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8rlu

TCR in complex with HLA-E*01:03 bound to HBV envelope 371-379 S3N peptide

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

HLA class I histocompatibility antigen, alpha chain E

Homo sapiens

UniProt P13747

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Insufficient information Heteromer Protein 5 Beta-2-microglobulin × 1 （P61769） Large envelope protein × 1 （Q67953） T cell receptor alpha variable 12-2,T cell receptor alpha chain MC.7.G5 × 1 （A0A075B6T6,P0DTU3） T cell receptor beta variable 6-5,T cell receptor beta chain MC.7.G5 × 1 （A0A0K0K1A5,P0DTU4） water × 5 Consistent with protein count
2 Insufficient information Heteromer Protein 5 Beta-2-microglobulin × 1 （P61769） Large envelope protein × 1 （Q67953） T cell receptor alpha variable 12-2,T cell receptor alpha chain MC.7.G5 × 1 （A0A075B6T6,P0DTU3） T cell receptor beta variable 6-5,T cell receptor beta chain MC.7.G5 × 1 （A0A0K0K1A5,P0DTU4） water × 5 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
1kpr 1kpr 1kpr 1kpr 1ktl 1ktl 1ktl 1mhe 2esv 3am8 3am8 3bze

58 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name HLAE_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–276； UniProt 22–297 Author chain F； PDBConstruct 1–276； UniProt 22–297

Beta-2-microglobulin

Homo sapiens

UniProt P61769

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Insufficient information Heteromer Protein 5 HLA class I histocompatibility antigen, alpha chain E × 1 （P13747） Large envelope protein × 1 （Q67953） T cell receptor alpha variable 12-2,T cell receptor alpha chain MC.7.G5 × 1 （A0A075B6T6,P0DTU3） T cell receptor beta variable 6-5,T cell receptor beta chain MC.7.G5 × 1 （A0A0K0K1A5,P0DTU4） water × 5 Consistent with protein count
2 Insufficient information Heteromer Protein 5 HLA class I histocompatibility antigen, alpha chain E × 1 （P13747） Large envelope protein × 1 （Q67953） T cell receptor alpha variable 12-2,T cell receptor alpha chain MC.7.G5 × 1 （A0A075B6T6,P0DTU3） T cell receptor beta variable 6-5,T cell receptor beta chain MC.7.G5 × 1 （A0A0K0K1A5,P0DTU4） water × 5 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1jnj 1lds 1py4 1py4 1py4 1py4 2d4d 2d4f 2vb5 2xks 2xku 2yxf

61 assemblies; showing the first 12

Homodimer
2x89 2x89 2z9t 3low 4r9h 4r9h 4ra3 4ra3 4rah 6m1b

10 assemblies

Homotetramer
2e8d 2f8o 3tlr 3tm6 3tm6 7afv

6 assemblies

Other homooligomers
3ciq 3ciq 3loz 6gk3 8a7o 8a7p 8a7q 8a7t

8 assemblies

Heteromeric or nucleic-acid complex
1a1m 1a1n 1a1o 1a6z 1a6z 1a9b 1a9b 1a9e 1agb 1agc 1agd 1age

1914 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name B2MG_HUMAN
Isoform —
PDB entities 2
Chains and sequence ranges Author chain B； PDBConstruct 2–100； UniProt 21–119 Author chain G； PDBConstruct 2–100； UniProt 21–119

Large envelope protein

OrganismNot specified

UniProt Q67953

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Insufficient information Heteromer Protein 5 HLA class I histocompatibility antigen, alpha chain E × 1 （P13747） Beta-2-microglobulin × 1 （P61769） T cell receptor alpha variable 12-2,T cell receptor alpha chain MC.7.G5 × 1 （A0A075B6T6,P0DTU3） T cell receptor beta variable 6-5,T cell receptor beta chain MC.7.G5 × 1 （A0A0K0K1A5,P0DTU4） water × 5 Consistent with protein count
2 Insufficient information Heteromer Protein 5 HLA class I histocompatibility antigen, alpha chain E × 1 （P13747） Beta-2-microglobulin × 1 （P61769） T cell receptor alpha variable 12-2,T cell receptor alpha chain MC.7.G5 × 1 （A0A075B6T6,P0DTU3） T cell receptor beta variable 6-5,T cell receptor beta chain MC.7.G5 × 1 （A0A0K0K1A5,P0DTU4） water × 5 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
3zhf 8rlt 8rlt 8rlu 8rlu 8rlv 8rlv

7 assemblies

View Construct and Data Evidence
UniProt name Q67953_HBV
Isoform —
PDB entities 3
Chains and sequence ranges Author chain C； PDBConstruct 1–9； UniProt 427–435 Author chain H； PDBConstruct 1–9； UniProt 427–435

T cell receptor alpha variable 12-2,T cell receptor alpha chain MC.7.G5

Homo sapiens

UniProt A0A075B6T6

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Insufficient information Heteromer Protein 5 HLA class I histocompatibility antigen, alpha chain E × 1 （P13747） Beta-2-microglobulin × 1 （P61769） Large envelope protein × 1 （Q67953） T cell receptor beta variable 6-5,T cell receptor beta chain MC.7.G5 × 1 （A0A0K0K1A5,P0DTU4） water × 5 Consistent with protein count
2 Insufficient information Heteromer Protein 5 HLA class I histocompatibility antigen, alpha chain E × 1 （P13747） Beta-2-microglobulin × 1 （P61769） Large envelope protein × 1 （Q67953） T cell receptor beta variable 6-5,T cell receptor beta chain MC.7.G5 × 1 （A0A0K0K1A5,P0DTU4） water × 5 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
5e9d 5e9d 5nht 5nqk 6dkp 8rlt 8rlt 8rlu 8rlu 8rlv 8rlv

11 assemblies

View Construct and Data Evidence
UniProt name TVAL2_HUMAN
Isoform —
PDB entities 4
Chains and sequence ranges Author chain D； PDBConstruct 3–92； UniProt 23–112 Author chain I； PDBConstruct 3–92； UniProt 23–112

T cell receptor alpha variable 12-2,T cell receptor alpha chain MC.7.G5

Homo sapiens

UniProt P0DTU3

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Insufficient information Heteromer Protein 5 HLA class I histocompatibility antigen, alpha chain E × 1 （P13747） Beta-2-microglobulin × 1 （P61769） Large envelope protein × 1 （Q67953） T cell receptor beta variable 6-5,T cell receptor beta chain MC.7.G5 × 1 （A0A0K0K1A5,P0DTU4） water × 5 Consistent with protein count
2 Insufficient information Heteromer Protein 5 HLA class I histocompatibility antigen, alpha chain E × 1 （P13747） Beta-2-microglobulin × 1 （P61769） Large envelope protein × 1 （Q67953） T cell receptor beta variable 6-5,T cell receptor beta chain MC.7.G5 × 1 （A0A0K0K1A5,P0DTU4） water × 5 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
8rlt 8rlt 8rlu 8rlu 8rlv 8rlv 9hi7 9hi7

8 assemblies

View Construct and Data Evidence
UniProt name TRAR2_HUMAN
Isoform —
PDB entities 4
Chains and sequence ranges Author chain D； PDBConstruct 111–199； UniProt 132–220 Author chain I； PDBConstruct 111–199； UniProt 132–220

T cell receptor beta variable 6-5,T cell receptor beta chain MC.7.G5

Homo sapiens

UniProt A0A0K0K1A5

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Insufficient information Heteromer Protein 5 HLA class I histocompatibility antigen, alpha chain E × 1 （P13747） Beta-2-microglobulin × 1 （P61769） Large envelope protein × 1 （Q67953） T cell receptor alpha variable 12-2,T cell receptor alpha chain MC.7.G5 × 1 （A0A075B6T6,P0DTU3） water × 5 Consistent with protein count
2 Insufficient information Heteromer Protein 5 HLA class I histocompatibility antigen, alpha chain E × 1 （P13747） Beta-2-microglobulin × 1 （P61769） Large envelope protein × 1 （Q67953） T cell receptor alpha variable 12-2,T cell receptor alpha chain MC.7.G5 × 1 （A0A075B6T6,P0DTU3） water × 5 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
5e9d 5e9d 5men 6jxr 6q3s 7fjd 7fje 7fjf 8rlt 8rlt 8rlu 8rlu

16 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name TVB65_HUMAN
Isoform —
PDB entities 5
Chains and sequence ranges Author chain E； PDBConstruct 2–94； UniProt 20–112 Author chain J； PDBConstruct 2–94； UniProt 20–112

T cell receptor beta variable 6-5,T cell receptor beta chain MC.7.G5

Homo sapiens

UniProt P0DTU4

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Insufficient information Heteromer Protein 5 HLA class I histocompatibility antigen, alpha chain E × 1 （P13747） Beta-2-microglobulin × 1 （P61769） Large envelope protein × 1 （Q67953） T cell receptor alpha variable 12-2,T cell receptor alpha chain MC.7.G5 × 1 （A0A075B6T6,P0DTU3） water × 5 Consistent with protein count
2 Insufficient information Heteromer Protein 5 HLA class I histocompatibility antigen, alpha chain E × 1 （P13747） Beta-2-microglobulin × 1 （P61769） Large envelope protein × 1 （Q67953） T cell receptor alpha variable 12-2,T cell receptor alpha chain MC.7.G5 × 1 （A0A075B6T6,P0DTU3） water × 5 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
8rlt 8rlt 8rlu 8rlu 8rlv 8rlv 8t4z 8tw4 8tw6 9hi7 9hi7

11 assemblies

View Construct and Data Evidence
UniProt name TRBR2_HUMAN
Isoform —
PDB entities 5
Chains and sequence ranges Author chain E； PDBConstruct 104–243； UniProt 127–266 Author chain J； PDBConstruct 104–243； UniProt 127–266

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id8rlu
Deposition date deposition_date2024-01-03
Structure title titleTCR in complex with HLA-E*01:03 bound to HBV envelope 371-379 S3N peptide
Keywords keywordsTCR-MHC, TCR, HLA-E, HBV, affinity matured, pHLA, IMMUNE SYSTEM; IMMUNE SYSTEM
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

8rlu__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

8rlu__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

8rlu__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）37.20 Å
Rg (electron density)37.51 Å
Total Rg37.60 Å
Atom count12738
Residues814
Excluded volume114370 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 8rlu__assembly_1__model_1 pentameric （5） Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 8rlu__assembly_2__model_1 pentameric （5） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (6)

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7. Citations (1)