7unc

Pol II-DSIF-SPT6-PAF1c-TFIIS complex with rewrapped nucleosome

Method: ELECTRON MICROSCOPY Dmax: 268.5 Å Quality: GOOD

1. Protein Identity and Related Structures Protein Identity & Related Structures

DNA-directed RNA polymerase subunit

OrganismNot specified

UniProt A0A7M4DUC2

State in the Current Structure

Assembly Oligomeric State Construct Mutations and Modifications Ligands, Ions and Associated Components Method and Experimental Conditions Structure Quality
1 Other combination Heteromer Protein × 29 DNA 2 RNA 1 PDB declaration: 32-meric(32) Consistent with all polymer counts Chain A; UniProt 1–1984 Non-standard monomer:Yes (specific site not provided by mmCIF) DNA-directed RNA polymerase subunit beta × 1 (A0A4X1TVZ5) DNA-directed RNA polymerase II subunit RPB3 × 1 (A0A481DF93) RPOL4c domain-containing protein × 1 (A0A8D1GCS3) DNA-directed RNA polymerase II subunit E × 1 (A0A4X1VTX4) DNA-directed RNA polymerases I, II, and III subunit RPABC2 × 1 (A0A4X1VEK9) DNA-directed RNA polymerase II subunit RPB7 × 1 (A0A4X1VKG7) RPB8 × 1 RPB9 × 1 RPB10 × 1 RPB11 × 1 RNA polymerase II subunit K × 1 (A0A4X1TRS6) Transcription elongation factor SPT6 × 1 (Q7KZ85) Non-template DNA × 1 Transcription elongation factor A protein 1 × 1 (P23193) RNA × 1 RNA polymerase-associated protein CTR9 homolog × 1 (Q6PD62) RNA polymerase-associated protein RTF1 homolog × 1 (Q92541) Template DNA × 1 RNA polymerase-associated protein LEO1 × 1 (Q8WVC0) RNA polymerase II-associated factor 1 homolog × 1 (Q8N7H5) WDR61 × 1 (Q9GZS3) Parafibromin × 1 (Q6P1J9) Transcription elongation factor SPT5 × 1 (O00267) Histone H3.2 × 2 (P84233) Histone H4 × 2 (P62799) Histone H2A × 2 (Q6AZJ8) Histone H2B 1.1 × 2 (P02281) ZN ZINC ION × 8 MG MAGNESIUM ION × 1 ELECTRON MICROSCOPY cryo-EM buffer:pH 7.4 cryo-EM vitrification conditions:Cryogen ETHANE Resolution 3.00 Å

Other States of the Same Protein in the Database

Each row is a biological assembly of the same UniProt protein in another PDB entry. The “Difference from current entry” column identifies evidence-level differences; no tag means the currently parsed fields agree.

22 other PDB entries and 22 assemblies. Open the comparison page and filter oligomeric states

View Construct and Data Evidence
UniProt name A0A7M4DUC2_PIG
Isoform
PDB entities 1
Chains and sequence ranges Author chain A; PDBConstruct 1–1984; UniProt 1–1984

DNA-directed RNA polymerase subunit beta

OrganismNot specified

UniProt A0A4X1TVZ5

State in the Current Structure

Assembly Oligomeric State Construct Mutations and Modifications Ligands, Ions and Associated Components Method and Experimental Conditions Structure Quality
1 Other combination Heteromer Protein × 29 DNA 2 RNA 1 PDB declaration: 32-meric(32) Consistent with all polymer counts Chain B; UniProt 1–1251 Not recorded DNA-directed RNA polymerase subunit × 1 (A0A7M4DUC2) DNA-directed RNA polymerase II subunit RPB3 × 1 (A0A481DF93) RPOL4c domain-containing protein × 1 (A0A8D1GCS3) DNA-directed RNA polymerase II subunit E × 1 (A0A4X1VTX4) DNA-directed RNA polymerases I, II, and III subunit RPABC2 × 1 (A0A4X1VEK9) DNA-directed RNA polymerase II subunit RPB7 × 1 (A0A4X1VKG7) RPB8 × 1 RPB9 × 1 RPB10 × 1 RPB11 × 1 RNA polymerase II subunit K × 1 (A0A4X1TRS6) Transcription elongation factor SPT6 × 1 (Q7KZ85) Non-template DNA × 1 Transcription elongation factor A protein 1 × 1 (P23193) RNA × 1 RNA polymerase-associated protein CTR9 homolog × 1 (Q6PD62) RNA polymerase-associated protein RTF1 homolog × 1 (Q92541) Template DNA × 1 RNA polymerase-associated protein LEO1 × 1 (Q8WVC0) RNA polymerase II-associated factor 1 homolog × 1 (Q8N7H5) WDR61 × 1 (Q9GZS3) Parafibromin × 1 (Q6P1J9) Transcription elongation factor SPT5 × 1 (O00267) Histone H3.2 × 2 (P84233) Histone H4 × 2 (P62799) Histone H2A × 2 (Q6AZJ8) Histone H2B 1.1 × 2 (P02281) ZN ZINC ION × 8 MG MAGNESIUM ION × 1 ELECTRON MICROSCOPY cryo-EM buffer:pH 7.4 cryo-EM vitrification conditions:Cryogen ETHANE Resolution 3.00 Å

Other States of the Same Protein in the Database

Each row is a biological assembly of the same UniProt protein in another PDB entry. The “Difference from current entry” column identifies evidence-level differences; no tag means the currently parsed fields agree.

47 other PDB entries and 47 assemblies. Open the comparison page and filter oligomeric states

View Construct and Data Evidence
UniProt name A0A4X1TVZ5_PIG
Isoform
PDB entities 2
Chains and sequence ranges Author chain B; PDBConstruct 1–1251; UniProt 1–1251

DNA-directed RNA polymerase II subunit RPB3

OrganismNot specified

UniProt A0A481DF93

State in the Current Structure

Assembly Oligomeric State Construct Mutations and Modifications Ligands, Ions and Associated Components Method and Experimental Conditions Structure Quality
1 Other combination Heteromer Protein × 29 DNA 2 RNA 1 PDB declaration: 32-meric(32) Consistent with all polymer counts Chain C; UniProt 46–320 Not recorded DNA-directed RNA polymerase subunit × 1 (A0A7M4DUC2) DNA-directed RNA polymerase subunit beta × 1 (A0A4X1TVZ5) RPOL4c domain-containing protein × 1 (A0A8D1GCS3) DNA-directed RNA polymerase II subunit E × 1 (A0A4X1VTX4) DNA-directed RNA polymerases I, II, and III subunit RPABC2 × 1 (A0A4X1VEK9) DNA-directed RNA polymerase II subunit RPB7 × 1 (A0A4X1VKG7) RPB8 × 1 RPB9 × 1 RPB10 × 1 RPB11 × 1 RNA polymerase II subunit K × 1 (A0A4X1TRS6) Transcription elongation factor SPT6 × 1 (Q7KZ85) Non-template DNA × 1 Transcription elongation factor A protein 1 × 1 (P23193) RNA × 1 RNA polymerase-associated protein CTR9 homolog × 1 (Q6PD62) RNA polymerase-associated protein RTF1 homolog × 1 (Q92541) Template DNA × 1 RNA polymerase-associated protein LEO1 × 1 (Q8WVC0) RNA polymerase II-associated factor 1 homolog × 1 (Q8N7H5) WDR61 × 1 (Q9GZS3) Parafibromin × 1 (Q6P1J9) Transcription elongation factor SPT5 × 1 (O00267) Histone H3.2 × 2 (P84233) Histone H4 × 2 (P62799) Histone H2A × 2 (Q6AZJ8) Histone H2B 1.1 × 2 (P02281) ZN ZINC ION × 8 MG MAGNESIUM ION × 1 ELECTRON MICROSCOPY cryo-EM buffer:pH 7.4 cryo-EM vitrification conditions:Cryogen ETHANE Resolution 3.00 Å

Other States of the Same Protein in the Database

Each row is a biological assembly of the same UniProt protein in another PDB entry. The “Difference from current entry” column identifies evidence-level differences; no tag means the currently parsed fields agree.

27 other PDB entries and 27 assemblies. Open the comparison page and filter oligomeric states

View Construct and Data Evidence
UniProt name A0A481DF93_PIG
Isoform
PDB entities 3
Chains and sequence ranges Author chain C; PDBConstruct 1–275; UniProt 46–320

RPOL4c domain-containing protein

OrganismNot specified

UniProt A0A8D1GCS3

State in the Current Structure

Assembly Oligomeric State Construct Mutations and Modifications Ligands, Ions and Associated Components Method and Experimental Conditions Structure Quality
1 Other combination Heteromer Protein × 29 DNA 2 RNA 1 PDB declaration: 32-meric(32) Consistent with all polymer counts Chain D; UniProt 1–184 Not recorded DNA-directed RNA polymerase subunit × 1 (A0A7M4DUC2) DNA-directed RNA polymerase subunit beta × 1 (A0A4X1TVZ5) DNA-directed RNA polymerase II subunit RPB3 × 1 (A0A481DF93) DNA-directed RNA polymerase II subunit E × 1 (A0A4X1VTX4) DNA-directed RNA polymerases I, II, and III subunit RPABC2 × 1 (A0A4X1VEK9) DNA-directed RNA polymerase II subunit RPB7 × 1 (A0A4X1VKG7) RPB8 × 1 RPB9 × 1 RPB10 × 1 RPB11 × 1 RNA polymerase II subunit K × 1 (A0A4X1TRS6) Transcription elongation factor SPT6 × 1 (Q7KZ85) Non-template DNA × 1 Transcription elongation factor A protein 1 × 1 (P23193) RNA × 1 RNA polymerase-associated protein CTR9 homolog × 1 (Q6PD62) RNA polymerase-associated protein RTF1 homolog × 1 (Q92541) Template DNA × 1 RNA polymerase-associated protein LEO1 × 1 (Q8WVC0) RNA polymerase II-associated factor 1 homolog × 1 (Q8N7H5) WDR61 × 1 (Q9GZS3) Parafibromin × 1 (Q6P1J9) Transcription elongation factor SPT5 × 1 (O00267) Histone H3.2 × 2 (P84233) Histone H4 × 2 (P62799) Histone H2A × 2 (Q6AZJ8) Histone H2B 1.1 × 2 (P02281) ZN ZINC ION × 8 MG MAGNESIUM ION × 1 ELECTRON MICROSCOPY cryo-EM buffer:pH 7.4 cryo-EM vitrification conditions:Cryogen ETHANE Resolution 3.00 Å

Other States of the Same Protein in the Database

Each row is a biological assembly of the same UniProt protein in another PDB entry. The “Difference from current entry” column identifies evidence-level differences; no tag means the currently parsed fields agree.

2 other PDB entries and 2 assemblies. Open the comparison page and filter oligomeric states

View Construct and Data Evidence
UniProt name A0A8D1GCS3_PIG
Isoform
PDB entities 4
Chains and sequence ranges Author chain D; PDBConstruct 1–184; UniProt 1–184

DNA-directed RNA polymerase II subunit E

OrganismNot specified

UniProt A0A4X1VTX4

State in the Current Structure

Assembly Oligomeric State Construct Mutations and Modifications Ligands, Ions and Associated Components Method and Experimental Conditions Structure Quality
1 Other combination Heteromer Protein × 29 DNA 2 RNA 1 PDB declaration: 32-meric(32) Consistent with all polymer counts Chain E; UniProt 1–210 Not recorded DNA-directed RNA polymerase subunit × 1 (A0A7M4DUC2) DNA-directed RNA polymerase subunit beta × 1 (A0A4X1TVZ5) DNA-directed RNA polymerase II subunit RPB3 × 1 (A0A481DF93) RPOL4c domain-containing protein × 1 (A0A8D1GCS3) DNA-directed RNA polymerases I, II, and III subunit RPABC2 × 1 (A0A4X1VEK9) DNA-directed RNA polymerase II subunit RPB7 × 1 (A0A4X1VKG7) RPB8 × 1 RPB9 × 1 RPB10 × 1 RPB11 × 1 RNA polymerase II subunit K × 1 (A0A4X1TRS6) Transcription elongation factor SPT6 × 1 (Q7KZ85) Non-template DNA × 1 Transcription elongation factor A protein 1 × 1 (P23193) RNA × 1 RNA polymerase-associated protein CTR9 homolog × 1 (Q6PD62) RNA polymerase-associated protein RTF1 homolog × 1 (Q92541) Template DNA × 1 RNA polymerase-associated protein LEO1 × 1 (Q8WVC0) RNA polymerase II-associated factor 1 homolog × 1 (Q8N7H5) WDR61 × 1 (Q9GZS3) Parafibromin × 1 (Q6P1J9) Transcription elongation factor SPT5 × 1 (O00267) Histone H3.2 × 2 (P84233) Histone H4 × 2 (P62799) Histone H2A × 2 (Q6AZJ8) Histone H2B 1.1 × 2 (P02281) ZN ZINC ION × 8 MG MAGNESIUM ION × 1 ELECTRON MICROSCOPY cryo-EM buffer:pH 7.4 cryo-EM vitrification conditions:Cryogen ETHANE Resolution 3.00 Å

Other States of the Same Protein in the Database

Each row is a biological assembly of the same UniProt protein in another PDB entry. The “Difference from current entry” column identifies evidence-level differences; no tag means the currently parsed fields agree.

46 other PDB entries and 46 assemblies. Open the comparison page and filter oligomeric states

View Construct and Data Evidence
UniProt name A0A4X1VTX4_PIG
Isoform
PDB entities 5
Chains and sequence ranges Author chain E; PDBConstruct 1–210; UniProt 1–210

DNA-directed RNA polymerases I, II, and III subunit RPABC2

OrganismNot specified

UniProt A0A4X1VEK9

State in the Current Structure

Assembly Oligomeric State Construct Mutations and Modifications Ligands, Ions and Associated Components Method and Experimental Conditions Structure Quality
1 Other combination Heteromer Protein × 29 DNA 2 RNA 1 PDB declaration: 32-meric(32) Consistent with all polymer counts Chain F; UniProt 1–127 Not recorded DNA-directed RNA polymerase subunit × 1 (A0A7M4DUC2) DNA-directed RNA polymerase subunit beta × 1 (A0A4X1TVZ5) DNA-directed RNA polymerase II subunit RPB3 × 1 (A0A481DF93) RPOL4c domain-containing protein × 1 (A0A8D1GCS3) DNA-directed RNA polymerase II subunit E × 1 (A0A4X1VTX4) DNA-directed RNA polymerase II subunit RPB7 × 1 (A0A4X1VKG7) RPB8 × 1 RPB9 × 1 RPB10 × 1 RPB11 × 1 RNA polymerase II subunit K × 1 (A0A4X1TRS6) Transcription elongation factor SPT6 × 1 (Q7KZ85) Non-template DNA × 1 Transcription elongation factor A protein 1 × 1 (P23193) RNA × 1 RNA polymerase-associated protein CTR9 homolog × 1 (Q6PD62) RNA polymerase-associated protein RTF1 homolog × 1 (Q92541) Template DNA × 1 RNA polymerase-associated protein LEO1 × 1 (Q8WVC0) RNA polymerase II-associated factor 1 homolog × 1 (Q8N7H5) WDR61 × 1 (Q9GZS3) Parafibromin × 1 (Q6P1J9) Transcription elongation factor SPT5 × 1 (O00267) Histone H3.2 × 2 (P84233) Histone H4 × 2 (P62799) Histone H2A × 2 (Q6AZJ8) Histone H2B 1.1 × 2 (P02281) ZN ZINC ION × 8 MG MAGNESIUM ION × 1 ELECTRON MICROSCOPY cryo-EM buffer:pH 7.4 cryo-EM vitrification conditions:Cryogen ETHANE Resolution 3.00 Å

Other States of the Same Protein in the Database

Each row is a biological assembly of the same UniProt protein in another PDB entry. The “Difference from current entry” column identifies evidence-level differences; no tag means the currently parsed fields agree.

57 other PDB entries and 57 assemblies. Open the comparison page and filter oligomeric states

View Construct and Data Evidence
UniProt name A0A4X1VEK9_PIG
Isoform
PDB entities 6
Chains and sequence ranges Author chain F; PDBConstruct 1–127; UniProt 1–127

DNA-directed RNA polymerase II subunit RPB7

OrganismNot specified

UniProt A0A4X1VKG7

State in the Current Structure

Assembly Oligomeric State Construct Mutations and Modifications Ligands, Ions and Associated Components Method and Experimental Conditions Structure Quality
1 Other combination Heteromer Protein × 29 DNA 2 RNA 1 PDB declaration: 32-meric(32) Consistent with all polymer counts Chain G; UniProt 1–172 Not recorded DNA-directed RNA polymerase subunit × 1 (A0A7M4DUC2) DNA-directed RNA polymerase subunit beta × 1 (A0A4X1TVZ5) DNA-directed RNA polymerase II subunit RPB3 × 1 (A0A481DF93) RPOL4c domain-containing protein × 1 (A0A8D1GCS3) DNA-directed RNA polymerase II subunit E × 1 (A0A4X1VTX4) DNA-directed RNA polymerases I, II, and III subunit RPABC2 × 1 (A0A4X1VEK9) RPB8 × 1 RPB9 × 1 RPB10 × 1 RPB11 × 1 RNA polymerase II subunit K × 1 (A0A4X1TRS6) Transcription elongation factor SPT6 × 1 (Q7KZ85) Non-template DNA × 1 Transcription elongation factor A protein 1 × 1 (P23193) RNA × 1 RNA polymerase-associated protein CTR9 homolog × 1 (Q6PD62) RNA polymerase-associated protein RTF1 homolog × 1 (Q92541) Template DNA × 1 RNA polymerase-associated protein LEO1 × 1 (Q8WVC0) RNA polymerase II-associated factor 1 homolog × 1 (Q8N7H5) WDR61 × 1 (Q9GZS3) Parafibromin × 1 (Q6P1J9) Transcription elongation factor SPT5 × 1 (O00267) Histone H3.2 × 2 (P84233) Histone H4 × 2 (P62799) Histone H2A × 2 (Q6AZJ8) Histone H2B 1.1 × 2 (P02281) ZN ZINC ION × 8 MG MAGNESIUM ION × 1 ELECTRON MICROSCOPY cryo-EM buffer:pH 7.4 cryo-EM vitrification conditions:Cryogen ETHANE Resolution 3.00 Å

Other States of the Same Protein in the Database

Each row is a biological assembly of the same UniProt protein in another PDB entry. The “Difference from current entry” column identifies evidence-level differences; no tag means the currently parsed fields agree.

83 other PDB entries and 83 assemblies. Open the comparison page and filter oligomeric states

View Construct and Data Evidence
UniProt name A0A4X1VKG7_PIG
Isoform
PDB entities 7
Chains and sequence ranges Author chain G; PDBConstruct 1–172; UniProt 1–172

RNA polymerase II subunit K

OrganismNot specified

UniProt A0A4X1TRS6

State in the Current Structure

Assembly Oligomeric State Construct Mutations and Modifications Ligands, Ions and Associated Components Method and Experimental Conditions Structure Quality
1 Other combination Heteromer Protein × 29 DNA 2 RNA 1 PDB declaration: 32-meric(32) Consistent with all polymer counts Chain L; UniProt 1–58 Not recorded DNA-directed RNA polymerase subunit × 1 (A0A7M4DUC2) DNA-directed RNA polymerase subunit beta × 1 (A0A4X1TVZ5) DNA-directed RNA polymerase II subunit RPB3 × 1 (A0A481DF93) RPOL4c domain-containing protein × 1 (A0A8D1GCS3) DNA-directed RNA polymerase II subunit E × 1 (A0A4X1VTX4) DNA-directed RNA polymerases I, II, and III subunit RPABC2 × 1 (A0A4X1VEK9) DNA-directed RNA polymerase II subunit RPB7 × 1 (A0A4X1VKG7) RPB8 × 1 RPB9 × 1 RPB10 × 1 RPB11 × 1 Transcription elongation factor SPT6 × 1 (Q7KZ85) Non-template DNA × 1 Transcription elongation factor A protein 1 × 1 (P23193) RNA × 1 RNA polymerase-associated protein CTR9 homolog × 1 (Q6PD62) RNA polymerase-associated protein RTF1 homolog × 1 (Q92541) Template DNA × 1 RNA polymerase-associated protein LEO1 × 1 (Q8WVC0) RNA polymerase II-associated factor 1 homolog × 1 (Q8N7H5) WDR61 × 1 (Q9GZS3) Parafibromin × 1 (Q6P1J9) Transcription elongation factor SPT5 × 1 (O00267) Histone H3.2 × 2 (P84233) Histone H4 × 2 (P62799) Histone H2A × 2 (Q6AZJ8) Histone H2B 1.1 × 2 (P02281) ZN ZINC ION × 8 MG MAGNESIUM ION × 1 ELECTRON MICROSCOPY cryo-EM buffer:pH 7.4 cryo-EM vitrification conditions:Cryogen ETHANE Resolution 3.00 Å

Other States of the Same Protein in the Database

Each row is a biological assembly of the same UniProt protein in another PDB entry. The “Difference from current entry” column identifies evidence-level differences; no tag means the currently parsed fields agree.

56 other PDB entries and 56 assemblies. Open the comparison page and filter oligomeric states

View Construct and Data Evidence
UniProt name A0A4X1TRS6_PIG
Isoform
PDB entities 12
Chains and sequence ranges Author chain L; PDBConstruct 1–58; UniProt 1–58

Transcription elongation factor SPT6

Homo sapiens

UniProt Q7KZ85

State in the Current Structure

Assembly Oligomeric State Construct Mutations and Modifications Ligands, Ions and Associated Components Method and Experimental Conditions Structure Quality
1 Other combination Heteromer Protein × 29 DNA 2 RNA 1 PDB declaration: 32-meric(32) Consistent with all polymer counts Chain M; UniProt 1–1726 Not recorded DNA-directed RNA polymerase subunit × 1 (A0A7M4DUC2) DNA-directed RNA polymerase subunit beta × 1 (A0A4X1TVZ5) DNA-directed RNA polymerase II subunit RPB3 × 1 (A0A481DF93) RPOL4c domain-containing protein × 1 (A0A8D1GCS3) DNA-directed RNA polymerase II subunit E × 1 (A0A4X1VTX4) DNA-directed RNA polymerases I, II, and III subunit RPABC2 × 1 (A0A4X1VEK9) DNA-directed RNA polymerase II subunit RPB7 × 1 (A0A4X1VKG7) RPB8 × 1 RPB9 × 1 RPB10 × 1 RPB11 × 1 RNA polymerase II subunit K × 1 (A0A4X1TRS6) Non-template DNA × 1 Transcription elongation factor A protein 1 × 1 (P23193) RNA × 1 RNA polymerase-associated protein CTR9 homolog × 1 (Q6PD62) RNA polymerase-associated protein RTF1 homolog × 1 (Q92541) Template DNA × 1 RNA polymerase-associated protein LEO1 × 1 (Q8WVC0) RNA polymerase II-associated factor 1 homolog × 1 (Q8N7H5) WDR61 × 1 (Q9GZS3) Parafibromin × 1 (Q6P1J9) Transcription elongation factor SPT5 × 1 (O00267) Histone H3.2 × 2 (P84233) Histone H4 × 2 (P62799) Histone H2A × 2 (Q6AZJ8) Histone H2B 1.1 × 2 (P02281) ZN ZINC ION × 8 MG MAGNESIUM ION × 1 ELECTRON MICROSCOPY cryo-EM buffer:pH 7.4 cryo-EM vitrification conditions:Cryogen ETHANE Resolution 3.00 Å

Other States of the Same Protein in the Database

Each row is a biological assembly of the same UniProt protein in another PDB entry. The “Difference from current entry” column identifies evidence-level differences; no tag means the currently parsed fields agree.

24 other PDB entries and 25 assemblies. Open the comparison page and filter oligomeric states

View Construct and Data Evidence
UniProt name SPT6H_HUMAN
Isoform
PDB entities 13
Chains and sequence ranges Author chain M; PDBConstruct 4–1729; UniProt 1–1726

Transcription elongation factor A protein 1

Homo sapiens

UniProt P23193

State in the Current Structure

Assembly Oligomeric State Construct Mutations and Modifications Ligands, Ions and Associated Components Method and Experimental Conditions Structure Quality
1 Other combination Heteromer Protein × 29 DNA 2 RNA 1 PDB declaration: 32-meric(32) Consistent with all polymer counts Chain O; UniProt 1–301 Not recorded DNA-directed RNA polymerase subunit × 1 (A0A7M4DUC2) DNA-directed RNA polymerase subunit beta × 1 (A0A4X1TVZ5) DNA-directed RNA polymerase II subunit RPB3 × 1 (A0A481DF93) RPOL4c domain-containing protein × 1 (A0A8D1GCS3) DNA-directed RNA polymerase II subunit E × 1 (A0A4X1VTX4) DNA-directed RNA polymerases I, II, and III subunit RPABC2 × 1 (A0A4X1VEK9) DNA-directed RNA polymerase II subunit RPB7 × 1 (A0A4X1VKG7) RPB8 × 1 RPB9 × 1 RPB10 × 1 RPB11 × 1 RNA polymerase II subunit K × 1 (A0A4X1TRS6) Transcription elongation factor SPT6 × 1 (Q7KZ85) Non-template DNA × 1 RNA × 1 RNA polymerase-associated protein CTR9 homolog × 1 (Q6PD62) RNA polymerase-associated protein RTF1 homolog × 1 (Q92541) Template DNA × 1 RNA polymerase-associated protein LEO1 × 1 (Q8WVC0) RNA polymerase II-associated factor 1 homolog × 1 (Q8N7H5) WDR61 × 1 (Q9GZS3) Parafibromin × 1 (Q6P1J9) Transcription elongation factor SPT5 × 1 (O00267) Histone H3.2 × 2 (P84233) Histone H4 × 2 (P62799) Histone H2A × 2 (Q6AZJ8) Histone H2B 1.1 × 2 (P02281) ZN ZINC ION × 8 MG MAGNESIUM ION × 1 ELECTRON MICROSCOPY cryo-EM buffer:pH 7.4 cryo-EM vitrification conditions:Cryogen ETHANE Resolution 3.00 Å

Other States of the Same Protein in the Database

Each row is a biological assembly of the same UniProt protein in another PDB entry. The “Difference from current entry” column identifies evidence-level differences; no tag means the currently parsed fields agree.

25 other PDB entries and 25 assemblies. Open the comparison page and filter oligomeric states

View Construct and Data Evidence
UniProt name TCEA1_HUMAN
Isoform
PDB entities 15
Chains and sequence ranges Author chain O; PDBConstruct 4–304; UniProt 1–301

RNA polymerase-associated protein CTR9 homolog

Homo sapiens

UniProt Q6PD62

State in the Current Structure

Assembly Oligomeric State Construct Mutations and Modifications Ligands, Ions and Associated Components Method and Experimental Conditions Structure Quality
1 Other combination Heteromer Protein × 29 DNA 2 RNA 1 PDB declaration: 32-meric(32) Consistent with all polymer counts Chain Q; UniProt 1–1173 Not recorded DNA-directed RNA polymerase subunit × 1 (A0A7M4DUC2) DNA-directed RNA polymerase subunit beta × 1 (A0A4X1TVZ5) DNA-directed RNA polymerase II subunit RPB3 × 1 (A0A481DF93) RPOL4c domain-containing protein × 1 (A0A8D1GCS3) DNA-directed RNA polymerase II subunit E × 1 (A0A4X1VTX4) DNA-directed RNA polymerases I, II, and III subunit RPABC2 × 1 (A0A4X1VEK9) DNA-directed RNA polymerase II subunit RPB7 × 1 (A0A4X1VKG7) RPB8 × 1 RPB9 × 1 RPB10 × 1 RPB11 × 1 RNA polymerase II subunit K × 1 (A0A4X1TRS6) Transcription elongation factor SPT6 × 1 (Q7KZ85) Non-template DNA × 1 Transcription elongation factor A protein 1 × 1 (P23193) RNA × 1 RNA polymerase-associated protein RTF1 homolog × 1 (Q92541) Template DNA × 1 RNA polymerase-associated protein LEO1 × 1 (Q8WVC0) RNA polymerase II-associated factor 1 homolog × 1 (Q8N7H5) WDR61 × 1 (Q9GZS3) Parafibromin × 1 (Q6P1J9) Transcription elongation factor SPT5 × 1 (O00267) Histone H3.2 × 2 (P84233) Histone H4 × 2 (P62799) Histone H2A × 2 (Q6AZJ8) Histone H2B 1.1 × 2 (P02281) ZN ZINC ION × 8 MG MAGNESIUM ION × 1 ELECTRON MICROSCOPY cryo-EM buffer:pH 7.4 cryo-EM vitrification conditions:Cryogen ETHANE Resolution 3.00 Å

Other States of the Same Protein in the Database

Each row is a biological assembly of the same UniProt protein in another PDB entry. The “Difference from current entry” column identifies evidence-level differences; no tag means the currently parsed fields agree.

20 other PDB entries and 20 assemblies. Open the comparison page and filter oligomeric states

View Construct and Data Evidence
UniProt name CTR9_HUMAN
Isoform
PDB entities 17
Chains and sequence ranges Author chain Q; PDBConstruct 1–1173; UniProt 1–1173

RNA polymerase-associated protein RTF1 homolog

Homo sapiens

UniProt Q92541

State in the Current Structure

Assembly Oligomeric State Construct Mutations and Modifications Ligands, Ions and Associated Components Method and Experimental Conditions Structure Quality
1 Other combination Heteromer Protein × 29 DNA 2 RNA 1 PDB declaration: 32-meric(32) Consistent with all polymer counts Chain R; UniProt 1–710 Not recorded DNA-directed RNA polymerase subunit × 1 (A0A7M4DUC2) DNA-directed RNA polymerase subunit beta × 1 (A0A4X1TVZ5) DNA-directed RNA polymerase II subunit RPB3 × 1 (A0A481DF93) RPOL4c domain-containing protein × 1 (A0A8D1GCS3) DNA-directed RNA polymerase II subunit E × 1 (A0A4X1VTX4) DNA-directed RNA polymerases I, II, and III subunit RPABC2 × 1 (A0A4X1VEK9) DNA-directed RNA polymerase II subunit RPB7 × 1 (A0A4X1VKG7) RPB8 × 1 RPB9 × 1 RPB10 × 1 RPB11 × 1 RNA polymerase II subunit K × 1 (A0A4X1TRS6) Transcription elongation factor SPT6 × 1 (Q7KZ85) Non-template DNA × 1 Transcription elongation factor A protein 1 × 1 (P23193) RNA × 1 RNA polymerase-associated protein CTR9 homolog × 1 (Q6PD62) Template DNA × 1 RNA polymerase-associated protein LEO1 × 1 (Q8WVC0) RNA polymerase II-associated factor 1 homolog × 1 (Q8N7H5) WDR61 × 1 (Q9GZS3) Parafibromin × 1 (Q6P1J9) Transcription elongation factor SPT5 × 1 (O00267) Histone H3.2 × 2 (P84233) Histone H4 × 2 (P62799) Histone H2A × 2 (Q6AZJ8) Histone H2B 1.1 × 2 (P02281) ZN ZINC ION × 8 MG MAGNESIUM ION × 1 ELECTRON MICROSCOPY cryo-EM buffer:pH 7.4 cryo-EM vitrification conditions:Cryogen ETHANE Resolution 3.00 Å

Other States of the Same Protein in the Database

Each row is a biological assembly of the same UniProt protein in another PDB entry. The “Difference from current entry” column identifies evidence-level differences; no tag means the currently parsed fields agree.

17 other PDB entries and 24 assemblies. Open the comparison page and filter oligomeric states

View Construct and Data Evidence
UniProt name RTF1_HUMAN
Isoform
PDB entities 18
Chains and sequence ranges Author chain R; PDBConstruct 4–713; UniProt 1–710

RNA polymerase-associated protein LEO1

Homo sapiens

UniProt Q8WVC0

State in the Current Structure

Assembly Oligomeric State Construct Mutations and Modifications Ligands, Ions and Associated Components Method and Experimental Conditions Structure Quality
1 Other combination Heteromer Protein × 29 DNA 2 RNA 1 PDB declaration: 32-meric(32) Consistent with all polymer counts Chain U; UniProt 1–666 Not recorded DNA-directed RNA polymerase subunit × 1 (A0A7M4DUC2) DNA-directed RNA polymerase subunit beta × 1 (A0A4X1TVZ5) DNA-directed RNA polymerase II subunit RPB3 × 1 (A0A481DF93) RPOL4c domain-containing protein × 1 (A0A8D1GCS3) DNA-directed RNA polymerase II subunit E × 1 (A0A4X1VTX4) DNA-directed RNA polymerases I, II, and III subunit RPABC2 × 1 (A0A4X1VEK9) DNA-directed RNA polymerase II subunit RPB7 × 1 (A0A4X1VKG7) RPB8 × 1 RPB9 × 1 RPB10 × 1 RPB11 × 1 RNA polymerase II subunit K × 1 (A0A4X1TRS6) Transcription elongation factor SPT6 × 1 (Q7KZ85) Non-template DNA × 1 Transcription elongation factor A protein 1 × 1 (P23193) RNA × 1 RNA polymerase-associated protein CTR9 homolog × 1 (Q6PD62) RNA polymerase-associated protein RTF1 homolog × 1 (Q92541) Template DNA × 1 RNA polymerase II-associated factor 1 homolog × 1 (Q8N7H5) WDR61 × 1 (Q9GZS3) Parafibromin × 1 (Q6P1J9) Transcription elongation factor SPT5 × 1 (O00267) Histone H3.2 × 2 (P84233) Histone H4 × 2 (P62799) Histone H2A × 2 (Q6AZJ8) Histone H2B 1.1 × 2 (P02281) ZN ZINC ION × 8 MG MAGNESIUM ION × 1 ELECTRON MICROSCOPY cryo-EM buffer:pH 7.4 cryo-EM vitrification conditions:Cryogen ETHANE Resolution 3.00 Å

Other States of the Same Protein in the Database

Each row is a biological assembly of the same UniProt protein in another PDB entry. The “Difference from current entry” column identifies evidence-level differences; no tag means the currently parsed fields agree.

19 other PDB entries and 20 assemblies. Open the comparison page and filter oligomeric states

View Construct and Data Evidence
UniProt name LEO1_HUMAN
Isoform
PDB entities 20
Chains and sequence ranges Author chain U; PDBConstruct 1–666; UniProt 1–666

RNA polymerase II-associated factor 1 homolog

Homo sapiens

UniProt Q8N7H5

State in the Current Structure

Assembly Oligomeric State Construct Mutations and Modifications Ligands, Ions and Associated Components Method and Experimental Conditions Structure Quality
1 Other combination Heteromer Protein × 29 DNA 2 RNA 1 PDB declaration: 32-meric(32) Consistent with all polymer counts Chain V; UniProt 1–531 Not recorded DNA-directed RNA polymerase subunit × 1 (A0A7M4DUC2) DNA-directed RNA polymerase subunit beta × 1 (A0A4X1TVZ5) DNA-directed RNA polymerase II subunit RPB3 × 1 (A0A481DF93) RPOL4c domain-containing protein × 1 (A0A8D1GCS3) DNA-directed RNA polymerase II subunit E × 1 (A0A4X1VTX4) DNA-directed RNA polymerases I, II, and III subunit RPABC2 × 1 (A0A4X1VEK9) DNA-directed RNA polymerase II subunit RPB7 × 1 (A0A4X1VKG7) RPB8 × 1 RPB9 × 1 RPB10 × 1 RPB11 × 1 RNA polymerase II subunit K × 1 (A0A4X1TRS6) Transcription elongation factor SPT6 × 1 (Q7KZ85) Non-template DNA × 1 Transcription elongation factor A protein 1 × 1 (P23193) RNA × 1 RNA polymerase-associated protein CTR9 homolog × 1 (Q6PD62) RNA polymerase-associated protein RTF1 homolog × 1 (Q92541) Template DNA × 1 RNA polymerase-associated protein LEO1 × 1 (Q8WVC0) WDR61 × 1 (Q9GZS3) Parafibromin × 1 (Q6P1J9) Transcription elongation factor SPT5 × 1 (O00267) Histone H3.2 × 2 (P84233) Histone H4 × 2 (P62799) Histone H2A × 2 (Q6AZJ8) Histone H2B 1.1 × 2 (P02281) ZN ZINC ION × 8 MG MAGNESIUM ION × 1 ELECTRON MICROSCOPY cryo-EM buffer:pH 7.4 cryo-EM vitrification conditions:Cryogen ETHANE Resolution 3.00 Å

Other States of the Same Protein in the Database

Each row is a biological assembly of the same UniProt protein in another PDB entry. The “Difference from current entry” column identifies evidence-level differences; no tag means the currently parsed fields agree.

20 other PDB entries and 21 assemblies. Open the comparison page and filter oligomeric states

View Construct and Data Evidence
UniProt name PAF1_HUMAN
Isoform
PDB entities 21
Chains and sequence ranges Author chain V; PDBConstruct 1–531; UniProt 1–531

WDR61

Homo sapiens

UniProt Q9GZS3

State in the Current Structure

Assembly Oligomeric State Construct Mutations and Modifications Ligands, Ions and Associated Components Method and Experimental Conditions Structure Quality
1 Other combination Heteromer Protein × 29 DNA 2 RNA 1 PDB declaration: 32-meric(32) Consistent with all polymer counts Chain W; UniProt 1–305 Not recorded DNA-directed RNA polymerase subunit × 1 (A0A7M4DUC2) DNA-directed RNA polymerase subunit beta × 1 (A0A4X1TVZ5) DNA-directed RNA polymerase II subunit RPB3 × 1 (A0A481DF93) RPOL4c domain-containing protein × 1 (A0A8D1GCS3) DNA-directed RNA polymerase II subunit E × 1 (A0A4X1VTX4) DNA-directed RNA polymerases I, II, and III subunit RPABC2 × 1 (A0A4X1VEK9) DNA-directed RNA polymerase II subunit RPB7 × 1 (A0A4X1VKG7) RPB8 × 1 RPB9 × 1 RPB10 × 1 RPB11 × 1 RNA polymerase II subunit K × 1 (A0A4X1TRS6) Transcription elongation factor SPT6 × 1 (Q7KZ85) Non-template DNA × 1 Transcription elongation factor A protein 1 × 1 (P23193) RNA × 1 RNA polymerase-associated protein CTR9 homolog × 1 (Q6PD62) RNA polymerase-associated protein RTF1 homolog × 1 (Q92541) Template DNA × 1 RNA polymerase-associated protein LEO1 × 1 (Q8WVC0) RNA polymerase II-associated factor 1 homolog × 1 (Q8N7H5) Parafibromin × 1 (Q6P1J9) Transcription elongation factor SPT5 × 1 (O00267) Histone H3.2 × 2 (P84233) Histone H4 × 2 (P62799) Histone H2A × 2 (Q6AZJ8) Histone H2B 1.1 × 2 (P02281) ZN ZINC ION × 8 MG MAGNESIUM ION × 1 ELECTRON MICROSCOPY cryo-EM buffer:pH 7.4 cryo-EM vitrification conditions:Cryogen ETHANE Resolution 3.00 Å

Other States of the Same Protein in the Database

Each row is a biological assembly of the same UniProt protein in another PDB entry. The “Difference from current entry” column identifies evidence-level differences; no tag means the currently parsed fields agree.

27 other PDB entries and 30 assemblies. Open the comparison page and filter oligomeric states

View Construct and Data Evidence
UniProt name WDR61_HUMAN
Isoform
PDB entities 22
Chains and sequence ranges Author chain W; PDBConstruct 1–305; UniProt 1–305

Parafibromin

Homo sapiens

UniProt Q6P1J9

State in the Current Structure

Assembly Oligomeric State Construct Mutations and Modifications Ligands, Ions and Associated Components Method and Experimental Conditions Structure Quality
1 Other combination Heteromer Protein × 29 DNA 2 RNA 1 PDB declaration: 32-meric(32) Consistent with all polymer counts Chain X; UniProt 1–531 Not recorded DNA-directed RNA polymerase subunit × 1 (A0A7M4DUC2) DNA-directed RNA polymerase subunit beta × 1 (A0A4X1TVZ5) DNA-directed RNA polymerase II subunit RPB3 × 1 (A0A481DF93) RPOL4c domain-containing protein × 1 (A0A8D1GCS3) DNA-directed RNA polymerase II subunit E × 1 (A0A4X1VTX4) DNA-directed RNA polymerases I, II, and III subunit RPABC2 × 1 (A0A4X1VEK9) DNA-directed RNA polymerase II subunit RPB7 × 1 (A0A4X1VKG7) RPB8 × 1 RPB9 × 1 RPB10 × 1 RPB11 × 1 RNA polymerase II subunit K × 1 (A0A4X1TRS6) Transcription elongation factor SPT6 × 1 (Q7KZ85) Non-template DNA × 1 Transcription elongation factor A protein 1 × 1 (P23193) RNA × 1 RNA polymerase-associated protein CTR9 homolog × 1 (Q6PD62) RNA polymerase-associated protein RTF1 homolog × 1 (Q92541) Template DNA × 1 RNA polymerase-associated protein LEO1 × 1 (Q8WVC0) RNA polymerase II-associated factor 1 homolog × 1 (Q8N7H5) WDR61 × 1 (Q9GZS3) Transcription elongation factor SPT5 × 1 (O00267) Histone H3.2 × 2 (P84233) Histone H4 × 2 (P62799) Histone H2A × 2 (Q6AZJ8) Histone H2B 1.1 × 2 (P02281) ZN ZINC ION × 8 MG MAGNESIUM ION × 1 ELECTRON MICROSCOPY cryo-EM buffer:pH 7.4 cryo-EM vitrification conditions:Cryogen ETHANE Resolution 3.00 Å

Other States of the Same Protein in the Database

Each row is a biological assembly of the same UniProt protein in another PDB entry. The “Difference from current entry” column identifies evidence-level differences; no tag means the currently parsed fields agree.

20 other PDB entries and 21 assemblies. Open the comparison page and filter oligomeric states

View Construct and Data Evidence
UniProt name CDC73_HUMAN
Isoform
PDB entities 23
Chains and sequence ranges Author chain X; PDBConstruct 1–531; UniProt 1–531

Transcription elongation factor SPT5

Homo sapiens

UniProt O00267

State in the Current Structure

Assembly Oligomeric State Construct Mutations and Modifications Ligands, Ions and Associated Components Method and Experimental Conditions Structure Quality
1 Other combination Heteromer Protein × 29 DNA 2 RNA 1 PDB declaration: 32-meric(32) Consistent with all polymer counts Chain Z; UniProt 1–1087 Non-standard monomer:Yes (specific site not provided by mmCIF) DNA-directed RNA polymerase subunit × 1 (A0A7M4DUC2) DNA-directed RNA polymerase subunit beta × 1 (A0A4X1TVZ5) DNA-directed RNA polymerase II subunit RPB3 × 1 (A0A481DF93) RPOL4c domain-containing protein × 1 (A0A8D1GCS3) DNA-directed RNA polymerase II subunit E × 1 (A0A4X1VTX4) DNA-directed RNA polymerases I, II, and III subunit RPABC2 × 1 (A0A4X1VEK9) DNA-directed RNA polymerase II subunit RPB7 × 1 (A0A4X1VKG7) RPB8 × 1 RPB9 × 1 RPB10 × 1 RPB11 × 1 RNA polymerase II subunit K × 1 (A0A4X1TRS6) Transcription elongation factor SPT6 × 1 (Q7KZ85) Non-template DNA × 1 Transcription elongation factor A protein 1 × 1 (P23193) RNA × 1 RNA polymerase-associated protein CTR9 homolog × 1 (Q6PD62) RNA polymerase-associated protein RTF1 homolog × 1 (Q92541) Template DNA × 1 RNA polymerase-associated protein LEO1 × 1 (Q8WVC0) RNA polymerase II-associated factor 1 homolog × 1 (Q8N7H5) WDR61 × 1 (Q9GZS3) Parafibromin × 1 (Q6P1J9) Histone H3.2 × 2 (P84233) Histone H4 × 2 (P62799) Histone H2A × 2 (Q6AZJ8) Histone H2B 1.1 × 2 (P02281) ZN ZINC ION × 8 MG MAGNESIUM ION × 1 ELECTRON MICROSCOPY cryo-EM buffer:pH 7.4 cryo-EM vitrification conditions:Cryogen ETHANE Resolution 3.00 Å

Other States of the Same Protein in the Database

Each row is a biological assembly of the same UniProt protein in another PDB entry. The “Difference from current entry” column identifies evidence-level differences; no tag means the currently parsed fields agree.

53 other PDB entries and 57 assemblies. Open the comparison page and filter oligomeric states

View Construct and Data Evidence
UniProt name SPT5H_HUMAN
Isoform
PDB entities 24
Chains and sequence ranges Author chain Z; PDBConstruct 1–1087; UniProt 1–1087

Histone H3.2

Xenopus laevis

UniProt P84233

State in the Current Structure

Assembly Oligomeric State Construct Mutations and Modifications Ligands, Ions and Associated Components Method and Experimental Conditions Structure Quality
1 Other combination Heteromer Protein × 29 DNA 2 RNA 1 PDB declaration: 32-meric(32) Consistent with all polymer counts Chain a; UniProt 1–136 Chain e; UniProt 1–136 Mutation:G102A DNA-directed RNA polymerase subunit × 1 (A0A7M4DUC2) DNA-directed RNA polymerase subunit beta × 1 (A0A4X1TVZ5) DNA-directed RNA polymerase II subunit RPB3 × 1 (A0A481DF93) RPOL4c domain-containing protein × 1 (A0A8D1GCS3) DNA-directed RNA polymerase II subunit E × 1 (A0A4X1VTX4) DNA-directed RNA polymerases I, II, and III subunit RPABC2 × 1 (A0A4X1VEK9) DNA-directed RNA polymerase II subunit RPB7 × 1 (A0A4X1VKG7) RPB8 × 1 RPB9 × 1 RPB10 × 1 RPB11 × 1 RNA polymerase II subunit K × 1 (A0A4X1TRS6) Transcription elongation factor SPT6 × 1 (Q7KZ85) Non-template DNA × 1 Transcription elongation factor A protein 1 × 1 (P23193) RNA × 1 RNA polymerase-associated protein CTR9 homolog × 1 (Q6PD62) RNA polymerase-associated protein RTF1 homolog × 1 (Q92541) Template DNA × 1 RNA polymerase-associated protein LEO1 × 1 (Q8WVC0) RNA polymerase II-associated factor 1 homolog × 1 (Q8N7H5) WDR61 × 1 (Q9GZS3) Parafibromin × 1 (Q6P1J9) Transcription elongation factor SPT5 × 1 (O00267) Histone H4 × 2 (P62799) Histone H2A × 2 (Q6AZJ8) Histone H2B 1.1 × 2 (P02281) ZN ZINC ION × 8 MG MAGNESIUM ION × 1 ELECTRON MICROSCOPY cryo-EM buffer:pH 7.4 cryo-EM vitrification conditions:Cryogen ETHANE Resolution 3.00 Å

Other States of the Same Protein in the Database

Each row is a biological assembly of the same UniProt protein in another PDB entry. The “Difference from current entry” column identifies evidence-level differences; no tag means the currently parsed fields agree.

230 other PDB entries and 239 assemblies. Open the comparison page and filter oligomeric states

View Construct and Data Evidence
UniProt name H32_XENLA
Isoform
PDB entities 25
Chains and sequence ranges Author chain a; PDBConstruct 1–136; UniProt 1–136 Author chain e; PDBConstruct 1–136; UniProt 1–136

Histone H4

Xenopus laevis

UniProt P62799

State in the Current Structure

Assembly Oligomeric State Construct Mutations and Modifications Ligands, Ions and Associated Components Method and Experimental Conditions Structure Quality
1 Other combination Heteromer Protein × 29 DNA 2 RNA 1 PDB declaration: 32-meric(32) Consistent with all polymer counts Chain b; UniProt 1–103 Chain f; UniProt 1–103 Not recorded DNA-directed RNA polymerase subunit × 1 (A0A7M4DUC2) DNA-directed RNA polymerase subunit beta × 1 (A0A4X1TVZ5) DNA-directed RNA polymerase II subunit RPB3 × 1 (A0A481DF93) RPOL4c domain-containing protein × 1 (A0A8D1GCS3) DNA-directed RNA polymerase II subunit E × 1 (A0A4X1VTX4) DNA-directed RNA polymerases I, II, and III subunit RPABC2 × 1 (A0A4X1VEK9) DNA-directed RNA polymerase II subunit RPB7 × 1 (A0A4X1VKG7) RPB8 × 1 RPB9 × 1 RPB10 × 1 RPB11 × 1 RNA polymerase II subunit K × 1 (A0A4X1TRS6) Transcription elongation factor SPT6 × 1 (Q7KZ85) Non-template DNA × 1 Transcription elongation factor A protein 1 × 1 (P23193) RNA × 1 RNA polymerase-associated protein CTR9 homolog × 1 (Q6PD62) RNA polymerase-associated protein RTF1 homolog × 1 (Q92541) Template DNA × 1 RNA polymerase-associated protein LEO1 × 1 (Q8WVC0) RNA polymerase II-associated factor 1 homolog × 1 (Q8N7H5) WDR61 × 1 (Q9GZS3) Parafibromin × 1 (Q6P1J9) Transcription elongation factor SPT5 × 1 (O00267) Histone H3.2 × 2 (P84233) Histone H2A × 2 (Q6AZJ8) Histone H2B 1.1 × 2 (P02281) ZN ZINC ION × 8 MG MAGNESIUM ION × 1 ELECTRON MICROSCOPY cryo-EM buffer:pH 7.4 cryo-EM vitrification conditions:Cryogen ETHANE Resolution 3.00 Å

Other States of the Same Protein in the Database

Each row is a biological assembly of the same UniProt protein in another PDB entry. The “Difference from current entry” column identifies evidence-level differences; no tag means the currently parsed fields agree.

354 other PDB entries and 370 assemblies. Open the comparison page and filter oligomeric states

View Construct and Data Evidence
UniProt name H4_XENLA
Isoform
PDB entities 26
Chains and sequence ranges Author chain b; PDBConstruct 1–103; UniProt 1–103 Author chain f; PDBConstruct 1–103; UniProt 1–103

Histone H2A

Xenopus laevis

UniProt Q6AZJ8

State in the Current Structure

Assembly Oligomeric State Construct Mutations and Modifications Ligands, Ions and Associated Components Method and Experimental Conditions Structure Quality
1 Other combination Heteromer Protein × 29 DNA 2 RNA 1 PDB declaration: 32-meric(32) Consistent with all polymer counts Chain c; UniProt 1–130 Chain g; UniProt 1–130 Not recorded DNA-directed RNA polymerase subunit × 1 (A0A7M4DUC2) DNA-directed RNA polymerase subunit beta × 1 (A0A4X1TVZ5) DNA-directed RNA polymerase II subunit RPB3 × 1 (A0A481DF93) RPOL4c domain-containing protein × 1 (A0A8D1GCS3) DNA-directed RNA polymerase II subunit E × 1 (A0A4X1VTX4) DNA-directed RNA polymerases I, II, and III subunit RPABC2 × 1 (A0A4X1VEK9) DNA-directed RNA polymerase II subunit RPB7 × 1 (A0A4X1VKG7) RPB8 × 1 RPB9 × 1 RPB10 × 1 RPB11 × 1 RNA polymerase II subunit K × 1 (A0A4X1TRS6) Transcription elongation factor SPT6 × 1 (Q7KZ85) Non-template DNA × 1 Transcription elongation factor A protein 1 × 1 (P23193) RNA × 1 RNA polymerase-associated protein CTR9 homolog × 1 (Q6PD62) RNA polymerase-associated protein RTF1 homolog × 1 (Q92541) Template DNA × 1 RNA polymerase-associated protein LEO1 × 1 (Q8WVC0) RNA polymerase II-associated factor 1 homolog × 1 (Q8N7H5) WDR61 × 1 (Q9GZS3) Parafibromin × 1 (Q6P1J9) Transcription elongation factor SPT5 × 1 (O00267) Histone H3.2 × 2 (P84233) Histone H4 × 2 (P62799) Histone H2B 1.1 × 2 (P02281) ZN ZINC ION × 8 MG MAGNESIUM ION × 1 ELECTRON MICROSCOPY cryo-EM buffer:pH 7.4 cryo-EM vitrification conditions:Cryogen ETHANE Resolution 3.00 Å

Other States of the Same Protein in the Database

Each row is a biological assembly of the same UniProt protein in another PDB entry. The “Difference from current entry” column identifies evidence-level differences; no tag means the currently parsed fields agree.

226 other PDB entries and 238 assemblies. Open the comparison page and filter oligomeric states

View Construct and Data Evidence
UniProt name Q6AZJ8_XENLA
Isoform
PDB entities 27
Chains and sequence ranges Author chain c; PDBConstruct 1–130; UniProt 1–130 Author chain g; PDBConstruct 1–130; UniProt 1–130

Histone H2B 1.1

Xenopus laevis

UniProt P02281

State in the Current Structure

Assembly Oligomeric State Construct Mutations and Modifications Ligands, Ions and Associated Components Method and Experimental Conditions Structure Quality
1 Other combination Heteromer Protein × 29 DNA 2 RNA 1 PDB declaration: 32-meric(32) Consistent with all polymer counts Chain d; UniProt 5–126 Chain h; UniProt 5–126 Mutation:S29T DNA-directed RNA polymerase subunit × 1 (A0A7M4DUC2) DNA-directed RNA polymerase subunit beta × 1 (A0A4X1TVZ5) DNA-directed RNA polymerase II subunit RPB3 × 1 (A0A481DF93) RPOL4c domain-containing protein × 1 (A0A8D1GCS3) DNA-directed RNA polymerase II subunit E × 1 (A0A4X1VTX4) DNA-directed RNA polymerases I, II, and III subunit RPABC2 × 1 (A0A4X1VEK9) DNA-directed RNA polymerase II subunit RPB7 × 1 (A0A4X1VKG7) RPB8 × 1 RPB9 × 1 RPB10 × 1 RPB11 × 1 RNA polymerase II subunit K × 1 (A0A4X1TRS6) Transcription elongation factor SPT6 × 1 (Q7KZ85) Non-template DNA × 1 Transcription elongation factor A protein 1 × 1 (P23193) RNA × 1 RNA polymerase-associated protein CTR9 homolog × 1 (Q6PD62) RNA polymerase-associated protein RTF1 homolog × 1 (Q92541) Template DNA × 1 RNA polymerase-associated protein LEO1 × 1 (Q8WVC0) RNA polymerase II-associated factor 1 homolog × 1 (Q8N7H5) WDR61 × 1 (Q9GZS3) Parafibromin × 1 (Q6P1J9) Transcription elongation factor SPT5 × 1 (O00267) Histone H3.2 × 2 (P84233) Histone H4 × 2 (P62799) Histone H2A × 2 (Q6AZJ8) ZN ZINC ION × 8 MG MAGNESIUM ION × 1 ELECTRON MICROSCOPY cryo-EM buffer:pH 7.4 cryo-EM vitrification conditions:Cryogen ETHANE Resolution 3.00 Å

Other States of the Same Protein in the Database

Each row is a biological assembly of the same UniProt protein in another PDB entry. The “Difference from current entry” column identifies evidence-level differences; no tag means the currently parsed fields agree.

310 other PDB entries and 327 assemblies. Open the comparison page and filter oligomeric states

View Construct and Data Evidence
UniProt name H2B11_XENLA
Isoform
PDB entities 28
Chains and sequence ranges Author chain d; PDBConstruct 2–123; UniProt 5–126 Author chain h; PDBConstruct 2–123; UniProt 5–126

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

SAXS scattering curve SAXS Profile

SAXS profile for 7unc

P(r) Distance Distribution P(r) Distribution

P(r) distribution for 7unc
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2. Structure Basics 2. Structure Basics

Entry ID entry_id7unc
Deposition date deposition_date2022-04-10
Structure title titlePol II-DSIF-SPT6-PAF1c-TFIIS complex with rewrapped nucleosome
Keywords keywordsChromatin, nucleosome, transcription, intermediate; TRANSCRIPTION
Experimental Method methodELECTRON MICROSCOPY

3. SAXS Parameters (CRYSOL theoretical calculation) 3. SAXS Parameters (CRYSOL)

Radius of gyration Rg (Guinier) rg_guinier77.94
Radius of gyration Rg (electron density) rg_electron73.55
Forward intensity I(0) i013797100000.00
Molecular weight molecular_weight823980.0 kDa
Excluded volume excluded_volume958760 ų
Envelope volume envelope_volume1805700 ų
Hydration-shell volume shell_volume198400 ų
Envelope diameter envelope_diameter276.0
Shell Rg shell_rg74.13
Envelope Rg envelope_rg75.48
Shape Rg shape_rg73.79
Total Rg total_rg72.90
Total atoms total_atoms105742
Residues n_residues8232
Spherical-harmonic order n_harmonics20
q range q_range— – 0.5000 −1
Data points n_points101
Shell type shell_typedirectional
Solvent electron density solvent_density0.3340 e/ų
Shell contrast contrast_shell0.0300 e/ų
CRYSOL version crysol_version4.1.3

4. P(r) Distance Distribution (GNOM inversion) 4. P(r) Analysis (GNOM)

Maximum dimension Dmax dmax268.5
Rg (real space) rg_real80.91
Rg uncertainty (real space) rg_real_error1.64
I(0) (real space) i0_real1.3800e+10
I(0) uncertainty (real space) i0_real_error3.0320e+08
Rg (reciprocal space) rg_reciprocal77.65
I(0) (reciprocal space) i0_reciprocal13790000000.0000
Solution quality estimate total_estimate0.8845
Solution quality rating solution_quality GOOD a GOOD solution
P(r) peaks n_peaks1
Primary peak position r_peak_primary94.0
Skewness Skewness skewness0.462
Kurtosis Kurtosis kurtosis-0.178
Angular range angular_range— – 0.1000 −1
Current regularization parameter α current_alpha1.1290
Highest regularization parameter α highest_alpha1105000000.0000
Real-space data points n_real_points21
GNOM version gnom_version4.1.3
Quality Criteria quality_criteria AN1: 0.000; Oscil: 0.890; Stabil: 0.894; Sysdev: 1.000; Positv: 1.000; Valcen: 0.988; Smooth: 0.266

5. Crystallography and Experiment 5. Crystallography & Experiment

6. Entities and Polymers Entities & Polymers (30)

8. Citations (1)

9. Files and Curves (10)