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7zl9

Crystal structure of human GPCR Niacin receptor (HCA2)

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Hydroxycarboxylic acid receptor 2,Soluble cytochrome b562

Escherichia coli

UniProt P0ABE7

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Insufficient information Monomer Protein 1 OLEIC ACID × 5 (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 1 DI(HYDROXYETHYL)ETHER × 1 UNKNOWN ATOM OR ION × 5 water × 1 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1apc 1m6t 1qpu 1qq3 256b 256b 2bc5 2bc5 2bc5 2bc5 3fop 3fop

78 assemblies; showing the first 12

Homodimer
1lm3 2bc5 2bc5 3de8 3de8 3hnk 3hnl 3l1m 3tol 3tol 3tom 3tom

35 assemblies; showing the first 12

Homotetramer
2bc5 2bc5 2bc5 2bc5 2qla 3c62 3c63 3de8 3hni 3hni 3hnj 3hnl

36 assemblies; showing the first 12

Other homooligomers
3de9 3foo 3foo 3foo 3foo 3fop 3m15 3m4b 6dhz 6ot4 6ot7 6ot8

39 assemblies; showing the first 12

Heteromeric or nucleic-acid complex
10kt 11td 11tf 11th 11tk 11tl 22em 24xy 24xz 25ik 25il 28vj

635 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name C562_ECOLX
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 326–431； UniProt 23–128

Hydroxycarboxylic acid receptor 2,Soluble cytochrome b562

Escherichia coli

UniProt Q8TDS4

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Insufficient information Monomer Protein 1 OLEIC ACID × 5 (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 1 DI(HYDROXYETHYL)ETHER × 1 UNKNOWN ATOM OR ION × 5 water × 1 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
8k5b 8k5c 8k5d

3 assemblies

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
7xk2 7zl9 7zly 8h2g 8i7v 8i7w 8ihb 8ihf 8ihh 8ihi 8ij3 8ija

37 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name HCAR2_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–325； UniProt 1–325

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id7zl9
Deposition date deposition_date2022-04-14
Structure title titleCrystal structure of human GPCR Niacin receptor (HCA2)
Keywords keywordsNiacin receptor, hydroxycarboxylic acid receptor 2, HCA2, GPCR, membrane protein structure, MEMBRANE PROTEIN; MEMBRANE PROTEIN
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 7zl9__assembly_1__model_1 monomeric （1） Excluded — —
Exclusion reason： The source record does not identify the atom or ion element unambiguously, so a reliable calculation is not possible.
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (6)

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7. Citations (1)