8wal

Structure of transcribing complex 3 (TC3), the initially transcribing complex with Pol II positioned 3nt downstream of TSS.

Method: ELECTRON MICROSCOPY
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1. Protein Identity and Related Structures Protein Identity & Related Structures

CDK-activating kinase assembly factor MAT1

Homo sapiens

UniProt P51948

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Other combination Heteromer Protein 48 DNA 2 RNA 1 General transcription factor IIH subunit 1 × 1 (P32780) General transcription factor IIH subunit 2 × 1 (Q13888) General transcription factor IIH subunit 3 × 1 (Q13889) General transcription factor IIH subunit 4 × 1 (Q92759) General transcription factor IIH subunit 5 × 1 (Q6ZYL4) General transcription and DNA repair factor IIH helicase subunit XPB × 1 (P19447) General transcription and DNA repair factor IIH helicase subunit XPD × 1 (P18074) Alpha-amanitin × 1 (P85421) RNA × 1 Transcription initiation factor TFIID subunit 1 × 1 (P21675) Transcription initiation factor TFIID subunit 2 × 1 (Q6P1X5) Transcription initiation factor TFIID subunit 4 × 2 (O00268) Transcription initiation factor TFIID subunit 5 × 2 (Q15542) Transcription initiation factor TFIID subunit 6 × 2 (P49848) Transcription initiation factor TFIID subunit 7 × 1 (Q15545) Transcription initiation factor TFIID subunit 8 × 1 (Q7Z7C8) Transcription initiation factor TFIID subunit 9 × 2 (Q16594) Transcription initiation factor TFIID subunit 10 × 2 (Q12962) Transcription initiation factor TFIID subunit 12 × 2 (Q16514) Transcription initiation factor IIA subunit 2 × 1 (P52657) TATA-box-binding protein × 1 (P20226) Transcription initiation factor IIA beta chain × 1 (P52655) Transcription initiation factor IIB × 1 (Q00403) General transcription factor IIF subunit 1 × 1 (P35269) General transcription factor IIF subunit 2 × 1 (P13984) General transcription factor IIE subunit 1 × 1 (P29083) Transcription initiation factor IIE subunit beta × 1 (P29084) non-template DNA × 1 template DNA × 1 Transcription initiation factor TFIID subunit 3 × 1 (Q5VWG9) Transcription initiation factor TFIID subunit 11 × 1 (Q15544) Transcription initiation factor TFIID subunit 13 × 1 (Q15543) DNA-directed RNA polymerase subunit × 1 (A0A8D1DPV6) DNA-directed RNA polymerase subunit beta × 1 (A0A4X1TVZ5) DNA-directed RNA polymerase II subunit RPB3 × 1 (I3LCH3) DNA-directed RNA polymerase II subunit RPB4 × 1 (A0A481BYI6) DNA-directed RNA polymerase II subunit E × 1 (A0A4X1VTX4) DNA-directed RNA polymerase II subunit F × 1 (A0A4X1VEK9) DNA-directed RNA polymerase II subunit RPB7 × 1 (A0A4X1VKG7) DNA-directed RNA polymerases I, II, and III subunit RPABC3 × 1 (I3LCB2) DNA-directed RNA polymerase II subunit RPB9 × 1 (P60899) DNA-directed RNA polymerases I, II, and III subunit RPABC5 × 1 (A0A493TD97) DNA-directed RNA polymerase II subunit RPB11-a × 1 (F1RKE4) RPB12 × 1 (A0A4X1TRS6) ZINC ION × 17 IRON/SULFUR CLUSTER × 1 ;[[(2~{S},3~{R},4~{S},5~{R})-5-(2-azanyl-6-oxidanylidene-3~{H}-purin-9-yl)-3-methoxy-4-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate ; × 1 MAGNESIUM ION × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name MAT1_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain 0; PDBConstruct 1–309; UniProt 1–309

General transcription factor IIH subunit 1

Homo sapiens

UniProt P32780

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Other combination Heteromer Protein 48 DNA 2 RNA 1 CDK-activating kinase assembly factor MAT1 × 1 (P51948) General transcription factor IIH subunit 2 × 1 (Q13888) General transcription factor IIH subunit 3 × 1 (Q13889) General transcription factor IIH subunit 4 × 1 (Q92759) General transcription factor IIH subunit 5 × 1 (Q6ZYL4) General transcription and DNA repair factor IIH helicase subunit XPB × 1 (P19447) General transcription and DNA repair factor IIH helicase subunit XPD × 1 (P18074) Alpha-amanitin × 1 (P85421) RNA × 1 Transcription initiation factor TFIID subunit 1 × 1 (P21675) Transcription initiation factor TFIID subunit 2 × 1 (Q6P1X5) Transcription initiation factor TFIID subunit 4 × 2 (O00268) Transcription initiation factor TFIID subunit 5 × 2 (Q15542) Transcription initiation factor TFIID subunit 6 × 2 (P49848) Transcription initiation factor TFIID subunit 7 × 1 (Q15545) Transcription initiation factor TFIID subunit 8 × 1 (Q7Z7C8) Transcription initiation factor TFIID subunit 9 × 2 (Q16594) Transcription initiation factor TFIID subunit 10 × 2 (Q12962) Transcription initiation factor TFIID subunit 12 × 2 (Q16514) Transcription initiation factor IIA subunit 2 × 1 (P52657) TATA-box-binding protein × 1 (P20226) Transcription initiation factor IIA beta chain × 1 (P52655) Transcription initiation factor IIB × 1 (Q00403) General transcription factor IIF subunit 1 × 1 (P35269) General transcription factor IIF subunit 2 × 1 (P13984) General transcription factor IIE subunit 1 × 1 (P29083) Transcription initiation factor IIE subunit beta × 1 (P29084) non-template DNA × 1 template DNA × 1 Transcription initiation factor TFIID subunit 3 × 1 (Q5VWG9) Transcription initiation factor TFIID subunit 11 × 1 (Q15544) Transcription initiation factor TFIID subunit 13 × 1 (Q15543) DNA-directed RNA polymerase subunit × 1 (A0A8D1DPV6) DNA-directed RNA polymerase subunit beta × 1 (A0A4X1TVZ5) DNA-directed RNA polymerase II subunit RPB3 × 1 (I3LCH3) DNA-directed RNA polymerase II subunit RPB4 × 1 (A0A481BYI6) DNA-directed RNA polymerase II subunit E × 1 (A0A4X1VTX4) DNA-directed RNA polymerase II subunit F × 1 (A0A4X1VEK9) DNA-directed RNA polymerase II subunit RPB7 × 1 (A0A4X1VKG7) DNA-directed RNA polymerases I, II, and III subunit RPABC3 × 1 (I3LCB2) DNA-directed RNA polymerase II subunit RPB9 × 1 (P60899) DNA-directed RNA polymerases I, II, and III subunit RPABC5 × 1 (A0A493TD97) DNA-directed RNA polymerase II subunit RPB11-a × 1 (F1RKE4) RPB12 × 1 (A0A4X1TRS6) ZINC ION × 17 IRON/SULFUR CLUSTER × 1 ;[[(2~{S},3~{R},4~{S},5~{R})-5-(2-azanyl-6-oxidanylidene-3~{H}-purin-9-yl)-3-methoxy-4-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate ; × 1 MAGNESIUM ION × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name TF2H1_HUMAN
Isoform —
PDB entities 2
Chains and sequence ranges Author chain 1; PDBConstruct 1–548; UniProt 1–548

General transcription factor IIH subunit 2

Homo sapiens

UniProt Q13888

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Other combination Heteromer Protein 48 DNA 2 RNA 1 CDK-activating kinase assembly factor MAT1 × 1 (P51948) General transcription factor IIH subunit 1 × 1 (P32780) General transcription factor IIH subunit 3 × 1 (Q13889) General transcription factor IIH subunit 4 × 1 (Q92759) General transcription factor IIH subunit 5 × 1 (Q6ZYL4) General transcription and DNA repair factor IIH helicase subunit XPB × 1 (P19447) General transcription and DNA repair factor IIH helicase subunit XPD × 1 (P18074) Alpha-amanitin × 1 (P85421) RNA × 1 Transcription initiation factor TFIID subunit 1 × 1 (P21675) Transcription initiation factor TFIID subunit 2 × 1 (Q6P1X5) Transcription initiation factor TFIID subunit 4 × 2 (O00268) Transcription initiation factor TFIID subunit 5 × 2 (Q15542) Transcription initiation factor TFIID subunit 6 × 2 (P49848) Transcription initiation factor TFIID subunit 7 × 1 (Q15545) Transcription initiation factor TFIID subunit 8 × 1 (Q7Z7C8) Transcription initiation factor TFIID subunit 9 × 2 (Q16594) Transcription initiation factor TFIID subunit 10 × 2 (Q12962) Transcription initiation factor TFIID subunit 12 × 2 (Q16514) Transcription initiation factor IIA subunit 2 × 1 (P52657) TATA-box-binding protein × 1 (P20226) Transcription initiation factor IIA beta chain × 1 (P52655) Transcription initiation factor IIB × 1 (Q00403) General transcription factor IIF subunit 1 × 1 (P35269) General transcription factor IIF subunit 2 × 1 (P13984) General transcription factor IIE subunit 1 × 1 (P29083) Transcription initiation factor IIE subunit beta × 1 (P29084) non-template DNA × 1 template DNA × 1 Transcription initiation factor TFIID subunit 3 × 1 (Q5VWG9) Transcription initiation factor TFIID subunit 11 × 1 (Q15544) Transcription initiation factor TFIID subunit 13 × 1 (Q15543) DNA-directed RNA polymerase subunit × 1 (A0A8D1DPV6) DNA-directed RNA polymerase subunit beta × 1 (A0A4X1TVZ5) DNA-directed RNA polymerase II subunit RPB3 × 1 (I3LCH3) DNA-directed RNA polymerase II subunit RPB4 × 1 (A0A481BYI6) DNA-directed RNA polymerase II subunit E × 1 (A0A4X1VTX4) DNA-directed RNA polymerase II subunit F × 1 (A0A4X1VEK9) DNA-directed RNA polymerase II subunit RPB7 × 1 (A0A4X1VKG7) DNA-directed RNA polymerases I, II, and III subunit RPABC3 × 1 (I3LCB2) DNA-directed RNA polymerase II subunit RPB9 × 1 (P60899) DNA-directed RNA polymerases I, II, and III subunit RPABC5 × 1 (A0A493TD97) DNA-directed RNA polymerase II subunit RPB11-a × 1 (F1RKE4) RPB12 × 1 (A0A4X1TRS6) ZINC ION × 17 IRON/SULFUR CLUSTER × 1 ;[[(2~{S},3~{R},4~{S},5~{R})-5-(2-azanyl-6-oxidanylidene-3~{H}-purin-9-yl)-3-methoxy-4-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate ; × 1 MAGNESIUM ION × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name TF2H2_HUMAN
Isoform —
PDB entities 3
Chains and sequence ranges Author chain 2; PDBConstruct 1–395; UniProt 1–395

General transcription factor IIH subunit 3

Homo sapiens

UniProt Q13889

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Other combination Heteromer Protein 48 DNA 2 RNA 1 CDK-activating kinase assembly factor MAT1 × 1 (P51948) General transcription factor IIH subunit 1 × 1 (P32780) General transcription factor IIH subunit 2 × 1 (Q13888) General transcription factor IIH subunit 4 × 1 (Q92759) General transcription factor IIH subunit 5 × 1 (Q6ZYL4) General transcription and DNA repair factor IIH helicase subunit XPB × 1 (P19447) General transcription and DNA repair factor IIH helicase subunit XPD × 1 (P18074) Alpha-amanitin × 1 (P85421) RNA × 1 Transcription initiation factor TFIID subunit 1 × 1 (P21675) Transcription initiation factor TFIID subunit 2 × 1 (Q6P1X5) Transcription initiation factor TFIID subunit 4 × 2 (O00268) Transcription initiation factor TFIID subunit 5 × 2 (Q15542) Transcription initiation factor TFIID subunit 6 × 2 (P49848) Transcription initiation factor TFIID subunit 7 × 1 (Q15545) Transcription initiation factor TFIID subunit 8 × 1 (Q7Z7C8) Transcription initiation factor TFIID subunit 9 × 2 (Q16594) Transcription initiation factor TFIID subunit 10 × 2 (Q12962) Transcription initiation factor TFIID subunit 12 × 2 (Q16514) Transcription initiation factor IIA subunit 2 × 1 (P52657) TATA-box-binding protein × 1 (P20226) Transcription initiation factor IIA beta chain × 1 (P52655) Transcription initiation factor IIB × 1 (Q00403) General transcription factor IIF subunit 1 × 1 (P35269) General transcription factor IIF subunit 2 × 1 (P13984) General transcription factor IIE subunit 1 × 1 (P29083) Transcription initiation factor IIE subunit beta × 1 (P29084) non-template DNA × 1 template DNA × 1 Transcription initiation factor TFIID subunit 3 × 1 (Q5VWG9) Transcription initiation factor TFIID subunit 11 × 1 (Q15544) Transcription initiation factor TFIID subunit 13 × 1 (Q15543) DNA-directed RNA polymerase subunit × 1 (A0A8D1DPV6) DNA-directed RNA polymerase subunit beta × 1 (A0A4X1TVZ5) DNA-directed RNA polymerase II subunit RPB3 × 1 (I3LCH3) DNA-directed RNA polymerase II subunit RPB4 × 1 (A0A481BYI6) DNA-directed RNA polymerase II subunit E × 1 (A0A4X1VTX4) DNA-directed RNA polymerase II subunit F × 1 (A0A4X1VEK9) DNA-directed RNA polymerase II subunit RPB7 × 1 (A0A4X1VKG7) DNA-directed RNA polymerases I, II, and III subunit RPABC3 × 1 (I3LCB2) DNA-directed RNA polymerase II subunit RPB9 × 1 (P60899) DNA-directed RNA polymerases I, II, and III subunit RPABC5 × 1 (A0A493TD97) DNA-directed RNA polymerase II subunit RPB11-a × 1 (F1RKE4) RPB12 × 1 (A0A4X1TRS6) ZINC ION × 17 IRON/SULFUR CLUSTER × 1 ;[[(2~{S},3~{R},4~{S},5~{R})-5-(2-azanyl-6-oxidanylidene-3~{H}-purin-9-yl)-3-methoxy-4-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate ; × 1 MAGNESIUM ION × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name TF2H3_HUMAN
Isoform —
PDB entities 4
Chains and sequence ranges Author chain 3; PDBConstruct 1–308; UniProt 1–308

General transcription factor IIH subunit 4

Homo sapiens

UniProt Q92759

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Other combination Heteromer Protein 48 DNA 2 RNA 1 CDK-activating kinase assembly factor MAT1 × 1 (P51948) General transcription factor IIH subunit 1 × 1 (P32780) General transcription factor IIH subunit 2 × 1 (Q13888) General transcription factor IIH subunit 3 × 1 (Q13889) General transcription factor IIH subunit 5 × 1 (Q6ZYL4) General transcription and DNA repair factor IIH helicase subunit XPB × 1 (P19447) General transcription and DNA repair factor IIH helicase subunit XPD × 1 (P18074) Alpha-amanitin × 1 (P85421) RNA × 1 Transcription initiation factor TFIID subunit 1 × 1 (P21675) Transcription initiation factor TFIID subunit 2 × 1 (Q6P1X5) Transcription initiation factor TFIID subunit 4 × 2 (O00268) Transcription initiation factor TFIID subunit 5 × 2 (Q15542) Transcription initiation factor TFIID subunit 6 × 2 (P49848) Transcription initiation factor TFIID subunit 7 × 1 (Q15545) Transcription initiation factor TFIID subunit 8 × 1 (Q7Z7C8) Transcription initiation factor TFIID subunit 9 × 2 (Q16594) Transcription initiation factor TFIID subunit 10 × 2 (Q12962) Transcription initiation factor TFIID subunit 12 × 2 (Q16514) Transcription initiation factor IIA subunit 2 × 1 (P52657) TATA-box-binding protein × 1 (P20226) Transcription initiation factor IIA beta chain × 1 (P52655) Transcription initiation factor IIB × 1 (Q00403) General transcription factor IIF subunit 1 × 1 (P35269) General transcription factor IIF subunit 2 × 1 (P13984) General transcription factor IIE subunit 1 × 1 (P29083) Transcription initiation factor IIE subunit beta × 1 (P29084) non-template DNA × 1 template DNA × 1 Transcription initiation factor TFIID subunit 3 × 1 (Q5VWG9) Transcription initiation factor TFIID subunit 11 × 1 (Q15544) Transcription initiation factor TFIID subunit 13 × 1 (Q15543) DNA-directed RNA polymerase subunit × 1 (A0A8D1DPV6) DNA-directed RNA polymerase subunit beta × 1 (A0A4X1TVZ5) DNA-directed RNA polymerase II subunit RPB3 × 1 (I3LCH3) DNA-directed RNA polymerase II subunit RPB4 × 1 (A0A481BYI6) DNA-directed RNA polymerase II subunit E × 1 (A0A4X1VTX4) DNA-directed RNA polymerase II subunit F × 1 (A0A4X1VEK9) DNA-directed RNA polymerase II subunit RPB7 × 1 (A0A4X1VKG7) DNA-directed RNA polymerases I, II, and III subunit RPABC3 × 1 (I3LCB2) DNA-directed RNA polymerase II subunit RPB9 × 1 (P60899) DNA-directed RNA polymerases I, II, and III subunit RPABC5 × 1 (A0A493TD97) DNA-directed RNA polymerase II subunit RPB11-a × 1 (F1RKE4) RPB12 × 1 (A0A4X1TRS6) ZINC ION × 17 IRON/SULFUR CLUSTER × 1 ;[[(2~{S},3~{R},4~{S},5~{R})-5-(2-azanyl-6-oxidanylidene-3~{H}-purin-9-yl)-3-methoxy-4-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate ; × 1 MAGNESIUM ION × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name TF2H4_HUMAN
Isoform —
PDB entities 5
Chains and sequence ranges Author chain 4; PDBConstruct 1–462; UniProt 1–462

General transcription factor IIH subunit 5

Homo sapiens

UniProt Q6ZYL4

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Other combination Heteromer Protein 48 DNA 2 RNA 1 CDK-activating kinase assembly factor MAT1 × 1 (P51948) General transcription factor IIH subunit 1 × 1 (P32780) General transcription factor IIH subunit 2 × 1 (Q13888) General transcription factor IIH subunit 3 × 1 (Q13889) General transcription factor IIH subunit 4 × 1 (Q92759) General transcription and DNA repair factor IIH helicase subunit XPB × 1 (P19447) General transcription and DNA repair factor IIH helicase subunit XPD × 1 (P18074) Alpha-amanitin × 1 (P85421) RNA × 1 Transcription initiation factor TFIID subunit 1 × 1 (P21675) Transcription initiation factor TFIID subunit 2 × 1 (Q6P1X5) Transcription initiation factor TFIID subunit 4 × 2 (O00268) Transcription initiation factor TFIID subunit 5 × 2 (Q15542) Transcription initiation factor TFIID subunit 6 × 2 (P49848) Transcription initiation factor TFIID subunit 7 × 1 (Q15545) Transcription initiation factor TFIID subunit 8 × 1 (Q7Z7C8) Transcription initiation factor TFIID subunit 9 × 2 (Q16594) Transcription initiation factor TFIID subunit 10 × 2 (Q12962) Transcription initiation factor TFIID subunit 12 × 2 (Q16514) Transcription initiation factor IIA subunit 2 × 1 (P52657) TATA-box-binding protein × 1 (P20226) Transcription initiation factor IIA beta chain × 1 (P52655) Transcription initiation factor IIB × 1 (Q00403) General transcription factor IIF subunit 1 × 1 (P35269) General transcription factor IIF subunit 2 × 1 (P13984) General transcription factor IIE subunit 1 × 1 (P29083) Transcription initiation factor IIE subunit beta × 1 (P29084) non-template DNA × 1 template DNA × 1 Transcription initiation factor TFIID subunit 3 × 1 (Q5VWG9) Transcription initiation factor TFIID subunit 11 × 1 (Q15544) Transcription initiation factor TFIID subunit 13 × 1 (Q15543) DNA-directed RNA polymerase subunit × 1 (A0A8D1DPV6) DNA-directed RNA polymerase subunit beta × 1 (A0A4X1TVZ5) DNA-directed RNA polymerase II subunit RPB3 × 1 (I3LCH3) DNA-directed RNA polymerase II subunit RPB4 × 1 (A0A481BYI6) DNA-directed RNA polymerase II subunit E × 1 (A0A4X1VTX4) DNA-directed RNA polymerase II subunit F × 1 (A0A4X1VEK9) DNA-directed RNA polymerase II subunit RPB7 × 1 (A0A4X1VKG7) DNA-directed RNA polymerases I, II, and III subunit RPABC3 × 1 (I3LCB2) DNA-directed RNA polymerase II subunit RPB9 × 1 (P60899) DNA-directed RNA polymerases I, II, and III subunit RPABC5 × 1 (A0A493TD97) DNA-directed RNA polymerase II subunit RPB11-a × 1 (F1RKE4) RPB12 × 1 (A0A4X1TRS6) ZINC ION × 17 IRON/SULFUR CLUSTER × 1 ;[[(2~{S},3~{R},4~{S},5~{R})-5-(2-azanyl-6-oxidanylidene-3~{H}-purin-9-yl)-3-methoxy-4-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate ; × 1 MAGNESIUM ION × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name TF2H5_HUMAN
Isoform —
PDB entities 6
Chains and sequence ranges Author chain 5; PDBConstruct 1–71; UniProt 1–71

General transcription and DNA repair factor IIH helicase subunit XPB

Homo sapiens

UniProt P19447

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Other combination Heteromer Protein 48 DNA 2 RNA 1 CDK-activating kinase assembly factor MAT1 × 1 (P51948) General transcription factor IIH subunit 1 × 1 (P32780) General transcription factor IIH subunit 2 × 1 (Q13888) General transcription factor IIH subunit 3 × 1 (Q13889) General transcription factor IIH subunit 4 × 1 (Q92759) General transcription factor IIH subunit 5 × 1 (Q6ZYL4) General transcription and DNA repair factor IIH helicase subunit XPD × 1 (P18074) Alpha-amanitin × 1 (P85421) RNA × 1 Transcription initiation factor TFIID subunit 1 × 1 (P21675) Transcription initiation factor TFIID subunit 2 × 1 (Q6P1X5) Transcription initiation factor TFIID subunit 4 × 2 (O00268) Transcription initiation factor TFIID subunit 5 × 2 (Q15542) Transcription initiation factor TFIID subunit 6 × 2 (P49848) Transcription initiation factor TFIID subunit 7 × 1 (Q15545) Transcription initiation factor TFIID subunit 8 × 1 (Q7Z7C8) Transcription initiation factor TFIID subunit 9 × 2 (Q16594) Transcription initiation factor TFIID subunit 10 × 2 (Q12962) Transcription initiation factor TFIID subunit 12 × 2 (Q16514) Transcription initiation factor IIA subunit 2 × 1 (P52657) TATA-box-binding protein × 1 (P20226) Transcription initiation factor IIA beta chain × 1 (P52655) Transcription initiation factor IIB × 1 (Q00403) General transcription factor IIF subunit 1 × 1 (P35269) General transcription factor IIF subunit 2 × 1 (P13984) General transcription factor IIE subunit 1 × 1 (P29083) Transcription initiation factor IIE subunit beta × 1 (P29084) non-template DNA × 1 template DNA × 1 Transcription initiation factor TFIID subunit 3 × 1 (Q5VWG9) Transcription initiation factor TFIID subunit 11 × 1 (Q15544) Transcription initiation factor TFIID subunit 13 × 1 (Q15543) DNA-directed RNA polymerase subunit × 1 (A0A8D1DPV6) DNA-directed RNA polymerase subunit beta × 1 (A0A4X1TVZ5) DNA-directed RNA polymerase II subunit RPB3 × 1 (I3LCH3) DNA-directed RNA polymerase II subunit RPB4 × 1 (A0A481BYI6) DNA-directed RNA polymerase II subunit E × 1 (A0A4X1VTX4) DNA-directed RNA polymerase II subunit F × 1 (A0A4X1VEK9) DNA-directed RNA polymerase II subunit RPB7 × 1 (A0A4X1VKG7) DNA-directed RNA polymerases I, II, and III subunit RPABC3 × 1 (I3LCB2) DNA-directed RNA polymerase II subunit RPB9 × 1 (P60899) DNA-directed RNA polymerases I, II, and III subunit RPABC5 × 1 (A0A493TD97) DNA-directed RNA polymerase II subunit RPB11-a × 1 (F1RKE4) RPB12 × 1 (A0A4X1TRS6) ZINC ION × 17 IRON/SULFUR CLUSTER × 1 ;[[(2~{S},3~{R},4~{S},5~{R})-5-(2-azanyl-6-oxidanylidene-3~{H}-purin-9-yl)-3-methoxy-4-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate ; × 1 MAGNESIUM ION × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name ERCC3_HUMAN
Isoform —
PDB entities 7
Chains and sequence ranges Author chain 6; PDBConstruct 1–782; UniProt 1–782

General transcription and DNA repair factor IIH helicase subunit XPD

Homo sapiens

UniProt P18074

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Other combination Heteromer Protein 48 DNA 2 RNA 1 CDK-activating kinase assembly factor MAT1 × 1 (P51948) General transcription factor IIH subunit 1 × 1 (P32780) General transcription factor IIH subunit 2 × 1 (Q13888) General transcription factor IIH subunit 3 × 1 (Q13889) General transcription factor IIH subunit 4 × 1 (Q92759) General transcription factor IIH subunit 5 × 1 (Q6ZYL4) General transcription and DNA repair factor IIH helicase subunit XPB × 1 (P19447) Alpha-amanitin × 1 (P85421) RNA × 1 Transcription initiation factor TFIID subunit 1 × 1 (P21675) Transcription initiation factor TFIID subunit 2 × 1 (Q6P1X5) Transcription initiation factor TFIID subunit 4 × 2 (O00268) Transcription initiation factor TFIID subunit 5 × 2 (Q15542) Transcription initiation factor TFIID subunit 6 × 2 (P49848) Transcription initiation factor TFIID subunit 7 × 1 (Q15545) Transcription initiation factor TFIID subunit 8 × 1 (Q7Z7C8) Transcription initiation factor TFIID subunit 9 × 2 (Q16594) Transcription initiation factor TFIID subunit 10 × 2 (Q12962) Transcription initiation factor TFIID subunit 12 × 2 (Q16514) Transcription initiation factor IIA subunit 2 × 1 (P52657) TATA-box-binding protein × 1 (P20226) Transcription initiation factor IIA beta chain × 1 (P52655) Transcription initiation factor IIB × 1 (Q00403) General transcription factor IIF subunit 1 × 1 (P35269) General transcription factor IIF subunit 2 × 1 (P13984) General transcription factor IIE subunit 1 × 1 (P29083) Transcription initiation factor IIE subunit beta × 1 (P29084) non-template DNA × 1 template DNA × 1 Transcription initiation factor TFIID subunit 3 × 1 (Q5VWG9) Transcription initiation factor TFIID subunit 11 × 1 (Q15544) Transcription initiation factor TFIID subunit 13 × 1 (Q15543) DNA-directed RNA polymerase subunit × 1 (A0A8D1DPV6) DNA-directed RNA polymerase subunit beta × 1 (A0A4X1TVZ5) DNA-directed RNA polymerase II subunit RPB3 × 1 (I3LCH3) DNA-directed RNA polymerase II subunit RPB4 × 1 (A0A481BYI6) DNA-directed RNA polymerase II subunit E × 1 (A0A4X1VTX4) DNA-directed RNA polymerase II subunit F × 1 (A0A4X1VEK9) DNA-directed RNA polymerase II subunit RPB7 × 1 (A0A4X1VKG7) DNA-directed RNA polymerases I, II, and III subunit RPABC3 × 1 (I3LCB2) DNA-directed RNA polymerase II subunit RPB9 × 1 (P60899) DNA-directed RNA polymerases I, II, and III subunit RPABC5 × 1 (A0A493TD97) DNA-directed RNA polymerase II subunit RPB11-a × 1 (F1RKE4) RPB12 × 1 (A0A4X1TRS6) ZINC ION × 17 IRON/SULFUR CLUSTER × 1 ;[[(2~{S},3~{R},4~{S},5~{R})-5-(2-azanyl-6-oxidanylidene-3~{H}-purin-9-yl)-3-methoxy-4-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate ; × 1 MAGNESIUM ION × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name ERCC2_HUMAN
Isoform —
PDB entities 8
Chains and sequence ranges Author chain 7; PDBConstruct 1–760; UniProt 1–760

Alpha-amanitin

OrganismNot specified

UniProt P85421

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Other combination Heteromer Protein 48 DNA 2 RNA 1 CDK-activating kinase assembly factor MAT1 × 1 (P51948) General transcription factor IIH subunit 1 × 1 (P32780) General transcription factor IIH subunit 2 × 1 (Q13888) General transcription factor IIH subunit 3 × 1 (Q13889) General transcription factor IIH subunit 4 × 1 (Q92759) General transcription factor IIH subunit 5 × 1 (Q6ZYL4) General transcription and DNA repair factor IIH helicase subunit XPB × 1 (P19447) General transcription and DNA repair factor IIH helicase subunit XPD × 1 (P18074) RNA × 1 Transcription initiation factor TFIID subunit 1 × 1 (P21675) Transcription initiation factor TFIID subunit 2 × 1 (Q6P1X5) Transcription initiation factor TFIID subunit 4 × 2 (O00268) Transcription initiation factor TFIID subunit 5 × 2 (Q15542) Transcription initiation factor TFIID subunit 6 × 2 (P49848) Transcription initiation factor TFIID subunit 7 × 1 (Q15545) Transcription initiation factor TFIID subunit 8 × 1 (Q7Z7C8) Transcription initiation factor TFIID subunit 9 × 2 (Q16594) Transcription initiation factor TFIID subunit 10 × 2 (Q12962) Transcription initiation factor TFIID subunit 12 × 2 (Q16514) Transcription initiation factor IIA subunit 2 × 1 (P52657) TATA-box-binding protein × 1 (P20226) Transcription initiation factor IIA beta chain × 1 (P52655) Transcription initiation factor IIB × 1 (Q00403) General transcription factor IIF subunit 1 × 1 (P35269) General transcription factor IIF subunit 2 × 1 (P13984) General transcription factor IIE subunit 1 × 1 (P29083) Transcription initiation factor IIE subunit beta × 1 (P29084) non-template DNA × 1 template DNA × 1 Transcription initiation factor TFIID subunit 3 × 1 (Q5VWG9) Transcription initiation factor TFIID subunit 11 × 1 (Q15544) Transcription initiation factor TFIID subunit 13 × 1 (Q15543) DNA-directed RNA polymerase subunit × 1 (A0A8D1DPV6) DNA-directed RNA polymerase subunit beta × 1 (A0A4X1TVZ5) DNA-directed RNA polymerase II subunit RPB3 × 1 (I3LCH3) DNA-directed RNA polymerase II subunit RPB4 × 1 (A0A481BYI6) DNA-directed RNA polymerase II subunit E × 1 (A0A4X1VTX4) DNA-directed RNA polymerase II subunit F × 1 (A0A4X1VEK9) DNA-directed RNA polymerase II subunit RPB7 × 1 (A0A4X1VKG7) DNA-directed RNA polymerases I, II, and III subunit RPABC3 × 1 (I3LCB2) DNA-directed RNA polymerase II subunit RPB9 × 1 (P60899) DNA-directed RNA polymerases I, II, and III subunit RPABC5 × 1 (A0A493TD97) DNA-directed RNA polymerase II subunit RPB11-a × 1 (F1RKE4) RPB12 × 1 (A0A4X1TRS6) ZINC ION × 17 IRON/SULFUR CLUSTER × 1 ;[[(2~{S},3~{R},4~{S},5~{R})-5-(2-azanyl-6-oxidanylidene-3~{H}-purin-9-yl)-3-methoxy-4-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate ; × 1 MAGNESIUM ION × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name AAMAT_AMAPH
Isoform —
PDB entities 9
Chains and sequence ranges Author chain N; PDBConstruct 1–8; UniProt 1–8

Transcription initiation factor TFIID subunit 1

Homo sapiens

UniProt P21675

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Other combination Heteromer Protein 48 DNA 2 RNA 1 CDK-activating kinase assembly factor MAT1 × 1 (P51948) General transcription factor IIH subunit 1 × 1 (P32780) General transcription factor IIH subunit 2 × 1 (Q13888) General transcription factor IIH subunit 3 × 1 (Q13889) General transcription factor IIH subunit 4 × 1 (Q92759) General transcription factor IIH subunit 5 × 1 (Q6ZYL4) General transcription and DNA repair factor IIH helicase subunit XPB × 1 (P19447) General transcription and DNA repair factor IIH helicase subunit XPD × 1 (P18074) Alpha-amanitin × 1 (P85421) RNA × 1 Transcription initiation factor TFIID subunit 2 × 1 (Q6P1X5) Transcription initiation factor TFIID subunit 4 × 2 (O00268) Transcription initiation factor TFIID subunit 5 × 2 (Q15542) Transcription initiation factor TFIID subunit 6 × 2 (P49848) Transcription initiation factor TFIID subunit 7 × 1 (Q15545) Transcription initiation factor TFIID subunit 8 × 1 (Q7Z7C8) Transcription initiation factor TFIID subunit 9 × 2 (Q16594) Transcription initiation factor TFIID subunit 10 × 2 (Q12962) Transcription initiation factor TFIID subunit 12 × 2 (Q16514) Transcription initiation factor IIA subunit 2 × 1 (P52657) TATA-box-binding protein × 1 (P20226) Transcription initiation factor IIA beta chain × 1 (P52655) Transcription initiation factor IIB × 1 (Q00403) General transcription factor IIF subunit 1 × 1 (P35269) General transcription factor IIF subunit 2 × 1 (P13984) General transcription factor IIE subunit 1 × 1 (P29083) Transcription initiation factor IIE subunit beta × 1 (P29084) non-template DNA × 1 template DNA × 1 Transcription initiation factor TFIID subunit 3 × 1 (Q5VWG9) Transcription initiation factor TFIID subunit 11 × 1 (Q15544) Transcription initiation factor TFIID subunit 13 × 1 (Q15543) DNA-directed RNA polymerase subunit × 1 (A0A8D1DPV6) DNA-directed RNA polymerase subunit beta × 1 (A0A4X1TVZ5) DNA-directed RNA polymerase II subunit RPB3 × 1 (I3LCH3) DNA-directed RNA polymerase II subunit RPB4 × 1 (A0A481BYI6) DNA-directed RNA polymerase II subunit E × 1 (A0A4X1VTX4) DNA-directed RNA polymerase II subunit F × 1 (A0A4X1VEK9) DNA-directed RNA polymerase II subunit RPB7 × 1 (A0A4X1VKG7) DNA-directed RNA polymerases I, II, and III subunit RPABC3 × 1 (I3LCB2) DNA-directed RNA polymerase II subunit RPB9 × 1 (P60899) DNA-directed RNA polymerases I, II, and III subunit RPABC5 × 1 (A0A493TD97) DNA-directed RNA polymerase II subunit RPB11-a × 1 (F1RKE4) RPB12 × 1 (A0A4X1TRS6) ZINC ION × 17 IRON/SULFUR CLUSTER × 1 ;[[(2~{S},3~{R},4~{S},5~{R})-5-(2-azanyl-6-oxidanylidene-3~{H}-purin-9-yl)-3-methoxy-4-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate ; × 1 MAGNESIUM ION × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name TAF1_HUMAN
Isoform —
PDB entities 11
Chains and sequence ranges Author chain A; PDBConstruct 1–1872; UniProt 1–1872

Transcription initiation factor TFIID subunit 2

Homo sapiens

UniProt Q6P1X5

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Other combination Heteromer Protein 48 DNA 2 RNA 1 CDK-activating kinase assembly factor MAT1 × 1 (P51948) General transcription factor IIH subunit 1 × 1 (P32780) General transcription factor IIH subunit 2 × 1 (Q13888) General transcription factor IIH subunit 3 × 1 (Q13889) General transcription factor IIH subunit 4 × 1 (Q92759) General transcription factor IIH subunit 5 × 1 (Q6ZYL4) General transcription and DNA repair factor IIH helicase subunit XPB × 1 (P19447) General transcription and DNA repair factor IIH helicase subunit XPD × 1 (P18074) Alpha-amanitin × 1 (P85421) RNA × 1 Transcription initiation factor TFIID subunit 1 × 1 (P21675) Transcription initiation factor TFIID subunit 4 × 2 (O00268) Transcription initiation factor TFIID subunit 5 × 2 (Q15542) Transcription initiation factor TFIID subunit 6 × 2 (P49848) Transcription initiation factor TFIID subunit 7 × 1 (Q15545) Transcription initiation factor TFIID subunit 8 × 1 (Q7Z7C8) Transcription initiation factor TFIID subunit 9 × 2 (Q16594) Transcription initiation factor TFIID subunit 10 × 2 (Q12962) Transcription initiation factor TFIID subunit 12 × 2 (Q16514) Transcription initiation factor IIA subunit 2 × 1 (P52657) TATA-box-binding protein × 1 (P20226) Transcription initiation factor IIA beta chain × 1 (P52655) Transcription initiation factor IIB × 1 (Q00403) General transcription factor IIF subunit 1 × 1 (P35269) General transcription factor IIF subunit 2 × 1 (P13984) General transcription factor IIE subunit 1 × 1 (P29083) Transcription initiation factor IIE subunit beta × 1 (P29084) non-template DNA × 1 template DNA × 1 Transcription initiation factor TFIID subunit 3 × 1 (Q5VWG9) Transcription initiation factor TFIID subunit 11 × 1 (Q15544) Transcription initiation factor TFIID subunit 13 × 1 (Q15543) DNA-directed RNA polymerase subunit × 1 (A0A8D1DPV6) DNA-directed RNA polymerase subunit beta × 1 (A0A4X1TVZ5) DNA-directed RNA polymerase II subunit RPB3 × 1 (I3LCH3) DNA-directed RNA polymerase II subunit RPB4 × 1 (A0A481BYI6) DNA-directed RNA polymerase II subunit E × 1 (A0A4X1VTX4) DNA-directed RNA polymerase II subunit F × 1 (A0A4X1VEK9) DNA-directed RNA polymerase II subunit RPB7 × 1 (A0A4X1VKG7) DNA-directed RNA polymerases I, II, and III subunit RPABC3 × 1 (I3LCB2) DNA-directed RNA polymerase II subunit RPB9 × 1 (P60899) DNA-directed RNA polymerases I, II, and III subunit RPABC5 × 1 (A0A493TD97) DNA-directed RNA polymerase II subunit RPB11-a × 1 (F1RKE4) RPB12 × 1 (A0A4X1TRS6) ZINC ION × 17 IRON/SULFUR CLUSTER × 1 ;[[(2~{S},3~{R},4~{S},5~{R})-5-(2-azanyl-6-oxidanylidene-3~{H}-purin-9-yl)-3-methoxy-4-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate ; × 1 MAGNESIUM ION × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name TAF2_HUMAN
Isoform —
PDB entities 12
Chains and sequence ranges Author chain B; PDBConstruct 1–1199; UniProt 1–1199

Transcription initiation factor TFIID subunit 4

Homo sapiens

UniProt O00268

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Other combination Heteromer Protein 48 DNA 2 RNA 1 CDK-activating kinase assembly factor MAT1 × 1 (P51948) General transcription factor IIH subunit 1 × 1 (P32780) General transcription factor IIH subunit 2 × 1 (Q13888) General transcription factor IIH subunit 3 × 1 (Q13889) General transcription factor IIH subunit 4 × 1 (Q92759) General transcription factor IIH subunit 5 × 1 (Q6ZYL4) General transcription and DNA repair factor IIH helicase subunit XPB × 1 (P19447) General transcription and DNA repair factor IIH helicase subunit XPD × 1 (P18074) Alpha-amanitin × 1 (P85421) RNA × 1 Transcription initiation factor TFIID subunit 1 × 1 (P21675) Transcription initiation factor TFIID subunit 2 × 1 (Q6P1X5) Transcription initiation factor TFIID subunit 5 × 2 (Q15542) Transcription initiation factor TFIID subunit 6 × 2 (P49848) Transcription initiation factor TFIID subunit 7 × 1 (Q15545) Transcription initiation factor TFIID subunit 8 × 1 (Q7Z7C8) Transcription initiation factor TFIID subunit 9 × 2 (Q16594) Transcription initiation factor TFIID subunit 10 × 2 (Q12962) Transcription initiation factor TFIID subunit 12 × 2 (Q16514) Transcription initiation factor IIA subunit 2 × 1 (P52657) TATA-box-binding protein × 1 (P20226) Transcription initiation factor IIA beta chain × 1 (P52655) Transcription initiation factor IIB × 1 (Q00403) General transcription factor IIF subunit 1 × 1 (P35269) General transcription factor IIF subunit 2 × 1 (P13984) General transcription factor IIE subunit 1 × 1 (P29083) Transcription initiation factor IIE subunit beta × 1 (P29084) non-template DNA × 1 template DNA × 1 Transcription initiation factor TFIID subunit 3 × 1 (Q5VWG9) Transcription initiation factor TFIID subunit 11 × 1 (Q15544) Transcription initiation factor TFIID subunit 13 × 1 (Q15543) DNA-directed RNA polymerase subunit × 1 (A0A8D1DPV6) DNA-directed RNA polymerase subunit beta × 1 (A0A4X1TVZ5) DNA-directed RNA polymerase II subunit RPB3 × 1 (I3LCH3) DNA-directed RNA polymerase II subunit RPB4 × 1 (A0A481BYI6) DNA-directed RNA polymerase II subunit E × 1 (A0A4X1VTX4) DNA-directed RNA polymerase II subunit F × 1 (A0A4X1VEK9) DNA-directed RNA polymerase II subunit RPB7 × 1 (A0A4X1VKG7) DNA-directed RNA polymerases I, II, and III subunit RPABC3 × 1 (I3LCB2) DNA-directed RNA polymerase II subunit RPB9 × 1 (P60899) DNA-directed RNA polymerases I, II, and III subunit RPABC5 × 1 (A0A493TD97) DNA-directed RNA polymerase II subunit RPB11-a × 1 (F1RKE4) RPB12 × 1 (A0A4X1TRS6) ZINC ION × 17 IRON/SULFUR CLUSTER × 1 ;[[(2~{S},3~{R},4~{S},5~{R})-5-(2-azanyl-6-oxidanylidene-3~{H}-purin-9-yl)-3-methoxy-4-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate ; × 1 MAGNESIUM ION × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name TAF4_HUMAN
Isoform —
PDB entities 13
Chains and sequence ranges Author chain D; PDBConstruct 1–1085; UniProt 1–1085 Author chain d; PDBConstruct 1–1085; UniProt 1–1085

Transcription initiation factor TFIID subunit 5

Homo sapiens

UniProt Q15542

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Other combination Heteromer Protein 48 DNA 2 RNA 1 CDK-activating kinase assembly factor MAT1 × 1 (P51948) General transcription factor IIH subunit 1 × 1 (P32780) General transcription factor IIH subunit 2 × 1 (Q13888) General transcription factor IIH subunit 3 × 1 (Q13889) General transcription factor IIH subunit 4 × 1 (Q92759) General transcription factor IIH subunit 5 × 1 (Q6ZYL4) General transcription and DNA repair factor IIH helicase subunit XPB × 1 (P19447) General transcription and DNA repair factor IIH helicase subunit XPD × 1 (P18074) Alpha-amanitin × 1 (P85421) RNA × 1 Transcription initiation factor TFIID subunit 1 × 1 (P21675) Transcription initiation factor TFIID subunit 2 × 1 (Q6P1X5) Transcription initiation factor TFIID subunit 4 × 2 (O00268) Transcription initiation factor TFIID subunit 6 × 2 (P49848) Transcription initiation factor TFIID subunit 7 × 1 (Q15545) Transcription initiation factor TFIID subunit 8 × 1 (Q7Z7C8) Transcription initiation factor TFIID subunit 9 × 2 (Q16594) Transcription initiation factor TFIID subunit 10 × 2 (Q12962) Transcription initiation factor TFIID subunit 12 × 2 (Q16514) Transcription initiation factor IIA subunit 2 × 1 (P52657) TATA-box-binding protein × 1 (P20226) Transcription initiation factor IIA beta chain × 1 (P52655) Transcription initiation factor IIB × 1 (Q00403) General transcription factor IIF subunit 1 × 1 (P35269) General transcription factor IIF subunit 2 × 1 (P13984) General transcription factor IIE subunit 1 × 1 (P29083) Transcription initiation factor IIE subunit beta × 1 (P29084) non-template DNA × 1 template DNA × 1 Transcription initiation factor TFIID subunit 3 × 1 (Q5VWG9) Transcription initiation factor TFIID subunit 11 × 1 (Q15544) Transcription initiation factor TFIID subunit 13 × 1 (Q15543) DNA-directed RNA polymerase subunit × 1 (A0A8D1DPV6) DNA-directed RNA polymerase subunit beta × 1 (A0A4X1TVZ5) DNA-directed RNA polymerase II subunit RPB3 × 1 (I3LCH3) DNA-directed RNA polymerase II subunit RPB4 × 1 (A0A481BYI6) DNA-directed RNA polymerase II subunit E × 1 (A0A4X1VTX4) DNA-directed RNA polymerase II subunit F × 1 (A0A4X1VEK9) DNA-directed RNA polymerase II subunit RPB7 × 1 (A0A4X1VKG7) DNA-directed RNA polymerases I, II, and III subunit RPABC3 × 1 (I3LCB2) DNA-directed RNA polymerase II subunit RPB9 × 1 (P60899) DNA-directed RNA polymerases I, II, and III subunit RPABC5 × 1 (A0A493TD97) DNA-directed RNA polymerase II subunit RPB11-a × 1 (F1RKE4) RPB12 × 1 (A0A4X1TRS6) ZINC ION × 17 IRON/SULFUR CLUSTER × 1 ;[[(2~{S},3~{R},4~{S},5~{R})-5-(2-azanyl-6-oxidanylidene-3~{H}-purin-9-yl)-3-methoxy-4-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate ; × 1 MAGNESIUM ION × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name TAF5_HUMAN
Isoform —
PDB entities 14
Chains and sequence ranges Author chain E; PDBConstruct 1–800; UniProt 1–800 Author chain e; PDBConstruct 1–800; UniProt 1–800

Transcription initiation factor TFIID subunit 6

Homo sapiens

UniProt P49848

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Other combination Heteromer Protein 48 DNA 2 RNA 1 CDK-activating kinase assembly factor MAT1 × 1 (P51948) General transcription factor IIH subunit 1 × 1 (P32780) General transcription factor IIH subunit 2 × 1 (Q13888) General transcription factor IIH subunit 3 × 1 (Q13889) General transcription factor IIH subunit 4 × 1 (Q92759) General transcription factor IIH subunit 5 × 1 (Q6ZYL4) General transcription and DNA repair factor IIH helicase subunit XPB × 1 (P19447) General transcription and DNA repair factor IIH helicase subunit XPD × 1 (P18074) Alpha-amanitin × 1 (P85421) RNA × 1 Transcription initiation factor TFIID subunit 1 × 1 (P21675) Transcription initiation factor TFIID subunit 2 × 1 (Q6P1X5) Transcription initiation factor TFIID subunit 4 × 2 (O00268) Transcription initiation factor TFIID subunit 5 × 2 (Q15542) Transcription initiation factor TFIID subunit 7 × 1 (Q15545) Transcription initiation factor TFIID subunit 8 × 1 (Q7Z7C8) Transcription initiation factor TFIID subunit 9 × 2 (Q16594) Transcription initiation factor TFIID subunit 10 × 2 (Q12962) Transcription initiation factor TFIID subunit 12 × 2 (Q16514) Transcription initiation factor IIA subunit 2 × 1 (P52657) TATA-box-binding protein × 1 (P20226) Transcription initiation factor IIA beta chain × 1 (P52655) Transcription initiation factor IIB × 1 (Q00403) General transcription factor IIF subunit 1 × 1 (P35269) General transcription factor IIF subunit 2 × 1 (P13984) General transcription factor IIE subunit 1 × 1 (P29083) Transcription initiation factor IIE subunit beta × 1 (P29084) non-template DNA × 1 template DNA × 1 Transcription initiation factor TFIID subunit 3 × 1 (Q5VWG9) Transcription initiation factor TFIID subunit 11 × 1 (Q15544) Transcription initiation factor TFIID subunit 13 × 1 (Q15543) DNA-directed RNA polymerase subunit × 1 (A0A8D1DPV6) DNA-directed RNA polymerase subunit beta × 1 (A0A4X1TVZ5) DNA-directed RNA polymerase II subunit RPB3 × 1 (I3LCH3) DNA-directed RNA polymerase II subunit RPB4 × 1 (A0A481BYI6) DNA-directed RNA polymerase II subunit E × 1 (A0A4X1VTX4) DNA-directed RNA polymerase II subunit F × 1 (A0A4X1VEK9) DNA-directed RNA polymerase II subunit RPB7 × 1 (A0A4X1VKG7) DNA-directed RNA polymerases I, II, and III subunit RPABC3 × 1 (I3LCB2) DNA-directed RNA polymerase II subunit RPB9 × 1 (P60899) DNA-directed RNA polymerases I, II, and III subunit RPABC5 × 1 (A0A493TD97) DNA-directed RNA polymerase II subunit RPB11-a × 1 (F1RKE4) RPB12 × 1 (A0A4X1TRS6) ZINC ION × 17 IRON/SULFUR CLUSTER × 1 ;[[(2~{S},3~{R},4~{S},5~{R})-5-(2-azanyl-6-oxidanylidene-3~{H}-purin-9-yl)-3-methoxy-4-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate ; × 1 MAGNESIUM ION × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name TAF6_HUMAN
Isoform —
PDB entities 15
Chains and sequence ranges Author chain F; PDBConstruct 1–677; UniProt 1–677 Author chain f; PDBConstruct 1–677; UniProt 1–677

Transcription initiation factor TFIID subunit 7

Homo sapiens

UniProt Q15545

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Other combination Heteromer Protein 48 DNA 2 RNA 1 CDK-activating kinase assembly factor MAT1 × 1 (P51948) General transcription factor IIH subunit 1 × 1 (P32780) General transcription factor IIH subunit 2 × 1 (Q13888) General transcription factor IIH subunit 3 × 1 (Q13889) General transcription factor IIH subunit 4 × 1 (Q92759) General transcription factor IIH subunit 5 × 1 (Q6ZYL4) General transcription and DNA repair factor IIH helicase subunit XPB × 1 (P19447) General transcription and DNA repair factor IIH helicase subunit XPD × 1 (P18074) Alpha-amanitin × 1 (P85421) RNA × 1 Transcription initiation factor TFIID subunit 1 × 1 (P21675) Transcription initiation factor TFIID subunit 2 × 1 (Q6P1X5) Transcription initiation factor TFIID subunit 4 × 2 (O00268) Transcription initiation factor TFIID subunit 5 × 2 (Q15542) Transcription initiation factor TFIID subunit 6 × 2 (P49848) Transcription initiation factor TFIID subunit 8 × 1 (Q7Z7C8) Transcription initiation factor TFIID subunit 9 × 2 (Q16594) Transcription initiation factor TFIID subunit 10 × 2 (Q12962) Transcription initiation factor TFIID subunit 12 × 2 (Q16514) Transcription initiation factor IIA subunit 2 × 1 (P52657) TATA-box-binding protein × 1 (P20226) Transcription initiation factor IIA beta chain × 1 (P52655) Transcription initiation factor IIB × 1 (Q00403) General transcription factor IIF subunit 1 × 1 (P35269) General transcription factor IIF subunit 2 × 1 (P13984) General transcription factor IIE subunit 1 × 1 (P29083) Transcription initiation factor IIE subunit beta × 1 (P29084) non-template DNA × 1 template DNA × 1 Transcription initiation factor TFIID subunit 3 × 1 (Q5VWG9) Transcription initiation factor TFIID subunit 11 × 1 (Q15544) Transcription initiation factor TFIID subunit 13 × 1 (Q15543) DNA-directed RNA polymerase subunit × 1 (A0A8D1DPV6) DNA-directed RNA polymerase subunit beta × 1 (A0A4X1TVZ5) DNA-directed RNA polymerase II subunit RPB3 × 1 (I3LCH3) DNA-directed RNA polymerase II subunit RPB4 × 1 (A0A481BYI6) DNA-directed RNA polymerase II subunit E × 1 (A0A4X1VTX4) DNA-directed RNA polymerase II subunit F × 1 (A0A4X1VEK9) DNA-directed RNA polymerase II subunit RPB7 × 1 (A0A4X1VKG7) DNA-directed RNA polymerases I, II, and III subunit RPABC3 × 1 (I3LCB2) DNA-directed RNA polymerase II subunit RPB9 × 1 (P60899) DNA-directed RNA polymerases I, II, and III subunit RPABC5 × 1 (A0A493TD97) DNA-directed RNA polymerase II subunit RPB11-a × 1 (F1RKE4) RPB12 × 1 (A0A4X1TRS6) ZINC ION × 17 IRON/SULFUR CLUSTER × 1 ;[[(2~{S},3~{R},4~{S},5~{R})-5-(2-azanyl-6-oxidanylidene-3~{H}-purin-9-yl)-3-methoxy-4-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate ; × 1 MAGNESIUM ION × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name TAF7_HUMAN
Isoform —
PDB entities 16
Chains and sequence ranges Author chain G; PDBConstruct 1–349; UniProt 1–349

Transcription initiation factor TFIID subunit 8

Homo sapiens

UniProt Q7Z7C8

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Other combination Heteromer Protein 48 DNA 2 RNA 1 CDK-activating kinase assembly factor MAT1 × 1 (P51948) General transcription factor IIH subunit 1 × 1 (P32780) General transcription factor IIH subunit 2 × 1 (Q13888) General transcription factor IIH subunit 3 × 1 (Q13889) General transcription factor IIH subunit 4 × 1 (Q92759) General transcription factor IIH subunit 5 × 1 (Q6ZYL4) General transcription and DNA repair factor IIH helicase subunit XPB × 1 (P19447) General transcription and DNA repair factor IIH helicase subunit XPD × 1 (P18074) Alpha-amanitin × 1 (P85421) RNA × 1 Transcription initiation factor TFIID subunit 1 × 1 (P21675) Transcription initiation factor TFIID subunit 2 × 1 (Q6P1X5) Transcription initiation factor TFIID subunit 4 × 2 (O00268) Transcription initiation factor TFIID subunit 5 × 2 (Q15542) Transcription initiation factor TFIID subunit 6 × 2 (P49848) Transcription initiation factor TFIID subunit 7 × 1 (Q15545) Transcription initiation factor TFIID subunit 9 × 2 (Q16594) Transcription initiation factor TFIID subunit 10 × 2 (Q12962) Transcription initiation factor TFIID subunit 12 × 2 (Q16514) Transcription initiation factor IIA subunit 2 × 1 (P52657) TATA-box-binding protein × 1 (P20226) Transcription initiation factor IIA beta chain × 1 (P52655) Transcription initiation factor IIB × 1 (Q00403) General transcription factor IIF subunit 1 × 1 (P35269) General transcription factor IIF subunit 2 × 1 (P13984) General transcription factor IIE subunit 1 × 1 (P29083) Transcription initiation factor IIE subunit beta × 1 (P29084) non-template DNA × 1 template DNA × 1 Transcription initiation factor TFIID subunit 3 × 1 (Q5VWG9) Transcription initiation factor TFIID subunit 11 × 1 (Q15544) Transcription initiation factor TFIID subunit 13 × 1 (Q15543) DNA-directed RNA polymerase subunit × 1 (A0A8D1DPV6) DNA-directed RNA polymerase subunit beta × 1 (A0A4X1TVZ5) DNA-directed RNA polymerase II subunit RPB3 × 1 (I3LCH3) DNA-directed RNA polymerase II subunit RPB4 × 1 (A0A481BYI6) DNA-directed RNA polymerase II subunit E × 1 (A0A4X1VTX4) DNA-directed RNA polymerase II subunit F × 1 (A0A4X1VEK9) DNA-directed RNA polymerase II subunit RPB7 × 1 (A0A4X1VKG7) DNA-directed RNA polymerases I, II, and III subunit RPABC3 × 1 (I3LCB2) DNA-directed RNA polymerase II subunit RPB9 × 1 (P60899) DNA-directed RNA polymerases I, II, and III subunit RPABC5 × 1 (A0A493TD97) DNA-directed RNA polymerase II subunit RPB11-a × 1 (F1RKE4) RPB12 × 1 (A0A4X1TRS6) ZINC ION × 17 IRON/SULFUR CLUSTER × 1 ;[[(2~{S},3~{R},4~{S},5~{R})-5-(2-azanyl-6-oxidanylidene-3~{H}-purin-9-yl)-3-methoxy-4-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate ; × 1 MAGNESIUM ION × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name TAF8_HUMAN
Isoform —
PDB entities 17
Chains and sequence ranges Author chain H; PDBConstruct 1–310; UniProt 1–310

Transcription initiation factor TFIID subunit 9

Homo sapiens

UniProt Q16594

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Other combination Heteromer Protein 48 DNA 2 RNA 1 CDK-activating kinase assembly factor MAT1 × 1 (P51948) General transcription factor IIH subunit 1 × 1 (P32780) General transcription factor IIH subunit 2 × 1 (Q13888) General transcription factor IIH subunit 3 × 1 (Q13889) General transcription factor IIH subunit 4 × 1 (Q92759) General transcription factor IIH subunit 5 × 1 (Q6ZYL4) General transcription and DNA repair factor IIH helicase subunit XPB × 1 (P19447) General transcription and DNA repair factor IIH helicase subunit XPD × 1 (P18074) Alpha-amanitin × 1 (P85421) RNA × 1 Transcription initiation factor TFIID subunit 1 × 1 (P21675) Transcription initiation factor TFIID subunit 2 × 1 (Q6P1X5) Transcription initiation factor TFIID subunit 4 × 2 (O00268) Transcription initiation factor TFIID subunit 5 × 2 (Q15542) Transcription initiation factor TFIID subunit 6 × 2 (P49848) Transcription initiation factor TFIID subunit 7 × 1 (Q15545) Transcription initiation factor TFIID subunit 8 × 1 (Q7Z7C8) Transcription initiation factor TFIID subunit 10 × 2 (Q12962) Transcription initiation factor TFIID subunit 12 × 2 (Q16514) Transcription initiation factor IIA subunit 2 × 1 (P52657) TATA-box-binding protein × 1 (P20226) Transcription initiation factor IIA beta chain × 1 (P52655) Transcription initiation factor IIB × 1 (Q00403) General transcription factor IIF subunit 1 × 1 (P35269) General transcription factor IIF subunit 2 × 1 (P13984) General transcription factor IIE subunit 1 × 1 (P29083) Transcription initiation factor IIE subunit beta × 1 (P29084) non-template DNA × 1 template DNA × 1 Transcription initiation factor TFIID subunit 3 × 1 (Q5VWG9) Transcription initiation factor TFIID subunit 11 × 1 (Q15544) Transcription initiation factor TFIID subunit 13 × 1 (Q15543) DNA-directed RNA polymerase subunit × 1 (A0A8D1DPV6) DNA-directed RNA polymerase subunit beta × 1 (A0A4X1TVZ5) DNA-directed RNA polymerase II subunit RPB3 × 1 (I3LCH3) DNA-directed RNA polymerase II subunit RPB4 × 1 (A0A481BYI6) DNA-directed RNA polymerase II subunit E × 1 (A0A4X1VTX4) DNA-directed RNA polymerase II subunit F × 1 (A0A4X1VEK9) DNA-directed RNA polymerase II subunit RPB7 × 1 (A0A4X1VKG7) DNA-directed RNA polymerases I, II, and III subunit RPABC3 × 1 (I3LCB2) DNA-directed RNA polymerase II subunit RPB9 × 1 (P60899) DNA-directed RNA polymerases I, II, and III subunit RPABC5 × 1 (A0A493TD97) DNA-directed RNA polymerase II subunit RPB11-a × 1 (F1RKE4) RPB12 × 1 (A0A4X1TRS6) ZINC ION × 17 IRON/SULFUR CLUSTER × 1 ;[[(2~{S},3~{R},4~{S},5~{R})-5-(2-azanyl-6-oxidanylidene-3~{H}-purin-9-yl)-3-methoxy-4-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate ; × 1 MAGNESIUM ION × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name TAF9_HUMAN
Isoform —
PDB entities 18
Chains and sequence ranges Author chain I; PDBConstruct 1–264; UniProt 1–264 Author chain i; PDBConstruct 1–264; UniProt 1–264

Transcription initiation factor TFIID subunit 10

Homo sapiens

UniProt Q12962

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Other combination Heteromer Protein 48 DNA 2 RNA 1 CDK-activating kinase assembly factor MAT1 × 1 (P51948) General transcription factor IIH subunit 1 × 1 (P32780) General transcription factor IIH subunit 2 × 1 (Q13888) General transcription factor IIH subunit 3 × 1 (Q13889) General transcription factor IIH subunit 4 × 1 (Q92759) General transcription factor IIH subunit 5 × 1 (Q6ZYL4) General transcription and DNA repair factor IIH helicase subunit XPB × 1 (P19447) General transcription and DNA repair factor IIH helicase subunit XPD × 1 (P18074) Alpha-amanitin × 1 (P85421) RNA × 1 Transcription initiation factor TFIID subunit 1 × 1 (P21675) Transcription initiation factor TFIID subunit 2 × 1 (Q6P1X5) Transcription initiation factor TFIID subunit 4 × 2 (O00268) Transcription initiation factor TFIID subunit 5 × 2 (Q15542) Transcription initiation factor TFIID subunit 6 × 2 (P49848) Transcription initiation factor TFIID subunit 7 × 1 (Q15545) Transcription initiation factor TFIID subunit 8 × 1 (Q7Z7C8) Transcription initiation factor TFIID subunit 9 × 2 (Q16594) Transcription initiation factor TFIID subunit 12 × 2 (Q16514) Transcription initiation factor IIA subunit 2 × 1 (P52657) TATA-box-binding protein × 1 (P20226) Transcription initiation factor IIA beta chain × 1 (P52655) Transcription initiation factor IIB × 1 (Q00403) General transcription factor IIF subunit 1 × 1 (P35269) General transcription factor IIF subunit 2 × 1 (P13984) General transcription factor IIE subunit 1 × 1 (P29083) Transcription initiation factor IIE subunit beta × 1 (P29084) non-template DNA × 1 template DNA × 1 Transcription initiation factor TFIID subunit 3 × 1 (Q5VWG9) Transcription initiation factor TFIID subunit 11 × 1 (Q15544) Transcription initiation factor TFIID subunit 13 × 1 (Q15543) DNA-directed RNA polymerase subunit × 1 (A0A8D1DPV6) DNA-directed RNA polymerase subunit beta × 1 (A0A4X1TVZ5) DNA-directed RNA polymerase II subunit RPB3 × 1 (I3LCH3) DNA-directed RNA polymerase II subunit RPB4 × 1 (A0A481BYI6) DNA-directed RNA polymerase II subunit E × 1 (A0A4X1VTX4) DNA-directed RNA polymerase II subunit F × 1 (A0A4X1VEK9) DNA-directed RNA polymerase II subunit RPB7 × 1 (A0A4X1VKG7) DNA-directed RNA polymerases I, II, and III subunit RPABC3 × 1 (I3LCB2) DNA-directed RNA polymerase II subunit RPB9 × 1 (P60899) DNA-directed RNA polymerases I, II, and III subunit RPABC5 × 1 (A0A493TD97) DNA-directed RNA polymerase II subunit RPB11-a × 1 (F1RKE4) RPB12 × 1 (A0A4X1TRS6) ZINC ION × 17 IRON/SULFUR CLUSTER × 1 ;[[(2~{S},3~{R},4~{S},5~{R})-5-(2-azanyl-6-oxidanylidene-3~{H}-purin-9-yl)-3-methoxy-4-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate ; × 1 MAGNESIUM ION × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name TAF10_HUMAN
Isoform —
PDB entities 19
Chains and sequence ranges Author chain J; PDBConstruct 1–218; UniProt 1–218 Author chain j; PDBConstruct 1–218; UniProt 1–218

Transcription initiation factor TFIID subunit 12

Homo sapiens

UniProt Q16514

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Other combination Heteromer Protein 48 DNA 2 RNA 1 CDK-activating kinase assembly factor MAT1 × 1 (P51948) General transcription factor IIH subunit 1 × 1 (P32780) General transcription factor IIH subunit 2 × 1 (Q13888) General transcription factor IIH subunit 3 × 1 (Q13889) General transcription factor IIH subunit 4 × 1 (Q92759) General transcription factor IIH subunit 5 × 1 (Q6ZYL4) General transcription and DNA repair factor IIH helicase subunit XPB × 1 (P19447) General transcription and DNA repair factor IIH helicase subunit XPD × 1 (P18074) Alpha-amanitin × 1 (P85421) RNA × 1 Transcription initiation factor TFIID subunit 1 × 1 (P21675) Transcription initiation factor TFIID subunit 2 × 1 (Q6P1X5) Transcription initiation factor TFIID subunit 4 × 2 (O00268) Transcription initiation factor TFIID subunit 5 × 2 (Q15542) Transcription initiation factor TFIID subunit 6 × 2 (P49848) Transcription initiation factor TFIID subunit 7 × 1 (Q15545) Transcription initiation factor TFIID subunit 8 × 1 (Q7Z7C8) Transcription initiation factor TFIID subunit 9 × 2 (Q16594) Transcription initiation factor TFIID subunit 10 × 2 (Q12962) Transcription initiation factor IIA subunit 2 × 1 (P52657) TATA-box-binding protein × 1 (P20226) Transcription initiation factor IIA beta chain × 1 (P52655) Transcription initiation factor IIB × 1 (Q00403) General transcription factor IIF subunit 1 × 1 (P35269) General transcription factor IIF subunit 2 × 1 (P13984) General transcription factor IIE subunit 1 × 1 (P29083) Transcription initiation factor IIE subunit beta × 1 (P29084) non-template DNA × 1 template DNA × 1 Transcription initiation factor TFIID subunit 3 × 1 (Q5VWG9) Transcription initiation factor TFIID subunit 11 × 1 (Q15544) Transcription initiation factor TFIID subunit 13 × 1 (Q15543) DNA-directed RNA polymerase subunit × 1 (A0A8D1DPV6) DNA-directed RNA polymerase subunit beta × 1 (A0A4X1TVZ5) DNA-directed RNA polymerase II subunit RPB3 × 1 (I3LCH3) DNA-directed RNA polymerase II subunit RPB4 × 1 (A0A481BYI6) DNA-directed RNA polymerase II subunit E × 1 (A0A4X1VTX4) DNA-directed RNA polymerase II subunit F × 1 (A0A4X1VEK9) DNA-directed RNA polymerase II subunit RPB7 × 1 (A0A4X1VKG7) DNA-directed RNA polymerases I, II, and III subunit RPABC3 × 1 (I3LCB2) DNA-directed RNA polymerase II subunit RPB9 × 1 (P60899) DNA-directed RNA polymerases I, II, and III subunit RPABC5 × 1 (A0A493TD97) DNA-directed RNA polymerase II subunit RPB11-a × 1 (F1RKE4) RPB12 × 1 (A0A4X1TRS6) ZINC ION × 17 IRON/SULFUR CLUSTER × 1 ;[[(2~{S},3~{R},4~{S},5~{R})-5-(2-azanyl-6-oxidanylidene-3~{H}-purin-9-yl)-3-methoxy-4-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate ; × 1 MAGNESIUM ION × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name TAF12_HUMAN
Isoform —
PDB entities 20
Chains and sequence ranges Author chain L; PDBConstruct 1–161; UniProt 1–161 Author chain l; PDBConstruct 1–161; UniProt 1–161

Transcription initiation factor IIA subunit 2

Homo sapiens

UniProt P52657

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Other combination Heteromer Protein 48 DNA 2 RNA 1 CDK-activating kinase assembly factor MAT1 × 1 (P51948) General transcription factor IIH subunit 1 × 1 (P32780) General transcription factor IIH subunit 2 × 1 (Q13888) General transcription factor IIH subunit 3 × 1 (Q13889) General transcription factor IIH subunit 4 × 1 (Q92759) General transcription factor IIH subunit 5 × 1 (Q6ZYL4) General transcription and DNA repair factor IIH helicase subunit XPB × 1 (P19447) General transcription and DNA repair factor IIH helicase subunit XPD × 1 (P18074) Alpha-amanitin × 1 (P85421) RNA × 1 Transcription initiation factor TFIID subunit 1 × 1 (P21675) Transcription initiation factor TFIID subunit 2 × 1 (Q6P1X5) Transcription initiation factor TFIID subunit 4 × 2 (O00268) Transcription initiation factor TFIID subunit 5 × 2 (Q15542) Transcription initiation factor TFIID subunit 6 × 2 (P49848) Transcription initiation factor TFIID subunit 7 × 1 (Q15545) Transcription initiation factor TFIID subunit 8 × 1 (Q7Z7C8) Transcription initiation factor TFIID subunit 9 × 2 (Q16594) Transcription initiation factor TFIID subunit 10 × 2 (Q12962) Transcription initiation factor TFIID subunit 12 × 2 (Q16514) TATA-box-binding protein × 1 (P20226) Transcription initiation factor IIA beta chain × 1 (P52655) Transcription initiation factor IIB × 1 (Q00403) General transcription factor IIF subunit 1 × 1 (P35269) General transcription factor IIF subunit 2 × 1 (P13984) General transcription factor IIE subunit 1 × 1 (P29083) Transcription initiation factor IIE subunit beta × 1 (P29084) non-template DNA × 1 template DNA × 1 Transcription initiation factor TFIID subunit 3 × 1 (Q5VWG9) Transcription initiation factor TFIID subunit 11 × 1 (Q15544) Transcription initiation factor TFIID subunit 13 × 1 (Q15543) DNA-directed RNA polymerase subunit × 1 (A0A8D1DPV6) DNA-directed RNA polymerase subunit beta × 1 (A0A4X1TVZ5) DNA-directed RNA polymerase II subunit RPB3 × 1 (I3LCH3) DNA-directed RNA polymerase II subunit RPB4 × 1 (A0A481BYI6) DNA-directed RNA polymerase II subunit E × 1 (A0A4X1VTX4) DNA-directed RNA polymerase II subunit F × 1 (A0A4X1VEK9) DNA-directed RNA polymerase II subunit RPB7 × 1 (A0A4X1VKG7) DNA-directed RNA polymerases I, II, and III subunit RPABC3 × 1 (I3LCB2) DNA-directed RNA polymerase II subunit RPB9 × 1 (P60899) DNA-directed RNA polymerases I, II, and III subunit RPABC5 × 1 (A0A493TD97) DNA-directed RNA polymerase II subunit RPB11-a × 1 (F1RKE4) RPB12 × 1 (A0A4X1TRS6) ZINC ION × 17 IRON/SULFUR CLUSTER × 1 ;[[(2~{S},3~{R},4~{S},5~{R})-5-(2-azanyl-6-oxidanylidene-3~{H}-purin-9-yl)-3-methoxy-4-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate ; × 1 MAGNESIUM ION × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name T2AG_HUMAN
Isoform —
PDB entities 21
Chains and sequence ranges Author chain O; PDBConstruct 1–109; UniProt 1–109

TATA-box-binding protein

Homo sapiens

UniProt P20226

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Other combination Heteromer Protein 48 DNA 2 RNA 1 CDK-activating kinase assembly factor MAT1 × 1 (P51948) General transcription factor IIH subunit 1 × 1 (P32780) General transcription factor IIH subunit 2 × 1 (Q13888) General transcription factor IIH subunit 3 × 1 (Q13889) General transcription factor IIH subunit 4 × 1 (Q92759) General transcription factor IIH subunit 5 × 1 (Q6ZYL4) General transcription and DNA repair factor IIH helicase subunit XPB × 1 (P19447) General transcription and DNA repair factor IIH helicase subunit XPD × 1 (P18074) Alpha-amanitin × 1 (P85421) RNA × 1 Transcription initiation factor TFIID subunit 1 × 1 (P21675) Transcription initiation factor TFIID subunit 2 × 1 (Q6P1X5) Transcription initiation factor TFIID subunit 4 × 2 (O00268) Transcription initiation factor TFIID subunit 5 × 2 (Q15542) Transcription initiation factor TFIID subunit 6 × 2 (P49848) Transcription initiation factor TFIID subunit 7 × 1 (Q15545) Transcription initiation factor TFIID subunit 8 × 1 (Q7Z7C8) Transcription initiation factor TFIID subunit 9 × 2 (Q16594) Transcription initiation factor TFIID subunit 10 × 2 (Q12962) Transcription initiation factor TFIID subunit 12 × 2 (Q16514) Transcription initiation factor IIA subunit 2 × 1 (P52657) Transcription initiation factor IIA beta chain × 1 (P52655) Transcription initiation factor IIB × 1 (Q00403) General transcription factor IIF subunit 1 × 1 (P35269) General transcription factor IIF subunit 2 × 1 (P13984) General transcription factor IIE subunit 1 × 1 (P29083) Transcription initiation factor IIE subunit beta × 1 (P29084) non-template DNA × 1 template DNA × 1 Transcription initiation factor TFIID subunit 3 × 1 (Q5VWG9) Transcription initiation factor TFIID subunit 11 × 1 (Q15544) Transcription initiation factor TFIID subunit 13 × 1 (Q15543) DNA-directed RNA polymerase subunit × 1 (A0A8D1DPV6) DNA-directed RNA polymerase subunit beta × 1 (A0A4X1TVZ5) DNA-directed RNA polymerase II subunit RPB3 × 1 (I3LCH3) DNA-directed RNA polymerase II subunit RPB4 × 1 (A0A481BYI6) DNA-directed RNA polymerase II subunit E × 1 (A0A4X1VTX4) DNA-directed RNA polymerase II subunit F × 1 (A0A4X1VEK9) DNA-directed RNA polymerase II subunit RPB7 × 1 (A0A4X1VKG7) DNA-directed RNA polymerases I, II, and III subunit RPABC3 × 1 (I3LCB2) DNA-directed RNA polymerase II subunit RPB9 × 1 (P60899) DNA-directed RNA polymerases I, II, and III subunit RPABC5 × 1 (A0A493TD97) DNA-directed RNA polymerase II subunit RPB11-a × 1 (F1RKE4) RPB12 × 1 (A0A4X1TRS6) ZINC ION × 17 IRON/SULFUR CLUSTER × 1 ;[[(2~{S},3~{R},4~{S},5~{R})-5-(2-azanyl-6-oxidanylidene-3~{H}-purin-9-yl)-3-methoxy-4-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate ; × 1 MAGNESIUM ION × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name TBP_HUMAN
Isoform —
PDB entities 22
Chains and sequence ranges Author chain P; PDBConstruct 1–339; UniProt 1–339

Transcription initiation factor IIA beta chain

Homo sapiens

UniProt P52655

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Other combination Heteromer Protein 48 DNA 2 RNA 1 CDK-activating kinase assembly factor MAT1 × 1 (P51948) General transcription factor IIH subunit 1 × 1 (P32780) General transcription factor IIH subunit 2 × 1 (Q13888) General transcription factor IIH subunit 3 × 1 (Q13889) General transcription factor IIH subunit 4 × 1 (Q92759) General transcription factor IIH subunit 5 × 1 (Q6ZYL4) General transcription and DNA repair factor IIH helicase subunit XPB × 1 (P19447) General transcription and DNA repair factor IIH helicase subunit XPD × 1 (P18074) Alpha-amanitin × 1 (P85421) RNA × 1 Transcription initiation factor TFIID subunit 1 × 1 (P21675) Transcription initiation factor TFIID subunit 2 × 1 (Q6P1X5) Transcription initiation factor TFIID subunit 4 × 2 (O00268) Transcription initiation factor TFIID subunit 5 × 2 (Q15542) Transcription initiation factor TFIID subunit 6 × 2 (P49848) Transcription initiation factor TFIID subunit 7 × 1 (Q15545) Transcription initiation factor TFIID subunit 8 × 1 (Q7Z7C8) Transcription initiation factor TFIID subunit 9 × 2 (Q16594) Transcription initiation factor TFIID subunit 10 × 2 (Q12962) Transcription initiation factor TFIID subunit 12 × 2 (Q16514) Transcription initiation factor IIA subunit 2 × 1 (P52657) TATA-box-binding protein × 1 (P20226) Transcription initiation factor IIB × 1 (Q00403) General transcription factor IIF subunit 1 × 1 (P35269) General transcription factor IIF subunit 2 × 1 (P13984) General transcription factor IIE subunit 1 × 1 (P29083) Transcription initiation factor IIE subunit beta × 1 (P29084) non-template DNA × 1 template DNA × 1 Transcription initiation factor TFIID subunit 3 × 1 (Q5VWG9) Transcription initiation factor TFIID subunit 11 × 1 (Q15544) Transcription initiation factor TFIID subunit 13 × 1 (Q15543) DNA-directed RNA polymerase subunit × 1 (A0A8D1DPV6) DNA-directed RNA polymerase subunit beta × 1 (A0A4X1TVZ5) DNA-directed RNA polymerase II subunit RPB3 × 1 (I3LCH3) DNA-directed RNA polymerase II subunit RPB4 × 1 (A0A481BYI6) DNA-directed RNA polymerase II subunit E × 1 (A0A4X1VTX4) DNA-directed RNA polymerase II subunit F × 1 (A0A4X1VEK9) DNA-directed RNA polymerase II subunit RPB7 × 1 (A0A4X1VKG7) DNA-directed RNA polymerases I, II, and III subunit RPABC3 × 1 (I3LCB2) DNA-directed RNA polymerase II subunit RPB9 × 1 (P60899) DNA-directed RNA polymerases I, II, and III subunit RPABC5 × 1 (A0A493TD97) DNA-directed RNA polymerase II subunit RPB11-a × 1 (F1RKE4) RPB12 × 1 (A0A4X1TRS6) ZINC ION × 17 IRON/SULFUR CLUSTER × 1 ;[[(2~{S},3~{R},4~{S},5~{R})-5-(2-azanyl-6-oxidanylidene-3~{H}-purin-9-yl)-3-methoxy-4-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate ; × 1 MAGNESIUM ION × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name TF2AA_HUMAN
Isoform —
PDB entities 23
Chains and sequence ranges Author chain Q; PDBConstruct 1–376; UniProt 1–376

Transcription initiation factor IIB

Homo sapiens

UniProt Q00403

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Other combination Heteromer Protein 48 DNA 2 RNA 1 CDK-activating kinase assembly factor MAT1 × 1 (P51948) General transcription factor IIH subunit 1 × 1 (P32780) General transcription factor IIH subunit 2 × 1 (Q13888) General transcription factor IIH subunit 3 × 1 (Q13889) General transcription factor IIH subunit 4 × 1 (Q92759) General transcription factor IIH subunit 5 × 1 (Q6ZYL4) General transcription and DNA repair factor IIH helicase subunit XPB × 1 (P19447) General transcription and DNA repair factor IIH helicase subunit XPD × 1 (P18074) Alpha-amanitin × 1 (P85421) RNA × 1 Transcription initiation factor TFIID subunit 1 × 1 (P21675) Transcription initiation factor TFIID subunit 2 × 1 (Q6P1X5) Transcription initiation factor TFIID subunit 4 × 2 (O00268) Transcription initiation factor TFIID subunit 5 × 2 (Q15542) Transcription initiation factor TFIID subunit 6 × 2 (P49848) Transcription initiation factor TFIID subunit 7 × 1 (Q15545) Transcription initiation factor TFIID subunit 8 × 1 (Q7Z7C8) Transcription initiation factor TFIID subunit 9 × 2 (Q16594) Transcription initiation factor TFIID subunit 10 × 2 (Q12962) Transcription initiation factor TFIID subunit 12 × 2 (Q16514) Transcription initiation factor IIA subunit 2 × 1 (P52657) TATA-box-binding protein × 1 (P20226) Transcription initiation factor IIA beta chain × 1 (P52655) General transcription factor IIF subunit 1 × 1 (P35269) General transcription factor IIF subunit 2 × 1 (P13984) General transcription factor IIE subunit 1 × 1 (P29083) Transcription initiation factor IIE subunit beta × 1 (P29084) non-template DNA × 1 template DNA × 1 Transcription initiation factor TFIID subunit 3 × 1 (Q5VWG9) Transcription initiation factor TFIID subunit 11 × 1 (Q15544) Transcription initiation factor TFIID subunit 13 × 1 (Q15543) DNA-directed RNA polymerase subunit × 1 (A0A8D1DPV6) DNA-directed RNA polymerase subunit beta × 1 (A0A4X1TVZ5) DNA-directed RNA polymerase II subunit RPB3 × 1 (I3LCH3) DNA-directed RNA polymerase II subunit RPB4 × 1 (A0A481BYI6) DNA-directed RNA polymerase II subunit E × 1 (A0A4X1VTX4) DNA-directed RNA polymerase II subunit F × 1 (A0A4X1VEK9) DNA-directed RNA polymerase II subunit RPB7 × 1 (A0A4X1VKG7) DNA-directed RNA polymerases I, II, and III subunit RPABC3 × 1 (I3LCB2) DNA-directed RNA polymerase II subunit RPB9 × 1 (P60899) DNA-directed RNA polymerases I, II, and III subunit RPABC5 × 1 (A0A493TD97) DNA-directed RNA polymerase II subunit RPB11-a × 1 (F1RKE4) RPB12 × 1 (A0A4X1TRS6) ZINC ION × 17 IRON/SULFUR CLUSTER × 1 ;[[(2~{S},3~{R},4~{S},5~{R})-5-(2-azanyl-6-oxidanylidene-3~{H}-purin-9-yl)-3-methoxy-4-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate ; × 1 MAGNESIUM ION × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name TF2B_HUMAN
Isoform —
PDB entities 24
Chains and sequence ranges Author chain R; PDBConstruct 1–316; UniProt 1–316

General transcription factor IIF subunit 1

Homo sapiens

UniProt P35269

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Other combination Heteromer Protein 48 DNA 2 RNA 1 CDK-activating kinase assembly factor MAT1 × 1 (P51948) General transcription factor IIH subunit 1 × 1 (P32780) General transcription factor IIH subunit 2 × 1 (Q13888) General transcription factor IIH subunit 3 × 1 (Q13889) General transcription factor IIH subunit 4 × 1 (Q92759) General transcription factor IIH subunit 5 × 1 (Q6ZYL4) General transcription and DNA repair factor IIH helicase subunit XPB × 1 (P19447) General transcription and DNA repair factor IIH helicase subunit XPD × 1 (P18074) Alpha-amanitin × 1 (P85421) RNA × 1 Transcription initiation factor TFIID subunit 1 × 1 (P21675) Transcription initiation factor TFIID subunit 2 × 1 (Q6P1X5) Transcription initiation factor TFIID subunit 4 × 2 (O00268) Transcription initiation factor TFIID subunit 5 × 2 (Q15542) Transcription initiation factor TFIID subunit 6 × 2 (P49848) Transcription initiation factor TFIID subunit 7 × 1 (Q15545) Transcription initiation factor TFIID subunit 8 × 1 (Q7Z7C8) Transcription initiation factor TFIID subunit 9 × 2 (Q16594) Transcription initiation factor TFIID subunit 10 × 2 (Q12962) Transcription initiation factor TFIID subunit 12 × 2 (Q16514) Transcription initiation factor IIA subunit 2 × 1 (P52657) TATA-box-binding protein × 1 (P20226) Transcription initiation factor IIA beta chain × 1 (P52655) Transcription initiation factor IIB × 1 (Q00403) General transcription factor IIF subunit 2 × 1 (P13984) General transcription factor IIE subunit 1 × 1 (P29083) Transcription initiation factor IIE subunit beta × 1 (P29084) non-template DNA × 1 template DNA × 1 Transcription initiation factor TFIID subunit 3 × 1 (Q5VWG9) Transcription initiation factor TFIID subunit 11 × 1 (Q15544) Transcription initiation factor TFIID subunit 13 × 1 (Q15543) DNA-directed RNA polymerase subunit × 1 (A0A8D1DPV6) DNA-directed RNA polymerase subunit beta × 1 (A0A4X1TVZ5) DNA-directed RNA polymerase II subunit RPB3 × 1 (I3LCH3) DNA-directed RNA polymerase II subunit RPB4 × 1 (A0A481BYI6) DNA-directed RNA polymerase II subunit E × 1 (A0A4X1VTX4) DNA-directed RNA polymerase II subunit F × 1 (A0A4X1VEK9) DNA-directed RNA polymerase II subunit RPB7 × 1 (A0A4X1VKG7) DNA-directed RNA polymerases I, II, and III subunit RPABC3 × 1 (I3LCB2) DNA-directed RNA polymerase II subunit RPB9 × 1 (P60899) DNA-directed RNA polymerases I, II, and III subunit RPABC5 × 1 (A0A493TD97) DNA-directed RNA polymerase II subunit RPB11-a × 1 (F1RKE4) RPB12 × 1 (A0A4X1TRS6) ZINC ION × 17 IRON/SULFUR CLUSTER × 1 ;[[(2~{S},3~{R},4~{S},5~{R})-5-(2-azanyl-6-oxidanylidene-3~{H}-purin-9-yl)-3-methoxy-4-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate ; × 1 MAGNESIUM ION × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name T2FA_HUMAN
Isoform —
PDB entities 25
Chains and sequence ranges Author chain S; PDBConstruct 1–517; UniProt 1–517

General transcription factor IIF subunit 2

Homo sapiens

UniProt P13984

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Other combination Heteromer Protein 48 DNA 2 RNA 1 CDK-activating kinase assembly factor MAT1 × 1 (P51948) General transcription factor IIH subunit 1 × 1 (P32780) General transcription factor IIH subunit 2 × 1 (Q13888) General transcription factor IIH subunit 3 × 1 (Q13889) General transcription factor IIH subunit 4 × 1 (Q92759) General transcription factor IIH subunit 5 × 1 (Q6ZYL4) General transcription and DNA repair factor IIH helicase subunit XPB × 1 (P19447) General transcription and DNA repair factor IIH helicase subunit XPD × 1 (P18074) Alpha-amanitin × 1 (P85421) RNA × 1 Transcription initiation factor TFIID subunit 1 × 1 (P21675) Transcription initiation factor TFIID subunit 2 × 1 (Q6P1X5) Transcription initiation factor TFIID subunit 4 × 2 (O00268) Transcription initiation factor TFIID subunit 5 × 2 (Q15542) Transcription initiation factor TFIID subunit 6 × 2 (P49848) Transcription initiation factor TFIID subunit 7 × 1 (Q15545) Transcription initiation factor TFIID subunit 8 × 1 (Q7Z7C8) Transcription initiation factor TFIID subunit 9 × 2 (Q16594) Transcription initiation factor TFIID subunit 10 × 2 (Q12962) Transcription initiation factor TFIID subunit 12 × 2 (Q16514) Transcription initiation factor IIA subunit 2 × 1 (P52657) TATA-box-binding protein × 1 (P20226) Transcription initiation factor IIA beta chain × 1 (P52655) Transcription initiation factor IIB × 1 (Q00403) General transcription factor IIF subunit 1 × 1 (P35269) General transcription factor IIE subunit 1 × 1 (P29083) Transcription initiation factor IIE subunit beta × 1 (P29084) non-template DNA × 1 template DNA × 1 Transcription initiation factor TFIID subunit 3 × 1 (Q5VWG9) Transcription initiation factor TFIID subunit 11 × 1 (Q15544) Transcription initiation factor TFIID subunit 13 × 1 (Q15543) DNA-directed RNA polymerase subunit × 1 (A0A8D1DPV6) DNA-directed RNA polymerase subunit beta × 1 (A0A4X1TVZ5) DNA-directed RNA polymerase II subunit RPB3 × 1 (I3LCH3) DNA-directed RNA polymerase II subunit RPB4 × 1 (A0A481BYI6) DNA-directed RNA polymerase II subunit E × 1 (A0A4X1VTX4) DNA-directed RNA polymerase II subunit F × 1 (A0A4X1VEK9) DNA-directed RNA polymerase II subunit RPB7 × 1 (A0A4X1VKG7) DNA-directed RNA polymerases I, II, and III subunit RPABC3 × 1 (I3LCB2) DNA-directed RNA polymerase II subunit RPB9 × 1 (P60899) DNA-directed RNA polymerases I, II, and III subunit RPABC5 × 1 (A0A493TD97) DNA-directed RNA polymerase II subunit RPB11-a × 1 (F1RKE4) RPB12 × 1 (A0A4X1TRS6) ZINC ION × 17 IRON/SULFUR CLUSTER × 1 ;[[(2~{S},3~{R},4~{S},5~{R})-5-(2-azanyl-6-oxidanylidene-3~{H}-purin-9-yl)-3-methoxy-4-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate ; × 1 MAGNESIUM ION × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name T2FB_HUMAN
Isoform —
PDB entities 26
Chains and sequence ranges Author chain T; PDBConstruct 1–249; UniProt 1–249

General transcription factor IIE subunit 1

Homo sapiens

UniProt P29083

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Other combination Heteromer Protein 48 DNA 2 RNA 1 CDK-activating kinase assembly factor MAT1 × 1 (P51948) General transcription factor IIH subunit 1 × 1 (P32780) General transcription factor IIH subunit 2 × 1 (Q13888) General transcription factor IIH subunit 3 × 1 (Q13889) General transcription factor IIH subunit 4 × 1 (Q92759) General transcription factor IIH subunit 5 × 1 (Q6ZYL4) General transcription and DNA repair factor IIH helicase subunit XPB × 1 (P19447) General transcription and DNA repair factor IIH helicase subunit XPD × 1 (P18074) Alpha-amanitin × 1 (P85421) RNA × 1 Transcription initiation factor TFIID subunit 1 × 1 (P21675) Transcription initiation factor TFIID subunit 2 × 1 (Q6P1X5) Transcription initiation factor TFIID subunit 4 × 2 (O00268) Transcription initiation factor TFIID subunit 5 × 2 (Q15542) Transcription initiation factor TFIID subunit 6 × 2 (P49848) Transcription initiation factor TFIID subunit 7 × 1 (Q15545) Transcription initiation factor TFIID subunit 8 × 1 (Q7Z7C8) Transcription initiation factor TFIID subunit 9 × 2 (Q16594) Transcription initiation factor TFIID subunit 10 × 2 (Q12962) Transcription initiation factor TFIID subunit 12 × 2 (Q16514) Transcription initiation factor IIA subunit 2 × 1 (P52657) TATA-box-binding protein × 1 (P20226) Transcription initiation factor IIA beta chain × 1 (P52655) Transcription initiation factor IIB × 1 (Q00403) General transcription factor IIF subunit 1 × 1 (P35269) General transcription factor IIF subunit 2 × 1 (P13984) Transcription initiation factor IIE subunit beta × 1 (P29084) non-template DNA × 1 template DNA × 1 Transcription initiation factor TFIID subunit 3 × 1 (Q5VWG9) Transcription initiation factor TFIID subunit 11 × 1 (Q15544) Transcription initiation factor TFIID subunit 13 × 1 (Q15543) DNA-directed RNA polymerase subunit × 1 (A0A8D1DPV6) DNA-directed RNA polymerase subunit beta × 1 (A0A4X1TVZ5) DNA-directed RNA polymerase II subunit RPB3 × 1 (I3LCH3) DNA-directed RNA polymerase II subunit RPB4 × 1 (A0A481BYI6) DNA-directed RNA polymerase II subunit E × 1 (A0A4X1VTX4) DNA-directed RNA polymerase II subunit F × 1 (A0A4X1VEK9) DNA-directed RNA polymerase II subunit RPB7 × 1 (A0A4X1VKG7) DNA-directed RNA polymerases I, II, and III subunit RPABC3 × 1 (I3LCB2) DNA-directed RNA polymerase II subunit RPB9 × 1 (P60899) DNA-directed RNA polymerases I, II, and III subunit RPABC5 × 1 (A0A493TD97) DNA-directed RNA polymerase II subunit RPB11-a × 1 (F1RKE4) RPB12 × 1 (A0A4X1TRS6) ZINC ION × 17 IRON/SULFUR CLUSTER × 1 ;[[(2~{S},3~{R},4~{S},5~{R})-5-(2-azanyl-6-oxidanylidene-3~{H}-purin-9-yl)-3-methoxy-4-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate ; × 1 MAGNESIUM ION × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name T2EA_HUMAN
Isoform —
PDB entities 27
Chains and sequence ranges Author chain U; PDBConstruct 1–439; UniProt 1–439

Transcription initiation factor IIE subunit beta

Homo sapiens

UniProt P29084

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Other combination Heteromer Protein 48 DNA 2 RNA 1 CDK-activating kinase assembly factor MAT1 × 1 (P51948) General transcription factor IIH subunit 1 × 1 (P32780) General transcription factor IIH subunit 2 × 1 (Q13888) General transcription factor IIH subunit 3 × 1 (Q13889) General transcription factor IIH subunit 4 × 1 (Q92759) General transcription factor IIH subunit 5 × 1 (Q6ZYL4) General transcription and DNA repair factor IIH helicase subunit XPB × 1 (P19447) General transcription and DNA repair factor IIH helicase subunit XPD × 1 (P18074) Alpha-amanitin × 1 (P85421) RNA × 1 Transcription initiation factor TFIID subunit 1 × 1 (P21675) Transcription initiation factor TFIID subunit 2 × 1 (Q6P1X5) Transcription initiation factor TFIID subunit 4 × 2 (O00268) Transcription initiation factor TFIID subunit 5 × 2 (Q15542) Transcription initiation factor TFIID subunit 6 × 2 (P49848) Transcription initiation factor TFIID subunit 7 × 1 (Q15545) Transcription initiation factor TFIID subunit 8 × 1 (Q7Z7C8) Transcription initiation factor TFIID subunit 9 × 2 (Q16594) Transcription initiation factor TFIID subunit 10 × 2 (Q12962) Transcription initiation factor TFIID subunit 12 × 2 (Q16514) Transcription initiation factor IIA subunit 2 × 1 (P52657) TATA-box-binding protein × 1 (P20226) Transcription initiation factor IIA beta chain × 1 (P52655) Transcription initiation factor IIB × 1 (Q00403) General transcription factor IIF subunit 1 × 1 (P35269) General transcription factor IIF subunit 2 × 1 (P13984) General transcription factor IIE subunit 1 × 1 (P29083) non-template DNA × 1 template DNA × 1 Transcription initiation factor TFIID subunit 3 × 1 (Q5VWG9) Transcription initiation factor TFIID subunit 11 × 1 (Q15544) Transcription initiation factor TFIID subunit 13 × 1 (Q15543) DNA-directed RNA polymerase subunit × 1 (A0A8D1DPV6) DNA-directed RNA polymerase subunit beta × 1 (A0A4X1TVZ5) DNA-directed RNA polymerase II subunit RPB3 × 1 (I3LCH3) DNA-directed RNA polymerase II subunit RPB4 × 1 (A0A481BYI6) DNA-directed RNA polymerase II subunit E × 1 (A0A4X1VTX4) DNA-directed RNA polymerase II subunit F × 1 (A0A4X1VEK9) DNA-directed RNA polymerase II subunit RPB7 × 1 (A0A4X1VKG7) DNA-directed RNA polymerases I, II, and III subunit RPABC3 × 1 (I3LCB2) DNA-directed RNA polymerase II subunit RPB9 × 1 (P60899) DNA-directed RNA polymerases I, II, and III subunit RPABC5 × 1 (A0A493TD97) DNA-directed RNA polymerase II subunit RPB11-a × 1 (F1RKE4) RPB12 × 1 (A0A4X1TRS6) ZINC ION × 17 IRON/SULFUR CLUSTER × 1 ;[[(2~{S},3~{R},4~{S},5~{R})-5-(2-azanyl-6-oxidanylidene-3~{H}-purin-9-yl)-3-methoxy-4-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate ; × 1 MAGNESIUM ION × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name T2EB_HUMAN
Isoform —
PDB entities 28
Chains and sequence ranges Author chain V; PDBConstruct 1–291; UniProt 1–291

Transcription initiation factor TFIID subunit 3

Homo sapiens

UniProt Q5VWG9

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Other combination Heteromer Protein 48 DNA 2 RNA 1 CDK-activating kinase assembly factor MAT1 × 1 (P51948) General transcription factor IIH subunit 1 × 1 (P32780) General transcription factor IIH subunit 2 × 1 (Q13888) General transcription factor IIH subunit 3 × 1 (Q13889) General transcription factor IIH subunit 4 × 1 (Q92759) General transcription factor IIH subunit 5 × 1 (Q6ZYL4) General transcription and DNA repair factor IIH helicase subunit XPB × 1 (P19447) General transcription and DNA repair factor IIH helicase subunit XPD × 1 (P18074) Alpha-amanitin × 1 (P85421) RNA × 1 Transcription initiation factor TFIID subunit 1 × 1 (P21675) Transcription initiation factor TFIID subunit 2 × 1 (Q6P1X5) Transcription initiation factor TFIID subunit 4 × 2 (O00268) Transcription initiation factor TFIID subunit 5 × 2 (Q15542) Transcription initiation factor TFIID subunit 6 × 2 (P49848) Transcription initiation factor TFIID subunit 7 × 1 (Q15545) Transcription initiation factor TFIID subunit 8 × 1 (Q7Z7C8) Transcription initiation factor TFIID subunit 9 × 2 (Q16594) Transcription initiation factor TFIID subunit 10 × 2 (Q12962) Transcription initiation factor TFIID subunit 12 × 2 (Q16514) Transcription initiation factor IIA subunit 2 × 1 (P52657) TATA-box-binding protein × 1 (P20226) Transcription initiation factor IIA beta chain × 1 (P52655) Transcription initiation factor IIB × 1 (Q00403) General transcription factor IIF subunit 1 × 1 (P35269) General transcription factor IIF subunit 2 × 1 (P13984) General transcription factor IIE subunit 1 × 1 (P29083) Transcription initiation factor IIE subunit beta × 1 (P29084) non-template DNA × 1 template DNA × 1 Transcription initiation factor TFIID subunit 11 × 1 (Q15544) Transcription initiation factor TFIID subunit 13 × 1 (Q15543) DNA-directed RNA polymerase subunit × 1 (A0A8D1DPV6) DNA-directed RNA polymerase subunit beta × 1 (A0A4X1TVZ5) DNA-directed RNA polymerase II subunit RPB3 × 1 (I3LCH3) DNA-directed RNA polymerase II subunit RPB4 × 1 (A0A481BYI6) DNA-directed RNA polymerase II subunit E × 1 (A0A4X1VTX4) DNA-directed RNA polymerase II subunit F × 1 (A0A4X1VEK9) DNA-directed RNA polymerase II subunit RPB7 × 1 (A0A4X1VKG7) DNA-directed RNA polymerases I, II, and III subunit RPABC3 × 1 (I3LCB2) DNA-directed RNA polymerase II subunit RPB9 × 1 (P60899) DNA-directed RNA polymerases I, II, and III subunit RPABC5 × 1 (A0A493TD97) DNA-directed RNA polymerase II subunit RPB11-a × 1 (F1RKE4) RPB12 × 1 (A0A4X1TRS6) ZINC ION × 17 IRON/SULFUR CLUSTER × 1 ;[[(2~{S},3~{R},4~{S},5~{R})-5-(2-azanyl-6-oxidanylidene-3~{H}-purin-9-yl)-3-methoxy-4-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate ; × 1 MAGNESIUM ION × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name TAF3_HUMAN
Isoform —
PDB entities 31
Chains and sequence ranges Author chain c; PDBConstruct 1–929; UniProt 1–929

Transcription initiation factor TFIID subunit 11

Homo sapiens

UniProt Q15544

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Other combination Heteromer Protein 48 DNA 2 RNA 1 CDK-activating kinase assembly factor MAT1 × 1 (P51948) General transcription factor IIH subunit 1 × 1 (P32780) General transcription factor IIH subunit 2 × 1 (Q13888) General transcription factor IIH subunit 3 × 1 (Q13889) General transcription factor IIH subunit 4 × 1 (Q92759) General transcription factor IIH subunit 5 × 1 (Q6ZYL4) General transcription and DNA repair factor IIH helicase subunit XPB × 1 (P19447) General transcription and DNA repair factor IIH helicase subunit XPD × 1 (P18074) Alpha-amanitin × 1 (P85421) RNA × 1 Transcription initiation factor TFIID subunit 1 × 1 (P21675) Transcription initiation factor TFIID subunit 2 × 1 (Q6P1X5) Transcription initiation factor TFIID subunit 4 × 2 (O00268) Transcription initiation factor TFIID subunit 5 × 2 (Q15542) Transcription initiation factor TFIID subunit 6 × 2 (P49848) Transcription initiation factor TFIID subunit 7 × 1 (Q15545) Transcription initiation factor TFIID subunit 8 × 1 (Q7Z7C8) Transcription initiation factor TFIID subunit 9 × 2 (Q16594) Transcription initiation factor TFIID subunit 10 × 2 (Q12962) Transcription initiation factor TFIID subunit 12 × 2 (Q16514) Transcription initiation factor IIA subunit 2 × 1 (P52657) TATA-box-binding protein × 1 (P20226) Transcription initiation factor IIA beta chain × 1 (P52655) Transcription initiation factor IIB × 1 (Q00403) General transcription factor IIF subunit 1 × 1 (P35269) General transcription factor IIF subunit 2 × 1 (P13984) General transcription factor IIE subunit 1 × 1 (P29083) Transcription initiation factor IIE subunit beta × 1 (P29084) non-template DNA × 1 template DNA × 1 Transcription initiation factor TFIID subunit 3 × 1 (Q5VWG9) Transcription initiation factor TFIID subunit 13 × 1 (Q15543) DNA-directed RNA polymerase subunit × 1 (A0A8D1DPV6) DNA-directed RNA polymerase subunit beta × 1 (A0A4X1TVZ5) DNA-directed RNA polymerase II subunit RPB3 × 1 (I3LCH3) DNA-directed RNA polymerase II subunit RPB4 × 1 (A0A481BYI6) DNA-directed RNA polymerase II subunit E × 1 (A0A4X1VTX4) DNA-directed RNA polymerase II subunit F × 1 (A0A4X1VEK9) DNA-directed RNA polymerase II subunit RPB7 × 1 (A0A4X1VKG7) DNA-directed RNA polymerases I, II, and III subunit RPABC3 × 1 (I3LCB2) DNA-directed RNA polymerase II subunit RPB9 × 1 (P60899) DNA-directed RNA polymerases I, II, and III subunit RPABC5 × 1 (A0A493TD97) DNA-directed RNA polymerase II subunit RPB11-a × 1 (F1RKE4) RPB12 × 1 (A0A4X1TRS6) ZINC ION × 17 IRON/SULFUR CLUSTER × 1 ;[[(2~{S},3~{R},4~{S},5~{R})-5-(2-azanyl-6-oxidanylidene-3~{H}-purin-9-yl)-3-methoxy-4-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate ; × 1 MAGNESIUM ION × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name TAF11_HUMAN
Isoform —
PDB entities 32
Chains and sequence ranges Author chain k; PDBConstruct 1–211; UniProt 1–211

Transcription initiation factor TFIID subunit 13

Homo sapiens

UniProt Q15543

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Other combination Heteromer Protein 48 DNA 2 RNA 1 CDK-activating kinase assembly factor MAT1 × 1 (P51948) General transcription factor IIH subunit 1 × 1 (P32780) General transcription factor IIH subunit 2 × 1 (Q13888) General transcription factor IIH subunit 3 × 1 (Q13889) General transcription factor IIH subunit 4 × 1 (Q92759) General transcription factor IIH subunit 5 × 1 (Q6ZYL4) General transcription and DNA repair factor IIH helicase subunit XPB × 1 (P19447) General transcription and DNA repair factor IIH helicase subunit XPD × 1 (P18074) Alpha-amanitin × 1 (P85421) RNA × 1 Transcription initiation factor TFIID subunit 1 × 1 (P21675) Transcription initiation factor TFIID subunit 2 × 1 (Q6P1X5) Transcription initiation factor TFIID subunit 4 × 2 (O00268) Transcription initiation factor TFIID subunit 5 × 2 (Q15542) Transcription initiation factor TFIID subunit 6 × 2 (P49848) Transcription initiation factor TFIID subunit 7 × 1 (Q15545) Transcription initiation factor TFIID subunit 8 × 1 (Q7Z7C8) Transcription initiation factor TFIID subunit 9 × 2 (Q16594) Transcription initiation factor TFIID subunit 10 × 2 (Q12962) Transcription initiation factor TFIID subunit 12 × 2 (Q16514) Transcription initiation factor IIA subunit 2 × 1 (P52657) TATA-box-binding protein × 1 (P20226) Transcription initiation factor IIA beta chain × 1 (P52655) Transcription initiation factor IIB × 1 (Q00403) General transcription factor IIF subunit 1 × 1 (P35269) General transcription factor IIF subunit 2 × 1 (P13984) General transcription factor IIE subunit 1 × 1 (P29083) Transcription initiation factor IIE subunit beta × 1 (P29084) non-template DNA × 1 template DNA × 1 Transcription initiation factor TFIID subunit 3 × 1 (Q5VWG9) Transcription initiation factor TFIID subunit 11 × 1 (Q15544) DNA-directed RNA polymerase subunit × 1 (A0A8D1DPV6) DNA-directed RNA polymerase subunit beta × 1 (A0A4X1TVZ5) DNA-directed RNA polymerase II subunit RPB3 × 1 (I3LCH3) DNA-directed RNA polymerase II subunit RPB4 × 1 (A0A481BYI6) DNA-directed RNA polymerase II subunit E × 1 (A0A4X1VTX4) DNA-directed RNA polymerase II subunit F × 1 (A0A4X1VEK9) DNA-directed RNA polymerase II subunit RPB7 × 1 (A0A4X1VKG7) DNA-directed RNA polymerases I, II, and III subunit RPABC3 × 1 (I3LCB2) DNA-directed RNA polymerase II subunit RPB9 × 1 (P60899) DNA-directed RNA polymerases I, II, and III subunit RPABC5 × 1 (A0A493TD97) DNA-directed RNA polymerase II subunit RPB11-a × 1 (F1RKE4) RPB12 × 1 (A0A4X1TRS6) ZINC ION × 17 IRON/SULFUR CLUSTER × 1 ;[[(2~{S},3~{R},4~{S},5~{R})-5-(2-azanyl-6-oxidanylidene-3~{H}-purin-9-yl)-3-methoxy-4-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate ; × 1 MAGNESIUM ION × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name TAF13_HUMAN
Isoform —
PDB entities 33
Chains and sequence ranges Author chain m; PDBConstruct 1–124; UniProt 1–124

DNA-directed RNA polymerase subunit

OrganismNot specified

UniProt A0A8D1DPV6

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Other combination Heteromer Protein 48 DNA 2 RNA 1 CDK-activating kinase assembly factor MAT1 × 1 (P51948) General transcription factor IIH subunit 1 × 1 (P32780) General transcription factor IIH subunit 2 × 1 (Q13888) General transcription factor IIH subunit 3 × 1 (Q13889) General transcription factor IIH subunit 4 × 1 (Q92759) General transcription factor IIH subunit 5 × 1 (Q6ZYL4) General transcription and DNA repair factor IIH helicase subunit XPB × 1 (P19447) General transcription and DNA repair factor IIH helicase subunit XPD × 1 (P18074) Alpha-amanitin × 1 (P85421) RNA × 1 Transcription initiation factor TFIID subunit 1 × 1 (P21675) Transcription initiation factor TFIID subunit 2 × 1 (Q6P1X5) Transcription initiation factor TFIID subunit 4 × 2 (O00268) Transcription initiation factor TFIID subunit 5 × 2 (Q15542) Transcription initiation factor TFIID subunit 6 × 2 (P49848) Transcription initiation factor TFIID subunit 7 × 1 (Q15545) Transcription initiation factor TFIID subunit 8 × 1 (Q7Z7C8) Transcription initiation factor TFIID subunit 9 × 2 (Q16594) Transcription initiation factor TFIID subunit 10 × 2 (Q12962) Transcription initiation factor TFIID subunit 12 × 2 (Q16514) Transcription initiation factor IIA subunit 2 × 1 (P52657) TATA-box-binding protein × 1 (P20226) Transcription initiation factor IIA beta chain × 1 (P52655) Transcription initiation factor IIB × 1 (Q00403) General transcription factor IIF subunit 1 × 1 (P35269) General transcription factor IIF subunit 2 × 1 (P13984) General transcription factor IIE subunit 1 × 1 (P29083) Transcription initiation factor IIE subunit beta × 1 (P29084) non-template DNA × 1 template DNA × 1 Transcription initiation factor TFIID subunit 3 × 1 (Q5VWG9) Transcription initiation factor TFIID subunit 11 × 1 (Q15544) Transcription initiation factor TFIID subunit 13 × 1 (Q15543) DNA-directed RNA polymerase subunit beta × 1 (A0A4X1TVZ5) DNA-directed RNA polymerase II subunit RPB3 × 1 (I3LCH3) DNA-directed RNA polymerase II subunit RPB4 × 1 (A0A481BYI6) DNA-directed RNA polymerase II subunit E × 1 (A0A4X1VTX4) DNA-directed RNA polymerase II subunit F × 1 (A0A4X1VEK9) DNA-directed RNA polymerase II subunit RPB7 × 1 (A0A4X1VKG7) DNA-directed RNA polymerases I, II, and III subunit RPABC3 × 1 (I3LCB2) DNA-directed RNA polymerase II subunit RPB9 × 1 (P60899) DNA-directed RNA polymerases I, II, and III subunit RPABC5 × 1 (A0A493TD97) DNA-directed RNA polymerase II subunit RPB11-a × 1 (F1RKE4) RPB12 × 1 (A0A4X1TRS6) ZINC ION × 17 IRON/SULFUR CLUSTER × 1 ;[[(2~{S},3~{R},4~{S},5~{R})-5-(2-azanyl-6-oxidanylidene-3~{H}-purin-9-yl)-3-methoxy-4-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate ; × 1 MAGNESIUM ION × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name A0A8D1DPV6_PIG
Isoform —
PDB entities 34
Chains and sequence ranges Author chain o; PDBConstruct 1–1970; UniProt 1–1970

DNA-directed RNA polymerase subunit beta

OrganismNot specified

UniProt A0A4X1TVZ5

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Other combination Heteromer Protein 48 DNA 2 RNA 1 CDK-activating kinase assembly factor MAT1 × 1 (P51948) General transcription factor IIH subunit 1 × 1 (P32780) General transcription factor IIH subunit 2 × 1 (Q13888) General transcription factor IIH subunit 3 × 1 (Q13889) General transcription factor IIH subunit 4 × 1 (Q92759) General transcription factor IIH subunit 5 × 1 (Q6ZYL4) General transcription and DNA repair factor IIH helicase subunit XPB × 1 (P19447) General transcription and DNA repair factor IIH helicase subunit XPD × 1 (P18074) Alpha-amanitin × 1 (P85421) RNA × 1 Transcription initiation factor TFIID subunit 1 × 1 (P21675) Transcription initiation factor TFIID subunit 2 × 1 (Q6P1X5) Transcription initiation factor TFIID subunit 4 × 2 (O00268) Transcription initiation factor TFIID subunit 5 × 2 (Q15542) Transcription initiation factor TFIID subunit 6 × 2 (P49848) Transcription initiation factor TFIID subunit 7 × 1 (Q15545) Transcription initiation factor TFIID subunit 8 × 1 (Q7Z7C8) Transcription initiation factor TFIID subunit 9 × 2 (Q16594) Transcription initiation factor TFIID subunit 10 × 2 (Q12962) Transcription initiation factor TFIID subunit 12 × 2 (Q16514) Transcription initiation factor IIA subunit 2 × 1 (P52657) TATA-box-binding protein × 1 (P20226) Transcription initiation factor IIA beta chain × 1 (P52655) Transcription initiation factor IIB × 1 (Q00403) General transcription factor IIF subunit 1 × 1 (P35269) General transcription factor IIF subunit 2 × 1 (P13984) General transcription factor IIE subunit 1 × 1 (P29083) Transcription initiation factor IIE subunit beta × 1 (P29084) non-template DNA × 1 template DNA × 1 Transcription initiation factor TFIID subunit 3 × 1 (Q5VWG9) Transcription initiation factor TFIID subunit 11 × 1 (Q15544) Transcription initiation factor TFIID subunit 13 × 1 (Q15543) DNA-directed RNA polymerase subunit × 1 (A0A8D1DPV6) DNA-directed RNA polymerase II subunit RPB3 × 1 (I3LCH3) DNA-directed RNA polymerase II subunit RPB4 × 1 (A0A481BYI6) DNA-directed RNA polymerase II subunit E × 1 (A0A4X1VTX4) DNA-directed RNA polymerase II subunit F × 1 (A0A4X1VEK9) DNA-directed RNA polymerase II subunit RPB7 × 1 (A0A4X1VKG7) DNA-directed RNA polymerases I, II, and III subunit RPABC3 × 1 (I3LCB2) DNA-directed RNA polymerase II subunit RPB9 × 1 (P60899) DNA-directed RNA polymerases I, II, and III subunit RPABC5 × 1 (A0A493TD97) DNA-directed RNA polymerase II subunit RPB11-a × 1 (F1RKE4) RPB12 × 1 (A0A4X1TRS6) ZINC ION × 17 IRON/SULFUR CLUSTER × 1 ;[[(2~{S},3~{R},4~{S},5~{R})-5-(2-azanyl-6-oxidanylidene-3~{H}-purin-9-yl)-3-methoxy-4-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate ; × 1 MAGNESIUM ION × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name A0A4X1TVZ5_PIG
Isoform —
PDB entities 35
Chains and sequence ranges Author chain p; PDBConstruct 1–1174; UniProt 78–1251

DNA-directed RNA polymerase II subunit RPB3

OrganismNot specified

UniProt I3LCH3

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Other combination Heteromer Protein 48 DNA 2 RNA 1 CDK-activating kinase assembly factor MAT1 × 1 (P51948) General transcription factor IIH subunit 1 × 1 (P32780) General transcription factor IIH subunit 2 × 1 (Q13888) General transcription factor IIH subunit 3 × 1 (Q13889) General transcription factor IIH subunit 4 × 1 (Q92759) General transcription factor IIH subunit 5 × 1 (Q6ZYL4) General transcription and DNA repair factor IIH helicase subunit XPB × 1 (P19447) General transcription and DNA repair factor IIH helicase subunit XPD × 1 (P18074) Alpha-amanitin × 1 (P85421) RNA × 1 Transcription initiation factor TFIID subunit 1 × 1 (P21675) Transcription initiation factor TFIID subunit 2 × 1 (Q6P1X5) Transcription initiation factor TFIID subunit 4 × 2 (O00268) Transcription initiation factor TFIID subunit 5 × 2 (Q15542) Transcription initiation factor TFIID subunit 6 × 2 (P49848) Transcription initiation factor TFIID subunit 7 × 1 (Q15545) Transcription initiation factor TFIID subunit 8 × 1 (Q7Z7C8) Transcription initiation factor TFIID subunit 9 × 2 (Q16594) Transcription initiation factor TFIID subunit 10 × 2 (Q12962) Transcription initiation factor TFIID subunit 12 × 2 (Q16514) Transcription initiation factor IIA subunit 2 × 1 (P52657) TATA-box-binding protein × 1 (P20226) Transcription initiation factor IIA beta chain × 1 (P52655) Transcription initiation factor IIB × 1 (Q00403) General transcription factor IIF subunit 1 × 1 (P35269) General transcription factor IIF subunit 2 × 1 (P13984) General transcription factor IIE subunit 1 × 1 (P29083) Transcription initiation factor IIE subunit beta × 1 (P29084) non-template DNA × 1 template DNA × 1 Transcription initiation factor TFIID subunit 3 × 1 (Q5VWG9) Transcription initiation factor TFIID subunit 11 × 1 (Q15544) Transcription initiation factor TFIID subunit 13 × 1 (Q15543) DNA-directed RNA polymerase subunit × 1 (A0A8D1DPV6) DNA-directed RNA polymerase subunit beta × 1 (A0A4X1TVZ5) DNA-directed RNA polymerase II subunit RPB4 × 1 (A0A481BYI6) DNA-directed RNA polymerase II subunit E × 1 (A0A4X1VTX4) DNA-directed RNA polymerase II subunit F × 1 (A0A4X1VEK9) DNA-directed RNA polymerase II subunit RPB7 × 1 (A0A4X1VKG7) DNA-directed RNA polymerases I, II, and III subunit RPABC3 × 1 (I3LCB2) DNA-directed RNA polymerase II subunit RPB9 × 1 (P60899) DNA-directed RNA polymerases I, II, and III subunit RPABC5 × 1 (A0A493TD97) DNA-directed RNA polymerase II subunit RPB11-a × 1 (F1RKE4) RPB12 × 1 (A0A4X1TRS6) ZINC ION × 17 IRON/SULFUR CLUSTER × 1 ;[[(2~{S},3~{R},4~{S},5~{R})-5-(2-azanyl-6-oxidanylidene-3~{H}-purin-9-yl)-3-methoxy-4-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate ; × 1 MAGNESIUM ION × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name I3LCH3_PIG
Isoform —
PDB entities 36
Chains and sequence ranges Author chain q; PDBConstruct 1–275; UniProt 1–275

DNA-directed RNA polymerase II subunit RPB4

OrganismNot specified

UniProt A0A481BYI6

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Other combination Heteromer Protein 48 DNA 2 RNA 1 CDK-activating kinase assembly factor MAT1 × 1 (P51948) General transcription factor IIH subunit 1 × 1 (P32780) General transcription factor IIH subunit 2 × 1 (Q13888) General transcription factor IIH subunit 3 × 1 (Q13889) General transcription factor IIH subunit 4 × 1 (Q92759) General transcription factor IIH subunit 5 × 1 (Q6ZYL4) General transcription and DNA repair factor IIH helicase subunit XPB × 1 (P19447) General transcription and DNA repair factor IIH helicase subunit XPD × 1 (P18074) Alpha-amanitin × 1 (P85421) RNA × 1 Transcription initiation factor TFIID subunit 1 × 1 (P21675) Transcription initiation factor TFIID subunit 2 × 1 (Q6P1X5) Transcription initiation factor TFIID subunit 4 × 2 (O00268) Transcription initiation factor TFIID subunit 5 × 2 (Q15542) Transcription initiation factor TFIID subunit 6 × 2 (P49848) Transcription initiation factor TFIID subunit 7 × 1 (Q15545) Transcription initiation factor TFIID subunit 8 × 1 (Q7Z7C8) Transcription initiation factor TFIID subunit 9 × 2 (Q16594) Transcription initiation factor TFIID subunit 10 × 2 (Q12962) Transcription initiation factor TFIID subunit 12 × 2 (Q16514) Transcription initiation factor IIA subunit 2 × 1 (P52657) TATA-box-binding protein × 1 (P20226) Transcription initiation factor IIA beta chain × 1 (P52655) Transcription initiation factor IIB × 1 (Q00403) General transcription factor IIF subunit 1 × 1 (P35269) General transcription factor IIF subunit 2 × 1 (P13984) General transcription factor IIE subunit 1 × 1 (P29083) Transcription initiation factor IIE subunit beta × 1 (P29084) non-template DNA × 1 template DNA × 1 Transcription initiation factor TFIID subunit 3 × 1 (Q5VWG9) Transcription initiation factor TFIID subunit 11 × 1 (Q15544) Transcription initiation factor TFIID subunit 13 × 1 (Q15543) DNA-directed RNA polymerase subunit × 1 (A0A8D1DPV6) DNA-directed RNA polymerase subunit beta × 1 (A0A4X1TVZ5) DNA-directed RNA polymerase II subunit RPB3 × 1 (I3LCH3) DNA-directed RNA polymerase II subunit E × 1 (A0A4X1VTX4) DNA-directed RNA polymerase II subunit F × 1 (A0A4X1VEK9) DNA-directed RNA polymerase II subunit RPB7 × 1 (A0A4X1VKG7) DNA-directed RNA polymerases I, II, and III subunit RPABC3 × 1 (I3LCB2) DNA-directed RNA polymerase II subunit RPB9 × 1 (P60899) DNA-directed RNA polymerases I, II, and III subunit RPABC5 × 1 (A0A493TD97) DNA-directed RNA polymerase II subunit RPB11-a × 1 (F1RKE4) RPB12 × 1 (A0A4X1TRS6) ZINC ION × 17 IRON/SULFUR CLUSTER × 1 ;[[(2~{S},3~{R},4~{S},5~{R})-5-(2-azanyl-6-oxidanylidene-3~{H}-purin-9-yl)-3-methoxy-4-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate ; × 1 MAGNESIUM ION × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name A0A481BYI6_PIG
Isoform —
PDB entities 37
Chains and sequence ranges Author chain r; PDBConstruct 1–142; UniProt 1–142

DNA-directed RNA polymerase II subunit E

OrganismNot specified

UniProt A0A4X1VTX4

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Other combination Heteromer Protein 48 DNA 2 RNA 1 CDK-activating kinase assembly factor MAT1 × 1 (P51948) General transcription factor IIH subunit 1 × 1 (P32780) General transcription factor IIH subunit 2 × 1 (Q13888) General transcription factor IIH subunit 3 × 1 (Q13889) General transcription factor IIH subunit 4 × 1 (Q92759) General transcription factor IIH subunit 5 × 1 (Q6ZYL4) General transcription and DNA repair factor IIH helicase subunit XPB × 1 (P19447) General transcription and DNA repair factor IIH helicase subunit XPD × 1 (P18074) Alpha-amanitin × 1 (P85421) RNA × 1 Transcription initiation factor TFIID subunit 1 × 1 (P21675) Transcription initiation factor TFIID subunit 2 × 1 (Q6P1X5) Transcription initiation factor TFIID subunit 4 × 2 (O00268) Transcription initiation factor TFIID subunit 5 × 2 (Q15542) Transcription initiation factor TFIID subunit 6 × 2 (P49848) Transcription initiation factor TFIID subunit 7 × 1 (Q15545) Transcription initiation factor TFIID subunit 8 × 1 (Q7Z7C8) Transcription initiation factor TFIID subunit 9 × 2 (Q16594) Transcription initiation factor TFIID subunit 10 × 2 (Q12962) Transcription initiation factor TFIID subunit 12 × 2 (Q16514) Transcription initiation factor IIA subunit 2 × 1 (P52657) TATA-box-binding protein × 1 (P20226) Transcription initiation factor IIA beta chain × 1 (P52655) Transcription initiation factor IIB × 1 (Q00403) General transcription factor IIF subunit 1 × 1 (P35269) General transcription factor IIF subunit 2 × 1 (P13984) General transcription factor IIE subunit 1 × 1 (P29083) Transcription initiation factor IIE subunit beta × 1 (P29084) non-template DNA × 1 template DNA × 1 Transcription initiation factor TFIID subunit 3 × 1 (Q5VWG9) Transcription initiation factor TFIID subunit 11 × 1 (Q15544) Transcription initiation factor TFIID subunit 13 × 1 (Q15543) DNA-directed RNA polymerase subunit × 1 (A0A8D1DPV6) DNA-directed RNA polymerase subunit beta × 1 (A0A4X1TVZ5) DNA-directed RNA polymerase II subunit RPB3 × 1 (I3LCH3) DNA-directed RNA polymerase II subunit RPB4 × 1 (A0A481BYI6) DNA-directed RNA polymerase II subunit F × 1 (A0A4X1VEK9) DNA-directed RNA polymerase II subunit RPB7 × 1 (A0A4X1VKG7) DNA-directed RNA polymerases I, II, and III subunit RPABC3 × 1 (I3LCB2) DNA-directed RNA polymerase II subunit RPB9 × 1 (P60899) DNA-directed RNA polymerases I, II, and III subunit RPABC5 × 1 (A0A493TD97) DNA-directed RNA polymerase II subunit RPB11-a × 1 (F1RKE4) RPB12 × 1 (A0A4X1TRS6) ZINC ION × 17 IRON/SULFUR CLUSTER × 1 ;[[(2~{S},3~{R},4~{S},5~{R})-5-(2-azanyl-6-oxidanylidene-3~{H}-purin-9-yl)-3-methoxy-4-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate ; × 1 MAGNESIUM ION × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name A0A4X1VTX4_PIG
Isoform —
PDB entities 38
Chains and sequence ranges Author chain s; PDBConstruct 1–210; UniProt 1–210

DNA-directed RNA polymerase II subunit F

OrganismNot specified

UniProt A0A4X1VEK9

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Other combination Heteromer Protein 48 DNA 2 RNA 1 CDK-activating kinase assembly factor MAT1 × 1 (P51948) General transcription factor IIH subunit 1 × 1 (P32780) General transcription factor IIH subunit 2 × 1 (Q13888) General transcription factor IIH subunit 3 × 1 (Q13889) General transcription factor IIH subunit 4 × 1 (Q92759) General transcription factor IIH subunit 5 × 1 (Q6ZYL4) General transcription and DNA repair factor IIH helicase subunit XPB × 1 (P19447) General transcription and DNA repair factor IIH helicase subunit XPD × 1 (P18074) Alpha-amanitin × 1 (P85421) RNA × 1 Transcription initiation factor TFIID subunit 1 × 1 (P21675) Transcription initiation factor TFIID subunit 2 × 1 (Q6P1X5) Transcription initiation factor TFIID subunit 4 × 2 (O00268) Transcription initiation factor TFIID subunit 5 × 2 (Q15542) Transcription initiation factor TFIID subunit 6 × 2 (P49848) Transcription initiation factor TFIID subunit 7 × 1 (Q15545) Transcription initiation factor TFIID subunit 8 × 1 (Q7Z7C8) Transcription initiation factor TFIID subunit 9 × 2 (Q16594) Transcription initiation factor TFIID subunit 10 × 2 (Q12962) Transcription initiation factor TFIID subunit 12 × 2 (Q16514) Transcription initiation factor IIA subunit 2 × 1 (P52657) TATA-box-binding protein × 1 (P20226) Transcription initiation factor IIA beta chain × 1 (P52655) Transcription initiation factor IIB × 1 (Q00403) General transcription factor IIF subunit 1 × 1 (P35269) General transcription factor IIF subunit 2 × 1 (P13984) General transcription factor IIE subunit 1 × 1 (P29083) Transcription initiation factor IIE subunit beta × 1 (P29084) non-template DNA × 1 template DNA × 1 Transcription initiation factor TFIID subunit 3 × 1 (Q5VWG9) Transcription initiation factor TFIID subunit 11 × 1 (Q15544) Transcription initiation factor TFIID subunit 13 × 1 (Q15543) DNA-directed RNA polymerase subunit × 1 (A0A8D1DPV6) DNA-directed RNA polymerase subunit beta × 1 (A0A4X1TVZ5) DNA-directed RNA polymerase II subunit RPB3 × 1 (I3LCH3) DNA-directed RNA polymerase II subunit RPB4 × 1 (A0A481BYI6) DNA-directed RNA polymerase II subunit E × 1 (A0A4X1VTX4) DNA-directed RNA polymerase II subunit RPB7 × 1 (A0A4X1VKG7) DNA-directed RNA polymerases I, II, and III subunit RPABC3 × 1 (I3LCB2) DNA-directed RNA polymerase II subunit RPB9 × 1 (P60899) DNA-directed RNA polymerases I, II, and III subunit RPABC5 × 1 (A0A493TD97) DNA-directed RNA polymerase II subunit RPB11-a × 1 (F1RKE4) RPB12 × 1 (A0A4X1TRS6) ZINC ION × 17 IRON/SULFUR CLUSTER × 1 ;[[(2~{S},3~{R},4~{S},5~{R})-5-(2-azanyl-6-oxidanylidene-3~{H}-purin-9-yl)-3-methoxy-4-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate ; × 1 MAGNESIUM ION × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name A0A4X1VEK9_PIG
Isoform —
PDB entities 39
Chains and sequence ranges Author chain t; PDBConstruct 1–127; UniProt 1–127

DNA-directed RNA polymerase II subunit RPB7

OrganismNot specified

UniProt A0A4X1VKG7

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Other combination Heteromer Protein 48 DNA 2 RNA 1 CDK-activating kinase assembly factor MAT1 × 1 (P51948) General transcription factor IIH subunit 1 × 1 (P32780) General transcription factor IIH subunit 2 × 1 (Q13888) General transcription factor IIH subunit 3 × 1 (Q13889) General transcription factor IIH subunit 4 × 1 (Q92759) General transcription factor IIH subunit 5 × 1 (Q6ZYL4) General transcription and DNA repair factor IIH helicase subunit XPB × 1 (P19447) General transcription and DNA repair factor IIH helicase subunit XPD × 1 (P18074) Alpha-amanitin × 1 (P85421) RNA × 1 Transcription initiation factor TFIID subunit 1 × 1 (P21675) Transcription initiation factor TFIID subunit 2 × 1 (Q6P1X5) Transcription initiation factor TFIID subunit 4 × 2 (O00268) Transcription initiation factor TFIID subunit 5 × 2 (Q15542) Transcription initiation factor TFIID subunit 6 × 2 (P49848) Transcription initiation factor TFIID subunit 7 × 1 (Q15545) Transcription initiation factor TFIID subunit 8 × 1 (Q7Z7C8) Transcription initiation factor TFIID subunit 9 × 2 (Q16594) Transcription initiation factor TFIID subunit 10 × 2 (Q12962) Transcription initiation factor TFIID subunit 12 × 2 (Q16514) Transcription initiation factor IIA subunit 2 × 1 (P52657) TATA-box-binding protein × 1 (P20226) Transcription initiation factor IIA beta chain × 1 (P52655) Transcription initiation factor IIB × 1 (Q00403) General transcription factor IIF subunit 1 × 1 (P35269) General transcription factor IIF subunit 2 × 1 (P13984) General transcription factor IIE subunit 1 × 1 (P29083) Transcription initiation factor IIE subunit beta × 1 (P29084) non-template DNA × 1 template DNA × 1 Transcription initiation factor TFIID subunit 3 × 1 (Q5VWG9) Transcription initiation factor TFIID subunit 11 × 1 (Q15544) Transcription initiation factor TFIID subunit 13 × 1 (Q15543) DNA-directed RNA polymerase subunit × 1 (A0A8D1DPV6) DNA-directed RNA polymerase subunit beta × 1 (A0A4X1TVZ5) DNA-directed RNA polymerase II subunit RPB3 × 1 (I3LCH3) DNA-directed RNA polymerase II subunit RPB4 × 1 (A0A481BYI6) DNA-directed RNA polymerase II subunit E × 1 (A0A4X1VTX4) DNA-directed RNA polymerase II subunit F × 1 (A0A4X1VEK9) DNA-directed RNA polymerases I, II, and III subunit RPABC3 × 1 (I3LCB2) DNA-directed RNA polymerase II subunit RPB9 × 1 (P60899) DNA-directed RNA polymerases I, II, and III subunit RPABC5 × 1 (A0A493TD97) DNA-directed RNA polymerase II subunit RPB11-a × 1 (F1RKE4) RPB12 × 1 (A0A4X1TRS6) ZINC ION × 17 IRON/SULFUR CLUSTER × 1 ;[[(2~{S},3~{R},4~{S},5~{R})-5-(2-azanyl-6-oxidanylidene-3~{H}-purin-9-yl)-3-methoxy-4-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate ; × 1 MAGNESIUM ION × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name A0A4X1VKG7_PIG
Isoform —
PDB entities 40
Chains and sequence ranges Author chain u; PDBConstruct 1–172; UniProt 1–172

DNA-directed RNA polymerases I, II, and III subunit RPABC3

OrganismNot specified

UniProt I3LCB2

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Other combination Heteromer Protein 48 DNA 2 RNA 1 CDK-activating kinase assembly factor MAT1 × 1 (P51948) General transcription factor IIH subunit 1 × 1 (P32780) General transcription factor IIH subunit 2 × 1 (Q13888) General transcription factor IIH subunit 3 × 1 (Q13889) General transcription factor IIH subunit 4 × 1 (Q92759) General transcription factor IIH subunit 5 × 1 (Q6ZYL4) General transcription and DNA repair factor IIH helicase subunit XPB × 1 (P19447) General transcription and DNA repair factor IIH helicase subunit XPD × 1 (P18074) Alpha-amanitin × 1 (P85421) RNA × 1 Transcription initiation factor TFIID subunit 1 × 1 (P21675) Transcription initiation factor TFIID subunit 2 × 1 (Q6P1X5) Transcription initiation factor TFIID subunit 4 × 2 (O00268) Transcription initiation factor TFIID subunit 5 × 2 (Q15542) Transcription initiation factor TFIID subunit 6 × 2 (P49848) Transcription initiation factor TFIID subunit 7 × 1 (Q15545) Transcription initiation factor TFIID subunit 8 × 1 (Q7Z7C8) Transcription initiation factor TFIID subunit 9 × 2 (Q16594) Transcription initiation factor TFIID subunit 10 × 2 (Q12962) Transcription initiation factor TFIID subunit 12 × 2 (Q16514) Transcription initiation factor IIA subunit 2 × 1 (P52657) TATA-box-binding protein × 1 (P20226) Transcription initiation factor IIA beta chain × 1 (P52655) Transcription initiation factor IIB × 1 (Q00403) General transcription factor IIF subunit 1 × 1 (P35269) General transcription factor IIF subunit 2 × 1 (P13984) General transcription factor IIE subunit 1 × 1 (P29083) Transcription initiation factor IIE subunit beta × 1 (P29084) non-template DNA × 1 template DNA × 1 Transcription initiation factor TFIID subunit 3 × 1 (Q5VWG9) Transcription initiation factor TFIID subunit 11 × 1 (Q15544) Transcription initiation factor TFIID subunit 13 × 1 (Q15543) DNA-directed RNA polymerase subunit × 1 (A0A8D1DPV6) DNA-directed RNA polymerase subunit beta × 1 (A0A4X1TVZ5) DNA-directed RNA polymerase II subunit RPB3 × 1 (I3LCH3) DNA-directed RNA polymerase II subunit RPB4 × 1 (A0A481BYI6) DNA-directed RNA polymerase II subunit E × 1 (A0A4X1VTX4) DNA-directed RNA polymerase II subunit F × 1 (A0A4X1VEK9) DNA-directed RNA polymerase II subunit RPB7 × 1 (A0A4X1VKG7) DNA-directed RNA polymerase II subunit RPB9 × 1 (P60899) DNA-directed RNA polymerases I, II, and III subunit RPABC5 × 1 (A0A493TD97) DNA-directed RNA polymerase II subunit RPB11-a × 1 (F1RKE4) RPB12 × 1 (A0A4X1TRS6) ZINC ION × 17 IRON/SULFUR CLUSTER × 1 ;[[(2~{S},3~{R},4~{S},5~{R})-5-(2-azanyl-6-oxidanylidene-3~{H}-purin-9-yl)-3-methoxy-4-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate ; × 1 MAGNESIUM ION × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name I3LCB2_PIG
Isoform —
PDB entities 41
Chains and sequence ranges Author chain v; PDBConstruct 1–150; UniProt 1–150

DNA-directed RNA polymerase II subunit RPB9

OrganismNot specified

UniProt P60899

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Other combination Heteromer Protein 48 DNA 2 RNA 1 CDK-activating kinase assembly factor MAT1 × 1 (P51948) General transcription factor IIH subunit 1 × 1 (P32780) General transcription factor IIH subunit 2 × 1 (Q13888) General transcription factor IIH subunit 3 × 1 (Q13889) General transcription factor IIH subunit 4 × 1 (Q92759) General transcription factor IIH subunit 5 × 1 (Q6ZYL4) General transcription and DNA repair factor IIH helicase subunit XPB × 1 (P19447) General transcription and DNA repair factor IIH helicase subunit XPD × 1 (P18074) Alpha-amanitin × 1 (P85421) RNA × 1 Transcription initiation factor TFIID subunit 1 × 1 (P21675) Transcription initiation factor TFIID subunit 2 × 1 (Q6P1X5) Transcription initiation factor TFIID subunit 4 × 2 (O00268) Transcription initiation factor TFIID subunit 5 × 2 (Q15542) Transcription initiation factor TFIID subunit 6 × 2 (P49848) Transcription initiation factor TFIID subunit 7 × 1 (Q15545) Transcription initiation factor TFIID subunit 8 × 1 (Q7Z7C8) Transcription initiation factor TFIID subunit 9 × 2 (Q16594) Transcription initiation factor TFIID subunit 10 × 2 (Q12962) Transcription initiation factor TFIID subunit 12 × 2 (Q16514) Transcription initiation factor IIA subunit 2 × 1 (P52657) TATA-box-binding protein × 1 (P20226) Transcription initiation factor IIA beta chain × 1 (P52655) Transcription initiation factor IIB × 1 (Q00403) General transcription factor IIF subunit 1 × 1 (P35269) General transcription factor IIF subunit 2 × 1 (P13984) General transcription factor IIE subunit 1 × 1 (P29083) Transcription initiation factor IIE subunit beta × 1 (P29084) non-template DNA × 1 template DNA × 1 Transcription initiation factor TFIID subunit 3 × 1 (Q5VWG9) Transcription initiation factor TFIID subunit 11 × 1 (Q15544) Transcription initiation factor TFIID subunit 13 × 1 (Q15543) DNA-directed RNA polymerase subunit × 1 (A0A8D1DPV6) DNA-directed RNA polymerase subunit beta × 1 (A0A4X1TVZ5) DNA-directed RNA polymerase II subunit RPB3 × 1 (I3LCH3) DNA-directed RNA polymerase II subunit RPB4 × 1 (A0A481BYI6) DNA-directed RNA polymerase II subunit E × 1 (A0A4X1VTX4) DNA-directed RNA polymerase II subunit F × 1 (A0A4X1VEK9) DNA-directed RNA polymerase II subunit RPB7 × 1 (A0A4X1VKG7) DNA-directed RNA polymerases I, II, and III subunit RPABC3 × 1 (I3LCB2) DNA-directed RNA polymerases I, II, and III subunit RPABC5 × 1 (A0A493TD97) DNA-directed RNA polymerase II subunit RPB11-a × 1 (F1RKE4) RPB12 × 1 (A0A4X1TRS6) ZINC ION × 17 IRON/SULFUR CLUSTER × 1 ;[[(2~{S},3~{R},4~{S},5~{R})-5-(2-azanyl-6-oxidanylidene-3~{H}-purin-9-yl)-3-methoxy-4-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate ; × 1 MAGNESIUM ION × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name RPB9_PIG
Isoform —
PDB entities 42
Chains and sequence ranges Author chain w; PDBConstruct 1–125; UniProt 1–125

DNA-directed RNA polymerases I, II, and III subunit RPABC5

OrganismNot specified

UniProt A0A493TD97

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Other combination Heteromer Protein 48 DNA 2 RNA 1 CDK-activating kinase assembly factor MAT1 × 1 (P51948) General transcription factor IIH subunit 1 × 1 (P32780) General transcription factor IIH subunit 2 × 1 (Q13888) General transcription factor IIH subunit 3 × 1 (Q13889) General transcription factor IIH subunit 4 × 1 (Q92759) General transcription factor IIH subunit 5 × 1 (Q6ZYL4) General transcription and DNA repair factor IIH helicase subunit XPB × 1 (P19447) General transcription and DNA repair factor IIH helicase subunit XPD × 1 (P18074) Alpha-amanitin × 1 (P85421) RNA × 1 Transcription initiation factor TFIID subunit 1 × 1 (P21675) Transcription initiation factor TFIID subunit 2 × 1 (Q6P1X5) Transcription initiation factor TFIID subunit 4 × 2 (O00268) Transcription initiation factor TFIID subunit 5 × 2 (Q15542) Transcription initiation factor TFIID subunit 6 × 2 (P49848) Transcription initiation factor TFIID subunit 7 × 1 (Q15545) Transcription initiation factor TFIID subunit 8 × 1 (Q7Z7C8) Transcription initiation factor TFIID subunit 9 × 2 (Q16594) Transcription initiation factor TFIID subunit 10 × 2 (Q12962) Transcription initiation factor TFIID subunit 12 × 2 (Q16514) Transcription initiation factor IIA subunit 2 × 1 (P52657) TATA-box-binding protein × 1 (P20226) Transcription initiation factor IIA beta chain × 1 (P52655) Transcription initiation factor IIB × 1 (Q00403) General transcription factor IIF subunit 1 × 1 (P35269) General transcription factor IIF subunit 2 × 1 (P13984) General transcription factor IIE subunit 1 × 1 (P29083) Transcription initiation factor IIE subunit beta × 1 (P29084) non-template DNA × 1 template DNA × 1 Transcription initiation factor TFIID subunit 3 × 1 (Q5VWG9) Transcription initiation factor TFIID subunit 11 × 1 (Q15544) Transcription initiation factor TFIID subunit 13 × 1 (Q15543) DNA-directed RNA polymerase subunit × 1 (A0A8D1DPV6) DNA-directed RNA polymerase subunit beta × 1 (A0A4X1TVZ5) DNA-directed RNA polymerase II subunit RPB3 × 1 (I3LCH3) DNA-directed RNA polymerase II subunit RPB4 × 1 (A0A481BYI6) DNA-directed RNA polymerase II subunit E × 1 (A0A4X1VTX4) DNA-directed RNA polymerase II subunit F × 1 (A0A4X1VEK9) DNA-directed RNA polymerase II subunit RPB7 × 1 (A0A4X1VKG7) DNA-directed RNA polymerases I, II, and III subunit RPABC3 × 1 (I3LCB2) DNA-directed RNA polymerase II subunit RPB9 × 1 (P60899) DNA-directed RNA polymerase II subunit RPB11-a × 1 (F1RKE4) RPB12 × 1 (A0A4X1TRS6) ZINC ION × 17 IRON/SULFUR CLUSTER × 1 ;[[(2~{S},3~{R},4~{S},5~{R})-5-(2-azanyl-6-oxidanylidene-3~{H}-purin-9-yl)-3-methoxy-4-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate ; × 1 MAGNESIUM ION × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name A0A493TD97_ANAPP
Isoform —
PDB entities 43
Chains and sequence ranges Author chain x; PDBConstruct 1–67; UniProt 1–67

DNA-directed RNA polymerase II subunit RPB11-a

OrganismNot specified

UniProt F1RKE4

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Other combination Heteromer Protein 48 DNA 2 RNA 1 CDK-activating kinase assembly factor MAT1 × 1 (P51948) General transcription factor IIH subunit 1 × 1 (P32780) General transcription factor IIH subunit 2 × 1 (Q13888) General transcription factor IIH subunit 3 × 1 (Q13889) General transcription factor IIH subunit 4 × 1 (Q92759) General transcription factor IIH subunit 5 × 1 (Q6ZYL4) General transcription and DNA repair factor IIH helicase subunit XPB × 1 (P19447) General transcription and DNA repair factor IIH helicase subunit XPD × 1 (P18074) Alpha-amanitin × 1 (P85421) RNA × 1 Transcription initiation factor TFIID subunit 1 × 1 (P21675) Transcription initiation factor TFIID subunit 2 × 1 (Q6P1X5) Transcription initiation factor TFIID subunit 4 × 2 (O00268) Transcription initiation factor TFIID subunit 5 × 2 (Q15542) Transcription initiation factor TFIID subunit 6 × 2 (P49848) Transcription initiation factor TFIID subunit 7 × 1 (Q15545) Transcription initiation factor TFIID subunit 8 × 1 (Q7Z7C8) Transcription initiation factor TFIID subunit 9 × 2 (Q16594) Transcription initiation factor TFIID subunit 10 × 2 (Q12962) Transcription initiation factor TFIID subunit 12 × 2 (Q16514) Transcription initiation factor IIA subunit 2 × 1 (P52657) TATA-box-binding protein × 1 (P20226) Transcription initiation factor IIA beta chain × 1 (P52655) Transcription initiation factor IIB × 1 (Q00403) General transcription factor IIF subunit 1 × 1 (P35269) General transcription factor IIF subunit 2 × 1 (P13984) General transcription factor IIE subunit 1 × 1 (P29083) Transcription initiation factor IIE subunit beta × 1 (P29084) non-template DNA × 1 template DNA × 1 Transcription initiation factor TFIID subunit 3 × 1 (Q5VWG9) Transcription initiation factor TFIID subunit 11 × 1 (Q15544) Transcription initiation factor TFIID subunit 13 × 1 (Q15543) DNA-directed RNA polymerase subunit × 1 (A0A8D1DPV6) DNA-directed RNA polymerase subunit beta × 1 (A0A4X1TVZ5) DNA-directed RNA polymerase II subunit RPB3 × 1 (I3LCH3) DNA-directed RNA polymerase II subunit RPB4 × 1 (A0A481BYI6) DNA-directed RNA polymerase II subunit E × 1 (A0A4X1VTX4) DNA-directed RNA polymerase II subunit F × 1 (A0A4X1VEK9) DNA-directed RNA polymerase II subunit RPB7 × 1 (A0A4X1VKG7) DNA-directed RNA polymerases I, II, and III subunit RPABC3 × 1 (I3LCB2) DNA-directed RNA polymerase II subunit RPB9 × 1 (P60899) DNA-directed RNA polymerases I, II, and III subunit RPABC5 × 1 (A0A493TD97) RPB12 × 1 (A0A4X1TRS6) ZINC ION × 17 IRON/SULFUR CLUSTER × 1 ;[[(2~{S},3~{R},4~{S},5~{R})-5-(2-azanyl-6-oxidanylidene-3~{H}-purin-9-yl)-3-methoxy-4-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate ; × 1 MAGNESIUM ION × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name F1RKE4_PIG
Isoform —
PDB entities 44
Chains and sequence ranges Author chain y; PDBConstruct 1–117; UniProt 1–117

RPB12

OrganismNot specified

UniProt A0A4X1TRS6

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Other combination Heteromer Protein 48 DNA 2 RNA 1 CDK-activating kinase assembly factor MAT1 × 1 (P51948) General transcription factor IIH subunit 1 × 1 (P32780) General transcription factor IIH subunit 2 × 1 (Q13888) General transcription factor IIH subunit 3 × 1 (Q13889) General transcription factor IIH subunit 4 × 1 (Q92759) General transcription factor IIH subunit 5 × 1 (Q6ZYL4) General transcription and DNA repair factor IIH helicase subunit XPB × 1 (P19447) General transcription and DNA repair factor IIH helicase subunit XPD × 1 (P18074) Alpha-amanitin × 1 (P85421) RNA × 1 Transcription initiation factor TFIID subunit 1 × 1 (P21675) Transcription initiation factor TFIID subunit 2 × 1 (Q6P1X5) Transcription initiation factor TFIID subunit 4 × 2 (O00268) Transcription initiation factor TFIID subunit 5 × 2 (Q15542) Transcription initiation factor TFIID subunit 6 × 2 (P49848) Transcription initiation factor TFIID subunit 7 × 1 (Q15545) Transcription initiation factor TFIID subunit 8 × 1 (Q7Z7C8) Transcription initiation factor TFIID subunit 9 × 2 (Q16594) Transcription initiation factor TFIID subunit 10 × 2 (Q12962) Transcription initiation factor TFIID subunit 12 × 2 (Q16514) Transcription initiation factor IIA subunit 2 × 1 (P52657) TATA-box-binding protein × 1 (P20226) Transcription initiation factor IIA beta chain × 1 (P52655) Transcription initiation factor IIB × 1 (Q00403) General transcription factor IIF subunit 1 × 1 (P35269) General transcription factor IIF subunit 2 × 1 (P13984) General transcription factor IIE subunit 1 × 1 (P29083) Transcription initiation factor IIE subunit beta × 1 (P29084) non-template DNA × 1 template DNA × 1 Transcription initiation factor TFIID subunit 3 × 1 (Q5VWG9) Transcription initiation factor TFIID subunit 11 × 1 (Q15544) Transcription initiation factor TFIID subunit 13 × 1 (Q15543) DNA-directed RNA polymerase subunit × 1 (A0A8D1DPV6) DNA-directed RNA polymerase subunit beta × 1 (A0A4X1TVZ5) DNA-directed RNA polymerase II subunit RPB3 × 1 (I3LCH3) DNA-directed RNA polymerase II subunit RPB4 × 1 (A0A481BYI6) DNA-directed RNA polymerase II subunit E × 1 (A0A4X1VTX4) DNA-directed RNA polymerase II subunit F × 1 (A0A4X1VEK9) DNA-directed RNA polymerase II subunit RPB7 × 1 (A0A4X1VKG7) DNA-directed RNA polymerases I, II, and III subunit RPABC3 × 1 (I3LCB2) DNA-directed RNA polymerase II subunit RPB9 × 1 (P60899) DNA-directed RNA polymerases I, II, and III subunit RPABC5 × 1 (A0A493TD97) DNA-directed RNA polymerase II subunit RPB11-a × 1 (F1RKE4) ZINC ION × 17 IRON/SULFUR CLUSTER × 1 ;[[(2~{S},3~{R},4~{S},5~{R})-5-(2-azanyl-6-oxidanylidene-3~{H}-purin-9-yl)-3-methoxy-4-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate ; × 1 MAGNESIUM ION × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name A0A4X1TRS6_PIG
Isoform —
PDB entities 45
Chains and sequence ranges Author chain z; PDBConstruct 1–58; UniProt 1–58

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id8wal
Deposition date deposition_date2023-09-07
Structure title titleStructure of transcribing complex 3 (TC3), the initially transcribing complex with Pol II positioned 3nt downstream of TSS.
Keywords keywordstranscribing complex, de novo transcription initiation, initially transcribing complex (ITC), TRANSCRIPTION; TRANSCRIPTION
Experimental Method methodELECTRON MICROSCOPY
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

8wal__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

8wal__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 109 1010 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

8wal__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg(Guinier)98.59 Å
Rg (electron density)98.41 Å
Total Rg98.28 Å
Atom count108683
Residues13316
Excluded volume1930300 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 8wal__assembly_1__model_1 51-meric (51) Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (49)

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7. Citations (1)