8ow1

Cryo-EM structure of the yeast Inner kinetochore bound to a CENP-A nucleosome.

Method: ELECTRON MICROSCOPY
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1. 蛋白身份与相关结构 Protein Identity & Related Structures

Centromere-binding protein 1

Saccharomyces cerevisiae

UniProt P17106

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白–DNA 异源复合物 蛋白 40 DNA 2 Inner kinetochore subunit CTF3 × 2 (Q12748) Inner kinetochore subunit MCM22 × 2 (P47167) Inner kinetochore subunit MCM16 × 2 (Q12262) Inner kinetochore subunit IML3 × 2 (P38265) Inner kinetochore subunit CHL4 × 2 (P38907) Centromere DNA-binding protein complex CBF3 subunit C × 1 (P35203) Centromere DNA-binding protein complex CBF3 subunit B × 2 (P40969) Suppressor of kinetochore protein 1 × 1 (P52286) Inner kinetochore subunit CTF19 × 2 (Q02732) Inner kinetochore subunit OKP1 × 2 (P53298) Inner kinetochore subunit MCM21 × 2 (Q06675) Inner kinetochore subunit CNN1 × 2 (P43618) Inner kinetochore subunit AME1 × 2 (P38313) Inner kinetochore subunit WIP1 × 2 (Q2V2P8) Inner kinetochore subunit NKP1 × 2 (Q12493) Inner kinetochore subunit NKP2 × 2 (Q06162) C0N3 × 1 C0N3 × 1 Histone H4 × 2 (P02309) Histone H2B.1 × 2 (P02293) Histone H3-like centromeric protein CSE4 × 2 (P36012) Histone H2A.1 × 2 (P04911) 与全部聚合物一致

数据库中的同蛋白其他状态

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UniProt名称 CBF1_YEAST
Isoform —
PDB实体 1
链与序列区间 作者链 A; PDB构建体 1–351; UniProt 1–351 作者链 B; PDB构建体 1–351; UniProt 1–351

Inner kinetochore subunit CTF3

Saccharomyces cerevisiae

UniProt Q12748

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白–DNA 异源复合物 蛋白 40 DNA 2 Centromere-binding protein 1 × 2 (P17106) Inner kinetochore subunit MCM22 × 2 (P47167) Inner kinetochore subunit MCM16 × 2 (Q12262) Inner kinetochore subunit IML3 × 2 (P38265) Inner kinetochore subunit CHL4 × 2 (P38907) Centromere DNA-binding protein complex CBF3 subunit C × 1 (P35203) Centromere DNA-binding protein complex CBF3 subunit B × 2 (P40969) Suppressor of kinetochore protein 1 × 1 (P52286) Inner kinetochore subunit CTF19 × 2 (Q02732) Inner kinetochore subunit OKP1 × 2 (P53298) Inner kinetochore subunit MCM21 × 2 (Q06675) Inner kinetochore subunit CNN1 × 2 (P43618) Inner kinetochore subunit AME1 × 2 (P38313) Inner kinetochore subunit WIP1 × 2 (Q2V2P8) Inner kinetochore subunit NKP1 × 2 (Q12493) Inner kinetochore subunit NKP2 × 2 (Q06162) C0N3 × 1 C0N3 × 1 Histone H4 × 2 (P02309) Histone H2B.1 × 2 (P02293) Histone H3-like centromeric protein CSE4 × 2 (P36012) Histone H2A.1 × 2 (P04911) 与全部聚合物一致

数据库中的同蛋白其他状态

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UniProt名称 CENPI_YEAST
Isoform —
PDB实体 2
链与序列区间 作者链 I; PDB构建体 1–733; UniProt 1–733 作者链 II; PDB构建体 1–733; UniProt 1–733

Inner kinetochore subunit MCM22

Saccharomyces cerevisiae

UniProt P47167

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白–DNA 异源复合物 蛋白 40 DNA 2 Centromere-binding protein 1 × 2 (P17106) Inner kinetochore subunit CTF3 × 2 (Q12748) Inner kinetochore subunit MCM16 × 2 (Q12262) Inner kinetochore subunit IML3 × 2 (P38265) Inner kinetochore subunit CHL4 × 2 (P38907) Centromere DNA-binding protein complex CBF3 subunit C × 1 (P35203) Centromere DNA-binding protein complex CBF3 subunit B × 2 (P40969) Suppressor of kinetochore protein 1 × 1 (P52286) Inner kinetochore subunit CTF19 × 2 (Q02732) Inner kinetochore subunit OKP1 × 2 (P53298) Inner kinetochore subunit MCM21 × 2 (Q06675) Inner kinetochore subunit CNN1 × 2 (P43618) Inner kinetochore subunit AME1 × 2 (P38313) Inner kinetochore subunit WIP1 × 2 (Q2V2P8) Inner kinetochore subunit NKP1 × 2 (Q12493) Inner kinetochore subunit NKP2 × 2 (Q06162) C0N3 × 1 C0N3 × 1 Histone H4 × 2 (P02309) Histone H2B.1 × 2 (P02293) Histone H3-like centromeric protein CSE4 × 2 (P36012) Histone H2A.1 × 2 (P04911) 与全部聚合物一致

数据库中的同蛋白其他状态

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UniProt名称 CENPK_YEAST
Isoform —
PDB实体 3
链与序列区间 作者链 K; PDB构建体 1–239; UniProt 1–239 作者链 KK; PDB构建体 1–239; UniProt 1–239

Inner kinetochore subunit MCM16

Saccharomyces cerevisiae

UniProt Q12262

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白–DNA 异源复合物 蛋白 40 DNA 2 Centromere-binding protein 1 × 2 (P17106) Inner kinetochore subunit CTF3 × 2 (Q12748) Inner kinetochore subunit MCM22 × 2 (P47167) Inner kinetochore subunit IML3 × 2 (P38265) Inner kinetochore subunit CHL4 × 2 (P38907) Centromere DNA-binding protein complex CBF3 subunit C × 1 (P35203) Centromere DNA-binding protein complex CBF3 subunit B × 2 (P40969) Suppressor of kinetochore protein 1 × 1 (P52286) Inner kinetochore subunit CTF19 × 2 (Q02732) Inner kinetochore subunit OKP1 × 2 (P53298) Inner kinetochore subunit MCM21 × 2 (Q06675) Inner kinetochore subunit CNN1 × 2 (P43618) Inner kinetochore subunit AME1 × 2 (P38313) Inner kinetochore subunit WIP1 × 2 (Q2V2P8) Inner kinetochore subunit NKP1 × 2 (Q12493) Inner kinetochore subunit NKP2 × 2 (Q06162) C0N3 × 1 C0N3 × 1 Histone H4 × 2 (P02309) Histone H2B.1 × 2 (P02293) Histone H3-like centromeric protein CSE4 × 2 (P36012) Histone H2A.1 × 2 (P04911) 与全部聚合物一致

数据库中的同蛋白其他状态

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UniProt名称 CENPH_YEAST
Isoform —
PDB实体 4
链与序列区间 作者链 H; PDB构建体 1–181; UniProt 1–181 作者链 HH; PDB构建体 1–181; UniProt 1–181

Inner kinetochore subunit IML3

Saccharomyces cerevisiae

UniProt P38265

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白–DNA 异源复合物 蛋白 40 DNA 2 Centromere-binding protein 1 × 2 (P17106) Inner kinetochore subunit CTF3 × 2 (Q12748) Inner kinetochore subunit MCM22 × 2 (P47167) Inner kinetochore subunit MCM16 × 2 (Q12262) Inner kinetochore subunit CHL4 × 2 (P38907) Centromere DNA-binding protein complex CBF3 subunit C × 1 (P35203) Centromere DNA-binding protein complex CBF3 subunit B × 2 (P40969) Suppressor of kinetochore protein 1 × 1 (P52286) Inner kinetochore subunit CTF19 × 2 (Q02732) Inner kinetochore subunit OKP1 × 2 (P53298) Inner kinetochore subunit MCM21 × 2 (Q06675) Inner kinetochore subunit CNN1 × 2 (P43618) Inner kinetochore subunit AME1 × 2 (P38313) Inner kinetochore subunit WIP1 × 2 (Q2V2P8) Inner kinetochore subunit NKP1 × 2 (Q12493) Inner kinetochore subunit NKP2 × 2 (Q06162) C0N3 × 1 C0N3 × 1 Histone H4 × 2 (P02309) Histone H2B.1 × 2 (P02293) Histone H3-like centromeric protein CSE4 × 2 (P36012) Histone H2A.1 × 2 (P04911) 与全部聚合物一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 CENPL_YEAST
Isoform —
PDB实体 5
链与序列区间 作者链 L; PDB构建体 1–245; UniProt 1–245 作者链 LL; PDB构建体 1–245; UniProt 1–245

Inner kinetochore subunit CHL4

Saccharomyces cerevisiae

UniProt P38907

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白–DNA 异源复合物 蛋白 40 DNA 2 Centromere-binding protein 1 × 2 (P17106) Inner kinetochore subunit CTF3 × 2 (Q12748) Inner kinetochore subunit MCM22 × 2 (P47167) Inner kinetochore subunit MCM16 × 2 (Q12262) Inner kinetochore subunit IML3 × 2 (P38265) Centromere DNA-binding protein complex CBF3 subunit C × 1 (P35203) Centromere DNA-binding protein complex CBF3 subunit B × 2 (P40969) Suppressor of kinetochore protein 1 × 1 (P52286) Inner kinetochore subunit CTF19 × 2 (Q02732) Inner kinetochore subunit OKP1 × 2 (P53298) Inner kinetochore subunit MCM21 × 2 (Q06675) Inner kinetochore subunit CNN1 × 2 (P43618) Inner kinetochore subunit AME1 × 2 (P38313) Inner kinetochore subunit WIP1 × 2 (Q2V2P8) Inner kinetochore subunit NKP1 × 2 (Q12493) Inner kinetochore subunit NKP2 × 2 (Q06162) C0N3 × 1 C0N3 × 1 Histone H4 × 2 (P02309) Histone H2B.1 × 2 (P02293) Histone H3-like centromeric protein CSE4 × 2 (P36012) Histone H2A.1 × 2 (P04911) 与全部聚合物一致

数据库中的同蛋白其他状态

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UniProt名称 CENPN_YEAST
Isoform —
PDB实体 6
链与序列区间 作者链 N; PDB构建体 1–458; UniProt 1–458 作者链 NN; PDB构建体 1–458; UniProt 1–458

Centromere DNA-binding protein complex CBF3 subunit C

Saccharomyces cerevisiae

UniProt P35203

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白–DNA 异源复合物 蛋白 40 DNA 2 Centromere-binding protein 1 × 2 (P17106) Inner kinetochore subunit CTF3 × 2 (Q12748) Inner kinetochore subunit MCM22 × 2 (P47167) Inner kinetochore subunit MCM16 × 2 (Q12262) Inner kinetochore subunit IML3 × 2 (P38265) Inner kinetochore subunit CHL4 × 2 (P38907) Centromere DNA-binding protein complex CBF3 subunit B × 2 (P40969) Suppressor of kinetochore protein 1 × 1 (P52286) Inner kinetochore subunit CTF19 × 2 (Q02732) Inner kinetochore subunit OKP1 × 2 (P53298) Inner kinetochore subunit MCM21 × 2 (Q06675) Inner kinetochore subunit CNN1 × 2 (P43618) Inner kinetochore subunit AME1 × 2 (P38313) Inner kinetochore subunit WIP1 × 2 (Q2V2P8) Inner kinetochore subunit NKP1 × 2 (Q12493) Inner kinetochore subunit NKP2 × 2 (Q06162) C0N3 × 1 C0N3 × 1 Histone H4 × 2 (P02309) Histone H2B.1 × 2 (P02293) Histone H3-like centromeric protein CSE4 × 2 (P36012) Histone H2A.1 × 2 (P04911) 与全部聚合物一致

数据库中的同蛋白其他状态

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UniProt名称 CBF3C_YEAST
Isoform —
PDB实体 7
链与序列区间 作者链 CT; PDB构建体 1–478; UniProt 1–478

Centromere DNA-binding protein complex CBF3 subunit B

Saccharomyces cerevisiae

UniProt P40969

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白–DNA 异源复合物 蛋白 40 DNA 2 Centromere-binding protein 1 × 2 (P17106) Inner kinetochore subunit CTF3 × 2 (Q12748) Inner kinetochore subunit MCM22 × 2 (P47167) Inner kinetochore subunit MCM16 × 2 (Q12262) Inner kinetochore subunit IML3 × 2 (P38265) Inner kinetochore subunit CHL4 × 2 (P38907) Centromere DNA-binding protein complex CBF3 subunit C × 1 (P35203) Suppressor of kinetochore protein 1 × 1 (P52286) Inner kinetochore subunit CTF19 × 2 (Q02732) Inner kinetochore subunit OKP1 × 2 (P53298) Inner kinetochore subunit MCM21 × 2 (Q06675) Inner kinetochore subunit CNN1 × 2 (P43618) Inner kinetochore subunit AME1 × 2 (P38313) Inner kinetochore subunit WIP1 × 2 (Q2V2P8) Inner kinetochore subunit NKP1 × 2 (Q12493) Inner kinetochore subunit NKP2 × 2 (Q06162) C0N3 × 1 C0N3 × 1 Histone H4 × 2 (P02309) Histone H2B.1 × 2 (P02293) Histone H3-like centromeric protein CSE4 × 2 (P36012) Histone H2A.1 × 2 (P04911) 与全部聚合物一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 CBF3B_YEAST
Isoform —
PDB实体 8
链与序列区间 作者链 CE; PDB构建体 1–608; UniProt 1–608 作者链 ce; PDB构建体 1–608; UniProt 1–608

Suppressor of kinetochore protein 1

Saccharomyces cerevisiae

UniProt P52286

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白–DNA 异源复合物 蛋白 40 DNA 2 Centromere-binding protein 1 × 2 (P17106) Inner kinetochore subunit CTF3 × 2 (Q12748) Inner kinetochore subunit MCM22 × 2 (P47167) Inner kinetochore subunit MCM16 × 2 (Q12262) Inner kinetochore subunit IML3 × 2 (P38265) Inner kinetochore subunit CHL4 × 2 (P38907) Centromere DNA-binding protein complex CBF3 subunit C × 1 (P35203) Centromere DNA-binding protein complex CBF3 subunit B × 2 (P40969) Inner kinetochore subunit CTF19 × 2 (Q02732) Inner kinetochore subunit OKP1 × 2 (P53298) Inner kinetochore subunit MCM21 × 2 (Q06675) Inner kinetochore subunit CNN1 × 2 (P43618) Inner kinetochore subunit AME1 × 2 (P38313) Inner kinetochore subunit WIP1 × 2 (Q2V2P8) Inner kinetochore subunit NKP1 × 2 (Q12493) Inner kinetochore subunit NKP2 × 2 (Q06162) C0N3 × 1 C0N3 × 1 Histone H4 × 2 (P02309) Histone H2B.1 × 2 (P02293) Histone H3-like centromeric protein CSE4 × 2 (P36012) Histone H2A.1 × 2 (P04911) 与全部聚合物一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 SKP1_YEAST
Isoform —
PDB实体 9
链与序列区间 作者链 SK; PDB构建体 1–194; UniProt 1–194

Inner kinetochore subunit CTF19

Saccharomyces cerevisiae

UniProt Q02732

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白–DNA 异源复合物 蛋白 40 DNA 2 Centromere-binding protein 1 × 2 (P17106) Inner kinetochore subunit CTF3 × 2 (Q12748) Inner kinetochore subunit MCM22 × 2 (P47167) Inner kinetochore subunit MCM16 × 2 (Q12262) Inner kinetochore subunit IML3 × 2 (P38265) Inner kinetochore subunit CHL4 × 2 (P38907) Centromere DNA-binding protein complex CBF3 subunit C × 1 (P35203) Centromere DNA-binding protein complex CBF3 subunit B × 2 (P40969) Suppressor of kinetochore protein 1 × 1 (P52286) Inner kinetochore subunit OKP1 × 2 (P53298) Inner kinetochore subunit MCM21 × 2 (Q06675) Inner kinetochore subunit CNN1 × 2 (P43618) Inner kinetochore subunit AME1 × 2 (P38313) Inner kinetochore subunit WIP1 × 2 (Q2V2P8) Inner kinetochore subunit NKP1 × 2 (Q12493) Inner kinetochore subunit NKP2 × 2 (Q06162) C0N3 × 1 C0N3 × 1 Histone H4 × 2 (P02309) Histone H2B.1 × 2 (P02293) Histone H3-like centromeric protein CSE4 × 2 (P36012) Histone H2A.1 × 2 (P04911) 与全部聚合物一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 CENPP_YEAST
Isoform —
PDB实体 10
链与序列区间 作者链 P; PDB构建体 1–369; UniProt 1–369 作者链 PP; PDB构建体 1–369; UniProt 1–369

Inner kinetochore subunit OKP1

Saccharomyces cerevisiae

UniProt P53298

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白–DNA 异源复合物 蛋白 40 DNA 2 Centromere-binding protein 1 × 2 (P17106) Inner kinetochore subunit CTF3 × 2 (Q12748) Inner kinetochore subunit MCM22 × 2 (P47167) Inner kinetochore subunit MCM16 × 2 (Q12262) Inner kinetochore subunit IML3 × 2 (P38265) Inner kinetochore subunit CHL4 × 2 (P38907) Centromere DNA-binding protein complex CBF3 subunit C × 1 (P35203) Centromere DNA-binding protein complex CBF3 subunit B × 2 (P40969) Suppressor of kinetochore protein 1 × 1 (P52286) Inner kinetochore subunit CTF19 × 2 (Q02732) Inner kinetochore subunit MCM21 × 2 (Q06675) Inner kinetochore subunit CNN1 × 2 (P43618) Inner kinetochore subunit AME1 × 2 (P38313) Inner kinetochore subunit WIP1 × 2 (Q2V2P8) Inner kinetochore subunit NKP1 × 2 (Q12493) Inner kinetochore subunit NKP2 × 2 (Q06162) C0N3 × 1 C0N3 × 1 Histone H4 × 2 (P02309) Histone H2B.1 × 2 (P02293) Histone H3-like centromeric protein CSE4 × 2 (P36012) Histone H2A.1 × 2 (P04911) 与全部聚合物一致

数据库中的同蛋白其他状态

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UniProt名称 CENPQ_YEAST
Isoform —
PDB实体 11
链与序列区间 作者链 Q; PDB构建体 1–406; UniProt 1–406 作者链 QQ; PDB构建体 1–406; UniProt 1–406

Inner kinetochore subunit MCM21

Saccharomyces cerevisiae

UniProt Q06675

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白–DNA 异源复合物 蛋白 40 DNA 2 Centromere-binding protein 1 × 2 (P17106) Inner kinetochore subunit CTF3 × 2 (Q12748) Inner kinetochore subunit MCM22 × 2 (P47167) Inner kinetochore subunit MCM16 × 2 (Q12262) Inner kinetochore subunit IML3 × 2 (P38265) Inner kinetochore subunit CHL4 × 2 (P38907) Centromere DNA-binding protein complex CBF3 subunit C × 1 (P35203) Centromere DNA-binding protein complex CBF3 subunit B × 2 (P40969) Suppressor of kinetochore protein 1 × 1 (P52286) Inner kinetochore subunit CTF19 × 2 (Q02732) Inner kinetochore subunit OKP1 × 2 (P53298) Inner kinetochore subunit CNN1 × 2 (P43618) Inner kinetochore subunit AME1 × 2 (P38313) Inner kinetochore subunit WIP1 × 2 (Q2V2P8) Inner kinetochore subunit NKP1 × 2 (Q12493) Inner kinetochore subunit NKP2 × 2 (Q06162) C0N3 × 1 C0N3 × 1 Histone H4 × 2 (P02309) Histone H2B.1 × 2 (P02293) Histone H3-like centromeric protein CSE4 × 2 (P36012) Histone H2A.1 × 2 (P04911) 与全部聚合物一致

数据库中的同蛋白其他状态

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UniProt名称 CENPO_YEAST
Isoform —
PDB实体 12
链与序列区间 作者链 O; PDB构建体 1–368; UniProt 1–368 作者链 OO; PDB构建体 1–368; UniProt 1–368

Inner kinetochore subunit CNN1

Saccharomyces cerevisiae

UniProt P43618

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白–DNA 异源复合物 蛋白 40 DNA 2 Centromere-binding protein 1 × 2 (P17106) Inner kinetochore subunit CTF3 × 2 (Q12748) Inner kinetochore subunit MCM22 × 2 (P47167) Inner kinetochore subunit MCM16 × 2 (Q12262) Inner kinetochore subunit IML3 × 2 (P38265) Inner kinetochore subunit CHL4 × 2 (P38907) Centromere DNA-binding protein complex CBF3 subunit C × 1 (P35203) Centromere DNA-binding protein complex CBF3 subunit B × 2 (P40969) Suppressor of kinetochore protein 1 × 1 (P52286) Inner kinetochore subunit CTF19 × 2 (Q02732) Inner kinetochore subunit OKP1 × 2 (P53298) Inner kinetochore subunit MCM21 × 2 (Q06675) Inner kinetochore subunit AME1 × 2 (P38313) Inner kinetochore subunit WIP1 × 2 (Q2V2P8) Inner kinetochore subunit NKP1 × 2 (Q12493) Inner kinetochore subunit NKP2 × 2 (Q06162) C0N3 × 1 C0N3 × 1 Histone H4 × 2 (P02309) Histone H2B.1 × 2 (P02293) Histone H3-like centromeric protein CSE4 × 2 (P36012) Histone H2A.1 × 2 (P04911) 与全部聚合物一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 CENPT_YEAST
Isoform —
PDB实体 13
链与序列区间 作者链 T; PDB构建体 1–361; UniProt 1–361 作者链 TT; PDB构建体 1–361; UniProt 1–361

Inner kinetochore subunit AME1

Saccharomyces cerevisiae

UniProt P38313

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白–DNA 异源复合物 蛋白 40 DNA 2 Centromere-binding protein 1 × 2 (P17106) Inner kinetochore subunit CTF3 × 2 (Q12748) Inner kinetochore subunit MCM22 × 2 (P47167) Inner kinetochore subunit MCM16 × 2 (Q12262) Inner kinetochore subunit IML3 × 2 (P38265) Inner kinetochore subunit CHL4 × 2 (P38907) Centromere DNA-binding protein complex CBF3 subunit C × 1 (P35203) Centromere DNA-binding protein complex CBF3 subunit B × 2 (P40969) Suppressor of kinetochore protein 1 × 1 (P52286) Inner kinetochore subunit CTF19 × 2 (Q02732) Inner kinetochore subunit OKP1 × 2 (P53298) Inner kinetochore subunit MCM21 × 2 (Q06675) Inner kinetochore subunit CNN1 × 2 (P43618) Inner kinetochore subunit WIP1 × 2 (Q2V2P8) Inner kinetochore subunit NKP1 × 2 (Q12493) Inner kinetochore subunit NKP2 × 2 (Q06162) C0N3 × 1 C0N3 × 1 Histone H4 × 2 (P02309) Histone H2B.1 × 2 (P02293) Histone H3-like centromeric protein CSE4 × 2 (P36012) Histone H2A.1 × 2 (P04911) 与全部聚合物一致

数据库中的同蛋白其他状态

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UniProt名称 CENPU_YEAST
Isoform —
PDB实体 14
链与序列区间 作者链 U; PDB构建体 1–324; UniProt 1–324 作者链 UU; PDB构建体 1–324; UniProt 1–324

Inner kinetochore subunit WIP1

Saccharomyces cerevisiae

UniProt Q2V2P8

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白–DNA 异源复合物 蛋白 40 DNA 2 Centromere-binding protein 1 × 2 (P17106) Inner kinetochore subunit CTF3 × 2 (Q12748) Inner kinetochore subunit MCM22 × 2 (P47167) Inner kinetochore subunit MCM16 × 2 (Q12262) Inner kinetochore subunit IML3 × 2 (P38265) Inner kinetochore subunit CHL4 × 2 (P38907) Centromere DNA-binding protein complex CBF3 subunit C × 1 (P35203) Centromere DNA-binding protein complex CBF3 subunit B × 2 (P40969) Suppressor of kinetochore protein 1 × 1 (P52286) Inner kinetochore subunit CTF19 × 2 (Q02732) Inner kinetochore subunit OKP1 × 2 (P53298) Inner kinetochore subunit MCM21 × 2 (Q06675) Inner kinetochore subunit CNN1 × 2 (P43618) Inner kinetochore subunit AME1 × 2 (P38313) Inner kinetochore subunit NKP1 × 2 (Q12493) Inner kinetochore subunit NKP2 × 2 (Q06162) C0N3 × 1 C0N3 × 1 Histone H4 × 2 (P02309) Histone H2B.1 × 2 (P02293) Histone H3-like centromeric protein CSE4 × 2 (P36012) Histone H2A.1 × 2 (P04911) 与全部聚合物一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 CENPW_YEAST
Isoform —
PDB实体 15
链与序列区间 作者链 W; PDB构建体 1–89; UniProt 1–89 作者链 WW; PDB构建体 1–89; UniProt 1–89

Inner kinetochore subunit NKP1

Saccharomyces cerevisiae

UniProt Q12493

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白–DNA 异源复合物 蛋白 40 DNA 2 Centromere-binding protein 1 × 2 (P17106) Inner kinetochore subunit CTF3 × 2 (Q12748) Inner kinetochore subunit MCM22 × 2 (P47167) Inner kinetochore subunit MCM16 × 2 (Q12262) Inner kinetochore subunit IML3 × 2 (P38265) Inner kinetochore subunit CHL4 × 2 (P38907) Centromere DNA-binding protein complex CBF3 subunit C × 1 (P35203) Centromere DNA-binding protein complex CBF3 subunit B × 2 (P40969) Suppressor of kinetochore protein 1 × 1 (P52286) Inner kinetochore subunit CTF19 × 2 (Q02732) Inner kinetochore subunit OKP1 × 2 (P53298) Inner kinetochore subunit MCM21 × 2 (Q06675) Inner kinetochore subunit CNN1 × 2 (P43618) Inner kinetochore subunit AME1 × 2 (P38313) Inner kinetochore subunit WIP1 × 2 (Q2V2P8) Inner kinetochore subunit NKP2 × 2 (Q06162) C0N3 × 1 C0N3 × 1 Histone H4 × 2 (P02309) Histone H2B.1 × 2 (P02293) Histone H3-like centromeric protein CSE4 × 2 (P36012) Histone H2A.1 × 2 (P04911) 与全部聚合物一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 NKP1_YEAST
Isoform —
PDB实体 16
链与序列区间 作者链 Y; PDB构建体 1–238; UniProt 1–238 作者链 YY; PDB构建体 1–238; UniProt 1–238

Inner kinetochore subunit NKP2

Saccharomyces cerevisiae

UniProt Q06162

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白–DNA 异源复合物 蛋白 40 DNA 2 Centromere-binding protein 1 × 2 (P17106) Inner kinetochore subunit CTF3 × 2 (Q12748) Inner kinetochore subunit MCM22 × 2 (P47167) Inner kinetochore subunit MCM16 × 2 (Q12262) Inner kinetochore subunit IML3 × 2 (P38265) Inner kinetochore subunit CHL4 × 2 (P38907) Centromere DNA-binding protein complex CBF3 subunit C × 1 (P35203) Centromere DNA-binding protein complex CBF3 subunit B × 2 (P40969) Suppressor of kinetochore protein 1 × 1 (P52286) Inner kinetochore subunit CTF19 × 2 (Q02732) Inner kinetochore subunit OKP1 × 2 (P53298) Inner kinetochore subunit MCM21 × 2 (Q06675) Inner kinetochore subunit CNN1 × 2 (P43618) Inner kinetochore subunit AME1 × 2 (P38313) Inner kinetochore subunit WIP1 × 2 (Q2V2P8) Inner kinetochore subunit NKP1 × 2 (Q12493) C0N3 × 1 C0N3 × 1 Histone H4 × 2 (P02309) Histone H2B.1 × 2 (P02293) Histone H3-like centromeric protein CSE4 × 2 (P36012) Histone H2A.1 × 2 (P04911) 与全部聚合物一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 NKP2_YEAST
Isoform —
PDB实体 17
链与序列区间 作者链 Z; PDB构建体 1–153; UniProt 1–153 作者链 ZZ; PDB构建体 1–153; UniProt 1–153

Histone H4

Saccharomyces cerevisiae

UniProt P02309

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白–DNA 异源复合物 蛋白 40 DNA 2 Centromere-binding protein 1 × 2 (P17106) Inner kinetochore subunit CTF3 × 2 (Q12748) Inner kinetochore subunit MCM22 × 2 (P47167) Inner kinetochore subunit MCM16 × 2 (Q12262) Inner kinetochore subunit IML3 × 2 (P38265) Inner kinetochore subunit CHL4 × 2 (P38907) Centromere DNA-binding protein complex CBF3 subunit C × 1 (P35203) Centromere DNA-binding protein complex CBF3 subunit B × 2 (P40969) Suppressor of kinetochore protein 1 × 1 (P52286) Inner kinetochore subunit CTF19 × 2 (Q02732) Inner kinetochore subunit OKP1 × 2 (P53298) Inner kinetochore subunit MCM21 × 2 (Q06675) Inner kinetochore subunit CNN1 × 2 (P43618) Inner kinetochore subunit AME1 × 2 (P38313) Inner kinetochore subunit WIP1 × 2 (Q2V2P8) Inner kinetochore subunit NKP1 × 2 (Q12493) Inner kinetochore subunit NKP2 × 2 (Q06162) C0N3 × 1 C0N3 × 1 Histone H2B.1 × 2 (P02293) Histone H3-like centromeric protein CSE4 × 2 (P36012) Histone H2A.1 × 2 (P04911) 与全部聚合物一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 H4_YEAST
Isoform —
PDB实体 20
链与序列区间 作者链 b; PDB构建体 1–103; UniProt 1–103 作者链 f; PDB构建体 1–103; UniProt 1–103

Histone H2B.1

Saccharomyces cerevisiae

UniProt P02293

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白–DNA 异源复合物 蛋白 40 DNA 2 Centromere-binding protein 1 × 2 (P17106) Inner kinetochore subunit CTF3 × 2 (Q12748) Inner kinetochore subunit MCM22 × 2 (P47167) Inner kinetochore subunit MCM16 × 2 (Q12262) Inner kinetochore subunit IML3 × 2 (P38265) Inner kinetochore subunit CHL4 × 2 (P38907) Centromere DNA-binding protein complex CBF3 subunit C × 1 (P35203) Centromere DNA-binding protein complex CBF3 subunit B × 2 (P40969) Suppressor of kinetochore protein 1 × 1 (P52286) Inner kinetochore subunit CTF19 × 2 (Q02732) Inner kinetochore subunit OKP1 × 2 (P53298) Inner kinetochore subunit MCM21 × 2 (Q06675) Inner kinetochore subunit CNN1 × 2 (P43618) Inner kinetochore subunit AME1 × 2 (P38313) Inner kinetochore subunit WIP1 × 2 (Q2V2P8) Inner kinetochore subunit NKP1 × 2 (Q12493) Inner kinetochore subunit NKP2 × 2 (Q06162) C0N3 × 1 C0N3 × 1 Histone H4 × 2 (P02309) Histone H3-like centromeric protein CSE4 × 2 (P36012) Histone H2A.1 × 2 (P04911) 与全部聚合物一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 H2B1_YEAST
Isoform —
PDB实体 21
链与序列区间 作者链 d; PDB构建体 1–131; UniProt 1–131 作者链 h; PDB构建体 1–131; UniProt 1–131

Histone H3-like centromeric protein CSE4

Saccharomyces cerevisiae

UniProt P36012

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白–DNA 异源复合物 蛋白 40 DNA 2 Centromere-binding protein 1 × 2 (P17106) Inner kinetochore subunit CTF3 × 2 (Q12748) Inner kinetochore subunit MCM22 × 2 (P47167) Inner kinetochore subunit MCM16 × 2 (Q12262) Inner kinetochore subunit IML3 × 2 (P38265) Inner kinetochore subunit CHL4 × 2 (P38907) Centromere DNA-binding protein complex CBF3 subunit C × 1 (P35203) Centromere DNA-binding protein complex CBF3 subunit B × 2 (P40969) Suppressor of kinetochore protein 1 × 1 (P52286) Inner kinetochore subunit CTF19 × 2 (Q02732) Inner kinetochore subunit OKP1 × 2 (P53298) Inner kinetochore subunit MCM21 × 2 (Q06675) Inner kinetochore subunit CNN1 × 2 (P43618) Inner kinetochore subunit AME1 × 2 (P38313) Inner kinetochore subunit WIP1 × 2 (Q2V2P8) Inner kinetochore subunit NKP1 × 2 (Q12493) Inner kinetochore subunit NKP2 × 2 (Q06162) C0N3 × 1 C0N3 × 1 Histone H4 × 2 (P02309) Histone H2B.1 × 2 (P02293) Histone H2A.1 × 2 (P04911) 与全部聚合物一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 CENPA_YEAST
Isoform —
PDB实体 22
链与序列区间 作者链 a; PDB构建体 1–229; UniProt 1–229 作者链 e; PDB构建体 1–229; UniProt 1–229

Histone H2A.1

Saccharomyces cerevisiae

UniProt P04911

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白–DNA 异源复合物 蛋白 40 DNA 2 Centromere-binding protein 1 × 2 (P17106) Inner kinetochore subunit CTF3 × 2 (Q12748) Inner kinetochore subunit MCM22 × 2 (P47167) Inner kinetochore subunit MCM16 × 2 (Q12262) Inner kinetochore subunit IML3 × 2 (P38265) Inner kinetochore subunit CHL4 × 2 (P38907) Centromere DNA-binding protein complex CBF3 subunit C × 1 (P35203) Centromere DNA-binding protein complex CBF3 subunit B × 2 (P40969) Suppressor of kinetochore protein 1 × 1 (P52286) Inner kinetochore subunit CTF19 × 2 (Q02732) Inner kinetochore subunit OKP1 × 2 (P53298) Inner kinetochore subunit MCM21 × 2 (Q06675) Inner kinetochore subunit CNN1 × 2 (P43618) Inner kinetochore subunit AME1 × 2 (P38313) Inner kinetochore subunit WIP1 × 2 (Q2V2P8) Inner kinetochore subunit NKP1 × 2 (Q12493) Inner kinetochore subunit NKP2 × 2 (Q06162) C0N3 × 1 C0N3 × 1 Histone H4 × 2 (P02309) Histone H2B.1 × 2 (P02293) Histone H3-like centromeric protein CSE4 × 2 (P36012) 与全部聚合物一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 H2A1_YEAST
Isoform —
PDB实体 23
链与序列区间 作者链 c; PDB构建体 1–132; UniProt 1–132 作者链 g; PDB构建体 1–132; UniProt 1–132

页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中;数据库内部编号、导入时间和 assembly 操作表达式仅用于维护,因此不在读者页面展示。

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2. 结构基本信息 2. Structure Basics

条目编号 entry_id8ow1
沉积日期 deposition_date2023-04-26
结构标题 titleCryo-EM structure of the yeast Inner kinetochore bound to a CENP-A nucleosome.
关键词 keywordskinetochore, point centromere, CENP-A nucleosome, topological entrapment, centromeric DNA, CELL CYCLE; CELL CYCLE
实验方法 methodELECTRON MICROSCOPY
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3. Official assembly/model 理论 SAXS Official SAXS Profiles

页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。

8ow1__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

下载该曲线 .dat

8ow1__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 109 1010 q (1/Angstrom) I(q)
100 个绘图点;横轴和纵轴均采用对数尺度。

8ow1__assembly_1__model_1 | P(r) · Pending

新版 assembly/model P(r) 尚未计算 此处仅保留位置,不展示旧数据 r (Angstrom) P(r)
P(r) 将按相同 assembly/model 分别计算和展示。
Rg(Guinier)85.69 Å
Rg(电子密度)85.80 Å
总 Rg85.69 Å
原子数78671
残基数9238
排除体积1391500 ų
最大 q0.500 Å⁻¹
Assembly Model 结构单元 聚集说明 状态 CRYSOL 操作
1 1 8ow1__assembly_1__model_1 42-meric (42) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
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4. 晶体学与实验 4. Crystallography & Experiment

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5. 实体与聚合物信息 Entities & Polymers (23)

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7. 引用文献 (1)