SAXSdb — 8d34

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1. Protein Identity and Related Structures Protein Identity & Related Structures

Uridylate-specific endoribonuclease nsp15

Severe acute respiratory syndrome coronavirus 2

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein homooligomer	Homooligomer	Protein 6	No other associated polymer	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	R1AB_SARS2
Isoform	—
PDB entities	1
Chains and sequence ranges	Author chain A； PDBConstruct 28–373； UniProt 6453–6798 Author chain B； PDBConstruct 28–373； UniProt 6453–6798

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id	8d34
Deposition date deposition_date	2022-05-31
Structure title title	Crystal Structure of SARS CoV-2 NSP15 Endroribonuclease H250A
Keywords keywords	Uridylate, Specific, Endoribonuclease, Mutant, SARS-CoV2, RNA BINDING PROTEIN, VIRAL PROTEIN, LYASE; RNA BINDING PROTEIN,VIRAL PROTEIN,LYASE
Experimental Method method	X-RAY DIFFRACTION

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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

8d34__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

8d34__assembly_1__model_1 | I(q)

100 plotted points; both axes use logarithmic scales.

8d34__assembly_1__model_1 | P(r) · Pending

P(r) will be calculated and displayed separately for the same assembly/model.

Rg（Guinier）	40.56 Å
Rg (electron density)	39.90 Å
Total Rg	40.34 Å
Atom count	16464
Residues	2088
Excluded volume	295630 Å³
Maximum q	0.500 Å⁻¹

Assembly	Model	Structure unit	Oligomeric description	Status	CRYSOL	Actions
1	1	`8d34__assembly_1__model_1`	hexameric （6）	Success	4.1.3-1-20251215 (887e7ef)	View Download

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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (1)

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Unit-cell length a length_a	152.525 Å
Unit-cell length b length_b	152.525 Å
Unit-cell length c length_c	109.644 Å
Unit-cell angle α angle_alpha	90.00 °
Unit-cell angle β angle_beta	90.00 °
Unit-cell angle γ angle_gamma	120.00 °
Molecules per unit cell Z z_pdb	12

Space group space_group	P 63
Space-group number int_tables_number	173
Crystal system crystal_system	hexagonal

Resolution resolution	2.910 Å
Low-resolution limit resolution_low	38.130 Å
R factor r_factor	0.2471
R_work r_work	0.2462
R_free r_free	0.2626

Description description	Uridylate-specific endoribonuclease nsp15
Molecular weight formula_weight	41821.4 kDa
EC 编号 ec_number	4.6.1.-
Mutation mutation	H250A
Source method src_method	man
Copy count entity_count	2

Polymer type type	polypeptide(L)
Chain IDs strand_id	A,B
Atom count atom_count	5488

Crystal Structure of SARS CoV-2 NSP15 Endroribonuclease H250A

1. Protein Identity and Related Structures Protein Identity & Related Structures

Uridylate-specific endoribonuclease nsp15

State in the Current Structure

Other States of the Same Protein in the Database

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

8d34__assembly_1__model_1

8d34__assembly_1__model_1 | I(q)

8d34__assembly_1__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

Refinement Refinement

Diffraction experiment Diffraction

5. Entities and Polymers Entities & Polymers (1)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

7. Citations (1)

Source organism organism	Severe acute respiratory syndrome coronavirus 2
NCBI taxonomy ID ncbi_taxonomy_id	2697049
Host organism host_organism	Escherichia coli BL21(DE3)

Crystal Structure of SARS CoV-2 NSP15 Endroribonuclease H250A

1. Protein Identity and Related Structures Protein Identity & Related Structures

Uridylate-specific endoribonuclease nsp15

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

8d34__assembly_1__model_1

8d34__assembly_1__model_1 | I(q)

8d34__assembly_1__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

Refinement Refinement

Diffraction experiment Diffraction

5. Entities and Polymers Entities & Polymers (1)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

7. Citations (1)