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9cfx

Cryo-EM structure of myosin-1c bound to F-actin in the Rigor state

Method: ELECTRON MICROSCOPY
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Actin, alpha skeletal muscle

OrganismNot specified

UniProt P68135

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 5 Unconventional myosin-Ic × 1 （Q9WTI7） Calmodulin-1 × 1 （P0DP26） ADENOSINE-5'-DIPHOSPHATE × 3 MAGNESIUM ION × 3 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1ijj 1ijj 1j6z 1nwk 1qz5 1s22 1wua 2asm 2aso 2asp 2fxu 2gwj

40 assemblies; showing the first 12

Homodimer
1lcu 1rdw 1rfq 1yxq 2a5x 2gwk 2hmp 2q1n 2q1n 2q31 2q31 2q36

14 assemblies; showing the first 12

Homotetramer
8dmx 8ru0 9fjo

3 assemblies

Other homooligomers
2y83 3b5u 3g37 3j8i 3j8j 3j8k 3mfp 4a7n 5mva 5mvy 5onv 5ooc

42 assemblies; showing the first 12

Heteromeric or nucleic-acid complex
1eqy 1esv 1kxp 1lot 1m8q 1ma9 1mvw 1o18 1o19 1o1a 1o1b 1o1c

255 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name ACTS_RABIT
Isoform —
PDB entities 1
Chains and sequence ranges Author chain B； PDBConstruct 1–375； UniProt 3–377 Author chain C； PDBConstruct 1–375； UniProt 3–377 Author chain D； PDBConstruct 1–375； UniProt 3–377

Unconventional myosin-Ic

Mus musculus

UniProt Q9WTI7

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 5 Actin, alpha skeletal muscle × 3 （P68135） Calmodulin-1 × 1 （P0DP26） ADENOSINE-5'-DIPHOSPHATE × 3 MAGNESIUM ION × 3 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
4r8g 9cfu 9cfv 9cfw 9cfx

5 assemblies

View Construct and Data Evidence
UniProt name MYO1C_MOUSE
Isoform —
PDB entities 2
Chains and sequence ranges Author chain P； PDBConstruct 1–720； UniProt 36–755

Calmodulin-1

Mus musculus

UniProt P0DP26

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 5 Actin, alpha skeletal muscle × 3 （P68135） Unconventional myosin-Ic × 1 （Q9WTI7） ADENOSINE-5'-DIPHOSPHATE × 3 MAGNESIUM ION × 3 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
7b1g 7cqp 7yv9 8of8 8w41 9cfu 9cfv 9cfw 9cfx 9ijj

10 assemblies

View Construct and Data Evidence
UniProt name CALM1_MOUSE
Isoform —
PDB entities 3
Chains and sequence ranges Author chain R； PDBConstruct 1–148； UniProt 1–148

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id9cfx
Deposition date deposition_date2024-06-27
Structure title titleCryo-EM structure of myosin-1c bound to F-actin in the Rigor state
Keywords keywordsF-actin, myosin, myosin-1c, cellular motility, cryo-EM, actomyosin, MOTOR PROTEIN; MOTOR PROTEIN
Experimental Method methodELECTRON MICROSCOPY
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

9cfx__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

9cfx__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

9cfx__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）49.67 Å
Rg (electron density)50.12 Å
Total Rg50.13 Å
Atom count15749
Residues1972
Excluded volume279800 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 9cfx__assembly_1__model_1 pentameric （5） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (5)

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7. Citations (1)