKE Crystal structure of the SRA domain of mouse Np95 in complex with hemi-methylated CpG DNA Deposited 2008-03-19 Different construct Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein–DNA Monomer；Protein × 1 PDB declaration: trimeric
Chain A 404–613（210 aa） Fragment：UNP residues 404-613
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.5；293 K；0.1M Bis-Tris-propane (pH7.5), 0.2M sodium fluoride, 20% PEG3350, VAPOR DIFFUSION, HANGING DROP, temperature 293K
Resolution 2.60 Å R-free 0.275
2ZKF Crystal structure of the SRA domain of mouse Np95 in complex with hemi-methylated CpG DNA Deposited 2008-03-19 Different construct Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein–DNA Monomer；Protein × 1 PDB declaration: trimeric
Chain A 404–613（210 aa） Fragment：UNP residues 404-613
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.5；293 K；0.1M Bis-Tris-propane (pH7.5), 0.2M sodium fluoride, 20% PEG3350, VAPOR DIFFUSION, HANGING DROP, temperature 293K
Resolution 2.55 Å R-free 0.275
2ZKG Crystal structure of unliganded SRA domain of mouse Np95 Deposited 2008-03-19 Different construct Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 404–613（210 aa） Fragment：UNP residues 404-613
Not recorded EDO 1,2-ETHANEDIOL × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8；277 K；0.1M Tris-HCl (pH8.0), 0.1M Sodium acetate, 12% PEG3350, VAPOR DIFFUSION, HANGING DROP, temperature 277K
Resolution 1.77 Å R-free 0.217
2ZKG Crystal structure of unliganded SRA domain of mouse Np95 Deposited 2008-03-19 Different construct Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain B 404–613（210 aa） Fragment：UNP residues 404-613
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8；277 K；0.1M Tris-HCl (pH8.0), 0.1M Sodium acetate, 12% PEG3350, VAPOR DIFFUSION, HANGING DROP, temperature 277K
Resolution 1.77 Å R-free 0.217
2ZKG Crystal structure of unliganded SRA domain of mouse Np95 Deposited 2008-03-19 Different construct Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain C 404–613（210 aa） Fragment：UNP residues 404-613
Not recorded EDO 1,2-ETHANEDIOL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8；277 K；0.1M Tris-HCl (pH8.0), 0.1M Sodium acetate, 12% PEG3350, VAPOR DIFFUSION, HANGING DROP, temperature 277K
Resolution 1.77 Å R-free 0.217
2ZKG Crystal structure of unliganded SRA domain of mouse Np95 Deposited 2008-03-19 Different construct Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain D 404–613（210 aa） Fragment：UNP residues 404-613
Not recorded EDO 1,2-ETHANEDIOL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8；277 K；0.1M Tris-HCl (pH8.0), 0.1M Sodium acetate, 12% PEG3350, VAPOR DIFFUSION, HANGING DROP, temperature 277K
Resolution 1.77 Å R-free 0.217
2ZO0 mouse NP95 SRA domain DNA specific complex 1 Deposited 2008-05-05 Different construct Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein–DNA Monomer；Protein × 1 PDB declaration: trimeric
Chain B 419–628（210 aa） Fragment：SRA domain, residues 419-628
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7；289 K；20% (v/v) polyethylene glycol 3350, 0.4M NaCl, pH 7.0, VAPOR DIFFUSION, HANGING DROP, temperature 289K
Resolution 2.19 Å R-free 0.253
2ZO0 mouse NP95 SRA domain DNA specific complex 1 Deposited 2008-05-05 Different construct Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain B 419–628（210 aa） Fragment：SRA domain, residues 419-628
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7；289 K；20% (v/v) polyethylene glycol 3350, 0.4M NaCl, pH 7.0, VAPOR DIFFUSION, HANGING DROP, temperature 289K
Resolution 2.19 Å R-free 0.253
2ZO1 Mouse NP95 SRA domain DNA specific complex 2 Deposited 2008-05-05 Different construct Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein–DNA Monomer；Protein × 1 PDB declaration: trimeric
Chain B 419–628（210 aa） Fragment：SRA domain, residues 419-628
Not recorded EDO 1,2-ETHANEDIOL × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7；289 K；20% (v/v) polyethylene glycol 3350, 0.4M NaCl, pH 7.0, VAPOR DIFFUSION, HANGING DROP, temperature 289K
Resolution 1.96 Å R-free 0.246
2ZO1 Mouse NP95 SRA domain DNA specific complex 2 Deposited 2008-05-05 Different construct Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain B 419–628（210 aa） Fragment：SRA domain, residues 419-628
Not recorded EDO 1,2-ETHANEDIOL × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7；289 K；20% (v/v) polyethylene glycol 3350, 0.4M NaCl, pH 7.0, VAPOR DIFFUSION, HANGING DROP, temperature 289K
Resolution 1.96 Å R-free 0.246
2ZO2 Mouse NP95 SRA domain non-specific DNA complex Deposited 2008-05-05 Different construct Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein–DNA Monomer；Protein × 1 PDB declaration: trimeric
Chain B 419–628（210 aa） Fragment：SRA domain, residues 419-628
Not recorded PO4 PHOSPHATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；289 K；20% (v/v) polyethylene glycol 3350 or 10000, 0.2-0.4M NaCl, 0.1M MES(pH 5.8-6.2), VAPOR DIFFUSION, HANGING DROP, temperature 289K
Resolution 3.09 Å R-free 0.291
2ZO2 Mouse NP95 SRA domain non-specific DNA complex Deposited 2008-05-05 Different construct Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain B 419–628（210 aa） Fragment：SRA domain, residues 419-628
Not recorded PO4 PHOSPHATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；289 K；20% (v/v) polyethylene glycol 3350 or 10000, 0.2-0.4M NaCl, 0.1M MES(pH 5.8-6.2), VAPOR DIFFUSION, HANGING DROP, temperature 289K
Resolution 3.09 Å R-free 0.291
2ZO2 Mouse NP95 SRA domain non-specific DNA complex Deposited 2008-05-05 Different construct Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 4 Protein–DNA Homooligomer；Protein × 2 PDB declaration: hexameric
Chain B 419–628（210 aa） Fragment：SRA domain, residues 419-628
Not recorded PO4 PHOSPHATE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；289 K；20% (v/v) polyethylene glycol 3350 or 10000, 0.2-0.4M NaCl, 0.1M MES(pH 5.8-6.2), VAPOR DIFFUSION, HANGING DROP, temperature 289K
Resolution 3.09 Å R-free 0.291
3F8I Mouse UHRF1 SRA domain bound with hemi-methylated CpG, crystal structure in space group P21 Deposited 2008-11-12 Different construct Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein–DNA Monomer；Protein × 1 PDB declaration: trimeric
Chain A 418–628（211 aa） Fragment：YDG domain: UNP residues 419-628
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions pH 7；277 K；20% PEG 3350, 0.4M NaCl, pH 7.0, VAPOR DIFFUSION, temperature 277K
Resolution 2.29 Å R-free 0.268
3F8I Mouse UHRF1 SRA domain bound with hemi-methylated CpG, crystal structure in space group P21 Deposited 2008-11-12 Different construct Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 2 Protein–DNA Monomer；Protein × 1 PDB declaration: trimeric
Chain B 418–628（211 aa） Fragment：YDG domain: UNP residues 419-628
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions pH 7；277 K；20% PEG 3350, 0.4M NaCl, pH 7.0, VAPOR DIFFUSION, temperature 277K
Resolution 2.29 Å R-free 0.268
3F8J Mouse UHRF1 SRA domain bound with hemi-methylated CpG, crystal structure in space group C222(1) Deposited 2008-11-12 Different construct Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein–DNA Monomer；Protein × 1 PDB declaration: trimeric
Chain B 417–628（212 aa） Fragment：YDG domain: UNP residues 417-628
Not recorded GOL GLYCEROL × 9 X-RAY DIFFRACTION
X-ray crystallization conditions pH 7；277 K；20% PEG 3350, 0.4 M NaCl, pH 7.0, VAPOR DIFFUSION, temperature 277K
Resolution 1.99 Å R-free 0.232
3FDE Mouse UHRF1 SRA domain bound with hemi-methylated CpG DNA, crystal structure in space group C222(1) at 1.4 A resolution Deposited 2008-11-25 Different construct Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein–DNA Monomer；Protein × 1 PDB declaration: trimeric
Chain A 419–628（210 aa） Fragment：YDG domain: UNP residues 419-628
Not recorded EDO 1,2-ETHANEDIOL × 11 NA SODIUM ION × 2 UNL UNKNOWN LIGAND × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 7；277 K；20% PEG 3350, 0.4M NaCl, pH 7.0, VAPOR DIFFUSION, temperature 277K
Resolution 1.41 Å R-free 0.186
3FDE Mouse UHRF1 SRA domain bound with hemi-methylated CpG DNA, crystal structure in space group C222(1) at 1.4 A resolution Deposited 2008-11-25 Different construct Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 2 Protein–DNA Monomer；Protein × 1 PDB declaration: trimeric
Chain B 419–628（210 aa） Fragment：YDG domain: UNP residues 419-628
Not recorded EDO 1,2-ETHANEDIOL × 11 NA SODIUM ION × 2 UNL UNKNOWN LIGAND × 7 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 7；277 K；20% PEG 3350, 0.4M NaCl, pH 7.0, VAPOR DIFFUSION, temperature 277K
Resolution 1.41 Å R-free 0.186
6M2V Crystal structure of UHRF1 SRA complexed with fully-mCHG DNA. Deposited 2020-03-01 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein–DNA Homooligomer；Protein × 2 PDB declaration: tetrameric
Chain A 417–628（212 aa）
Chain B 417–628（212 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8；291 K；0.1M Bis-Tris, pH 8.0, 0.2M NaCl, 12% PEG 3,350
Resolution 3.00 Å R-free 0.276
6VEE Solution structure of the TTD and linker region of mouse UHRF1 (NP95) Deposited 2019-12-31 Different construct Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 122–305（184 aa）
Not recorded No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 7.5；303 K；Ionic strength (raw mmCIF value) 150；Pressure 1
NMR sample composition 250 uM [U-99% 13C; U-99% 15N] TTD-linker, 50 mM sodium phosphate, 5 mM DTT, 5 mM TCEP, 2 mM beta-mercaptoethanol, 150 mM sodium chloride, 95% H2O/5% D2O | 95% H2O/5% D2O
Resolution not provided
6VFO Solution structure of the PHD of mouse UHRF1 (NP95) Deposited 2020-01-06 Different construct Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 303–380（78 aa）
Not recorded ZN ZINC ION × 3 SOLUTION NMR
NMR measurement conditions pH 7.5；290 K；Ionic strength (raw mmCIF value) 150；Pressure 1
NMR sample composition 200 uM [U-99% 13C; U-99% 15N] PHD, 5 mM DTT, 2 mM beta-mercaptoethanol, 5 mM TCEP, 150 mM sodium chloride, 50 mM sodium phosphate, 95% H2O/5% D2O | 95% H2O/5% D2O
Resolution not provided
7XGA NMR strucutre of chimeric protein for model of PHD-Stella complex Deposited 2022-04-04 Different construct Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Monomer；Protein × 1 PDB declaration: monomeric
Chain A 304–372（69 aa）
Not recorded ZN ZINC ION × 3 SOLUTION NMR
NMR measurement conditions pH 7；293 K；Ionic strength (raw mmCIF value) 50；Pressure 1
NMR measurement conditions pH 7；293 K；Ionic strength (raw mmCIF value) 50；Pressure 1
NMR sample composition 0.66 mM [U-100% 13C; U-100% 15N] PHD_Stella, 10 mM sodium phosphate, 50 mM sodium chloride, 90% H2O/10% D2O | 90% H2O/10% D2O
NMR sample composition 0.66 mM [U-100% 13C; U-100% 15N] PHD_Stella, 10 mM sodium phosphate, 50 mM sodium chloride, 100% D2O | 100% D2O
Resolution not provided
9W2M Cryo-EM structure of the Cytoplasmic lattice(CPL) from mouse oocyte Deposited 2025-07-28 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Assembly 1 Protein heterocomplex Heteromer；Protein × 56 PDB declaration: 56-meric
Chain P 1–782（782 aa）
Chain Q 1–782（782 aa）
Chain p 1–782（782 aa）
Chain q 1–782（782 aa）
Not recorded GDP GUANOSINE-5'-DIPHOSPHATE × 4 ADP ADENOSINE-5'-DIPHOSPHATE × 4 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.20 Å
9XRL Structure of mouse cytoplasmic lattice (CPL) repeating unit Deposited 2025-11-19 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 73 PDB declaration: 73-meric
Chain AL 1–782（782 aa）
Chain AR 1–782（782 aa）
Chain x 1–782（782 aa）
Not recorded ZN ZINC ION × 13 GTP GUANOSINE-5'-TRIPHOSPHATE × 5 MG MAGNESIUM ION × 4 ADP ADENOSINE-5'-DIPHOSPHATE × 3 ELECTRON MICROSCOPY
cryo-EM buffer pH 6.7
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.74 Å

18 other PDB entries and 28 assemblies. Open the comparison page and filter oligomeric states

View Construct and Data Evidence
UniProt name UHRF1_MOUSE
Isoform —
PDB entities 12
Chains and sequence ranges Author chain d； PDBConstruct 1–782； UniProt 1–782

Zinc finger BED domain-containing protein 3

OrganismNot specified

UniProt Q9D0L1

State in the Current Structure

Assembly Oligomeric State Construct Mutations and Modifications Ligands, Ions and Associated Components Method and Experimental Conditions Structure Quality
1 Protein heterocomplex Heteromer Protein × 54 PDB declaration: 54-meric（54） Consistent with protein copy count Chain e； UniProt 1–228 Not recorded F-box and WD-40 domain protein 12 × 4 （Q5U467） KH domain-containing protein 3 × 2 （Q9CWU5） NLR family, pyrin domain containing 4F × 4 （L7N1W9） NACHT, LRR and PYD domains-containing protein 5 × 4 （Q9R1M5） NACHT, LRR and PYD domains-containing protein 14 × 2 （Q6B966） Oocyte-expressed protein homolog × 4 （Q9CWE6） Inactive protein-arginine deiminase type-6 × 20 （Q8K3V4） Transducin-like enhancer protein 6 × 4 （Q9WVB3） Tubulin alpha-1A chain × 2 （P68369） Tubulin beta-4B chain × 2 （P68372） Ubiquitin-conjugating enzyme E2 D3 × 2 （P61079） E3 ubiquitin-protein ligase UHRF1 × 2 （Q8VDF2） ELECTRON MICROSCOPY cryo-EM buffer：pH 7.2 cryo-EM vitrification conditions：Cryogen ETHANE-PROPANE Resolution 4.20 Å

Other States of the Same Protein in the Database

Each row is a biological assembly of the same UniProt protein in another PDB entry. The “Difference from current entry” column identifies evidence-level differences; no tag means the currently parsed fields agree.

Other PDB Difference from Current Entry 9SFP Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Method and Experimental Conditions Structure Quality
12DL Native structure of the cytoplasmic lattice (CPL) asymmetric unit from mouse MII eggs Deposited 2026-03-29 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 33 PDB declaration: 33-meric
Chain KA 2–228（227 aa）
Not recorded GTP GUANOSINE-5'-TRIPHOSPHATE × 2 MG MAGNESIUM ION × 2 ZN ZINC ION × 11 CA CALCIUM ION × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.50 Å
24MC Structure of oocyte cytoplasmic lattices Deposited 2026-03-10 Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 36 PDB declaration: 36-meric
Chain V 1–228（228 aa）
Not recorded ATP ADENOSINE-5'-TRIPHOSPHATE × 5 GTP GUANOSINE-5'-TRIPHOSPHATE × 4 MG MAGNESIUM ION × 4 ZN ZINC ION × 6 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.40 Å
9L4J Structure of mouse SCMCcore complex contain ZBED3 Deposited 2024-12-20 Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric
Chain E 34–89（56 aa）
Not recorded ZN ZINC ION × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 8；25mM Tris pH 8.0, 150mM NaCl,5 mM DTT
cryo-EM vitrification conditions Cryogen ETHANE；Vitrification carried out in argon atmosphere
Resolution 3.00 Å
9W2M Cryo-EM structure of the Cytoplasmic lattice(CPL) from mouse oocyte Deposited 2025-07-28 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Assembly 1 Protein heterocomplex Heteromer；Protein × 56 PDB declaration: 56-meric
Chain R 34–88（55 aa）
Chain r 34–88（55 aa）
Not recorded GDP GUANOSINE-5'-DIPHOSPHATE × 4 ADP ADENOSINE-5'-DIPHOSPHATE × 4 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.20 Å
9XRL Structure of mouse cytoplasmic lattice (CPL) repeating unit Deposited 2025-11-19 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 73 PDB declaration: 73-meric
Chain 1 1–228（228 aa）
Chain 3 1–228（228 aa）
Chain 9 1–228（228 aa）
Not recorded ZN ZINC ION × 13 GTP GUANOSINE-5'-TRIPHOSPHATE × 5 MG MAGNESIUM ION × 4 ADP ADENOSINE-5'-DIPHOSPHATE × 3 ELECTRON MICROSCOPY
cryo-EM buffer pH 6.7
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.74 Å

5 other PDB entries and 5 assemblies. Open the comparison page and filter oligomeric states

View Construct and Data Evidence
UniProt name ZBED3_MOUSE
Isoform —
PDB entities 13
Chains and sequence ranges Author chain e； PDBConstruct 1–228； UniProt 1–228

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

SAXS scattering curve SAXS Profile

SAXS profile for 9sfp

P(r) Distance Distribution P(r) Distribution

P(r) distribution for 9sfp
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2. Structure Basics 2. Structure Basics

Entry ID entry_id9sfp
Deposition date deposition_date2025-08-20
Structure title titleNative cytoplasmic lattices from mouse oocytes
Keywords keywordsoocyte, embryo, cytoskeleton, tubulin, ubiquitin, STRUCTURAL PROTEIN; STRUCTURAL PROTEIN
Experimental Method methodELECTRON MICROSCOPY
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3. SAXS Parameters (CRYSOL theoretical calculation) 3. SAXS Parameters (CRYSOL)

Radius of gyration Rg (Guinier) rg_guinier— Å
Radius of gyration Rg (electron density) rg_electron110.20 Å
Forward intensity I(0) i037012500000.00
Molecular weight molecular_weight1673100.0 kDa
Excluded volume excluded_volume2104800 ų
Envelope volume envelope_volume3584800 ų
Hydration-shell volume shell_volume277380 ų
Envelope diameter envelope_diameter406.0 Å
Shell Rg shell_rg97.61 Å
Envelope Rg envelope_rg107.40 Å
Shape Rg shape_rg110.10 Å
Total Rg total_rg110.20 Å
Total atoms total_atoms117354
Residues n_residues14769
Spherical-harmonic order n_harmonics20
q range q_range— – 0.5000 Å−1
Data points n_points101
Shell type shell_typedirectional
Solvent electron density solvent_density0.3340 e/ų
Shell contrast contrast_shell0.0300 e/ų
CRYSOL version crysol_version4.1.3
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4. P(r) Distance Distribution (GNOM inversion) 4. P(r) Analysis (GNOM)

Maximum dimension Dmax dmax297.2 Å
Rg (real space) rg_real104.60 Å
Rg uncertainty (real space) rg_real_error1.07 Å
I(0) (real space) i0_real3.5390e+10
I(0) uncertainty (real space) i0_real_error7.1110e+08
Rg (reciprocal space) rg_reciprocal104.80 Å
I(0) (reciprocal space) i0_reciprocal36410000000.0000
Solution quality estimate total_estimate0.9132
Solution quality rating solution_quality EXCELLENT a EXCELLENT solution
P(r) peaks n_peaks1
Primary peak position r_peak_primary106.1 Å
Skewness Skewness skewness0.290
Kurtosis Kurtosis kurtosis-0.566
Angular range angular_range— – 0.0700 Å−1
Current regularization parameter α current_alpha0.9832
Highest regularization parameter α highest_alpha1202000000.0000
Real-space data points n_real_points15
GNOM version gnom_version4.1.3
Quality Criteria quality_criteria AN1: 0.003; Oscil: 1.000; Stabil: 0.973; Sysdev: 1.000; Positv: 1.000; Valcen: 0.952; Smooth: 0.000
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5. Crystallography and Experiment 5. Crystallography & Experiment

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6. Entities and Polymers Entities & Polymers (13)

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8. Citations (1)

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9. Files and Curves (10)