9ydz

Cryo EM structure of KCa3.1_R355K_II/calmodulin channel in complex with rimtuzalcap

Method: ELECTRON MICROSCOPY
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Intermediate conductance calcium-activated potassium channel protein 4

Homo sapiens

UniProt O15554

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 8 Calmodulin-1 × 4 (P0DP23) POTASSIUM ION × 4 Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name KCNN4_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A; PDBConstruct 1–358; UniProt 9–366 Author chain B; PDBConstruct 1–358; UniProt 9–366 Author chain C; PDBConstruct 1–358; UniProt 9–366 Author chain D; PDBConstruct 1–358; UniProt 9–366

Calmodulin-1

Homo sapiens

UniProt P0DP23

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 8 Intermediate conductance calcium-activated potassium channel protein 4 × 4 (O15554) POTASSIUM ION × 4 Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name CALM1_HUMAN
Isoform —
PDB entities 2
Chains and sequence ranges Author chain E; PDBConstruct 1–67; UniProt 82–148 Author chain F; PDBConstruct 1–67; UniProt 82–148 Author chain G; PDBConstruct 1–67; UniProt 82–148 Author chain H; PDBConstruct 1–67; UniProt 82–148

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id9ydz
Deposition date deposition_date2025-09-23
Structure title titleCryo EM structure of KCa3.1_R355K_II/calmodulin channel in complex with rimtuzalcap
Keywords keywordsIon channel, Intermediate conductance calcium-activated potassium channel, Calmodulin binding protein, TRANSPORT PROTEIN; TRANSPORT PROTEIN
Experimental Method methodELECTRON MICROSCOPY
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

9ydz__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

9ydz__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

9ydz__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg(Guinier)43.40 Å
Rg (electron density)42.06 Å
Total Rg42.12 Å
Atom count12219
Residues1628
Excluded volume219720 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 9ydz__assembly_1__model_1 octameric (8) Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (3)

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7. Citations (1)