9ji8

Cryo-EM structure of alpha-synuclein-H21 fibril

Method: ELECTRON MICROSCOPY
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Alpha-synuclein

Homo sapiens

UniProt P37840

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 12 GLY-VAL-VAL-ALA-ALA-ALA-GLU-LYS-THR-LYS × 6 Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SYUA_HUMAN
Isoform —
PDB entities 2
Chains and sequence ranges Author chain F; PDBConstruct 1–63; UniProt 37–99 Author chain G; PDBConstruct 1–63; UniProt 37–99 Author chain K; PDBConstruct 1–63; UniProt 37–99 Author chain L; PDBConstruct 1–63; UniProt 37–99 Author chain M; PDBConstruct 1–63; UniProt 37–99 Author chain O; PDBConstruct 1–63; UniProt 37–99

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id9ji8
Deposition date deposition_date2024-09-11
Structure title titleCryo-EM structure of alpha-synuclein-H21 fibril
Keywords keywordsPROTEIN FIBRIL, Complex; PROTEIN FIBRIL
Experimental Method methodELECTRON MICROSCOPY
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

9ji8__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

9ji8__assembly_1__model_1 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

9ji8__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg(Guinier)30.37 Å
Rg (electron density)30.45 Å
Total Rg30.89 Å
Atom count3030
Residues438
Excluded volume54673 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 9ji8__assembly_1__model_1 12-meric (12) Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (2)

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7. Citations (1)