当前蛋白身份：P07552
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差异标签只比较当前检索结果；所有PDB和assembly原始记录仍分别保留。
相关结构差异明细
一行代表一个 PDB 条目中的一个 biological assembly；同一蛋白的多个单体会分别列出。
| PDB 条目 | Assembly / 聚集状态 | 构建体 | 突变与修饰 | 配体、离子与非聚合物 | 实验方法 | 实验环境 | 结构质量 |
|---|---|---|---|---|---|---|---|
| 1BE3 CYTOCHROME BC1 COMPLEX FROM BOVINE 提交 1998-05-19 | Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 11 PDB 声明：undecameric（11） 与蛋白数一致 |
链 K
1–56（56 aa）
|
未记录 | HEM PROTOPORPHYRIN IX CONTAINING FE × 2 HEC HEME C × 1 FES FE2/S2 (INORGANIC) CLUSTER × 1 | X-RAY DIFFRACTION |
X-ray结晶条件
pH 6.6；pH 6.6
|
分辨率 3.00 Å R-free 0.320 |
| 1BE3 CYTOCHROME BC1 COMPLEX FROM BOVINE 提交 1998-05-19 | Assembly 2 蛋白异源复合物 异源复合物；蛋白 × 22 PDB 声明：22-meric（22） 与蛋白数一致 |
链 K
1–56（56 aa）
|
未记录 | HEM PROTOPORPHYRIN IX CONTAINING FE × 4 HEC HEME C × 2 FES FE2/S2 (INORGANIC) CLUSTER × 2 | X-RAY DIFFRACTION |
X-ray结晶条件
pH 6.6；pH 6.6
|
分辨率 3.00 Å R-free 0.320 |
| 1BGY CYTOCHROME BC1 COMPLEX FROM BOVINE 提交 1998-06-02 | Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 22 PDB 声明：22-meric（22） 与蛋白数一致 |
链 K
1–56（56 aa）
链 W
1–56（56 aa）
|
未记录 | HEM PROTOPORPHYRIN IX CONTAINING FE × 4 HEC HEME C × 2 FES FE2/S2 (INORGANIC) CLUSTER × 1 | X-RAY DIFFRACTION |
X-ray结晶条件
pH 6.8；pH 6.8
|
分辨率 3.00 Å R-free 0.360 |
| 1L0L structure of bovine mitochondrial cytochrome bc1 complex with a bound fungicide famoxadone 提交 2002-02-11 | Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 11 PDB 声明：undecameric（11） 与蛋白数一致 |
链 K
1–56（56 aa）
|
未记录 | HEM PROTOPORPHYRIN IX CONTAINING FE × 3 FMX FAMOXADONE × 1 FES FE2/S2 (INORGANIC) CLUSTER × 1 | X-RAY DIFFRACTION | mmCIF 未提供已读取条件 | 分辨率 2.35 Å R-free 0.306 |
| 1L0L structure of bovine mitochondrial cytochrome bc1 complex with a bound fungicide famoxadone 提交 2002-02-11 | Assembly 2 蛋白异源复合物 异源复合物；蛋白 × 22 PDB 声明：22-meric（22） 与蛋白数一致 |
链 K
1–56（56 aa）
|
未记录 | HEM PROTOPORPHYRIN IX CONTAINING FE × 6 FMX FAMOXADONE × 2 FES FE2/S2 (INORGANIC) CLUSTER × 2 | X-RAY DIFFRACTION | mmCIF 未提供已读取条件 | 分辨率 2.35 Å R-free 0.306 |
| 1L0N native structure of bovine mitochondrial cytochrome bc1 complex 提交 2002-02-11 | Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 11 PDB 声明：undecameric（11） 与蛋白数一致 |
链 K
1–56（56 aa）
|
未记录 | HEM PROTOPORPHYRIN IX CONTAINING FE × 3 FES FE2/S2 (INORGANIC) CLUSTER × 1 | X-RAY DIFFRACTION | mmCIF 未提供已读取条件 | 分辨率 2.60 Å R-free 0.297 |
| 1L0N native structure of bovine mitochondrial cytochrome bc1 complex 提交 2002-02-11 | Assembly 2 蛋白异源复合物 异源复合物；蛋白 × 22 PDB 声明：22-meric（22） 与蛋白数一致 |
链 K
1–56（56 aa）
|
未记录 | HEM PROTOPORPHYRIN IX CONTAINING FE × 6 FES FE2/S2 (INORGANIC) CLUSTER × 2 | X-RAY DIFFRACTION | mmCIF 未提供已读取条件 | 分辨率 2.60 Å R-free 0.297 |
| 1NTK Crystal Structure of Mitochondrial Cytochrome bc1 in Complex with Antimycin A1 提交 2003-01-30 | Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 22 PDB 声明：22-meric（22） 与蛋白数一致 |
链 K
1–56（56 aa）
|
未记录 | HEM PROTOPORPHYRIN IX CONTAINING FE × 6 AY1 [(2R,3S,6S,7R,8R)-3-[(3-formamido-2-oxidanyl-phenyl)carbonylamino]-8-hexyl-2,6-dimethyl-4,9-bis(oxidanylidene)-1,5-dioxonan-7-yl] 2-methylpropanoate × 2 FES FE2/S2 (INORGANIC) CLUSTER × 2 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION；pH 7.2；277 K；PEG 4000, ammonium acetate, potassium chloride, glycerol, DMG/SPC, MOPS, pH 7.2, VAPOR DIFFUSION, temperature 277K
|
分辨率 2.60 Å R-free 0.270 |
| 1NTM Crystal Structure of Mitochondrial Cytochrome bc1 Complex at 2.4 Angstrom 提交 2003-01-30 | Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 22 PDB 声明：22-meric（22） 与蛋白数一致 |
链 K
1–56（56 aa）
|
未记录 | HEM PROTOPORPHYRIN IX CONTAINING FE × 6 FES FE2/S2 (INORGANIC) CLUSTER × 2 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION；pH 7.2；277 K；PEG 4000, ammonium acetate, potassium chloride, glyerol, DMG/SPC, MOPS, pH 7.2, VAPOR DIFFUSION, temperature 277K
|
分辨率 2.40 Å R-free 0.285 |
| 1NTZ Crystal Structure of Mitochondrial Cytochrome bc1 Complex Bound with Ubiquinone 提交 2003-01-30 | Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 22 PDB 声明：22-meric（22） 与蛋白数一致 |
链 K
1–56（56 aa）
|
未记录 | HEM PROTOPORPHYRIN IX CONTAINING FE × 6 UQ2 UBIQUINONE-2 × 4 FES FE2/S2 (INORGANIC) CLUSTER × 2 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION；pH 7.2；277 K；PEG 4000, ammonium acetate, potassium chloride, glycerol, DMG/SPC, MOPS, pH 7.2, VAPOR DIFFUSION, temperature 277K
|
分辨率 2.60 Å R-free 0.283 |
| 1NU1 Crystal Structure of Mitochondrial Cytochrome bc1 Complexed with 2-nonyl-4-hydroxyquinoline N-oxide (NQNO) 提交 2003-01-30 | Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 22 PDB 声明：22-meric（22） 与蛋白数一致 |
链 K
1–56（56 aa）
|
未记录 | HEM PROTOPORPHYRIN IX CONTAINING FE × 6 QNO 2-NONYL-4-HYDROXYQUINOLINE N-OXIDE × 2 FES FE2/S2 (INORGANIC) CLUSTER × 2 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION；pH 7.2；277 K；PEG 4000, ammonium acetate, potassium chloride, glycerol, DMG/SPC, MOPS, pH 7.2, VAPOR DIFFUSION, temperature 277K
|
分辨率 3.20 Å R-free 0.296 |
| 1QCR CRYSTAL STRUCTURE OF BOVINE MITOCHONDRIAL CYTOCHROME BC1 COMPLEX, ALPHA CARBON ATOMS ONLY 提交 1997-05-17 | Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 11 PDB 声明：undecameric（11） 与蛋白数一致 |
链 K
1–45（45 aa）
|
未记录 | HEM PROTOPORPHYRIN IX CONTAINING FE × 1 | X-RAY DIFFRACTION |
X-ray结晶条件
pH 7.2；pH 7.2
|
分辨率 2.70 Å R-free 0.375 |
| 1SQB Crystal Structure Analysis of Bovine Bc1 with Azoxystrobin 提交 2004-03-18 | Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 22 PDB 声明：22-meric（22） 与蛋白数一致 |
链 K
1–56（56 aa）
|
未记录 | HEM PROTOPORPHYRIN IX CONTAINING FE × 6 AZO METHYL (2Z)-2-(2-{[6-(2-CYANOPHENOXY)PYRIMIDIN-4-YL]OXY}PHENYL)-3-METHOXYACRYLATE × 2 FES FE2/S2 (INORGANIC) CLUSTER × 2 | X-RAY DIFFRACTION |
X-ray结晶条件
pH 7.2；277 K；20mM ammonium acetate, 20% glycerol, 12% PEG4000, 0.5M KCl, 0.1% diheptanoyl-phosphatidylcholine, pH 7.2, VAPOR DIFFUSION, SITTING DROP, temperature 277K, pH 7.20
|
分辨率 2.69 Å R-free 0.288 |
| 1SQP Crystal Structure Analysis of Bovine Bc1 with Myxothiazol 提交 2004-03-19 | Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 22 PDB 声明：22-meric（22） 与蛋白数一致 |
链 K
1–56（56 aa）
片段：subunit 11
|
未记录 | CDL CARDIOLIPIN × 6 PEE 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine × 6 HEC HEME C × 6 MYX (2Z,6E)-7-{2'-[(2E,4E)-1,6-DIMETHYLHEPTA-2,4-DIENYL]-2,4'-BI-1,3-THIAZOL-4-YL}-3,5-DIMETHOXY-4-METHYLHEPTA-2,6-DIENAMID E × 2 FES FE2/S2 (INORGANIC) CLUSTER × 2 PLX (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL × 2 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION；pH 7.2；277 K；20mM ammonium acetate, 20% glycerol, 12% PEG4000,
0.5M KCl, 0.1% diheptanoyl-phosphatidylcholine, pH 7.2, VAPOR DIFFUSION, temperature 277K
|
分辨率 2.70 Å R-free 0.314 |
| 1SQQ Crystal Structure Analysis of Bovine Bc1 with Methoxy Acrylate Stilbene (MOAS) 提交 2004-03-19 | Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 22 PDB 声明：22-meric（22） 与蛋白数一致 |
链 K
1–56（56 aa）
片段：subunit 11
|
未记录 | HEC HEME C × 6 UQ2 UBIQUINONE-2 × 2 OST METHYL (2Z)-3-METHOXY-2-{2-[(E)-2-PHENYLVINYL]PHENYL}ACRYLATE × 2 FES FE2/S2 (INORGANIC) CLUSTER × 2 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION；pH 7.2；277 K；20mM ammonium acetate, 20% glycerol, 12% PEG4000,
0.5M KCl, 0.1% diheptanoyl-phosphatidylcholine
, pH 7.2, VAPOR DIFFUSION, temperature 277K
|
分辨率 3.00 Å R-free 0.295 |
| 1SQV Crystal Structure Analysis of Bovine Bc1 with UHDBT 提交 2004-03-19 | Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 22 PDB 声明：22-meric（22） 与蛋白数一致 |
链 K
1–56（56 aa）
|
未记录 | HEC HEME C × 6 UHD 6-HYDROXY-5-UNDECYL-1,3-BENZOTHIAZOLE-4,7-DIONE × 2 UQ2 UBIQUINONE-2 × 2 FES FE2/S2 (INORGANIC) CLUSTER × 2 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION；pH 7.2；277 K；20mM ammonium acetate, 20% glycerol, 12% PEG4000,
0.5M KCl, 0.1% diheptanoyl-phosphatidylcholine, pH 7.2, VAPOR DIFFUSION, temperature 277K
|
分辨率 2.85 Å R-free 0.285 |
| 1SQX Crystal Structure Analysis of Bovine Bc1 with Stigmatellin A 提交 2004-03-21 | Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 22 PDB 声明：22-meric（22） 与蛋白数一致 |
链 K
1–56（56 aa）
片段：subunit 9
|
未记录 | UQ2 UBIQUINONE-2 × 2 HEC HEME C × 6 SMA STIGMATELLIN A × 2 FES FE2/S2 (INORGANIC) CLUSTER × 2 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION；pH 7.2；277 K；20mM ammonium acetate, 20% glycerol, 12% PEG4000,
0.5M KCl, 0.1% diheptanoyl-phosphatidylcholine
, pH 7.2, VAPOR DIFFUSION, temperature 277K
|
分辨率 2.60 Å R-free 0.281 |
| 2FYU Crystal structure of bovine heart mitochondrial bc1 with jg144 inhibitor 提交 2006-02-08 | Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 22 PDB 声明：22-meric（22） 与蛋白数一致 |
链 K
1–56（56 aa）
片段：subunit 11
|
未记录 | HEM PROTOPORPHYRIN IX CONTAINING FE × 6 FDN (5S)-3-ANILINO-5-(2,4-DIFLUOROPHENYL)-5-METHYL-1,3-OXAZOLIDINE-2,4-DIONE × 2 FES FE2/S2 (INORGANIC) CLUSTER × 2 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION, SITTING DROP；pH 7.2；277.2 K；50 mM MOPS 7.2pH, 20 mM Ammonium acetate, 20% glycerol.Incubation with 2-5 mol excess of JG144. Precipitant 12% PEG4000, 0.5 M KCl, 0.1% DHPC; Protein:PPT ratio 1:0.57, VAPOR DIFFUSION, SITTING DROP, temperature 277.2K
|
分辨率 2.26 Å R-free 0.283 |
| 2YBB Fitted model for bovine mitochondrial supercomplex I1III2IV1 by single particle cryo-EM (EMD-1876) 提交 2011-03-02 | Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 48 PDB 声明：48-meric（48） 与蛋白数一致 |
链 K
1–56（56 aa）
链 k
1–56（56 aa）
|
未记录 | SF4 IRON/SULFUR CLUSTER × 7 FMN FLAVIN MONONUCLEOTIDE × 1 NAI 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE × 1 MG MAGNESIUM ION × 7 FES FE2/S2 (INORGANIC) CLUSTER × 4 CA CALCIUM ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 5 SMA STIGMATELLIN A × 2 UQ1 UBIQUINONE-1 × 2 HEC HEME C × 2 CDL CARDIOLIPIN × 4 HEA HEME-A × 2 CU COPPER (II) ION × 3 ZN ZINC ION × 1 | ELECTRON MICROSCOPY |
cryo-EM缓冲液
10 MM KCL, 15 MM HEPES, RESIDUAL TREHALOSE；pH 7.7；10 MM KCL, 15 MM HEPES, RESIDUAL TREHALOSE
cryo-EM玻璃化条件
冷冻剂 ETHANE；VITRIFICATION 1 -- CRYOGEN- ETHANE, HUMIDITY- 70, TEMPERATURE- 95, INSTRUMENT- CUSTOM-MADE HAND PLUNGER, METHOD- ONE- SIDED BLOTTING FOR 26 - 30 SECONDS BEFORE PLUNGING, DETAILS- SAMPLE WAS ADSORBED TO CARBON FILM FOR 30 SECONDS BEFORE BLOTTING
|
分辨率 19.00 Å |
| 5GPN Architecture of mammalian respirasome 提交 2016-08-03 | Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 84 PDB 声明：84-meric（84） 与蛋白数一致 |
链 K
1–56（56 aa）
链 V
1–56（56 aa）
|
未记录 | HEM PROTOPORPHYRIN IX CONTAINING FE × 4 HEC HEME C × 2 FES FE2/S2 (INORGANIC) CLUSTER × 4 SF4 IRON/SULFUR CLUSTER × 6 FMN FLAVIN MONONUCLEOTIDE × 1 NDP NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE × 1 ZN ZINC ION × 1 HEA HEME-A × 2 CU COPPER (II) ION × 3 MG MAGNESIUM ION × 1 | ELECTRON MICROSCOPY |
cryo-EM缓冲液
pH 7.2
cryo-EM玻璃化条件
冷冻剂 NITROGEN
|
分辨率 5.40 Å |
| 5KLV Structure of bos taurus cytochrome bc1 with fenamidone inhibited 提交 2016-06-25 | Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 22 PDB 声明：22-meric（22） 与蛋白数一致 |
链 K
2–56（55 aa）
|
未记录 | 6PE 1,2-DIHEXANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE × 4 CDL CARDIOLIPIN × 6 GOL GLYCEROL × 6 HEM PROTOPORPHYRIN IX CONTAINING FE × 4 FNM (5S)-5-methyl-2-(methylsulfanyl)-5-phenyl-3-(phenylamino)-3,5-dihydro-4H-imidazol-4-one × 2 8PE (2R)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(tetradecanoyloxy)propyl octadecanoate × 2 CL CHLORIDE ION × 2 HEC HEME C × 2 PEF DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE × 2 FES FE2/S2 (INORGANIC) CLUSTER × 2 PX4 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE × 2 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION, SITTING DROP；pH 7.2；277 K；50 mM MOPS 7.2 pH, 20 mM Ammonium acetate, 20% glycerol. Incubation with 2-5 mol excess of Fenamidone. Precipitant 12% PEG4000, 0.5 M KCl, 0.1% DHPC; Protein:PPT ratio 1:0.57
|
分辨率 2.65 Å R-free 0.269 |
| 5LUF Cryo-EM of bovine respirasome 提交 2016-09-08 | Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 62 PDB 声明：62-meric（62） 与蛋白数一致 |
链 k
1–56（56 aa）
链 w
1–56（56 aa）
|
未记录 | HEM PROTOPORPHYRIN IX CONTAINING FE × 4 HEC HEME C × 2 FES FE2/S2 (INORGANIC) CLUSTER × 3 CU COPPER (II) ION × 3 MG MAGNESIUM ION × 1 HEA HEME-A × 2 ZN ZINC ION × 1 SF4 IRON/SULFUR CLUSTER × 6 | ELECTRON MICROSCOPY |
cryo-EM缓冲液
pH 7.7
cryo-EM玻璃化条件
冷冻剂 ETHANE；10 s blotting
|
分辨率 9.10 Å |
| 6NHG Rhodobacter sphaeroides Mitochondrial respiratory chain complex 提交 2018-12-21 | Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 22 PDB 声明：22-meric（22） 与蛋白数一致 |
链 K
2–56（55 aa）
|
未记录 | 6PE 1,2-DIHEXANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE × 4 CDL CARDIOLIPIN × 6 HEM PROTOPORPHYRIN IX CONTAINING FE × 4 AZO METHYL (2Z)-2-(2-{[6-(2-CYANOPHENOXY)PYRIMIDIN-4-YL]OXY}PHENYL)-3-METHOXYACRYLATE × 2 8PE (2R)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(tetradecanoyloxy)propyl octadecanoate × 2 HEC HEME C × 2 FES FE2/S2 (INORGANIC) CLUSTER × 2 MC3 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE × 2 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION, SITTING DROP；pH 7.2；277 K；50 mM MOPS 7.2 pH, 20 mM Ammonium acetate, 20% glycerol. Incubation with 2-5 mol excess of Azoxystrobin. Precipitant 12% PEG4000, 0.5 M KCl, 0.1% DHPC; Protein:PPT ratio 1:0.57
|
分辨率 2.80 Å R-free 0.289 |
| 7DGQ Activity optimized supercomplex state1 提交 2020-11-12 | Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 80 PDB 声明：80-meric（80） 与蛋白数一致 |
链 A4
1–56（56 aa）
链 t
1–56（56 aa）
|
未记录 | PC1 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE × 5 3PE 1,2-Distearoyl-sn-glycerophosphoethanolamine × 5 FES FE2/S2 (INORGANIC) CLUSTER × 3 CDL CARDIOLIPIN × 3 FMN FLAVIN MONONUCLEOTIDE × 1 SF4 IRON/SULFUR CLUSTER × 6 CU COPPER (II) ION × 3 HEA HEME-A × 2 MG MAGNESIUM ION × 1 ZN ZINC ION × 2 NAP NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 4 HEC HEME C × 2 UQ2 UBIQUINONE-2 × 1 | ELECTRON MICROSCOPY |
cryo-EM缓冲液
pH 7.4
cryo-EM玻璃化条件
冷冻剂 ETHANE
|
分辨率 5.00 Å |
| 7DGR Activity optimized supercomplex state2 提交 2020-11-12 | Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 80 PDB 声明：80-meric（80） 与蛋白数一致 |
链 A3
1–56（56 aa）
链 t
1–56（56 aa）
|
未记录 | FES FE2/S2 (INORGANIC) CLUSTER × 3 3PE 1,2-Distearoyl-sn-glycerophosphoethanolamine × 4 CDL CARDIOLIPIN × 3 PC1 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE × 5 FMN FLAVIN MONONUCLEOTIDE × 1 SF4 IRON/SULFUR CLUSTER × 6 ZN ZINC ION × 2 NAP NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 4 HEC HEME C × 2 HEA HEME-A × 2 CU COPPER (II) ION × 3 MG MAGNESIUM ION × 1 | ELECTRON MICROSCOPY |
cryo-EM缓冲液
pH 7.4
cryo-EM玻璃化条件
冷冻剂 ETHANE
|
分辨率 4.60 Å |
| 7DGS Activity optimized supercomplex state3 提交 2020-11-12 | Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 80 PDB 声明：80-meric（80） 与蛋白数一致 |
链 A3
1–56（56 aa）
链 t
1–56（56 aa）
|
未记录 | FES FE2/S2 (INORGANIC) CLUSTER × 3 CDL CARDIOLIPIN × 3 3PE 1,2-Distearoyl-sn-glycerophosphoethanolamine × 5 PC1 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE × 5 FMN FLAVIN MONONUCLEOTIDE × 1 SF4 IRON/SULFUR CLUSTER × 6 ZN ZINC ION × 2 NAP NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 4 HEC HEME C × 2 HEA HEME-A × 2 CU COPPER (II) ION × 3 MG MAGNESIUM ION × 1 | ELECTRON MICROSCOPY |
cryo-EM缓冲液
pH 7.4
cryo-EM玻璃化条件
冷冻剂 ETHANE
|
分辨率 7.80 Å |
| 7DKF Activity optimized supercomplex state4 提交 2020-11-24 | Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 80 PDB 声明：80-meric（80） 与蛋白数一致 |
链 K1
1–56（56 aa）
链 W1
1–56（56 aa）
|
未记录 | HEM PROTOPORPHYRIN IX CONTAINING FE × 4 HEC HEME C × 2 FES FE2/S2 (INORGANIC) CLUSTER × 3 3PE 1,2-Distearoyl-sn-glycerophosphoethanolamine × 3 CDL CARDIOLIPIN × 1 FMN FLAVIN MONONUCLEOTIDE × 1 SF4 IRON/SULFUR CLUSTER × 6 ZN ZINC ION × 2 NAP NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE × 1 PC1 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE × 2 HEA HEME-A × 2 CU COPPER (II) ION × 3 MG MAGNESIUM ION × 1 | ELECTRON MICROSCOPY |
cryo-EM缓冲液
pH 7.4
cryo-EM玻璃化条件
冷冻剂 ETHANE
|
分辨率 8.30 Å |
| 7TAY Bos Taurus Mitochondrial BC1 in complex with Pyramoxadone 提交 2021-12-21 | Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 22 PDB 声明：22-meric（22） 与蛋白数一致 |
链 K
1–56（56 aa）
|
未记录 | 6PE 1,2-DIHEXANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE × 4 CDL CARDIOLIPIN × 6 HEM PROTOPORPHYRIN IX CONTAINING FE × 4 PQU (5S)-3-anilino-5-methyl-5-(6-phenoxypyridin-3-yl)-1,3-oxazolidine-2,4-dione × 2 8PE (2R)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(tetradecanoyloxy)propyl octadecanoate × 2 PEF DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE × 2 CL CHLORIDE ION × 2 HEC HEME C × 2 FES FE2/S2 (INORGANIC) CLUSTER × 2 PX4 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE × 2 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION, SITTING DROP；277 K；50 mM MOPS 7.2 pH, 20 mM Ammonium acetate, 20% glycerol. Incubation with 5 molar excess of pyramoxadone. Precipitant 12% PEG4000, 0.5 M KCL, 0.1% DHPC.
|
分辨率 2.95 Å R-free 0.258 |
| 7TZ6 Structure of mitochondrial bc1 in complex with ck-2-68 提交 2022-02-15 | Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 22 PDB 声明：22-meric（22） 与蛋白数一致 |
链 K
1–56（56 aa）
链 X
1–56（56 aa）
|
未记录 | HEM PROTOPORPHYRIN IX CONTAINING FE × 4 JHB 7-chloranyl-3-methyl-2-[4-[[4-(trifluoromethyloxy)phenyl]methyl]phenyl]-1~{H}-quinolin-4-one × 2 HEC HEME C × 2 FES FE2/S2 (INORGANIC) CLUSTER × 2 | ELECTRON MICROSCOPY |
cryo-EM缓冲液
pH 7.5
cryo-EM玻璃化条件
冷冻剂 ETHANE
|
分辨率 2.88 Å |
| 8P65 Cytochrome bc1 complex (Bos taurus) 提交 2023-05-25 | Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 22 PDB 声明：22-meric（22） 与蛋白数一致 |
链 K
1–49（49 aa）
链 X
1–49（49 aa）
|
未记录 | HEM PROTOPORPHYRIN IX CONTAINING FE × 4 HEC HEME C × 2 FES FE2/S2 (INORGANIC) CLUSTER × 2 | ELECTRON MICROSCOPY |
cryo-EM缓冲液
pH 7.5
cryo-EM玻璃化条件
冷冻剂 ETHANE；Blot time of 4s with blot force of -3
|
分辨率 3.00 Å |
| 9GCX Crystal structure of bovine Cytochrome bc1 in complex with inhibitor F8 提交 2024-08-03 | Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 22 PDB 声明：22-meric（22） 与蛋白数一致 |
链 K
1–56（56 aa）
|
未记录 | LOP (1R)-2-{[(R)-(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(DODECANOYLOXY)METHYL]ETHYL (9Z)-OCTADEC-9-ENOATE × 12 CDL CARDIOLIPIN × 6 HEM PROTOPORPHYRIN IX CONTAINING FE × 4 A1IKG 2-methyl-3-(4-(4-(trifluoromethoxy)phenoxy)phenyl)-1,5,7,8-tetrahydro-4H-pyrano[4,3-b]pyridin-4-one × 2 LMT DODECYL-BETA-D-MALTOSIDE × 2 HEC HEME C × 2 FES FE2/S2 (INORGANIC) CLUSTER × 2 PSC (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE × 2 SO4 SULFATE ION × 6 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION, HANGING DROP；pH 6.8；277 K；50 mM KPi pH 6.8, 100 mM NaCl, 3 mM NaN3, 10-20% PEG4000
|
分辨率 3.52 Å R-free 0.241 |
| 9W2X Cryo-EM structure of complex III on the bovine heart submitochondrial particles, III-1 提交 2025-07-28 | Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 22 PDB 声明：22-meric（22） 与蛋白数一致 |
链 K
2–53（52 aa）
链 X
2–53（52 aa）
|
未记录 | HEM PROTOPORPHYRIN IX CONTAINING FE × 4 HEC HEME C × 2 FES FE2/S2 (INORGANIC) CLUSTER × 2 | ELECTRON MICROSCOPY |
cryo-EM缓冲液
pH 7.5
cryo-EM玻璃化条件
冷冻剂 ETHANE
|
分辨率 2.20 Å |
| 9W2Y Cryo-EM structure of complex III on the bovine heart submitochondrial particles, III-2 提交 2025-07-28 | Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 22 PDB 声明：22-meric（22） 与蛋白数一致 |
链 K
2–53（52 aa）
链 V
2–53（52 aa）
|
未记录 | HEM PROTOPORPHYRIN IX CONTAINING FE × 4 HEC HEME C × 2 FES FE2/S2 (INORGANIC) CLUSTER × 2 | ELECTRON MICROSCOPY |
cryo-EM缓冲液
pH 7.5
cryo-EM玻璃化条件
冷冻剂 ETHANE
|
分辨率 2.40 Å |