8r09

Cryo-EM structure of the cross-exon pre-B+5'ss+ATPgammaS complex

Method: ELECTRON MICROSCOPY
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1. Protein Identity and Related Structures Protein Identity & Related Structures

U6 snRNA-associated Sm-like protein LSm6

OrganismNot specified

UniProt P62312

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 54 RNA 6 U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 4 × 1 (Q15427) pre-mRNA × 1 Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U2 snRNA × 1 Splicing factor 3B subunit 3 × 1 (Q15393) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Small nuclear ribonucleoprotein Sm D2 × 3 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 3 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 3 (P14678) Small nuclear ribonucleoprotein Sm D3 × 3 (P62318) Small nuclear ribonucleoprotein G × 3 (P62308) Small nuclear ribonucleoprotein E × 3 (P62304) Small nuclear ribonucleoprotein Sm D1 × 3 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) Peptidyl-prolyl cis-trans isomerase H × 1 (O43447) Probable ATP-dependent RNA helicase DDX23 × 1 (Q9BUQ8) U4/U6 small nuclear ribonucleoprotein Prp3 × 1 (O43395) U4/U6 small nuclear ribonucleoprotein Prp31 × 1 (Q8WWY3) U4/U6 small nuclear ribonucleoprotein Prp4 × 1 (O43172) Pre-mRNA-processing factor 6 × 1 (O94906) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Ubiquitin carboxyl-terminal hydrolase 39 × 1 (Q53GS9) U4/U6.U5 tri-snRNP-associated protein 1 × 1 (O43290) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) NHP2-like protein 1, N-terminally processed × 1 (P55769) Thioredoxin-like protein 4A × 1 (P83876) U5 snRNA × 1 ;5'ss oligo ; × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U4 snRNA × 1 U6 snRNA × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name LSM6_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain 66; PDBConstruct 1–80; UniProt 1–80

U6 snRNA-associated Sm-like protein LSm7

OrganismNot specified

UniProt Q9UK45

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 54 RNA 6 U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 4 × 1 (Q15427) pre-mRNA × 1 Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U2 snRNA × 1 Splicing factor 3B subunit 3 × 1 (Q15393) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Small nuclear ribonucleoprotein Sm D2 × 3 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 3 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 3 (P14678) Small nuclear ribonucleoprotein Sm D3 × 3 (P62318) Small nuclear ribonucleoprotein G × 3 (P62308) Small nuclear ribonucleoprotein E × 3 (P62304) Small nuclear ribonucleoprotein Sm D1 × 3 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) Peptidyl-prolyl cis-trans isomerase H × 1 (O43447) Probable ATP-dependent RNA helicase DDX23 × 1 (Q9BUQ8) U4/U6 small nuclear ribonucleoprotein Prp3 × 1 (O43395) U4/U6 small nuclear ribonucleoprotein Prp31 × 1 (Q8WWY3) U4/U6 small nuclear ribonucleoprotein Prp4 × 1 (O43172) Pre-mRNA-processing factor 6 × 1 (O94906) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Ubiquitin carboxyl-terminal hydrolase 39 × 1 (Q53GS9) U4/U6.U5 tri-snRNP-associated protein 1 × 1 (O43290) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) NHP2-like protein 1, N-terminally processed × 1 (P55769) Thioredoxin-like protein 4A × 1 (P83876) U5 snRNA × 1 ;5'ss oligo ; × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U4 snRNA × 1 U6 snRNA × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name LSM7_HUMAN
Isoform —
PDB entities 2
Chains and sequence ranges Author chain 67; PDBConstruct 1–103; UniProt 1–103

U6 snRNA-associated Sm-like protein LSm2

OrganismNot specified

UniProt Q9Y333

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 54 RNA 6 U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 4 × 1 (Q15427) pre-mRNA × 1 Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U2 snRNA × 1 Splicing factor 3B subunit 3 × 1 (Q15393) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Small nuclear ribonucleoprotein Sm D2 × 3 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 3 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 3 (P14678) Small nuclear ribonucleoprotein Sm D3 × 3 (P62318) Small nuclear ribonucleoprotein G × 3 (P62308) Small nuclear ribonucleoprotein E × 3 (P62304) Small nuclear ribonucleoprotein Sm D1 × 3 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) Peptidyl-prolyl cis-trans isomerase H × 1 (O43447) Probable ATP-dependent RNA helicase DDX23 × 1 (Q9BUQ8) U4/U6 small nuclear ribonucleoprotein Prp3 × 1 (O43395) U4/U6 small nuclear ribonucleoprotein Prp31 × 1 (Q8WWY3) U4/U6 small nuclear ribonucleoprotein Prp4 × 1 (O43172) Pre-mRNA-processing factor 6 × 1 (O94906) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Ubiquitin carboxyl-terminal hydrolase 39 × 1 (Q53GS9) U4/U6.U5 tri-snRNP-associated protein 1 × 1 (O43290) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) NHP2-like protein 1, N-terminally processed × 1 (P55769) Thioredoxin-like protein 4A × 1 (P83876) U5 snRNA × 1 ;5'ss oligo ; × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U4 snRNA × 1 U6 snRNA × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name LSM2_HUMAN
Isoform —
PDB entities 3
Chains and sequence ranges Author chain 62; PDBConstruct 1–95; UniProt 1–95

U6 snRNA-associated Sm-like protein LSm3

OrganismNot specified

UniProt P62310

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 54 RNA 6 U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 4 × 1 (Q15427) pre-mRNA × 1 Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U2 snRNA × 1 Splicing factor 3B subunit 3 × 1 (Q15393) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Small nuclear ribonucleoprotein Sm D2 × 3 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 3 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 3 (P14678) Small nuclear ribonucleoprotein Sm D3 × 3 (P62318) Small nuclear ribonucleoprotein G × 3 (P62308) Small nuclear ribonucleoprotein E × 3 (P62304) Small nuclear ribonucleoprotein Sm D1 × 3 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) Peptidyl-prolyl cis-trans isomerase H × 1 (O43447) Probable ATP-dependent RNA helicase DDX23 × 1 (Q9BUQ8) U4/U6 small nuclear ribonucleoprotein Prp3 × 1 (O43395) U4/U6 small nuclear ribonucleoprotein Prp31 × 1 (Q8WWY3) U4/U6 small nuclear ribonucleoprotein Prp4 × 1 (O43172) Pre-mRNA-processing factor 6 × 1 (O94906) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Ubiquitin carboxyl-terminal hydrolase 39 × 1 (Q53GS9) U4/U6.U5 tri-snRNP-associated protein 1 × 1 (O43290) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) NHP2-like protein 1, N-terminally processed × 1 (P55769) Thioredoxin-like protein 4A × 1 (P83876) U5 snRNA × 1 ;5'ss oligo ; × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U4 snRNA × 1 U6 snRNA × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name LSM3_HUMAN
Isoform —
PDB entities 4
Chains and sequence ranges Author chain 63; PDBConstruct 1–102; UniProt 1–102

U6 snRNA-associated Sm-like protein LSm8

OrganismNot specified

UniProt O95777

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 54 RNA 6 U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 4 × 1 (Q15427) pre-mRNA × 1 Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U2 snRNA × 1 Splicing factor 3B subunit 3 × 1 (Q15393) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Small nuclear ribonucleoprotein Sm D2 × 3 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 3 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 3 (P14678) Small nuclear ribonucleoprotein Sm D3 × 3 (P62318) Small nuclear ribonucleoprotein G × 3 (P62308) Small nuclear ribonucleoprotein E × 3 (P62304) Small nuclear ribonucleoprotein Sm D1 × 3 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) Peptidyl-prolyl cis-trans isomerase H × 1 (O43447) Probable ATP-dependent RNA helicase DDX23 × 1 (Q9BUQ8) U4/U6 small nuclear ribonucleoprotein Prp3 × 1 (O43395) U4/U6 small nuclear ribonucleoprotein Prp31 × 1 (Q8WWY3) U4/U6 small nuclear ribonucleoprotein Prp4 × 1 (O43172) Pre-mRNA-processing factor 6 × 1 (O94906) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Ubiquitin carboxyl-terminal hydrolase 39 × 1 (Q53GS9) U4/U6.U5 tri-snRNP-associated protein 1 × 1 (O43290) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) NHP2-like protein 1, N-terminally processed × 1 (P55769) Thioredoxin-like protein 4A × 1 (P83876) U5 snRNA × 1 ;5'ss oligo ; × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U4 snRNA × 1 U6 snRNA × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name LSM8_HUMAN
Isoform —
PDB entities 5
Chains and sequence ranges Author chain 68; PDBConstruct 1–96; UniProt 1–96

U6 snRNA-associated Sm-like protein LSm4

OrganismNot specified

UniProt Q9Y4Z0

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 54 RNA 6 U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 4 × 1 (Q15427) pre-mRNA × 1 Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U2 snRNA × 1 Splicing factor 3B subunit 3 × 1 (Q15393) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Small nuclear ribonucleoprotein Sm D2 × 3 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 3 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 3 (P14678) Small nuclear ribonucleoprotein Sm D3 × 3 (P62318) Small nuclear ribonucleoprotein G × 3 (P62308) Small nuclear ribonucleoprotein E × 3 (P62304) Small nuclear ribonucleoprotein Sm D1 × 3 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) Peptidyl-prolyl cis-trans isomerase H × 1 (O43447) Probable ATP-dependent RNA helicase DDX23 × 1 (Q9BUQ8) U4/U6 small nuclear ribonucleoprotein Prp3 × 1 (O43395) U4/U6 small nuclear ribonucleoprotein Prp31 × 1 (Q8WWY3) U4/U6 small nuclear ribonucleoprotein Prp4 × 1 (O43172) Pre-mRNA-processing factor 6 × 1 (O94906) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Ubiquitin carboxyl-terminal hydrolase 39 × 1 (Q53GS9) U4/U6.U5 tri-snRNP-associated protein 1 × 1 (O43290) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) NHP2-like protein 1, N-terminally processed × 1 (P55769) Thioredoxin-like protein 4A × 1 (P83876) U5 snRNA × 1 ;5'ss oligo ; × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U4 snRNA × 1 U6 snRNA × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name LSM4_HUMAN
Isoform —
PDB entities 6
Chains and sequence ranges Author chain 64; PDBConstruct 1–139; UniProt 1–139

U6 snRNA-associated Sm-like protein LSm5

OrganismNot specified

UniProt Q9Y4Y9

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 54 RNA 6 U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 4 × 1 (Q15427) pre-mRNA × 1 Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U2 snRNA × 1 Splicing factor 3B subunit 3 × 1 (Q15393) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Small nuclear ribonucleoprotein Sm D2 × 3 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 3 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 3 (P14678) Small nuclear ribonucleoprotein Sm D3 × 3 (P62318) Small nuclear ribonucleoprotein G × 3 (P62308) Small nuclear ribonucleoprotein E × 3 (P62304) Small nuclear ribonucleoprotein Sm D1 × 3 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) Peptidyl-prolyl cis-trans isomerase H × 1 (O43447) Probable ATP-dependent RNA helicase DDX23 × 1 (Q9BUQ8) U4/U6 small nuclear ribonucleoprotein Prp3 × 1 (O43395) U4/U6 small nuclear ribonucleoprotein Prp31 × 1 (Q8WWY3) U4/U6 small nuclear ribonucleoprotein Prp4 × 1 (O43172) Pre-mRNA-processing factor 6 × 1 (O94906) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Ubiquitin carboxyl-terminal hydrolase 39 × 1 (Q53GS9) U4/U6.U5 tri-snRNP-associated protein 1 × 1 (O43290) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) NHP2-like protein 1, N-terminally processed × 1 (P55769) Thioredoxin-like protein 4A × 1 (P83876) U5 snRNA × 1 ;5'ss oligo ; × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U4 snRNA × 1 U6 snRNA × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name LSM5_HUMAN
Isoform —
PDB entities 7
Chains and sequence ranges Author chain 65; PDBConstruct 1–91; UniProt 1–91

U5 small nuclear ribonucleoprotein 40 kDa protein

OrganismNot specified

UniProt Q96DI7

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 54 RNA 6 U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) Splicing factor 3B subunit 4 × 1 (Q15427) pre-mRNA × 1 Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U2 snRNA × 1 Splicing factor 3B subunit 3 × 1 (Q15393) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Small nuclear ribonucleoprotein Sm D2 × 3 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 3 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 3 (P14678) Small nuclear ribonucleoprotein Sm D3 × 3 (P62318) Small nuclear ribonucleoprotein G × 3 (P62308) Small nuclear ribonucleoprotein E × 3 (P62304) Small nuclear ribonucleoprotein Sm D1 × 3 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) Peptidyl-prolyl cis-trans isomerase H × 1 (O43447) Probable ATP-dependent RNA helicase DDX23 × 1 (Q9BUQ8) U4/U6 small nuclear ribonucleoprotein Prp3 × 1 (O43395) U4/U6 small nuclear ribonucleoprotein Prp31 × 1 (Q8WWY3) U4/U6 small nuclear ribonucleoprotein Prp4 × 1 (O43172) Pre-mRNA-processing factor 6 × 1 (O94906) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Ubiquitin carboxyl-terminal hydrolase 39 × 1 (Q53GS9) U4/U6.U5 tri-snRNP-associated protein 1 × 1 (O43290) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) NHP2-like protein 1, N-terminally processed × 1 (P55769) Thioredoxin-like protein 4A × 1 (P83876) U5 snRNA × 1 ;5'ss oligo ; × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U4 snRNA × 1 U6 snRNA × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SNR40_HUMAN
Isoform —
PDB entities 8
Chains and sequence ranges Author chain E; PDBConstruct 1–357; UniProt 1–357

Splicing factor 3B subunit 4

OrganismNot specified

UniProt Q15427

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 54 RNA 6 U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) pre-mRNA × 1 Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U2 snRNA × 1 Splicing factor 3B subunit 3 × 1 (Q15393) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Small nuclear ribonucleoprotein Sm D2 × 3 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 3 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 3 (P14678) Small nuclear ribonucleoprotein Sm D3 × 3 (P62318) Small nuclear ribonucleoprotein G × 3 (P62308) Small nuclear ribonucleoprotein E × 3 (P62304) Small nuclear ribonucleoprotein Sm D1 × 3 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) Peptidyl-prolyl cis-trans isomerase H × 1 (O43447) Probable ATP-dependent RNA helicase DDX23 × 1 (Q9BUQ8) U4/U6 small nuclear ribonucleoprotein Prp3 × 1 (O43395) U4/U6 small nuclear ribonucleoprotein Prp31 × 1 (Q8WWY3) U4/U6 small nuclear ribonucleoprotein Prp4 × 1 (O43172) Pre-mRNA-processing factor 6 × 1 (O94906) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Ubiquitin carboxyl-terminal hydrolase 39 × 1 (Q53GS9) U4/U6.U5 tri-snRNP-associated protein 1 × 1 (O43290) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) NHP2-like protein 1, N-terminally processed × 1 (P55769) Thioredoxin-like protein 4A × 1 (P83876) U5 snRNA × 1 ;5'ss oligo ; × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U4 snRNA × 1 U6 snRNA × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SF3B4_HUMAN
Isoform —
PDB entities 9
Chains and sequence ranges Author chain B4; PDBConstruct 1–424; UniProt 1–424

Splicing factor 3A subunit 2

OrganismNot specified

UniProt Q15428

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 54 RNA 6 U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 4 × 1 (Q15427) pre-mRNA × 1 Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U2 snRNA × 1 Splicing factor 3B subunit 3 × 1 (Q15393) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Small nuclear ribonucleoprotein Sm D2 × 3 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 3 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 3 (P14678) Small nuclear ribonucleoprotein Sm D3 × 3 (P62318) Small nuclear ribonucleoprotein G × 3 (P62308) Small nuclear ribonucleoprotein E × 3 (P62304) Small nuclear ribonucleoprotein Sm D1 × 3 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) Peptidyl-prolyl cis-trans isomerase H × 1 (O43447) Probable ATP-dependent RNA helicase DDX23 × 1 (Q9BUQ8) U4/U6 small nuclear ribonucleoprotein Prp3 × 1 (O43395) U4/U6 small nuclear ribonucleoprotein Prp31 × 1 (Q8WWY3) U4/U6 small nuclear ribonucleoprotein Prp4 × 1 (O43172) Pre-mRNA-processing factor 6 × 1 (O94906) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Ubiquitin carboxyl-terminal hydrolase 39 × 1 (Q53GS9) U4/U6.U5 tri-snRNP-associated protein 1 × 1 (O43290) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) NHP2-like protein 1, N-terminally processed × 1 (P55769) Thioredoxin-like protein 4A × 1 (P83876) U5 snRNA × 1 ;5'ss oligo ; × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U4 snRNA × 1 U6 snRNA × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SF3A2_HUMAN
Isoform —
PDB entities 11
Chains and sequence ranges Author chain 8; PDBConstruct 1–464; UniProt 1–464

Splicing factor 3A subunit 3

OrganismNot specified

UniProt Q12874

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 54 RNA 6 U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 4 × 1 (Q15427) pre-mRNA × 1 Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U2 snRNA × 1 Splicing factor 3B subunit 3 × 1 (Q15393) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Small nuclear ribonucleoprotein Sm D2 × 3 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 3 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 3 (P14678) Small nuclear ribonucleoprotein Sm D3 × 3 (P62318) Small nuclear ribonucleoprotein G × 3 (P62308) Small nuclear ribonucleoprotein E × 3 (P62304) Small nuclear ribonucleoprotein Sm D1 × 3 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) Peptidyl-prolyl cis-trans isomerase H × 1 (O43447) Probable ATP-dependent RNA helicase DDX23 × 1 (Q9BUQ8) U4/U6 small nuclear ribonucleoprotein Prp3 × 1 (O43395) U4/U6 small nuclear ribonucleoprotein Prp31 × 1 (Q8WWY3) U4/U6 small nuclear ribonucleoprotein Prp4 × 1 (O43172) Pre-mRNA-processing factor 6 × 1 (O94906) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Ubiquitin carboxyl-terminal hydrolase 39 × 1 (Q53GS9) U4/U6.U5 tri-snRNP-associated protein 1 × 1 (O43290) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) NHP2-like protein 1, N-terminally processed × 1 (P55769) Thioredoxin-like protein 4A × 1 (P83876) U5 snRNA × 1 ;5'ss oligo ; × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U4 snRNA × 1 U6 snRNA × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SF3A3_HUMAN
Isoform —
PDB entities 12
Chains and sequence ranges Author chain 9; PDBConstruct 1–501; UniProt 1–501

Splicing factor 3B subunit 2

OrganismNot specified

UniProt Q13435

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 54 RNA 6 U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 4 × 1 (Q15427) pre-mRNA × 1 Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U2 snRNA × 1 Splicing factor 3B subunit 3 × 1 (Q15393) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Small nuclear ribonucleoprotein Sm D2 × 3 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 3 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 3 (P14678) Small nuclear ribonucleoprotein Sm D3 × 3 (P62318) Small nuclear ribonucleoprotein G × 3 (P62308) Small nuclear ribonucleoprotein E × 3 (P62304) Small nuclear ribonucleoprotein Sm D1 × 3 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) Peptidyl-prolyl cis-trans isomerase H × 1 (O43447) Probable ATP-dependent RNA helicase DDX23 × 1 (Q9BUQ8) U4/U6 small nuclear ribonucleoprotein Prp3 × 1 (O43395) U4/U6 small nuclear ribonucleoprotein Prp31 × 1 (Q8WWY3) U4/U6 small nuclear ribonucleoprotein Prp4 × 1 (O43172) Pre-mRNA-processing factor 6 × 1 (O94906) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Ubiquitin carboxyl-terminal hydrolase 39 × 1 (Q53GS9) U4/U6.U5 tri-snRNP-associated protein 1 × 1 (O43290) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) NHP2-like protein 1, N-terminally processed × 1 (P55769) Thioredoxin-like protein 4A × 1 (P83876) U5 snRNA × 1 ;5'ss oligo ; × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U4 snRNA × 1 U6 snRNA × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SF3B2_HUMAN
Isoform —
PDB entities 13
Chains and sequence ranges Author chain B2; PDBConstruct 1–895; UniProt 1–895

Splicing factor 3B subunit 5

OrganismNot specified

UniProt Q9BWJ5

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 54 RNA 6 U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 4 × 1 (Q15427) pre-mRNA × 1 Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 2 × 1 (Q13435) U2 snRNA × 1 Splicing factor 3B subunit 3 × 1 (Q15393) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Small nuclear ribonucleoprotein Sm D2 × 3 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 3 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 3 (P14678) Small nuclear ribonucleoprotein Sm D3 × 3 (P62318) Small nuclear ribonucleoprotein G × 3 (P62308) Small nuclear ribonucleoprotein E × 3 (P62304) Small nuclear ribonucleoprotein Sm D1 × 3 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) Peptidyl-prolyl cis-trans isomerase H × 1 (O43447) Probable ATP-dependent RNA helicase DDX23 × 1 (Q9BUQ8) U4/U6 small nuclear ribonucleoprotein Prp3 × 1 (O43395) U4/U6 small nuclear ribonucleoprotein Prp31 × 1 (Q8WWY3) U4/U6 small nuclear ribonucleoprotein Prp4 × 1 (O43172) Pre-mRNA-processing factor 6 × 1 (O94906) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Ubiquitin carboxyl-terminal hydrolase 39 × 1 (Q53GS9) U4/U6.U5 tri-snRNP-associated protein 1 × 1 (O43290) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) NHP2-like protein 1, N-terminally processed × 1 (P55769) Thioredoxin-like protein 4A × 1 (P83876) U5 snRNA × 1 ;5'ss oligo ; × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U4 snRNA × 1 U6 snRNA × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SF3B5_HUMAN
Isoform —
PDB entities 14
Chains and sequence ranges Author chain B5; PDBConstruct 1–86; UniProt 1–86

Splicing factor 3B subunit 3

OrganismNot specified

UniProt Q15393

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 54 RNA 6 U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 4 × 1 (Q15427) pre-mRNA × 1 Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U2 snRNA × 1 PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Small nuclear ribonucleoprotein Sm D2 × 3 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 3 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 3 (P14678) Small nuclear ribonucleoprotein Sm D3 × 3 (P62318) Small nuclear ribonucleoprotein G × 3 (P62308) Small nuclear ribonucleoprotein E × 3 (P62304) Small nuclear ribonucleoprotein Sm D1 × 3 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) Peptidyl-prolyl cis-trans isomerase H × 1 (O43447) Probable ATP-dependent RNA helicase DDX23 × 1 (Q9BUQ8) U4/U6 small nuclear ribonucleoprotein Prp3 × 1 (O43395) U4/U6 small nuclear ribonucleoprotein Prp31 × 1 (Q8WWY3) U4/U6 small nuclear ribonucleoprotein Prp4 × 1 (O43172) Pre-mRNA-processing factor 6 × 1 (O94906) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Ubiquitin carboxyl-terminal hydrolase 39 × 1 (Q53GS9) U4/U6.U5 tri-snRNP-associated protein 1 × 1 (O43290) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) NHP2-like protein 1, N-terminally processed × 1 (P55769) Thioredoxin-like protein 4A × 1 (P83876) U5 snRNA × 1 ;5'ss oligo ; × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U4 snRNA × 1 U6 snRNA × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SF3B3_HUMAN
Isoform —
PDB entities 16
Chains and sequence ranges Author chain B3; PDBConstruct 1–1217; UniProt 1–1217

PHD finger-like domain-containing protein 5A

OrganismNot specified

UniProt Q7RTV0

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 54 RNA 6 U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 4 × 1 (Q15427) pre-mRNA × 1 Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U2 snRNA × 1 Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Small nuclear ribonucleoprotein Sm D2 × 3 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 3 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 3 (P14678) Small nuclear ribonucleoprotein Sm D3 × 3 (P62318) Small nuclear ribonucleoprotein G × 3 (P62308) Small nuclear ribonucleoprotein E × 3 (P62304) Small nuclear ribonucleoprotein Sm D1 × 3 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) Peptidyl-prolyl cis-trans isomerase H × 1 (O43447) Probable ATP-dependent RNA helicase DDX23 × 1 (Q9BUQ8) U4/U6 small nuclear ribonucleoprotein Prp3 × 1 (O43395) U4/U6 small nuclear ribonucleoprotein Prp31 × 1 (Q8WWY3) U4/U6 small nuclear ribonucleoprotein Prp4 × 1 (O43172) Pre-mRNA-processing factor 6 × 1 (O94906) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Ubiquitin carboxyl-terminal hydrolase 39 × 1 (Q53GS9) U4/U6.U5 tri-snRNP-associated protein 1 × 1 (O43290) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) NHP2-like protein 1, N-terminally processed × 1 (P55769) Thioredoxin-like protein 4A × 1 (P83876) U5 snRNA × 1 ;5'ss oligo ; × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U4 snRNA × 1 U6 snRNA × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name PHF5A_HUMAN
Isoform —
PDB entities 17
Chains and sequence ranges Author chain BP; PDBConstruct 1–110; UniProt 1–110

Splicing factor 3B subunit 1

OrganismNot specified

UniProt O75533

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 54 RNA 6 U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 4 × 1 (Q15427) pre-mRNA × 1 Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U2 snRNA × 1 Splicing factor 3B subunit 3 × 1 (Q15393) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Small nuclear ribonucleoprotein Sm D2 × 3 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 3 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 3 (P14678) Small nuclear ribonucleoprotein Sm D3 × 3 (P62318) Small nuclear ribonucleoprotein G × 3 (P62308) Small nuclear ribonucleoprotein E × 3 (P62304) Small nuclear ribonucleoprotein Sm D1 × 3 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) Peptidyl-prolyl cis-trans isomerase H × 1 (O43447) Probable ATP-dependent RNA helicase DDX23 × 1 (Q9BUQ8) U4/U6 small nuclear ribonucleoprotein Prp3 × 1 (O43395) U4/U6 small nuclear ribonucleoprotein Prp31 × 1 (Q8WWY3) U4/U6 small nuclear ribonucleoprotein Prp4 × 1 (O43172) Pre-mRNA-processing factor 6 × 1 (O94906) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Ubiquitin carboxyl-terminal hydrolase 39 × 1 (Q53GS9) U4/U6.U5 tri-snRNP-associated protein 1 × 1 (O43290) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) NHP2-like protein 1, N-terminally processed × 1 (P55769) Thioredoxin-like protein 4A × 1 (P83876) U5 snRNA × 1 ;5'ss oligo ; × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U4 snRNA × 1 U6 snRNA × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SF3B1_HUMAN
Isoform —
PDB entities 18
Chains and sequence ranges Author chain B1; PDBConstruct 1–1304; UniProt 1–1304

Splicing factor 3B subunit 6

OrganismNot specified

UniProt Q9Y3B4

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 54 RNA 6 U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 4 × 1 (Q15427) pre-mRNA × 1 Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U2 snRNA × 1 Splicing factor 3B subunit 3 × 1 (Q15393) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 1 × 1 (O75533) Small nuclear ribonucleoprotein Sm D2 × 3 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 3 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 3 (P14678) Small nuclear ribonucleoprotein Sm D3 × 3 (P62318) Small nuclear ribonucleoprotein G × 3 (P62308) Small nuclear ribonucleoprotein E × 3 (P62304) Small nuclear ribonucleoprotein Sm D1 × 3 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) Peptidyl-prolyl cis-trans isomerase H × 1 (O43447) Probable ATP-dependent RNA helicase DDX23 × 1 (Q9BUQ8) U4/U6 small nuclear ribonucleoprotein Prp3 × 1 (O43395) U4/U6 small nuclear ribonucleoprotein Prp31 × 1 (Q8WWY3) U4/U6 small nuclear ribonucleoprotein Prp4 × 1 (O43172) Pre-mRNA-processing factor 6 × 1 (O94906) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Ubiquitin carboxyl-terminal hydrolase 39 × 1 (Q53GS9) U4/U6.U5 tri-snRNP-associated protein 1 × 1 (O43290) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) NHP2-like protein 1, N-terminally processed × 1 (P55769) Thioredoxin-like protein 4A × 1 (P83876) U5 snRNA × 1 ;5'ss oligo ; × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U4 snRNA × 1 U6 snRNA × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SF3B6_HUMAN
Isoform —
PDB entities 19
Chains and sequence ranges Author chain B6; PDBConstruct 1–125; UniProt 1–125

Small nuclear ribonucleoprotein Sm D2

OrganismNot specified

UniProt P62316

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 54 RNA 6 U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 4 × 1 (Q15427) pre-mRNA × 1 Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U2 snRNA × 1 Splicing factor 3B subunit 3 × 1 (Q15393) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 3 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 3 (P14678) Small nuclear ribonucleoprotein Sm D3 × 3 (P62318) Small nuclear ribonucleoprotein G × 3 (P62308) Small nuclear ribonucleoprotein E × 3 (P62304) Small nuclear ribonucleoprotein Sm D1 × 3 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) Peptidyl-prolyl cis-trans isomerase H × 1 (O43447) Probable ATP-dependent RNA helicase DDX23 × 1 (Q9BUQ8) U4/U6 small nuclear ribonucleoprotein Prp3 × 1 (O43395) U4/U6 small nuclear ribonucleoprotein Prp31 × 1 (Q8WWY3) U4/U6 small nuclear ribonucleoprotein Prp4 × 1 (O43172) Pre-mRNA-processing factor 6 × 1 (O94906) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Ubiquitin carboxyl-terminal hydrolase 39 × 1 (Q53GS9) U4/U6.U5 tri-snRNP-associated protein 1 × 1 (O43290) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) NHP2-like protein 1, N-terminally processed × 1 (P55769) Thioredoxin-like protein 4A × 1 (P83876) U5 snRNA × 1 ;5'ss oligo ; × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U4 snRNA × 1 U6 snRNA × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SMD2_HUMAN
Isoform —
PDB entities 20
Chains and sequence ranges Author chain 22; PDBConstruct 1–118; UniProt 1–118 Author chain 42; PDBConstruct 1–118; UniProt 1–118 Author chain 52; PDBConstruct 1–118; UniProt 1–118

;U2 small nuclear ribonucleoprotein B'' ;

OrganismNot specified

UniProt P08579

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 54 RNA 6 U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 4 × 1 (Q15427) pre-mRNA × 1 Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U2 snRNA × 1 Splicing factor 3B subunit 3 × 1 (Q15393) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Small nuclear ribonucleoprotein Sm D2 × 3 (P62316) Small nuclear ribonucleoprotein F × 3 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 3 (P14678) Small nuclear ribonucleoprotein Sm D3 × 3 (P62318) Small nuclear ribonucleoprotein G × 3 (P62308) Small nuclear ribonucleoprotein E × 3 (P62304) Small nuclear ribonucleoprotein Sm D1 × 3 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) Peptidyl-prolyl cis-trans isomerase H × 1 (O43447) Probable ATP-dependent RNA helicase DDX23 × 1 (Q9BUQ8) U4/U6 small nuclear ribonucleoprotein Prp3 × 1 (O43395) U4/U6 small nuclear ribonucleoprotein Prp31 × 1 (Q8WWY3) U4/U6 small nuclear ribonucleoprotein Prp4 × 1 (O43172) Pre-mRNA-processing factor 6 × 1 (O94906) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Ubiquitin carboxyl-terminal hydrolase 39 × 1 (Q53GS9) U4/U6.U5 tri-snRNP-associated protein 1 × 1 (O43290) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) NHP2-like protein 1, N-terminally processed × 1 (P55769) Thioredoxin-like protein 4A × 1 (P83876) U5 snRNA × 1 ;5'ss oligo ; × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U4 snRNA × 1 U6 snRNA × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name RU2B_HUMAN
Isoform —
PDB entities 21
Chains and sequence ranges Author chain 2B; PDBConstruct 1–225; UniProt 1–225

Small nuclear ribonucleoprotein F

OrganismNot specified

UniProt P62306

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 54 RNA 6 U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 4 × 1 (Q15427) pre-mRNA × 1 Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U2 snRNA × 1 Splicing factor 3B subunit 3 × 1 (Q15393) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Small nuclear ribonucleoprotein Sm D2 × 3 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 3 (P14678) Small nuclear ribonucleoprotein Sm D3 × 3 (P62318) Small nuclear ribonucleoprotein G × 3 (P62308) Small nuclear ribonucleoprotein E × 3 (P62304) Small nuclear ribonucleoprotein Sm D1 × 3 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) Peptidyl-prolyl cis-trans isomerase H × 1 (O43447) Probable ATP-dependent RNA helicase DDX23 × 1 (Q9BUQ8) U4/U6 small nuclear ribonucleoprotein Prp3 × 1 (O43395) U4/U6 small nuclear ribonucleoprotein Prp31 × 1 (Q8WWY3) U4/U6 small nuclear ribonucleoprotein Prp4 × 1 (O43172) Pre-mRNA-processing factor 6 × 1 (O94906) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Ubiquitin carboxyl-terminal hydrolase 39 × 1 (Q53GS9) U4/U6.U5 tri-snRNP-associated protein 1 × 1 (O43290) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) NHP2-like protein 1, N-terminally processed × 1 (P55769) Thioredoxin-like protein 4A × 1 (P83876) U5 snRNA × 1 ;5'ss oligo ; × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U4 snRNA × 1 U6 snRNA × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name RUXF_HUMAN
Isoform —
PDB entities 22
Chains and sequence ranges Author chain 2f; PDBConstruct 1–86; UniProt 1–86 Author chain 4f; PDBConstruct 1–86; UniProt 1–86 Author chain 5f; PDBConstruct 1–86; UniProt 1–86

;Small nuclear ribonucleoprotein-associated proteins B and B' ;

OrganismNot specified

UniProt P14678

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 54 RNA 6 U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 4 × 1 (Q15427) pre-mRNA × 1 Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U2 snRNA × 1 Splicing factor 3B subunit 3 × 1 (Q15393) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Small nuclear ribonucleoprotein Sm D2 × 3 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 3 (P62306) Small nuclear ribonucleoprotein Sm D3 × 3 (P62318) Small nuclear ribonucleoprotein G × 3 (P62308) Small nuclear ribonucleoprotein E × 3 (P62304) Small nuclear ribonucleoprotein Sm D1 × 3 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) Peptidyl-prolyl cis-trans isomerase H × 1 (O43447) Probable ATP-dependent RNA helicase DDX23 × 1 (Q9BUQ8) U4/U6 small nuclear ribonucleoprotein Prp3 × 1 (O43395) U4/U6 small nuclear ribonucleoprotein Prp31 × 1 (Q8WWY3) U4/U6 small nuclear ribonucleoprotein Prp4 × 1 (O43172) Pre-mRNA-processing factor 6 × 1 (O94906) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Ubiquitin carboxyl-terminal hydrolase 39 × 1 (Q53GS9) U4/U6.U5 tri-snRNP-associated protein 1 × 1 (O43290) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) NHP2-like protein 1, N-terminally processed × 1 (P55769) Thioredoxin-like protein 4A × 1 (P83876) U5 snRNA × 1 ;5'ss oligo ; × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U4 snRNA × 1 U6 snRNA × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name RSMB_HUMAN
Isoform —
PDB entities 23
Chains and sequence ranges Author chain 2b; PDBConstruct 1–240; UniProt 1–240 Author chain 4b; PDBConstruct 1–240; UniProt 1–240 Author chain 5b; PDBConstruct 1–240; UniProt 1–240

Small nuclear ribonucleoprotein Sm D3

OrganismNot specified

UniProt P62318

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 54 RNA 6 U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 4 × 1 (Q15427) pre-mRNA × 1 Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U2 snRNA × 1 Splicing factor 3B subunit 3 × 1 (Q15393) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Small nuclear ribonucleoprotein Sm D2 × 3 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 3 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 3 (P14678) Small nuclear ribonucleoprotein G × 3 (P62308) Small nuclear ribonucleoprotein E × 3 (P62304) Small nuclear ribonucleoprotein Sm D1 × 3 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) Peptidyl-prolyl cis-trans isomerase H × 1 (O43447) Probable ATP-dependent RNA helicase DDX23 × 1 (Q9BUQ8) U4/U6 small nuclear ribonucleoprotein Prp3 × 1 (O43395) U4/U6 small nuclear ribonucleoprotein Prp31 × 1 (Q8WWY3) U4/U6 small nuclear ribonucleoprotein Prp4 × 1 (O43172) Pre-mRNA-processing factor 6 × 1 (O94906) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Ubiquitin carboxyl-terminal hydrolase 39 × 1 (Q53GS9) U4/U6.U5 tri-snRNP-associated protein 1 × 1 (O43290) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) NHP2-like protein 1, N-terminally processed × 1 (P55769) Thioredoxin-like protein 4A × 1 (P83876) U5 snRNA × 1 ;5'ss oligo ; × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U4 snRNA × 1 U6 snRNA × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SMD3_HUMAN
Isoform —
PDB entities 24
Chains and sequence ranges Author chain 23; PDBConstruct 1–126; UniProt 1–126 Author chain 43; PDBConstruct 1–126; UniProt 1–126 Author chain 53; PDBConstruct 1–126; UniProt 1–126

Small nuclear ribonucleoprotein G

OrganismNot specified

UniProt P62308

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 54 RNA 6 U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 4 × 1 (Q15427) pre-mRNA × 1 Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U2 snRNA × 1 Splicing factor 3B subunit 3 × 1 (Q15393) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Small nuclear ribonucleoprotein Sm D2 × 3 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 3 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 3 (P14678) Small nuclear ribonucleoprotein Sm D3 × 3 (P62318) Small nuclear ribonucleoprotein E × 3 (P62304) Small nuclear ribonucleoprotein Sm D1 × 3 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) Peptidyl-prolyl cis-trans isomerase H × 1 (O43447) Probable ATP-dependent RNA helicase DDX23 × 1 (Q9BUQ8) U4/U6 small nuclear ribonucleoprotein Prp3 × 1 (O43395) U4/U6 small nuclear ribonucleoprotein Prp31 × 1 (Q8WWY3) U4/U6 small nuclear ribonucleoprotein Prp4 × 1 (O43172) Pre-mRNA-processing factor 6 × 1 (O94906) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Ubiquitin carboxyl-terminal hydrolase 39 × 1 (Q53GS9) U4/U6.U5 tri-snRNP-associated protein 1 × 1 (O43290) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) NHP2-like protein 1, N-terminally processed × 1 (P55769) Thioredoxin-like protein 4A × 1 (P83876) U5 snRNA × 1 ;5'ss oligo ; × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U4 snRNA × 1 U6 snRNA × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name RUXG_HUMAN
Isoform —
PDB entities 25
Chains and sequence ranges Author chain 2g; PDBConstruct 1–76; UniProt 1–76 Author chain 4g; PDBConstruct 1–76; UniProt 1–76 Author chain 5g; PDBConstruct 1–76; UniProt 1–76

Small nuclear ribonucleoprotein E

OrganismNot specified

UniProt P62304

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 54 RNA 6 U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 4 × 1 (Q15427) pre-mRNA × 1 Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U2 snRNA × 1 Splicing factor 3B subunit 3 × 1 (Q15393) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Small nuclear ribonucleoprotein Sm D2 × 3 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 3 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 3 (P14678) Small nuclear ribonucleoprotein Sm D3 × 3 (P62318) Small nuclear ribonucleoprotein G × 3 (P62308) Small nuclear ribonucleoprotein Sm D1 × 3 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) Peptidyl-prolyl cis-trans isomerase H × 1 (O43447) Probable ATP-dependent RNA helicase DDX23 × 1 (Q9BUQ8) U4/U6 small nuclear ribonucleoprotein Prp3 × 1 (O43395) U4/U6 small nuclear ribonucleoprotein Prp31 × 1 (Q8WWY3) U4/U6 small nuclear ribonucleoprotein Prp4 × 1 (O43172) Pre-mRNA-processing factor 6 × 1 (O94906) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Ubiquitin carboxyl-terminal hydrolase 39 × 1 (Q53GS9) U4/U6.U5 tri-snRNP-associated protein 1 × 1 (O43290) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) NHP2-like protein 1, N-terminally processed × 1 (P55769) Thioredoxin-like protein 4A × 1 (P83876) U5 snRNA × 1 ;5'ss oligo ; × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U4 snRNA × 1 U6 snRNA × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name RUXE_HUMAN
Isoform —
PDB entities 26
Chains and sequence ranges Author chain 2e; PDBConstruct 1–92; UniProt 1–92 Author chain 4e; PDBConstruct 1–92; UniProt 1–92 Author chain 5e; PDBConstruct 1–92; UniProt 1–92

Small nuclear ribonucleoprotein Sm D1

OrganismNot specified

UniProt P62314

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 54 RNA 6 U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 4 × 1 (Q15427) pre-mRNA × 1 Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U2 snRNA × 1 Splicing factor 3B subunit 3 × 1 (Q15393) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Small nuclear ribonucleoprotein Sm D2 × 3 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 3 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 3 (P14678) Small nuclear ribonucleoprotein Sm D3 × 3 (P62318) Small nuclear ribonucleoprotein G × 3 (P62308) Small nuclear ribonucleoprotein E × 3 (P62304) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) Peptidyl-prolyl cis-trans isomerase H × 1 (O43447) Probable ATP-dependent RNA helicase DDX23 × 1 (Q9BUQ8) U4/U6 small nuclear ribonucleoprotein Prp3 × 1 (O43395) U4/U6 small nuclear ribonucleoprotein Prp31 × 1 (Q8WWY3) U4/U6 small nuclear ribonucleoprotein Prp4 × 1 (O43172) Pre-mRNA-processing factor 6 × 1 (O94906) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Ubiquitin carboxyl-terminal hydrolase 39 × 1 (Q53GS9) U4/U6.U5 tri-snRNP-associated protein 1 × 1 (O43290) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) NHP2-like protein 1, N-terminally processed × 1 (P55769) Thioredoxin-like protein 4A × 1 (P83876) U5 snRNA × 1 ;5'ss oligo ; × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U4 snRNA × 1 U6 snRNA × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SMD1_HUMAN
Isoform —
PDB entities 27
Chains and sequence ranges Author chain 21; PDBConstruct 1–119; UniProt 1–119 Author chain 41; PDBConstruct 1–119; UniProt 1–119 Author chain 51; PDBConstruct 1–119; UniProt 1–119

;U2 small nuclear ribonucleoprotein A' ;

OrganismNot specified

UniProt P09661

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 54 RNA 6 U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 4 × 1 (Q15427) pre-mRNA × 1 Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U2 snRNA × 1 Splicing factor 3B subunit 3 × 1 (Q15393) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Small nuclear ribonucleoprotein Sm D2 × 3 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 3 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 3 (P14678) Small nuclear ribonucleoprotein Sm D3 × 3 (P62318) Small nuclear ribonucleoprotein G × 3 (P62308) Small nuclear ribonucleoprotein E × 3 (P62304) Small nuclear ribonucleoprotein Sm D1 × 3 (P62314) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) Peptidyl-prolyl cis-trans isomerase H × 1 (O43447) Probable ATP-dependent RNA helicase DDX23 × 1 (Q9BUQ8) U4/U6 small nuclear ribonucleoprotein Prp3 × 1 (O43395) U4/U6 small nuclear ribonucleoprotein Prp31 × 1 (Q8WWY3) U4/U6 small nuclear ribonucleoprotein Prp4 × 1 (O43172) Pre-mRNA-processing factor 6 × 1 (O94906) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Ubiquitin carboxyl-terminal hydrolase 39 × 1 (Q53GS9) U4/U6.U5 tri-snRNP-associated protein 1 × 1 (O43290) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) NHP2-like protein 1, N-terminally processed × 1 (P55769) Thioredoxin-like protein 4A × 1 (P83876) U5 snRNA × 1 ;5'ss oligo ; × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U4 snRNA × 1 U6 snRNA × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name RU2A_HUMAN
Isoform —
PDB entities 28
Chains and sequence ranges Author chain 2A; PDBConstruct 1–255; UniProt 1–255

U5 small nuclear ribonucleoprotein 200 kDa helicase

OrganismNot specified

UniProt O75643

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 54 RNA 6 U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 4 × 1 (Q15427) pre-mRNA × 1 Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U2 snRNA × 1 Splicing factor 3B subunit 3 × 1 (Q15393) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Small nuclear ribonucleoprotein Sm D2 × 3 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 3 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 3 (P14678) Small nuclear ribonucleoprotein Sm D3 × 3 (P62318) Small nuclear ribonucleoprotein G × 3 (P62308) Small nuclear ribonucleoprotein E × 3 (P62304) Small nuclear ribonucleoprotein Sm D1 × 3 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Peptidyl-prolyl cis-trans isomerase H × 1 (O43447) Probable ATP-dependent RNA helicase DDX23 × 1 (Q9BUQ8) U4/U6 small nuclear ribonucleoprotein Prp3 × 1 (O43395) U4/U6 small nuclear ribonucleoprotein Prp31 × 1 (Q8WWY3) U4/U6 small nuclear ribonucleoprotein Prp4 × 1 (O43172) Pre-mRNA-processing factor 6 × 1 (O94906) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Ubiquitin carboxyl-terminal hydrolase 39 × 1 (Q53GS9) U4/U6.U5 tri-snRNP-associated protein 1 × 1 (O43290) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) NHP2-like protein 1, N-terminally processed × 1 (P55769) Thioredoxin-like protein 4A × 1 (P83876) U5 snRNA × 1 ;5'ss oligo ; × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U4 snRNA × 1 U6 snRNA × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name U520_HUMAN
Isoform —
PDB entities 29
Chains and sequence ranges Author chain B; PDBConstruct 1–2136; UniProt 1–2136

Peptidyl-prolyl cis-trans isomerase H

OrganismNot specified

UniProt O43447

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 54 RNA 6 U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 4 × 1 (Q15427) pre-mRNA × 1 Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U2 snRNA × 1 Splicing factor 3B subunit 3 × 1 (Q15393) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Small nuclear ribonucleoprotein Sm D2 × 3 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 3 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 3 (P14678) Small nuclear ribonucleoprotein Sm D3 × 3 (P62318) Small nuclear ribonucleoprotein G × 3 (P62308) Small nuclear ribonucleoprotein E × 3 (P62304) Small nuclear ribonucleoprotein Sm D1 × 3 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) Probable ATP-dependent RNA helicase DDX23 × 1 (Q9BUQ8) U4/U6 small nuclear ribonucleoprotein Prp3 × 1 (O43395) U4/U6 small nuclear ribonucleoprotein Prp31 × 1 (Q8WWY3) U4/U6 small nuclear ribonucleoprotein Prp4 × 1 (O43172) Pre-mRNA-processing factor 6 × 1 (O94906) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Ubiquitin carboxyl-terminal hydrolase 39 × 1 (Q53GS9) U4/U6.U5 tri-snRNP-associated protein 1 × 1 (O43290) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) NHP2-like protein 1, N-terminally processed × 1 (P55769) Thioredoxin-like protein 4A × 1 (P83876) U5 snRNA × 1 ;5'ss oligo ; × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U4 snRNA × 1 U6 snRNA × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name PPIH_HUMAN
Isoform —
PDB entities 30
Chains and sequence ranges Author chain W; PDBConstruct 1–177; UniProt 1–177

Probable ATP-dependent RNA helicase DDX23

OrganismNot specified

UniProt Q9BUQ8

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 54 RNA 6 U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 4 × 1 (Q15427) pre-mRNA × 1 Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U2 snRNA × 1 Splicing factor 3B subunit 3 × 1 (Q15393) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Small nuclear ribonucleoprotein Sm D2 × 3 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 3 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 3 (P14678) Small nuclear ribonucleoprotein Sm D3 × 3 (P62318) Small nuclear ribonucleoprotein G × 3 (P62308) Small nuclear ribonucleoprotein E × 3 (P62304) Small nuclear ribonucleoprotein Sm D1 × 3 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) Peptidyl-prolyl cis-trans isomerase H × 1 (O43447) U4/U6 small nuclear ribonucleoprotein Prp3 × 1 (O43395) U4/U6 small nuclear ribonucleoprotein Prp31 × 1 (Q8WWY3) U4/U6 small nuclear ribonucleoprotein Prp4 × 1 (O43172) Pre-mRNA-processing factor 6 × 1 (O94906) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Ubiquitin carboxyl-terminal hydrolase 39 × 1 (Q53GS9) U4/U6.U5 tri-snRNP-associated protein 1 × 1 (O43290) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) NHP2-like protein 1, N-terminally processed × 1 (P55769) Thioredoxin-like protein 4A × 1 (P83876) U5 snRNA × 1 ;5'ss oligo ; × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U4 snRNA × 1 U6 snRNA × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name DDX23_HUMAN
Isoform —
PDB entities 31
Chains and sequence ranges Author chain G; PDBConstruct 1–820; UniProt 1–820

U4/U6 small nuclear ribonucleoprotein Prp3

OrganismNot specified

UniProt O43395

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 54 RNA 6 U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 4 × 1 (Q15427) pre-mRNA × 1 Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U2 snRNA × 1 Splicing factor 3B subunit 3 × 1 (Q15393) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Small nuclear ribonucleoprotein Sm D2 × 3 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 3 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 3 (P14678) Small nuclear ribonucleoprotein Sm D3 × 3 (P62318) Small nuclear ribonucleoprotein G × 3 (P62308) Small nuclear ribonucleoprotein E × 3 (P62304) Small nuclear ribonucleoprotein Sm D1 × 3 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) Peptidyl-prolyl cis-trans isomerase H × 1 (O43447) Probable ATP-dependent RNA helicase DDX23 × 1 (Q9BUQ8) U4/U6 small nuclear ribonucleoprotein Prp31 × 1 (Q8WWY3) U4/U6 small nuclear ribonucleoprotein Prp4 × 1 (O43172) Pre-mRNA-processing factor 6 × 1 (O94906) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Ubiquitin carboxyl-terminal hydrolase 39 × 1 (Q53GS9) U4/U6.U5 tri-snRNP-associated protein 1 × 1 (O43290) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) NHP2-like protein 1, N-terminally processed × 1 (P55769) Thioredoxin-like protein 4A × 1 (P83876) U5 snRNA × 1 ;5'ss oligo ; × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U4 snRNA × 1 U6 snRNA × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name PRPF3_HUMAN
Isoform —
PDB entities 32
Chains and sequence ranges Author chain J; PDBConstruct 1–683; UniProt 1–683

U4/U6 small nuclear ribonucleoprotein Prp31

OrganismNot specified

UniProt Q8WWY3

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 54 RNA 6 U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 4 × 1 (Q15427) pre-mRNA × 1 Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U2 snRNA × 1 Splicing factor 3B subunit 3 × 1 (Q15393) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Small nuclear ribonucleoprotein Sm D2 × 3 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 3 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 3 (P14678) Small nuclear ribonucleoprotein Sm D3 × 3 (P62318) Small nuclear ribonucleoprotein G × 3 (P62308) Small nuclear ribonucleoprotein E × 3 (P62304) Small nuclear ribonucleoprotein Sm D1 × 3 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) Peptidyl-prolyl cis-trans isomerase H × 1 (O43447) Probable ATP-dependent RNA helicase DDX23 × 1 (Q9BUQ8) U4/U6 small nuclear ribonucleoprotein Prp3 × 1 (O43395) U4/U6 small nuclear ribonucleoprotein Prp4 × 1 (O43172) Pre-mRNA-processing factor 6 × 1 (O94906) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Ubiquitin carboxyl-terminal hydrolase 39 × 1 (Q53GS9) U4/U6.U5 tri-snRNP-associated protein 1 × 1 (O43290) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) NHP2-like protein 1, N-terminally processed × 1 (P55769) Thioredoxin-like protein 4A × 1 (P83876) U5 snRNA × 1 ;5'ss oligo ; × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U4 snRNA × 1 U6 snRNA × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name PRP31_HUMAN
Isoform —
PDB entities 33
Chains and sequence ranges Author chain L; PDBConstruct 1–499; UniProt 1–499

U4/U6 small nuclear ribonucleoprotein Prp4

OrganismNot specified

UniProt O43172

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 54 RNA 6 U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 4 × 1 (Q15427) pre-mRNA × 1 Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U2 snRNA × 1 Splicing factor 3B subunit 3 × 1 (Q15393) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Small nuclear ribonucleoprotein Sm D2 × 3 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 3 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 3 (P14678) Small nuclear ribonucleoprotein Sm D3 × 3 (P62318) Small nuclear ribonucleoprotein G × 3 (P62308) Small nuclear ribonucleoprotein E × 3 (P62304) Small nuclear ribonucleoprotein Sm D1 × 3 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) Peptidyl-prolyl cis-trans isomerase H × 1 (O43447) Probable ATP-dependent RNA helicase DDX23 × 1 (Q9BUQ8) U4/U6 small nuclear ribonucleoprotein Prp3 × 1 (O43395) U4/U6 small nuclear ribonucleoprotein Prp31 × 1 (Q8WWY3) Pre-mRNA-processing factor 6 × 1 (O94906) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Ubiquitin carboxyl-terminal hydrolase 39 × 1 (Q53GS9) U4/U6.U5 tri-snRNP-associated protein 1 × 1 (O43290) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) NHP2-like protein 1, N-terminally processed × 1 (P55769) Thioredoxin-like protein 4A × 1 (P83876) U5 snRNA × 1 ;5'ss oligo ; × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U4 snRNA × 1 U6 snRNA × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name PRP4_HUMAN
Isoform —
PDB entities 34
Chains and sequence ranges Author chain F; PDBConstruct 1–522; UniProt 1–522

Pre-mRNA-processing factor 6

OrganismNot specified

UniProt O94906

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 54 RNA 6 U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 4 × 1 (Q15427) pre-mRNA × 1 Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U2 snRNA × 1 Splicing factor 3B subunit 3 × 1 (Q15393) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Small nuclear ribonucleoprotein Sm D2 × 3 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 3 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 3 (P14678) Small nuclear ribonucleoprotein Sm D3 × 3 (P62318) Small nuclear ribonucleoprotein G × 3 (P62308) Small nuclear ribonucleoprotein E × 3 (P62304) Small nuclear ribonucleoprotein Sm D1 × 3 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) Peptidyl-prolyl cis-trans isomerase H × 1 (O43447) Probable ATP-dependent RNA helicase DDX23 × 1 (Q9BUQ8) U4/U6 small nuclear ribonucleoprotein Prp3 × 1 (O43395) U4/U6 small nuclear ribonucleoprotein Prp31 × 1 (Q8WWY3) U4/U6 small nuclear ribonucleoprotein Prp4 × 1 (O43172) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Ubiquitin carboxyl-terminal hydrolase 39 × 1 (Q53GS9) U4/U6.U5 tri-snRNP-associated protein 1 × 1 (O43290) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) NHP2-like protein 1, N-terminally processed × 1 (P55769) Thioredoxin-like protein 4A × 1 (P83876) U5 snRNA × 1 ;5'ss oligo ; × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U4 snRNA × 1 U6 snRNA × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name PRP6_HUMAN
Isoform —
PDB entities 35
Chains and sequence ranges Author chain N; PDBConstruct 1–941; UniProt 1–941

Pre-mRNA-processing-splicing factor 8

OrganismNot specified

UniProt Q6P2Q9

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 54 RNA 6 U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 4 × 1 (Q15427) pre-mRNA × 1 Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U2 snRNA × 1 Splicing factor 3B subunit 3 × 1 (Q15393) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Small nuclear ribonucleoprotein Sm D2 × 3 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 3 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 3 (P14678) Small nuclear ribonucleoprotein Sm D3 × 3 (P62318) Small nuclear ribonucleoprotein G × 3 (P62308) Small nuclear ribonucleoprotein E × 3 (P62304) Small nuclear ribonucleoprotein Sm D1 × 3 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) Peptidyl-prolyl cis-trans isomerase H × 1 (O43447) Probable ATP-dependent RNA helicase DDX23 × 1 (Q9BUQ8) U4/U6 small nuclear ribonucleoprotein Prp3 × 1 (O43395) U4/U6 small nuclear ribonucleoprotein Prp31 × 1 (Q8WWY3) U4/U6 small nuclear ribonucleoprotein Prp4 × 1 (O43172) Pre-mRNA-processing factor 6 × 1 (O94906) Ubiquitin carboxyl-terminal hydrolase 39 × 1 (Q53GS9) U4/U6.U5 tri-snRNP-associated protein 1 × 1 (O43290) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) NHP2-like protein 1, N-terminally processed × 1 (P55769) Thioredoxin-like protein 4A × 1 (P83876) U5 snRNA × 1 ;5'ss oligo ; × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U4 snRNA × 1 U6 snRNA × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name PRP8_HUMAN
Isoform —
PDB entities 36
Chains and sequence ranges Author chain A; PDBConstruct 1–2335; UniProt 1–2335

Ubiquitin carboxyl-terminal hydrolase 39

OrganismNot specified

UniProt Q53GS9

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 54 RNA 6 U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 4 × 1 (Q15427) pre-mRNA × 1 Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U2 snRNA × 1 Splicing factor 3B subunit 3 × 1 (Q15393) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Small nuclear ribonucleoprotein Sm D2 × 3 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 3 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 3 (P14678) Small nuclear ribonucleoprotein Sm D3 × 3 (P62318) Small nuclear ribonucleoprotein G × 3 (P62308) Small nuclear ribonucleoprotein E × 3 (P62304) Small nuclear ribonucleoprotein Sm D1 × 3 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) Peptidyl-prolyl cis-trans isomerase H × 1 (O43447) Probable ATP-dependent RNA helicase DDX23 × 1 (Q9BUQ8) U4/U6 small nuclear ribonucleoprotein Prp3 × 1 (O43395) U4/U6 small nuclear ribonucleoprotein Prp31 × 1 (Q8WWY3) U4/U6 small nuclear ribonucleoprotein Prp4 × 1 (O43172) Pre-mRNA-processing factor 6 × 1 (O94906) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) U4/U6.U5 tri-snRNP-associated protein 1 × 1 (O43290) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) NHP2-like protein 1, N-terminally processed × 1 (P55769) Thioredoxin-like protein 4A × 1 (P83876) U5 snRNA × 1 ;5'ss oligo ; × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U4 snRNA × 1 U6 snRNA × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name UBP39_HUMAN
Isoform —
PDB entities 37
Chains and sequence ranges Author chain U; PDBConstruct 1–565; UniProt 1–565

U4/U6.U5 tri-snRNP-associated protein 1

OrganismNot specified

UniProt O43290

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 54 RNA 6 U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 4 × 1 (Q15427) pre-mRNA × 1 Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U2 snRNA × 1 Splicing factor 3B subunit 3 × 1 (Q15393) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Small nuclear ribonucleoprotein Sm D2 × 3 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 3 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 3 (P14678) Small nuclear ribonucleoprotein Sm D3 × 3 (P62318) Small nuclear ribonucleoprotein G × 3 (P62308) Small nuclear ribonucleoprotein E × 3 (P62304) Small nuclear ribonucleoprotein Sm D1 × 3 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) Peptidyl-prolyl cis-trans isomerase H × 1 (O43447) Probable ATP-dependent RNA helicase DDX23 × 1 (Q9BUQ8) U4/U6 small nuclear ribonucleoprotein Prp3 × 1 (O43395) U4/U6 small nuclear ribonucleoprotein Prp31 × 1 (Q8WWY3) U4/U6 small nuclear ribonucleoprotein Prp4 × 1 (O43172) Pre-mRNA-processing factor 6 × 1 (O94906) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Ubiquitin carboxyl-terminal hydrolase 39 × 1 (Q53GS9) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) NHP2-like protein 1, N-terminally processed × 1 (P55769) Thioredoxin-like protein 4A × 1 (P83876) U5 snRNA × 1 ;5'ss oligo ; × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U4 snRNA × 1 U6 snRNA × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SNUT1_HUMAN
Isoform —
PDB entities 38
Chains and sequence ranges Author chain S; PDBConstruct 1–800; UniProt 1–800

116 kDa U5 small nuclear ribonucleoprotein component

OrganismNot specified

UniProt Q15029

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 54 RNA 6 U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 4 × 1 (Q15427) pre-mRNA × 1 Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U2 snRNA × 1 Splicing factor 3B subunit 3 × 1 (Q15393) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Small nuclear ribonucleoprotein Sm D2 × 3 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 3 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 3 (P14678) Small nuclear ribonucleoprotein Sm D3 × 3 (P62318) Small nuclear ribonucleoprotein G × 3 (P62308) Small nuclear ribonucleoprotein E × 3 (P62304) Small nuclear ribonucleoprotein Sm D1 × 3 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) Peptidyl-prolyl cis-trans isomerase H × 1 (O43447) Probable ATP-dependent RNA helicase DDX23 × 1 (Q9BUQ8) U4/U6 small nuclear ribonucleoprotein Prp3 × 1 (O43395) U4/U6 small nuclear ribonucleoprotein Prp31 × 1 (Q8WWY3) U4/U6 small nuclear ribonucleoprotein Prp4 × 1 (O43172) Pre-mRNA-processing factor 6 × 1 (O94906) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Ubiquitin carboxyl-terminal hydrolase 39 × 1 (Q53GS9) U4/U6.U5 tri-snRNP-associated protein 1 × 1 (O43290) NHP2-like protein 1, N-terminally processed × 1 (P55769) Thioredoxin-like protein 4A × 1 (P83876) U5 snRNA × 1 ;5'ss oligo ; × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U4 snRNA × 1 U6 snRNA × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name U5S1_HUMAN
Isoform —
PDB entities 39
Chains and sequence ranges Author chain C; PDBConstruct 1–972; UniProt 1–972

NHP2-like protein 1, N-terminally processed

OrganismNot specified

UniProt P55769

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 54 RNA 6 U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 4 × 1 (Q15427) pre-mRNA × 1 Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U2 snRNA × 1 Splicing factor 3B subunit 3 × 1 (Q15393) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Small nuclear ribonucleoprotein Sm D2 × 3 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 3 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 3 (P14678) Small nuclear ribonucleoprotein Sm D3 × 3 (P62318) Small nuclear ribonucleoprotein G × 3 (P62308) Small nuclear ribonucleoprotein E × 3 (P62304) Small nuclear ribonucleoprotein Sm D1 × 3 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) Peptidyl-prolyl cis-trans isomerase H × 1 (O43447) Probable ATP-dependent RNA helicase DDX23 × 1 (Q9BUQ8) U4/U6 small nuclear ribonucleoprotein Prp3 × 1 (O43395) U4/U6 small nuclear ribonucleoprotein Prp31 × 1 (Q8WWY3) U4/U6 small nuclear ribonucleoprotein Prp4 × 1 (O43172) Pre-mRNA-processing factor 6 × 1 (O94906) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Ubiquitin carboxyl-terminal hydrolase 39 × 1 (Q53GS9) U4/U6.U5 tri-snRNP-associated protein 1 × 1 (O43290) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) Thioredoxin-like protein 4A × 1 (P83876) U5 snRNA × 1 ;5'ss oligo ; × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U4 snRNA × 1 U6 snRNA × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name NH2L1_HUMAN
Isoform —
PDB entities 40
Chains and sequence ranges Author chain M; PDBConstruct 1–128; UniProt 1–128

Thioredoxin-like protein 4A

OrganismNot specified

UniProt P83876

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 54 RNA 6 U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 4 × 1 (Q15427) pre-mRNA × 1 Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U2 snRNA × 1 Splicing factor 3B subunit 3 × 1 (Q15393) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Small nuclear ribonucleoprotein Sm D2 × 3 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 3 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 3 (P14678) Small nuclear ribonucleoprotein Sm D3 × 3 (P62318) Small nuclear ribonucleoprotein G × 3 (P62308) Small nuclear ribonucleoprotein E × 3 (P62304) Small nuclear ribonucleoprotein Sm D1 × 3 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) Peptidyl-prolyl cis-trans isomerase H × 1 (O43447) Probable ATP-dependent RNA helicase DDX23 × 1 (Q9BUQ8) U4/U6 small nuclear ribonucleoprotein Prp3 × 1 (O43395) U4/U6 small nuclear ribonucleoprotein Prp31 × 1 (Q8WWY3) U4/U6 small nuclear ribonucleoprotein Prp4 × 1 (O43172) Pre-mRNA-processing factor 6 × 1 (O94906) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Ubiquitin carboxyl-terminal hydrolase 39 × 1 (Q53GS9) U4/U6.U5 tri-snRNP-associated protein 1 × 1 (O43290) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) NHP2-like protein 1, N-terminally processed × 1 (P55769) U5 snRNA × 1 ;5'ss oligo ; × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U4 snRNA × 1 U6 snRNA × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name TXN4A_HUMAN
Isoform —
PDB entities 41
Chains and sequence ranges Author chain D; PDBConstruct 1–142; UniProt 1–142

Splicing factor 3A subunit 1

OrganismNot specified

UniProt Q15459

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 54 RNA 6 U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 4 × 1 (Q15427) pre-mRNA × 1 Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U2 snRNA × 1 Splicing factor 3B subunit 3 × 1 (Q15393) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Small nuclear ribonucleoprotein Sm D2 × 3 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 3 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 3 (P14678) Small nuclear ribonucleoprotein Sm D3 × 3 (P62318) Small nuclear ribonucleoprotein G × 3 (P62308) Small nuclear ribonucleoprotein E × 3 (P62304) Small nuclear ribonucleoprotein Sm D1 × 3 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) Peptidyl-prolyl cis-trans isomerase H × 1 (O43447) Probable ATP-dependent RNA helicase DDX23 × 1 (Q9BUQ8) U4/U6 small nuclear ribonucleoprotein Prp3 × 1 (O43395) U4/U6 small nuclear ribonucleoprotein Prp31 × 1 (Q8WWY3) U4/U6 small nuclear ribonucleoprotein Prp4 × 1 (O43172) Pre-mRNA-processing factor 6 × 1 (O94906) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Ubiquitin carboxyl-terminal hydrolase 39 × 1 (Q53GS9) U4/U6.U5 tri-snRNP-associated protein 1 × 1 (O43290) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) NHP2-like protein 1, N-terminally processed × 1 (P55769) Thioredoxin-like protein 4A × 1 (P83876) U5 snRNA × 1 ;5'ss oligo ; × 1 U4 snRNA × 1 U6 snRNA × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SF3A1_HUMAN
Isoform —
PDB entities 44
Chains and sequence ranges Author chain 7; PDBConstruct 1–793; UniProt 1–793

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id8r09
Deposition date deposition_date2023-10-31
Structure title titleCryo-EM structure of the cross-exon pre-B+5'ss+ATPgammaS complex
Keywords keywordsspliceosome, SPLICING; SPLICING
Experimental Method methodELECTRON MICROSCOPY
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

8r09__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

8r09__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 109 1010 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

8r09__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg(Guinier)0.00 Å
Rg (electron density)121.60 Å
Total Rg121.90 Å
Atom count82064
Residues14638
Excluded volume1322600 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 8r09__assembly_1__model_1 60-meric (60) Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (46)

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7. Citations (1)