1i97

CRYSTAL STRUCTURE OF THE 30S RIBOSOMAL SUBUNIT FROM THERMUS THERMOPHILUS IN COMPLEX WITH TETRACYCLINE

Method: X-RAY DIFFRACTION

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1. Protein Identity and Related Structures Protein Identity & Related Structures

30S RIBOSOMAL PROTEIN S4

OrganismNot specified

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 20 RNA 1	16S RRNA × 1 30S RIBOSOMAL PROTEIN S2 × 1 30S RIBOSOMAL PROTEIN S3 × 1 30S RIBOSOMAL PROTEIN S5 × 1 （P27152） 30S RIBOSOMAL PROTEIN S6 × 1 （P23370） 30S RIBOSOMAL PROTEIN S7 × 1 （P17291） 30S RIBOSOMAL PROTEIN S8 × 1 （P24319） 30S RIBOSOMAL PROTEIN S9 × 1 30S RIBOSOMAL PROTEIN S10 × 1 （P80375） 30S RIBOSOMAL PROTEIN S11 × 1 30S RIBOSOMAL PROTEIN S12 × 1 （P17293） 30S RIBOSOMAL PROTEIN S13 × 1 30S RIBOSOMAL PROTEIN S14 × 1 （P24320） 30S RIBOSOMAL PROTEIN S15 × 1 （P80378） 30S RIBOSOMAL PROTEIN S16 × 1 30S RIBOSOMAL PROTEIN S17 × 1 （P24321） 30S RIBOSOMAL PROTEIN S18 × 1 30S RIBOSOMAL PROTEIN S19 × 1 （P80381） 30S RIBOSOMAL PROTEIN S20 × 1 30S RIBOSOMAL PROTEIN THX × 1 MAGNESIUM ION × 75 OCTADECATUNGSTENYL DIPHOSPHATE × 14 TETRACYCLINE × 6 ZINC ION × 2	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RS4_THETH
Isoform	—
PDB entities	4
Chains and sequence ranges	Author chain D； PDBConstruct 1–208； UniProt 1–208

30S RIBOSOMAL PROTEIN S5

OrganismNot specified

UniProt P27152

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 20 RNA 1	16S RRNA × 1 30S RIBOSOMAL PROTEIN S2 × 1 30S RIBOSOMAL PROTEIN S3 × 1 30S RIBOSOMAL PROTEIN S4 × 1 （P80373） 30S RIBOSOMAL PROTEIN S6 × 1 （P23370） 30S RIBOSOMAL PROTEIN S7 × 1 （P17291） 30S RIBOSOMAL PROTEIN S8 × 1 （P24319） 30S RIBOSOMAL PROTEIN S9 × 1 30S RIBOSOMAL PROTEIN S10 × 1 （P80375） 30S RIBOSOMAL PROTEIN S11 × 1 30S RIBOSOMAL PROTEIN S12 × 1 （P17293） 30S RIBOSOMAL PROTEIN S13 × 1 30S RIBOSOMAL PROTEIN S14 × 1 （P24320） 30S RIBOSOMAL PROTEIN S15 × 1 （P80378） 30S RIBOSOMAL PROTEIN S16 × 1 30S RIBOSOMAL PROTEIN S17 × 1 （P24321） 30S RIBOSOMAL PROTEIN S18 × 1 30S RIBOSOMAL PROTEIN S19 × 1 （P80381） 30S RIBOSOMAL PROTEIN S20 × 1 30S RIBOSOMAL PROTEIN THX × 1 MAGNESIUM ION × 75 OCTADECATUNGSTENYL DIPHOSPHATE × 14 TETRACYCLINE × 6 ZINC ION × 2	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RS5_THETH
Isoform	—
PDB entities	5
Chains and sequence ranges	Author chain E； PDBConstruct 1–161； UniProt 1–161

30S RIBOSOMAL PROTEIN S6

OrganismNot specified

UniProt P23370

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 20 RNA 1	16S RRNA × 1 30S RIBOSOMAL PROTEIN S2 × 1 30S RIBOSOMAL PROTEIN S3 × 1 30S RIBOSOMAL PROTEIN S4 × 1 （P80373） 30S RIBOSOMAL PROTEIN S5 × 1 （P27152） 30S RIBOSOMAL PROTEIN S7 × 1 （P17291） 30S RIBOSOMAL PROTEIN S8 × 1 （P24319） 30S RIBOSOMAL PROTEIN S9 × 1 30S RIBOSOMAL PROTEIN S10 × 1 （P80375） 30S RIBOSOMAL PROTEIN S11 × 1 30S RIBOSOMAL PROTEIN S12 × 1 （P17293） 30S RIBOSOMAL PROTEIN S13 × 1 30S RIBOSOMAL PROTEIN S14 × 1 （P24320） 30S RIBOSOMAL PROTEIN S15 × 1 （P80378） 30S RIBOSOMAL PROTEIN S16 × 1 30S RIBOSOMAL PROTEIN S17 × 1 （P24321） 30S RIBOSOMAL PROTEIN S18 × 1 30S RIBOSOMAL PROTEIN S19 × 1 （P80381） 30S RIBOSOMAL PROTEIN S20 × 1 30S RIBOSOMAL PROTEIN THX × 1 MAGNESIUM ION × 75 OCTADECATUNGSTENYL DIPHOSPHATE × 14 TETRACYCLINE × 6 ZINC ION × 2	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RS6_THETH
Isoform	—
PDB entities	6
Chains and sequence ranges	Author chain F； PDBConstruct 1–101； UniProt 1–101

30S RIBOSOMAL PROTEIN S7

OrganismNot specified

UniProt P17291

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 20 RNA 1	16S RRNA × 1 30S RIBOSOMAL PROTEIN S2 × 1 30S RIBOSOMAL PROTEIN S3 × 1 30S RIBOSOMAL PROTEIN S4 × 1 （P80373） 30S RIBOSOMAL PROTEIN S5 × 1 （P27152） 30S RIBOSOMAL PROTEIN S6 × 1 （P23370） 30S RIBOSOMAL PROTEIN S8 × 1 （P24319） 30S RIBOSOMAL PROTEIN S9 × 1 30S RIBOSOMAL PROTEIN S10 × 1 （P80375） 30S RIBOSOMAL PROTEIN S11 × 1 30S RIBOSOMAL PROTEIN S12 × 1 （P17293） 30S RIBOSOMAL PROTEIN S13 × 1 30S RIBOSOMAL PROTEIN S14 × 1 （P24320） 30S RIBOSOMAL PROTEIN S15 × 1 （P80378） 30S RIBOSOMAL PROTEIN S16 × 1 30S RIBOSOMAL PROTEIN S17 × 1 （P24321） 30S RIBOSOMAL PROTEIN S18 × 1 30S RIBOSOMAL PROTEIN S19 × 1 （P80381） 30S RIBOSOMAL PROTEIN S20 × 1 30S RIBOSOMAL PROTEIN THX × 1 MAGNESIUM ION × 75 OCTADECATUNGSTENYL DIPHOSPHATE × 14 TETRACYCLINE × 6 ZINC ION × 2	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	P17291
Isoform	—
PDB entities	7
Chains and sequence ranges	Author chain G； PDBConstruct 1–155； UniProt 1–155

30S RIBOSOMAL PROTEIN S8

OrganismNot specified

UniProt P24319

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 20 RNA 1	16S RRNA × 1 30S RIBOSOMAL PROTEIN S2 × 1 30S RIBOSOMAL PROTEIN S3 × 1 30S RIBOSOMAL PROTEIN S4 × 1 （P80373） 30S RIBOSOMAL PROTEIN S5 × 1 （P27152） 30S RIBOSOMAL PROTEIN S6 × 1 （P23370） 30S RIBOSOMAL PROTEIN S7 × 1 （P17291） 30S RIBOSOMAL PROTEIN S9 × 1 30S RIBOSOMAL PROTEIN S10 × 1 （P80375） 30S RIBOSOMAL PROTEIN S11 × 1 30S RIBOSOMAL PROTEIN S12 × 1 （P17293） 30S RIBOSOMAL PROTEIN S13 × 1 30S RIBOSOMAL PROTEIN S14 × 1 （P24320） 30S RIBOSOMAL PROTEIN S15 × 1 （P80378） 30S RIBOSOMAL PROTEIN S16 × 1 30S RIBOSOMAL PROTEIN S17 × 1 （P24321） 30S RIBOSOMAL PROTEIN S18 × 1 30S RIBOSOMAL PROTEIN S19 × 1 （P80381） 30S RIBOSOMAL PROTEIN S20 × 1 30S RIBOSOMAL PROTEIN THX × 1 MAGNESIUM ION × 75 OCTADECATUNGSTENYL DIPHOSPHATE × 14 TETRACYCLINE × 6 ZINC ION × 2	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RS8_THETH
Isoform	—
PDB entities	8
Chains and sequence ranges	Author chain H； PDBConstruct 1–138； UniProt 1–138

30S RIBOSOMAL PROTEIN S10

OrganismNot specified

UniProt P80375

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 20 RNA 1	16S RRNA × 1 30S RIBOSOMAL PROTEIN S2 × 1 30S RIBOSOMAL PROTEIN S3 × 1 30S RIBOSOMAL PROTEIN S4 × 1 （P80373） 30S RIBOSOMAL PROTEIN S5 × 1 （P27152） 30S RIBOSOMAL PROTEIN S6 × 1 （P23370） 30S RIBOSOMAL PROTEIN S7 × 1 （P17291） 30S RIBOSOMAL PROTEIN S8 × 1 （P24319） 30S RIBOSOMAL PROTEIN S9 × 1 30S RIBOSOMAL PROTEIN S11 × 1 30S RIBOSOMAL PROTEIN S12 × 1 （P17293） 30S RIBOSOMAL PROTEIN S13 × 1 30S RIBOSOMAL PROTEIN S14 × 1 （P24320） 30S RIBOSOMAL PROTEIN S15 × 1 （P80378） 30S RIBOSOMAL PROTEIN S16 × 1 30S RIBOSOMAL PROTEIN S17 × 1 （P24321） 30S RIBOSOMAL PROTEIN S18 × 1 30S RIBOSOMAL PROTEIN S19 × 1 （P80381） 30S RIBOSOMAL PROTEIN S20 × 1 30S RIBOSOMAL PROTEIN THX × 1 MAGNESIUM ION × 75 OCTADECATUNGSTENYL DIPHOSPHATE × 14 TETRACYCLINE × 6 ZINC ION × 2	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RS10_THETH
Isoform	—
PDB entities	10
Chains and sequence ranges	Author chain J； PDBConstruct 1–104； UniProt 1–104

30S RIBOSOMAL PROTEIN S12

OrganismNot specified

UniProt P17293

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 20 RNA 1	16S RRNA × 1 30S RIBOSOMAL PROTEIN S2 × 1 30S RIBOSOMAL PROTEIN S3 × 1 30S RIBOSOMAL PROTEIN S4 × 1 （P80373） 30S RIBOSOMAL PROTEIN S5 × 1 （P27152） 30S RIBOSOMAL PROTEIN S6 × 1 （P23370） 30S RIBOSOMAL PROTEIN S7 × 1 （P17291） 30S RIBOSOMAL PROTEIN S8 × 1 （P24319） 30S RIBOSOMAL PROTEIN S9 × 1 30S RIBOSOMAL PROTEIN S10 × 1 （P80375） 30S RIBOSOMAL PROTEIN S11 × 1 30S RIBOSOMAL PROTEIN S13 × 1 30S RIBOSOMAL PROTEIN S14 × 1 （P24320） 30S RIBOSOMAL PROTEIN S15 × 1 （P80378） 30S RIBOSOMAL PROTEIN S16 × 1 30S RIBOSOMAL PROTEIN S17 × 1 （P24321） 30S RIBOSOMAL PROTEIN S18 × 1 30S RIBOSOMAL PROTEIN S19 × 1 （P80381） 30S RIBOSOMAL PROTEIN S20 × 1 30S RIBOSOMAL PROTEIN THX × 1 MAGNESIUM ION × 75 OCTADECATUNGSTENYL DIPHOSPHATE × 14 TETRACYCLINE × 6 ZINC ION × 2	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RS12_THETH
Isoform	—
PDB entities	12
Chains and sequence ranges	Author chain L； PDBConstruct 1–131； UniProt 5–135

30S RIBOSOMAL PROTEIN S14

OrganismNot specified

UniProt P24320

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 20 RNA 1	16S RRNA × 1 30S RIBOSOMAL PROTEIN S2 × 1 30S RIBOSOMAL PROTEIN S3 × 1 30S RIBOSOMAL PROTEIN S4 × 1 （P80373） 30S RIBOSOMAL PROTEIN S5 × 1 （P27152） 30S RIBOSOMAL PROTEIN S6 × 1 （P23370） 30S RIBOSOMAL PROTEIN S7 × 1 （P17291） 30S RIBOSOMAL PROTEIN S8 × 1 （P24319） 30S RIBOSOMAL PROTEIN S9 × 1 30S RIBOSOMAL PROTEIN S10 × 1 （P80375） 30S RIBOSOMAL PROTEIN S11 × 1 30S RIBOSOMAL PROTEIN S12 × 1 （P17293） 30S RIBOSOMAL PROTEIN S13 × 1 30S RIBOSOMAL PROTEIN S15 × 1 （P80378） 30S RIBOSOMAL PROTEIN S16 × 1 30S RIBOSOMAL PROTEIN S17 × 1 （P24321） 30S RIBOSOMAL PROTEIN S18 × 1 30S RIBOSOMAL PROTEIN S19 × 1 （P80381） 30S RIBOSOMAL PROTEIN S20 × 1 30S RIBOSOMAL PROTEIN THX × 1 MAGNESIUM ION × 75 OCTADECATUNGSTENYL DIPHOSPHATE × 14 TETRACYCLINE × 6 ZINC ION × 2	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RS14_THETH
Isoform	—
PDB entities	14
Chains and sequence ranges	Author chain N； PDBConstruct 1–60； UniProt 1–60

30S RIBOSOMAL PROTEIN S15

OrganismNot specified

UniProt P80378

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 20 RNA 1	16S RRNA × 1 30S RIBOSOMAL PROTEIN S2 × 1 30S RIBOSOMAL PROTEIN S3 × 1 30S RIBOSOMAL PROTEIN S4 × 1 （P80373） 30S RIBOSOMAL PROTEIN S5 × 1 （P27152） 30S RIBOSOMAL PROTEIN S6 × 1 （P23370） 30S RIBOSOMAL PROTEIN S7 × 1 （P17291） 30S RIBOSOMAL PROTEIN S8 × 1 （P24319） 30S RIBOSOMAL PROTEIN S9 × 1 30S RIBOSOMAL PROTEIN S10 × 1 （P80375） 30S RIBOSOMAL PROTEIN S11 × 1 30S RIBOSOMAL PROTEIN S12 × 1 （P17293） 30S RIBOSOMAL PROTEIN S13 × 1 30S RIBOSOMAL PROTEIN S14 × 1 （P24320） 30S RIBOSOMAL PROTEIN S16 × 1 30S RIBOSOMAL PROTEIN S17 × 1 （P24321） 30S RIBOSOMAL PROTEIN S18 × 1 30S RIBOSOMAL PROTEIN S19 × 1 （P80381） 30S RIBOSOMAL PROTEIN S20 × 1 30S RIBOSOMAL PROTEIN THX × 1 MAGNESIUM ION × 75 OCTADECATUNGSTENYL DIPHOSPHATE × 14 TETRACYCLINE × 6 ZINC ION × 2	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RS15_THETH
Isoform	—
PDB entities	15
Chains and sequence ranges	Author chain O； PDBConstruct 1–88； UniProt 1–88

30S RIBOSOMAL PROTEIN S17

OrganismNot specified

UniProt P24321

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 20 RNA 1	16S RRNA × 1 30S RIBOSOMAL PROTEIN S2 × 1 30S RIBOSOMAL PROTEIN S3 × 1 30S RIBOSOMAL PROTEIN S4 × 1 （P80373） 30S RIBOSOMAL PROTEIN S5 × 1 （P27152） 30S RIBOSOMAL PROTEIN S6 × 1 （P23370） 30S RIBOSOMAL PROTEIN S7 × 1 （P17291） 30S RIBOSOMAL PROTEIN S8 × 1 （P24319） 30S RIBOSOMAL PROTEIN S9 × 1 30S RIBOSOMAL PROTEIN S10 × 1 （P80375） 30S RIBOSOMAL PROTEIN S11 × 1 30S RIBOSOMAL PROTEIN S12 × 1 （P17293） 30S RIBOSOMAL PROTEIN S13 × 1 30S RIBOSOMAL PROTEIN S14 × 1 （P24320） 30S RIBOSOMAL PROTEIN S15 × 1 （P80378） 30S RIBOSOMAL PROTEIN S16 × 1 30S RIBOSOMAL PROTEIN S18 × 1 30S RIBOSOMAL PROTEIN S19 × 1 （P80381） 30S RIBOSOMAL PROTEIN S20 × 1 30S RIBOSOMAL PROTEIN THX × 1 MAGNESIUM ION × 75 OCTADECATUNGSTENYL DIPHOSPHATE × 14 TETRACYCLINE × 6 ZINC ION × 2	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RS17_THETH
Isoform	—
PDB entities	17
Chains and sequence ranges	Author chain Q； PDBConstruct 1–104； UniProt 1–104

30S RIBOSOMAL PROTEIN S19

OrganismNot specified

UniProt P80381

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 20 RNA 1	16S RRNA × 1 30S RIBOSOMAL PROTEIN S2 × 1 30S RIBOSOMAL PROTEIN S3 × 1 30S RIBOSOMAL PROTEIN S4 × 1 （P80373） 30S RIBOSOMAL PROTEIN S5 × 1 （P27152） 30S RIBOSOMAL PROTEIN S6 × 1 （P23370） 30S RIBOSOMAL PROTEIN S7 × 1 （P17291） 30S RIBOSOMAL PROTEIN S8 × 1 （P24319） 30S RIBOSOMAL PROTEIN S9 × 1 30S RIBOSOMAL PROTEIN S10 × 1 （P80375） 30S RIBOSOMAL PROTEIN S11 × 1 30S RIBOSOMAL PROTEIN S12 × 1 （P17293） 30S RIBOSOMAL PROTEIN S13 × 1 30S RIBOSOMAL PROTEIN S14 × 1 （P24320） 30S RIBOSOMAL PROTEIN S15 × 1 （P80378） 30S RIBOSOMAL PROTEIN S16 × 1 30S RIBOSOMAL PROTEIN S17 × 1 （P24321） 30S RIBOSOMAL PROTEIN S18 × 1 30S RIBOSOMAL PROTEIN S20 × 1 30S RIBOSOMAL PROTEIN THX × 1 MAGNESIUM ION × 75 OCTADECATUNGSTENYL DIPHOSPHATE × 14 TETRACYCLINE × 6 ZINC ION × 2	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RS19_THETH
Isoform	—
PDB entities	19
Chains and sequence ranges	Author chain S； PDBConstruct 1–92； UniProt 1–92

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id	1i97
Deposition date deposition_date	2001-03-18
Structure title title	CRYSTAL STRUCTURE OF THE 30S RIBOSOMAL SUBUNIT FROM THERMUS THERMOPHILUS IN COMPLEX WITH TETRACYCLINE
Keywords keywords	30S ribosome, antibiotics, tetracycline, RIBOSOME; RIBOSOME
Experimental Method method	X-RAY DIFFRACTION

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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

1i97__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

1i97__assembly_1__model_1 | I(q)

100 plotted points; both axes use logarithmic scales.

1i97__assembly_1__model_1 | P(r) · Pending

P(r) will be calculated and displayed separately for the same assembly/model.

Rg（Guinier）	66.17 Å
Rg (electron density)	66.91 Å
Total Rg	68.37 Å
Atom count	33951
Residues	1514
Excluded volume	821910 Å³
Maximum q	0.500 Å⁻¹

Assembly	Model	Structure unit	Oligomeric description	Status	CRYSOL	Actions
1	1	`1i97__assembly_1__model_1`	21-meric （21）	Success	4.1.3-1-20251215 (887e7ef)	View Download

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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (25)

Entity 1 Entity 1 polymer

Description description	16S RRNA
Molecular weight formula_weight	491510.9 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polyribonucleotide
Chain IDs strand_id	A
Atom count atom_count	36361

UGUUGGAGAGUUUGAUCCUGGCUCAGGGUGAACGCUGGCGGCGUGCCUAAGACAUGCAAGUCGUGCGGGCCGCGGGGUUUUACUCCGUGGUCAGCGGCGGACGGGUGAGUAACGCGUGGGUGACCUACCCGGAAGAGGGGGACAACCCGGGGAAACUCGGGCUAAUCCCCCAUGUGGACCCGCCCCUUGGGGUGUGUCCAAAGGGCUUUGCCCGCUUCCGGAUGGGCCCGCGUCCCAUCAGCUAGUUGGUGGGGUAAUGGCCCACCAAGGCGACGACGGGUAGCCGGUCUGAGAGGAUGGCCGGCCACAGGGGCACUGAGACACGGGCCCCACUCCUACGGGAGGCAGCAGUUAGGAAUCUUCCGCAAUGGGCGCAAGCCUGACGGAGCGACGCCGCUUGGAGGAAGAAGCCCUUCGGGGUGUAAACUCCUGAACCCGGGACGAAACCCCCGACGAGGGGACUGACGGUACCGGGGUAAUAGCGCCGGCCAACUCCGUGCCAGCAGCCGCGGUAAUACGGAGGGCGCGAGCGUUACCCGGAUUCACUGGGCGUAAAGGGCGUGUAGGCGGCCUGGGGCGUCCCAUGUGAAAGACCACGGCUCAACCGUGGGGGAGCGUGGGAUACGCUCAGGCUAGACGGUGGGAGAGGGUGGUGGAAUUCCCGGAGUAGCGGUGAAAUGCGCAGAUACCGGGAGGAACGCCGAUGGCGAAGGCAGCCACCUGGUCCACCCGUGACGCUGAGGCGCGAAAGCGUGGGGAGCAAACCGGAUUAGAUACCCGGGUAGUCCACGCCCUAAACGAUGCGCGCUAGGUCUCUGGGUCUCCUGGGGGCCGAAGCUAACGCGUUAAGCGCGCCGCCUGGGGAGUACGGCCGCAAGGCUGAAACUCAAAGGAAUUGACGGGGGCCCGCACAAGCGGUGGAGCAUGUGGUUUAAUUCGAAGCAACGCGAAGAACCUUACCAGGCCUUGACAUGCUAGGGAACCCGGGUGAAAGCCUGGGGUGCCCCGCGAGGGGAGCCCUAGCACAGGUGCUGCAUGGCCGUCGUCAGCUCGUGCCGUGAGGUGUUGGGUUAAGUCCCGCAACGAGCGCAACCCCCGCCGUUAGUUGCCAGCGGUUCGGCCGGGCACUCUAACGGGACUGCCCGCGAAAGCGGGAGGAAGGAGGGGACGACGUCUGGUCAGCAUGGCCCUUACGGCCUGGGCGACACACGUGCUACAAUGCCCACUACAAAGCGAUGCCACCCGGCAACGGGGAGCUAAUCGCAAAAAGGUGGGCCCAGUUCGGAUUGGGGUCUGCAACCCGACCCCAUGAAGCCGGAAUCGCUAGUAAUCGCGGAUCAGCCAUGCCGCGGUGAAUACGUUCCCGGGCCUUGUACACACCGCCCGUCACGCCAUGGGAGCGGGCUCUACCCGAAGUCGCCGGGAGCCUACGGGCAGGCGCCGAGGGUAGGGCCCGUGACUGGGGCGAAGUCGUAACAAGGUAGCUGUACCGGAAGGUGCGGCUGGAUCACCUC

Entity 2 Entity 2 polymer

Description description	30S RIBOSOMAL PROTEIN S2
Molecular weight formula_weight	29186.5 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	B

PVEITVKELLEAGVHFGHERKRWNPKFARYIYAERNGIHIIDLQKTMEELERTFRFIEDLAMRGGTILFVGTKKQAQDIVRMEAERAGMPYVNQRWLGGMLTNFKTISQRVHRLEELEALFASPEIEERPKKEQVRLKHELERLQKYLSGFRLLKRLPDAIFVVDPTKEAIAVREARKLFIPVIALADTDSDPDLVDYIIPGNDDAIRSIQLILSRAVDLIIQARGGVVEPSPSYALVQEAEATETPEGESEVEA

Entity 3 Entity 3 polymer

Description description	30S RIBOSOMAL PROTEIN S3
Molecular weight formula_weight	26619.9 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	C

GNKIHPIGFRLGITRDWESRWYAGKKQYRHLLLEDQRIRGLLEKELYSAGLARVDIERAADNVAVTVHVAKPGVVIGRGGERIRVLREELAKLTGKNVALNVQEVQNPNLSAPLVAQRVAEQIERRFAVRRAIKQAVQRVMESGAKGAKVIVSGRIGGAEQARTEWAAQGRVPLHTLRANIDYGFALARTTYGVLGVKAYIFLGEVIGGQKPKARPELPKAEERPRRRRPAVRVKKEE

Entity 4 Entity 4 polymer

Description description	30S RIBOSOMAL PROTEIN S4
Molecular weight formula_weight	24242.3 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	D

GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQLVIEFYSR

Entity 5 Entity 5 polymer

Description description	30S RIBOSOMAL PROTEIN S5
Molecular weight formula_weight	17452.2 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	E

PETDFEEKMILIRRTARMQAGGRRFRFGALVVVGDRQGRVGLGFGKAPEVPLAVQKAGYYARRNMVEVPLQNGTIPHEIEVEFGASKIVLKPAAPGTGVIAGAVPRAILELAGVTDILTKELGSRNPINIAYATMEALRQLRTKADVERLRKGEAHAQAQG

Entity 6 Entity 6 polymer

Description description	30S RIBOSOMAL PROTEIN S6
Molecular weight formula_weight	11988.8 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	F

MRRYEVNIVLNPNLDQSQLALEKEIIQRALENYGARVEKVEELGLRRLAYPIAKDPQGYFLWYQVEMPEDRVNDLARELRIRDNVRRVMVVKSQEPFLANA

Entity 7 Entity 7 polymer

Description description	30S RIBOSOMAL PROTEIN S7
Molecular weight formula_weight	17919.8 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	G

ARRRRAEVRQLQPDLVYGDVLVTAFINKIMRDGKKNLAARIFYDACKIIQEKTGQEPLKVFKQAVENVKPRMEVRSRRVGGANYQVPMEVSPRRQQSLALRWLVQAANQRPERRAAVRIAHELMDAAEGKGGAVKKKEDVERMAEANRAYAHYRW

Entity 8 Entity 8 polymer

Description description	30S RIBOSOMAL PROTEIN S8
Molecular weight formula_weight	15886.7 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	H

MLTDPIADMLTRIRNATRVYKESTEVPASRFKEEILKILAREGFIKGYERVEVDGKPYLRIHLKYGPRRQGPDPRPEQVIKHIRRISRPGRRVYVGVKEIPRVRRGLGIAILSTPKGVLTDREARKLGVGGELICEVW

Entity 9 Entity 9 polymer

Description description	30S RIBOSOMAL PROTEIN S9
Molecular weight formula_weight	14429.7 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	I

MEQYYGTGRRKEAVARVFLRPGNGKVTVNGQDFNEYFQGLVRAVAALEPLRAVDALGRFDAYITVRGGGKSGQIDAIKLGIARALVQYNPDYRAKLKPLGFLTRDARVVERKKYGKHKARRAPQYSKR

Entity 10 Entity 10 polymer

Description description	30S RIBOSOMAL PROTEIN S10
Molecular weight formula_weight	11823.8 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	J

PKIRIKLRGFDHKTLDASAQKIVEAARRSGAQVSGPIPLPTRVRRFTVIRGPFKHKDSREHFELRTHNRLVDIINPNRKTIEQLMTLDLPTGVEIEIKTVGGGR

Entity 11 Entity 11 polymer

Description description	30S RIBOSOMAL PROTEIN S11
Molecular weight formula_weight	13606.7 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	K

AKKPSKKKVKRQVASGRAYIHASYNNTIVTITDPDGNPITWSSGGVIGYKGSRKGTPYAAQLAALDAAKKAMAYGMQSVDVIVRGTGAGREQAIRALQASGLQVKSIVDDTPVPHNGCRPKKKFRKAS

Entity 12 Entity 12 polymer

Description description	30S RIBOSOMAL PROTEIN S12
Molecular weight formula_weight	14506.2 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	L

PTINQLVRKGREKVRKKSKVPALKGAPFRRGVCTVVRTVTPKKPNSALRKVAKVRLTSGYEVTAYIPGEGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGVYDAAGVKDRKKSRSKYGTKKPKEAAKTAAKK

Entity 13 Entity 13 polymer

Description description	30S RIBOSOMAL PROTEIN S13
Molecular weight formula_weight	14207.7 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	M

ARIAGVEIPRNKRVDVALTYIYGIGKARAKEALEKTGINPATRVKDLTEAEVVRLREYVENTWKLEGELRAEVAANIKRLMDIGCYRGLRHRRGLPVRGQRTRTNARTRKGPRKTVAGKKKAPRK

Entity 14 Entity 14 polymer

Description description	30S RIBOSOMAL PROTEIN S14
Molecular weight formula_weight	7027.5 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	N

ARKALIEKAKRTPKFKVRAYTRCVRCGRARSVYRFFGLCRICLRELAHKGQLPGVRKASW

Entity 15 Entity 15 polymer

Description description	30S RIBOSOMAL PROTEIN S15
Molecular weight formula_weight	10447.2 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	O

PITKEEKQKVIQEFARFPGDTGSTEVQVALLTLRINRLSEHLKVHKKDHHSHRGLLMMVGQRRRLLRYLQREDPERYRALIEKLGIRG

Entity 16 Entity 16 polymer

Description description	30S RIBOSOMAL PROTEIN S16
Molecular weight formula_weight	10410.0 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	P

MVKIRLARFGSKHNPHYRIVVTDARRKRDGKYIEKIGYYDPRKTTPDWLKVDVERARYWLSVGAQPTDTARRLLRQAGVFRQEAREGA

Entity 17 Entity 17 polymer

Description description	30S RIBOSOMAL PROTEIN S17
Molecular weight formula_weight	12144.4 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	Q

PKKVLTGVVVSDKMQKTVTVLVERQFPHPLYGKVIKRSKKYLAHDPEERYKVGDVVEIIEARPISKRKRFRVLRLVEEGRLDLVEKYLVRRQNYASLSKRGGKA

Entity 18 Entity 18 polymer

Description description	30S RIBOSOMAL PROTEIN S18
Molecular weight formula_weight	10113.1 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	R

STKNAKPKKEAQRRPSRKAKVKATLGEFDLRDYRNVEVLKRFLSETGKILPRRRTGLSGKEQRILAKTIKRARILGLLPFTEKLVRK

Entity 19 Entity 19 polymer

Description description	30S RIBOSOMAL PROTEIN S19
Molecular weight formula_weight	10474.3 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	S

PRSLKKGVFVDDHLLEKVLELNAKGEKRLIKTWSRRSTIVPEMVGHTIAVYNGKQHVPVYITENMVGHKLGEFAPTRTYRGHGKEAKATKKK

Entity 20 Entity 20 polymer

Description description	30S RIBOSOMAL PROTEIN S20
Molecular weight formula_weight	11604.9 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	T

AQKKPKRNLSALKRHRQSLKRRLRNKAKKSAIKTLSKKAIQLAQEGKAEEALKIMRKAESLIDKAAKGSTLHKNAAARRKSRLMRKVRQLLEAAGAPLIGGGLSA

Entity 21 Entity 21 polymer

Description description	30S RIBOSOMAL PROTEIN THX
Molecular weight formula_weight	3218.8 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	U

GKGDRRTRRGKIWRGTYGKYRPRKKK

Entity 22 Entity 22 non-polymer

Description description	MAGNESIUM ION
Molecular weight formula_weight	24.3 kDa
Source method src_method	syn
Copy count entity_count	75

Entity 23 Entity 23 non-polymer

Description description	OCTADECATUNGSTENYL DIPHOSPHATE
Molecular weight formula_weight	4363.0 kDa
Source method src_method	syn
Copy count entity_count	14

Entity 24 Entity 24 non-polymer

Description description	TETRACYCLINE
Molecular weight formula_weight	444.4 kDa
Source method src_method	syn
Copy count entity_count	6

Entity 25 Entity 25 non-polymer

Description description	ZINC ION
Molecular weight formula_weight	65.4 kDa
Source method src_method	syn
Copy count entity_count	2

▼

6. Fold Classification (SCOP + CATH) 22 domains

SCOP 2.08 (22 domains)

Domain ID domain_id	d1i97b_
Class class	c — Alpha and beta proteins (a/b)
Fold Fold fold	c.23 — Flavodoxin-like
Superfamily Superfamily superfamily	c.23.15 — Ribosomal protein S2
Family Family family	c.23.15.1 — Ribosomal protein S2

Domain ID domain_id	d1i97c1
Class class	d — Alpha and beta proteins (a+b)
Fold Fold fold	d.52 — Alpha-lytic protease prodomain-like
Superfamily Superfamily superfamily	d.52.3 — Prokaryotic type KH domain (KH-domain type II)
Family Family family	d.52.3.1 — Prokaryotic type KH domain (KH-domain type II)

Domain ID domain_id	d1i97c2
Class class	d — Alpha and beta proteins (a+b)
Fold Fold fold	d.53 — Ribosomal protein S3 C-terminal domain
Superfamily Superfamily superfamily	d.53.1 — Ribosomal protein S3 C-terminal domain
Family Family family	d.53.1.1 — Ribosomal protein S3 C-terminal domain

Domain ID domain_id	d1i97d_
Class class	d — Alpha and beta proteins (a+b)
Fold Fold fold	d.66 — Alpha-L RNA-binding motif
Superfamily Superfamily superfamily	d.66.1 — Alpha-L RNA-binding motif
Family Family family	d.66.1.2 — Ribosomal protein S4 (bacteria)

Domain ID domain_id	d1i97e1
Class class	d — Alpha and beta proteins (a+b)
Fold Fold fold	d.14 — Ribosomal protein S5 domain 2-like
Superfamily Superfamily superfamily	d.14.1 — Ribosomal protein S5 domain 2-like
Family Family family	d.14.1.1 — Translational machinery components

Domain ID domain_id	d1i97e2
Class class	d — Alpha and beta proteins (a+b)
Fold Fold fold	d.50 — dsRBD-like
Superfamily Superfamily superfamily	d.50.1 — dsRNA-binding domain-like
Family Family family	d.50.1.2 — Ribosomal S5 protein, N-terminal domain

Domain ID domain_id	d1i97f_
Class class	d — Alpha and beta proteins (a+b)
Fold Fold fold	d.58 — Ferredoxin-like
Superfamily Superfamily superfamily	d.58.14 — Ribosomal protein S6
Family Family family	d.58.14.1 — Ribosomal protein S6

Domain ID domain_id	d1i97g_
Class class	a — All alpha proteins
Fold Fold fold	a.75 — Ribosomal protein S7
Superfamily Superfamily superfamily	a.75.1 — Ribosomal protein S7
Family Family family	a.75.1.1 — Ribosomal protein S7

Domain ID domain_id	d1i97h_
Class class	d — Alpha and beta proteins (a+b)
Fold Fold fold	d.140 — Ribosomal protein S8
Superfamily Superfamily superfamily	d.140.1 — Ribosomal protein S8
Family Family family	d.140.1.1 — Ribosomal protein S8

Domain ID domain_id	d1i97i_
Class class	d — Alpha and beta proteins (a+b)
Fold Fold fold	d.14 — Ribosomal protein S5 domain 2-like
Superfamily Superfamily superfamily	d.14.1 — Ribosomal protein S5 domain 2-like
Family Family family	d.14.1.1 — Translational machinery components

Domain ID domain_id	d1i97j_
Class class	d — Alpha and beta proteins (a+b)
Fold Fold fold	d.58 — Ferredoxin-like
Superfamily Superfamily superfamily	d.58.15 — Ribosomal protein S10
Family Family family	d.58.15.1 — Ribosomal protein S10

Domain ID domain_id	d1i97k_
Class class	c — Alpha and beta proteins (a/b)
Fold Fold fold	c.55 — Ribonuclease H-like motif
Superfamily Superfamily superfamily	c.55.4 — Translational machinery components
Family Family family	c.55.4.1 — Ribosomal protein L18 and S11

Domain ID domain_id	d1i97l_
Class class	b — All beta proteins
Fold Fold fold	b.40 — OB-fold
Superfamily Superfamily superfamily	b.40.4 — Nucleic acid-binding proteins
Family Family family	b.40.4.5 — Cold shock DNA-binding domain-like

Domain ID domain_id	d1i97m_
Class class	a — All alpha proteins
Fold Fold fold	a.156 — S13-like H2TH domain
Superfamily Superfamily superfamily	a.156.1 — S13-like H2TH domain
Family Family family	a.156.1.1 — Ribosomal protein S13

Domain ID domain_id	d1i97n_
Class class	g — Small proteins
Fold Fold fold	g.39 — Glucocorticoid receptor-like (DNA-binding domain)
Superfamily Superfamily superfamily	g.39.1 — Glucocorticoid receptor-like (DNA-binding domain)
Family Family family	g.39.1.7 — Ribosomal protein S14

Domain ID domain_id	d1i97o_
Class class	a — All alpha proteins
Fold Fold fold	a.16 — S15/NS1 RNA-binding domain
Superfamily Superfamily superfamily	a.16.1 — S15/NS1 RNA-binding domain
Family Family family	a.16.1.2 — Ribosomal protein S15

Domain ID domain_id	d1i97p_
Class class	d — Alpha and beta proteins (a+b)
Fold Fold fold	d.27 — Ribosomal protein S16
Superfamily Superfamily superfamily	d.27.1 — Ribosomal protein S16
Family Family family	d.27.1.1 — Ribosomal protein S16

Domain ID domain_id	d1i97q_
Class class	b — All beta proteins
Fold Fold fold	b.40 — OB-fold
Superfamily Superfamily superfamily	b.40.4 — Nucleic acid-binding proteins
Family Family family	b.40.4.5 — Cold shock DNA-binding domain-like

Domain ID domain_id	d1i97r_
Class class	a — All alpha proteins
Fold Fold fold	a.4 — DNA/RNA-binding 3-helical bundle
Superfamily Superfamily superfamily	a.4.8 — Ribosomal protein S18
Family Family family	a.4.8.1 — Ribosomal protein S18

Domain ID domain_id	d1i97s_
Class class	d — Alpha and beta proteins (a+b)
Fold Fold fold	d.28 — Ribosomal protein S19
Superfamily Superfamily superfamily	d.28.1 — Ribosomal protein S19
Family Family family	d.28.1.1 — Ribosomal protein S19

Domain ID domain_id	d1i97t_
Class class	a — All alpha proteins
Fold Fold fold	a.7 — Spectrin repeat-like
Superfamily Superfamily superfamily	a.7.6 — Ribosomal protein S20
Family Family family	a.7.6.1 — Ribosomal protein S20

Domain ID domain_id	d1i97u_
Class class	j — Peptides
Fold Fold fold	j.9 — Arg-rich RNA binding peptides
Superfamily Superfamily superfamily	j.9.1 — 30S ribosomal protein THX
Family Family family	j.9.1.1 — 30S ribosomal protein THX

▶

Unit-cell length a length_a	406.900 Å
Unit-cell length b length_b	406.900 Å
Unit-cell length c length_c	175.200 Å
Unit-cell angle α angle_alpha	90.00 °
Unit-cell angle β angle_beta	90.00 °
Unit-cell angle γ angle_gamma	90.00 °
Molecules per unit cell Z z_pdb	8

Space group space_group	P 41 21 2
Space-group number int_tables_number	92
Crystal system crystal_system	—

Resolution resolution	4.500 Å
Low-resolution limit resolution_low	35.000 Å
R factor r_factor	0.2260
R_work r_work	0.2230
R_free r_free	0.2540

CRYSTAL STRUCTURE OF THE 30S RIBOSOMAL SUBUNIT FROM THERMUS THERMOPHILUS IN COMPLEX WITH TETRACYCLINE

1. Protein Identity and Related Structures Protein Identity & Related Structures

30S RIBOSOMAL PROTEIN S4

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

30S RIBOSOMAL PROTEIN S5

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

30S RIBOSOMAL PROTEIN S6

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

30S RIBOSOMAL PROTEIN S7

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

30S RIBOSOMAL PROTEIN S8

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

30S RIBOSOMAL PROTEIN S10

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

30S RIBOSOMAL PROTEIN S12

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

30S RIBOSOMAL PROTEIN S14

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

30S RIBOSOMAL PROTEIN S15

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

30S RIBOSOMAL PROTEIN S17

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer