9e23

Cryo-EM structure of Pre-Chi dynein tail

Method: ELECTRON MICROSCOPY
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Dynein light chain roadblock-type 1

Homo sapiens

UniProt Q9NP97

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 16 Isoform 2C of Cytoplasmic dynein 1 intermediate chain 2 × 4 (Q13409) Dynein light chain 1, cytoplasmic × 2 (P63167) Dynein light chain Tctex-type 1 × 2 (P63172) Cytoplasmic dynein 1 light intermediate chain 2 × 2 (O43237) Cytoplasmic dynein 1 heavy chain 1 × 4 (Q14204) Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name DLRB1_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain E; PDBConstruct 1–96; UniProt 1–96 Author chain F; PDBConstruct 1–96; UniProt 1–96

Isoform 2C of Cytoplasmic dynein 1 intermediate chain 2

Homo sapiens

UniProt Q13409

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 16 Dynein light chain roadblock-type 1 × 2 (Q9NP97) Dynein light chain 1, cytoplasmic × 2 (P63167) Dynein light chain Tctex-type 1 × 2 (P63172) Cytoplasmic dynein 1 light intermediate chain 2 × 2 (O43237) Cytoplasmic dynein 1 heavy chain 1 × 4 (Q14204) Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name DC1I2_HUMAN
Isoform Q13409-3
PDB entities 2
Chains and sequence ranges Author chain D; PDBConstruct 1–612; UniProt 1–612 Author chain H; PDBConstruct 1–612; UniProt 1–612 Author chain g; PDBConstruct 1–612; UniProt 1–612 Author chain h; PDBConstruct 1–612; UniProt 1–612

Dynein light chain 1, cytoplasmic

Homo sapiens

UniProt P63167

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 16 Dynein light chain roadblock-type 1 × 2 (Q9NP97) Isoform 2C of Cytoplasmic dynein 1 intermediate chain 2 × 4 (Q13409) Dynein light chain Tctex-type 1 × 2 (P63172) Cytoplasmic dynein 1 light intermediate chain 2 × 2 (O43237) Cytoplasmic dynein 1 heavy chain 1 × 4 (Q14204) Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name DYL1_HUMAN
Isoform —
PDB entities 3
Chains and sequence ranges Author chain d; PDBConstruct 1–89; UniProt 1–89 Author chain i; PDBConstruct 1–89; UniProt 1–89

Dynein light chain Tctex-type 1

Homo sapiens

UniProt P63172

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 16 Dynein light chain roadblock-type 1 × 2 (Q9NP97) Isoform 2C of Cytoplasmic dynein 1 intermediate chain 2 × 4 (Q13409) Dynein light chain 1, cytoplasmic × 2 (P63167) Cytoplasmic dynein 1 light intermediate chain 2 × 2 (O43237) Cytoplasmic dynein 1 heavy chain 1 × 4 (Q14204) Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name DYLT1_HUMAN
Isoform —
PDB entities 4
Chains and sequence ranges Author chain k; PDBConstruct 1–113; UniProt 1–113 Author chain v; PDBConstruct 1–113; UniProt 1–113

Cytoplasmic dynein 1 light intermediate chain 2

Homo sapiens

UniProt O43237

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 16 Dynein light chain roadblock-type 1 × 2 (Q9NP97) Isoform 2C of Cytoplasmic dynein 1 intermediate chain 2 × 4 (Q13409) Dynein light chain 1, cytoplasmic × 2 (P63167) Dynein light chain Tctex-type 1 × 2 (P63172) Cytoplasmic dynein 1 heavy chain 1 × 4 (Q14204) Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name DC1L2_HUMAN
Isoform —
PDB entities 5
Chains and sequence ranges Author chain B; PDBConstruct 1–492; UniProt 1–492 Author chain C; PDBConstruct 1–492; UniProt 1–492

Cytoplasmic dynein 1 heavy chain 1

Homo sapiens

UniProt Q14204

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 16 Dynein light chain roadblock-type 1 × 2 (Q9NP97) Isoform 2C of Cytoplasmic dynein 1 intermediate chain 2 × 4 (Q13409) Dynein light chain 1, cytoplasmic × 2 (P63167) Dynein light chain Tctex-type 1 × 2 (P63172) Cytoplasmic dynein 1 light intermediate chain 2 × 2 (O43237) Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name DYHC1_HUMAN
Isoform —
PDB entities 6
Chains and sequence ranges Author chain A; PDBConstruct 199–4843; UniProt 2–4646 Author chain G; PDBConstruct 199–4843; UniProt 2–4646 Author chain e; PDBConstruct 199–4843; UniProt 2–4646 Author chain f; PDBConstruct 199–4843; UniProt 2–4646

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id9e23
Deposition date deposition_date2024-10-21
Structure title titleCryo-EM structure of Pre-Chi dynein tail
Keywords keywordsComplex, Human, MOTOR PROTEIN; MOTOR PROTEIN
Experimental Method methodELECTRON MICROSCOPY
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

9e23__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

9e23__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 109 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

9e23__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg(Guinier)93.09 Å
Rg (electron density)94.62 Å
Total Rg94.23 Å
Atom count21249
Residues4734
Excluded volume320680 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 9e23__assembly_1__model_1 16-meric (16) Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (6)

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7. Citations (1)