9gj6

Human 80S ribosome in complex with NatA in proximal and distal position

Method: ELECTRON MICROSCOPY

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1. Protein Identity and Related Structures Protein Identity & Related Structures

N-alpha-acetyltransferase 10

Homo sapiens

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 15 RNA 2	N-alpha-acetyltransferase 15, NatA auxiliary subunit × 2 （Q9BXJ9） 28S rRNA × 1 5.8S rRNA × 1 60S ribosomal protein L4 × 1 （P36578） Large ribosomal subunit protein eL6 × 1 （Q02878） 60S ribosomal protein L38 × 1 （P63173） Large ribosomal subunit protein uL24 × 1 （P61254） 60S ribosomal protein L35 × 1 （P42766） 60S ribosomal protein L23a × 1 （P62750） 60S ribosomal protein L19 × 1 （P84098） 60S ribosomal protein L28 × 1 （P46779） Large ribosomal subunit protein eL22 × 1 （P35268） 60S ribosomal protein L31 × 1 （P62899） 60S ribosomal protein L17 × 1 （P18621） INOSITOL HEXAKISPHOSPHATE × 2	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	NAA10_HUMAN
Isoform	—
PDB entities	1
Chains and sequence ranges	Author chain A； PDBConstruct 1–235； UniProt 1–235 Author chain C； PDBConstruct 1–235； UniProt 1–235

N-alpha-acetyltransferase 15, NatA auxiliary subunit

Homo sapiens

UniProt Q9BXJ9

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 15 RNA 2	N-alpha-acetyltransferase 10 × 2 （P41227） 28S rRNA × 1 5.8S rRNA × 1 60S ribosomal protein L4 × 1 （P36578） Large ribosomal subunit protein eL6 × 1 （Q02878） 60S ribosomal protein L38 × 1 （P63173） Large ribosomal subunit protein uL24 × 1 （P61254） 60S ribosomal protein L35 × 1 （P42766） 60S ribosomal protein L23a × 1 （P62750） 60S ribosomal protein L19 × 1 （P84098） 60S ribosomal protein L28 × 1 （P46779） Large ribosomal subunit protein eL22 × 1 （P35268） 60S ribosomal protein L31 × 1 （P62899） 60S ribosomal protein L17 × 1 （P18621） INOSITOL HEXAKISPHOSPHATE × 2	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	NAA15_HUMAN
Isoform	—
PDB entities	2
Chains and sequence ranges	Author chain B； PDBConstruct 1–840； UniProt 1–841 Author chain D； PDBConstruct 1–840； UniProt 1–841

60S ribosomal protein L4

Homo sapiens

UniProt P36578

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 15 RNA 2	N-alpha-acetyltransferase 10 × 2 （P41227） N-alpha-acetyltransferase 15, NatA auxiliary subunit × 2 （Q9BXJ9） 28S rRNA × 1 5.8S rRNA × 1 Large ribosomal subunit protein eL6 × 1 （Q02878） 60S ribosomal protein L38 × 1 （P63173） Large ribosomal subunit protein uL24 × 1 （P61254） 60S ribosomal protein L35 × 1 （P42766） 60S ribosomal protein L23a × 1 （P62750） 60S ribosomal protein L19 × 1 （P84098） 60S ribosomal protein L28 × 1 （P46779） Large ribosomal subunit protein eL22 × 1 （P35268） 60S ribosomal protein L31 × 1 （P62899） 60S ribosomal protein L17 × 1 （P18621） INOSITOL HEXAKISPHOSPHATE × 2	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL4_HUMAN
Isoform	—
PDB entities	5
Chains and sequence ranges	Author chain LC； PDBConstruct 1–427； UniProt 1–427

Large ribosomal subunit protein eL6

Homo sapiens

UniProt Q02878

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 15 RNA 2	N-alpha-acetyltransferase 10 × 2 （P41227） N-alpha-acetyltransferase 15, NatA auxiliary subunit × 2 （Q9BXJ9） 28S rRNA × 1 5.8S rRNA × 1 60S ribosomal protein L4 × 1 （P36578） 60S ribosomal protein L38 × 1 （P63173） Large ribosomal subunit protein uL24 × 1 （P61254） 60S ribosomal protein L35 × 1 （P42766） 60S ribosomal protein L23a × 1 （P62750） 60S ribosomal protein L19 × 1 （P84098） 60S ribosomal protein L28 × 1 （P46779） Large ribosomal subunit protein eL22 × 1 （P35268） 60S ribosomal protein L31 × 1 （P62899） 60S ribosomal protein L17 × 1 （P18621） INOSITOL HEXAKISPHOSPHATE × 2	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL6_HUMAN
Isoform	—
PDB entities	6
Chains and sequence ranges	Author chain LE； PDBConstruct 1–288； UniProt 1–288

60S ribosomal protein L38

Homo sapiens

UniProt P63173

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 15 RNA 2	N-alpha-acetyltransferase 10 × 2 （P41227） N-alpha-acetyltransferase 15, NatA auxiliary subunit × 2 （Q9BXJ9） 28S rRNA × 1 5.8S rRNA × 1 60S ribosomal protein L4 × 1 （P36578） Large ribosomal subunit protein eL6 × 1 （Q02878） Large ribosomal subunit protein uL24 × 1 （P61254） 60S ribosomal protein L35 × 1 （P42766） 60S ribosomal protein L23a × 1 （P62750） 60S ribosomal protein L19 × 1 （P84098） 60S ribosomal protein L28 × 1 （P46779） Large ribosomal subunit protein eL22 × 1 （P35268） 60S ribosomal protein L31 × 1 （P62899） 60S ribosomal protein L17 × 1 （P18621） INOSITOL HEXAKISPHOSPHATE × 2	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL38_HUMAN
Isoform	—
PDB entities	7
Chains and sequence ranges	Author chain Lk； PDBConstruct 1–70； UniProt 1–70

Large ribosomal subunit protein uL24

Homo sapiens

UniProt P61254

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 15 RNA 2	N-alpha-acetyltransferase 10 × 2 （P41227） N-alpha-acetyltransferase 15, NatA auxiliary subunit × 2 （Q9BXJ9） 28S rRNA × 1 5.8S rRNA × 1 60S ribosomal protein L4 × 1 （P36578） Large ribosomal subunit protein eL6 × 1 （Q02878） 60S ribosomal protein L38 × 1 （P63173） 60S ribosomal protein L35 × 1 （P42766） 60S ribosomal protein L23a × 1 （P62750） 60S ribosomal protein L19 × 1 （P84098） 60S ribosomal protein L28 × 1 （P46779） Large ribosomal subunit protein eL22 × 1 （P35268） 60S ribosomal protein L31 × 1 （P62899） 60S ribosomal protein L17 × 1 （P18621） INOSITOL HEXAKISPHOSPHATE × 2	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL26_HUMAN
Isoform	—
PDB entities	8
Chains and sequence ranges	Author chain LY； PDBConstruct 1–145； UniProt 1–145

60S ribosomal protein L35

Homo sapiens

UniProt P42766

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 15 RNA 2	N-alpha-acetyltransferase 10 × 2 （P41227） N-alpha-acetyltransferase 15, NatA auxiliary subunit × 2 （Q9BXJ9） 28S rRNA × 1 5.8S rRNA × 1 60S ribosomal protein L4 × 1 （P36578） Large ribosomal subunit protein eL6 × 1 （Q02878） 60S ribosomal protein L38 × 1 （P63173） Large ribosomal subunit protein uL24 × 1 （P61254） 60S ribosomal protein L23a × 1 （P62750） 60S ribosomal protein L19 × 1 （P84098） 60S ribosomal protein L28 × 1 （P46779） Large ribosomal subunit protein eL22 × 1 （P35268） 60S ribosomal protein L31 × 1 （P62899） 60S ribosomal protein L17 × 1 （P18621） INOSITOL HEXAKISPHOSPHATE × 2	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL35_HUMAN
Isoform	—
PDB entities	9
Chains and sequence ranges	Author chain Lh； PDBConstruct 1–122； UniProt 2–123

60S ribosomal protein L23a

Homo sapiens

UniProt P62750

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 15 RNA 2	N-alpha-acetyltransferase 10 × 2 （P41227） N-alpha-acetyltransferase 15, NatA auxiliary subunit × 2 （Q9BXJ9） 28S rRNA × 1 5.8S rRNA × 1 60S ribosomal protein L4 × 1 （P36578） Large ribosomal subunit protein eL6 × 1 （Q02878） 60S ribosomal protein L38 × 1 （P63173） Large ribosomal subunit protein uL24 × 1 （P61254） 60S ribosomal protein L35 × 1 （P42766） 60S ribosomal protein L19 × 1 （P84098） 60S ribosomal protein L28 × 1 （P46779） Large ribosomal subunit protein eL22 × 1 （P35268） 60S ribosomal protein L31 × 1 （P62899） 60S ribosomal protein L17 × 1 （P18621） INOSITOL HEXAKISPHOSPHATE × 2	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL23A_HUMAN
Isoform	—
PDB entities	10
Chains and sequence ranges	Author chain LX； PDBConstruct 1–156； UniProt 1–156

60S ribosomal protein L19

Homo sapiens

UniProt P84098

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 15 RNA 2	N-alpha-acetyltransferase 10 × 2 （P41227） N-alpha-acetyltransferase 15, NatA auxiliary subunit × 2 （Q9BXJ9） 28S rRNA × 1 5.8S rRNA × 1 60S ribosomal protein L4 × 1 （P36578） Large ribosomal subunit protein eL6 × 1 （Q02878） 60S ribosomal protein L38 × 1 （P63173） Large ribosomal subunit protein uL24 × 1 （P61254） 60S ribosomal protein L35 × 1 （P42766） 60S ribosomal protein L23a × 1 （P62750） 60S ribosomal protein L28 × 1 （P46779） Large ribosomal subunit protein eL22 × 1 （P35268） 60S ribosomal protein L31 × 1 （P62899） 60S ribosomal protein L17 × 1 （P18621） INOSITOL HEXAKISPHOSPHATE × 2	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL19_HUMAN
Isoform	—
PDB entities	11
Chains and sequence ranges	Author chain LR； PDBConstruct 1–196； UniProt 1–196

60S ribosomal protein L28

Homo sapiens

UniProt P46779

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 15 RNA 2	N-alpha-acetyltransferase 10 × 2 （P41227） N-alpha-acetyltransferase 15, NatA auxiliary subunit × 2 （Q9BXJ9） 28S rRNA × 1 5.8S rRNA × 1 60S ribosomal protein L4 × 1 （P36578） Large ribosomal subunit protein eL6 × 1 （Q02878） 60S ribosomal protein L38 × 1 （P63173） Large ribosomal subunit protein uL24 × 1 （P61254） 60S ribosomal protein L35 × 1 （P42766） 60S ribosomal protein L23a × 1 （P62750） 60S ribosomal protein L19 × 1 （P84098） Large ribosomal subunit protein eL22 × 1 （P35268） 60S ribosomal protein L31 × 1 （P62899） 60S ribosomal protein L17 × 1 （P18621） INOSITOL HEXAKISPHOSPHATE × 2	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL28_HUMAN
Isoform	—
PDB entities	12
Chains and sequence ranges	Author chain Lr； PDBConstruct 1–137； UniProt 1–137

Large ribosomal subunit protein eL22

Homo sapiens

UniProt P35268

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 15 RNA 2	N-alpha-acetyltransferase 10 × 2 （P41227） N-alpha-acetyltransferase 15, NatA auxiliary subunit × 2 （Q9BXJ9） 28S rRNA × 1 5.8S rRNA × 1 60S ribosomal protein L4 × 1 （P36578） Large ribosomal subunit protein eL6 × 1 （Q02878） 60S ribosomal protein L38 × 1 （P63173） Large ribosomal subunit protein uL24 × 1 （P61254） 60S ribosomal protein L35 × 1 （P42766） 60S ribosomal protein L23a × 1 （P62750） 60S ribosomal protein L19 × 1 （P84098） 60S ribosomal protein L28 × 1 （P46779） 60S ribosomal protein L31 × 1 （P62899） 60S ribosomal protein L17 × 1 （P18621） INOSITOL HEXAKISPHOSPHATE × 2	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL22_HUMAN
Isoform	—
PDB entities	13
Chains and sequence ranges	Author chain LU； PDBConstruct 1–127； UniProt 2–128

60S ribosomal protein L31

Homo sapiens

UniProt P62899

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 15 RNA 2	N-alpha-acetyltransferase 10 × 2 （P41227） N-alpha-acetyltransferase 15, NatA auxiliary subunit × 2 （Q9BXJ9） 28S rRNA × 1 5.8S rRNA × 1 60S ribosomal protein L4 × 1 （P36578） Large ribosomal subunit protein eL6 × 1 （Q02878） 60S ribosomal protein L38 × 1 （P63173） Large ribosomal subunit protein uL24 × 1 （P61254） 60S ribosomal protein L35 × 1 （P42766） 60S ribosomal protein L23a × 1 （P62750） 60S ribosomal protein L19 × 1 （P84098） 60S ribosomal protein L28 × 1 （P46779） Large ribosomal subunit protein eL22 × 1 （P35268） 60S ribosomal protein L17 × 1 （P18621） INOSITOL HEXAKISPHOSPHATE × 2	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL31_HUMAN
Isoform	—
PDB entities	14
Chains and sequence ranges	Author chain Ld； PDBConstruct 1–125； UniProt 1–125

60S ribosomal protein L17

Homo sapiens

UniProt P18621

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 15 RNA 2	N-alpha-acetyltransferase 10 × 2 （P41227） N-alpha-acetyltransferase 15, NatA auxiliary subunit × 2 （Q9BXJ9） 28S rRNA × 1 5.8S rRNA × 1 60S ribosomal protein L4 × 1 （P36578） Large ribosomal subunit protein eL6 × 1 （Q02878） 60S ribosomal protein L38 × 1 （P63173） Large ribosomal subunit protein uL24 × 1 （P61254） 60S ribosomal protein L35 × 1 （P42766） 60S ribosomal protein L23a × 1 （P62750） 60S ribosomal protein L19 × 1 （P84098） 60S ribosomal protein L28 × 1 （P46779） Large ribosomal subunit protein eL22 × 1 （P35268） 60S ribosomal protein L31 × 1 （P62899） INOSITOL HEXAKISPHOSPHATE × 2	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL17_HUMAN
Isoform	—
PDB entities	15
Chains and sequence ranges	Author chain LP； PDBConstruct 1–184； UniProt 1–184

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id	9gj6
Deposition date deposition_date	2024-08-21
Structure title title	Human 80S ribosome in complex with NatA in proximal and distal position
Keywords keywords	human 80S ribosome, N-terminal acetylation (NTA), N-acety-transferase A (NatA) in proximal and distal position, TRANSLATION; TRANSLATION
Experimental Method method	ELECTRON MICROSCOPY

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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

9gj6__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

9gj6__assembly_1__model_1 | I(q)

100 plotted points; both axes use logarithmic scales.

9gj6__assembly_1__model_1 | P(r) · Pending

P(r) will be calculated and displayed separately for the same assembly/model.

Rg（Guinier）	74.75 Å
Rg (electron density)	73.91 Å
Total Rg	74.10 Å
Atom count	43288
Residues	4294
Excluded volume	726040 Å³
Maximum q	0.500 Å⁻¹

Assembly	Model	Structure unit	Oligomeric description	Status	CRYSOL	Actions
1	1	`9gj6__assembly_1__model_1`	17-meric （17）	Success	4.1.3-1-20251215 (887e7ef)	View Download

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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (16)

Entity 1 Entity 1 polymer

Description description	N-alpha-acetyltransferase 10
Molecular weight formula_weight	26496.6 kDa
EC 编号 ec_number	2.3.1.255
Source method src_method	man
Copy count entity_count	2

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	A,C
Atom count atom_count	43288

MNIRNARPEDLMNMQHCNLLCLPENYQMKYYFYHGLSWPQLSYIAEDENGKIVGYVLAKMEEDPDDVPHGHITSLAVKRSHRRLGLAQKLMDQASRAMIENFNAKYVSLHVRKSNRAALHLYSNTLNFQISEVEPKYYADGEDAYAMKRDLTQMADELRRHLELKEKGRHVVLGAIENKVESKGNSPPSSGEACREEKGLAAEDSGGDSKDLSEVSETTESTDVKDSSEASDSAS

Source Source

Source organism organism	Homo sapiens
Common name common_name	human
NCBI taxonomy ID ncbi_taxonomy_id	9606
Host organism host_organism	Homo sapiens

Entity 2 Entity 2 polymer

Description description	N-alpha-acetyltransferase 15, NatA auxiliary subunit
Molecular weight formula_weight	98658.6 kDa
Source method src_method	man
Copy count entity_count	2

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	D,B

MPAVSLPPKENALFKRILRCYEHKQYRNGLKFCKQILSNPKFAEHGETLAMKGLTLNCLGKKEEAYELVRRGLRNDLKSHVCWHVYGLLQRSDKKYDEAIKCYRNALKWDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPAQRASWIGYAIAYHLLEDYEMAAKILEEFRKTQQTSPDKVDYEYSELLLYQNQVLREAGLYREALEHLCTYEKQICDKLAVEETKGELLLQLCRLEDAADVYRGLQERNPENWAYYKGLEKALKPANMLERLKIYEEAWTKYPRGLVPRRLPLNFLSGEKFKECLDKFLRMNFSKGCPPVFNTLRSLYKDKEKVAIIEELVVGYETSLKSCRLFNPNDDGKEEPPTTLLWVQYYLAQHYDKIGQPSIALEYINTAIESTPTLIELFLVKAKIYKHAGNIKEAARWMDEAQALDTADRFINSKCAKYMLKANLIKEAEEMCSKFTREGTSAVENLNEMQCMWFQTECAQAYKAMNKFGEALKKCHEIERHFIEITDDQFDFHTYCMRKITLRSYVDLLKLEDVLRQHPFYFKAARIAIEIYLKLHDNPLTDENKEHEADTANMSDKELKKLRNKQRRAQKKAQIEEEKKNAEKEKQQRNQKKKKDDDDEEIGGPKEELIPEKLAKVETPLEEAIKFLTPLKNLVKNKIETHLFAFEIYFRKEKFLLMLQSVKRAFAIDSSHPWLHECMIRLFNTVCESKDLSDTVRTVLKQEMNRLFGATNPKNFNETFLKRNSDSLPHRLSAAKMVYYLDPSSQKRAIELATTLDESLTNRNLQTCMEVLEALYDGSLGDCKEAAEIYRANCHKLFPYALAFMPP

Source Source

Source organism organism	Homo sapiens
Common name common_name	human
NCBI taxonomy ID ncbi_taxonomy_id	9606
Host organism host_organism	Homo sapiens

Entity 3 Entity 3 polymer

Description description	28S rRNA
Molecular weight formula_weight	1640222.1 kDa
Source method src_method	man
Copy count entity_count	1

Polymer Polymer

Polymer type type	polyribonucleotide
Chain IDs strand_id	1

CGCGACCUCAGAUCAGACGUGGCGACCCGCUGAAUUUAAGCAUAUUAGUCAGCGGAGGAGAAGAAACUAACCAGGAUUCCCUCAGUAACGGCGAGUGAACAGGGAAGAGCCCAGCGCCGAAUCCCCGCCCCGCGGCGGGGCGCGGGACAUGUGGCGUACGGAAGACCCGCUCCCCGGCGCCGCUCGUGGGGGGCCCAAGUCCUUCUGAUCGAGGCCCAGCCCGUGGACGGUGUGAGGCCGGUAGCGGCCCCCGGCGCGCCGGGCCCGGGUCUUCCCGGAGUCGGGUUGCUUGGGAAUGCAGCCCAAAGCGGGUGGUAAACUCCAUCUAAGGCUAAAUACCGGCACGAGACCGAUAGUCAACAAGUACCGUAAGGGAAAGUUGAAAAGAACUUUGAAGAGAGAGUUCAAGAGGGCGUGAAACCGUUAAGAGGUAAACGGGUGGGGUCCGCGCAGUCCGCCCGGAGGAUUCAACCCGGCGGCGGGUCCGGCCGUGUCGGCGGCCCGGCGGAUCUUUCCCGCCCCCCGUUCCUCCCGACCCCUCCACCCGCCCUCCCUUCCCCCGCCGCCCCUCCUCCUCCUCCCCGGAGGGGGCGGGCUCCGGCGGGUGCGGGGGUGGGCGGGCGGGGCCGGGGGUGGGGUCGGCGGGGGACCGUCCCCCGACCGGCGACCGGCCGCCGCCGGGCGCAUUUCCACCGCGGCGGUGCGCCGCGACCGGCUCCGGGACGGCUGGGAAGGCCCGGCGGGGAAGGUGGCUCGGGGGGCCCCGUCCGUCCGUCCGUCCGUCCUCCUCCUCCCCCGUCUCCGCCCCCCGGCCCCGCGUCCUCCCUCGGGAGGGCGCGCGGGUCGGGGCGGCGGCGGCGGCGGCGGUGGCGGCGGCGGCGGCGGCGGCGGGACCGAAACCCCCCCCGAGUGUUACAGCCCCCCCGGCAGCAGCACUCGCCGAAUCCCGGGGCCGAGGGAGCGAGACCCGUCGCCGCGCUCUCCCCCCUCCCGGCGCCCACCCCCGCGGGGAAUCCCCCGCGAGGGGGGUCUCCCCCGCGGGGGCGCGCCGGCGUCUCCUCGUGGGGGGGCCGGGCCACCCCUCCCACGGCGCGACCGCUCUCCCACCCCUCCUCCCCGCGCCCCCGCCCCGGCGACGGGGGGGGUGCCGCGCGCGGGUCGGGGGGCGGGGCGGACUGUCCCCAGUGCGCCCCGGGCGGGUCGCGCCGUCGGGCCCGGGGGAGGUUCUCUCGGGGCCACGCGCGCGUCCCCCGAAGAGGGGGACGGCGGAGCGAGCGCACGGGGUCGGCGGCGACGUCGGCUACCCACCCGACCCGUCUUGAAACACGGACCAAGGAGUCUAACACGUGCGCGAGUCGGGGGCUCGCACGAAAGCCGCCGUGGCGCAAUGAAGGUGAAGGCCGGCGCGCUCGCCGGCCGAGGUGGGAUCCCGAGGCCUCUCCAGUCCGCCGAGGGCGCACCACCGGCCCGUCUCGCCCGCCGCGCCGGGGAGGUGGAGCACGAGCGCACGUGUUAGGACCCGAAAGAUGGUGAACUAUGCCUGGGCAGGGCGAAGCCAGAGGAAACUCUGGUGGAGGUCCGUAGCGGUCCUGACGUGCAAAUCGGUCGUCCGACCUGGGUAUAGGGGCGAAAGACUAAUCGAACCAUCUAGUAGCUGGUUCCCUCCGAAGUUUCCCUCAGGAUAGCUGGCGCUCUCGCAGACCCGACGCACCCCCGCCACGCAGUUUUAUCCGGUAAAGCGAAUGAUUAGAGGUCUUGGGGCCGAAACGAUCUCAACCUAUUCUCAAACUUUAAAUGGGUAAGAAGCCCGGCUCGCUGGCGUGGAGCCGGGCGUGGAAUGCGAGUGCCUAGUGGGCCACUUUUGGUAAGCAGAACUGGCGCUGCGGGAUGAACCGAACGCCGGGUUAAGGCGCCCGAUGCCGACGCUCAUCAGACCCCAGAAAAGGUGUUGGUUGAUAUAGACAGCAGGACGGUGGCCAUGGAAGUCGGAAUCCGCUAAGGAGUGUGUAACAACUCACCUGCCGAAUCAACUAGCCCUGAAAAUGGAUGGCGCUGGAGCGUCGGGCCCAUACCCGGCCGUCGCCGGCAGUCGAGAGUGGACGGGAGCGGCGGGGGCGGCGCGCGCGCGCGCGCGUGUGGUGUGCGUCGGAGGGCGGCGGCGGCGGCGGCGGCGGGGGUGUGGGGUCCUUCCCCCGCCCCCCCCCCCACGCCUCCUCCCCUCCUCCCGCCCACGCCCCGCUCCCCGCCCCCGGAGCCCCGCGGACGCUACGCCGCGACGAGUAGGAGGGCCGCUGCGGUGAGCCUUGAAGCCUAGGGCGCGGGCCCGGGUGGAGCCGCCGCAGGUGCAGAUCUUGGUGGUAGUAGCAAAUAUUCAAACGAGAACUUUGAAGGCCGAAGUGGAGAAGGGUUCCAUGUGAACAGCAGUUGAACAUGGGUCAGUCGGUCCUGAGAGAUGGGCGAGCGCCGUUCCGAAGGGACGGGCGAUGGCCUCCGUUGCCCUCGGCCGAUCGAAAGGGAGUCGGGUUCAGAUCCCCGAAUCCGGAGUGGCGGAGAUGGGCGCCGCGAGGCGUCCAGUGCGGUAACGCGACCGAUCCCGGAGAAGCCGGCGGGAGCCCCGGGGAGAGUUCUCUUUUCUUUGUGAAGGGCAGGGCGCCCUGGAAUGGGUUCGCCCCGAGAGAGGGGCCCGUGCCUUGGAAAGCGUCGCGGUUCCGGCGGCGUCCGGUGAGCUCUCGCUGGCCCUUGAAAAUCCGGGGGAGAGGGUGUAAAUCUCGCGCCGGGCCGUACCCAUAUCCGCAGCAGGUCUCCAAGGUGAACAGCCUCUGGCAUGUUGGAACAAUGUAGGUAAGGGAAGUCGGCAAGCCGGAUCCGUAACUUCGGGAUAAGGAUUGGCUCUAAGGGCUGGGUCGGUCGGGCUGGGGCGCGAAGCGGGGCUGGGCGCGCGCCGCGGCUGGACGAGGCGCCGCCGCCCCCCCCACGCCCGGGGCACCCCCCUCGCGGCCCUCCCCCGCCCCACCCCGCGCGCGCCGCUCGCUCCCUCCCCGCCCCGCGCCCUCUCUCUCUCUCUCUCCCCCGCUCCCCGUCCUCCCCCCUCCCCGGGGGAGCGCCGCGUGGGGGCGGCGGCGGGGGGAGAAGGGUCGGGGCGGCAGGGGCCGGCGGCGGCCCGCCGCGGGGCCCCGGCGGCGGGGGCACGGUCCCCCGCGAGGGGGGCCCGGGCACCCGGGGGGCCGGCGGCGGCGGCGACUCUGGACGCGAGCCGGGCCCUUCCCGUGGAUCGCCCCAGCUGCGGCGGGCGUCGCGGCCGCCCCCGGGGAGCCCGGCGGGCGCCGGCGCGCCCCCCCCCCCACCCCACGUCUCGUCGCGCGCGCGUCCGCUGGGGGCGGGGAGCGGUCGGGCGGCGGCGGUCGGCGGGCGGCGGGGCGGGGCGGUUCGUCCCCCCGCCCUACCCCCCCGGCCCCGUCCGCCCCCCGUUCCCCCCUCCUCCUCGGCGCGCGGCGGCGGCGGCGGCAGGCGGCGGAGGGGCCGCGGGCCGGUCCCCCCCGCCGGGUCCGCCCCCGGGGCCGCGGUUCCGCGCGGCGCCUCGCCUCGGCCGGCGCCUAGCAGCCGACUUAGAACUGGUGCGGACCAGGGGAAUCCGACUGUUUAAUUAAAACAAAGCAUCGCGAAGGCCCGCGGCGGGUGUUGACGCGAUGUGAUUUCUGCCCAGUGCUCUGAAUGUCAAAGUGAAGAAAUUCAAUGAAGCGCGGGUAAACGGCGGGAGUAACUAUGACUCUCUUAAGGUAGCCAAAUGCCUCGUCAUCUAAUUAGUGACGCGCAUGAAUGGAUGAACGAGAUUCCCACUGUCCCUACCUACUAUCCAGCGAAACCACAGCCAAGGGAACGGGCUUGGCGGAAUCAGCGGGGAAAGAAGACCCUGUUGAGCUUGACUCUAGUCUGGCACGGUGAAGAGACAUGAGAGGUGUAGAAUAAGUGGGAGGCCCCCGGCGCCCCCCCGGUGUCCCCGCGAGGGGCCCGGGGCGGGGUCCGCCGGCCCUGCGGGCCGCCGGUGAAAUACCACUACUCUGAUCGUUUUUUCACUGACCCGGUGAGGCGGGGGGGCGAGCCCCGAGGGGCUCUCGCUUCUGGCGCCAAGCGCCCGGCCGCGCGCCGGCCGGGCGCGACCCGCUCCGGGGACAGUGCCAGGUGGGGAGUUUGACUGGGGCGGUACACCUGUCAAACGGUAACGCAGGUGUCCUAAGGCGAGCUCAGGGAGGACAGAAACCUCCCGUGGAGCAGAAGGGCAAAAGCUCGCUUGAUCUUGAUUUUCAGUACGAAUACAGACCGUGAAAGCGGGGCCUCACGAUCCUUCUGACCUUUUGGGUUUUAAGCAGGAGGUGUCAGAAAAGUUACCACAGGGAUAACUGGCUUGUGGCGGCCAAGCGUUCAUAGCGACGUCGCUUUUUGAUCCUUCGAUGUCGGCUCUUCCUAUCAUUGUGAAGCAGAAUUCACCAAGCGUUGGAUUGUUCACCCACUAAUAGGGAACGUGAGCUGGGUUUAGACCGUCGUGAGACAGGUUAGUUUUACCCUACUGAUGAUGUGUUGUUGCCAUGGUAAUCCUGCUCAGUACGAGAGGAACCGCAGGUUCAGACAUUUGGUGUAUGUGCUUGGCUGAGGAGCCAAUGGGGCGAAGCUACCAUCUGUGGGAUUAUGACUGAACGCCUCUAAGUCAGAAUCCCGCCCAGGCGGAACGAUACGGCAGCGCCGCGGAGCCUCGGUUGGCCUCGGAUAGCCGGUCCCCCGCCUGUCCCCGCCGGCGGGCCGCCCCCCCCCUCCACGCGCCCCGCGCGCGCGGGAGGGCGCGUGCCCCGCCGCGCGCCGGGACCGGGGUCCGGUGCGGAGUGCCCUUCGUCCUGGGAAACGGGGCGCGGCCGGAGAGGCGGCCGCCCCCUCGCCCGUCACGCACCGCACGUUCGUGGGGAACCUGGCGCUAAACCAUUCGUAGACGACCUGCUUCUGGGUCGGGGUUUCGUACGUAGCAGAGCAGCUCCCUCGCUGCGAUCUAUUGAAAGUCAGCCCUCGACACAAGGGUUUGUC

Source Source

Source organism organism	Homo sapiens
Common name common_name	human
NCBI taxonomy ID ncbi_taxonomy_id	9606
Host organism host_organism	Homo sapiens

Entity 4 Entity 4 polymer

Description description	5.8S rRNA
Molecular weight formula_weight	50449.8 kDa
Source method src_method	man
Copy count entity_count	1

Polymer Polymer

Polymer type type	polyribonucleotide
Chain IDs strand_id	8

CGACUCUUAGCGGUGGAUCACUCGGCUCGUGCGUCGAUGAAGAACGCAGCUAGCUGCGAGAAUUAAUGUGAAUUGCAGGACACAUUGAUCAUCGACACUUCGAACGCACUUGCGGCCCCGGGUUCCUCCCGGGGCUACGCCUGUCUGAGCGUCGCUU

Source Source

Source organism organism	Homo sapiens
Common name common_name	human
NCBI taxonomy ID ncbi_taxonomy_id	9606
Host organism host_organism	Homo sapiens

Entity 5 Entity 5 polymer

Description description	60S ribosomal protein L4
Molecular weight formula_weight	47804.6 kDa
Source method src_method	man
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	LC

MACARPLISVYSEKGESSGKNVTLPAVFKAPIRPDIVNFVHTNLRKNNRQPYAVSELAGHQTSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMFAPTKTWRRWHRRVNTTQKRYAICSALAASALPALVMSKGHRIEEVPELPLVVEDKVEGYKKTKEAVLLLKKLKAWNDIKKVYASQRMRAGKGKMRNRRRIQRRGPCIIYNEDNGIIKAFRNIPGITLLNVSKLNILKLAPGGHVGRFCIWTESAFRKLDELYGTWRKAASLKSNYNLPMHKMINTDLSRILKSPEIQRALRAPRKKIHRRVLKKNPLKNLRIMLKLNPYAKTMRRNTILRQARNHKLRVDKAAAAAAALQAKSDEKAAVAGKKPVVGKKGKKAAVGVKKQKKPLVGKKAAATKKPAPEKKPAEKKPTTEEKKPAA

Source Source

Source organism organism	Homo sapiens
Common name common_name	human
NCBI taxonomy ID ncbi_taxonomy_id	9606
Host organism host_organism	Homo sapiens

Entity 6 Entity 6 polymer

Description description	Large ribosomal subunit protein eL6
Molecular weight formula_weight	32810.2 kDa
Source method src_method	man
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	LE

MAGEKVEKPDTKEKKPEAKKVDAGGKVKKGNLKAKKPKKGKPHCSRNPVLVRGIGRYSRSAMYSRKAMYKRKYSAAKSKVEKKKKEKVLATVTKPVGGDKNGGTRVVKLRKMPRYYPTEDVPRKLLSHGKKPFSQHVRKLRASITPGTILIILTGRHRGKRVVFLKQLASGLLLVTGPLVLNRVPLRRTHQKFVIATSTKIDISNVKIPKHLTDAYFKKKKLRKPRHQEGEIFDTEKEKYEITEQRKIDQKAVDSQILPKIKAIPQLQGYLRSVFALTNGIYPHKLVF

Source Source

Source organism organism	Homo sapiens
Common name common_name	human
NCBI taxonomy ID ncbi_taxonomy_id	9606
Host organism host_organism	Homo sapiens

Entity 7 Entity 7 polymer

Description description	60S ribosomal protein L38
Molecular weight formula_weight	8238.9 kDa
Source method src_method	man
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	Lk

MPRKIEEIKDFLLTARRKDAKSVKIKKNKDNVKFKVRCSRYLYTLVITDKEKAEKLKQSLPPGLAVKELK

Source Source

Source organism organism	Homo sapiens
Common name common_name	human
NCBI taxonomy ID ncbi_taxonomy_id	9606
Host organism host_organism	Homo sapiens

Entity 8 Entity 8 polymer

Description description	Large ribosomal subunit protein uL24
Molecular weight formula_weight	17303.4 kDa
Source method src_method	man
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	LY

MKFNPFVTSDRSKNRKRHFNAPSHIRRKIMSSPLSKELRQKYNVRSMPIRKDDEVQVVRGHYKGQQIGKVVQVYRKKYVIYIERVQREKANGTTVHVGIHPSKVVITRLKLDKDRKKILERKAKSRQVGKEKGKYKEETIEKMQE

Source Source

Source organism organism	Homo sapiens
Common name common_name	human
NCBI taxonomy ID ncbi_taxonomy_id	9606
Host organism host_organism	Homo sapiens

Entity 9 Entity 9 polymer

Description description	60S ribosomal protein L35
Molecular weight formula_weight	14462.4 kDa
Source method src_method	man
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	Lh

AKIKARDLRGKKKEELLKQLDDLKVELSQLRVAKVTGGAASKLSKIRVVRKSIARVLTVINQTQKENLRKFYKGKKYKPLDLRPKKTRAMRRRLNKHEENLKTKKQQRKERLYPLRKYAVKA

Source Source

Source organism organism	Homo sapiens
Common name common_name	human
NCBI taxonomy ID ncbi_taxonomy_id	9606
Host organism host_organism	Homo sapiens

Entity 10 Entity 10 polymer

Description description	60S ribosomal protein L23a
Molecular weight formula_weight	17740.2 kDa
Source method src_method	man
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	LX

MAPKAKKEAPAPPKAEAKAKALKAKKAVLKGVHSHKKKKIRTSPTFRRPKTLRLRRQPKYPRKSAPRRNKLDHYAIIKFPLTTESAMKKIEDNNTLVFIVDVKANKHQIKQAVKKLYDIDVAKVNTLIRPDGEKKAYVRLAPDYDALDVANKIGII

Source Source

Source organism organism	Homo sapiens
Common name common_name	human
NCBI taxonomy ID ncbi_taxonomy_id	9606
Host organism host_organism	Homo sapiens

Entity 11 Entity 11 polymer

Description description	60S ribosomal protein L19
Molecular weight formula_weight	23535.3 kDa
Source method src_method	man
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	LR

MSMLRLQKRLASSVLRCGKKKVWLDPNETNEIANANSRQQIRKLIKDGLIIRKPVTVHSRARCRKNTLARRKGRHMGIGKRKGTANARMPEKVTWMRRMRILRRLLRRYRESKKIDRHMYHSLYLKVKGNVFKNKRILMEHIHKLKADKARKKLLADQAEARRSKTKEARKRREERLQAKKEEIIKTLSKEEETKK

Source Source

Source organism organism	Homo sapiens
Common name common_name	human
NCBI taxonomy ID ncbi_taxonomy_id	9606
Host organism host_organism	Homo sapiens

Entity 12 Entity 12 polymer

Description description	60S ribosomal protein L28
Molecular weight formula_weight	15784.6 kDa
Source method src_method	man
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	Lr

MSAHLQWMVVRNCSSFLIKRNKQTYSTEPNNLKARNSFRYNGLIHRKTVGVEPAADGKGVVVVIKRRSGQRKPATSYVRTTINKNARATLSSIRHMIRKNKYRPDLRMAAIRRASAILRSQKPVMVKRKRTRPTKSS

Source Source

Source organism organism	Homo sapiens
Common name common_name	human
NCBI taxonomy ID ncbi_taxonomy_id	9606
Host organism host_organism	Homo sapiens

Entity 13 Entity 13 polymer

Description description	Large ribosomal subunit protein eL22
Molecular weight formula_weight	14681.8 kDa
Source method src_method	man
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	LU

APVKKLVVKGGKKKKQVLKFTLDCTHPVEDGIMDAANFEQFLQERIKVNGKAGNLGGGVVTIERSKSKITVTSEVPFSKRYLKYLTKKYLKKNNLRDWLRVVANSKESYELRYFQINQDEEEEEDED

Source Source

Source organism organism	Homo sapiens
Common name common_name	human
NCBI taxonomy ID ncbi_taxonomy_id	9606
Host organism host_organism	Homo sapiens

Entity 14 Entity 14 polymer

Description description	60S ribosomal protein L31
Molecular weight formula_weight	14494.9 kDa
Source method src_method	man
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	Ld

MAPAKKGGEKKKGRSAINEVVTREYTINIHKRIHGVGFKKRAPRALKEIRKFAMKEMGTPDVRIDTRLNKAVWAKGIRNVPYRIRVRLSRKRNEDEDSPNKLYTLVTYVPVTTFKNLQTVNVDEN

Source Source

Source organism organism	Homo sapiens
Common name common_name	human
NCBI taxonomy ID ncbi_taxonomy_id	9606
Host organism host_organism	Homo sapiens

Entity 15 Entity 15 polymer

Description description	60S ribosomal protein L17
Molecular weight formula_weight	21443.2 kDa
Source method src_method	man
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	LP

MVRYSLDPENPTKSCKSRGSNLRVHFKNTRETAQAIKGMHIRKATKYLKDVTLQKQCVPFRRYNGGVGRCAQAKQWGWTQGRWPKKSAEFLLHMLKNAESNAELKGLDVDSLVIEHIQVNKAPKMRRRTYRAHGRINPYMSSPCHIEMILTEKEQIVPKPEEEVAQKKKISQKKLKKQKLMARE

Source Source

Source organism organism	Homo sapiens
Common name common_name	human
NCBI taxonomy ID ncbi_taxonomy_id	9606
Host organism host_organism	Homo sapiens

Entity 16 Entity 16 non-polymer

Description description	INOSITOL HEXAKISPHOSPHATE
Molecular weight formula_weight	660.0 kDa
Source method src_method	syn
Copy count entity_count	2

▶

Unit-cell length a length_a	1.000 Å
Unit-cell length b length_b	1.000 Å
Unit-cell length c length_c	1.000 Å
Unit-cell angle α angle_alpha	90.00 °
Unit-cell angle β angle_beta	90.00 °
Unit-cell angle γ angle_gamma	90.00 °
Molecules per unit cell Z z_pdb	—

Space group space_group	P 1
Space-group number int_tables_number	1
Crystal system crystal_system	—

Resolution resolution	3.91 Å
Resolution测定Method resolution_method	—
颗粒数 num_particles	17765

Human 80S ribosome in complex with NatA in proximal and distal position

1. Protein Identity and Related Structures Protein Identity & Related Structures

N-alpha-acetyltransferase 10

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

N-alpha-acetyltransferase 15, NatA auxiliary subunit

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

60S ribosomal protein L4

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

Large ribosomal subunit protein eL6

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

60S ribosomal protein L38

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

Large ribosomal subunit protein uL24

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

60S ribosomal protein L35

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

60S ribosomal protein L23a

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

60S ribosomal protein L19

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

60S ribosomal protein L28

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer